Digital Commons Network^™

Insectdisease: Programmatic Access To The Ecological Database Of The World’S Insect Pathogens, Tad Dallas, Colin J. Carlson, Patrick R. Stephens, Sadie J. Ryan, David W. Onstad

Faculty Publications

Curated databases of species interactions are instrumental to exploring and understanding the spatial distribution of species and their biotic interactions. In the process of conducting such projects, data development and curation efforts may give rise to a data product with utility beyond the scope of the original work, but which becomes inaccessible over time. Data describing insect host–pathogen interactions are fairly rare, and should thus be preserved and curated with appropriate metadata. Here, we introduce the insectDisease R package, a mechanism for curating, updating and distributing data from the Ecological Database of the World's Insect Pathogens, a database of insect …

Association Between Dietary Inflammatory Index Score And Muscle Mass And Strength In Older Adults: A Study From National Health And Nutrition Examination Survey (Nhanes) 1999-2002, Lingzhi Chen, Jingjing Ming, Tianyi Chen, James Hébert Scd, Peng Sun, Li Zhang, Hongya Wang, Qingkuo Wu, Cancan Zhang, Nitin Shivappa Mbbs, Mph, Ph.D., Bo Ban

Faculty Publications

Purpose

Chronic low-grade systemic inflammation affects muscle protein metabolism. The dietary inflammatory index (DII®) is a tool designed to assess the inflammatory potential of the diet. The available data on the association between DII and sarcopenia are limited. We aimed to investigate the association of the DII with components of sarcopenia in individuals over 50 years of age.

Methods

This cross-sectional study used the National Health and Nutrition Examination Survey (NHANES) 1999–2002 dataset. Body composition was measured, and isokinetic strength of the knee extensors (peak force) was evaluated. Low muscle mass and strength were defined using sex-specific thresholds. Energy-adjusted DII …

Recombinant Simian Varicella Virus-Simian Immunodeficiency Virus Vaccine Induces T And B Cell Functions And Provides Partial Protection Against Repeated Mucosal Siv Challenges In Rhesus Macaques, Bapi Pahar, Wayne Gray, Marissa Fahlberg, Brooke Grasperge, Meredith Hunter, Arpita Das, Christopher Mabee, Pyone Pyone Aye, Faith Schiro, Krystle Hensley, Aneeka Ratnayake, Kelly Goff, Celia Labranche, Xiaoying Shen, Georgia D. Tomaras, C. Todd Demarco, David Montefiori, Patricia Kissinger, Preston A. Marx

Faculty and Student Publications

HIV vaccine mediated efficacy, using an expanded live attenuated recombinant varicella virus-vectored SIV rSVV-SIVgag/env vaccine prime with adjuvanted SIV-Env and SIV-Gag protein boosts, was evaluated in a female rhesus macaques (RM) model against repeated intravaginal SIV challenges. Vaccination induced anti-SIV IgG responses and neutralizing antibodies were found in all vaccinated RMs. Three of the eight vaccinated RM remained uninfected (vaccinated and protected, VP) after 13 repeated challenges with the pathogenic SIVmac251-CX-1. The remaining five vaccinated and infected (VI) macaques had significantly reduced plasma viral loads compared with the infected controls (IC). A significant increase in systemic central memory CD4+ T …

Traditional And Virtual Hypertension Self-Management Health Education Program Delivered Through Cooperative Extension, Michelle Parisi, Ellie Lane, Cheryl J. Dye, Rhonda Matthews, Danielle Mcfall, Ethan Bain, Windsor W. Sherrill

Journal of Human Sciences and Extension

Fewer than 25% of individuals in the United States with hypertension have controlled blood pressure (Centers for Disease Control and Prevention, 2021). Hypertension Management Program (HMP) adopted the Health Coaches for Hypertension Control^© (HCHC^©) curriculum and adapted it for delivery by Extension agents. Eight lessons with intermittent health coaching calls were delivered. Pre/post-participation surveys determined changes in knowledge and self-reported weight, systolic (SBP), and diastolic blood pressure (DBP). The pandemic forced a shift in methodology from in-person to virtual delivery, and results were compared. In both traditional and virtual programs, significant differences were found in weight, knowledge …

An Analysis Of Equity In Service Provided By The Snap-Ed Program: A Comparison Of Dietary Outcomes Among African American And White Participants In Louisiana, Matthew Greene, Rhiannon Kroeger, Samuel Stroope, Bailey Houghtaling, Denise Holson

Journal of Human Sciences and Extension

Structural racism has contributed to increased poverty, food insecurity, and obesity rates among African Americans relative to Whites. Nutrition education programs should therefore consider how well they serve this population. The objective of this investigation was to assess whether African American and White Supplemental Nutrition Assistance Program Education (SNAP-Ed) participants in Louisiana had comparable dietary behavior outcomes by conducting secondary data analysis of previous program evaluations from 2017-2018 and 2018-2019 among African American and White SNAP-Ed participants (n = 434). Variables measured included pre- to post-intervention changes in dietary behaviors (e.g., self-reported consumption frequency of fruit, vegetables, whole grains, low-fat …

Full Issue, Volume 10, Number 3, Donna J. Peterson, Scott Cummings

Journal of Human Sciences and Extension

No abstract provided.

Montclair Magazine (Fall/Winter 2022), Montclair State University

Montclair: The magazine of Montclair State University

No abstract provided.

Doxorubicin-Induced Cardiotoxicity Is Mediated By Neutrophils Through Release Of Neutrophil Elastase, Anchit Bhagat

Dissertations and Theses (Open Access)

Doxorubicin (Dox) is one of the most effective chemotherapy agents that is used for the treatment of childhood cancer. Unfortunately Dox treatment can cause damage to the heart. Indeed, childhood cancer survivors are at a higher risk of developing a cardiovascular disease at an earlier age. The mechanisms by which Dox causes acute and late cardiotoxicity are not completely understood. One understudied area in Dox-induced cardiotoxicity is the contribution of inflammation and innate immune cells, in particular neutrophils. Recognizing that neutrophils have been implicated in a number of heart diseases, we evaluated the role of neutrophils in Dox-induced cardiotoxicity. Here, …

Gandy Dancer 11.1, Gandy Dancer

Gandy Dancer Archives

No abstract provided.

Dismembering Monstrous Metaphors In Latinx Speculative Fiction, Danielle Garcia-Karr

Theses and Dissertations

U.S. public discourse and popular media are rife with monstrous metaphors of Latinxs. This thesis argues that these gothic monstrous metaphors construct an affective economy of fear, which results in material violence and the devastation of Latinx lives. I further argue that to intervene within this affective economy, Latinx authors write speculative fiction, employing critical race methodologies, to negotiate monstrosity in relation to citizenship. In other words, speculative Latinx authors disidentify with monsters and enact epistemic disobedience, problematizing the known and naturalized and delinking Latinx people from monstrous metaphors to interrupt cycles of fear and violence. In exploring this metaphoric …

Healthcare In A Time Of Crisis: An Investigation Of The Association Between Socioeconomic Status, Counties, And Covid-19, Jorge F. Contreras

Theses and Dissertations

The COVID-19 pandemic has stressed social structural institutions such as hospitals, schools, the economy, and governmental bodies (local, state, and federal), exacerbating existing health inequality. Fundamental Cause Theory (FCT) provides a framework for understanding which factors drive such inequality, but its primary focus is on within-group variation. By highlighting the role of fundamental causes as systems of exposure, the Systems-of-Exposure (SOE) approach expands on FCT to account for variation more directly between populations. I performed a Qualitative Comparative Analysis (QCA) of county-level data from Texas and California to test the utility of SOE in assessing the impact of a pandemic …

Effects Of Glp-1 Receptor Agonists On Cardiovascular Outcomes In Patients With Type 2 Diabetes And Chronic Kidney Disease: A Systematic Review And Meta-Analysis, Michael Kelly, Jelena Lewis, Hindu Rao, Jessica Carter, Ivan Portillo, Richard Beuttler

College of Pharmacy Faculty Papers

AIM: To evaluate the cardiovascular outcomes of glucagon-like peptide-1 receptor agonists (GLP1-RA) in patients with type 2 diabetes (T2DM) and chronic kidney disease (CKD).

MATERIALS AND METHODS: We searched PubMed, Ovid MEDLINE, CINAHL, and Web of Science databases for randomized controlled trials reporting event rates for a composite cardiovascular outcome of cardiovascular death, myocardial infarction, and stroke in patients with T2DM and CKD receiving GLP1-RA or placebo. Studies were restricted to those reporting specific event rates for patients with CKD separately from the overall population. We conducted a meta-analysis using a random-effects model. This meta-analysis was registered on PROSPERO (CRD42022320157). …

Dietary And Complementary Feeding Practices Of Us Infants, 6 To 12 Months: A Narrative Review Of The Federal Nutrition Monitoring Data, Regan L Bailey, Jaime S Stang, Teresa A Davis, Timothy S Naimi, Barbara O Schneeman, Kathryn G Dewey, Sharon M Donovan, Rachel Novotny, Ronald E Kleinman, Elsie M Taveras, Lydia Bazzano, Linda G Snetselaar, Janet De Jesus, Kellie O Casavale, Eve E Stoody, Joseph D Goldman, Alanna J Moshfegh, Donna G Rhodes, Kirsten A Herrick, Kristin Koegel, Cria G Perrine, Tusarebecca Pannucci

Children’s Nutrition Research Center Staff Publications

Complementary foods and beverages (CFBs) are key components of an infant’s diet in the second 6 months of life. This article summarizes nutrition and feeding practices examined by the 2020 Dietary Guidelines Advisory Committees during the CFB life stage. Breastfeeding initiation is high (84%), but exclusive breastfeeding at 6 months (26%) is below the Healthy People 2030 goal (42%). Most infants (51%) are introduced to CFBs sometime before 6 months. The primary mode of feeding (ie, human milk fed [HMF]; infant formula or mixed formula and human milk fed [FMF]) at the initiation of CFBs is associated with the timing …

Randomization, Design And Analysis For Interdependency In Aging Research: No Person Or Mouse Is An Island, Daniella E Chusyd, Steven N Austad, Stephanie L Dickinson, Keisuke Ejima, Gary L Gadbury, Lilian Golzarri-Arroyo, Richard J Holden, Yasaman Jamshidi-Naeini, Doug Landsittel, Tapan Mehta, J Michael Oakes, Arthur H Owora, Greg Pavela, Javier Rojo, Michael W Sandel, Daniel L Smith, Colby J Vorland, Pengcheng Xun, Roger Zoh, David B Allison

Children’s Nutrition Research Center Staff Publications

Investigators traditionally use randomized designs and corresponding analysis procedures to make causal inferences about the effects of interventions, assuming independence between an individual's outcome and treatment assignment and the outcomes of other individuals in the study. Often, such independence may not hold. We provide examples of interdependency in model organism studies and human trials and group effects in aging research and then discuss methodologic issues and solutions. We group methodologic issues as they pertain to (1) single-stage individually randomized trials; (2) cluster-randomized controlled trials; (3) pseudo-cluster-randomized trials; (4) individually randomized group treatment; and (5) two-stage randomized designs. Although we present …

Second-Best Free Exercise, Christopher C. Lund

Fordham Law Review

The future of the Free Exercise Clause is up in the air. Thirty years ago, in Employment Division v. Smith, the Supreme Court held the Free Exercise Clause only protected against religious discrimination and did not require exemptions from neutral and generally applicable laws.

Yet despite having an official rule against religious exemptions, the Roberts Court has somehow managed to give religious exemptions in case after case. This illustrates Smith’s waning power—the case has become more of an obstacle for courts to work around than a precedent for courts to obey. But these victories have also come to …

Arbitration And Finra's Customer Code: A Tailored Approach To When A Forum Selection Clause May Supersede Finra Rule 12200, Peter Giovine

Fordham Law Review

This Note examines a circuit split concerning whether forum selection clauses supersede Financial Industry Regulatory Authority (FINRA) Rule 12200, which requires FINRA members to arbitrate customer disputes upon the customer’s request. The U.S. Courts of Appeals for the Second and Ninth Circuits have upheld a waiver of the right to arbitrate even when arbitration is not explicitly mentioned in a forum selection clause. The U.S. Courts of Appeals for the Third and Fourth Circuits, on the other hand, have held that a forum selection clause that does not explicitly mention arbitration does not supersede FINRA Rule 12200. This Note explores …

Closing The Door On Permanent Incorrigibility: Juvenile Life Without Parole After Jones V. Mississippi, Juliet Liu

Fordham Law Review

In April 2021, the U.S. Supreme Court decided Jones v. Mississippi, its latest opinion in a line of cases addressing when, if ever, a child should be sentenced to life in prison with no hope of parole or release. Although Jones purported to resolve division among lower courts over the findings that a sentencing court must make about a child defendant’s character and prospects for reform and rehabilitation, the decision will likely lead to further disagreement among courts.

This Note argues that although the Supreme Court’s jurisprudence has protected children from harsh sentences, it has also opened a Pandora’s …

Assessment Design For Digital Education: An Analytics-Based Authentic Assessment Approach, Lim Ming Soon Tristan, Gottipati Swapna, Michelle L. F. Cheong, Christopher Pang, Jun Wei Ng

Research Collection School Of Computing and Information Systems

This study looks to identify an assessment design construct that overcomes known issues in authentic assessment design practices in digital education. These include lack of "freedom-of-choice", lack of focus on multimodal nature of the digital process, and shortage of effective feedbacks. This study proposes an authentic assessment, that combines gamification (G) with heutagogy (H) and multimodality (M) of assessments, building upon learning analytics (A), known as GHMA. Proposed assessment design is a skills-oriented game-based assessment approach. Learners can determine their own goals and create individualized multimodal artefacts; receive cognitive challenge through cognitively complex tasks structured in gamified non-linear learning paths; …

Learning Dynamic Multimodal Implicit And Explicit Networks For Multiple Financial Tasks, Meng Kiat Gary Ang, Ee-Peng Lim

Research Collection School Of Computing and Information Systems

Many financial f orecasting d eep l earning w orks focus on the single task of predicting stock returns for trading with unimodal numerical inputs. Investment and risk management however involves multiple financial t asks - f orecasts o f expected returns, risks and correlations of multiple stocks in portfolios, as well as important events affecting different stocks - to support decision making. Moreover, stock returns are influenced by large volumes of non-stationary time-series information from a variety of modalities and the propagation of such information across inter-company relationship networks. Such networks could be explicit - observed co-occurrences in online …

A Logistic Regression And Linear Programming Approach For Multi-Skill Staffing Optimization In Call Centers, Thuy Anh Ta, Tien Mai, Fabian Bastin, Pierre L'Ecuyer

Research Collection School Of Computing and Information Systems

We study a staffing optimization problem in multi-skill call centers. The objective is to minimize the total cost of agents under some quality of service (QoS) constraints. The key challenge lies in the fact that the QoS functions have no closed-form and need to be approximated by simulation. In this paper we propose a new way to approximate the QoS functions by logistic functions and design a new algorithm that combines logistic regression, cut generations and logistic-based local search to efficiently find good staffing solutions. We report computational results using examples up to 65 call types and 89 agent groups …

Towards Reinterpreting Neural Topic Models Via Composite Activations, Jia Peng Lim, Hady Wirawan Lauw

Research Collection School Of Computing and Information Systems

Most Neural Topic Models (NTM) use a variational auto-encoder framework producing K topics limited to the size of the encoder’s output. These topics are interpreted through the selection of the top activated words via the weights or reconstructed vector of the decoder that are directly connected to each neuron. In this paper, we present a model-free two-stage process to reinterpret NTM and derive further insights on the state of the trained model. Firstly, building on the original information from a trained NTM, we generate a pool of potential candidate “composite topics” by exploiting possible co-occurrences within the original set of …

The Language Of Recruitment: How Minority Status, Racial Minority Centrality, & Linguistic Cues Impact Applicant Perceptions, Clark Waters

Theses and Dissertations

As color-blindness, the intentional denial of racial differences, continues to occupy corporate policy, expressions and consequences of modern racism in the workplace remain pervasive. Color-blind attitudes can be harmful due to their focus on perceived equality, at the expense of actionable, functional equity. Establishing a culture of racial equity in the workplace requires an understanding of how the language used to discuss race can impact potential applicants’ opinions of the company. To attract a diverse pool of job applicants, the language of recruitment is of particular importance in the current study. Using a vignette-style survey design, a diverse sample of …

Analysis Of Proposed Active Radiation Shielding Design Concept For Spacecraft, Claire Mechmann

Theses and Dissertations

A need exists to protect the crew of interplanetary spacecraft from lethal doses of Galactic Cosmic Radiation (GCR) and Solar Energetic Particles (SEPs). As plans progress to send humans beyond lower Earth orbit (LEO) and outside of Earth’s protective magnetosphere, agencies involved in this endeavor find themselves confronted with the obstacle of shielding the crew from this harmful radiation. A proposed active shielding concept design has been suggested, utilizing charged dielectric capacitors to deflect incoming charged particles. This analysis will examine the feasibility of the proposed design and offer potential materials useful for application. The results should prove informative for …

Importance Of Light Activation For Plant Cryptochrome And Antibacterial Drug Delivery Strategies, Merfat Ahmed Hammad

Theses and Dissertations

The goal of this project is to investigate the benefits of applying light in different systems. In the first part, the magnetoreception process that occurs in the light activated cryptochrome of Arabidopsis Thaliana was investigated. In the second part, photo-carbon monoxide releasing molecules (photo-CORMs) were investigated for their antibacterial effect to develop biomedical strategies. Overall, this has been achieved in three different studies. The first study investigated if the forward lightdriven reaction is involved in the magnetoreception process or not in cryptochrome (CRY). To accomplish this, the plant seedlings were tested for 90 minutes as follows: 5 minutes in the …

Design And Optimization Of High-Power Density Permanent Magnet Motor With Integrated Cooling For Aircraft Propulsion, Aravindakshan Thirumalai Ananthanpillai

Theses and Dissertations

There is a critical need for the electrification of transportation systems. While power density required for ground-based vehicles can, to some extent, be met by current off-the-shelf motors and generators, aircrafts require significant improvements both in terms of power density and efficiency. The concept relies on the tight integration of a high-power density dual-rotor permanent magnet motor, high power density SiC power converters, and a shared closed loop cooling system rejecting the heat in the propulsion ducted fan air stream. The motor is based on a dual-rotor configuration using permanent magnets forming ideal Halbach arrays allowing for high magnetic loading …

Arts Marketing, David Ocon

Research Collection School of Social Sciences

Although there are hundreds of resources on traditional and commercial marketing, the materials available specifically for arts marketing are scarce, posing additional challenges for Gillian. Furthermore, while some focus on arts management, few of them address marketing from the perspective of a small-to-medium (often financially struggling) arts organization. An organization like Gillian’s often has limited resources, both financial and human, and can only approach marketing informally. However, it experiences the same pressures to perform well as larger arts institutions. Often, survival depends on how well it implements the marketing strategies that marketing staff create on their own. This chapter is …

Inactivation Kinetics Of Bacillus Atrophaeus In Liquid Hydrogen Peroxide For Aseptic Package Sterilization, Manoj Sawale, Xiang Cheng, Rishi Drolia, Patnarin Benyathiar, Ferhan Ozadali, Arun Bhunia, Dharmendra Mishra

EKU Faculty and Staff Scholarship

Liquid hydrogen peroxide is used as a common sterilant for the aseptic packaging materials. Based on the Food Safety Objective (FSO) for specific products, a surrogate organism, Bacillus atrophaeus, is used to validate the sterilization processes. This study aims to develop a methodology for the kinetic inactivation parameter estimation of B. atrophaeus. Spores of B. atrophaeus were challenged with various peroxide concentrations (20%, 28%, and 33%; v/v) and temperatures such as 23, 55, 71.1, and 82.2 °C. The log-linear and Weibull models were used for the inactivation models for liquid peroxide at different temperatures. The parameters …

Characterizing The Cutaneous Microbiome Of Eurycea Lucifuga As A Potential Defense Against Chytridiomycosis, Madeline Key

Senior Honors Theses

Chytridiomycosis is an emerging infectious disease that is significantly reducing global amphibian populations. The disease is caused by Batrachochytrium dendrobatidis (Bd), a fungus that lethally modifies amphibian skin. Recent research has suggested that the cutaneous microbiome of individual amphibians may play a role in susceptibility to the pathogen. In this study, twelve cave salamanders (Eurycea lucifuga) were collected. Cutaneous bacteria from each salamander were isolated and identified using Sanger Sequencing. Additionally, a Bd-challenge assay was performed to determine each isolate’s antifungal activity. Results indicated many microbial isolates possessed inhibitory capabilities against Bd, which may …

Peer Mentoring And Test Anxiety In Collegiate Aeronautics Students: An Integrative Review, Angelo R. Cosentino

Senior Honors Theses

An integrative review was conducted to lay the foundation for further research focusing on the use of peer mentoring as a tool to reduce the anxiety pilots and mechanics feel for their oral and practical exams to increase student safety and performance. Research on performance anxiety in competitive sports, music performance anxiety, and academic test anxiety showed how anxiety levels relate to athlete and student performance. Feedback surveys from peer mentoring programs identified increased self-efficacy, increased student retention, and a better understanding of the applicable examination as possible benefits of such mentoring programs. I determined the proposed research question was …

Worried Sick: Understanding The Implications Of Stress On A Physiological Level, Julia Saia

Senior Honors Theses

Stress is prevalent among many individuals in today’s society. A literature review was conducted to investigate the physiological effects of stress, including the biomarkers of stress and how these interact with various body systems. The stress response is a protective mechanism to prepare the body to adequately respond to a perceived threat. However, when this response is prolonged, it begins to have a maladaptive effect on the body and can cause more harm than good. This literature review sought to compile what is known regarding the general effects of chronic stress and its impact on the nervous, immune, digestive, and …