Digital Commons Network^™

Flying Hope: Bringing Pets To Safety In Nyc, Jose D. Santiago-Morales

Capstones

The animal overcrowding issue is impacting stray pets in Puerto Rico. Various not-for-profit organizations in NYC (The Sato Project and Wings of Rescue) are working to bring these animals from the island to states across the Northeast of the United States and helping by finding them their forever homes. One pet at a time.

https://dansantiagojournalist.wordpress.com/2023/10/01/flying-hope-bringing-pets-to-safety-in-nyc/

Grip Characterization Of Protective Gloves, Doris Burns

Theses & Dissertations

In 2014, ASTM International (ASTM), one of the world's largest international standards developing organizations, published a new test method on glove grip performance. This method was adopted by the National Fire Protection Association (NFPA) in some of their specification standards. The method utilized hand torque instead of the pull method previously used by the NFPA to determine the Percent Bare Hand Control Value (%BHCV). The %BHCV, compares torque results of a gloved hand versus a bare hand. In developing this new test method, only four males and one female participated; therefore, it is unclear if statistical significance was attained. In …

New York City Homeless Queer Youth Face Harsh Realities; Advocates Fight For Change, Randi R. Love

Capstones

New York City unhoused youth face years of harsh realities because the lack of knowledge and policies that exist to aid them don't provide the protections and outreach to assure they don't live on the streets or in bad situations for years to come. These youths experiences are exacerbated when sexuality or gender are included.

https://randilove.github.io/capstone-2022/

Unpure: Serving The Purity Culture Deconstruction Community, Julia Capizzi

Capstones

Unpure: Serving the Purity Culture Deconstruction Community is an in-depth understanding of how engagement journalism can serve those who are deconstructing, or unlearning, harmful religious beliefs around sex and sexuality.

The Science And Practice Of Coping With Pet Loss, Michayla Savitt

Capstones

Losing a pet can have a huge impact on a household - including humans and pets alike. This mixed multimedia project works to capture this multimedia project exploring how loss manifests in the home after a pet’s passing — and how we remember our pets after they’re gone. It’s done through short non-narrative documentaries from multiple pet owners, along with insight from a mental health expert, and animal behaviorists. I’ve incorporated research around pets having grief-like reactions to a companion animal, in addition to why grieving a pet is so painful, and how pet grief often doesn’t fit in with …

Eavesdropping On Animals: Can Bioacoustics Help Save Species?, Zoe Grueskin

Capstones

Around the world, scientists are using sound to study the natural world in a growing field called bioacoustics. Researchers are eavesdropping on frogs and fish, elephants and earthworms, and many hope what they hear can inform and inspire conservation action around the world. From the field’s auspicious beginning with accidentally-recorded whales, to researchers today listening to locations as diverse as the Arctic seafloor and India’s Western Ghats mountain range, this capstone project explores the potential — and limitations — of conservation bioacoustics. Read the story, see photos and listen to audio pieces featuring three bioacousticians and their field recordings here: …

Preservando La Playa Del Pueblo, Tasha A. Sandoval

Capstones

After more than 80 years, the only queer beach in New York City, the People’s Beach at Jacob Riis, is in danger. In 2022, the city announced the demolition of the Neponsit Hospital, a long-abandoned structure that shelters the beach from the street, creating a sense of privacy and safety. Can Riis Beach live on as a safe and joyous utopia for queer communities without the presence of the hospital buildings? Some beach-goers are campaigning to ensure that whatever replaces the hospital space centers the queer community and preserves the beach’s queer history, including the legacy of Ms. Colombia, a …

New York City’S Wage Theft Crisis, Amanda Rozon

Capstones

In New York City, all workers regardless of citizenship status are granted the same rights under New York State labor laws. But in the construction industry, undocumented immigrant workers who are reluctant to report violations are at risk of being exploited by their employers and often fall victim to wage theft. Despite efforts by the city and local immigrant rights organizations, wage theft remains high; according to a study by the Center For Popular Democracy, New Yorkers are cheated out of roughly $3 billion annually. https://medium.com/@amanda.rozon37/new-york-citys-wage-theft-crisis-9595917491ce

A Lifetime Of Heroin Addiction: Jose Hernandez's Story, Pumla Kalipa

Capstones

Jose Hernandez is a 55 year old Hispanic man who has been battling with heroin and other illicit-drug abuse for over 30 years. In this story we spend time with him to understand what his daily struggles are and how he uses heroin to cope with certain life stressors. This mini-documentary and short story is also meant to inform the public about substance abuse and how to get help if needed. https://pumlakalipa01.exposure.co/a-lifetime-of-heroin-addiction?source=share-pumlakalipa01

Secondhand Shopping Is Now The Coolest Way To Get Your Clothes, Camryn Quick

Capstones

Shopping secondhand has experienced an uptick in popularity in the past few years. There are a few reasons for this, all of which are examined in the project. One reason for the increase in secondhand shoppers is the daunting news about the state of our environment. Another reason, perhaps even more powerful than the fear of environmental collapse, is that thrifting has become a fashion phenomenon showcased and distributed throughout social media apps like TikTok. Essentially, shopping secondhand has become cool. This project explores these driving forces behind the thrifting boom, as well as the possible impacts, including "thrift store …

Wellness That Doesn’T Work. When Lifestyle Apps Lead To Disordered Eating., Aurelie G. Muntzel

Capstones

Fitness and dieting are nothing new, but what makes the latest generation of dieting apps that pair with smart watch devices which track your nutrition and biometric data so different is how much easier they can lead you towards disordered eating. This capstone explores how corporate incentives drive diet apps to co-opt the language of wellness discourse in order to attract the Gen Z market, while selling a product that equates healthiness to a number on a scale.

Decreasing Hospital Acquired Pneumonia In Adult Patients By Patient Care Technicians: Education With A Focus On Oral Care And Tooth Brushing, Amanda Nicole Lee

Master's Projects and Capstones

Hospital acquired pneumonia’s (HAPs) are unfortunate and preventable events quality improvement efforts should focus on. At a Northern California Hospital, there was an unmet HAP rate goal of 2.3 (20 out of 8795 patients) against a target goal of 2. This increase in HAP rates, both non-ventilated and ventilated was a call to action to reduce HAP to the target goal. The quality improvement project specifically aimed to reduce HAP rates on medical-surgical units through an ultra-brief refresher on the hospital validated and endorsed ROUTE bundle. The education focused on oral care completed by the patient care technicians (PCT’s). The …

Esp In Nursing: Building Communicative Competence For Internationally-Educated Nurses, Sami Vuong

Master's Projects and Capstones

The nursing shortage in the United States has been an ongoing issue due to nursing burnout and retirement. Together with the COVID-19 pandemic, it has further exhausted the healthcare system’s resources and healthcare providers. In order to sustain the healthcare system in society, a large number of internationally educated nurses (IENs) have been transferred to work in the United States. As a result of different nursing practices, cultures, and communication styles, many IENs experience language and cultural barriers at work. Difficulty in communication influences the quality of patient care provided, which can lead to negative health outcomes for patients and …

United States Pharmacopeia (Usp) <800> Standards: Increasing Compliance Of Safe Handling And Proper Administration Of Usp General Chapter <800> Drugs, Katelyn N. Sinclair

Master's Projects and Capstones

Problem: United States Pharmacopeia (USP) developed a set of standards to minimize exposure risks to patients, healthcare workers, and the environment when preparing, handling, and administering hazardous drugs (HDs) known as USP <800> HDs. The guidelines became effective December 1, 2019, but additional information is needed to ensure healthcare personnel are complying with the standards.

Context: Two medical surgical units from Hospital A were included in this project. Currently mandatory online modules about USP <800> standards are provided annually to every healthcare worker, but it is unknown if the policies and procedures are being followed appropriately.

Interventions: Active and passive observations as …

In Vivo Characterization Of Glutamine Metabolism Identifies Therapeutic Targets In Clear Cell Renal Cell Carcinoma, Akash K Kaushik, Amy Tarangelo, Lindsey K Boroughs, Mukundan Ragavan, Yuanyuan Zhang, Cheng-Yang Wu, Xiangyi Li, Kristen Ahumada, Jui-Chung Chiang, Vanina T Tcheuyap, Faeze Saatchi, Quyen N Do, Cissy Yong, Tracy Rosales, Christina Stevens, Aparna D Rao, Brandon Faubert, Panayotis Pachnis, Lauren G Zacharias, Hieu Vu, Feng Cai, Thomas P Mathews, Giannicola Genovese, Barbara S Slusher, Payal Kapur, Xiankai Sun, Matthew Merritt, James Brugarolas, Ralph J Deberardinis

Faculty, Staff and Student Publications

Targeting metabolic vulnerabilities has been proposed as a therapeutic strategy in renal cell carcinoma (RCC). Here, we analyzed the metabolism of patient-derived xenografts (tumorgrafts) from diverse subtypes of RCC. Tumorgrafts from VHL-mutant clear cell RCC (ccRCC) retained metabolic features of human ccRCC and engaged in oxidative and reductive glutamine metabolism. Genetic silencing of isocitrate dehydrogenase-1 or isocitrate dehydrogenase-2 impaired reductive labeling of tricarboxylic acid (TCA) cycle intermediates in vivo and suppressed growth of tumors generated from tumorgraft-derived cells. Glutaminase inhibition reduced the contribution of glutamine to the TCA cycle and resulted in modest suppression of tumorgraft growth. Infusions with …

Protocol For Mathematical Prediction Of Patient Response And Survival To Immune Checkpoint Inhibitor Immunotherapy, Joseph D Butner, Maguy Farhat, Vittorio Cristini, Caroline Chung, Zhihui Wang

Faculty, Staff and Student Publications

This protocol describes the application of a mechanistic mathematical model of immune checkpoint inhibitor (ICI) immunotherapy to patient tumor imaging data for predicting solid tumor response and patient survival under ICI intervention. We describe steps for data collection and processing, data pipelines, and approaches to increase precision. The protocol is highly predictive as early as the first restaging after treatment start and can be used with standard-of-care imaging measures. For complete details on the use and execution of this protocol, please refer to Butner et al. (2020)

Processing And Cryopreservation Of Human Ureter Tissues For Single-Cell And Spatial Transcriptomics Assays, Emily E Fink, Surbhi Sona, Byron H Lee, Angela H Ting

Faculty, Staff and Student Publications

Characterizing the cellular heterogeneity of human ureter tissues using single-cell RNA sequencing (scRNA-seq) and spatial transcriptomics provides a detailed atlas of cell types, signaling networks, and potential cell-cell cross talk underlying developmental and regenerative pathways. We describe an optimized protocol for generating, cryopreserving, and thawing single-cell suspensions from ureter tissues isolated post-cystectomy for scRNA-seq. In addition, we describe an optimized protocol for cryopreserving human ureter tissues for 10x Genomics Visium spatial gene expression platform. For complete details on the use and execution of this protocol, please refer to Fink et al. (2022).

Isolation, Culture, And Immunophenotypic Analysis Of Bone Marrow Hspcs From Patients With Myelodysplastic Syndromes, Irene Ganan-Gomez, Karen Clise-Dwyer, Simona Colla

Faculty, Staff and Student Publications

Drug testing assays in hematopoietic stem and progenitor cells (HSPCs) are fundamental in biological studies of myelodysplastic syndromes (MDS) but have historically entailed a technical challenge. This protocol allows the efficient isolation of MDS HSPCs from bone marrow mononuclear cell fractions and their culturing with the support of stromal cells for improved maintenance during drug testing. Lastly, specific steps are given to quantify surviving cells and assess changes in the HSPC hierarchies.

For complete details on the use and execution of this protocol, please refer to Ganan-Gomez et al. (2022).

Warren B. Davis And The Birth Of Plastic Surgery In Philadelphia: A Historical Vignette, Sarah F. Wagoner, Charles J. Yeo, Renee M. Tholey, James W. Fox, Steven E. Copit

Department of Surgery Faculty Papers

The field of plastic surgery, formally organized in 1931 with the founding of the American Society of Plastic and Reconstructive Surgery, was shaped in many ways by a small practice of Philadelphia physicians. At the center of the practice was Warren B. Davis, a Philadelphia otolaryngologist and plastics pioneer whose innovations in cleft palate surgery would lead to significant improvements in functional and cosmetic outcomes in his time. In addition to his own innovations, Davis was responsible for the training of John Reese, the inventor of the Reese dermatome that changed the face of burn medicine during World War II. …

The Impact Of Habitual Dietary Fat Intake On Postprandial Lipemia In Older Adults, Sophia A. Bollinger

Masters Theses, 2020-current

Postprandial lipemia (PPL) is a risk factor for cardiovascular disease (CVD). Many older Americans experience elevated PPL due to a chronically high-fat diet and an inefficient ability to clear triglycerides (TG) from circulation. TG levels are typically measured in a fasted state; however, postprandial TG levels may be more strongly associated with CVD risk. This study grouped ten older adults into two dietary consumption fat categories and examined the response to an acute high-fat meal by measuring postprandial blood cholesterol, TG, and glucose (GLU) at baseline, 30-minutes post-meal, 60 minutes, 90 minutes, 120 minutes, 180 minutes, and 240 minutes. Participants …

Sunsetting Excessive Chest X-Rays In An Intensive Care Unit: A Quality Improvement Project, Cassandra Sweet

Doctors of Nursing Practice (DNP) Final Projects, 2020-current

In the cardiovascular service line at an academic medical center in the southeastern United States, obtaining daily chest x-rays still occurred despite evidence that it is unnecessary and possibly even harmful. This quality improvement project was implemented in a 24-bed Cardiovascular Intensive Care Unit and 20-bed acute care unit, together considered to be the cardiac service line. Using the implementation framework of the Model for Improvement and Plan/Do/Study/Act, a guideline that outlines appropriate times to obtain a chest x-ray based on the American College of Radiology’s appropriateness criteria was created. Daily chest x-rays were eliminated and replaced with an on-demand …

Postoperative Atrial Fibrillation Prevention: A Quality Improvement Project, Emily O. Schneiderman

Doctors of Nursing Practice (DNP) Final Projects, 2020-current

Postoperative atrial fibrillation remains one of the most common complications after cardiac surgery despite surgical and medical advances in the field. While generally transient, postoperative atrial fibrillation increases long-term morbidity and mortality, hospital length of stay, and financial obligation. The postoperative heart's unique chemical and physical properties make tactics for preventing and treating postoperative atrial fibrillation differ from classic atrial fibrillation management. This quality improvement project utilizes a care bundle for non-pharmacologic measures and early beta-blockade administration to reduce the incidence of postoperative atrial fibrillation. Implementation of this care bundle establishes a standard of care, increases clinician knowledge and accountability, …

Implementing Routine Depression Screening In An Urgent Care Setting: An Implementation Science Project, Lori Conyers

Doctors of Nursing Practice (DNP) Final Projects, 2020-current

Identifying patients with depression is essential, and early detection of depression leads to early intervention. Routine screening of patients for depression is the responsibility of the primary care provider, but many patients have not had a primary care visit in the recent past. Those patients without a primary care provider are likely not being screened for depression. Urgent care (UC) may be the best opportunity to screen patients who do not have a medical home. However, the dynamic nature of the urgent care setting may dissuade staff from engaging in routine screening. As a quality improvement (QI) effort, regular PHQ …

Medication Reconciliation Policy Analysis: A Collaborative Project With The Principal Hospital In Cayman Islands Health System, Bethany Landes

Doctors of Nursing Practice (DNP) Final Projects, 2020-current

Medication errors, readmissions, and chronic disease management complications are modifiable healthcare problems. Standardized Medication Reconciliation (Med Rec) policies can impact healthcare organizations' patient safety by reducing these medication errors, decreasing readmission rates, enhance the management of chronic disease while also offering fiscal stewardship for healthcare systems. Medication management standardized policies are an expectation of systems aiming to gain Joint Commission (JC) accreditation. The principal hospital of the Cayman Islands does not have a medication reconciliation policy. Using The Eightfold Path to More Effective Problem Solving, multiple policy options that offer evidence-based recommendations were reviewed for consideration of a standardized Med …

Developing Influential Nurse Leaders: Utilizing Strengths And Styles Assessments To Create Individualized, Intentional Coaching, Linda Shepherd

Doctors of Nursing Practice (DNP) Final Projects, 2020-current

Abstract

Background: A north-central Virginia university and a hospital in the British West Indies (BWI) entered a collaborative agreement in 2020. Growing competitive environments heightened awareness and urgency in creating expansively competent, influential nurse leaders in the BWI. Without formalized data to quantify or validate nurse manager strengths, leadership style, or competencies, an assessment of these items and an evidence-based coaching intervention were performed.

Methods: The population for this evidence-based (EB) practice project was 20 inpatient nurse leaders. The Multifactor Leadership Questionnaire (MLQ) and the Clifton Strength Finders Assessment (CSF) for Managers were deployed as pre-intervention assessment tools. …

Formal Caregiver Burden Among Nursing Assistants In Nursing Homes: A Mixed Methods Study, Rachel Kunkle

Theses & Dissertations

Formal caregivers are the direct care workforce in nursing homes that aid residents. Providing care to residents is hazardous and demanding, as highlighted during the pandemic. Caregiver burden affects formal caregivers; however, is interchanged with caregiver stress and caregiver burnout. The overall purpose of this dissertation was to describe formal caregiver burden among nursing assistants who provide direct care to residents in nursing homes. This was first accomplished by conducting a concept analysis of formal caregiver burden in nursing homes. Next, an integrative review of the literature was performed to assess formal caregiver burden in nursing homes and available psychometric …

How Much Should Or Can Science Impact Theological Formulations? An AshʿArī Perspective On Theology Of Nature, Shoaib Ahmed Malik, Nazif Muhtaroglu

All Works

There have been many developments in the field of science and religion over the past few decades. One such development is referred to as ‘theology of nature’ (ToN), which is the activity of building or revising theological frameworks in light of cont...

Variation In The M-Opioid Receptor (Oprm1) And Offspring Sex Are Associated With Maternal Behavior In Rhesus Macaques (Macaca Mulatta), Zachary Baron

Theses and Dissertations

A m-opioid receptor (OPRM1) single-nucleotide-polymorphism, found in both humans and rhesus macaques mediates the mother-infant attachment bond. Because mothers treat their sons and daughters differently, it is somewhat surprising that the role of infant sex has not been assessed in the context of a maternal-OPRM1-genotype-by-infant-sex interaction. The present study investigates the effect of maternal-OPRM1-genotype and infant sex on mother-infant behaviors. Over the first six months of offspring life, mother-infant behavioral data assessing attachment quality was collected twice weekly from a large number of rhesus monkey mother-infant pairs (N=161 dyads; n=64 female infants, n=97 male infants). Mothers were genotyped for OPRM1 …

Use Of Library Information Resources By Undergraduate Students At Sokoine University Of Agriculture, Tanzania, Nicholaus Mwalukasa Dr

Library Philosophy and Practice (e-journal)

The study examines use of library information resources by students of Sokoine University of Agriculture in Tanzania. The study employed cross-sectional research. Systematic sampling was to select 120 respondents. Data was collected using structured questionnaire. Quantitative data was coded and analyzed using the statistical package for social science (SPSS). Frequency and percentages was analyzed. The results found that most of the respondents mainly used special collection, general collection and special reserve. The study further found that e journal and e-book were the most accessed and utilized e resources, while dissertation was the least used e resources. The study also revealed …

Polymeric Chloroquine In Metastatic Pancreatic Cancer Therapy, Rubayat Islam Khan

Theses & Dissertations

Hydroxychloroquine (HCQ) is an established drug that has been used for the treatment of multiple diseases, including malaria, rheumatoid arthritis, and lupus erythematosus. Several recently published studies have highlighted its beneficial use in various types of cancers, and a plethora of clinical trials are currently evaluating its use in cancer therapies, wherein some of the results look promising. The preclinical studies to date suggest HCQ can work effectively in conjunction with traditional cancer treatments, as it has been shown to sensitize tumor cells to a wide range of chemotherapeutic agents. Polymeric HCQ (PCQ), a macromolecular multivalent version of HCQ, has …