Digital Commons Network^™

Estropause, Sex Hormones And Metal Homeostasis In The Mouse Brain, Tianbing Liu, Richard L. Bowen, Andrea C. Wilson, Craig S. Atwood

Research outputs 2022 to 2026

Alterations in brain metal ion homeostasis have been reported with aging and are implicated in the pathogenesis of neurodegenerative diseases. To assess whether age-related changes in hypothalamic-pituitary-gonadal (HPG) hormones might be involved in modulating brain metal ion homeostasis, we treated 7.5-month intact, sham-ovariecomized and ovariectomized C57B6SJL mice with vehicle or leuprolide acetate (for 9-months) to differentiate between whether sex steroids or gonadotropins might modulate brain metal ion concentrations. Unlike other aging mammals, there was no increase in plasma luteinizing hormone (LH) and follicle-stimulating hormone (FSH) concentrations following estropause in mice, suggesting there was sufficient residual production by the follicle depleted …

Burned Out And Unappreciated: Exploring Emotional Support For Certified Nursing Assistants In Skilled Nursing Facilities, Andrea H. Miller

Masters Theses

This qualitative exploratory study involved individual interviews with three certified nursing assistants (CNAs) working for skilled nursing facilities within the West Michigan area. Using semi-structured questions, the researcher asked the CNAs about the different critical incidents (CIs) and job demands they experience. CNAs were also asked about the support resources they currently have through their SNF employer, if those resources are meeting their needs, and if CISM could be a beneficial resource option. Thematic analysis was used to code and interpret the data from the interview to find four main themes: Burnout, Communication, Inconsistency, and Teamwork. Participants identified physical and …

Implementation Of Delirium Bundle On A Hospital Medical/Surgical Unit To Help Decrease The Prevalence Of Delirium, Sanusi Mohammed

Doctor of Nursing Practice Scholarly Projects

Description of the Problem: Delirium is defined as a constellation of symptoms that includes disturbance in attention or awareness, change in cognition, language and perceptual disturbances that develops over a short period of time. Delirium mostly affects adult patients with risk factors including history of dementia, early cognitive impairment, dehydration, and infections. This quality improvement project was implemented on one hospital unit at a large tertiary hospital in the Boston area. This unit has one highest rate of delirium in the entire hospital system. Delirium is associated with high rate of morbidity and mortality. Also, this syndrome leads to longer …

Transitioning Eating Practices Of Older Adults, Michelle Lajoy Jackson

Dissertations

Purpose: The purpose of this descriptive qualitative study was to explore what factors may have influenced the transition of an individual older adult’s eating practices over a lifespan and the impact participants perceived those factors currently had upon their nutritional health in older adulthood.

Background: The older adult population is recognized as one of the fastest growing populations in the United States. One of many growing concerns for this population is the impact of dietary practices on the morbidity and mortality of this aging population. There is limited research to date that has explored the transitioning of appetite …

Barriers To Exercise And Physical Activity - Insight From The Rural Practitioner, Erin G. Tillery

Honors College Theses

Sedentary lifestyles are a growing public health concern. Furthermore, many rural Americans lack adequate access to healthcare resources. When healthcare is sought, the patient-practitioner interactions may serve to influence the patient’s lifestyle choices. The practitioners' exercise and physical activity habits may shape the effectiveness of the patient-practitioners interaction. Here, we explored the potential barriers to exercise and physical activity (PA) in licensed physical and occupational therapists. In addition, we aimed to describe barriers to exercise and PA in individuals with a history of stroke from the perspective of the practitioner. Lastly, how current exercise and physical activity habits influence their …

The Impact Of Parenting Classes On Incarcerated Mothers, Kimberly D. Phillips Dr., Kyong-Ah Kwon

Journal of Prison Education and Reentry (2014-2023)

With growing public attention to the problem of mass incarceration, many individuals want to know about the vast rise in women’s incarceration rate; particularly concerning, the increase of mothers in prison. For many mothers, the only source of hope and motivation they have while involved in the criminal justice system is the connection with their children. This article demonstrates that educational programs focusing on parenting can help incarcerated mothers renew their parental role upon release from prison. The target audience for this article includes, but is not limited to, correctional facility administrators, family counselors, educators, and anyone with an interest …

Wake Tech And Gardner-Webb University Officials Announce New Transfer Partnership, Office Of University Communications

Gardner-Webb NewsCenter Archive

In a special online ceremony, Wake Tech Community College and Gardner-Webb University signed multiple articulation agreements making it possible for Wake Tech students who earn one of 10 Associate in Applied Science (AAS) degrees to complete a Bachelor of Science degree online with Gardner-Webb.

Gardner-Webb Alumnus Received Friendship, Opportunities And Support To Manage Autism And Accomplish His Goals, Office Of University Communications

Gardner-Webb NewsCenter Archive

With the education and opportunities he received at Gardner-Webb University, alumnus, Will Braunlich, ’20, does what he loves. He is the host of a movie review show that airs on the local cable TV in Simsbury, Conn., and on YouTube. He also recently started a job as a paraprofessional in the special education department at the local middle school.

Transformative Partnerships: Expanding Extension’S Capacity To Support Texans With Developmental Disabilities, Andrew B. Crocker, Morgan D. Bradley, Shelby D. Vaughn, Beth Stalvey

Journal of Extension

New partnerships to reach new audiences are key to Extension’s future (Harder, 2019). But partnership is enhanced through shared decision-making, co-creation of content, and leveraging non-overlapping expertise and experience (Bertsch et al., 2020; Israilov & Cho, 2017; Ostrom, 1996). Texas A&M AgriLife Extension Service partnering with the Texas Council for Developmental Disabilities provides a novel approach to using statewide presence to the benefit of a partner seeking to expand its footprint (Alford, 2014; Ostrom, 1996) and is, itself, an outcome (Voorberg et al., 2015). Additionally, Texans with disabilities benefit through greater access to the education and resources the partnership produces.

The Effects Of Astrocytic Derived Insulin-Like Growth Factor (Igf-1) On Cognition And Astrocytes, Destiny Wilson

Honors Theses

Insulin-like growth factor 1 (IGF-1) is a neuroendocrine signaling hormone that plays a vital role in growth and development, as well as learning and memory. Inhibition of this hormone results in cognitive impairments like those seen with age-related decline. While a majority of research has focused on the role of IGF-1 on neurons, the role of astrocytes still needs to be explored. Our research investigates how astrocytes and cognition are affected as a result of direct regulation of localized IGF-1 production in early development and after puberty. Preliminary studies in our laboratory established a connection between IGF-1 and glial fibrillary …

Investigating The Neuroprotective Effects Of Cannabinoids And Insulin-Like Growth Factors On Glia With Induced Inflammation, Caleb Bloodworth

Honors Theses

Chronic inflammation is a driver of numerous neurodegenerative diseases that reduce quality of life for affected individuals. Non-psychoactive cannabinoids have begun to gain more interest in the world of anti-inflammatory medicine for chronically ill patients. Along with these cannabinoids, insulin-like growth factor-1 has been examined for its association with downregulation of inflammation. Our research aimed to investigate how neuroglia are affected by treatment with cannabinoids or IGF-1 in the face of inflammation from HIV-1 protein, Tat, or lipopolysaccharide (LPS). Preliminary studies in our laboratory showed that neither cannabinoids or IGF-1 treatment altered astrocyte morphology or overall astrocyte viability under baseline …

Impacts Of Diabetes Stigma On Acute Healthcare Engagement Among Adults With Type 2 Diabetes, Kate Camillo

Honors Theses

Introduction: Individuals frequently experience public and self-stigma stemming from type 2 diabetes. Prior studies have linked stigma with higher levels of poorer diabetes outcomes such as greater disease-related distress and worse glycemic control. However, few if any studies have examined the association between diabetes-related stigma and healthcare utilization. This gap in the literature is critically important given the importance of proactive disease management and preventive care as well the high costs of acute service use in this population. Therefore, the purpose of the present study was to examine the relationship between type 2 diabetes stigma, patient activation, and acute medical …

An Exploratory Look Into The Effects Of Mississippi's Population Decline On Rural Dental Care, Allen Bailey Saffold

Honors Theses

Literature reviews and interviews with dentists working in rural Mississippi counties examined the effects of population decline on rural dental care in Mississippi. With the state’s continual population decline, loss of industry follows a loss of people. Through a cascade of effects, this can further reduce underserved areas’ access to dental care. In order to address the issue of rural Mississippi continuing to be underserved, policies need to be implemented that will make rural practice at least enticing if not desirable.

Finding Resilience Through Research: Completing A Ph.D. While Parenting An Intellectually Disabled Adult “Child”, Lorraine M. Hutton

The Qualitative Report

Unlike the progression of most traditional-aged, college or university students, my non-traditional, academic trajectory as a parent-caregiver to an intellectually disabled (ID) adult has been fraught with barriers, disruption, and discouragement. Motivation to complete my doctorate rests on a commitment to disability issues, caregiver activism, and intellectual capacity-building of my self. Guided by the “evocative” autoethnographic methodology of Bochner and Ellis (2016), this “insider’s” narrative retrospective autoethnography will attempt to shed light on and evoke an understanding of a doctoral student caregiver’s context and experience in the academy. It encompasses embodiment, a geographically constrained sense of place, marginalization, and neoliberal …

Ageism, Eldercare, And Healthcare: An Examination Of Growing Old In Costa Rica, Akshaya Vijayasankar

Honors Theses

The world’s aging population and the Covid-19 pandemic have revealed the high level of ageism against older adults around the globe, which has resulted in an overall decreased quality of life for elders. Societies are now faced with the challenge of creating a suitable and equitable model of care to support their aging population. Despite the recent publication of the World Health Organization's Global Report on Ageism, there is still a large gap in the literature regarding ageism. This paper addresses the issues of institutional ageism in the eldercare and healthcare sector. I argue that Costa Rica serves as a …

A Look Towards The Future Of Eldercare: Lessons Learned From Social Care Models In Japan, Caroline M. Steil

Honors Theses

The rapidly accelerating trend of population aging is redefining the state of eldercare globally, as every country is currently or will soon face a gap in the excess demand for care versus the scarce supply of caregivers, both formal and informal. Specifically, there is a decrease in the number of elders seeking care through a family member as well as less caregivers in institutions to provide care for elders. Japan is at the vanguard of this caregiving gap, and thus provides key lessons, particularly from two innovative models of eldercare: Ibasho, a grass-roots, non-profit organization, and Japan's Long-Term Care Insurance …

Planning For An Aging Population: The Sustainability Conundrum, Sandi Rosenbloom

Journal of Comparative Urban Law and Policy

By 2030 more than one in four Americans will be 65 years of age or older. What role do city planning academics and practitioners play in planning for the inevitable and increasing aging of society? I examined original research and reviewed articles published in three major planning journals, reviewed the websites of ten Planning Accreditation Board (PAB) accredited planning programs, and evaluated the websites of the American Planning Association’s divisions and special interest groups to determine how each demonstrated or portrayed the value and importance of aging issues in planning scholarship, pedagogy, and practice. I found that these key pillars …

2022 Spring Order Of Exercises Commencement: Winona State University, Winona State University

WSU Commencement Programs

This is the Winona State University Spring 2022 Order of Exercises booklet published for the commencement ceremony on Friday, May 6, 2022.

Implementation And Evaluation Of An End-Of-Life Standardized Participant Simulation Into An Adult/Gerontology Acute Care Nurse Practitioner Program, Shannon Daly

Doctor of Nursing Practice (DNP) Translational and Clinical Research Projects

Palliative care interventions are in high demand due to patients living longer with chronic, life-limiting conditions. Nursing professionals are instrumental in the care of patients across their lifespan, and it is imperative that they receive end-of-life care training in their respective curriculums. The aims of this project were to 1) implement end-of-life content into an AGACNP program using the ELNEC curriculum and 2) to determine if the simulated environment affects the AGACNP students’ self-confidence and anxiety levels when making clinical decisions for end-of-life patients. As a result of the standardized participant (SP) end-of-life simulation, AGACNP students experienced an increase in …

2022 Spring Commencement Program: Winona State University, Winona State University

WSU Commencement Programs

This is the Winona State University Spring 2022 commencement program. Commencement was on Friday, May 6, 2022.

Factors Associated With Advance Care Planning Engagement In Healthy Young Adults, Pablo J. Vasquez

Dissertations and Theses (Open Access)

Background: Advance care planning (ACP) is a process that supports individuals at any stage of health in understanding and sharing their personal values and goals pertaining current or future medical needs with their families and healthcare providers. Although ACP is applicable to adults of any age and any stage of the health continuum, it is widely associated with older or terminally ill populations, and the need for end-of-life (EOL) planning in healthy young adults is generally found unnecessary. The National Institutes of Health supports the expansion of ACP research in understudied populations. Investigating ACP in healthy young adults support such …

Conducting A Root Cause Analysis To Improve Intake Processes And Record Review In Home Health, Christina Guerrero

Doctor of Nursing Practice Projects

Minimization of adverse events, reduction of inpatient admissions, and prevention of polypharmacy within home health are of importance due to the increasing number of Medicare beneficiaries. In 2019, CMS reported 5,266,931 patients were served by home health agencies, accounting for 7,439,849 episodes of care. It is projected that the number of beneficiaries will rise from 54 million to more than 80 million by the year 2030. Medical errors are now the third-leading cause of death in the United States, surpassing diabetes, Alzheimer’s, and stroke. The Agency for Healthcare Research and Quality identifies a lack of institutional intake processes as the …

Telemedicine Across Borders: Entrenched Issues Exposed By Covid-19, Richmond B. Wrinkle

Georgia Journal of International & Comparative Law

No abstract provided.

Savoring And The Experiential Advantage: Savoring Beliefs Determine Consumer Happiness From Experiential Versus Material Purchases, Charlene Chu

Business Faculty Articles and Research

Consumer research finds that people derive greater enduring happiness from discretionary spending on experiential purchases (events that they personally encounter or live through) than material purchases (tangible objects that can be obtained and kept in their possession). While research in this area has contributed to our understanding of this “experiential advantage” by examining the underlying psychology of this phenomenon, individual differences in the experiential advantage have received less attention. The present investigation examines whether individual differences in savoring capacity affect the subjective well-being that consumers derive from experiential vs. material purchases. This research finds that the self-rated ability to savor …

Growth Hormone Signaling Shapes The Impact Of Environmental Temperature On Transcriptomic Profile Of Different Adipose Tissue Depots In Male Mice., Augusto Schneider, Berta Victoria, Maria Isabel Schiavon Cousen, Yimin Fang, Samuel Mcfadden, Justin Darcy, Adam Gesing, Erin R Hascup, Kevin N Hascup, Andrzej Bartke, Michal M Masternak

Articles

Growth hormone receptor knockout (GHRKO) mice are smaller, long living, and have an increased metabolic rate compared with normal (N) littermates. However, it is known that thermoneutral conditions (30-32°C) elicit metabolic adaptations in mice, increasing the metabolic rate. Therefore, we hypothesized that environmental temperature would affect the expression profile of different adipose tissue depots in GHRKO mice. For this, N (n = 12) and GHRKO (n = 11) male mice were maintained at 23 or 30°C from weaning until 11 months of age. RNA sequencing from adipose tissue depots (epididymal-eWAT, perirenal-pWAT, subcutaneous-sWAT, and brown fat-BAT) was performed. Thermoneutrality increased body …

Growth Hormone Signaling Shapes The Impact Of Environmental Temperature On Transcriptomic Profile Of Different Adipose Tissue Depots In Male Mice., Augusto Schneider, Berta Victoria, Maria Isabel Schiavon Cousen, Yimin Fang, Samuel Mcfadden, Justin Darcy, Adam Gesing, Erin R Hascup, Kevin N Hascup, Andrzej Bartke, Michal M Masternak

Articles

Growth hormone receptor knockout (GHRKO) mice are smaller, long living, and have an increased metabolic rate compared with normal (N) littermates. However, it is known that thermoneutral conditions (30-32°C) elicit metabolic adaptations in mice, increasing the metabolic rate. Therefore, we hypothesized that environmental temperature would affect the expression profile of different adipose tissue depots in GHRKO mice. For this, N (n = 12) and GHRKO (n = 11) male mice were maintained at 23 or 30°C from weaning until 11 months of age. RNA sequencing from adipose tissue depots (epididymal-eWAT, perirenal-pWAT, subcutaneous-sWAT, and brown fat-BAT) was performed. Thermoneutrality increased body …

A Preliminary Report: The Hippocampus And Surrounding Temporal Cortex Of Patients With Schizophrenia Have Impaired Blood-Brain Barrier, Eric L. Goldwaser, Randel L. Swanson, Edgardo J. Arroyo, Venkat Venkataraman, Mary C. Kosciuk, Robert G. Nagele, L. Elliot Hong, Nimish K. Acharya

Rowan-Virtua Research Day

Schizophrenia (SZ) is one of the most severe forms of mental illness, yet mechanisms remain unclear. A widely established brain finding in SZ is hippocampal atrophy, and a coherent explanation similarly is lacking. Epidemiological evidence suggests increased cerebrovascular and cardiovascular complications in SZ independent of lifestyle and medication, pointing to disease-specific pathology. Endothelial cell contributions to blood-brain barrier (BBB) compromise may influence neurovascular unit and peripheral vascular function, and we hypothesize that downstream functional and structural abnormalities may be explained by impaired BBB.

The Brodmann Area 39/40 Of The Brain In Alzheimer’S, Mild Cognitive Impairment, And No Cognitive Impairment Subjects At Advanced Age Demonstrate Comparable Levels Of Blood-Brain Barrier Breach, Dhara Rana, Forum Mangrola, Randel L. Swanson, Venkat Venkataraman, David A. Bennett, Zoe Arvanitakis, David Libon, Robert Nagele, Nimish Acharya

Rowan-Virtua Research Day

• Alzheimer’s disease (AD) is one of the most common form of dementia

• Mild cognitive impairment (MCI), specifically amnestic subtype, more likely to progress to AD

• Pathogenesis Theories:

• o Accumulation of amyloid-beta peptides and neurofibrillary tangles containing hyperphosphorylated neuronal tau protein
• o Blood Brain Barrier (BBB) dysfunction is associated with AD pathogenesis

• Brodmann area 39/40: regions of parietal cortex are responsible for language, spatial cognition, memory retrieval, attention, phonological processing, and emotional processing

• Hypothesis: An increased BBB permeability in Brodmann area 39/40 of AD and age-matched MCI and no cognitive impairment (NCI) subjects

Racial Disparity In Health Insurance Acquisition In The State Of California, Florence Jill Polina

Theses

Racial disparity continues to be a struggle in America. The main purpose of this project was to determine whether there is a relationship between race and the acquisition of health insurance in adult residents of California who are younger than 65 years old. Through secondary data gathering, analysis of an existing racial disparity in health care insurance acquisition was accomplished. The results of the project indicate that a relationship exists between race and health insurance acquisition, thereby promoting an opportunity to determine hindering factors and discuss recommendations that can help to alleviate them.

Exploring The Effects Of A Nurse Mentorship Program On Career Satisfaction And Retention, Jennifer Smith

DNP and Student Works

Global statistics have shown there is a major nursing shortage. It is imperative to stabilize the nursing workforce as the healthcare continuum continues to grow. Nurse career satisfaction is related to nurses' overall intent to stay. Newly licensed registered nurses are leaving healthcare settings at disturbing rates. With the increased need and the current shortages, the nursing profession is unequipped to meet the needs of the growing population. The purpose of this project is to increase nurse career satisfaction and intent to stay with the organization through the implementation of a nurse mentorship program for newly licensed registered nurses with …