Digital Commons Network^™

Skillman Avenue Church Of Christ (Dallas, Tx) Records, 1970-2010, Skillman Avenue Church Of Christ

Center for Restoration Studies Archives, Manuscripts and Personal Papers Finding Aids

No abstract provided.

Stabilized Core Gene And Pathway Election Uncovers Pan-Cancer Shared Pathways And A Cancer-Specific Driver, Pathum Kossinna, Weijia Cai, Xuewen Lu, Carrie S Shemanko, Qingrun Zhang

Department of Cancer Biology Faculty Papers

Approaches systematically characterizing interactions via transcriptomic data usually follow two systems: (i) coexpression network analyses focusing on correlations between genes and (ii) linear regressions (usually regularized) to select multiple genes jointly. Both suffer from the problem of stability: A slight change of parameterization or dataset could lead to marked alterations of outcomes. Here, we propose Stabilized COre gene and Pathway Election (SCOPE), a tool integrating bootstrapped least absolute shrinkage and selection operator and coexpression analysis, leading to robust outcomes insensitive to variations in data. By applying SCOPE to six cancer expression datasets (BRCA, COAD, KIRC, LUAD, PRAD, and THCA) in …

Composition Portfolio, Sourena Sefati

Music ETDs

I have selected six works I composed during my master’s program at UNM from 2020 to 2022. My String Trio, "The Fall," is one of the first works I wrote and recorded in 2020, as my experience with using some modal, tonal, and post-tonal elements employs some non-traditional techniques. The vocal piece "Human Beings" was my experience using Farsi and English texts and employing modal and post-tonal elements. The next work is "The Secrets Eternal" for Baritone (voice), Trumpet, Trombone, and bass Clarinet, which is recorded in early 2022. "The Forest" is my first electroacoustic piece employing some Persian instruments …

Gardner-Webb Officials Name New Dean Of The College Of Arts And Sciences, Office Of University Communications

Gardner-Webb NewsCenter Archive

Officials at Gardner-Webb University have named Dr. Robert G. Prickett as the new dean of the College of Arts & Sciences. Prickett previously served as associate dean of the College of Arts & Sciences at Winthrop University in Rock Hill, S.C., a position he’s held for seven years. Prickett has worked at Winthrop in various administrative and teaching roles since 2010.

The Feminization Of Mexico City In The Late Twentieth Century: Polvo De Gallina Negra, Pola Weiss, And Lourdes Grobet, Alexis N. Corral

Theses and Dissertations

This thesis centers on select artworks in public intervention, photography and video as an exploration of female's relationship to Mexico City's social landscape and urban space during the late 1970s into the early 1990s. In three case studies, I explore historical urban planning, gender relations, and the effects of modernization.

Effects Of The Form Of Address “You Guys”, Jocelyn Sawyer

Theses and Dissertations

Renewed focus on workplace inclusivity has prompted calls to eliminate the mixed-gender group address “you guys” due to its potential to lower women’s sense of belonging. Our study found that interactions between this address and participant gender affected opinions on gender inequality but did not affect women’s sense of belonging.

Exploring Relationships Between Dog Training Approaches And Aggression, Fear, And Dog-Owner Relationship, Janee Wise

Theses and Dissertations

Abstract

The current study examined relationships between operant conditioning derived dog training techniques and aggression, fear, and dog-owner relationship. Participants (N = 326) completed two online surveys; 1) a survey created for this study measuring the frequency of use of 14 common dog training techniques, which were grouped into four categories based upon operant conditioning: positive reinforcement, negative punishment, positive punishment, and negative reinforcement and 2) the Canine Behavioral Assessment and Research Questionnaire (C-BARQ), which measured several factors related to dog behavior. There were no statistically significant results related to the use of positive reinforcement or positive punishment. However, dog …

Nikki S. Lee’S Self-Stereotyping And Refiguring Cultural Stereotypes, Somi Lee

Theses and Dissertations

This thesis examines a Korean Conceptual photographer, Nikki S. Lee’s performative photographs and film in the series of Projects (1998-2001) and Parts (2002-2005). Through a theoretical analysis of her self-representation in disguise, my research explores established Western stereotypes as well as the artist’s fluid identity in relation to other cultures.

An Epic (Fail): Humor, Play, And Politics In Chilean Contemporary Art From The Early 1980s, Paula Solimano

Theses and Dissertations

This thesis foregrounds the methodology of humor and play employed by Chilean artists during the late 1970s and early 1980s. I argue that, through comic relief, collaborative practice, and melodrama, artists from different fields worked together in Santiago to reimagine the relationship between intellectuals and the public sphere and criticize the Pinochet regime.

A Qualitative Exploration Of The Use Of Service Dogs In Veterans With Post Traumatic Stress Disorder And Traumatic Brain Injury, Jennifer Shiroff, Kathy Gray, Gabrielle Santulli, Stephen Didonato, Jacqueline O'Rourke Fulford

College of Nursing Faculty Papers & Presentations

Objective

This qualitative research was conducted to add to the body of knowledge that supports the benefits of service dogs (SDs), as a tertiary treatment modality, to veterans with post‐traumatic stress disorder (PTSD) and/or traumatic brain injury (TBI).

Methods

This grounded theory research design utilized open‐ended, semi‐structured interviews with veterans (n = 10) who were using SDs as a treatment modality for PTSD and/or TBI. Transcripts were analyzed using NVivo qualitative software until data saturation was achieved.

Results

Results from the data analysis identified 4 major themes with concurrent subthemes. The most prominent themes were functional status, impact of …

Stories Of Social Justice: How The Art Of Storytelling In Tristan Strong Can Heal Racial Trauma In The Unites States, Shaye Lynn Champ-Correll

English Theses, Dissertations, and Student Creative Activity

Storytelling is a vital part of the human experience. Stories can help heal trauma, help us all confront our monsters and inner demons, and can shape the way we understand ourselves and our place in the world. Kwame Mbalia’s Tristan Strong series are an example of the way stories can do all these things in themselves, and also address the ways stories do all of these things within Tristan Strong’s story. In the following thesis, I will examine the art and importance of storytelling, the ways in which stories can grow and change beyond their origins, and the ways in …

An Analytical Study On The Intervention Of The Legislature To The Constitutional Court In Indonesia Compared To Developed Countries, Mochammad Arief Agus, Andi Muhammad Irvan Alamsyah

Indonesia Law Review

Practical improvements in the national institution context brought numerous changes regarding interactions between The Constitutional Court & The legislature including contemporary polemics. The check and balances framework is important to be noticed related to the Judge’s Independence. Aswanto’s recall as one of the Judges of the Indonesian Constitutional Court encourages us to elaborate more about the essence of independence. At the same time, checks and balances should stand out. What is the legal standing of any actions taken by the parliament to the constitutional court? How do developed countries practice the relationship between the legislature and the judiciary? The answer …

Extracellular Vesicle Characteristics And Micro Rna Content In Cerebral Palsy And Typically Developed Individuals At Rest And In Response To Aerobic Exercise., Ivan Jose Vechetti Jr, Jessica Norrbom, Björn Alkner, Emma Hjalmarsson, Alexandra Palmcrantz, Eva Pontén, Jessica Pingel, Ferdinand Von Walden, Rodrigo Fernandez-Gonzalo

Department of Nutrition and Health Sciences: Faculty Publications

In this study, the properties of circulating extracellular vesicles (EVs) were examined in cerebral palsy (CP) and typically developed (TD) individuals at rest and after aerobic exercise, focusing on the size, concentration, and microRNA cargo of EVs. Nine adult individuals with CP performed a single exercise bout consisting of 45 min of Frame Running, and TD participants completed either 45 min of cycling (n = 10; TD EX) or were enrolled as controls with no exercise (n = 10; TD CON). Blood was drawn before and 30 min after exercise and analyzed for EV concentration, size, and microRNA …

Effect Of Diabetes-Associated Mutations In Kir 6.2/Sur1 On Katp Channel Activities, Yunpeng Li

McKelvey School of Engineering Graduate Student Theses & Dissertations

Maturity Onset Diabetes of the Young (MODY) is a type of diabetes, distinct from either type I or type II, that happens before age 25 (MedlinePlus, 2022). Unlike the other two more common forms of diabetes, MODY is classified as a series of monogenetic disorders (American Diabetes Association Professional Practice Committee, 2021), caused by autosomal mutations. MODY is typically characterized by insufficient secretion of insulin, a similar symptom to type I diabetes, classified into 14 different types based on mutations found on different genes. Among them, subtypes 12 and 13, also called neonatal diabetes mellitus (NDM), are caused by gain-of-function …

Spaci: Deciphering Spatial Cellular Communications Through Adaptive Graph Model, Ziyang Tang, Tonglin Zhang, Baijian Yang Ph.D., Jing Su, Qianqian Song

Publications

Cell-cell communications are vital for biological signalling and play important roles in complex diseases. Recent advances in single-cell spatial transcriptomics (SCST) technologies allow examining the spatial cell communication landscapes and hold the promise for disentangling the complex ligand-receptor (L-R) interactions across cells. However, due to frequent dropout events and noisy signals in SCST data, it is challenging and lack of effective and tailored methods to accurately infer cellular communications. Herein, to decipher the cell-to-cell communications from SCST profiles, we propose a novel adaptive graph model with attention mechanisms named spaCI. spaCI incorporates both spatial locations and gene expression profiles of …

Implementation Of The Family Help Protocol: A Feasibility Project For A West Texas Icu, Rebecca Mcclay

Dissertations

The purpose of this project was to determine if there is sufficient bedside ICU nurse buy-in to the Family HELP protocol to make implementation feasible at one county hospital in West Texas.

Living Tree Doctrines Of The Canadian Constitution And Indigenous Law, Emma C. Howes

Dalhousie Journal of Legal Studies

The living tree doctrine of the Canadian Constitution uses the metaphor of a tree to present the Constitution as a dynamic organism which can evolve over time to accommodate new influences. This essay examines the history of this doctrine along with its possible Indigenous counterparts. In this examination, both the arboreal imagery of such doctrines and their dynamic approach to law are considered. The essay explores the benefits and disadvantages of employing a living tree approach to accommodate Indigenous legal traditions within the Canadian formal legal system.

Mental Age V Chronological Age: Rethinking Our Approach To Criminal Responsibility For Developmentally Delayed Young Persons Under The Youth Criminal Justice Act, Michael Michel

Dalhousie Journal of Legal Studies

The Youth Criminal Justice Act (YCJA) is meant to ensure that only the most serious cases warrant imprisonment. Both in the pre- and post-trial stages of a criminal proceeding, the YCJA contains safeguards designed to divert youth away from correctional institutions and encourage the use of community-based services. Yet, for youth suffering from mental disorders or injuries that cause significant cognitive impairment, these safeguards can be inadequate, detrimental, or simply unavailable. To resolve this shortcoming, this article advocates using mental age, rather than chronological age, as the benchmark for determining criminal responsibility under the YCJA.

Can A Combined Agriculture And Nutrition Behaviour Change Intervention Improve Women’S Empowerment? A Mixed Methods Feasibility Study In Rural Bangladesh, Elizabeth K. Kirkwood, Michael J. Dibley, Wajiha Khatun, Gulshan Ara, Mansura Khanam, Anowarul Bokshi, Mu Li, Neeloy Ashraful Alam

The Qualitative Report

Many agricultural and home gardening interventions aim to improve the nutritional status of women and children in low- and middle-income countries by focusing on women as the recipients of the intervention and make assumptions that women will be empowered as a result. This paper examines the potential impact of an intervention study that combined home garden training and support, and nutrition behaviour change communication, with a social safety net payment, on women’s empowerment in rural Bangladesh. We assessed the implementation of this study in terms of feasibility, acceptability, and practical application. Twenty in-depth interviews were conducted with randomly selected women …

Four Students Receive Grants For Ideas Through Titan New Venture Challenge, Mj Soria

News and Events (Discontinued Series)

No abstract provided.

The Role Of Dha In The Impact Of Trem2 On Microglia Activation And Alzheimer’S Disease, Michael A. Palmieri Iii

Seton Hall University Dissertations and Theses (ETDs)

Alzheimer’s disease (AD) is a neurological disease that is associated with microglia activation. An important receptor involved in microglia activation is Triggering receptor expressed on myeloid cells 2 (TREM2). Recent studies suggest that docosahexaenoic acid (DHA) could reduce the neuroinflammation that is associated with microglia activation. We hypothesized that when DHA concentration was increased, TREM2 expression would decrease, microglia activity would be inhibited, and a resulting decrease in neuroinflammation would be observed. We examined peer-reviewed journal articles from 2017-2022 that investigated the relationship between TREM2 activation and severity of AD symptoms, the protective properties of DHA against AD, and the …

Three-Component Composite Phase-Change Material For Thermal Regulation, Bidisha Ojha

McKelvey School of Engineering Graduate Student Theses & Dissertations

Phase change materials can increase the efficiency of many energy-intensive applications, such as solar power plants, solar heating and cooling systems, heat recovery systems, photovoltaic electricity systems, and Earth satellite systems. In several proposed thermal management systems for high power electronic equipment, PCMs change phase and absorb latent heat at peak energy loads during operation, then dissipate this energy later to prevent overheating. More specifically, composite PCM’s, consisting of an organic material (e.g., paraffin) and an inorganic material (e.g., metallic alloys or salt hydrates), provide a superior balance of thermal conductivity and latent heat for thermal management. Organic PCMs have …

Ototoxicity Of Topical Antibiotic Ear Drops In Chronic Suppurative Otitis Media In Humans: A Review Of The Literature, Syed Zohaib Maroof Hussain, Syed S Hashmi, Asad Qayyum

Faculty, Staff and Student Publications

An electronic search of the literature was performed for reported cases of ototoxicity associated with the use of topical antibiotic ear drops in humans. The dosage, duration, and type of ototoxic preparations involved were recorded. Due to the scant quantity of low-quality information that is currently available, there was uncertainty about the usefulness of topical antibiotics in enhancing the resolution of ear discharge in patients with chronic suppurative otitis media. However, despite this uncertainty, there are some data to show that using topical antibiotics in comparison to a placebo or in conjunction with a systemic antibiotic may be useful. Additionally, …

Molecular Markers In Maternal Blood Exosomes Allow Early Detection Of Fetal Alcohol Spectrum Disorders, Nune Darbinian, Armine Darbinyan, John Sinard, Gabriel Tatevosian, Nana Merabova, Faith D'Amico, Tarek Khader, Ahsun Bajwa, Diana Martirosyan, Alina K Gawlinski, Richa Pursnani, Huaqing Zhao, Shohreh Amini, Mary Morrison, Laura Goetzl, Michael E Selzer

Faculty, Staff and Student Publications

Prenatal alcohol exposure can cause developmental abnormalities (fetal alcohol spectrum disorders; FASD), including small eyes, face and brain, and neurobehavioral deficits. These cannot be detected early in pregnancy with available imaging techniques. Early diagnosis could facilitate development of therapeutic interventions. Banked human fetal brains and eyes at 9−22 weeks’ gestation were paired with maternal blood samples, analyzed for morphometry, protein, and RNA expression, and apoptotic signaling. Alcohol (EtOH)-exposed (maternal self-report) fetuses were compared with unexposed controls matched for fetal age, sex, and maternal race. Fetal brain-derived exosomes (FB-E) were isolated from maternal blood and analyzed for protein, RNA, and apoptotic …

Total Transfemoral Percutaneous Endovascular Aortic Arch Repair Using 3-Vessel Inner Branch Stent-Graft, Emanuel R Tenorio, Thanila A Macedo, Laura Ocasio, Marina Dias Neto, Guilherme B Barbosa Lima, Aidin Baghbani-Oskouei, Anthony L Estrera, Abhijeet Dhoble, Shao Feng Zhou, Gustavo S Oderich

Faculty, Staff and Student Publications

Endovascular repair has been introduced to decrease the morbidity and mortality associated with open surgical repair of aortic arch pathology. We illustrate total percutaneous transfemoral approach with a 3-vessel inner branch stent-graft to treat aortic arch aneurysm. (Level of Difficulty: Advanced.).

Kras Inhibitor That Simultaneously Inhibits Nucleotide Exchange Activity And Effector Engagement, Cynthia V Pagba, Amit K Gupta, Ali K Naji, Dharini Van Der Hoeven, Kelly Churion, Xiaowen Liang, Jacob Jakubec, Magnus Hook, Yan Zuo, Marisela Martinez De Kraatz, Jeffrey A Frost, Alemayehu A Gorfe

Faculty, Staff and Student Publications

We describe a small molecule ligand ACA-14 (2-hydroxy-5-{[(2-phenylcyclopropyl) carbonyl] amino} benzoic acid) as an initial lead for the development of direct inhibitors of KRAS, a notoriously difficult anticancer drug target. We show that the compound binds to KRAS near the switch regions with affinities in the low micromolar range and exerts different effects on KRAS interactions with binding partners. Specifically, ACA-14 impedes the interaction of KRAS with its effector Raf and reduces both intrinsic and SOS-mediated nucleotide exchange rates. Likely as a result of these effects, ACA-14 inhibits signal transduction through the MAPK pathway in cells expressing mutant KRAS and …

Interventions For Promoting Physical Activity In People Newly Diagnosed With Parkinson’S Disease. A Scoping Review., J Gilby, J Marsden, B Kent, Lozano R Knight

School of Health Professions

No abstract provided.

Developing A Mcdm-Based Framework For Achieving Circular Economy Through Sustainable Ship Recycling, B Mannan, Mj Rizvi, M Dai

School of Engineering, Computing and Mathematics

As a result of the growing global population, concerns about the energy crisis and sustainability issues are studied by researchers and policymakers to make a transit from a linear to a circular economy. However, the recycling of end-of-life (EOL) ships has long been a severely marginalized research area in the field of circular economy, and many EOL ships are still adhering to the outdated linear model. The number, size, and volume of ships being built around the world have consistently increased during the past 20 years. In near future, the global ship recycling volume is anticipated to increase dramatically which …

The Microbial Etiology Of Community-Acquired Pneumonia In Adults: From Classical Bacteriology To Host Transcriptional Signatures, Naomi J Gadsby, Daniel M Musher

Faculty, Staff and Students Publications

All modern advances notwithstanding, pneumonia remains a common infection with substantial morbidity and mortality. Understanding of the etiology of pneumonia continues to evolve as new techniques enable identification of already known organisms and as new organisms emerge. We now review the etiology of pneumonia (at present often called "community-acquired pneumonia") beginning with classic bacteriologic techniques, which identified Streptococcus pneumoniae as the overwhelmingly common cause, to more modern bacteriologic studies, which emphasize Haemophilus influenzae, Staphylococcus aureus, Moraxella catarrhalis,

Pleiomorphism Plurihormonal Pit-1-Positive Macroadenoma With Central Hyperthyroidism: A Rare Case Report And Literature Review, Guiliang Peng, Chuanhong Guo, Yangfan Lv, Dandan Li, Ling Zhou, Rufei Shen, Yong Chen, Xin Zheng, Zheng Sun, Hongting Zheng, Min Long

Faculty, Staff and Students Publications

BACKGROUND: Thyrotropin-secreting pituitary neuroendocrine tumors (PitNETs) are rare pituitary adenomas that are occasionally accompanied by hypersecretion of other anterior pituitary hormones, such as growth hormone (GH) and prolactin (PRL). The clinical, biochemical, and pathological characteristics may represent diverse circumstances.

CASE PRESENTATION: In this report, a 33-year-old female diagnosed with a TSH PitNET co-secreting GH presented no obvious clinical symptoms. The main characteristics were elevated thyroid-stimulating hormone (TSH), free tri-iodothyronine (FT3), and free thyroxine (FT4) levels accompanied by slightly elevated GH and insulin-like growth factor-1 (IGF-1) levels. Magnetic resonance imaging (MRI) detected a pituitary macroadenoma (18 × 16 × 16 mm) …