Digital Commons Network^™

Trigger Related Outcomes Of Takotsubo Syndrome In A Cancer Population, Ayesha Safdar, Talha Ahmed, Victor Y Liu, Antoine Addoumieh, Ali M Agha, Dana E Giza, Dinu V Balanescu, Teodora Donisan, Tariq Dayah, Juan C Lopez-Mattei, Peter Y Kim, Saamir Hassan, Kaveh Karimzad, Nicolas Palaskas, January Y Tsai, Gloria D Iliescu, Eric H Yang, Joerg Herrmann, Konstantinos Marmagkiolis, Paolo Angelini, Cezar A Iliescu

Faculty, Staff and Student Publications

BACKGROUND: Takotsubo syndrome (TTS) occurs more frequently in cancer patients than in the general population, but the effect of specific TTS triggers on outcomes in cancer patients is not well studied.

OBJECTIVES: The study sought to determine whether triggering event (chemotherapy, immune-modulators vs. procedural or emotional stress) modifies outcomes in a cancer patient population with TTS.

METHODS: All cancer patients presenting with acute coronary syndrome (ACS) between December 2008 and December 2020 at our institution were enrolled in the catheterization laboratory registry. Demographic and clinical data of the identified patients with TTS were retrospective collected and further classified according to …

Case Report: Successful Treatment Of Late-Onset Immune Checkpoint Inhibitor-Associated Membranous Nephropathy In A Patient With Advanced Renal Cell Carcinoma, Praveen Ratanasrimetha, Vikas D Reddy, Jaya Kala, Amanda Tchakarov, William F Glass, Pavlos Msaouel, Jamie S Lin

Faculty, Staff and Student Publications

BACKGROUND: Diagnosing immune checkpoint inhibitor (ICI)-associated nephritis can be challenging since it is a rare complication of therapy, associated with a spectrum of immune-mediated pathologies, and can present months after ICI therapy discontinuation (i.e., late-onset). ICIs are increasingly administered in combination with other cancer therapies with associated nephrotoxicity, further obfuscating the diagnosis of ICI-associated nephritis. In this report, we describe the first suspected case of late-onset ICI-associated membranous nephropathy (MN) in a patient with metastatic clear cell renal cell carcinoma (RCC) who had discontinued ICI therapy 6 months prior to presentation. Prompt recognition of the suspected late-onset immune-related adverse event …

Global “Flu-Ization” Of Covid-19: A Perspective From Vietnam, Khoi Quan Nguyen, Le My Anh Nguyen, Andrew W Taylor-Robinson

Faculty, Staff and Student Publications

No abstract provided.

Formation, Antimicrobial Activity, And Biomedical Performance Of Plant-Based Nanoparticles: A Review, Ngoan Thi Thao Nguyen, Luan Minh Nguyen, Thuy Thi Thanh Nguyen, Thuong Thi Nguyen, Duyen Thi Cam Nguyen, Thuan Van Tran

Faculty, Staff and Student Publications

Because many engineered nanoparticles are toxic, there is a need for methods to fabricate safe nanoparticles such as plant-based nanoparticles. Indeed, plant extracts contain flavonoids, amino acids, proteins, polysaccharides, enzymes, polyphenols, steroids, and reducing sugars that facilitate the reduction, formation, and stabilization of nanoparticles. Moreover, synthesizing nanoparticles from plant extracts is fast, safe, and cost-effective because it does not consume much energy, and non-toxic derivatives are generated. These nanoparticles have diverse and unique properties of interest for applications in many fields. Here, we review the synthesis of metal/metal oxide nanoparticles with plant extracts. These nanoparticles display antibacterial, antifungal, anticancer, and …

Occurrence, Toxicity And Adsorptive Removal Of The Chloramphenicol Antibiotic In Water: A Review, Luan Minh Nguyen, Ngoan Thi Thao Nguyen, Thuy Thi Thanh Nguyen, Thuong Thi Nguyen, Duyen Thi Cam Nguyen, Thuan Van Tran

Faculty, Staff and Student Publications

Chloramphenicol is a broad-spectrum bacterial antibiotic used against conjunctivitis, meningitis, plague, cholera, and typhoid fever. As a consequence, chloramphenicol ends up polluting the aquatic environment, wastewater treatment plants, and hospital wastewaters, thus disrupting ecosystems and inducing microbial resistance. Here, we review the occurrence, toxicity, and removal of chloramphenicol with emphasis on adsorption techniques. We present the adsorption performance of adsorbents such as biochar, activated carbon, porous carbon, metal-organic framework, composites, zeolites, minerals, molecularly imprinted polymers, and multi-walled carbon nanotubes. The effect of dose, pH, temperature, initial concentration, and contact time is discussed. Adsorption is controlled by π-π interactions, donor-acceptor interactions, …

Comparative Analysis Of Gene Expression Patterns For Oral Epithelial Cell Functions In Periodontitis, Octavio A Gonzalez, Sreenatha Kirakodu, Linh M Nguyen, Luis Orraca, Michael J Novak, Janis Gonzalez-Martinez, Jeffrey L Ebersole

Faculty, Staff and Student Publications

The structure and function of epithelial cells are critical for the construction and maintenance of intact epithelial surfaces throughout the body. Beyond the mechanical barrier functions, epithelial cells have been identified as active participants in providing warning signals to the host immune and inflammatory cells and in communicating various detailed information on the noxious challenge to help drive specificity in the characteristics of the host response related to health or pathologic inflammation. Rhesus monkeys were used in these studies to evaluate the gingival transcriptome for naturally occurring disease samples (GeneChip® Rhesus Macaque Genome Array) or for ligature-induced disease (GeneChip® Rhesus …

Immune Response To Sars-Cov-2 Vaccine Among Heart Transplant Recipients: A Systematic Review, Saeed Shoar, Adriana C Carolina Prada-Ruiz, Gabriel Patarroyo-Aponte, Ashok Chaudhary, Mohammad Sadegh Asadi

Faculty, Staff and Student Publications

BACKGROUND: Heart transplant (HTX) recipients are at a significantly higher risk of adverse clinical outcomes, due to chronic immunosuppression and co-existence of other chronic conditions, when contracting the SARS-CoV-2 infection. Although vaccination against SARS-CoV-2 is currently the most promising measure for the prevention of severe Coronavirus Disease 2019 (COVID-19) among solid organ transplant recipients, the extent of immune response and its protective efficacy among patients receiving HTX has not been sufficiently studied.

METHODS: We performed a systematic review of the literature by inquiring PubMed/Medline to identify original studies among HTX recipients, who had received at least one dose of the …

Hispanic Ethnicity And Mortality Among Critically Ill Patients With Covid-19, Ana C Ricardo, Jinsong Chen, Stephanie M Toth-Manikowski, Natalie Meza, Min Joo, Shruti Gupta, Deepa G Lazarous, David E Leaf, James P Lash

Faculty, Staff and Student Publications

BACKGROUND: Hispanic persons living in the United States (U.S.) are at higher risk of infection and death from coronavirus disease 2019 (COVID-19) compared with non-Hispanic persons. Whether this disparity exists among critically ill patients with COVID-19 is unknown.

OBJECTIVE: To evaluate ethnic disparities in mortality among critically ill adults with COVID-19 enrolled in the Study of the Treatment and Outcomes in Critically Ill Patients with COVID-19 (STOP-COVID).

METHODS: Multicenter cohort study of adults with laboratory-confirmed COVID-19 admitted to intensive care units (ICU) at 67 U.S. hospitals from March 4 to May 9, 2020. Multilevel logistic regression was used to evaluate …

Safety Of Exercise For Adults With Thoracic Aortic Aneurysms And Dissections, Jesse Li, Alexandra Boyd, Michael Huang, Joshua Berookhim, Siddharth K Prakash

Faculty, Staff and Student Publications

BACKGROUND: Current guidelines for patients with thoracic aortic aneurysms or dissections (TAD) restrict vigorous exertion with the intention to prevent acute aortic dissections. However, a safe threshold for exercise intensity has not been established for TAD patients. In this study, we measured exertional changes in systolic and diastolic blood pressure during isometric and dynamic exercises in a cohort of TAD patients to determine safety of moderate intensity exercise.

METHODS: Thirty-one adults with TAD and 14 controls were recruited from UTHealth outpatient clinics. All participants completed an exercise protocol consisting of two circuits of five moderate intensity exercises: hand grips, leg …

Chapter 10. Evolving Models Of Mission: Dayton, Ohio, Francis Tandoh C.S.Sp.

Spiritan Horizons

No abstract provided.

A Proposed Grief Support Group Intervention For College Students At A University Counseling Center, Kyle Cacoyannis

Graduate School of Professional Psychology: Doctoral Papers and Masters Projects

The current paper draws upon previous literature, along with the author's experience facilitating grief support groups to introduce a proposed grief support group intervention that could be implemented with college students at university counseling centers in the United States and potentially abroad. The author discusses literature on grief, grief support groups at university counseling centers and in other settings, and presenting problems related to grief among college students and young adults which help inform the design of the proposed intervention. The group intervention design is outlined in detail in the Appendix section, however the Method section gives a brief synopsis …

Theater And Peacebuilding In Post-Conflict Settings: Participants’ Experiences In The Morning Star Theater Program In South Sudan, Shiphrah Mutungi Akandiinda

Antioch University Dissertations & Theses

This dissertation explores the role of theater for peacebuilding in post-conflict settings through the analysis of experiences of participants in the Morning Star Forum Theater for Peacebuilding in South Sudan. Arts-based activities, including theater, have increasingly gained momentum as viable interventions for peacebuilding in post-conflict zones. Much of the existent research fails to capture the experiences of the theater participants themselves. Using narrative inquiry, this study interviewed 12 community members who participated in the Morning Star Forum Theater event. In particular, this study focused on how experiences of Morning Star Theater events impacted interpersonal growth and relationship-building, thus positively impacting …

Afroam: A Virtual Film Production Group, Bill Taylor Jr.

Antioch University Dissertations & Theses

Because of the gatekeeping practices of the Hollywood film industry, and the high cost of both filmmaking and distribution in general, Afro-American filmmakers have struggled to produce films with “global reach.” This study visits the possibility of Afro-American filmmakers using alternative technologies and infrastructures to produce high-quality films, thereby bypassing the high cost and exclusionary practices of Hollywood studios. Using new 21st-century digital technology, this study involved the creation of a small geographically dispersed virtual film production team. The study’s foundational framework was a constructivist qualitative research paradigm, using Action Research, and supported by 24 months of triangulated data from …

Exploring The Leadership-As-Practice Of Middle Managers Engaged In Organizational Changes In An Asia Pacific Multinational Setting, Eric Kung

Antioch University Dissertations & Theses

There has been a great need for leadership studies on middle management, particularly in the Asia Pacific context. This study explored the leadership practices of middle managers engaged in leading organizational changes of multinational corporations (MNCs), within the Asia Pacific context. Organization ethnography was used as the research method. The ethnographer observed and analyzed the actual practice of middle managers of a multinational manufacturing company located in China for six months. The findings showed that middle managers played significant roles in communication and execution in leading organizational changes. The study also showed that change management could be a dynamic process …

Reframing Leadership Narratives Through The African American Lens, Marion Missy Mcgee

Antioch University Dissertations & Theses

Reframing Leadership Narratives through the African American Lens explores the context-rich experiences of Black Museum executives to challenge dominant cultural perspectives of what constitutes a leader. Using critical narrative discourse analysis, this research foregrounds under-told narratives and reveals the leadership practices used to proliferate Black Museums to contrast the lack of racially diverse perspectives in the pedagogy of leadership studies. This was accomplished by investigating the origin stories of African American executives using organizational leadership and social movement theories as analytical lenses for making sense of leaders’ tactics and strategies. Commentary from Black Museum leaders were interspersed with sentiments of …

Traditional Healing In Psychology On The Caribbean Island Of Montserrat, West Indies, Yvette Adelcia Cabey

Antioch University Dissertations & Theses

In Montserrat, traditional healing medicines consist of herbal treatments and customary therapeutic methods such as ritual practices and herbal teas also known as “Bush and Weed” (Duberry, 1973, p.1). The purpose of this study is to discuss herbs known as “Bush,” in Montserrat, and how they benefit psychological wellbeing among the communities in Montserrat. A subsequent intention of this study is to address how an understanding of Montserratian Traditional Healing remedies can be beneficial to Western Psychological practice and enhance the efficacy for psychological healing. The gap in the literature indicates that few studies are examining mental health methods in …

Therapist Self-Reported Attachment Organization And Countertransference Responses To Psychotherapy Clients, Morgan Janay Pell

Antioch University Dissertations & Theses

Therapists experience thoughts, feelings, and behaviors in response to their clients, which are sometimes referred to as countertransference. Such responses may be influenced by the therapist’s personal history, including the quality of their attachment experiences. Research has demonstrated that adult attachment organizations influence a person’s cognitive, behavioral, and affective responses toward close others, thus providing a useful framework for understanding some countertransference experiences of therapists. This quantitative study sought to add to the existing literature by examining the relationship between therapist self-reported attachment organization and countertransference responses to clients. Seventy-three therapists participated in this study, including licensed psychologists, doctorate-level psychologists, …

Narrative Enhancement And Cognitive Therapy With Correctional Psychiatric Patients: A Pilot Study, Richelene Cesar

Antioch University Dissertations & Theses

Narrative Enhancement and Cognitive Therapy (NECT) is a manualized, group-based intervention that was originally developed to treat self-stigma among individuals who present with severe and persistent mental illnesses (SPMIs; Roe, Lysaker, & Yanos, 2013). NECT has been shown to effectively reduce these individuals’ experience of self-stigma, and diminish its negative effects on their hope, self-esteem, self-efficacy, and quality of life (Yanos, Roe, & Lysaker, 2011). Supportive literature is scarce regarding NECT’s efficacy with people who have multiple stigmatized identities. For the purposes of this pilot study, NECT was implemented with a correctional psychiatric population. Research supports this population is doubly, …

Women Seeking The Public School Superintendency: Navigating The Gendered And Racialized-Gendered Job Search, Rachel M. Roberts

Antioch University Dissertations & Theses

I have been an educator for my entire career. First, as a teacher and over the last decade as a school administrator. During my tenure, I have continually noticed the underrepresentation of women in the highest office: the school superintendent. This has vexed me over the years, and as a scholar practitioner in leadership and change, I have devoted my research to unearthing the inequalities and disproportional realities that exist within high-profile leadership, particularly the public school superintendency. Utilizing a grounded theory approach, this dissertation sought to better understand what happens at the micro-level, especially during and after the superintendent …

Content Analysis On Hispanic Populations Across Marriage And Family Therapy Journals, Maya S. Iturra

Antioch University Dissertations & Theses

There is ambiguity on what kind of coverage of Hispanic populations in counseling journals is often used by couple/marriage and family therapists (C/MFTs) and researchers. The aims of this study are to identify how these journals consider Hispanic populations and what advice is provided when working with Hispanic populations. An explanatory sequential mixed method content analysis study was conducted. The first quantitative stage used descriptive statistics to analyze 17 journals’ articles between 2011-2020 regarding the type of research designs used, the frequency of articles that fit the inclusion criteria for the study, and the use of psychosocial terms (i.e., acculturation, …

The Relationships Between Dimensions Of Inclusive Leadership And Aspects Of Employee Engagement: Crucial Connections For Organizational Success, Rosalind F. Cohen

Antioch University Dissertations & Theses

In light of the current economic conditions in the United States brought about by the COVID pandemic, the war for talent is at a high point, and the acquisition and retention of qualified employees are highly competitive. Because employees want to feel challenged by their work and need to feel a sense of belonging, organizations that create engaging and inclusive cultures are at an advantage and need to understand how leadership behaviors can impact these cultures. This three-phased exploratory concurrent mixed-methods research study posed two questions to bring light to the relationship between Inclusive Leadership, Employee Engagement, and individual or …

Toward Socially Equitable Conditions: Change In Complex Regulatory Systems, Katherine A. Hoffman

Antioch University Dissertations & Theses

The purpose of this qualitative participatory action research was to explore how complexity is engaged and experienced in complex regulatory systems, and to understand how cannabis might be regulated in ways that lead to socially equitable conditions. This was accomplished by studying the lived experiences of governmental leaders charged with the responsibility of establishing regulatory frameworks for legalized cannabis where none previously existed. Using the learning history methodology, the study deeply explores the ways that complex systems coexist by capturing the lived experiences of research participants and enhance theoretical understanding of complex regulatory systems. Data collection occurred through reflective interviews, …

Imposter Phenomenon And Ces Doctoral Students, Michael Drane

Antioch University Dissertations & Theses

The aim of the study was to explore the lived experience of counselor education and supervision students who reported experiencing symptoms of imposter phenomenon (IP). The population included counselor education and supervision students in their first year of their program, with a sample of convenience (N = 4). The method used in this study was an interoperative phenomenological analysis. Data analysis revealed four major themes: (a) counselor education students express self-doubt, lack of confidence and concern about competence, (b) students rate different levels of competence in counselor education and supervision roles, (c) instructor feedback impacts student perceptions of competence, and …

Adverse Religious Experiences And Lgbtq+ Adults, Alex Fox

Antioch University Dissertations & Theses

The aim of this study is to explore the ways in which LGBTQ+ people are affected by adverse or traumatic experiences related to religion or spirituality. Many LGBTQ+ adults were reared in environments where negative, disaffirming beliefs or teachings about sexual orientation or gender identity were pervasive. This study utilized a mixed-methods approach to data collection and analysis. Participants responded to a brief online survey, the data from which was used for quantitative statistical analysis. Twelve participants were selected at random from a pool of survey volunteers and took part in in-depth interviews regarding adverse religious experiences (AREs). Results of …

The Mechanism Of Reducing Anxiety Through Mindfulness Interventions: Digital Therapeutic Program, Maria Neizvestnaya

Antioch University Dissertations & Theses

The COVID-19 pandemic exacerbated the prevalence of anxiety disorders, making it a population health concern in the United States and worldwide. The growing need for effective prevention and treatment of anxiety coincides with a deficit of mental health providers and physicians. With the healthcare system currently overwhelmed and the slow training pipeline of new providers, the gap between patient demand and treatment providers will not be closed in the next decade. There is a growing need for evidence-based treatments for anxiety disorders that can increase access to care while addressing the underlying mechanisms of anxiety. Digital therapeutics is a fast-developing …

Social And Cultural Considerations In Accessing Mental Health Treatment In The Gambia, West Africa, Safiya Njai

Antioch University Dissertations & Theses

This study examines the social and cultural considerations in accessing mental health treatment in The Gambia, West Africa. Participants were recruited from The Gambia for a qualitative study that included semistructured interviews (N = 17). A team of analysts identified five themes. The results highlighted social and cultural conceptualizations of mental health and mental illness, sociocultural determinants of health, interventions, barriers to care, and the legal framework to support mental health change. These findings are important for counselors to understand different perceptions of mental health and mental illness and the associated stigma. Furthermore, several opportunities for advocacy in The Gambia …

Sdrc Annual Report 2021-2022, Connie Jan Maraan

SDRC Publications

Despite the pandemic, our Center was still able to continue its operations. A manifestation of its agility and ingenuity, SDRC has managed a great number of projects and activities outnumbering the pre-pandemicyears. The Center has conducted capacity- building seminars, both paid and pro-bono,with our partners.

The Impact Of Perceived Manipulation, Motives, And Ethicality In Cause-Related Marketing: A Crm+ Model, Nathan W. Twyman, Sarah M. Stanley, Cassandra C. Elrod, Tamara M. Masters

Business and Information Technology Faculty Research & Creative Works

We Developed a CRM+ Model using Experimentation and Structural Equation Modeling Analysis. CRM+ Demonstrates Previously Unexplored Interrelationships among Consumer-Perceived Manipulation, Brand Motives, Perceived Ethicality of the Cause-Related Marketing, and Brand Attitude. CRM+ Reveals that Perceived Ethicality of the CRM Has a Significant Positive Effect on Brand Attitude, Though It is Not as Pronounced as the Effect of Perceived Altruistic Motives. Egoistic Motives Decrease Ethicality Perceptions But Has No Direct Effect on Brand Attitude. Altruistic Motive Perceptions Diminish Egoistic Motive Perceptions. CRM+ Suggests Marketing Managers Should Prioritize Emphasizing Altruistic Motives and Ethicality of the Partnership over Downplaying Egoistic Motives.

Managing Business Relationships For Social Impact: Introduction To The Special Issue, Maciej Mitręga, Dariusz Siemieniako, Krzysztof Kubacki, Stefanos Mouzas

Plymouth Business School

No abstract provided.

The Role Of Green Infrastructure In Pluvial Flood Management And The Legislation Surrounding It: A Case Study In Bristol, Uk, Dudley Saunders, John Martin

Professional Services

Surface water flooding is an issue which has required an increased level of addressment over the past two decades, with the methods used to combat flood events seeing an evolution. This evolution has been influenced heavily by multi-scale legislations and policies, which has pushed for more holistic methods for pluvial flood management. This review will analyse how Bristol City Council have implemented these multi-scale pieces and what has been put in place to encourage sustainable flood management. This will be done through a purposive review of the literature and an extensive review of legislation and policies on a national, European, …