Digital Commons Network^™

An In Vitro 3d Model To Investigate Iol: Posterior Lens Capsule Interactions On Lens Epithelial Cell Responses, Joyita Roy

Bioengineering Dissertations - Archive

ABSTRACT: Posterior Capsule Opacification (PCO) is the most common complication associated with Intraocular Lens (IOL) implantation. The disease is caused by the infiltration and proliferation of Lens Epithelial Cells (LEC) into the interface between the IOL and Posterior Lens Capsule (PLC). The severity of these cell responses depends on a lot of factors like the IOL design, IOL material, and interaction between the IOL and the posterior lens capsule. While some studies have also shown that adsorption of certain proteins present in the PLC, like fibronectin, may affect IOL-induced PCO in the clinical setting, the mechanism governing such interactions is …

Spare The Rod: African American Students’ Experience Of Postsecondary Student Conduct Processes, Melissa Sanders

Educational Leadership & Policy Studies Dissertations - Archive

Although African Americans enroll at postsecondary institutions at similar rates as other ethnic groups, consistently, they lag in degree completion. This has led to lower wages, fewer employment opportunities, and higher health disparities among African Americans. Consequently, the literature is full of studies attempting to increase Black student degree attainment. This includes their perception of campus climates, academic preparedness, and sense of belonging. However, other opportunities to promote and encourage African American scholastic success, such as the disciplinary process, are understudied. To address this gap, I utilized a phenomenological qualitative study to examine the way African Americans perceived the impact …

Targeted Drug-Loaded Nanoparticle System (Tdnps) To Ameliorate And Treat Idiopathic Lung Fibrosis, Harish Ramachandramoorthy

Bioengineering Dissertations - Archive

Idiopathic pulmonary fibrosis (IPF) is a fatal progressive disease with a dismal prognosis and 3-5 years of survival. Up to date, there are no effective treatments, and a few current therapies that do not ameliorate the pulmonary fibrosis but rather just increase the survival time by 2-3 years. The major factor limiting the treatment is the lack of targeted therapies to deliver the drugs past the mucosa, into the disease microenvironment. To combat this disease, we proposed a localized therapy via our targeted drug-loaded nanoparticles (TDNPs) to effectively deliver drugs and treat lung fibrosis. Our objective was to design TDNPs …

Performance Evaluation Of The Modified Moisture Barrier In Stabilizing Shallow Slope Failures, Muhasina Manjur Dola

Civil Engineering Dissertations - Archive

Each year significant number of highway slope failures are reported in the United States, especially in states like Texas where expansive clayey soil is prevalent. Slopes constructed over expansive clay often experience recurring shallow failures following their construction which poses maintenance problems to the Texas Department of Transportation (TxDOT). These shallow slope failures can be primarily attributed to the considerable volume change that expansive clay soil undergoes from seasonal climatic variation. Furthermore, under unsaturated conditions during dry periods, high matric suction (i.e., negative porewater pressure) exists in soil slopes. The existence of matric suction contributes to the shear strength of …

The Me You Can’T See: Stories Of Black Male Elementary Teachers’ Experiences And Decisions To Teach, An Endarkened Storywork Study, Trevor Dustin Mccray

Educational Leadership & Policy Studies Dissertations - Archive

Black male teachers in PK-12 make up less than 2% of the teacher workforce with an undetermined representation in elementary education. Although there have been efforts to increase their representation in the field, there remains a lack of Black males entering the classroom as teachers. In addition, there has been limited research examining ecological systems' influence on Black male teachers' elementary teacher experiences and their decisions to teach in early childhood education. In response, this proposed qualitative Endarkened Storywork study examined Black male elementary teachers' experiences and highlighted the perceived influence of Black males teaching in early childhood education through …

Development Of A Decesion Tree To Rehabilitate Or Replace The St. Francis Bridge Over Ih-30, Md Farhan Abir

Civil Engineering Theses - Archive

ABSTRACT: The ASCE infrastructure report card indicated that about 42% of the nation’s bridges are over 50 years old, and 7.5% of the bridges are structurally deficient. The 61-year-old St. Francis bridge over IH-30 is one of the Texas Department of Transportation (TxDOT) bridges that exhibit significant deterioration in the superstructure, including potholes and delamination in the deck. The bridge was load posted to 28,000 lb. limit and has substandard vertical and horizontal clearances to the bottom chord of the beams and supporting piers, respectively, which creates a high risk for vehicle impact. In 2017, an over-height truck struck the …

Study Of The Impact Of Atmospheric Variability On Subsurface Methane Emissions: Application To Leak Detection And Quantification For Underground Natural Gas Pipeline Leaks, Shanru Tian

Civil Engineering Dissertations - Archive

Natural gas (NG), taken as a bridging fuel for achieving a low-carbon future, has rapidly grown to be a significant component of the global energy system and requires extensive pipeline infrastructures, most of them buried underground. Fugitive methane (CH4) emissions from NG pipeline leaks pose environmental, safety, and economic threats to the public. An effective leak detection and quantification (LDAQ) survey method is critical to identifying a leak and assessing the size when it has occurred, thus initiating appropriate response actions to repair it and accounting for the environmental risks accurately. However, gaps exist between LDAQ survey methods, and the …

Investigation Of Models To Predict The Remaining Useful Life Of Prestressed Concrete Cylinder Pipe, Ahmad Mahmoud Jibreen

Civil Engineering Dissertations - Archive

The water distribution system in the United States consists of 2.2 million miles of pipelines with water main breaks that the American Society of Civil Engineers (ASCE) 2021 Report Card estimated results in six billion gallons of drinking water lost daily. Detecting the state of pipeline deterioration should always be a top priority in the water pipeline industry This dissertation statistically evaluates data from more than 70,000 electromagnetic inspections that have been performed since the installation of these pipes in 1971. The scope of this dissertation is related to performance and degradation of prestressed concrete cylinder pipe (PCCP) which is …

Factors Affecting Health-Seeking Behaviour Among Men Who Have Sex With Men In Starehe Sub-County, Nairobi City County, Anthony Omariba

MSc in Advanced Practice Nursing

Men who have sex with other men (MSM) exist in Africa, as they do elsewhere. The continued proscription of MSM behavior leads to exclusion and discrimination. According to a global report, MSMs are responsible for most HIV transmission. MSMs in Kenya constantly fear being hurt because of their sexual orientation, and there is scant knowledge of their health-seeking behavior. There is a need to improve the health of this group to lower disease spread to achieve global HIV reduction. This study aims to explore MSM healthcare-seeking behavior, describe barriers to healthcare-seeking, and establish perceptions of the sexual risks associated with …

Brain Waste Among Highly Skilled Immigrants In The United States, Kimberly Alva-Chavers Gardner

Master's Projects and Capstones

The issue of brain waste and underemployment among highly skilled immigrants is a key issue facing the United States today. This problem of equity has turned into an issue of economic stability in a country with a waning population whose workforce will soon depend on immigrant and international workers. Multiple agencies, including government programs and nonprofits, are attempting to address this issue from a language learning perspective. Using the theoretical framework of Cultural Capital and Community Cultural Wealth, this research project suggests that the key to reducing brain waste and underemployment among highly skilled immigrants is to take the focus …

Democracy And Schooling: The Paradox Of Co‐Operative Schools In A Neoliberal Age?, Tom Woodin, Cath Gristy

Plymouth Institute of Education

From the first co-operative trust school at Reddish Vale in Manchester in 2006, the following decade would witness a remarkable growth of ‘co-operative schools’ in England, which at one point numbered over 850. This paper outlines the key development of democratic education by the co-operative schools network. It explains the approach to democracy and explores the way values were put into practice. At the heart of co-operativism lay a tension between engaging with technical everyday reforms and utopian transformative visions of an educational future. A new arena of debate and practice was established with considerable importance for our understanding of …

Optimal Channel Strategy Of Luxury Brands In The Presence Of Online Marketplace And Copycats, Sarah Yini Gao, Wei Shi Lim, Ziqiu Ye

Research Collection Lee Kong Chian School Of Business

The strategic interaction between authentic luxury brands and their copycats has evolved since the proliferation of online marketplaces. Using a game-theoretic framework, we examine how an authentic luxury brand, observing the strategic behavior of its competing copycats, should make its optimal entry decision to a third-party online marketplace. Our findings reveal that the authentic luxury brand does not sell on the online marketplace when either the quality or the physical resemblance of the copycat to the authentic luxury brand is high. This contributes to the related literature by offering an explanation for the increasing quality of copycats amid the e-commerce …

Charting New Courses To Enter Foreign Markets: Conceptualization, Theoretical Framework, And Research Directions On Non-Traditional Entry Modes, Keith D. Brouthers, Liang Chen, Sali Li, Noman Shaheer

Research Collection Lee Kong Chian School Of Business

Recent advances in digitalization and increasing integration of international markets are paving the way for a new generation of firms to use non-traditional entry modes that are largely marginalized in previous entry mode studies. While extant research revolves around the level of resource commitment and control in foreign activities, non-traditional modes are encapsulated by the extent of embeddedness required for exploring new and/or exploiting existing resources. In particular, we draw attention to four such categories of non-traditional entry modes the literature has touched on, i.e., capital access, innovation outposts, virtual presence, and the managed ecosystem. We explore the key attributes, …

December 1, 2022, James Madison University

The Breeze, 2020-

The Breeze is the student newspaper of James Madison University in Harrisonburg, Virginia.

The Impact Of Subscription Programs On Customer Purchases, Raghu Iyengar, Young-Hoon Park, Qi Yu

Research Collection Lee Kong Chian School Of Business

Subscription programs have become increasingly popular among a wide variety of retailers and marketplace platforms. Subscription programs give members access to a set of exclusive benefits for a fixed fee upfront. In this paper, we examine the causal effect of a subscription program on customer behavior. To account for self-selection and identify the individual-level treatment effects, we combine a difference-in-differences approach with a generalized random forests procedure that matches each member of the subscription program with comparable non-members. We find subscription leads to a large increase in customer purchases. The effect of subscription is economically significant, persistent over time, and …

The Value Of Fiduciary Duties: Evidence From En Bloc Sales In Singapore, Jianfeng Hu, Kelvin F. K. Low, Wei Zhang

Research Collection Lee Kong Chian School Of Business

This paper examines the impact of fiduciary duties on collective asset sales in the case of owners acting as delegates for other owners, thereby potentially inducing conflicts of interests. Our identification strategy exploits a unique legal shock in Singapore, which established fiduciary duties in those transactions in the real estate market known colloquially as en bloc sales. The imposition of fiduciary duties caused the price premium of units sold via en bloc sales to increase over units ineligible for en bloc sale, as well as over units that, although eligible for en bloc sale, are sold individually. In addition, this …

Learning From Manipulable Signals, Mehmet Ekmekci, Leandrro Gorno, Lucas Maestri, Jian Sun, Dong Wei

Research Collection Lee Kong Chian School Of Business

We study a dynamic stopping game between a principal and an agent. The agent is privately informed about his type. The principal learns about the agent’s type from a noisy performance measure, which can be manipulated by the agent via a costly and hidden action. We fully characterize the unique Markov equilibrium of this game. We find that terminations/ market crashes are often preceded by a spike in (expected) performance. Our model also predicts that, due to endogenous signal manipulation, too much transparency can inhibit learning. As the players get arbitrarily patient, the principal elicits no useful information from the …

Nature Tech: A Nascent Ecosystem, Simon J.D. Schillebeeckx

Research Collection Lee Kong Chian School Of Business

When people talk about climate tech, they tend to mean carbon tech. It’s all carbon tunnel vision: Carbon footprint, carbon equivalent, carbon credit, carbon compensation, carbon emission reductions, carbon offsets, decarbonization and so on. By extension, the entire debate about energy transition, energy transformation, clean power and green energy is similarly a debate that is largely held within the carbon tunnel. Make no mistake about it. These are important topics to address. The energy transition will not only prevent catastrophic climate change but have massive benefits for human health by tackling fossil-fuel induced air pollution at the source.As the above …

Biomechanical And Sensory Feedback Regularize The Behavior Of Different Locomotor Central Pattern Generators, Kaiyu Deng, Hillel J. Chiel, Roger D. Quinn

Faculty Scholarship

This work presents an in-depth numerical investigation into a hypothesized two-layer central pattern generator (CPG) that controls mammalian walking and how different parameter choices might affect the stepping of a simulated neuromechanical model. Particular attention is paid to the functional role of features that have not received a great deal of attention in previous work: the weak cross-excitatory connectivity within the rhythm generator and the synapse strength between the two layers. Sensitivity evaluations of deafferented CPG models and the combined neuromechanical model are performed. Locomotion frequency is increased in two different ways for both models to investigate whether the model’s …

Forest Structure And Composition Alleviate Human Thermal Stress, Loïc Gillerot, Dries Landuyt, Rachel Oh, Winston T. L. Chow, Et Al

Research Collection College of Integrative Studies

Current climate change aggravates human health hazards posed by heat stress. Forests can locally mitigate this by acting as strong thermal buffers, yet potential mediation by forest ecological characteristics remains underexplored. We report over 14 months of hourly microclimate data from 131 forest plots across four European countries and compare these to open-field controls using physiologically equivalent temperature (PET) to reflect human thermal perception. Forests slightly tempered cold extremes, but the strongest buffering occurred under very hot conditions (PET >35°C), where forests reduced strong to extreme heat stress day occurrence by 84.1%. Mature forests cooled the microclimate by 12.1 to …

Heat And Colonial Weather Science In The Straits Settlements C. 1820-1900, Fiona Williamson

Research Collection College of Integrative Studies

Historical explorations of tropical heat in a colonial context have largely focussed on two interconnected spheres: colonial perceptions of place and body or, the implications of heat on different bodies in medical thought and practice. This paper seeks to move the discussion towards a history of colonial scientific thought about heat as component of weather and of escalating nature-induced hazards, studied in the observatory or meteorological department. A central theme is to think about heat in its relationship to nascent meso-scale atmospheric knowledge, meteorological theory and, as a by-product of urbanisation and land-use change. In so doing, it conceptualises the …

Vista: December 1, 2022, University Of San Diego

USD Vista (1965-)

No abstract provided.

The Central Valley Transportation Challenge, Christian Wandeler, Steve Hart

Mineta Transportation Institute

The Central Valley Transportation Challenge provides underserved minority students, who are primarily from rural areas, with high quality transportation-related educational experiences so that they learn about transportation-related topics and opportunities in transportation careers. The CVTC is a project-based learning program that brings university faculty and students to K–12 classrooms in rural areas. The project operated with three main objectives: (1) support K–12 teachers’ understanding and implementation of the CVTC programs; (2) connect K–12 students with university faculty and students, and transportation professionals through the CVTC program; and (3) develop an online hub with transportation-related lesson plans and sequences. The results …

Pharmacogenomics Translation In A Community Medical Context Using A Diffusion Of Innovations Framework: Provider Perspectives And Evaluation Implications, Sabrina Ewald Holley

Dissertations

Translation, in the context of medical research, is a process that describes how knowledge and innovation move and change into real world applications and outcomes. This study explores the translation of a medical innovation, pharmacogenomics (PGx), from research into clinical practice using the perspectives of medical providers in a community setting. PGx is the influence of a person’s genetics on drug response. Despite being available for over a decade, PGx testing is not widely adopted. Prior research primarily examined PGx translation in large academic medical centers, but not much is known about it in community practice settings. A better understanding …

Universal Pre-K In Comstock Public Schools, Meadow A. Nuyen

Dissertations

In 1971, President Nixon vetoed legislation that would have created federal funding for the education of kids under age five. With the veto, President Nixon reaffirmed that, except for poor children, the education and care of the children is the responsibility of the family, not the government. Yet over 31 years later, 41 states and the District of Columbia provide state-funded preschool (Waxman, 2021). Preschool in the state of Michigan is not automatically provided as K-12 education is. This study examined the beliefs of staff in Comstock Public Schools regarding Universal Pre-K, tuition-free preschool for all 4-year-olds. Participants included district …

Don’T Judge A Book By Its Covr: Learning And Training In Virtual Reality; The Effects Of Two Levels Of Immersion, Kendall Carmody, Meredith Carroll

Aeronautics Faculty Publications

Immersive devices, such as virtual reality (VR) devices are swiftly being integrated into military and civil operations as advanced tools for training, with studies observing the beneficial aspects of employing these devices for training cognitive skills (Xie et al., 2021). However, further research is needed to understand specific characteristics of the learning effectiveness of the technology and identify which levels of immersion benefit specific learning constructs in training. This study examined the effect of immersion on four constructs related to learning, including memory retention, learner engagement, learning performance in the form of knowledge acquisition, and perceived learning in a virtual …

Student And Teacher Perspectives On Asynchronous Learning During The Covid Pandemic, Michele Ehrhart

Education Doctorate Dissertations

The COVID Pandemic shut down schools across the country, leaving K-12 schools unprepared for virtual learning. In this mixed methods study, I examined data gathered from my 8th-grade science classes to assess the effectiveness of asynchronous instruction. My original research question was: How much if at all, did learning outcomes differ as a function of how the lessons were taught (uninterrupted instructional video versus interrupted/interactive Edpuzzle video)? Based on a preliminary examination of data, my study expanded into how self-regulated learning affected students’ comprehension, interest, and motivation. Study results showed no statistical differences in students’ comprehension based on how lessons …

Bridgewater Review, Vol. 40, No. 2, December 2022

Bridgewater Review

No abstract provided.

Uis Bulletin, Volume 64, No. 2, December 2022, Nivaldo Colzato

UIS Bulletin

This edition from December 2022 includes information from the UN-Water Summit on Groundwater 2022 at the UNESCO Headquarters in Paris.

Contents: Editorial: The motto that builds the UIS -- President’s Column: “History, Present and Vision” -- UIS President’s Report to the General Secretary -- The Report of the UIS General Secretary -- UIS Treasurer’s Report to the General Assembly -- The closing of the International Year of Caves and Karst 2021/22 -- The first years of the UIS -- The new UIS Bureau 2022-2025 -- The UIS Archive in Postojna, Slovenia -- Report of Commission on Artificial Cavities -- Report …

Garcia Family History, Austin Garcia

Your Family in History: HIST 550/700

The Family History of

Austin D. Garcia

2 September 2022

Austin Garcia authored this family history as part of the course requirements for HIST 550/700 Your Family in History offered online in Fall 2022 and was submitted to the Pittsburg State University Digital Commons. Please contact the author directly with any questions or comments: [email protected]