Digital Commons Network^™

Sources Of Calcium At Connexin 36 Gap Junctions In The Retina, Pui Man Rosalind Lai, Jee-Yeon Ryu, Sang-Cheol Park, Bradley A Gross, Lawrence D Dickinson, Sarajune Dagen, Mohammad Ali Aziz-Sultan, Alan S Boulos, Daniel L Barrow, H Hunt Batjer, Spiros Blackburn, Edward F Chang, P Roc Chen, Geoffrey P Colby, Garth Rees Cosgrove, Carlos A David, Arthur L Day, Kai U Frerichs, Mika Niemela, Steven G Ojemann, Nirav J Patel, Xiangen Shi, Edison P Valle-Giler, Anthony C Wang, Babu G Welch, Edie E Zusman, Scott T Weiss, Rose Du

Faculty, Staff and Student Publications

Background and Objectives

While somatic mutations have been well-studied in cancer, their roles in other complex traits are much less understood. Our goal is to identify somatic variants that may contribute to the formation of saccular cerebral aneurysms.

Methods

We performed whole-exome sequencing on aneurysm tissues and paired peripheral blood. RNA sequencing and the CRISPR/Cas9 system were then used to perform functional validation of our results.

Results

Somatic variants involved in supervillin (SVIL) or its regulation were found in 17% of aneurysm tissues. In the presence of a mutation in the SVIL gene, the expression level of SVIL …

A Survey Based-Study Reviewing The Career Opportunities For Student In Radiological Technology, Tatiana Ryzhakova, Mikhail Kun, Peber Dejesus, Zoya Vinokur

Publications and Research

Recent graduates lack the knowledge of many career opportunities there is after earning a Radiology Technology (RT) certification. The purpose of this study is to investigate how much knowledge students have as a student becomes certified for RT. This study will also represent RT workers' experience today. Questionnaires will be spread to the students in order to determine the level of knowledge of career opportunities they have in the career. The in-depth questions will target the career options in the radiology field; they also will include questions that ask for the age and demographics of students forming the part of …

Spf-R Online User Guide, Eric Green, Paul Ross, Christopher Blackden, William Staats, Reginald Souleyrette

Kentucky Transportation Center Research Report

SPF-R Online greatly improves and simplifies the SPF development process. Building on the original SPF-R script, the online tool eliminates many of the technical barriers associated with the original process, allowing for a much larger audience to take advantage of SPF-R’s capabilities. Like the original SPF-R script, SPF-R Online lets users quickly explore the effect of roadway network heterogeneity on SPF development, compare CURE plots , and compare goodness-of-fit measures to decide which SPF is most appropriate for a given dataset.

Increased Bundle-Sheath Leakiness Of Co2 During Photosynthetic Induction Shows A Lack Of Coordination Between The C4 And C3 Cycles, Yu Wang, Samantha S. Stutz, Carl J. Bernacchi, Ryan A. Boyd, Donald R. Ort, Stephen P. Long

United States Department of Agriculture-Agricultural Research Service / University of Nebraska-Lincoln: Faculty Publications

Use of a complete dynamic model of NADP-malic enzyme C4 photosynthesis indicated that, during transitions from dark or shade to high light, induction of the C4 pathway was more rapid than that of C3, resulting in a predicted transient increase in bundle-sheath CO2 leakiness (ϕ). Previously, ϕ has been measured at steady state; here we developed a new method, coupling a tunable diode laser absorption spectroscope with a gas-exchange system to track ϕ in sorghum and maize through the nonsteady-state condition of photosynthetic induction. In both species, ϕ showed a transient increase to > 0.35 before declining to a steady state …

Nation-Building And Africa's Development: A Historical And Philosophical Analysis, Adewale Onagbesan

Young African Leaders Journal of Development

From the 1960s onwards until recent time, a number of African States across the various regions have been faced with differing challenges that confront either stability, sovereignty, and in some cases, their permanent existence as evident during the period 1960-70 which was widely referred to as the decade of optimism, and the period 1970-80 which was clearly referred to as the decade of pessimism due to the number of events that manifested. Clearly in the light of this, Nation-Building in Africa has experienced chequered fortune in the past half a century of independence, up to present times, and the challenge …

Spac Attack, Justin Kuehn

University of Arkansas at Little Rock Law Review

No abstract provided.

Top Ten Issues In De-Spac Securities Litigation, Wendy Gerwick Couture

University of Arkansas at Little Rock Law Review

I am delighted to contribute to this symposium on special purpose acquisition companies (SPACs). The securities litigation associated with the de-SPAC transaction is at an early stage, but courts are already wrestling with a number of unsettled issues that cast a mirror on SPACs and the securities laws more broadly. As these issues are resolved, they will affect the future of de-SPAC transactions as well as the regulatory environment in which they operate. In this essay, I identify ten such issues, drawing from the pleadings, briefings, and hearings in pending de-SPAC securities cases, with the goal of highlighting the key …

Spac Regulation—Past, Present And Future, E. Ramey Layne, K. Stancell Haigwood

University of Arkansas at Little Rock Law Review

No abstract provided.

Civil Rights Law—Preserving Female Athletics: Arkansas’S Fairness In Women’S Sports Act, Chandler Little Bray

University of Arkansas at Little Rock Law Review

No abstract provided.

Pilot Testing A Survey To Evaluate Horse Owner And Trainer Perceptions Of The Importance And Ideality Of Equine Hoof Balance, Katherine Gilmore

Animal Science Undergraduate Honors Theses

Balance plays an integral role in the healthy equine hoof, yet there is a significant deficiency of research investigating horse owner and trainer knowledge of hoof balance. This study aimed to pilot test an online survey instrument evaluating horse owner and trainer perceptions of proper hoof care and balance. The survey instrument sought to collect demographic information of horse owners and trainers, determine horse owners’ and trainers’ abilities to identify ideally balanced equine forehooves, and assess horse owner and trainer knowledge of best hoof trimming and shoeing practices. Ninety-one horse owners and trainers with facilities that were within a 150-mile …

When Uncle Sam Spills: A State Regulator’S Guide To Enforcement Actions Against The Federal Government Under The Clean Water Act, Ian M. Staeheli

Washington Law Review

The U.S. government is one of the largest polluters on the planet. With over 700 domestic military bases and countless more federal facilities and vessels operating within state borders, there exists an enormous potential for spills and discharges of pollutants into state waters. The regulatory burden for enforcing environmental laws against the federal government falls on the Environmental Protection Agency and state regulators. But enforcing laws and regulations against the federal government and its progeny is a daunting regulatory task.

Other scholarship addresses some of the vexing peculiarities involved when regulating Uncle Sam. Those works discuss the “confusing mess” that …

Textualism's Immigration Problem: Stabilizing Interpretive Rules On Noncitizens' Rights And Remedies, Peter Margulies

Hofstra Law Review

The article focuses on textualism immigration problem as the U.S. Supreme Court has applied textualist methodology in immigration cases and misread the Immigration and Nationality Act (INA). It mentions application of linguistic canons occurs in a comparative, probabilistic assessment to resolve conflicts and analysis of statutory interpretation generally and immigration law in particular. It also mentions discusses inconsistencies in multi-member tribunals, such as appellate courts.

Circadian Genes In, Ewd-8, Triple-Negative Breast Cancer Cells May Demonstrate Rhythmicity In Vitro, Kayla Garza

Undergraduate Honors Theses

Studies have shown a link between greater rates and risks of breast cancer in women that work night shifts, such that this type of work has been labeled a probable carcinogen. It has been suggested that the disruption of circadian genes- PER and CRY - could be partly responsible for this increased breast cancer risk. The suprachiasmatic nucleus (SCN) in the brain is the central circadian pacemaker; however, how and if Triple-negative breast cancer (TNBC) cells, an aggressive type of breast cancer that is characterized by the absence of estrogen receptors (ER), progesterone receptors (PR), as well as HER-2 growth …

Misinformation Of Mental Health On Social Media And How It Affects Those Who View It, Kathryn Johnson

Undergraduate Honors Theses

Social media’s prevalence has grown through the years with 4.63 billion users around the world as of January 2022 (Global Social Media Stats). With the prevalence of social media, the question of the information, or in this case, the misinformation, that is on media platforms, especially about mental health, is one that needs to be brought to light. Mental health issues and disorders have become more of an open topic recently, and with the outreach on social media around mental health, the spread of misinformation can reach many audiences. This study analyzes just how potent the misinformation on mental health …

Increasing Collaboration And Knowledge In School Communities To Enhance Outcomes For Autistic Students, Amy Jane Griffiths, Diana Baker, John Brady, Kelly Kennedy, Anaiza Valladolid, Rachel Wiegand, Raquel Delgado

Education Faculty Articles and Research

Purpose

This paper describes a case study of a developmental program evaluation on the Autism Community Toolkit, a collaborative skills training program for parents and school professionals. The purpose of this study was to examine the influence of the training on participants’ knowledge, competence and perceived collaboration; and potential improvements to the training program.

Design/methodology/approach

The program included multiple training sessions for families and school professionals, designed to educate participants on autism, evidence-based interventions and to increase home-school communication and collaboration. Data collection methods included pre- and post-measures and feedback forms.

Findings

Results indicated that the training program was beneficial …

Characterization Of An Amine-Thiol Cosolvent System : Ethylenediamine And Mercaptoethanol, Fernanda Giongo Fernandes

Legacy Theses & Dissertations (2009 - 2024)

Since its introduction, the amine-thiol cosolvent system has been successfully utilized for the deposition of various thin-film devices, but its mechanism of action is still uncertain. Herein, we have attempted to dissect some of the chemical characteristics of amine-thiol cosolvents, with a special interest taken towards a mixture of ethylenediamine (en) and mercaptoethanol (ME). Conductivity was measured for multiple amine-thiol combinations at different ratios to determine extent of ionization in solution, with en-ME having one of the highest solution conductivities. Exposing the solution to air for several days was found to decrease the conductivity of en-ME, indicating the formation of …

Vircy-Seq : A Protocol For Characterizing Viral Activity, Tyler James Dion

Legacy Theses & Dissertations (2009 - 2024)

The main purpose of pharmaceutical production is to produce safe effective medicine for patient use. In an effort to ensure patient safety constant surveillance for viruses takes place. The detection of a viral nucleic acid in a pharmaceutical production setting results in investigations to assess its infectious potential. This is an intensive, expensive process that entails many tests such as the observation of hemadsorption, cytopathic effects (CPE), and more. These tests are typically specific and only capture certain viruses, as factors like CPE can only be observed in some viral species. A new investigational method that is effective on all …

Improving Detection And Classification Of Steady-State Visual Evoked Potentials In Brain-Computer Interfaces, Hadi Habibzadeh

Legacy Theses & Dissertations (2009 - 2024)

Brain-computer interfaces (BCIs) provide an alternative communication channel to send computer commands without requiring any voluntary muscle control. They benefit people with limited communication capabilities due to motor function deficits, spinal cord injuries, and neurological disorders. They may also have applications for healthy individuals.

Motion Planning Under Uncertainties, Sourav Dutta

Legacy Theses & Dissertations (2009 - 2024)

A robot is an agent that can bring some changes to the environment around it. Motion planning is the problem of carrying out specialized tasks by a robot by either moving itself or some other object (usually called \textit{payload}) from one place to another. In a real-world scenario, a robot is faced with constraints such as momentum, friction, sensor inaccuracies, etc., that can affect its decision-making while performing specialized tasks. These constraints are identified as uncertainties, and successful planning involves making provisions for such uncertainties. In this work, we present methods like stochastic processes, sequential inference, and pattern recognition to …

Interpersonal Forgiveness Is The Recognition That Justice Is Attained, Raphael Faith Moser

Legacy Theses & Dissertations (2009 - 2024)

Abstract

The Simulated Sensitivity Of The North American Monsoon At Convection-Permitting Scales, Brendan Wallace

Legacy Theses & Dissertations (2009 - 2024)

The North American Monsoon (NAM) is a major contributor to annual rainfall for large portions of the North American Southwest. Much of the prior work examining the NAM using numerical models has been done at scales exceeding 20-km grid spacing. At these coarse scales, unresolved processes and poorly resolved geographic features can impact model performance. This can present a problem when simulating the NAM particularly with regard to orographic precipitation, precipitation on sub-daily timescales, and land surface-atmosphere interactions. This dissertation seeks to better understand the NAM through examination of several sets of convection-permitting regional climate model output. The primary goal …

Spatio-Temporal Analyses Of The Relationships Between Stop, Question And Frisk And Crime In New York City, Haemi Won

Legacy Theses & Dissertations (2009 - 2024)

Previous research has shown mixed findings on a deterrent effect of Stop, Question and Frisk (SQF) on crime. As SQF is one of the most fundamental methods of police crime control, an accurate examination of the relationship between SQF and crime is critical. This dissertation examined spatio-temporal interactions of crime and those of SQF respectively, and then the spatial relationships between SQF and crime at microgeographic level, controlling for the effect of the street network. Using inhomogeneous cross K function with the exact location x-y coordinates of each point of both SQF and crime, this dissertation explored the spatio-temporal relationships …

Organic Gunshot Residue : Detection, Identification, And Characterization For Forensic Purposes, Shelby R. Khandasammy

Legacy Theses & Dissertations (2009 - 2024)

The major focus of this thesis was to explore methods for the detection, identification, and characterization of organic gunshot residues (OGSRs) for forensic purposes using various spectroscopic techniques. There are four major projects detailed in this thesis. The first project details the development of a novel-two step method for the detection and identification of organic gunshot residues using fluorescence spectroscopy for detection and Raman spectroscopy as a confirmatory step. The second chapter builds upon the study conducted in the first chapter by applying the novel-two step method covered in the first chapter to OGSRs directly fired into cloth substrates. This …

Soil From Footwear Is A Newly Rediscovered Type Of Forensic Evidence Due To The Application Of Modern Analytical Techniques : A Review, Rhilynn Haley Ogilvie

Legacy Theses & Dissertations (2009 - 2024)

Traces of soil discovered on a footwear were historically among the first types of evidence used by crime scene investigators. This type of evidence has been rediscovered recently due to the application of powerful analytical techniques providing quantitative characteristics of the soil (bio)chemical composition. Advanced statistical analysis of the quantitative data further improves the probative value of the soil evidence. The article overview main aspects of the emerging techniques for the forensic soil analysis and the factors that challenge data interpretation including mixing, contamination, and composition complexity. Overcoming these issues is crucial for utilizing soil analysis for forensic purposes.

Domain Aware Deep Learning For Wireless Physical Layer, Shuvam Chakraborty

Legacy Theses & Dissertations (2009 - 2024)

Wireless receiver design for OFDM systems is well investigated with classical signal processing tools, which lack the capacity to extract intrinsic channel effects in received signal and lead to high decoding error in receiver. Current deep learning techniques have shown improvement in such cases. But these models are mostly being developed as black box without any anchor to the theory of wireless signal propagation, which leads to surface level information gain and lacks generalizability. We propose deep learning models where the hyperparameters and learning objectives are derived from domain knowledge of wireless signal propagation. These models not only increase the …

Addressing Human Error Through Effective Cyber Policy Design, Katherine Amoresano

Emergency Preparedness, Homeland Security, and Cybersecurity

Human error is a significant contributing factor to the rise in Cybersecurity attacks regardless of increased technical control implemented to safeguard Information systems. Adversaries can circumvent technical safeguards due to human errors which result from inadequate enforceable policies and training on Cybersecurity for the everyday user. Several studies and articles show that the majority of successful attacks are human enabled, proving the need for human-centric cybersecurity research and practices. This exploratory work reviews the human aspect of Cybersecurity by investigating the cybersecurity policies at SUNY Albany and other SUNY institutions. We used a survey of students and faculty members at …

Analyzing Academic Self-Regulation Improvement Via Proccoli Task And Time Management Application, Le Jie Bennett

Computer Science

In the academic context, success is dependent on the individual’s ability to keep track of what needs to be done in a timely manner. But, for most students, procrastination often stands in their way. The time management application, Proccoli, is a tool that the Sahebi/Feyzi lab has developed to study individual and group procrastination behavior and help improve students’ ability to track and manage their tasks and time. Drawing foundations from Human Computer Interaction literature, the application provided features and functionalities to help promote selfregulatory behaviors such as self-observation, self-judgement, and self-reflection. An evaluation survey was sent to previous Proccoli …

Metabolic Alterations And Cardiovascular Risk After Hepatitis C Cure In Subjects With Or At Risk For Hiv, Christophe Maxime Fokoua Dongmo

Legacy Theses & Dissertations (2009 - 2024)

Background. Hepatitis C virus (HCV) infection engenders substantial metabolic changes. These changes are altered when the virus is cleared after successful treatment. We measured these metabolic alterations that occur after HCV cure; further, we assessed whether these alterations differed in subgroups defined by patients’ characteristics.

Turning Density Functional Theory Calculations Into Molecular Mechanics Simulations : Establishing The Fluctuating Density Model For Rna Nucleobases, Christopher A. Myers

Legacy Theses & Dissertations (2009 - 2024)

Molecular mechanics (MD) simulations and density functional theory (DFT) have been the backbone of computational chemistry for decades. Due to its accuracy and computational feasibility, DFT has become the go-to method for theoretically predicting interaction energies, polarizability, and other electronic properties of small molecules at the quantum mechanical level. Although less fundamental than DFT, molecular mechanics (MM) algorithms have been just as influential in the fields of biology and chemistry, owing their success to the ability to compute measurable, macroscopic quantities for systems with tens of thousands to hundreds of thousands of atoms at a time. Nevertheless, MD simulations would …

Probabilistic Forecasting Of Winter Mixed Precipitation Types In New York State Utilizing A Random Forest, Brian Chandler Filipiak

Legacy Theses & Dissertations (2009 - 2024)

Operational forecasters face a plethora of challenges when making a forecast; they must consider multiple data sources ranging from radar and satellites to surface and upper air observations, to numerical weather prediction output. Forecasts must be done in a limited window of time, which adds an additional layer of difficulty to the task. These challenges are exacerbated by winter mixed precipitation events where slight differences in thermodynamic profiles or changes in terrain create different precipitation types across small areas. In addition to being difficult to forecast, mixed precipitation events can have large-scale impacts on our society.