Digital Commons Network^™

Comparing The Academic Growth Among Black Students In Philadelphia’S Black-Operated Charter Schools, Non-Black Operated Charter Schools, And Traditional Public Schools., Cherryann M. Joseph

Doctoral Dissertations and Projects

This ex post facto, causal-comparative quantitative study assessed the math and English language arts (ELA) 7th to 8th-grade academic growth among Black students enrolled in Philadelphia’s black-operated public charter schools, non-black operated charter schools, and traditional public schools while controlling for 6th-grade exam scores. Over 65 years after Brown versus Board of Education disallowed public school segregation, the academic achievement gap between Black and white students persists. Various parental and educational stakeholders have considered charter public schools as suitable educational alternatives for narrowing this academic gap. This condition along with an assertion by some community activists that Black leaders are …

Characteristics That Make An Excellent Worship Leader According To The Perspectives Of Baptist Congregants In North Texas, Carlos Jerome Benson

Masters Theses

Despite many Baptists Churches in North Texas, most church congregants vary significantly in how they characterize an excellent worship leader. These congregants often rely on trial and error to establish characteristic traits that are acceptable for the whole of a particular church. There is a gap in the research study of characteristics that make an excellent worship leader according to the perspectives of Baptist congregants in North Texas. This study will find which attributes of worship leadership are most desirable according to the views of North Texas Baptist congregants. These literary examples do not specifically name what characteristics North Texas …

Final Revised Butte Reduction Works (Brw) Phase Iii Qapp, Nikia Greene

Silver Bow Creek/Butte Area Superfund Site

No abstract provided.

Surveilling Threat: The Roles Of Ideology And Threat Perceptions In Support For Islamophobic Policy, Aeleah M. Granger, Kimberly B. Kahn, Joel S. Steele

Psychology Faculty Publications and Presentations

After the attacks on 9/11, Muslims in the United States were the targets of increased surveillance by law enforcement on the basis of their religious identity, often resulting in mistreatment and unjustified imprisonment. The current study examined ideologies that are associated with Islamophobia and support for police surveillance of Muslims, as well as specific types of intergroup threat perceptions that mediate these relationships. Participants (N = 603) completed a survey measuring Social Dominance Orientation (SDO), Right-wing Authoritarianism (RWA), Nationalism, intergroup threat perceptions, Islamophobia, and support for an anti-Muslim police surveillance policy. Results demonstrated that higher levels of SDO, RWA, and …

Prophylaxis And Remediation For Future Pandemic Pathogens-(Lessons From A Post-Covid World), Mark E. Obrenovich, Moncef B. Tayahi, Caryn L. Heidt, Steven N. Emancipator

Michigan Tech Publications, Part 1

Since influenza and coronaviruses are currently deadly and emerging threats worldwide, better treatment, remediation and prevention options are needed. In that regard, a basic understanding of severe acute respiratory syndrome (SARS)-CoV-2/COVID-19 () and other viral pathogen mechanisms of transmission are expected. Unfortunately, unprecedented, and growing distrust of vaccines and even masks or personal protective equipment (PPE) in the United States and elsewhere presents itself as an added challenge. We postulate that development of improved and highly effective prophylactic measures, together with new life-saving therapies that do inhibit or otherwise treat infection of SARS-CoV-2, influenza and other viral pathogens, could be …

An Education Intervention Project In Community Clinics To Improve The Identification Of Patients With Pulmonary Alveolar Proteinosis And To Correctly Identify The Type Utilizing The Differential Diagnostic Algorithm, Catherine J. Poisson

Doctoral Dissertations and Projects

With over 7000 types, rare diseases affect 25-30 million Americans and contribute to over one trillion dollars in healthcare-related costs. Prescribers lack the knowledge to improve awareness, identification, and treatment of rare diseases. Pulmonary alveolar proteinosis is a rare disease in which patients present with symptoms such as dyspnea, fatigue, and respiratory infections. Diagnosis can take four to 92 months. A differential diagnostic algorithm published in the literature can guide clinicians in identifying the type of pulmonary alveolar proteinosis the patient has. In addition, if the clinicians perform a laboratory test called the granulocyte-macrophage autoantibody test, this test provides 100% …

Implementation Of Provider Education Regarding Exercise As Adjunctive Treatment For Common Mental Health Diagnoses, Lauren Grace Martin

Doctoral Dissertations and Projects

Mental and physical health are inextricably linked. The advent of the Covid-19 pandemic reduced physical activity levels while worsening mental health symptoms. Pharmacological treatments are frequently used to treat mental health conditions; however, side effects can worsen metabolic issues. There is significant evidence that exercise can improve mental health conditions. The purpose of this project was to utilize provider education as an intervention to increase the use of exercise as an adjunctive treatment in the psychiatric treatment plan. This project was implemented at Nevada Mental Health, an outpatient behavioral health clinic in Las Vegas, Nevada. The investigator conducted a chart …

The Consistency Of The Kingdom Of God Through Israel's Unconditional Covenants, Myungwoo Kim

Doctoral Dissertations and Projects

The Bible consistently presents one common theme: the kingdom of God. Biblical theology focuses on God’s faithfulness, wisdom, and purpose in the process of redemption. The Old Testament expresses the firm belief that God will surely fulfill His covenants and reign forever. The Old Testament prophets believed that the Messiah would come for judgment and salvation. They consistently prophesied the birth and reign of the Messiah, which connects the Old and New Testaments. There is a continuity between the Old and New Testaments. The promises made to Israel in the Old Testament will be fulfilled for Israel, not the church. …

Beyond The Call Of Duty: Supererogation Towards An Apologetic Approach In The Us Navy, Donald Anthony Baker Iii

Doctoral Dissertations and Projects

Members of the US Navy subscribe to common values outlined in the Sailor’s Creed, a shared dictum of foundational ideals that burdens all persons within the organization to follow. Honor, courage, commitment, excellence, and fairness are explicit organizational values written therein that codify the standard values expected of all Sailors regardless of rank or other designators. For Christians serving in the US Navy, how can they present the tenets of the Gospel in a manner appropriate, and legal, for a professional, secular work environment such as the military but are consistent with the biblical imperative to give a defense of …

Implementing And Equipping A Fivefold Ministry With Theological Education To Defend And Uphold Biblical Doctrines In The Church, Kara Yvette Harris

Doctoral Dissertations and Projects

God instructed believers to put forth their best work to rightly handle His Word of truth (2 Tim 2:15). Unfortunately, God’s truth is under attack and has been polluted with false teaching and incorrect understanding of Scripture. It is incumbent on the local church to combat this problem of incorrect biblical teaching head-on. Therefore, this action research project aims to demonstrate that through proper theological training in the church, this problem will be remedied. This action research assumes that arming the local church with theological training will strengthen its core. To this aim, this research project included teaching five theological …

Leadership Culture: An Effective Leadership Strategy For Church Growth And Spiritual Maturity, Sikiru A. Asifatu

Doctoral Dissertations and Projects

In every organization, leadership culture patterns require a constant assessment to ensure members adhere to corporate practices. In church settings, leadership culture not only creates change but also transforms ministry strategy. Often, church leaders do not perceive culture as the driving force behind effective ministry operations. At Gateway Church, the researcher encountered church growth issues that other ministries struggle with as well, from organizational structure to leadership style. These problems will continue to be a challenge unless the church reinvents an effective leadership strategy focusing on ministry development. This research aims to address the leadership development issue at Gateway Church …

God's Sovereignty - Our Peace In The Darkness, Marie Diane Peters

Doctoral Dissertations and Projects

This thesis action project utilizes a biblical understanding of God’s sovereignty to help Christians embrace God’s peace and stability as they navigate times of chaos and uncertainty. The goals are to identify unhealthy struggles through interviews that believers experienced during the COVID-19 pandemic, conduct a workshop that teaches a biblical understanding of God’s sovereignty, and assess its effectiveness for managing fear. After the workshop, participants showed an increased awareness of God’s sovereignty, personal ways knowledge of God’s sovereignty affected them, and how they would apply it during dark and challenging times. The results show that a greater understanding of God’s …

Teaching And Learning Music Technologically, Esteban Molina Cordovez

Doctoral Dissertations and Projects

Since the beginning of the Covid-19 pandemic, multimedia technology has transformed all educational paradigms. In this mixed-methods study, the researcher shows the effects of inspiring instructional technologies on assimilating musical knowledge and developing performance concepts. Thus, assisted- technology learning is the foundation of inspiration to induce music performance and theory, hardening self-esteem as the core subject of this study. The researcher measures time and skills gathered over two years by a group of high school music students, assessing them with two variables: first, traditional conservatory instruction, and second, the MusicLab method. In addition, the researcher quantifies how technological tools intervene …

Military Command Authority: A Phenomenological Study Of How U.S. Army Company-Grade Leaders Experience Insubordination, Thomas Woods Stone

Doctoral Dissertations and Projects

The purpose of this hermeneutic phenomenology is to explore the experiences of U.S. Army company commanders regarding insubordinate acts aimed at undermining their legitimate command authority. The theory guiding this dissertation is French and Raven’s (1959) theory of social power, which states that power is divided into five unique forms that leaders use in exercising their will to accomplish tasks. This study particularly considers the legitimate power base, a form of social power often asserted by virtue of holding an office or formal organizational position. The setting is an Army post in western United States; the study sample comprises three …

Addressing The Impact Of Adverse Childhood Experiences Of Adults Through The Pastoral Counseling Ministry Of Victory Church, Joseph Randall Tapp

Doctoral Dissertations and Projects

Dr. Vincent Filetti's landmark 1998 study exposed the impact of adverse childhood experiences (ACEs) on children and adults. His analysis determined that childhood traumatic experiences could strongly correlate to serious health issues in adults. Exposure to childhood adversity has been shown to correlate not only with mental health issues such as depression, suicide, and substance abuse but also with chronic, life-threatening health issues such as cardiovascular disease, diabetes, cancer, and immune system issues. This DMin study aims to address the impact of ACEs on adult clients of the pastoral counseling ministry of Victory Church, a large non-denominational Christian church located …

Exploring The Impact Of Generational Trauma On Mother-Daughter Relationships With An Emphasis On The African American Community, Bernadette Denise Ward

Doctoral Dissertations and Projects

In many communities the mother-daughter relationship is not only vital in the younger years but also in the teen and young adult years. Several studies have explored a mother’s influence on her daughter’s views of the self, others, and the world in general. The mother-daughter relationship does not only impact personal morals and values but also the types of relationships the daughters gravitate to. In the African American community, many of the mother-daughter relationships are known to be similar in nature and/or dynamics throughout generations. Relationships that are tainted or known as toxic also seem to cycle throughout several generations. …

Vbc Young Families Initiative, Andrew Ryan Scoggins

Doctoral Dissertations and Projects

This research project is designed for Victory Baptist Church in Weatherford, Texas, to reach young families. The purpose is to design and implement a plan that educates, equips, and engages individual church members to evangelize young families in Weatherford. The necessity of this research is evident in the face of consequences surrounding the past three years involving the pandemic and a leadership change at VBC. The intervention is mobilizing the members of VBC to reach young families. This mobilization centers around training the membership to reach young families. Using surveys and questionnaires with the membership reveals what are the thoughts …

Implicit Bias In The U.S. Air Force Criminal Justice System And The Excessive Punishment Of Black Airmen, Brandon Lanier Dinkins

Doctoral Dissertations and Projects

The purpose of this hermeneutic phenomenological study was to understand whether implicit bias influenced disproportionate commander-imposed punishment of junior ranking Black Airmen from grades E1–E4 who previously served on active duty in the U.S. Air Force. The theory guiding this study is the implicit bias theory introduced by psychologists Mahzarin Banaji and Anthony Greenwald in 1995. This theory identifies that attitudes, perceptions, and stereotypes shape specific groups' associations and qualities, which can influence decisions. This qualitative study employed a hermeneutic phenomenology research design. This study used snowballing and purposeful sampling methods to recruit 16 participants. Data within this study was …

Preexilic Traits Of The Israelian Prophetic Material In The Book Of Kings, Erik Kirk Divietro

Doctoral Dissertations and Projects

There are three primary objections to accepting the prophetic materials of the Book of Kings as historically contemporary with the events they purport to record. First, there is a theological bias against the supernatural character of the materials. These supernatural passages are categorized as folklore and legend. Many critics reject the historicity of supernatural events for a variety of reasons. The second objection is that the linguistic profile of the materials is late, dating from a period long after the events recorded and therefore has, at the least, been through so many redactions and emendations as to be unreliable. Third, …

Jus Post Bellum And The Augustinian Worldview, Edward Anthony Herty

Doctoral Dissertations and Projects

Augustine of Hippo wrote a great deal regarding the subject of state-sponsored armed conflict. His views have been categorized into the concepts of jus ad bellum, jus in bello, and, more recently, jus post bellum. Jus ad bellum and jus in bello address the moral responsibilities of a nation and its sovereign as the decision to enter into conflict is made and as agents of the state endeavor to keep human suffering to a minimum. Jus post bellum is a more recent ideal that has, since World War I, addressed the need to establish a long-lasting peace upon the conclusion …

Tanf Work Policy Influences On Family Behaviors And Child Development, Robert William Sturgill Jr

Doctoral Dissertations and Projects

There has been a lack of research on how work participation policies have impacted child development through their influences on family decisions. The purpose of this qualitative research study was to explore the perspectives of families toward TANF work participation policies, discover how those policies have influenced family behaviors, and analyze how those policy-behavior phenomena have impacted child development. First, the literature review showed that families with chronic welfare dependency had negative impacts on child development. The research showed that when TANF work participation policies were unenforced or income limits were too low, some recipients worked less and persisted in …

Pyridine Modifications Regulate The Electronics And Reactivity Of Fe–Pyridinophane Complexes, Magy A. Mekhail, Kristof Pota, Sugam Kharel, David M. Freire, Kayla N. Green

Biology, Chemistry, and Environmental Sciences Faculty Articles and Research

12-Membered pyridinophanes are the focus of many studies as biological mimics, chelators, and catalytic precursors. Therefore, the desire to tune the reactivity of pyridinophanes to better control the applications of derivative metal complexes has inspired many structure–activity relationship studies. However, the separation of structural versus electronic changes imparted by ligand modification has made these structure–activity relationship studies of transition metal catalysts challenging to define. In this work we show that 4-substitution of the pyridine ring in 12-membered tetra-aza pyridinophanes successfully provides a regulatory handle on the electronic properties of the metal center and, therefore, the catalytic C–C coupling activity of …

Translating Big Data To Clinical Outcomes In Anxiety: Potential For Multimodal Integration, Parmis Khosravi, André Zugman, Paia Amelio, Anderson M. Winkler, Daniel S. Pine

School of Medicine Publications

Purpose of the Review

This review describes approaches to research on anxiety that attempt to link neural correlates to treatment response and novel therapies. The review emphasizes pediatric anxiety disorders since most anxiety disorders begin before adulthood.

Recent Findings

Recent literature illustrates how current treatments for anxiety manifest diverse relations with a range of neural markers. While some studies demonstrate post-treatment normalization of markers in anxious individuals, others find persistence of group differences. For other markers, which show no pretreatment association with anxiety, the markers nevertheless distinguish treatment-responders from non-responders. Heightened error related negativity represents the risk marker discussed in …

Federated Learning Enables Big Data For Rare Cancer Boundary Detection, Sarthak Pati, Pamela Lamontagne, Daniel Marcus, Et Al.

2020-Current year OA Pubs

No abstract provided.

How Police Chaplains Can Facilitate Building And Maintaining Trust With Law Enforcement: Through The Ministry Of Presence, Marjorie Abrahams Dent

Doctoral Dissertations and Projects

CPP Chaplaincy Corps is a ministry that provides spiritual, emotional, and mental support to its law enforcement personnel. Their function is to enhance the well-being and quality of life of the police officers as they serve and protect the citizens of their city, by offering a listening ear, a supportive presence, and providing individual pastoral care. This project seeks to determine if the newly organized CPP Chaplaincy Corps can be successful in facilitating the process of building trust with law enforcement through the Ministry of Presence and Pastoral Care. It also documents the progress and changes that have been made …

Improving Lay Helper Effectiveness: Teaching Living Prayer As A Gateway To A Focused Kingdom Lifestyle, Mark R. Painter

Doctoral Dissertations and Projects

It is common for those entering counseling at the Lake Church Counseling Center to lack intimacy with God. When one lacks intimacy with God, they are in imminent danger of becoming influenced exclusively by the world's thinking in one or more areas of life. It is the effort of the LCCC to provide services to those suffering from emotional, spiritual, relational, and personal development struggles. Initially, the counseling center treats such conditions using Living Prayer to help clients strengthen their connection with God and transition to behaviors influenced only by the kingdom of God. This project aims to help Lake …

Older Adults And Digital Technology For Worship Service During A Pandemic At Saint Paul's Baptist Church In Richmond, Virginia, Donnie Lewis Smith

Doctoral Dissertations and Projects

The COVID-19 pandemic has caused the church to move from in-person worship to digital, online, and virtual worship services. This thesis project aims to determine if going to an alternative worship platform has presented problems for the elderly and senior Saint Paul’s Baptist Church members. Because of the large number of seniors at Saint Paul’s, the church’s leadership must be ready to help in any way to ensure that all members can participate in worship services during these unprecedented times. Since there is no projected timetable for when and if the church will return to worship services as we know …

Federated Learning Enables Big Data For Rare Cancer Boundary Detection, Sarthak Pati, Ujjwal Baid, Brandon Edwards, Micah Sheller, Shih-Han Wang, G Anthony Reina, Patrick Foley, Alexey Gruzdev, Deepthi Karkada, Christos Davatzikos, Chiharu Sako, Satyam Ghodasara, Michel Bilello, Suyash Mohan, Philipp Vollmuth, Gianluca Brugnara, Chandrakanth J Preetha, Felix Sahm, Klaus Maier-Hein, Maximilian Zenk, Martin Bendszus, Wolfgang Wick, Evan Calabrese, Jeffrey Rudie, Javier Villanueva-Meyer, Soonmee Cha, Madhura Ingalhalikar, Manali Jadhav, Umang Pandey, Jitender Saini, John Garrett, Matthew Larson, Robert Jeraj, Stuart Currie, Russell Frood, Kavi Fatania, Raymond Y Huang, Ken Chang, Carmen Balaña, Jaume Capellades, Josep Puig, Johannes Trenkler, Josef Pichler, Georg Necker, Andreas Haunschmidt, Stephan Meckel, Gaurav Shukla, Spencer Liem, Gregory S Alexander, Joseph Lombardo, Joshua D Palmer, Adam E Flanders, Adam P Dicker, Haris I Sair, Craig K Jones, Archana Venkataraman, Meirui Jiang, Tiffany Y So, Cheng Chen, Pheng Ann Heng, Qi Dou, Michal Kozubek, Filip Lux, Jan Michálek, Petr Matula, Miloš Keřkovský, Tereza Kopřivová, Marek Dostál, Václav Vybíhal, Michael A Vogelbaum, J Ross Mitchell, Joaquim Farinhas, Joseph A Maldjian, Chandan Ganesh Bangalore Yogananda, Marco C Pinho, Divya Reddy, James Holcomb, Benjamin C Wagner, Benjamin M Ellingson, Timothy F Cloughesy, Catalina Raymond, Talia Oughourlian, Akifumi Hagiwara, Chencai Wang, Minh-Son To, Sargam Bhardwaj, Chee Chong, Marc Agzarian, Alexandre Xavier Falcão, Samuel B Martins, Bernardo C A Teixeira, Flávia Sprenger, David Menotti, Diego R Lucio, Pamela Lamontagne, Daniel Marcus, Benedikt Wiestler, Florian Kofler, Ivan Ezhov, Marie Metz, Rajan Jain, Matthew Lee, Yvonne W Lui, Richard Mckinley, Johannes Slotboom, Piotr Radojewski, Raphael Meier, Roland Wiest, Derrick Murcia, Eric Fu, Rourke Haas, John Thompson, David Ryan Ormond, Chaitra Badve, Andrew E Sloan, Vachan Vadmal, Kristin Waite, Rivka R Colen, Linmin Pei, Murat Ak, Ashok Srinivasan, J Rajiv Bapuraj, Arvind Rao, Nicholas Wang, Ota Yoshiaki, Toshio Moritani, Sevcan Turk, Joonsang Lee, Snehal Prabhudesai, Fanny Morón, Jacob Mandel, Konstantinos Kamnitsas, Ben Glocker, Luke V M Dixon, Matthew Williams, Peter Zampakis, Vasileios Panagiotopoulos, Panagiotis Tsiganos, Sotiris Alexiou, Ilias Haliassos, Evangelia I Zacharaki, Konstantinos Moustakas, Christina Kalogeropoulou, Dimitrios M Kardamakis, Yoon Seong Choi, Seung-Koo Lee, Jong Hee Chang, Sung Soo Ahn, Bing Luo, Laila Poisson, Ning Wen, Pallavi Tiwari, Ruchika Verma, Rohan Bareja, Ipsa Yadav, Jonathan Chen, Neeraj Kumar, Marion Smits, Sebastian R Van Der Voort, Ahmed Alafandi, Fatih Incekara, Maarten M J Wijnenga, Georgios Kapsas, Renske Gahrmann, Joost W Schouten, Hendrikus J Dubbink, Arnaud J P E Vincent, Martin J Van Den Bent, Pim J French, Stefan Klein, Yading Yuan, Sonam Sharma, Tzu-Chi Tseng, Saba Adabi, Simone P Niclou, Olivier Keunen, Ann-Christin Hau, Martin Vallières, David Fortin, Martin Lepage, Bennett Landman, Karthik Ramadass, Kaiwen Xu, Silky Chotai, Lola B Chambless, Akshitkumar Mistry, Reid C Thompson, Yuriy Gusev, Krithika Bhuvaneshwar, Anousheh Sayah, Camelia Bencheqroun, Anas Belouali, Subha Madhavan, Thomas C Booth, Alysha Chelliah, Marc Modat, Haris Shuaib, Carmen Dragos, Aly Abayazeed, Kenneth Kolodziej, Michael Hill, Ahmed Abbassy, Shady Gamal, Mahmoud Mekhaimar, Mohamed Qayati, Mauricio Reyes, Ji Eun Park, Jihye Yun, Ho Sung Kim, Abhishek Mahajan, Mark Muzi, Sean Benson, Regina G H Beets-Tan, Jonas Teuwen, Alejandro Herrera-Trujillo, Maria Trujillo, William Escobar, Ana Abello, Jose Bernal, Jhon Gómez, Joseph Choi, Stephen Baek, Yusung Kim, Heba Ismael, Bryan Allen, John M Buatti, Aikaterini Kotrotsou, Hongwei Li, Tobias Weiss, Michael Weller, Andrea Bink, Bertrand Pouymayou, Hassan F Shaykh, Joel Saltz, Prateek Prasanna, Sampurna Shrestha, Kartik M Mani, David Payne, Tahsin Kurc, Enrique Pelaez, Heydy Franco-Maldonado, Francis Loayza, Sebastian Quevedo, Pamela Guevara, Esteban Torche, Cristobal Mendoza, Franco Vera, Elvis Ríos, Eduardo López, Sergio A Velastin, Godwin Ogbole, Mayowa Soneye, Dotun Oyekunle, Olubunmi Odafe-Oyibotha, Babatunde Osobu, Mustapha Shu'aibu, Adeleye Dorcas, Farouk Dako, Amber L Simpson, Mohammad Hamghalam, Jacob J Peoples, Ricky Hu, Anh Tran, Danielle Cutler, Fabio Y Moraes, Michael A Boss, James Gimpel, Deepak Kattil Veettil, Kendall Schmidt, Brian Bialecki, Sailaja Marella, Cynthia Price, Lisa Cimino, Charles Apgar, Prashant Shah, Bjoern Menze, Jill S Barnholtz-Sloan, Jason Martin, Spyridon Bakas

Faculty, Staff and Student Publications

Although machine learning (ML) has shown promise across disciplines, out-of-sample generalizability is concerning. This is currently addressed by sharing multi-site data, but such centralization is challenging/infeasible to scale due to various limitations. Federated ML (FL) provides an alternative paradigm for accurate and generalizable ML, by only sharing numerical model updates. Here we present the largest FL study to-date, involving data from 71 sites across 6 continents, to generate an automatic tumor boundary detector for the rare disease of glioblastoma, reporting the largest such dataset in the literature (n = 6, 314). We demonstrate a 33% delineation improvement for the surgically …

The Free Press Vol. 54, December 12-05-2022, Kelly Ledsworth

Free Press, The

Art is More Than Just Art--The Job Shadow Program--Indigenous Peoples: How They've Been Impacted--FAFSA deadline around the corner--November 14th and 28th Student Senate Meetings

Impact Of International Travel And Diarrhea On Gut Microbiome And Resistome Dynamics, Manish Boolchandani, Kevin S Blake, Drake H Tilley, Miguel M Cabada, Drew J Schwartz, Sanket Patel, Maria Luisa Morales, Rina Meza, Giselle Soto, Sandra D Isidean, Chad K Porter, Mark P Simons, Gautam Dantas

2020-Current year OA Pubs

International travel contributes to the global spread of antimicrobial resistance. Travelers' diarrhea exacerbates the risk of acquiring multidrug-resistant organisms and can lead to persistent gastrointestinal disturbance post-travel. However, little is known about the impact of diarrhea on travelers' gut microbiomes, and the dynamics of these changes throughout travel. Here, we assembled a cohort of 159 international students visiting the Andean city of Cusco, Peru and applied next-generation sequencing techniques to 718 longitudinally-collected stool samples. We find that gut microbiome composition changed significantly throughout travel, but taxonomic diversity remained stable. However, diarrhea disrupted this stability and resulted in an increased abundance …