Digital Commons Network^™

Trib3 Mediates Fibroblast Activation And Fibrosis Though Interaction With Atf4 In Ipf, Lan Wang, Wenyu Zhao, Cong Xia, Zhongzheng Li, Weiming Zhao, Kai Xu, Ningdan Wang, Hui Lian, Ivan O Rosas, Guoying Yu

Faculty, Staff and Students Publications

Idiopathic pulmonary fibrosis (IPF) is a fatal interstitial lung disease characterized by fibroblast activation, excessive deposition of extracellular matrix, and progressive scarring; the pathogenesis remains elusive. The present study explored the role of Tribbles pseudokinase 3 (TRIB3), a well-known stress and metabolic sensor, in IPF. TRIB3 is down-regulated in the lungs of IPF patients in comparison to control subjects. Deficiency of TRIB3 markedly inhibited A549 epithelial cells’ proliferation and migration, significantly reducing wound healing. Conversely, overexpression of TRIB3 promoted A549 cell proliferation and transmigration while it inhibited its apoptosis. Meanwhile, overexpressed TRIB3 inhibited fibroblast activation and decreased ECM …

Modern And Information Services Of An Academic Library: An Overview, Bala Sankar B, Bala Sankar B

Library Philosophy and Practice (e-journal)

Academic libraries are considered a confidence centre of educational establishments and their Services assist numerous academic programs, including teaching and research. In academic libraries, the application of the latest technology, particularly internet technology, has transformed traditional methods of providing library and information services. Introducing novel information via a variety of channels requires an extra need for information and a library system to include the latest users. As users of technology became more demanding, libraries grew or invented new services. Information methods and techniques are constantly being developed by the internet for libraries to use to provide their services. Some research …

Idaho Public Land Access: Amending Road Laws To Ensure Public Land Remains Accessible, Jillian Greene

Idaho Law Review

No abstract provided.

Natural Resource Policy And Collaborative Processes, Crystal M. Callahan, Katherine E. Himes

Idaho Law Review

No abstract provided.

Development Of Directed Randomization For Discussing A Minimal Security Architecture, Henrique Oyama, Dominic Messina, Keshav Kasturi Rangan, Akkarakaran Francis Leonard, Kip Nieman, Helen Durand, Katie Tyrrell, Katrina Hinzman, Michael Williamson

Chemical Engineering and Materials Science Faculty Research Publications

Strategies for mitigating the impacts of cyberattacks on control systems using a control-oriented perspective have become of greater interest in recent years. Our group has contributed to this trend by developing several methods for detecting cyberattacks on process sensors, actuators, or both sensors and actuators simultaneously using an advanced optimization-based control strategy known as Lyapunov-based economic model predictive control (LEMPC). However, each technique comes with benefits and limitations, both with respect to one another and with respect to traditional information technology and computer science-type approaches to cybersecurity. An important question to ask, therefore, is what the goal should be of …

Indicadores De Sustentabilidad Vba Mesmis, Geovanny Andres Martinez Jimenez

Ciencias Administrativas, Económicas y Contables

El presente libro se ha diseñado con el propósito de que el lector tenga una experiencia satisfactoria al momento de emplear los indicadores VBA MESMIS. Por tanto, el documento se estructura de manera minuciosa en dos apartados; el primero que trata acerca de los criterios de diagnóstico, en el que se plantea un ejemplo con información de tres unidades productivas, con el fin de i) desarrollar los indicadores correspondientes a los criterios; ii) conocer el nivel de desempeño de los indicadores; iii) realizar un análisis general y proponer recomendaciones para el fortalecimiento de la sustentabilidad de las unidades productivas; en …

Re-Engaging Students In Art History: An Action Research Study, Jenna Hermann

Art 895 Research Papers

In this action research study, I examine different ways to re-engage students in the study of art history. Due to the COVID-19 pandemic, I sought out more effective and exciting ways to integrate technology when teaching art history to my eighth-grade students. I implement studentled learning strategies as students explore The Met’s website, focusing on the 1900-Present virtual exhibition. I consider if and how this virtual learning platform does or does not make learning about art history more engaging.

Modernist And Post-Modernist Paradigms: A Forged Art Education Curriculum, Raelissa Hovelson

Art 895 Research Papers

The purpose of this study is to consider a curriculum that uses the best characteristics of both modernist and pos-tmodernist approaches to art education, and showcases artists that model the forged curriculum. A modernist approach to art education has students emulate the technical skills that has prevailed the Western culture of classical artists. A post-modernism approach is the idea that art education should be more about multiculturalism, social engagement, equity, diversity, and inclusion. Using a qualitative case study, a literature review is analyzed to understand both modernist and post-modernist paradigms. Through discussion, artists that model characteristics from both teaching approaches …

A Deep Look Into Languages And Research, Martha Isabel Diaz Ramirez, Francy Elena Martinez Franco, Rafael Leonardo Cortes Lugo, Marcela Diaz Ramirez, Rosa Delia Acosta, Helva Luz Palacios, Norma Constanza Durán Narváez, Gloria Milena Castellanos Mendoza, Angela Andrea Ariza Higuera, Ana Milena Morales Sossa, Adriana Paola Bendek, Adriana Carolina Torres Escobar, Alejandro Fernandez Benavides, Maria Elena Garassini Chávez, Hugo Mauricio Aldana Zárate, Diana Marcela Fúneme Estupiñan, Janneth Mercedes Mora Yate, Jhonatan Vásquez Guarnizo, Finn Ale Álvarez Contreras, Paola Ximena Romero Molina

Ciencias Sociales, Humanidades y Ciencias Políticas

RESUMEN: Investigue va más allá de las estadísticas y los números aislados. La investigación implica una indagación sistemática con una reflexión profunda para resolver problemas o enriquecer los conocimientos disponibles, en este caso las Humanidades incluyen una variedad ilimitada de ramas agrupadas en cinco áreas como son las artes, los idiomas, la literatura, la religión y la historia . Las humanidades ayudan a las comunidades a comprender el mundo en el que estamos inmersos y fomentan la formación de ciudadanos críticos. De hecho, las lenguas brindan herramientas para preservar la identidad y mejorar la calidad de vida en varias culturas …

2022 Fall - Commencement Program, Office Of The Registrar, East Tennessee State University

ETSU Commencement Ceremonies and Programs

No abstract provided.

Art Activism In The Elementary Art Classroom: A Case Study, Julian Kramer

Art 895 Research Papers

This research is focused on the integration of art activism into the elementary art curriculum. It begins with an overview of four contemporary artists known for their activist works. A review of recent literature related to art activism and art education follows. While there were many articles discussing art activism in art education curricula, integrating art activism at the elementary level is not well documented. It concludes with a discussion of these artists and the recent literature, with suggestions for age-appropriate activism-based art projects for elementary students.

Microplastic Accumulation In The Digestive Tract Of Young-Of-Year Atlantic Sharpnose Sharks (Rhizoprionodon Terraenovae) In The Grand Strand, Sc, Andrew Curtis Sitlinger

Electronic Theses and Dissertations

This study focused on the presence and accumulation of microplastic fibers in the digestive tract and livers of young-of-year Atlantic Sharpnose Sharks (Rhizopriondon terraenovae) from two sampling locations along the Grand Strand of South Carolina. R. terraenovae is a small, mesopredatory elasmobranch found abundantly along northwestern Atlantic Ocean coastlines. Thirty specimens of R. terraenovae were collected from May through August of 2020. Microplastics were found in all specimens. A total of 672 plastic particles were identified over the course of the study, with an average of 22.4 ± 10.5 (SD) plastics per specimen. The majority of the plastics were classified …

Next-Generation Sequencing Shows Increasing Temperatures Affect Stream Fungal Communities, Regan Hodgson

Electronic Theses and Dissertations

Under climate change predictions, surface air temperature is expected to continue to rise and will likely affect functioning of stream ecosystems and microbial communities. Aquatic hyphomycetes are key fungal decomposers of plant litter in headwater streams controlling carbon, energy, and nutrient flows to higher trophic levels. This project addressed the effects of temperature on stream fungal communities in two recently conducted experiments (microcosm and streamside channel studies) using Illumina sequencing. The objectives were to determine (1) if temperature affects community structure of stream fungi based on relative abundances of ITS2 rDNA sequences, (2) if the effects of temperature on aquatic …

Extraction, Analysis, And Comparison Of Microplastics In Sc Marsh Substrates, Austin G. Sige

Electronic Theses and Dissertations

The global, rapid increase in plastic production is a widespread problem for coastal environments such as marshes that present favorable conditions for plastic retention. This study looked at the microplastic abundance within three previously unstudied South Carolina marshes located in Myrtle Beach, Murrells Inlet, and Waties Island. A comparison between the microplastic types and abundances between locations provided knowledge about the impacts of sediment composition (sand, silt, clay, and organic matter) on microplastic sequestration. This study also produced a novel microplastic extraction methodology for cohesive marsh sediment that used elutriation to effectively break apart aggregates prior to chemical digestion and …

Improving Near Surface Refractivity Estimates In Marine Environments, Sarah Evelyn Wessinger

Electronic Theses and Dissertations

This study utilizes in-situ measurements and numerical weather prediction datasets collected during the Coupled Air-Sea Processes Electromagnetic Ducting Research East field campaign to assess how thermodynamic properties in the marine atmospheric surface layer influence evaporation duct shape and to develop a simple near-surface modified refractivity estimation method. This study utilizes a logarithmic linear parametric model, which describes evaporation ducts via three main parameters: evaporation duct height, evaporation duct curvature, and mixed layer slope. Notably, most studies utilizing this type of model assume the curvature, C0, to be a theoretical value derived assuming neutral atmospheric stability; a thermodynamic regime that is …

Habitat Use And Diel Movements Of Silver Carp Hypophthalmichthys Molitrix In Two Southeastern Reservoirs, Levi Umland

Honors College Theses

Bigheaded carp have spread rampantly throughout the Mississippi watershed and continue to spread by navigating through rivers, locks, and dams. The long-term effects these species will have on our ecosystems and natural resources is unknown. Their movements, behavior, and general seasonal patterns are well studied within rivers. However, their movements and behavior within reservoirs is poorly understood due to their initial numbers within reservoirs being lower than in rivers. To address this gap, I investigated the distribution and movement rates of Silver Carp within two reservoirs, Kentucky Reservoir and Barkley Reservoir, and possible correlative variables, including wind, temperature, residency, sex, …

Recolección Y Representación De Datos En Primero De Primaria Con Splash. Un Caso De Estudio, Carlos Javier González López, Martha Lidia Barreto Moreno, Felipe Eugenio Retamal Acevedo, Zandra Maritza Tarazona Carrascal, Lina Katerín Perea Zárate

Educación

La obra titulada Recolección y representación de datos en primera de primaria con Splash. Un caso de estudio. Es producto del proceso investigativo ejecutado en el marco de los proyectos titulados: Modelización computacional de hiperlugares móviles translocales.

Avanzando con el MEDIT hacia nuevos modelos educativos, y Observatorio Translocal de Calidad Educativa de la Universidad de Cundinamarca ¿ Fase II. El objetivo de este trabajo de grado es promover procesos de clasificación y organización de datos en los estudiantes de grado primero del gimnasio nuevo Bolívar, mediante la adaptación del software Splash como herramienta didáctica, para mejorar la comprensión en los …

Fabrication, Characterization, And Simulation Of Graphene-Copper Electrical Conductors, Raju Prasad Ghimire

Nanoscience and Microsystems ETDs

The addition of nanocarbons to copper (Cu), specifically in the form of graphene (GN), has been shown to enhance copper's properties. GN-Cu nanocomposites can potentially achieve higher electrical, mechanical, and thermal properties compared with copper. These characteristics make GN-Cu materials interesting for several applications including but not limited to interconnects, high voltage lines, and rotating machines. Copper’s microstructure and nanoscale interfacial phenomena between the GN and Cu control charge conduction in GN-Cu materials. In this work, we investigated the possibilities of conductivity enhancement in multi-layered GN-Cu composites both theoretically (classical, quantum, and atomistic models) and experimentally.

Additionally, our work elucidates …

Defective Proteostasis In Induced Pluripotent Stem Cell Models Of Frontotemporal Lobar Degeneration, Sidhartha Mahali, Rita Martinez, Melvin King, Anthony Verbeck, Oscar Harari, Bruno A Benitez, Kanta Horie, Chihiro Sato, Sally Temple, Celeste M Karch

2020-Current year OA Pubs

Impaired proteostasis is associated with normal aging and is accelerated in neurodegeneration. This impairment may lead to the accumulation of protein, which can be toxic to cells and tissue. In a subset of frontotemporal lobar degeneration with tau pathology (FTLD-tau) cases, pathogenic mutations in the microtubule-associated protein tau (MAPT) gene are sufficient to cause tau accumulation and neurodegeneration. However, the pathogenic events triggered by the expression of the mutant tau protein remain poorly understood. Here, we show that molecular networks associated with lysosomal biogenesis and autophagic function are disrupted in brains from FTLD-tau patients carrying a MAPT p.R406W mutation. We …

Low-Income New Hampshire Parents’ Food Acquisition Decisions, Sarah Boege, Jess Carson

Carsey Publications

Drawing on interviews with 16 low-income New Hampshire parents in 2022, this paper explores the complex decisions that families make in choosing what foods to buy and where (and how) to shop.

Investigating Applications Of Deep Learning For Diagnosis Of Post Traumatic Elbow Disease, Hugh James

McKelvey School of Engineering Graduate Student Theses & Dissertations

Traumatic events such as dislocation, breaks, and arthritis of musculoskeletal joints can cause the development of post-traumatic joint contracture (PTJC). Clinically, noninvasive techniques such as Magnetic Resonance Imaging (MRI) scans are used to analyze the disease. Such procedures require a patient to sit sedentary for long periods of time and can be expensive as well. Additionally, years of practice and experience are required for clinicians to accurately recognize the diseased anterior capsule region and make an accurate diagnosis. Manual tracing of the anterior capsule is done to help with diagnosis but is subjective and timely. As a result, there is …

Distribution And Soil Characteristics Associated With The Neches River Rose-Mallow (Hibiscus Dasycalyx), Morgan E. Langlinais

Electronic Theses and Dissertations

The Neches River rose-mallow, Hibiscus dasycalyx, is a rare herbaceous perennial endemic to East Texas. The threatened, obligate wetland species is currently at risk of being lost in the wild due to habitat loss, encroachment of nonnative and native plant species, and hybridization with two other Hibiscus congeners, Hibiscus laevis and Hibiscus moscheutos. Known locations of each of the three Hibiscus species were used to measure select soil characteristics and habitat variables associated with each of the rose-mallows. H. dasycalyx was concluded to be associated with more fertile soils and slightly more canopy coverage than H. laevis and …

Color Dependence Of The Topological Susceptibility In Yang-Mills Theories, Ed Bennett, Deog Ki Hong, Jong Wan Lee, C. J.David Lin, Biagio Lucini, Maurizio Piai, Davide Vadacchino

School of Engineering, Computing and Mathematics

For Yang-Mills theories in four dimensions, we propose to rescale the ratio between topologicalsusceptibility and string tension squared in a universal way, dependent only on group factors. We applythis suggestion to SU(Nc ) and Sp(Nc ) groups, and compare lattice measurements performed by severalindependent collaborations. We show that the two sequences of (rescaled) numerical results in these twofamilies of groups are compatible with each other. We hence perform a combined fit, and extrapolate tothe common large-Nc limit.

Applying Hls To Fpga Data Preprocessing In The Advanced Particle-Astrophysics Telescope, Meagan Konst

McKelvey School of Engineering Graduate Student Theses & Dissertations

The Advanced Particle-astrophysics Telescope (APT) and its preliminary iteration the Antarctic Demonstrator for APT (ADAPT) are highly collaborative projects that seek to capture gamma-ray emissions. Along with dark matter and ultra-heavy cosmic ray nuclei measurements, APT will provide sub-degree localization and polarization measurements for gamma-ray transients. This will allow for devices on Earth to point to the direction from which the gamma-ray transients originated in order to collect additional data. The data collection process is as follows. A scintillation occurs and is detected by the wavelength-shifting fibers. This signal is then read by an ASIC and stored in an ADC …

An Analysis Of New York State’S Bail Reform: Identifying And Addressing Gun Violence With The Give Executive Team, Hannah Hodge

Theses

In 2020, the New York legislature passed the bail reform law. The law included amendments to the Criminal Procedure Law (L 2019, ch 59, Part JJJ), eliminating cash bail and pretrial detention for non-violent crimes, and giving more guidance to judges setting bail (Rodriguez, 2022). Since the enactment of bail reform, there has been considerable debate concerning its impact on crime and violence. In spite of the ongoing debate about bail reform, few evaluations to date have ascertained bail reform’s impact on violence. The Monroe County Gun Involved Violence Elimination (GIVE) Executive Committee has commissioned the RIT Center for Public …

Product Liability Action: A Tooth To Strengthen Consumer Protection, Ashok R. Patil Prof. (Dr.)

International Journal on Consumer Law and Practice

As the world shifts to technological advancements, the advent of e-commerce marks its peak, particularly in India, where it has been earmarked as the fastest growing market with an annual growth rate of 51%. While these developments are an important part of globalization, a few challenges come along. Issues like unfair contracts, privacy, data protection, faulty goods, refund or return remained unaddressed as the earlier existing Consumer Protection Act, 1986 did not elucidate on the same. Given the above, the Law Commission of India had recommended that a separate law be enacted for better consumer protection. Based on the recommendations …

Legal Approaches To Liability Of Digital Platform Operators To Consumers, Dmitriy Kozhemyakin, Svetlana Mironova

International Journal on Consumer Law and Practice

This article is devoted to the consideration of approaches to the liability of digital platform operators to consumers. Given that the number of digital consumers who use goods (works, services) purchased using digital platforms is growing, it becomes necessary to define the concept and features of such platforms, determine the relationship between them, consumers and suppliers, as well as identify problems of legal liability of digital platforms. The article draws attention to the fact that despite the differences in the terminology used in legislation and literature (digital platforms, digital platform operators, aggregators, owners of aggregators, etc.), all of the above …

Crazy Old Bird Lady, Mary Kemp

Diamond Line Undergraduate Literary Magazine

Mary Beth Kemp is a senior English and Journalism major from Dallas, Texas. She loves writing, chai lattes, and aquariums.

Reconnecting With The Truth: Conspiracies, Perspective Taking, And Misinformation, Scott Sellnow-Richmond, Mili Pinski

Discourse: The Journal of the SCASD

“I’ve done my research.” Misinformation has become a prevalent topic in communication courses, particularly those focused on argumentation, public speaking, or even interpersonal and family communication. Students thus benefit from adapting public speaking-focused assignments to illuminate how to understand - and thus combat- disinformation in their own lives. This assignment works toward this goal in two stages, allowing students to argue not just against misinformation and conspiracies, but also to argue for them as an act of empathy and understanding. The applied nature of this exercise also empowers instructors with a way to concretely address this issue in the classroom. …

Diamond Line - Fall 2022, Diamond Line Editors

Diamond Line Undergraduate Literary Magazine

No abstract provided.