Digital Commons Network^™

Jephthah's Daughter: A Hebrew Foreground For Jesus' Passion In Matthew, Hanna Elizabeth Seariac

Theses and Dissertations

While there are key differences between Jephthah's daughter's story and that of Jesus, not least the difference in gender of the sacrificial victims, this thesis posits that both the similarities and differences between these two accounts can enrich readings of Jesus' death in the gospel of Matthew. A careful comparison of the narrative of Jephthah's daughter with Jesus' Passion narrative in the gospel of Matthew leads to the conclusion that Jesus' death should be interpreted as a human sacrifice. Reading Jesus' death as a human sacrifice and locating it in that socio-religious context makes his death indicative of a transactional, …

Increasing Student Engagement And Comprehension In The Elementary Classroom Through Text-Based Discussions, Lisa Newberry

Masters Projects

Research has illustrated that students are not performing at or above basic proficiency levels in reading. Several factors contribute to this lack of student achievement. Students need a comprehensive approach to understanding complex text, and teachers need assistance in facilitating this. Implementing a classroom discourse approach is an effective way to enable student engagement, build essential literacy skills, and promote reading comprehension to increase student academic achievement in all content areas. Currently, however, providing a discourse approach with fidelity has not been a top priority among stakeholders. Thus, this project focuses on the implementation of a professional development pilot program …

Illegal Homeless Encampments In California: Using The Com-B Framework To Transform A Public Health Nuisance Into A New Housing Development Model, Desiree E. Orozco

Master's Projects and Capstones

California has the highest homeless population, with over 161,000 people experiencing homelessness. Despite approving a billion dollars in grants for the 2018-2019 budget, The 2021 Annual Homeless Assessment Report (AHAR) to Congress revealed California had an increase of over 3,500 individuals staying in shelters between 2020-2021. The multi-faceted and multi-dimensional issues of homelessness and policies make it difficult to prevent individuals experiencing homelessness from living in illegal encampments. Therefore, the author proposes a multi-prong approach to homelessness in California grounded in theories of the Socio-Ecological Model (SEM) and COM-B model and informed by housing first and permanent supportive housing practices. …

Kim Bowes, Ed. The Roman Peasant Project 2009–2014: Excavating The Roman Rural Poor. Philadelphia: University Of Pennsylvania Museum Of Archaeology And Anthropology, 2021. Pp. 824. Hardcover (Isbn 9781949057072) $120.00., Mauro Puddu

New England Classical Journal

No abstract provided.

Foraging Habitat Selection Of Shrubland Bird Community In Tropical Dry Forest, Anant Deshwal, Steven L. Stephenson, Pooja Panwar, Brett A. Degregorio, Ragupathy Kannan, John D. Willson

Biological Sciences Faculty Publications and Presentations

Habitat loss due to increasing anthropogenic disturbance is the major driver for bird population declines across the globe. Within the Eastern Ghats of India, shrubland bird communities are threatened by shrinking of suitable habitats due to increased anthropogenic disturbance and climate change. The development of an effective habitat management strategy is hampered by the absence of data for this bird community. To address this knowledge gap, we examined foraging sites for 14 shrubland bird species, including three declining species, in three study areas representing the shrubland type of forest community in the Eastern Ghats. We recorded microhabitat features within an …

A Systematic Literature Review Of The Prevalence, Distribution, Exposure, And Human Health Risks Of Tire Microplastics And The Contribution Of Their Physicochemically Diverse Properties, Luke Glastad

Theses & Dissertations

The history of synthetic plastics dates back to their first uses in 1907, continues with their expansion through the middle of the century with a diverse array of new polymers, and are so omnipresent today that many label this age of Earth the Plasticene Era. Tire microplastics (TMPs) have been increasingly identified as one of the environment's most bountiful types of microplastics (MPs). TMPs mainly enter the environment as tire-wear particles (TWPs) and recycled tire crumb (RTC). TWPs, in particular, have a high degree of variability, which impacts their distribution, degradation, and risk for adverse human health effects. This review …

Dysregulation Of Mir-10a Promotes Cancer Features In Cholangiocarcinoma, Matthieu Spriet

Theses & Dissertations

Cholangiocarcinoma is a primary liver cancer of the bile duct epithelium that exhibits microRNA-mediated control of tumor cell signaling. Strides toward new treatment rest on a better defining of cholangiocarcinoma tumor biology including the RNA-based layer of regulation. Additionally, there is a gap in knowledge on microRNA expression in human tissue. While there is RNA-seq data of microRNA expression in tissue, it does not differentiate between cell types, thus leaving unanswered questions about cell specific microRNA biology and expression.

Here, we identify miR-10a as an oncogenic microRNA acting through MAPK signaling. Using cholangiocarcinoma cell lines, we determined miR-10a is an …

The Development And In Vivo Immunologic Assessment Of Biodegradable Microparticles Incorporating Cpdi-02 And Mucosal Protein Vaccine, Jacob E. Parriott

Theses & Dissertations

Encapsulation in biodegradable microparticles (MPs) is a promising approach to increase the efficacy of intranasally administered protein vaccines. The generation of long-lived adaptive immune responses against encapsulated protein vaccines, however, requires the incorporation of a suitable mucosal adjuvant. CPDI-02—a complement peptide-derived immunostimulant that selectively activates dendritic cells and macrophages over neutrophils while minimizing the inflammatory side effects of parent C5a—has previously been incorporated into both systemic and mucosal vaccine formulations via direct conjugation to chemical moieties, peptides, proteins, inactivated pathogens, and the surface of biodegradable particles, to enhance Th1-biased cellular immune responses. The effect of CPDI-02 surface conjugation to MPs …

Nine Out Of Ten Samples Were Mistakenly Switched By The Orang-Utan Genome Consortium, Graham L Banes, Emily D Fountain, Alyssa Karklus, Robert S Fulton, Lucinda Antonacci-Fulton, Joanne O Nelson

2020-Current year OA Pubs

The Sumatran orang-utan (Pongo abelii) reference genome was first published in 2011, in conjunction with ten re-sequenced genomes from unrelated wild-caught individuals. Together, these published data have been utilized in almost all great ape genomic studies, plus in much broader comparative genomic research. Here, we report that the original sequencing Consortium inadvertently switched nine of the ten samples and/or resulting re-sequenced genomes, erroneously attributing eight of these to the wrong source individuals. Among them is a genome from the recently identified Tapanuli (P. tapanuliensis) species: thus, this genome was sequenced and published a full six years prior to the species' …

Does Shrub Encroachment Reduce Foraging Grass Abundance Through Plant-Plant Competition In Lesotho Mountain Rangelands?, Meredith Root-Bernstein, Colin Hoag

Anthropology: Faculty Publications

Shrub encroachment is understood to be an important problem facing rangeland ecosystems globally. The phenomenon is still poorly understood both in regard to its impacts (e.g., on diversity, productivity, and soil properties) and its causes. We study the impacts and causes of dwarf shrub encroachment in the highlands of Lesotho. There, shrubs have been described as indicators of generalized land degradation and soil erosion. Surprisingly, our findings show that grass abundance is not reduced by shrub abundance, but that forb abundance does decrease with shrub abundance. We suggest that not enough research has been done to examine the role of …

Tennessee State Unintentional Drug Overdose Reporting System (Sudors) Report 2022, Tennessee. Department Of Health.

Drug Poisonings and Overdoses in Tennessee

No abstract provided.

Investigating The Role Of Splenic Macrophages In Pancreatic Cancer, Daisy V. Gonzalez

Theses & Dissertations

Pancreatic cancer is currently the 3rd leading cause of all cancer-related deaths, with a 5-year survival rate remaining at 10%. The current standard treatment of care and a lack of effective diagnostic markers leaves patients with a dismal prognosis at advanced stages of the disease. This thesis research evaluated the effect of ApoE-expressing macrophages in the spleen. First, we aimed to assess the ApoE expression in the spleen of pancreatic tumor-bearing mice. Results showed that ApoE expression in splenic macrophages increased as the disease progressed. In addition, we saw a significant increase in marginal zone metallophilic macrophages and red pulp …

Neuropilin-2 In Advanced Prostate Cancer And Its Targeting With Novel Small Molecule Inhibitors, Ridwan Islam

Theses & Dissertations

Despite the development of new therapies, clinical management of advanced metastatic castrationresistant prostate cancer (mCRPC) still remains challenging owing to the emergence of therapy resistance. Resistance to the therapies is driven by both AR and non-AR pathways. Non-AR pathway is characterized by a lineage switch that leads to the development of neuroendocrine-like (NE-like) prostate cancer (PCa), which has a fulminant clinical course due to the lack of effective treatment strategy. Therefore, novel molecular targets need to be identified to develop effective therapeutic regimen to improve the outcomes in advanced PCa patients including NE-like PCa. Recent investigation on advanced PCa patients …

Investigating The Role Of Sphingosine Kinases During Alphavirus Infection, Opeoluwa Oyewole

Theses & Dissertations

Several alphaviruses, critical human pathogens, have re-emerged in recent years. Alphaviruses are found on all continents and infect both invertebrates and vertebrates, including some aquatic animals. They are classified as arboviruses because hematophagous arthropods transmit them. Based on the symptoms they cause, alphaviruses are classified as either arthritogenic or encephalitic.

Rising global travel has led to outbreaks of infections in new regions, increasing the geographical ranges of alphaviruses and causing new infections in susceptible hosts. Currently, there are no approved prophylactic or therapeutic measures to prevent or treat alphavirus infections; prevention measures have focused on vector control. These measures are …

Warming Overcomes Dispersal-Limitation To Promote Non-Native Expansion In Lake Baikal, Larry L. Bowman Jr., Daniel J. Wieczynski, Lev Y. Yampolsky, David M. Post

ETSU Faculty Works

Non-native species and climate change pose serious threats to global biodiversity. However, the roles of climate, dispersal, and competition are difficult to disentangle in heterogeneous landscapes. We combine empirical data and theory to examine how these forces influence the spread of non-native species in Lake Baikal. We analyze the potential for Daphnia longispina to establish in Lake Baikal, potentially threatening an endemic, cryophillic copepod Epischurella baikalensis. We collected field samples to establish current community composition and compared them to model predictions informed by flow rates, present-day temperatures, and temperature projections. Our data and model agree that expansion is currently …

Painting As A Vehicle For Identity Formation And Survival, Chunbum Park

Theses

Through the thesis, I produce a highly rigorous body of works and explore the theoretical and philosophical reasons behind my paintings. I explore why I repeatedly paint myself as a woman and why the symbols of tigers, frogs, Frankenstein, and other aspects of Northeast Asian and Korean culture and heritage appear in my paintings. I find that painting is a process by which I can reflect on my own identity as a Korean who alternates between masculine and feminine identities. Painting allows me to react against the problems threatening my identity such as the worldwide trend of the racialization of …

Current Challenges In Image-Guided Magnetic Hyperthermia Therapy For Liver Cancer, Anirudh Sharma, Erik Cressman, Anilchandra Attaluri, Dara L Kraitchman, Robert Ivkov

Faculty, Staff and Student Publications

For patients diagnosed with advanced and unresectable hepatocellular carcinoma (HCC), liver transplantation remains the best option to extend life. Challenges with organ supply often preclude liver transplantation, making palliative non-surgical options the default front-line treatments for many patients. Even with imaging guidance, success following treatment remains inconsistent and below expectations, so new approaches are needed. Imaging-guided thermal therapy interventions have emerged as attractive procedures that offer individualized tumor targeting with the potential for the selective targeting of tumor nodules without impairing liver function. Furthermore, imaging-guided thermal therapy with added standard-of-care chemotherapies targeted to the liver tumor can directly reduce the …

A Thematic Review On Digital Storytelling (Dst) In Social Media, Ameer Fathima Musfira, Nurulhuda Ibrahim, Harryizman Harun

The Qualitative Report

Digital Storytelling (DST) is defined as telling stories using digital means. It has been initially applied for diverse purposes, including in community development, therapeutic benefits, and as an aid in teaching and learning. DST has recently been broadly used on social media platforms for marketing, running campaigns, journalism, and much more. However, no comprehensive systematic or thematic review of DST in social media has been conducted. Accordingly, this paper aims to provide a thematic review of DST in social media. The thematic review was carried out on 50 articles published from 2016 to 2021. These 50 discrete studies were selected …

Contextual Factors Impacting School And Pastoralist Family Communication In Rural Mongolia: A Partial Ecological Model, Batdulam Sukhbaatar Dr, Klara Tarko Dr

The Qualitative Report

This study developed a partial ecological model of contextual factors impacting school and pastoralist family communication at the primary school level in rural Mongolia based on Bronfenbrenner’s ecological model. To develop the model, we interviewed 10 classroom teachers and 10 pastoralist parents from two remote county schools in eastern Mongolia. During our interpretative phenomenological analysis based on semi-structured interviews, we found eight contextual factors impacting rural school and pastoralist family communication located at the exosystem and the macrosystem levels. The partial ecological model can be used in teacher education programs providing a greater insight into the contexts of school-family communication …

The Theory Of Reasoned Action As A Basis For Investment In Cryptocurrency, Wrr Rinaldo

Masters Theses, 2020-current

In the past decade and a half, emergent blockchain technology has gained widespread attention, especially in the past few years. For the most part, attention has been focused on cryptocurrencies, but non-fungible tokens (NFTs), that use similar technology, have been given attention as well. Many concerns about these technologies have arisen, particularly that of the environmental impacts associated with them. Utilizing the theory of reasoned action, diffusion of technology theory, and surveys conducted through Amazon Mechanical Turk, this research attempts to uncover if there is a link between the level of cryptocurrency knowledge that an individual possesses and the level …

Agrichemicals (Nitrate And Atrazine) In Drinking Water And Adverse Health Outcomes In Children In Nebraska, Balkissa S. Ouattara

Theses & Dissertations

Objectives: This research was conducted to (1) determine the concentrations of atrazine, and nitrate, in Nebraska watersheds and counties; (2) calculate the incidence of pediatric cancers and prevalence of birth defects in Nebraska counties and watersheds, respectively; (3) assess the relationship between the contaminant levels and the incidence rate of pediatric cancers and birth defects prevalence.

Methods: Pediatric cancers and birth defects data were obtained from the Nebraska Department of Health and Human Services. Water quality data were collected and retrieved from the Water Quality Portal and the Nebraska Groundwater Quality Clearinghouse. Geospatial and statistical analyses were conducted at the …

Regulation Of Microglial Activation In Stroke In Aged Mice: A Translational Study, Conelius Ngwa, Abdullah Al Mamun, Shaohua Qi, Romana Sharmeen, Yan Xu, Fudong Liu

Faculty, Staff and Student Publications

Numerous neurochemical changes occur with aging and stroke mainly affects the elderly. Our previous study has found interferon regulatory factor 5 (IRF5) and 4 (IRF4) regulate neuroinflammation in young stroke mice. However, whether the IRF5-IRF4 regulatory axis has the same effect in aged brains is not known. In this study, aged (18-20-month-old), microglial IRF5 or IRF4 conditional knockout (CKO) mice were subjected to a 60-min middle cerebral artery occlusion (MCAO). Stroke outcomes were quantified at 3d after MCAO. Flow cytometry and ELISA were performed to evaluate microglial activation and immune responses. We found aged microglia express higher levels of IRF5 …

Effects Of Net Type On The Quantification Of Pelagic Shrimp And Krill In The Gulf Of Mexico, Eric J. Lee

All HCAS Student Capstones, Theses, and Dissertations

Trawls are an effective and widely used method for collecting micronekton because they can sample large volumes of sparsely distributed organisms, as well as allow for direct species identification of collected samples. However, net sampling methods are known to be highly variable in terms of design and catchability, and comparisons of deep-sea trawl data from two different types of nets over the same spatial and temporal scale are relatively rare. The current study is unique because it provides such an analysis for micronektonic crustaceans in the Gulf of Mexico (GOM) by comparing the trawling efficacy of a smaller 10 m …

Size Structuring Of Myctophids In The Northern Gulf Of Mexico In The Years Following The Deepwater Horizon Oil Spill, Adam Warren

All HCAS Student Capstones, Theses, and Dissertations

Body size is one of the main determinants of marine ecosystem structure and is correlated with many behavioral processes such as diel vertical migration (DVM). Myctophidae, a highly abundant, speciose, and globally distributed fish family, perform diel vertical migrations between the epipelagic zone at night and the mesopelagic zone during the day with vertical distributions varying with ontogeny, and therefore body length. Understanding how DVM contributes to an ecosystem’s structure is important to understanding ecosystem functioning, especially in response to anthropogenic impacts such as the Deepwater Horizon oil spill. The aim of this study was to investigate changes in myctophid …

Post-Transcriptional Control Of The Epithelial-To-Mesenchymal Transition (Emt) In Ras-Driven Colorectal Cancers, Chaitra Rao

Theses & Dissertations

Colorectal cancer (CRC) originates from epithelial cells lining the colon or rectum of the gastrointestinal tract. Most cancer deaths result from a tumor spreading to distant organs; however epithelial cells do not normally migrate from their tissue of origin. To do so, epithelial cells undergo biochemical changes allowing them to acquire behavior similar to motile mesenchymal cells termed the epithelial-to-mesenchymal transition (EMT), which contributes to tumor invasion and metastasis. Our study demonstrated that CRC cells require a molecular scaffold, Kinase Suppressor of Ras 1 (KSR1), and ERK to promote the EMT-like phenotype through the preferential translation of Epithelial Stromal Interaction …

Chemical Castration: An Analysis Of Florida's New "Cutting-Edge" Policy Towards Sex Criminals, Bryan Keene

Florida Law Review

No abstract provided.

Herbal Remedies And Dietary Supplements: The Boundaries Of Drug Claims And Freedom Of Choice, Margaret Gilhooley

Florida Law Review

No abstract provided.

Not Just A Descending Trail: Traversing Holmes' Many Paths Of The Law, Winston P. Nagan

Florida Law Review

No abstract provided.

Alschuler's "Path", David Dolinko

Florida Law Review

No abstract provided.

When Paths Diverge: A Response To Albert Alschuler On Oliver Wendell Holmes, James Gordley

Florida Law Review

No abstract provided.