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2022

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Non-Christian, Japanese College Students’ Perspectives Of Engaging With God Through The Participatory Components Of Christian Worship, Jacqueline Leigh Bencke Dec 2022

Non-Christian, Japanese College Students’ Perspectives Of Engaging With God Through The Participatory Components Of Christian Worship, Jacqueline Leigh Bencke

Doctoral Dissertations and Projects

This study seeks to examine the extent to which non-Christian college students in Japan perceive their engagement with the biblical God while participating in daily chapel services at Kyūshū Lutheran College. The research employs a mixed-methods approach, analyzing survey and focus group data to explore whether a relationship exists between students’ participation in chapel committee activities and their perceived spiritual engagement. Responses to Lynn Underwood’s Daily Spiritual Experience Survey, the Centrality of Religiosity Scale, and the Centrality of Buddhist Religiosity Scale are combined to create a general spiritual profile of respondents. Worship leaders and missionaries who are in positions of …


The Jewish Basis For The Born Again Experience In John 3, Francis-David Athelstan Scalzo Dec 2022

The Jewish Basis For The Born Again Experience In John 3, Francis-David Athelstan Scalzo

Doctoral Dissertations and Projects

The dissertation’s objective will be to analyze what Nicodemus—as a Pharisee who was knowledgeable of the Hebrew Bible and the prevalent Jewish theology of his period—should have understood, given his position, concerning Jesus’ teaching of being born again. By examining the Old Testament (the TaNaK) and Intertestamental Jewish theology, it will be argued in the dissertation’s six chapters how Nicodemus, as a prominent Pharisaical religious instructor, should have understood the concept of spiritual rebirth as well as the scriptural significance of water and the Spirit, including the guidance and obedience inherent in Jesus’ teaching on the wind. As an introduction …


Let Them Be Little: A Transcendental Phenomenological Study Of The Experiences Of Kindergarten Teachers During An Era Of Educational Reform, Rachel Denise Whites Dec 2022

Let Them Be Little: A Transcendental Phenomenological Study Of The Experiences Of Kindergarten Teachers During An Era Of Educational Reform, Rachel Denise Whites

Doctoral Dissertations and Projects

The purpose of this transcendental phenomenological study was to understand the lived experiences and perceptions of kindergarten teachers who taught through an era of federally mandated, standards-based educational reforms. This study was guided by two theories as each contributes to an explanation as to how educational reform has strayed far from the central purpose for kindergartens. Piaget’s theory of cognitive development sought to explain how a child constructs a mental model of the world and postulated that there are four distinct stages of human development from birth to adulthood. Vygotsky’s sociocultural theory stated that children learn through play and the …


The Impact Of The Covid-19 Pandemic On Law Enforcement Protocols In Middle Appalachian States, Timothy W. Roberts Dec 2022

The Impact Of The Covid-19 Pandemic On Law Enforcement Protocols In Middle Appalachian States, Timothy W. Roberts

Doctoral Dissertations and Projects

The COVID-19 pandemic is changing the operational procedures of law enforcement organizations across the United States. The COVID-19 virus has forced police administrators to rethink strategies and procedures dealing with law enforcement’s multiple functions and roles in society. The pandemic is causing unprecedented challenges for law enforcement administrators to balance the organization’s priorities and the safety of officers under their command. The police functions are adapting to include personal protection to prevent the spread of the virus among the law enforcement community. This multiple case qualitative study aimed to show the immediate operational changes in law enforcement since the start …


Can The Unfree Be Held Morally Responsible? A Douglassonian Conception Of Freedom And Distributed Moral Agency, Abraham Singer Dec 2022

Can The Unfree Be Held Morally Responsible? A Douglassonian Conception Of Freedom And Distributed Moral Agency, Abraham Singer

School of Business: Faculty Publications and Other Works

Can those dominated and oppressed by racialized power structures be held responsible for their actions? On some plausible accounts of moral responsibility, the answer is “no”: domination exempts the oppressed from moral obligations because they are structurally deprived of the freedom to make choices for which one might be blameworthy. In this article, I use the work of Frederick Douglass to offer a different understanding of moral responsibility. Attending to specific arguments that Douglass makes regarding the moral responsibility of slaves, and the tensions it raises with other parts of his corpus, I argue that one's ability to act as …


The Importance Of Mitral Valve Prolapse Doming Volume In The Assessment Of Left Ventricular Stroke Volume With Cardiac Mri, Brendan K Podell, Omowunmi Aibana, Chuan-Chin Huang, James E Dilisio, Macallister C Harris, David F Ackart, Kody Armann, Alexander Grover, Patrice Severe, Marc Antoine Jean Juste, Kathryn Dupnik, Randall J Basaraba, Megan B Murray Dec 2022

The Importance Of Mitral Valve Prolapse Doming Volume In The Assessment Of Left Ventricular Stroke Volume With Cardiac Mri, Brendan K Podell, Omowunmi Aibana, Chuan-Chin Huang, James E Dilisio, Macallister C Harris, David F Ackart, Kody Armann, Alexander Grover, Patrice Severe, Marc Antoine Jean Juste, Kathryn Dupnik, Randall J Basaraba, Megan B Murray

Faculty, Staff and Student Publications

BACKGROUND: Although previous studies have shown that vitamin A deficiency is associated with incident tuberculosis (TB) disease, the direction of the association has not been established. We investigated the impact of vitamin A deficiency on TB disease progression.

METHODS: We conducted a longitudinal cohort study nested within a randomized clinical trial among HIV-infected patients in Haiti. We compared serial vitamin A levels in individuals who developed TB disease to controls matched on age, gender, follow-up time, and time to antiretroviral therapy initiation. We also evaluated histopathology, bacterial load, and immune outcomes in TB infection in a guinea pig model of …


Going Cold Turkey? Changes To Faunal Subsistence In The Northern San Juan Region From Basketmaker Ii Through Pueblo Iii, Tenaya Gatrell-Bedard Dec 2022

Going Cold Turkey? Changes To Faunal Subsistence In The Northern San Juan Region From Basketmaker Ii Through Pueblo Iii, Tenaya Gatrell-Bedard

Theses and Dissertations

Previous research in the Northern San Juan Region of the American Southwest has revealed a pattern of change in subsistence patterns from the Basketmaker II through Pueblo III periods. Jonathan C. Driver describes the pattern as: cottontail in Basketmaker III (500 to 750 CE) and Pueblo I (750 to 900 CE), deer in Pueblo II (900 to 1150 CE), and turkey in Pueblo III (1150 to 1350 CE). The transition from deer to turkey as the main subsistence has been recorded at several sites throughout the Northern San Juan Region and is thought to be caused by the overhunting of …


Covid-19 Induces Cns Cytokine Expression And Loss Of Hippocampal Neurogenesis, Allison L Soung, Abigail Vanderheiden, Xiaoping Jiang, Traci Bricker, Adrianus C M Boon, Robyn S Klein, Et Al. Dec 2022

Covid-19 Induces Cns Cytokine Expression And Loss Of Hippocampal Neurogenesis, Allison L Soung, Abigail Vanderheiden, Xiaoping Jiang, Traci Bricker, Adrianus C M Boon, Robyn S Klein, Et Al.

2020-Current year OA Pubs

Infection with the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is associated with acute and postacute cognitive and neuropsychiatric symptoms including impaired memory, concentration, attention, sleep and affect. Mechanisms underlying these brain symptoms remain understudied. Here we report that SARS-CoV-2-infected hamsters exhibit a lack of viral neuroinvasion despite aberrant blood-brain barrier permeability. Hamsters and patients deceased from coronavirus disease 2019 (COVID-19) also exhibit microglial activation and expression of interleukin (IL)-1β and IL-6, especially within the hippocampus and the medulla oblongata, when compared with non-COVID control hamsters and humans who died from other infections, cardiovascular disease, uraemia or trauma. In the …


Weight Of The Sword And The Hero's Journey, Chase Baylor Moore Dec 2022

Weight Of The Sword And The Hero's Journey, Chase Baylor Moore

Masters Theses

Chapter 1 Review: This chapter outlines the artist’s statement on his motivation behind the project. This presents a history of engagement with the fantasy medium with the artist and how the fantasy genre has inspired him throughout his childhood and into his adult life. The artist discusses his fascination with the genre and how fantasy provides a safe medium which allows for people to engage in difficult and testing experiences in a setting which they can learn empathy. Chapter 2 Review: This chapter details Joseph Campbell’s Monomythic structure in the form of the Hero’s Journey before engaging with how Christopher …


Prescribing A Change To The Fda's Drug Labeling Rules After The 21st Century Cures Act, P. Sydney Engle Dec 2022

Prescribing A Change To The Fda's Drug Labeling Rules After The 21st Century Cures Act, P. Sydney Engle

Duke Law Journal

Signed into law in 2016, the 21st Century Cures Act offers new hope to patients by empowering the FDA to expedite review of innovative, potentially lifesaving drugs. But these expedited approvals raise the risk that pivotal drug safety and efficacy data will not arise until after the drug is already on the market. The Cures Act failed to respond to two key aspects of shifting the discovery of safety and efficacy data to the postmarket phase. First, the Cures Act did not correspondingly enhance the FDA’s authority to require manufacturers to generate and disclose postmarket information. Second, it did not …


Stabilization Of Mcl-1 By E3 Ligase Traf4 Confers Radioresistance, Ming Li, Feng Gao, Xiaoying Li, Yu Gan, Shuangze Han, Xinfang Yu, Haidan Liu, Wei Li Dec 2022

Stabilization Of Mcl-1 By E3 Ligase Traf4 Confers Radioresistance, Ming Li, Feng Gao, Xiaoying Li, Yu Gan, Shuangze Han, Xinfang Yu, Haidan Liu, Wei Li

Faculty, Staff and Students Publications

The E3 ligase TNF receptor-associated factor 4 (TRAF4) is frequently overexpressed and closely related to poor prognosis in human malignancies. However, its effect on carcinogenesis and radiosensitivity in oral squamous cell carcinoma (OSCC) remains unclear. The present study found that TRAF4 was significantly upregulated in primary and relapsed OSCC tumor tissues. Depletion of TRAF4 markedly improved the sensitivity of OSCC cells to irradiation (IR) treatment, showing that tumor cell proliferation, colony formation and xenograft tumor growth were reduced. Mechanistically, IR promoted the interaction between TRAF4 and Akt to induce Akt K63-mediated ubiquitination and activation. TRAF4 knockout inhibited the phosphorylation of …


Supervision In Nature: Integrating The Natural World In Supervision, Kimberly L. A. Walker, Jacqueline M. Swank Dec 2022

Supervision In Nature: Integrating The Natural World In Supervision, Kimberly L. A. Walker, Jacqueline M. Swank

Journal of Counselor Preparation and Supervision

Counseling supervision is a crucial component to the development of a counselor. Supervisors may integrate a variety of supervision techniques within the supervision process to facilitate the growth of the supervisee. This manuscript focuses on the integration of nature within the supervision process. We discuss the benefits of nature for humans, present nature-based supervision activities within the eight domains of professional functioning within the Integrated Developmental Model (IDM) of supervisee development, and discuss considerations for integrating nature within the supervision process.


Addressing Anti-Fat Bias: A Crash Course For Counselors And Counselors-In-Training, Stella B. Kerl-Mcclain, Cort M. Dorn-Medeiros, Kelsey Mcmurray Dec 2022

Addressing Anti-Fat Bias: A Crash Course For Counselors And Counselors-In-Training, Stella B. Kerl-Mcclain, Cort M. Dorn-Medeiros, Kelsey Mcmurray

Journal of Counselor Preparation and Supervision

People with larger body sizes are often the target of harmful stereotypes such as being lazy, unattractive, and unintelligent. Such stereotypes are part of an extensive system of oppression often intersecting with racism, classism, and ableism. When counselors and counselors-in-training are unaware of their own biases related to body size, larger bodied clients are at risk for further harm within the very place they are seeking support. This article provides professional counselors and counselors-in-training with the historical knowledge needed to examine their own biases and prejudices around body size and fatness to become better counselors and advocates for all clients. …


Assessing Mothers’ Perception Of Maternal Health Services In Rural Areas Of Yatta, Hebron: A Pilot Study From Palestine, Hussien Jabbarien Jabbarien, Inad Nawajah, Mohannad Jazzar Dec 2022

Assessing Mothers’ Perception Of Maternal Health Services In Rural Areas Of Yatta, Hebron: A Pilot Study From Palestine, Hussien Jabbarien Jabbarien, Inad Nawajah, Mohannad Jazzar

Hebron University Research Journal-A (Natural Sciences) - (مجلة جامعة الخليل للبحوث- أ (العلوم الطبيعيه

Access to high-quality care during pregnancy and childbirth is a challenge for women living in Al-Masafer of Yatta and Bedouin areas, considered C areas under Israeli administrative & security supremacy. Realizing clients' perception and satisfaction with the quality of maternal healthcare services will enable maternal health decision-makers & providers to assess the impact of their services on the clients' demands and perceptions. This study aims to measure women's perception of maternal health services provided in Al- Masafer of Yatta and Bedouin areas. A cross-sectional descriptive quantitative study of 59 women, selected purposefully from Al-Masafer of Yatta and the Bedouin areas, …


The Antioxidant And Antibacterial Activity Of Oriental Strawberry (Arbutus Andrachne L.): A Review Article, Sihem Mekchiche, Khalid Al-Ismail, Hamed Takruri Dec 2022

The Antioxidant And Antibacterial Activity Of Oriental Strawberry (Arbutus Andrachne L.): A Review Article, Sihem Mekchiche, Khalid Al-Ismail, Hamed Takruri

Hebron University Research Journal-A (Natural Sciences) - (مجلة جامعة الخليل للبحوث- أ (العلوم الطبيعيه

Oxidation is one of the most critical processes in food systems. It has an impact on a variety of dietary ingredient interactions, resulting in both desired and unwanted results. It was found in many studies that high concentrations of synthetic antioxidants may havesome carcinogenic effects in some animals, thus natural antioxidants would be analternative to synthetic antioxidants in food. These natural antioxidants can be present in any plant part, including grains, fruits, leaves, nuts, seeds, roots and barks. Many studies showed that there is an inverse relationship between the dietary intake of medicinal plants rich in antioxidants and the prevalence …


Regresando De Narnia: Entre La Encrucijada De Armarios Y Templos, Hugo Córdova Quero, Saúl Serna Segura, Jorge A. Aquino Ph.D., Miguel H. Diaz Dec 2022

Regresando De Narnia: Entre La Encrucijada De Armarios Y Templos, Hugo Córdova Quero, Saúl Serna Segura, Jorge A. Aquino Ph.D., Miguel H. Diaz

Conexión Queer: Revista Latinoamericana y Caribeña de Teologías Queer

This issue of Queer Connection presents the work of authors who have left the infancy of Narnia, covering topics ranging from queer poetics, honest conversations about sexuality in the Roman Catholic Church, and online Eucharists to the deconstruction of Islamic texts for the acceptance of queer people. All of these studies point toward liberation and societal transformation. In Christianity, the TLL has made reflecting on oppression and liberation possible. Still, its novelty lies in reflecting faith elaborated within a practice of liberation done by oppressed people through their movements. In this sense, liberation is transformation and change, a new world …


Reflections Of A «Recovering Outer Catholic», Jorge A. Aquino Ph.D. Dec 2022

Reflections Of A «Recovering Outer Catholic», Jorge A. Aquino Ph.D.

Conexión Queer: Revista Latinoamericana y Caribeña de Teologías Queer

This essay comments on the long-deferred need for Latinx Catholic theologians to resist Roman Catholic teaching on sexuality by taking it out of the margins and integrating it as a co-equal topic of theological reflection. Based on the author’s 2014 presidential address to the Academy of Catholic Hispanic Theologians of the United States (ACHTUS), it reviews the challenges — pastoral, theological, social, and psychological — of confronting homophobia and the exclusion of queer subjects by the Roman Catholic Church.


Textos Islámicos: Una Fuente Para La Aceptación De Las Personas Queer En La Sociedad Musulmana Mayoritaria, Muhsin Hendricks Dec 2022

Textos Islámicos: Una Fuente Para La Aceptación De Las Personas Queer En La Sociedad Musulmana Mayoritaria, Muhsin Hendricks

Conexión Queer: Revista Latinoamericana y Caribeña de Teologías Queer

This article seeks to reveal that Islam, at its core, does not condemn non- heterosexual sexual intimacy. On the contrary, it accepts it as part of a divine plan. In its true sense of peace and justice, Islam accepts a person’s sexual orientation as an intrinsic part of their biological and psychological makeup. He shows that the prohibition of same-sex marriages in Islam does not come from the Koran but from the legal construction of marriage and that sexual relations are both gendered and hierarchical. However, his study does not focus on Qur’anic texts that can be interpreted in support …


Accommodating Victims With Mental Disabilities, Danielle Shelton Dec 2022

Accommodating Victims With Mental Disabilities, Danielle Shelton

Dickinson Law Review (2017-Present)

The #MeToo movement has brought the voices of victims of sexual assault into the public’s eye and, in turn, into the legal system. As its name suggests, the movement’s strength lies in numbers—it is, after all, hard to ignore the collective voices of a group of considerable size and visibility. This Article argues that another group of victims—namely, victims who have mental disabilities— also are desperately in need of their own movement to raise public awareness and bring about reform. However, because of their cognitive and communication impairments, this group of victims is unlikely to effectuate reform itself. Instead, these …


Navigating Beyond The Lodestar: Borrowing The Federal Sentencing Guidelines To Provide Fee-Shifting Predictability, Matthew Ahn Dec 2022

Navigating Beyond The Lodestar: Borrowing The Federal Sentencing Guidelines To Provide Fee-Shifting Predictability, Matthew Ahn

Dickinson Law Review (2017-Present)

The lodestar has been the dominant calculation method for fee-shifting awards for nearly 40 years. But the lodestar has numerous persistent issues: it leads to extra litigation and judicial effort, it results in highly variable fee awards, and it incentivizes plaintiffs’ attorneys to bill extravagantly and reject settlement. This Article argues that these issues with the lodestar, along with many others, result from a mismatch between the lodestar and the purpose of the underlying fee-shifting statutes, which is to encourage attorneys to bring suits that would not normally be economically viable. Encouraging attorneys to do so requires the fee awards …


How Not To Be A Federal Criminal: A Review Of Mike Chase’S How To Become A Federal Criminal And The Case For Inclusion Of His Illustrated Handbook In American Law Schools, Zachary Stendig Dec 2022

How Not To Be A Federal Criminal: A Review Of Mike Chase’S How To Become A Federal Criminal And The Case For Inclusion Of His Illustrated Handbook In American Law Schools, Zachary Stendig

Dickinson Law Review (2017-Present)

No abstract provided.


Ccl4 Regulates Eosinophil Activation In Eosiccl4 Regulates Eosinophil Activation In Eosinophilic Airway Inflammationnophilic Airway Inflammation, Hanh Hong Chu, Yoshiki Kobayashi, Dan Van Bui, Yasutaka Yun, Linh Manh Nguyen, Akitoshi Mitani, Kensuke Suzuki, Mikiya Asako, Akira Kanda, Hiroshi Iwai Dec 2022

Ccl4 Regulates Eosinophil Activation In Eosiccl4 Regulates Eosinophil Activation In Eosinophilic Airway Inflammationnophilic Airway Inflammation, Hanh Hong Chu, Yoshiki Kobayashi, Dan Van Bui, Yasutaka Yun, Linh Manh Nguyen, Akitoshi Mitani, Kensuke Suzuki, Mikiya Asako, Akira Kanda, Hiroshi Iwai

Faculty, Staff and Student Publications

Eosinophilic chronic rhinosinusitis (ECRS) is a refractory airway disease accompanied by eosinophilic inflammation, the mechanisms of which are unknown. We recently found that CCL4/MIP-1β-a specific ligand for CCR5 receptors-was implicated in eosinophil recruitment into the inflammatory site and was substantially released from activated eosinophils. Moreover, it was found in nasal polyps from patients with ECRS, primarily in epithelial cells. In the present study, the role of epithelial cell-derived CCL4 in eosinophil activation was investigated. First, CCL4 expression in nasal polyps from patients with ECRS as well as its role of CCL4 in eosinophilic airway inflammation were investigated in an in …


Nuclear S6k1 Enhances Oncogenic Wnt Signaling By Inducing Wnt/Β-Catenin Transcriptional Complex Formation, Min Gyu Lee, Hwamok Oh, Jong Woo Park, Jueng Soo You, Jeung-Whan Han Dec 2022

Nuclear S6k1 Enhances Oncogenic Wnt Signaling By Inducing Wnt/Β-Catenin Transcriptional Complex Formation, Min Gyu Lee, Hwamok Oh, Jong Woo Park, Jueng Soo You, Jeung-Whan Han

Faculty, Staff and Student Publications

Ribosomal protein S6 kinase 1 (S6K1), a key downstream effector of the mammalian target of rapamycin (mTOR), regulates diverse functions, such as cell proliferation, cell growth, and protein synthesis. Because S6K1 was previously known to be localized in the cytoplasm, its function has been mainly studied in the cytoplasm. However, the nuclear localization and function of S6K1 have recently been elucidated and other nuclear functions are expected to exist but remain elusive. Here, we show a novel nuclear role of S6K1 in regulating the expression of the Wnt target genes. Upon activation of the Wnt signaling, S6K1 translocated from the …


Tourists’ Selfies Storytelling: Preferences, Intentions, And Concerns For Practise In The Tourism And Hospitality Industry, Abdallah Elshaer, Rong Huang, Asmaa Marzouk Dec 2022

Tourists’ Selfies Storytelling: Preferences, Intentions, And Concerns For Practise In The Tourism And Hospitality Industry, Abdallah Elshaer, Rong Huang, Asmaa Marzouk

Plymouth Business School

Photography has recently received significant academic interest as a popular tourist activity. However, tourist selfie practises have not yet been thoroughly examined by tourism scholars. This study aimed to investigate tourist selfies storytelling and to determine if tourists'selfies at tourist destinations reveal specific aspects of the host destination, implying an embodiment of particular preferences, intentions, and motivations. In this study, an exploratory analysis employing a two-step qualitative approach was conducted. A semiotic analysis of 317 tourist selfie photos and two phases of in-depth interviews with eleven tourists visiting Egypt on a 7-day packaged tour were used. The findings reveal that …


Feminine Body Between Appropriation And Tyranny In Sulaiman Al- Shatti’S Novel "Silence Extends", “Semiotic Reading”, Khitam Othman Al-Khouli Dec 2022

Feminine Body Between Appropriation And Tyranny In Sulaiman Al- Shatti’S Novel "Silence Extends", “Semiotic Reading”, Khitam Othman Al-Khouli

Association of Arab Universities Journal for Arts مجلة اتحاد الجامعات العربية للآداب

This paper addresses the phenomena of appropriation and tyranny in the face of the feminine body in the novel "Extending Silence" by the Kuwaiti novelist Sulaiman al- Shatti. It depends on the analytical method that includes the following elements: the connotation of the title, the authoritarian woman, the oppressed woman, and the semiotics of the body. It discusses the key phenomena that surface the novel. As regards the connotation of the title, it is an efficacious element that shows up the theme of silence that extends throughout the novel and becomes a dominant element in the space of the narrative …


Picturizing Animals In The Arabic, Persian And Turkish - Azerbaijani Proverbs: A Comparative Study, Kubra Jabbarli Dec 2022

Picturizing Animals In The Arabic, Persian And Turkish - Azerbaijani Proverbs: A Comparative Study, Kubra Jabbarli

Association of Arab Universities Journal for Arts مجلة اتحاد الجامعات العربية للآداب

Animals have a special place in human thought and life throughout history since they were used as a symbol to refer to different purposes in stories and proverbs. So, they play an important role in the people's culture and literature. Thus, animal behaviors and characteristics were not the same for all nations due to the geographic nature of each nation, the impact of animals' in it, and to the beliefs, customs and traditions of each nation.From this standpoint, we found that there were many common beliefs among nations regarding animals and their behaviors. At the same time, we found that …


The Connotations And Cultural Dimensions In The Introduction Of Ibn Bassam Al-Shantrini’S Al-Thakhira, Mohammed Faisal Dec 2022

The Connotations And Cultural Dimensions In The Introduction Of Ibn Bassam Al-Shantrini’S Al-Thakhira, Mohammed Faisal

Association of Arab Universities Journal for Arts مجلة اتحاد الجامعات العربية للآداب

Andalusia witnessed progress in the sciences, arts, urbanism, literature, economic and political aspects. This progress prompted many scholars and writers to mention the merits of this culture, and celebrate it for successive generations through their poems and blogs so this becomes a witness on the work of the fathers and grandfathers and this brings pride of those ancient virtues. The book Al-Thakhira was a good example on embodying the meanings and dimensions of Andalusian culture and civilization through what the book has from the translations of the great people in Andalusia. If one just looks at the introduction of this …


Do Emotional Support Animals Actually Help?, Harold Herzog Dec 2022

Do Emotional Support Animals Actually Help?, Harold Herzog

Herzog - Companion Animal Issues

U.S. federal law allows people with mental-health disorders to have emotional support animals in college dorms and no-pet apartments. This legislation assumes there are proven benefits of of living with emotional support animals. There is no substantial research that supports the use of emotional support animals in public housing or for air travel.


Dissecting Interactions Across Gene Regulatory Layers In C. Elegans, Morgan Taylor Dec 2022

Dissecting Interactions Across Gene Regulatory Layers In C. Elegans, Morgan Taylor

Biological Sciences Theses and Dissertations

The nematode Caenorhabditis elegans is a powerful tool for studying nervous system genetics. Though relatively simple compared to mammals, C. elegans boasts a remarkably well-conserved neuronal genome and proteome, and its utility in the characterization of neuronal genes has been well-established. However, gene expression is often controlled by complex interactions between multiple genes, and teasing apart the functions of individual genes within such networks remains a challenge. Dissecting these interaction networks is crucial in determining the multifaceted functions of important, conserved regulatory genes. Here we explore interactions between gene regulatory layers in the C. elegans nervous system, employing a synthetic …


Development Of A Muc1 Cancer Immunotherapy Using Complement Targeted Liposomes And Organoplatinum (Iv) Complex As An Effective Anticancer Drug, Ameneh Arabi Dec 2022

Development Of A Muc1 Cancer Immunotherapy Using Complement Targeted Liposomes And Organoplatinum (Iv) Complex As An Effective Anticancer Drug, Ameneh Arabi

Chemistry and Biochemistry

The development of therapeutic and preventive cancer vaccines has been on the rise in the past decade. Extensive tumor antigen libraries supply researchers with a wide variety of targets for developing cancer vaccines. Cancer vaccines aim to induce tumor regression, eradicate tumors and establish lasting antitumor memory, while avoiding adverse reactions. However, achieving this goal is hampered by the challenges of finding tumor antigens to incite an effective immune response and creating an efficient delivery system to deliver the antigen to target cells. In this thesis, we discuss how to integrate Toll Like Receptor (TLR) agonists with a MUC1 cancer …