Digital Commons Network^™

Reclaiming Establishment: Identity And The 'Religious Equality Problem', Faraz Sanei

Scholarly Articles in Law Reviews & Journals

Since at least 2017, the Court has implicitly recognized a right of equal access to generally available public benefits based on the beneficiary’s religious identity or status. In Carson v. Makin (2022), the Court went a step further and, for the first time, concluded that the “statususe distinction lacks a meaningful application” in both theory and practice. It then held that restrictions on the use of public benefits for sacral purposes amount to religious discrimination because they impose substantial burdens on free exercise rights. Carson’s holding, and the rationale underlying it, contravene settled case law and effectively gut the Establishment …

Mcconnell Hall, Central Washington University

What is in a Name?

No abstract provided.

Standardizing State Vote-By-Mail Deadlines In Federal Elections, Jason Nagel

Cardozo Law Review de•novo

The litigation over the vote-by-mail process during the 2020 general election revealed that absentee ballot voting disputes should not be left entirely to the courts. Rather, this Note argues that Congress should utilize its constitutional Elections Clause power to standardize federal vote-by-mail processes, and proposes specific elements that Congress should include in such legislation.

Staying In The Takings Lane: The Compensation Issue In Cedar Point Nursery, Mark Kelman

Cardozo Law Review de•novo

The Supreme Court held in Cedar Point Nursery v. Hassid that a California regulation mandating that union organizers have occasional access to privately owned farms was a per se taking because it stripped the farm owners of the right to exclude. The decision almost certainly departed from prior law, and I briefly review some of the critiques of the majority opinion. But my focus is on questions that arise if one accepts the Court’s conclusion that the regulation is indeed a taking: First, I briefly discuss whether we should permit the taking so long as the owners are compensated or …

The Criminal Legal System Doesn’T Care About Your Mental Illness, Fredrick E. Vars

Cardozo Law Review de•novo

Why would a beloved small-town doctor with no history of violence suddenly strangle his father to death? The Other Dr. Gilmer is a gripping account of the search for an answer to this question. It turns out the doctor has a rare neurological disorder that likely caused the killing. If only the diagnosis had come before trial, the author believes, the doctor would not have been convicted of first-degree murder and sentenced to life without parole. That belief is appealing, but naïve. Jails and prisons are full of people with mental illness. Misdiagnosis is not the reason. A close examination …

Innate Property: The Danger Of Incongruency Between Law And The Biological And Behavioral Roots Of Property And Possessiveness, Aaron Schwabach

Cardozo Law Review de•novo

Property law is, in some areas, dangerously out of step with property expectations. Property—the idea that a place, object, or idea can belong to a person—is at the root of the world’s economies and thus also at the root of much of its laws. Property is neither solely a creature of positive law, nor of some abstract natural law with a moral underpinning, but rather may be biologically determined, much as Noam Chomsky proposed for languages in Aspects of the Theory of Syntax.1 The idea that ownership is at least behaviorally, and perhaps to some extent instinctively, determined has been …

Prism-19, Center For Complex Operations

PRISM (Full PDF Issues)

This special issue of PRISM is about the different perceptions and reactions to COVID-19 as people and governments experienced the disease, and their diverse understanding of its implications for national and international security.

Genetically Engineered Food, Food Security, And Climate Change, Joanna K. Sax

Faculty Scholarship

Malnutrition is the leading cause of death and disease worldwide. Climate change is an existential crisis. We need to feed people and address the role of agriculture in climate change – at the same time. This is problematic, as agriculture inherently creates issues that contributes to climate change. Utilizing science, through genetically engineered crops, is one way to close the harm gap between food security and climate change. This essay addresses the controversial issue of genetically engineered crops with the complicated issues of food security and climate change by analyzing three main issues: (1) how the science of genetically engineered …

Transcranial Magnetic Stimulation For Post-Traumatic Stress Disorder, Amber N. Edinoff, Tanner L. Hegefeld, Murray Petersen, James C. Patterson, Christopher Yossi, Jacob Slizewski, Ashley Osumi, Elyse M. Cornett, Adam M. Kaye, Jessica S. Kaye, Vijayakumar Javalkar, Omar Viswanath, Ivan Urits, Alan David Kaye

School of Pharmacy Faculty Articles

Post-traumatic stress disorder (PTSD) is a psychiatric disorder that causes significant functional impairment and is related to altered stress response and reinforced learned fear behavior. PTSD has been found to impact three functional networks in the brain: default mode, executive control, and salience. The executive control network includes the dorsolateral prefrontal cortex (DLPFC) and lateral PPC. The salience network involves the anterior cingulate cortex, anterior insula, and amygdala. This latter network has been found to have increased functional connectivity in PTSD. Transcranial Magnetic Stimulation (TMS) is a technique used in treating PTSD and involves stimulating specific portions of the brain …

Combination Olanzapine And Samidorphan For The Management Of Schizophrenia And Bipolar 1 Disorder In Adults: A Narrative Review, Hannah W. Haddad, Elena Boardman, Brooke Williams, Rama Mouhaffel, Adam M. Kaye, Alan David Kaye

School of Pharmacy Faculty Articles

Schizophrenia is a debilitating psychotic disorder characterized by positive symptoms such as delusions, hallucinations, and disorganized thoughts, and negative symptoms like lack of effect or motivation. Bipolar 1 disorder (B1D) is a psychiatric illness characterized by recurrent manic episodes in alternation with depressive episodes and interspersed periods of euthymia, ultimately resulting in psychological distress and impairment of daily functioning. Effective treatments are needed for both schizophrenia and B1D to reach the treatment goals of reducing the debilitating symptomology, improving social functioning and quality of life, and increasing the chances of recovery and more favorable long-term outcomes. To date, olanzapine is …

Pitolisant, A Novel Histamine-3 Receptor Competitive Antagonist, And Inverse Agonist, In The Treatment Of Excessive Daytime Sleepiness In Adult Patients With Narcolepsy, Noeen Sarfraz, David Okuampa, Hannah Hansen, Mark R. Alvarez, Elyse M. Cornett, Juyeon Kakazu, Adam M. Kaye, Alan David Kaye

School of Pharmacy Faculty Articles

Narcolepsy is a debilitating sleep disorder that presents with excessive daytime sleepiness (EDS) and cataplexy, which is a sudden paralysis of muscle tone triggered by strong emotions such as laughing. It is also associated with many other disorders, including psychiatric disorders, neurologic illnesses, and medication side effects. Common causes of delayed and incorrect diagnoses of these conditions include lack of physician familiarity with narcolepsy symptoms and comorbidities which mask narcolepsy signs and symptoms. Current pharmacologic therapies include Modafinil and Armodafinil for EDS and sodium oxybate for cataplexy. This review discusses the epidemiology, pathophysiology, risk factors, presentation, treatment of narcolepsy, and …

Aduhelm, A Novel Anti-Amyloid Monoclonal Antibody, For The Treatment Of Alzheimer's Disease: A Comprehensive Review., Hannah W. Haddad, Garett W. Malone, Nicholas J. Comardelle, Arielle E. Degueure, Salomon Poliwoda, Rachel J. Kaye, Kevin S. Murnane, Adam M. Kaye, Alan David Kaye

School of Pharmacy Faculty Articles

Alzheimer's disease (AD) is the most common form of dementia affecting millions of individuals, including family members who often take on the role of caregivers. This debilitating disease reportedly consumes 8% of the total United States healthcare expenditure, with medical and nursing outlays accounting for an estimated $290 billion. Cholinesterase inhibitors and N-methyl-D-aspartate receptor antagonists have historically been the most widely used pharmacologic therapies for patients with AD; however, these drugs are not curative. The present investigation describes the epidemiology, pathophysiology, risk factors, presentation, and current treatment of AD followed by the role of the novel monoclonal antibody, Adulhelm, in …

Rimegepant For The Treatment Of Migraine., Amnon A. Berger, Ariel Winnick, Austin H. Carroll, Alexandra Welschmeyer, Nathan Li, Marc Colon, Antonella Paladini, Giovanni F. Ramírez, Jamal Hasoon, Elyse M. Cornett, Jaehong Song, Giustino Varrassi, Adam M. Kaye, Alan David Kaye, Latha Ganti

School of Pharmacy Faculty Articles

Migraine is a common form of primary headache, affecting up to 1 in every 6 Americans. The pathophysiology is an intricate interplay of genetic factors and environmental influence and is still being elucidated in ongoing studies. The trigeminovascular system is now known to have a significant role in the initiation of migraines, including the release of pain mediators such as CGRP and substance P. Traditional treatment of migraine is usually divided into acute and preventive treatment. Acute therapy includes non-specific therapy, such as NSAIDs and other analgesics, which may provide relief in mild to moderate migraines. 5-HT1 agonists may provide …

Why The Recognition Of Sentience Is So Important For Animal Welfare, Mark Jones

Animal Sentience

Rowan et al. (2022) provide a useful summary of the history and development of the philosophical, public, and legal recognition of animal sentience and its importance in improving the welfare of animals. Here I argue for the incorporation of the precautionary principle in sentience recognition, and the wider significance of sentience recognition to the current climate, biodiversity and human health crises.

Selected Dietary Plant-Based Proteins For Growth And Health Response Of Nile Tilapia Oreochromis Niloticus, Tzodoq O. Magbanua, Janice A. Ragaza

Biology Faculty Publications

Tilapia culture is one of the largest sectors of global aquaculture. Among the different species of tilapia, Nile tilapia (Oreochromis niloticus) is perhaps the top cultured species. The production of Nile tilapia has been continually increasing throughout the years resulting in genetic deterioration. Several tilapia strains with better growth performance and adaptive capability to survive in different culture conditions have been developed to alleviate the crisis. Increased demand for Nile tilapia implies higher farming cost. Plant-based proteins are utilized as partial or complete fishmeal replacements to reduce feed cost. However, these proteins can adversely affect and alter growth …

Investigating The Relationship Between The Microbiome And Neuroactive Metabolites In Huntington Disease Model Mice, Christian Millot

Electronic Theses and Dissertations, 2020-2023

Huntington Disease (HD) is an autosomal dominant neurodegenerative disorder caused by a trinucleotide repeat expansion mutation in the huntingtin (HTT) gene. HD is characterized by neurological symptoms, including motor, cognitive, and psychiatric decline. A non-neurological symptom, metabolic dysfunction, is also common in HD and can cause weight change, a feature recapitulated in HD mice. There is a need for a better understanding of the weight changes associated with HD, because patients with a higher body mass index show slower disease progression. Our lab has shown that metabolic dysfunction in HD mice is the result of a disrupted circadian feeding rhythm …

Investigation Of Realism In Facial Characteristics And Anthropomorphic Language In The Design Of Multimedia Instruction, Ecem Olcum

Electronic Theses and Dissertations, 2020-2023

Emotional design elements have recently been added to the research in cognitive load and multimedia learning (Um et al., 2012). One aspect of eliciting positive emotions is to use anthropomorphic design, which has been found to increase learning performance (Um et al., 2012; Plass et al., 2014; Park et al., 2015; Schneider et al., 2018). The current research aimed to investigate three design factors in three studies: anthropomorphism in verbal and visual design, single-frame or multi-frame illustrations, and realism of the anthropomorphic visual design. The first study confirmed that the anthropomorphic verbal and visual materials were perceived as anthropomorphic by …

Role Of Biological Clocks In Ant Behavioral Plasticity And Parasitic Manipulation Of Ant Behavior, Biplabendu Das

Electronic Theses and Dissertations, 2020-2023

Living organisms exhibit daily rhythms as a way to anticipate predictable fluctuations in their environment. Such daily rhythmicity is the phenotypic outcome of oscillating genes and proteins, driven by an endogenous biological clock. Clock-controlled behavioral rhythms are inherently "flexible" since their phase, amplitude, and period can change throughout an animal's life hallmarked by changes in so-called chronotype. How this inherent plasticity of clock-controlled rhythms is linked to plasticity of behavior is still an open question in biology. Characterizing the various mechanistic links between plasticity of the animal clock and behavioral state will not only shed light on the molecular underpinnings …

Killing Two Birds With One Stone: An Examination Of The Role Of Three-Dimensional Energy In The Relationship Between Health Behaviors And Job Performance., Nina Steigerwald

Electronic Theses and Dissertations, 2020-2023

The positive effects of health behaviors on job performance have been reported. Specifically, there is evidence to suggest that getting adequate quantity and quality sleep, staying physically active, and following a nutritious diet, are linked to enhanced functioning and work-related outcomes. Although some studies have examined the role of energy in relation to health behaviors and performance, research looking at energy as an underlying mechanism in the health behaviors – performance link is both scarce and fragmented. The present study examines the role of energy as a potential mediator, devoting particular attention to its emotional, mental, and physical component. Using …

Non-Invasive Detection Of Elevated Intracranial Pressure Using Spontaneous Tympanic Membrane Pulsation, Rajkumar Dhar

Electronic Theses and Dissertations, 2020-2023

Monitoring intracranial pressure (ICP) is a standard diagnostic tool for various neurological conditions such as head injury, ruptured aneurysms, intracerebral and intracranial hemorrhage, and hydrocephalus. Currently, ICP monitoring relies on invasive pressure measurements. These include intraventricular catheter, subdural screw, epidural sensor, and lumbar puncture. Invasive methods pose the risk of infection and hemorrhage, are expensive, and require special clinical skills. A noninvasive method that is reliable, simple to use, low-cost, and provides easily interpretable results can help avoid the complications associated with the invasive methods. This study proposes a novel method for noninvasive ICP monitoring using tympanic membrane pulsation (TMp). …

Not All Influence Is Born Equal: On The Effects Of Various Types Of Behavioral Influence Relationships On Social Media, Chathurani Senevirathna

Electronic Theses and Dissertations, 2020-2023

Typically, online social influence is analyzed using a single metric approach. However, social influence is not monolithic; different users exercise different influences in different ways, and influence is correlated with the user and content-specific attributes. One such attribute could be whether the action is an initiation of a new post, a contribution to a post, or a sharing of an existing post. Thus, this dissertation uses this platform-independent action classification and models the influence as multiple entities and examines social networks through the perspective of behavioral influence propagation. Two empirical studies are present in this dissertation. The first study presents …

Teaching Sustainability: Does Style Matter?, Fethiye Ozis, Shannon Lynn Isovitsch Parks, Deborah Sills, Mustafa Akca, Christine Kirby

Faculty Journal Articles

Purpose – This paper aims to analyze how a tangram activity improved students’ abilities to explain sustainability, articulate a positive perception of sustainable design and relate sustainability with innovation in engineering design. Design/methodology/approach – The concept of paradigm shift was introduced in the classroom by using a tangram activity to help students understand that sustainable design requires out-of-the-box thinking. Instructors from three institutions teaching various levels of sustainability courses to engineering majors used the activity to introduce sustainable design, then measured the understanding and appreciation of the concepts introduced through the tangram activity with pre- and post-activity surveys. Findings – …

Bio 2005g : Human Biology, Biological Sciences

Approved Course Proposals

No abstract provided.

Elucidating The Role Of Polycomb Repressive Complex 2 In Lung Stem Cell Fate And Lung Disease, Aria Byrd

Theses and Dissertations--Toxicology and Cancer Biology

The average human lungs take ~22,000 breaths and inhale ~2,000 gallons of air each day. This organ is the primary conduit for the transfer of oxygen to the internal organs, making it crucial for the sustainment of life. Consequently, mechanical malfunction of the lungs and/or pollution of inhaled air negatively impact internal organ function and ultimately put survival in jeopardy. Epigenetics, by nature, is a plastic phenomenon in which environmental stimuli influence short term, long term, and generational gene expression patterns. Chronic exposure of harmful stimuli to the lung epithelium has also been shown to alter epigenetic pathways, engender aberrant …

Extracellular Vesicles And Cancer Therapy: An Insight Into The Role Of Oxidative Stress, Jenni Ho

Theses and Dissertations--Toxicology and Cancer Biology

As a result of improvements in cancer detection and treatment methods, a growing population of cancer survivors are living with side effects associated with their cancer therapy. Oxidative stress plays a significant role in the development of cancer and as a mechanism for cancer therapy to exert its therapeutic effects, resulting in off-target tissue damage. Radiation has been long established as a means to utilize the generation of reactive oxygen species to kill cancer cells, and 50% of chemotherapy agents currently used are associated with inducing oxidative stress. One major side effect observed in cancer survivors is a decline in …

Constitutional Law—Answering Justice Barrett’S Fulton Prompt: The Case For A Narrow Reconsideration Of Free Exercise, Andrew Lavender

Western New England Law Review

In Fulton v. City of Philadelphia, the Supreme Court, for the second time in three years, considered a case involving the conflict between First Amendment religious, speech, and associational freedoms and the civil rights of the LGBTQ community. And, for the second time, the Court arrived at an apparent compromise, issuing a narrow, factual ruling in favor of the party seeking an exception from antidiscrimination law while avoiding any firm precedent that might create a broader exception.

In addition to this substantive dodge, the Court also “sidestep[ped] the question on which certiorari had been granted: whether to overrule Employment …

Tissue And Sex-Specific Rna Editing During Induced Acute Inflammation, Claire E. Nichols

Graduate Theses/Dissertations

A-to-I RNA editing is a process where select adenosine (A) nucleotides are deaminated by an editing enzyme, ADAR, to become inosines (I) in RNA transcripts. RNA editing can affect the sequence of the encoded protein and the regulation of the RNA. ADAR1 also plays a role in regulating innate immunity and its expression is upregulated during inflammation. Current data on the effects of increasing ADAR1 on RNA editing is limited, and most studies are completed only in male animals. We are interested in expanding RNA editing data to include female animals. Lipopolysaccharide (LPS) was used to induce acute inflammation and …

Cultural Heritage And Storytelling: The Role Of Mythology And Folklore In Popular Fictional Novels, Katrina Powers

A with Honors Projects

An ethnographic paper focusing on how mythology and folklore in popular fictional novels connects readers to cultural heritage.

A Job-Demand Resource Theory And Psychological Flexibility Integrated Model Of Police Officer Burnout, Lucas David Baker

Dissertations and Theses

Police officers encounter stressors as a result of job responsibilities that contribute to high rates of occupational burnout. Defined by three primary components (emotional exhaustion, depersonalization, and professional inefficacy), burnout is associated with health- and work-related problems among officers. In addition, police agencies incur significant costs associated with burnout due to performance decline and turnover. Officer burnout is also a matter of public interest given that burnout is associated with low prosocial behavior and high use of force. As such, research that aims to explore the formation and maintenance of officer burnout may be consequential for the profession and society …

True Pauline Worship Is Trinitarian: A Look At Paul’S Trinitarian Presuppositions, Connie Heberlein

Masters Theses

This thesis seeks to show that true Pauline worship is Trinitarian. Thus, proper Christian worship must be Trinitarian. This work begins by examining the Shema and exploring the unique identity of God presented in the Old Testament and the literature of Second Temple Judaism. Building on this foundation, this work evaluates statements found in Paul’s letters in which Paul reformulates the Shema to include Christ and the Spirit in the divine identity of God. The goal is to understand how the first Christians, who were Jews committed to the exclusive worship of Yahweh, moved from monotheistic worship to Trinitarian worship …