Digital Commons Network^™

Predictive Significance Of Interleukins 17a And 33 In Risk Of Relapsing–Remitting Multiple Sclerosis, Milad Abdul Salam Al-Naseri, Ali Hussein Ad’Hiah, Ehab Dawood Salman

Baghdad Science Journal

Cytokines are signaling molecules between inflammatory cells that play a significant role in the pathogenesis of a disease. Among these cytokines are interleukins (ILs) 17A and 33, and accordingly, the current case-control study sought to investigate the role of each of the two cytokines in the risk of developing multiple sclerosis (MS). Sixty-eight relapsing-remitting MS (RRMS) Iraqi patients and twenty healthy individuals (control group) were enrolled. Enzyme linked immunosorbent assay (ELISA) kits were used to determine serum levels of IL-17A and IL-33. Results revealed that IL-17A and IL-33 levels were significantly higher in MS patients than in controls (14.1 ± …

Assessment Of Groundwater Drinking Sources In Eku And Its Environs, In The Niger-Delta Region Of Nigeria, Ki Iloba, No Akawo, Km Adamu, Or Ohwojeheri, Ma Edafiogho

Baghdad Science Journal

This study assessed the quality of hand-dug drinking water sources in Eku and its environs at Eku I, Samagidi, Eku 2, and Okuechi, using the weighted arithmetic water quality index method. Water samples collected from hand-dug wells at these locations returned values for analyzed parameters. Temperature 26 – 30(⁰C), dissolved Oxygen (D.O) 5.2-8mg/l, biological oxygen demand (BOD) 5.2-8(mg/l), Electrical Conductivity (EC) 77-119(µS/cm), Total suspended solids were (TSS) 20000-120000(mg/l), pH 5.31-7.09, Phosphates 2-9.2(mg/l), Alkalinity 28-160(mg/l), Turbidity, 0.02 -0.19(NTU) Total coliform 2 -48 (cfu/ml) and fungal count 1-502. Variations in the values of these parameters were only significant for phosphate, alkalinity, and …

Association Of Potent Inflammatory Cytokine And Oxidative Dna Damage Biomarkers In Stomach Cancer Patients, Akam Jasim Mustafa, Parween Abdulsamad Ismail

Baghdad Science Journal

The infection with H. Pylori stimulates a signaling cascade that causes the generation of Cytokines and provokes Oxidative stress that is involved in the chronic inflammatory response leads to Gastric cancers. Reactive oxygen species (ROS) produce 8-Hydroxydeoxyguanosine (8-OHdG), the persistent oxidative DNA damage product. The study objective was to assess if there was a link between inflammatory cytokine levels and the presence of Oxidative DNA damage in Gastric tumor patients. In addition, evaluation of the diagnostic and prognostic value of Oxidative DNA damage and inflammatory cytokine biomarkers for Stomach cancers is being conducted. The study was accomplished on medically diagnosed …

Library Newsletter : Issue 4 - 2022, Office Of The University Librarian

Office of the University Librarian Reports

- Message by Peter Gatiti Associate Vice Provost & University Librarian

- Oral History Project (University Archives)

- Book Reviews

- FAS Library

- AKU Author’s Day

- Other Highlights

- CopyrightX

- Digital Repository

- Congratulations

- Library Publications

The Influence Of Electrical Stimulation Pulse Frequency Of Macro-Sieve Electrode On Rat Sciatic Nerve Detection Threshold, Jingyuan Zhang

McKelvey School of Engineering Graduate Student Theses & Dissertations

No abstract provided.

Construction And Use Of Cognitive Maps In Model-Based Control, Ata Karagoz

Arts & Sciences Graduate Student Theses and Dissertations

When making decisions, we sometimes rely on habit and at other times plan towards goals. Planning requires the construction and use of an internal representation of the environment, a cognitive map. How are these maps constructed, and how do they guide goal-directed decisions? We coupled a sequential decision-making task with a behavioral representational similarity analysis approach to examine how relationships between choice options change when people build a cognitive map of the task structure. We found that participants who encoded stronger higher-order relationships among choice options showed increased planning and better performance. These higher-order relationships were more strongly encoded among …

Dei Without Equity: Lab Coat Culture And Persistent Racism In Bioengineering Laboratories, Janet Canady

Arts & Sciences Graduate Student Theses and Dissertations

From biased algorithms to discriminatory devices to medical racism, it is clear that biomedical products are created in ways that reproduce racial disparities in access and use. Yet the most common solutions recommended by biomedical research institutions emphasize diversity, equity, and inclusion practices that research has already proven ineffective and sometimes harmful. In fact, labs rarely scrutinize whether and how their research products reflect racial bias, assumptions, or ideals. In this paper, I shift the focus to consider how bioengineering laboratories function as a site in which racial processes contribute to product outcomes. I ask, what are the racial dynamics …

The Relationship Between Hallucinations And Visuospatial Impairment Among Individuals With Dementia, Ruta Sohoni

Theses and Dissertations

Objective: This study examines the neuropsychological functioning, specifically using the Hooper Visual Organization Test (VOT), to understand the impact of hallucinations on the level of impairment in the visuospatial domain.

Method: Archival data obtained over three years from a total of 73 patients from the Health First Memory Disorder Clinic was used in this study. Participants were included in the study if they endorsed experiencing hallucinations, were given the VOT during their brief neuropsychological evaluation, and were diagnosed with dementia or unspecified neurocognitive disorder. The patient’s electronic medical record was used to retrospectively gather additional details regarding their hallucinations and …

Democracy And Schooling: The Paradox Of Co‐Operative Schools In A Neoliberal Age?, Tom Woodin, Cath Gristy

Plymouth Institute of Education

From the first co-operative trust school at Reddish Vale in Manchester in 2006, the following decade would witness a remarkable growth of ‘co-operative schools’ in England, which at one point numbered over 850. This paper outlines the key development of democratic education by the co-operative schools network. It explains the approach to democracy and explores the way values were put into practice. At the heart of co-operativism lay a tension between engaging with technical everyday reforms and utopian transformative visions of an educational future. A new arena of debate and practice was established with considerable importance for our understanding of …

Detection And Characterisation Of Microplastics And Microfibres In Fishmeal And Soybean Meal, Christopher Walkinshaw, Trevor J. Tolhurst, Penelope K. Lindeque, Richard Thompson, Matthew Cole

School of Biological and Marine Sciences

Aquaculture is an increasingly important source of nutrition for global food security, which is reliant on animal- and plant-based feeds. Anthropogenic particles, including microplastics and semi-synthetic cellulosic fibres, are prolific marine pollutants that are readily consumed by marine organisms, including small pelagic fish commonly used in fishmeal. Conversely, there is no indication plants can accumulate anthropogenic microparticles. We explore whether aquaculture feed presents a route of contamination for farmed fish. Commercially-sourced aquaculture feedstocks, including fishmeals and soybean meal, were processed (KOH digestion and ZnCl2 density separation) and anthropogenic particles characterised using microscopy and spectroscopic methods. Both fishmeal and soybean meals …

Disruption Of Marine Habitats By Artificial Light At Night From Global Coastal Megacities, T. W. Davies, T. J. Smyth, A. E. Wright, A. Edwards-Jones, A Queiros, O. Rendon, S. Tidau, D. Mckee

School of Biological and Marine Sciences

Half of globally significant megacities are situated near the coast, exposing urban marine ecosystems to multiple stressors such as waste-water discharge containing a host of organic and inorganic pollutants, air and noise pollution. In addition to these well recognized sources, artificial light at night (ALAN) pollution is inseparable from cities but poorly quantified in marine ecosystems to date. We have developed a time- and wavelength-resolving hydrological optical model that includes solar (daylight and twilight components), lunar and ALAN source terms and propagates these spectrally through a tidally varying water column using Beer’s Law. Our model shows that for 8 globally …

Nature Tech: A Nascent Ecosystem, Simon J.D. Schillebeeckx

Research Collection Lee Kong Chian School Of Business

When people talk about climate tech, they tend to mean carbon tech. It’s all carbon tunnel vision: Carbon footprint, carbon equivalent, carbon credit, carbon compensation, carbon emission reductions, carbon offsets, decarbonization and so on. By extension, the entire debate about energy transition, energy transformation, clean power and green energy is similarly a debate that is largely held within the carbon tunnel. Make no mistake about it. These are important topics to address. The energy transition will not only prevent catastrophic climate change but have massive benefits for human health by tackling fossil-fuel induced air pollution at the source.As the above …

Biomechanical And Sensory Feedback Regularize The Behavior Of Different Locomotor Central Pattern Generators, Kaiyu Deng, Hillel J. Chiel, Roger D. Quinn

Faculty Scholarship

This work presents an in-depth numerical investigation into a hypothesized two-layer central pattern generator (CPG) that controls mammalian walking and how different parameter choices might affect the stepping of a simulated neuromechanical model. Particular attention is paid to the functional role of features that have not received a great deal of attention in previous work: the weak cross-excitatory connectivity within the rhythm generator and the synapse strength between the two layers. Sensitivity evaluations of deafferented CPG models and the combined neuromechanical model are performed. Locomotion frequency is increased in two different ways for both models to investigate whether the model’s …

Forest Structure And Composition Alleviate Human Thermal Stress, Loïc Gillerot, Dries Landuyt, Rachel Oh, Winston T. L. Chow, Et Al

Research Collection College of Integrative Studies

Current climate change aggravates human health hazards posed by heat stress. Forests can locally mitigate this by acting as strong thermal buffers, yet potential mediation by forest ecological characteristics remains underexplored. We report over 14 months of hourly microclimate data from 131 forest plots across four European countries and compare these to open-field controls using physiologically equivalent temperature (PET) to reflect human thermal perception. Forests slightly tempered cold extremes, but the strongest buffering occurred under very hot conditions (PET >35°C), where forests reduced strong to extreme heat stress day occurrence by 84.1%. Mature forests cooled the microclimate by 12.1 to …

Vista: December 1, 2022, University Of San Diego

USD Vista (1965-)

No abstract provided.

Engineer And Test A Biodegradable Microneedle Patch To Deliver Meloxicam For Managing Pain In Cattle, Katherine Alejandra Miranda Munoz

Graduate Theses and Dissertations

Microneedle patches are a promising source for transdermal diffusion of macromolecules and are designed to painlessly penetrate the skin. In this study, a biodegradable chitosan microneedle patch to deliver meloxicam for managing pain in cattle was tested. The potential of reuse of the polymeric solution to fabricate the patches, optimization of fabrication, morphological analysis of the microneedle patch and analysis of preservation of the chemical composition after sterilization were evaluated. In-vitro analysis consisted of studying in-vitro penetration mechanical properties, compression testing analysis of microneedle patch, and in-vitro drug release analysis. In-vivo studies were performed to analyze the dissolution capability of …

Scarico: It’S Only A Movie, Most Of The Time, Thomas Nelson

Graduate Theses and Dissertations

Exploitation cinema is a domain of motion picture content catering to a viewership interested in imagery that is more provocative than what mainstream audiences desire to see. These types of films are typically considered lowbrow entertainment and have been made in every era, albeit in a limited capacity proportional to the niche audience demand for them. Some time periods see a rise in exploitation film productions in response to a growing demand for such content from a larger share of the broader cinematic audience. This relationship indicates that period-specific cultural factors can cause mainstream audience members to seek out more …

Simulating Emergency Evacuation Response In An Auditorium Space, Anna Lee

Industrial Engineering Undergraduate Honors Theses

The successful execution of emergency evacuations is very important for the protection of the public. Some emergency events, such as fires, can occur with very little warning and turn into a dangerous situation in less than a minute. With high population densities, universities have increased risk involved with evacuations. One specific area that presents high risk is auditorium spaces such as lecture halls with high densities combined with added barriers such as tables and chairs. The ability to assess a building’s emergency preparedness is necessary for keeping the public safe. Simulation is a way to conduct a theoretical event and …

Instance Segmentation-Based Depth Completion Using Sensor Fusion And Adaptive Clustering For Autonomous Vehicle Perception, Mohammad Z. El-Yabroudi

Dissertations

Depth sensing is critical for safe and accurate maneuvering in robotics and self-driving car (SDC) applications. Most recent LiDAR sensors, such as Ouster and Velodyne, offer 360 degrees of scanning at the rate of ten frames per second, making them very appropriate for autonomous driving applications. However, LiDAR point cloud data show many shortcomings, especially its data sparsity and unassigned nature, making it very challenging to utilize in applications such as perception, 3D object detection, 3D scene reconstruction, and simultaneous localization and mapping.

In this study, a novel framework using instance image segmentation and the raw LiDAR data for the …

Coloniality Of Power And The Curriculum Of Violence: Understanding Contemporary Educational Racism In The Americas [La Colonialidad Del Poder Y El Currículum De La Violencia: Comprendiendo El Racismo Educacional Contemporáneo En Las Américas], Noah De Lissovoy, Raúl Olmo Fregoso Bailón

Teaching and Learning Faculty Publications

This study shows how the notion of coloniality of power unveils the existence of a curriculum of violence by considering two contemporary cases in the U.S. and Mexico. Current restrictions on the types of content and activities allowed in civics education concerned with race in the U.S., as well as attacks on normalistas’ bodies and educational institutions in Mexico, show how racism as an international project is attached to a capital system that strategically attempts to disappear (in material and symbolic terms) educators, institutions and curriculum as part of the project of modernity underwritten by a process of coloniality. These …

“I Just Wanted Support”: Examining How Lds Clergy May Effectively Minister To Sexual And Gender Minority Congregants, Samuel J. Skidmore, G. Tyler Lefevor, Adlyn M. Perez-Figueroa, Kristen A. Gonzalez

Psychology Faculty Publications

This study explored why members of the Church of Jesus Christ of Latter-day Saints (LDS) who identify as sexual or gender minorities (SGM) speak with clergy regarding their SGM identities, as well as what LDS SGMs find helpful and unhelpful in these conversations. A sample of 25 current or former LDS SGMs participated in semi-structured interviews, which were analyzed using thematic analysis. Participants reported six overarching reasons for talking with clergy, including church procedures, seeking guidance, seeking emotional comfort, seeking repentance, seeking openness, and other people’s initiation. Participants reported several ways clergy were helpful, including empathic listening, openness, and affirmative …

Mythos, Selma Pena Arenzana

Theses

Mythos is a 2D animated series project developed by Mattea Guldy and Selma Peña. The story revolves around a fairy named Marina and her misfit friends Enki the faun, Demetri the unicorn, and The Kodama, a cute forest spirit. The project consists of a series pitch with a pilot, an episode of the series, a pitch deck, and an animated proof of concept. Our fantastical world aims to represent the diversity of human beings and make the audience question where their beliefs and conceptions come from. The story's main plot is the following: Marina, a fairy descendant from the creature …

Another Cookie, Amanda Kopacz

Theses

Another Cookie is an animated 3D graduate thesis film. It is based on a personal story about a girl who loses her grandfather and learning to live with the lessons he left behind. She has help overcoming this grief from a spirit that represents the humor and happiness of the relationship between the girl and her grandfather. Cookies are at the heart of this story. In the film, there is a plate of cookies at the end of a table full of baking items. Two characters start taking cookies from the plate. A girl and her grandpa are holding a …

Make Your Own Sprites: Aliasing-Aware And Cell-Controllable Pixelization, Zongwei Wu, Liangyu Chai, Nanxuan Zhao, Bailin Deng, Yongtuo Liu, Qiang Wen, Junle Wang, Shengfeng He

Research Collection School Of Computing and Information Systems

Pixel art is a unique art style with the appearance of low resolution images. In this paper, we propose a data-driven pixelization method that can produce sharp and crisp cell effects with controllable cell sizes. Our approach overcomes the limitation of existing learning-based methods in cell size control by introducing a reference pixel art to explicitly regularize the cell structure. In particular, the cell structure features of the reference pixel art are used as an auxiliary input for the pixelization process, and for measuring the style similarity between the generated result and the reference pixel art. Furthermore, we disentangle the …

Visualising Population Dynamics To Examine Algorithm Performance, Mathew J. Walter, David J. Walker, Matthew J. Craven

School of Engineering, Computing and Mathematics

This work assesses the efficacy of evolutionary algorithms (EAs) using an intuitive Multi-Dimensional Scaling (MDS) visualisation of the evolution of a population. We propose the use of Landmark Multi-Dimensional Scaling (LMDS) to overcome computational challenges inherent to visualising many-objective and complex problems with MDS. For the benchmark problems we tested, LMDS is akin to MDS visually, whilst requiring less than 1% of the time and memory necessary to produce an MDS visualisation of the same objective space solutions, leading to the possibility of online visualisations for multiand many-objective optimisation evaluation. Using multi- and many-objective problems from the DTLZ and WFG …

Elucidating Evolutionary Principles With The Traditional Mosuo: Adaptive Benefits And Origins Of Matriliny And “Walking Marriages”, Jose C. Yong, Norman P. Li

Research Collection School of Social Sciences

The Mosuo, arguably the last surviving matrilineal society in China, offers interesting insights into kinship practices that support reproduction. In particular, the modes of courtship and reproduction of the traditional Mosuo revolve around a practice known as walking marriages, which involves no contract or obligations, where the men do not use social status or resources to court women, women do not expect commitment from men, and multiple sexual relationships are permitted for both sexes and seldom incite conflict. Children borne from walking marriages are cared for not so much by fathers but rather their mothers' brothers, and wealth and property …

Man-Machine Dialogues: Computer Representations And Appropriations In The Soviet Union And The United States, Ksenia Tatarchenko

Research Collection College of Integrative Studies

What brought a plurality of information societies into existence? The global process of computerizations went hand in hand with political competition between the First and Second World during the second half of the twentieth century. Non-capitalist information societies were imagined and experienced under the socialistregimes alongside and in interaction with their better-known capitalist counterparts. Both capitalism and socialism asserted the power of the new machines to depict and create a better world.

When Intelligence Hurts And Ignorance Is Bliss: Global Pandemic As An Evolutionarily Novel Threat To Happiness, Satoshi Kanazawa, Norman P. Li, Jose C. Yong

Research Collection School of Social Sciences

Introduction: The savanna theory of happiness posits that it is not only the current consequences of a given situation that affect happiness but also its ancestral consequences, and that the effect of ancestral consequences on happiness is stronger among less intelligent individuals. But what about situations that did not exist in the ancestral environment and thus have no ancestral consequences? Global pandemic is one such situation that has no ancestral analog, and the theory predicts such evolutionarily novel threats to have a negative effect disproportionately on the life satisfaction of more intelligent individuals.Methods: We analyzed prospectively longitudinal data from population …

The Effect Of Executive Function On The Development Of Chronic Pain: A Prospective Longitudinal Study, Wee Qin Ng, Andree Hartanto

Research Collection School of Social Sciences

Increasing evidence suggests a close association between chronic pain and executive function, a set of cognitive processes necessary for goal-directed behaviors. However, there is a dearth of longitudinal studies examining the predictive effect of executive function on the development of chronic pain. Drawing on the cyclical model of executive function and health, we sought to examine how executive function, measured at baseline, may predict chronic pain etiology approximately 9 years later. Using a large-scale dataset of midlife adults (N = 1553) from the MIDUS 2 and 3 (Midlife Development in the United States) studies, we employed multivariate logistic regression to …

From Guo To Tianxia: Linking Two Daoist Theories Of International Relations, Devin K. Joshi

Research Collection School of Social Sciences

This study examines the international relations theory (IRT) of Daoism, one of Asia’s long-standing traditions to have theorized international politics. Drawing upon Laozi’s Dao De Jing, this study elucidates two Daoist IR theories. First, Laozi provides a state-focused guo-based IRT for conducting foreign policy and managing inter-state relations with emphasis on yielding and softness to overcome violence and domination. Second, Laozi offers a Utopian and globalist tianxia-centered IRT based on following the Dao whereby inter-state rivalry is dissolved in favor of peaceful planetary governance in harmony with the natural rhythms of the cosmos. Whereas previous scholarship often concentrates on only …