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Articles 4621 - 4650 of 195906
Full-Text Articles in Entire DC Network
A Large West Antarctic Ice Sheet Explains Early Neogene Sea-Level Amplitude, J. W. Marschalek, L. Zurli, F. Talarico, De Flierdt T Van, P. Vermeesch, A. Carter, F Beny, V. Bout-Roumazeilles, F. Sangiorgi, S. R. Hemming, L. F. Pérez, F. Colleoni, J. G. Prebble, Peer Te Van, M. Perotti, A. E. Shevenell, I Browne, Dk Kulhanek, R. Levy, D Harwood, N. B. Sullivan, S. R. Meyers, E. M. Griffith, C. D. Hillenbrand, E. Gasson, M. J. Siegert, B Keisling, K. J. Licht, G. Kuhn, Jp Dodd, C. Boshuis, Santis L De, Rm Mckay, Jeanine Ash, F Beny, Im Browne, Giuseppe Cortese, Santis L De, Jp Dodd, Oliver M. Esper, Jenny A. Gales, Dm Harwood, Saki Ishino, Ba Keisling, S Kim, S Kim, Dk Kulhanek, Jan Sverre Laberg, R. Mark Leckie, Rm Mckay, J Müller, Mo Patterson, Bw Romans, Oe Romero, F. Sangiorgi, O Seki, Ae Shevenell, Sm Singh, De Sousa Im Cordeiro, St Sugisaki, T Van De Flierdt, Peer Te Van, W Xiao, Z Xiong
A Large West Antarctic Ice Sheet Explains Early Neogene Sea-Level Amplitude, J. W. Marschalek, L. Zurli, F. Talarico, De Flierdt T Van, P. Vermeesch, A. Carter, F Beny, V. Bout-Roumazeilles, F. Sangiorgi, S. R. Hemming, L. F. Pérez, F. Colleoni, J. G. Prebble, Peer Te Van, M. Perotti, A. E. Shevenell, I Browne, Dk Kulhanek, R. Levy, D Harwood, N. B. Sullivan, S. R. Meyers, E. M. Griffith, C. D. Hillenbrand, E. Gasson, M. J. Siegert, B Keisling, K. J. Licht, G. Kuhn, Jp Dodd, C. Boshuis, Santis L De, Rm Mckay, Jeanine Ash, F Beny, Im Browne, Giuseppe Cortese, Santis L De, Jp Dodd, Oliver M. Esper, Jenny A. Gales, Dm Harwood, Saki Ishino, Ba Keisling, S Kim, S Kim, Dk Kulhanek, Jan Sverre Laberg, R. Mark Leckie, Rm Mckay, J Müller, Mo Patterson, Bw Romans, Oe Romero, F. Sangiorgi, O Seki, Ae Shevenell, Sm Singh, De Sousa Im Cordeiro, St Sugisaki, T Van De Flierdt, Peer Te Van, W Xiao, Z Xiong
School of Biological and Marine Sciences
Early to Middle Miocene sea-level oscillations of approximately 40–60 m estimated from far-field records are interpreted to reflect the loss of virtually all East Antarctic ice during peak warmth2. This contrasts with ice-sheet model experiments suggesting most terrestrial ice in East Antarctica was retained even during the warmest intervals of the Middle Miocene. Data and model outputs can be reconciled if a large West Antarctic Ice Sheet (WAIS) existed and expanded across most of the outer continental shelf during the Early Miocene, accounting for maximum ice-sheet volumes. Here we provide the earliest geological evidence proving large WAIS expansions occurred during …
The Effect Of Promotion On Instagram With Psychographics On The Intensity Of Visits At The Ministry Library In Indonesia, Tri Hartanto, Muhammad Azwar
The Effect Of Promotion On Instagram With Psychographics On The Intensity Of Visits At The Ministry Library In Indonesia, Tri Hartanto, Muhammad Azwar
Library Philosophy and Practice (e-journal)
Libraries have an essential role in managing collections to meet the information needs of users. Libraries need to do more intense promotions by optimizing Instagram's social media. This study aims to determine how much influence promotion on Instagram with psychographics has on the Intensity of visits at the ministry library in Indonesia. This research was conducted in the library of the ministry of education and culture, Indonesia. This study uses associative statistics with a quantitative approach. The data analysis used was multiple linear regression to test the hypothesis of the influence of variables X1 and X2 on variable Y. Sampling …
A Scientometric Study Of Journal Of Librarianship & Information Science (Jolis) During 2007-2016, Dinesh Kumari Kundu, Nirmal Kumar Swain
A Scientometric Study Of Journal Of Librarianship & Information Science (Jolis) During 2007-2016, Dinesh Kumari Kundu, Nirmal Kumar Swain
Library Philosophy and Practice (e-journal)
The present study is based on the scientometric analysis of 218 documents published in JoLiS from 2007 to 2016.The study explored various parameters of scientometrics such as total output ; year wise distribution and growth of research output; future growth of publications; degree of collaborations among authors, most prolific author, top ten countries in terms of research output and top cited article of the journal. The study found that most productive years were 2015 and 2016 with 28 (12.84%) publications and the least productive year was 2009 with 15(6.88%) publications. The study explored that the estimated future growth of JoLiS …
Web Content Analysis Of State University Websites Of West Bengal: An Evaluative Study, Ankit Das, Dr. Pritam Gurey
Web Content Analysis Of State University Websites Of West Bengal: An Evaluative Study, Ankit Das, Dr. Pritam Gurey
Library Philosophy and Practice (e-journal)
Now-a-days websites and its services are the most growing and the fast-changing segment, play an important role as an informational gateway for every institution through online mode. The purpose of this paper is to analyse and evaluate the web contents of twenty-six state universities websites of West Bengal selected according to UGC, under Ministry of Education, Government of India and its contribution to global academic knowledge base. After preparing check list, various aspects related to the content of university website are examined; such as accessibility, currency, speed, accuracy, aesthetic value, language, user friendliness, navigation, currency, relevancy, applicability, pertinence and qualitative …
Collaboration Between Librarians And Academics In The Department Of Information Studies For Curriculum Development In Kzn, Petros Pn Dlamini, Bethiweli Mlambo, T Masenya
Collaboration Between Librarians And Academics In The Department Of Information Studies For Curriculum Development In Kzn, Petros Pn Dlamini, Bethiweli Mlambo, T Masenya
Library Philosophy and Practice (e-journal)
The aim of this study is to assess the level of collaboration between librarians and Library and Information Science (LIS) academics for the development of the LIS curriculum, being aware that collaboration is an instructional strategy that positively affects student academic achievement. The term collaboration has become popular concept in areas of life where two or more individuals, organisations, institutions or nation embark upon a mutually agreed process. Collaboration provides the opportunity for experts and researchers to partner and fine-tune thoughts and develop strategies for multi-dimensional thinking towards achieving common and uniform practice. Collaboration between librarians and LIS academics has …
Users’ Satisfaction With Resources And Services Of Public Libraries: A Case Of Govt. Jinnah Public Library Sahiwal, Pakistan, Muhammad Tariq Mr, Ahmad Nawaz Mr, Rais Ahmad Samdani Dr
Users’ Satisfaction With Resources And Services Of Public Libraries: A Case Of Govt. Jinnah Public Library Sahiwal, Pakistan, Muhammad Tariq Mr, Ahmad Nawaz Mr, Rais Ahmad Samdani Dr
Library Philosophy and Practice (e-journal)
Public libraries play a pivotal role in the development of national culture, society, economy and other factors. Users have extreme importance when libraries are discussed. Good resources and services are essentially required for library users. The objective of this study was to evaluate the users’ satisfaction with the resources and services of a public library. Quantitative research approach based on survey method was used to conduct this study. A structured questionnaire was designed to collect the data from the registered members of Government Jinnah Public Library Sahiwal (GJPLS). Convenience sampling technique was applied to approach sample size of this study. …
A Study On Impact Of Library Resource Utilisation And Ict Literacy On Earning Of The Post-Graduate Students Of Assam, India, Arnob Paul, Masuma Ahmed
A Study On Impact Of Library Resource Utilisation And Ict Literacy On Earning Of The Post-Graduate Students Of Assam, India, Arnob Paul, Masuma Ahmed
Library Philosophy and Practice (e-journal)
Information and communication technology, or ICT, is a broad term for information technology that emphasises the importance of unified communications and telecommunications integration, as well as intelligent building management systems and audio-visual systems in modern information technology. ICT refers to all technical tools that are used to manage data and facilitate communication. It consists of computer and network hardware, as well as software and required applications. With the increasing demand for information and communication technology literacy among the young students, it is important to know the impact of ICT literacy on the level of part time income of the students. …
World Changers: Social Justice At The Heart Of Middle School Language Arts Curriculum, Mackenzie Mcclain
World Changers: Social Justice At The Heart Of Middle School Language Arts Curriculum, Mackenzie Mcclain
Honors Theses
English classrooms, at their best, are safe places for adolescents to critically engage with difficult issues presented in novels and the real world. One such issue is human trafficking, which is expected to soon become the world’s most profitable criminal industry (Knudsen, 2015). Incorporating values and instructional approaches from social justice pedagogy, I have designed a sixth-grade language arts unit plan about human trafficking based upon Francesco D’Adamo’s novel, Iqbal (2003). My purpose was to create resources, such as standards-based learning objectives, text sets, lesson plans, and student projects to use in my own classroom, as well as for teachers …
Lindenwood Digest, December 15, 2021, Lindenwood University
Lindenwood Digest, December 15, 2021, Lindenwood University
Lindenwood Digest
The Lindenwood Digest has been a digital employee newsletter since 2009.
Beach Hazards: Riu Funana, Cape Verde, C Stokes, G Masselink, T Scott, L Brodie
Beach Hazards: Riu Funana, Cape Verde, C Stokes, G Masselink, T Scott, L Brodie
School of Biological and Marine Sciences
No abstract provided.
On The Variability Of Flocculated Particle Characteristics In A Shallow Estuary, G Egan, G Chang, Aj Manning, Sg Monismith, Ob Fringer
On The Variability Of Flocculated Particle Characteristics In A Shallow Estuary, G Egan, G Chang, Aj Manning, Sg Monismith, Ob Fringer
School of Biological and Marine Sciences
No abstract provided.
Visual Field Progression In Glaucoma: Comparison Between Poplr And Answers, Iván Marín-Franch, Paul H. Artes, Andrew Turpin, Lyne Racette
Visual Field Progression In Glaucoma: Comparison Between Poplr And Answers, Iván Marín-Franch, Paul H. Artes, Andrew Turpin, Lyne Racette
School of Health Professions
No abstract provided.
The Five Ds Of Outpatient Antibiotic Stewardship For Urinary Tract Infections, Melanie C Goebel, Barbara W Trautner, Larissa Grigoryan
The Five Ds Of Outpatient Antibiotic Stewardship For Urinary Tract Infections, Melanie C Goebel, Barbara W Trautner, Larissa Grigoryan
Faculty, Staff and Students Publications
Urinary tract infections (UTI) are one of the most common indications for antibiotic prescriptions in the outpatient setting. Given rising rates of antibiotic resistance among uropathogens, antibiotic stewardship is critically needed to improve outpatient antibiotic use, including in outpatient clinics (primary care and specialty clinics) and emergency departments. Outpatient clinics are in general a neglected practice area in antibiotic stewardship programs, yet most antibiotic use in the United States is in the outpatient setting. This article provides a comprehensive review of antibiotic stewardship strategies for outpatient UTI in the adult population, with a focus on the "five Ds" of stewardship …
Dread Nation And Deathless Divide, By Justina Ireland. Reviewed By Phillip Fitzsimmons., Phillip Fitzsimmons
Dread Nation And Deathless Divide, By Justina Ireland. Reviewed By Phillip Fitzsimmons., Phillip Fitzsimmons
Mythprint Book Reviews
Mythprint is the quarterly bulletin of the Mythopoeic Society, a nonprofit educational organization devoted to the study, discussion, and enjoyment of myth and fantasy literature, especially the works of J.R.R. Tolkien, C.S. Lewis, and Charles Williams. To promote these interests, the Society publishes three magazines, maintains a World Wide Web site, and sponsors the annual Mythopoeic Conference and awards for fiction and scholarship, as well as local discussion groups.
Half Sick Of Shadows, By Laura Sebastian. Reviewed By Mckenzie Peck, Mckenzie Peck
Half Sick Of Shadows, By Laura Sebastian. Reviewed By Mckenzie Peck, Mckenzie Peck
Mythprint Book Reviews
Mythprint is the quarterly bulletin of the Mythopoeic Society, a nonprofit educational organization devoted to the study, discussion, and enjoyment of myth and fantasy literature, especially the works of J.R.R. Tolkien, C.S. Lewis, and Charles Williams. To promote these interests, the Society publishes three magazines, maintains a World Wide Web site, and sponsors the annual Mythopoeic Conference and awards for fiction and scholarship, as well as local discussion groups.
Democracy And The Media: The Year In C-Span Archives Research, Volume 7, Robert X. Browning
Democracy And The Media: The Year In C-Span Archives Research, Volume 7, Robert X. Browning
The Year in C-SPAN Archives Research
Volume 7 of The Year in C-SPAN Archives Research series focuses on the relationship between democracy and the media. Using the extensive collection of the C-SPAN Video Library, chapters cover Trump political rallies, congressional references of late-night comedy, responses of African American congresswomen to COVID-19 bills, and congressional attacks on the media through floor speeches in the House of Representatives and Senate.
The C-SPAN Video Library is unique because there is no other research collection that is based on video research of contemporary politics. Methodologically distinctive, much of the research uses new techniques to analyze video, text, and spoken words …
The Fall Of Gondolin: Complete Demo Recording, By Paul Corfield Godfrey. Reviewed By David Bratman., David Bratman
The Fall Of Gondolin: Complete Demo Recording, By Paul Corfield Godfrey. Reviewed By David Bratman., David Bratman
Mythprint Book Reviews
Mythprint is the quarterly bulletin of the Mythopoeic Society, a nonprofit educational organization devoted to the study, discussion, and enjoyment of myth and fantasy literature, especially the works of J.R.R. Tolkien, C.S. Lewis, and Charles Williams. To promote these interests, the Society publishes three magazines, maintains a World Wide Web site, and sponsors the annual Mythopoeic Conference and awards for fiction and scholarship, as well as local discussion groups.
Abdominal Paraganglioma In A Patient With Fever Of Unknown Origin, Samantha Sokoloff, Barbara Simon
Abdominal Paraganglioma In A Patient With Fever Of Unknown Origin, Samantha Sokoloff, Barbara Simon
Department of Medicine Faculty Papers
Reaxys Chemistry database information SciVal Topics Funding details
Abstract
Introduction: Paragangliomas have a wide range of clinical presentations. A significant portion of these tumors are discovered as abdominal masses on imaging or palpation in patients without typical symptoms of catecholamine excess [1]. This case reports a 28-year-old female who presented with fever of unknown origin and was found to have an abdominal mass on CT imaging. This mass was biopsied prior to a complete evaluation and confirmed to be a paraganglioma. Case report: We discuss the case of a 28 year-old-female who presented to the Endocrinology office after she was …
Structural Stability Of Short Latency Alfalfa-Based Pastures In The Humid Pampa, Argentina, R. O. Refi, B. Martín
Structural Stability Of Short Latency Alfalfa-Based Pastures In The Humid Pampa, Argentina, R. O. Refi, B. Martín
IGC Proceedings (1977-2023)
The aim of this study was to search the effects of grazing intensity and nitrogen fertilization on the structural stability of a mixed pasture composed by alfalfa (latency group 9), brome grass, tall fescue and white clover, sown in April 1997. Rotational grazing was carried out with dairy cattle with high intensity (HI: up to 3-4 cm) or moderate intensity (LI: up to 8-10 cm), whenever the alfalfa showed basal regrowth. According to a split-plot design, grazing intensities were subdivided to assign three levels of nitrogen fertilization: N0, without fertilization; N1 with 50 kg N/ha per year; and N2 with …
Late Winter Dietary Overlap Among Greater Rheas And Domestic Herbivores On The Argentinean Flooding Pampa, G. Vacarezza, M. S. Cid, F. Milano
Late Winter Dietary Overlap Among Greater Rheas And Domestic Herbivores On The Argentinean Flooding Pampa, G. Vacarezza, M. S. Cid, F. Milano
IGC Proceedings (1977-2023)
This study evaluates the dietary overlap among greater rheas (Rhea americana L.) sheep and cattle in the Flooding Pampa, Buenos Aires, Argentina during late winter, when is observed the lowest forage availability. The work was carried out with the following forage classes (FC): warm and cool season grasses and forbs (legumes and no-legumes). Diet botanical composition was estimated by microanalysis of faeces. Principal Component Analysis and Kulcyznsky´s index of similarity were used for data analysis. Rhea populations selected diets with higher forb percentages. On the contrary, vegetation structure and their own morpho-physiology conditioned cattle to diets almost exclusively gramineous. …
Beef Calf Production Using Year-Round Grazing On Tropical Grass Pasture In Summer Combined With Cool Temperate Grass Pasture In Winter, Y. Nakanishi, K. Shindou, S. Watanabe, K. Yamamoto, K. Hagino
Beef Calf Production Using Year-Round Grazing On Tropical Grass Pasture In Summer Combined With Cool Temperate Grass Pasture In Winter, Y. Nakanishi, K. Shindou, S. Watanabe, K. Yamamoto, K. Hagino
IGC Proceedings (1977-2023)
Bahiagrass (Paspalum notatum Fluegge) showed a poor quality with low crude protein in summer but blood biochemical levels of grazing beef cows were similar to drylot feeding cows except of concentration of urea nitrogen. Italian ryegrass (Lolium multiflorum Lam) showed very good quality with high crude protein (about 20 percentage) in winter. And so, suckler cows gained live weight in winter and suckling calves were showed very high growth rate (daily gain was about 1.0 kg). Total live weight gains of grazing cows were higher than those of drylot feeding cows. Postpartum reproductive performances of grazing cows were …
Winter Grazing And Feeding Systems In Western Canada, Duane H. Mccartney, V. Baron, J. Basarab, E. Okine, G. Lastiwka, A. Depalme, D. Young
Winter Grazing And Feeding Systems In Western Canada, Duane H. Mccartney, V. Baron, J. Basarab, E. Okine, G. Lastiwka, A. Depalme, D. Young
IGC Proceedings (1977-2023)
Beef cow calf producers in Western Canada are looking for methods of extending the grazing season into the winter in order to lower winter feed costs. Dry beef cows were early or late weaned and grazed during the early months of winter on late seeded barley swaths (Hardlum vulgare L.) and compared to cows fed barley silage and free choice barley straw in a feeding yard. The swath grazed barley was late seeded in June and swathed in the silage stage in mid September. Cows successfully swath grazed for three winters from mid November until mid to late February …
Forage Management For Extending The Grazing Season, David W. Koch, C. M. Lux, J. W. Flake
Forage Management For Extending The Grazing Season, David W. Koch, C. M. Lux, J. W. Flake
IGC Proceedings (1977-2023)
Studies were conducted to determine ways to extend grazing season with forages adequate to meet the needs of grazing animals and to reduce the cost of livestock production. Perennial grasses were swathed, windrowed and left in the field until they were winter-grazed with bred heifers. Corn (Zea mays L.) was stockpiled for winter grazing with lambs and ewes. Windrowed grasses increased in acid detergent fiber (ADF) and neutral detergent fiber (NDF) compared with stored hay, but crude protein content, heifer weight gain and body condition change was similar for both forages. An economic value of $218 ha-1 from …
Molecular Cartography Of Residue Pesticides On Grape Surface In 3d By Ambient Ionization Tandem Mass Spectrometry, Hung Su, Tiao-Lai Huang, Cheng-Ting Chi, Yi-Tzu Cho, Chi-Wei Lee, Jingyueh Jeng, Jentaie Shiea
Molecular Cartography Of Residue Pesticides On Grape Surface In 3d By Ambient Ionization Tandem Mass Spectrometry, Hung Su, Tiao-Lai Huang, Cheng-Ting Chi, Yi-Tzu Cho, Chi-Wei Lee, Jingyueh Jeng, Jentaie Shiea
Journal of Food and Drug Analysis
Thermal desorption-electrospray ionization tandem mass spectrometry (TD-ESI/MS/MS) was used to characterize the residual pesticides that were collected from the surface of a grape with metallic sampling probes. Fungicides, insecticides, and miticides were detected, where results were validated by simple solvent extraction followed by gas chromatography tandem mass spectrometry and liquid chromatography tandem mass spectrometry analyses. To explore the distribution of pesticide residues on grape surfaces, 149 locations of a grape surface were collected and followed by TD-ESI/MS/MS analysis. The molecular cartography was then generated from analysis of residual pesticides on the grape surface in 3D.
Variations In Bovine Milk Oligosaccharides After Calving Using P-Aminobenzoic Ethyl Ester Closed-Ring Labeling And Negative Ion Electrospray Lc/Ms/Ms, Han-Ju Chien, Yi-Chun Ma, Yi-Feng Zheng, Cheng-Yu Kuo, Wei-Chen Wang, Guor-Rong Her, Chien-Chen Lai
Variations In Bovine Milk Oligosaccharides After Calving Using P-Aminobenzoic Ethyl Ester Closed-Ring Labeling And Negative Ion Electrospray Lc/Ms/Ms, Han-Ju Chien, Yi-Chun Ma, Yi-Feng Zheng, Cheng-Yu Kuo, Wei-Chen Wang, Guor-Rong Her, Chien-Chen Lai
Journal of Food and Drug Analysis
A strategy was proposed to analyze bovine milk oligosaccharides using p-aminobenzoic ethyl ester (ABEE) closed-ring labeling and C18 capillary liquid chromatography negative ion electrospray tandem mass spectrometry. Linkage specific fragment ions were used to identify oligosaccharide isomers. By constructing the mass chromatograms using linkage specific fragment ions, isomers were differentiated based on m/z values as well as temporal separation provided by liquid chromatography. In addition to disialyllactose and the single isomer lacto-N-neohexaose, four pairs of linkage isomers including 3’/6’-sialyllactose (3’/6’-SL), 3’/6’-sialyllactosamine (3’/6’-SLN), 3’/6’-sialylgalactosyl-lactose (3’/6’-SGL), and lacto-N-tetraose/lacto-N-neotetraose (LNT/LNnT) in bovine milk were investigated. Variations of bovine milk oligosaccharides in a …
Analysis Of Heterocyclic Aromatic Amines Using Selective Extraction By Magnetic Molecularly Imprinted Polymers Coupled With Liquid Chromatography – Mass Spectrometry, Shih-Ci Jhu, Jing-Ying Wang, Hsueh-Ting Wang, Sung-Fang Chen
Analysis Of Heterocyclic Aromatic Amines Using Selective Extraction By Magnetic Molecularly Imprinted Polymers Coupled With Liquid Chromatography – Mass Spectrometry, Shih-Ci Jhu, Jing-Ying Wang, Hsueh-Ting Wang, Sung-Fang Chen
Journal of Food and Drug Analysis
Heterocyclic aromatic amines (HCAs) are highly carcinogenic and mutagenic chemicals. This study reports on the development of magnetic molecularly imprinted polymers (MMIPs) for the purification and quantification of HCAs. A novel magnetic molecularly imprinted polymer was successfully prepared using a surface molecular imprinting method using functionalized Fe particles as the magnetic cores. 2-Amino-3-methylimidazo[4,5-f]quinoline (IQ) was used as a molecular template; methacrylic acid (MAA), ethylene glycol dimethyl acrylate (EGDMA), 2, 2′-Azobis (2-methylpropionitrile) were used as the functional monomer, crosslinker, and initiator, respectively. The use of the template/functional monomer/crosslinking agent at a ratio of 1:4:20 resulted in a product with better adsorption …
The Impact Of The Rare Disease And Orphan Drug Act In Taiwan, Ning-Chun Hsiang, Weng-Foung Huang, Churn-Shiouh Gau, Teng-Wen Tsai, Lin-Chau Chang
The Impact Of The Rare Disease And Orphan Drug Act In Taiwan, Ning-Chun Hsiang, Weng-Foung Huang, Churn-Shiouh Gau, Teng-Wen Tsai, Lin-Chau Chang
Journal of Food and Drug Analysis
The Rare Disease and Orphan Drug Act (the Act) was enacted in 2000 in Taiwan for the facilitation of the research, development, and accessibility of orphan drugs and special nutritional foods; for the prevention and early diagnosis of rare diseases; and for providing intensive care for patients with rare diseases. The aim was to investigate the impact of the Act on the availability and use of orphan drugs in Taiwan in the hope of identifying the remaining challenges and possible solutions to assist future policy making, which may be applicable in other countries as well. The information and statistics for …
Determination Of Quetiapine And Its Metabolites In Plasma By Field-Enhanced Sample Stacking, Tai-Ling Liu, Li-Shan Fang, Jing-Ru Liou, Jia-Shan Dai, Yen-Ling Chen
Determination Of Quetiapine And Its Metabolites In Plasma By Field-Enhanced Sample Stacking, Tai-Ling Liu, Li-Shan Fang, Jing-Ru Liou, Jia-Shan Dai, Yen-Ling Chen
Journal of Food and Drug Analysis
Quetiapine is an atypical antipsychotic drug that can be used to treat mental disorders, including schizophrenia, bipolar disorder and Alzheimer's disease. Quetiapine is mainly converted into the active metabolites of norquetiapine and 7-hydroxyquetiapine by the liver enzymes CYP3A4 and CYP2D6. In this study, liquid-liquid extraction (LLE) was used as a sample pretreatment method to eliminate interferences in plasma. tert-Butyl methyl ether was chosen as the extraction solvent. Field-enhanced sample injection (FESS), an online preconcentration technique, was used to analyze quetiapine and its metabolites norquetiapine and 7-hydroxyquetiapine in plasma. The optimal separation condition was 120 mM phosphate (pH 4.0) containing …
Quantitative Analysis Of Fragrance Allergens In Various Matrixes Of Cosmetics By Liquid-Liquid Extraction And Gc-Ms, Chia-Hui Lu, Ming-Chih Fang, Yu-Zi Chen, Shou-Chieh Huang, Der-Yuan Wang
Quantitative Analysis Of Fragrance Allergens In Various Matrixes Of Cosmetics By Liquid-Liquid Extraction And Gc-Ms, Chia-Hui Lu, Ming-Chih Fang, Yu-Zi Chen, Shou-Chieh Huang, Der-Yuan Wang
Journal of Food and Drug Analysis
Fragrances are the most common chemicals in cosmetics to which people expose every day. However, the unwanted allergic reactions such as contact dermatitis caused by direct contact with fragrances may happen. In Directive 2003/15/EC of the EU, cosmetic product containing one or more of 26 fragrance allergens must be declared on the package label. In addition, commission regulation (EU) 2017/1410 amending Annexes II and III of cosmetic regulation 1223/2009 restricted fragrance chemical of methyl eugenol, and prohibited Lyral, atranol, chloroatranol to be used in cosmetic. In this study, an efficient and sensitive GC-MS method for 3 banned fragrances, 26 fragrance …