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2021

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Understanding Drivers Of Coronavirus Disease 2019 (Covid-19) Racial Disparities: A Population-Level Analysis Of Covid-19 Testing Among Black And White Populations, Aaloke Mody, Kristin Pfeifauf, Cory Bradley, Branson Fox, Matifadza G. Hlatshwayo, Will Ross, Vetta Sanders-Thompson, Karen Joynt Maddox, Mat Reidhead, Mario Schootman, William G. Powderly, Elvin H. Geng Jan 2021

Understanding Drivers Of Coronavirus Disease 2019 (Covid-19) Racial Disparities: A Population-Level Analysis Of Covid-19 Testing Among Black And White Populations, Aaloke Mody, Kristin Pfeifauf, Cory Bradley, Branson Fox, Matifadza G. Hlatshwayo, Will Ross, Vetta Sanders-Thompson, Karen Joynt Maddox, Mat Reidhead, Mario Schootman, William G. Powderly, Elvin H. Geng

Open Access Publications

BACKGROUND: Disparities in coronavirus disease 2019 (COVID-19) testing-the pandemic's most critical but limited resource-may be an important but modifiable driver of COVID-19 inequities.

METHODS: We analyzed data from the Missouri State Department of Health and Senior Services on all COVID-19 tests conducted in the St Louis and Kansas City regions. We adapted a well-established tool for measuring inequity-the Lorenz curve-to compare COVID-19 testing rates per diagnosed case among Black and White populations.

RESULTS: Between 14/3/2020 and 15/9/2020, 606 725 and 328 204 COVID-19 tests were conducted in the St Louis and Kansas City regions, respectively. Over time, Black individuals consistently …


The Free And Cued Selective Reminding Test Predicts Braak Stage, Ellen Grober, Qi Qi, Lynn Kuo, Jason Hassenstab, Richard J Perrin, Richard B Lipton Jan 2021

The Free And Cued Selective Reminding Test Predicts Braak Stage, Ellen Grober, Qi Qi, Lynn Kuo, Jason Hassenstab, Richard J Perrin, Richard B Lipton

2020-Current year OA Pubs

BACKGROUND: The ultimate validation of a clinical marker for Alzheimer's disease (AD) is its association with AD neuropathology.

OBJECTIVE: To identify clinical measures that predict pathology, we evaluated the relationships of the picture version of the Free and Cued Selective Reminding Test (pFCSRT + IR), the Mini-Mental State Exam (MMSE), and the Clinical Dementia Rating scale Sum of Boxes (CDR-SB) to Braak stage.

METHODS: 315 cases from the clinicopathologic series at the Knight Alzheimer's Disease Research Center were classified according to Braak stage. Boxplots of each predictor were compared to identify the earliest stage at which decline was observed and …


Stages Of Objective Memory Impairment Predict Alzheimer's Disease Neuropathology: Comparison With The Clinical Dementia Rating Scale-Sum Of Boxes, Ellen Grober, Qi Qi, Lynn Kuo, Jason Hassenstab, Richard J Perrin, Richard B Lipton Jan 2021

Stages Of Objective Memory Impairment Predict Alzheimer's Disease Neuropathology: Comparison With The Clinical Dementia Rating Scale-Sum Of Boxes, Ellen Grober, Qi Qi, Lynn Kuo, Jason Hassenstab, Richard J Perrin, Richard B Lipton

2020-Current year OA Pubs

BACKGROUND: The ultimate validation of a clinical marker for Alzheimer's disease (AD) is its association with AD neuropathology.

OBJECTIVE: To examine how well the Stages of Objective Memory Impairment (SOMI) system predicts intermediate/high AD neuropathologic change and extent of neurofibrillary tangle (NFT) pathology defined by Braak stage, in comparison to the Clinical Dementia Rating (CDR) Scale sum of boxes (CDR-SB).

METHODS: 251 well-characterized participants from the Knight ADRC clinicopathologic series were classified into SOMI stage at their last assessment prior to death using the free recall and total recall scores from the picture version of the Free and Cued Selective …


The Gendered Impact Of Droughts On Household Decision Making: Evidence From Uganda, Fiona Onyango, Andrew Hobbs Jan 2021

The Gendered Impact Of Droughts On Household Decision Making: Evidence From Uganda, Fiona Onyango, Andrew Hobbs

Master's Theses

Do female headed households lose/ sell more of their livestock in the event of a drought as compared to households headed by males? We address this question through an analysis of the combination of Living Standards Measurement study Integrated surveys on Agriculture dataset on Uganda using data from the period 2011-2016 and NDVI & Weather data. We carry out both OLS and fixed effects estimations. Our OLS Results are consistent with the theory of Consumption smoothing while we do not find evidence of any gendered effects from both the OLS and IV estimations.


Do Conditional Cash Transfers Increase School Enrollment? Evidence From Brazil, Jeanette L. Silvernale Jan 2021

Do Conditional Cash Transfers Increase School Enrollment? Evidence From Brazil, Jeanette L. Silvernale

Master's Theses

Conditional cash transfer programs have been widely deployed across the globe. They seek to bolster human capital by providing benefits contingent upon a variety of actions such as school attendance and regular health checkups. Bolsa Familia is the most extensive conditional cash transfer program, serving 46 million Brazilian citizens. Despite its expansive size, there have been seldom large-scale micro evaluations of the program. Limited data has resulted in small sample sizes drawn from a single point in time. Our study diverges from the rest and utilizes a novel administrative dataset with an overall sample of nearly 60 million and a …


Temperature Effects On Prevalence Of Sexually Transmitted Infections Among At-Risk Female Sex Workers In India, Rajshri Suresh Jan 2021

Temperature Effects On Prevalence Of Sexually Transmitted Infections Among At-Risk Female Sex Workers In India, Rajshri Suresh

Master's Theses

Vulnerability to climate change varies depending on the baseline climate, sensitivity to given exposure, and the presence of social, political, cultural, and institutional inequalities that influence access to essential resources of livelihood, particularly among informal labor market participants. Within the risky informal labor market, the transient nature of sex work implies that sex workers suffer disproportional losses in health, income, protection, and other aspects of general well-being as a result of the effects of climate anomalies. In this paper, I investigate the effect of temperature on the prevalence of sexually transmitted infections in a high-risk population of female sex workers …


Teaching The Bible, Steelman Library, Camilla Belfon Jan 2021

Teaching The Bible, Steelman Library, Camilla Belfon

Syllabus Repository

No abstract provided.


Galaxy And Mass Assembly (Gama): The Interplay Between Galaxy Mass, Sfr, And Heavy Element Abundance In Paired Galaxy Sets, L. E. Garduno, M. A. Lara-Lopez, O. Lopez-Cruz, A. M. Hopkins, M. S. Owers, K. A. Pimbblet, Benne Holwerda Jan 2021

Galaxy And Mass Assembly (Gama): The Interplay Between Galaxy Mass, Sfr, And Heavy Element Abundance In Paired Galaxy Sets, L. E. Garduno, M. A. Lara-Lopez, O. Lopez-Cruz, A. M. Hopkins, M. S. Owers, K. A. Pimbblet, Benne Holwerda

Faculty and Staff Scholarship

We study the star formation rate (SFR), stellar mass (M), and the gas metallicity (Z) for 4636 galaxy pairs using the Galaxy And Mass Assembly (GAMA) survey. Our galaxy pairs lie in a redshift range of 0


Kentucky And The Thoroughbred Industries: Prospects And Challenges As Gambling Stagnates, Thomas E. Lambert Jan 2021

Kentucky And The Thoroughbred Industries: Prospects And Challenges As Gambling Stagnates, Thomas E. Lambert

Faculty and Staff Scholarship

Over the last 15 to 20 years or so horse racing has seen declines in wagering and fan attendance throughout the US. Because of this, the number of races, horses per race, the number of thoroughbred farms, and new thoroughbreds bred and born each year for about the last 10 to 12 years have also declined. The decline in wagering has occurred despite simulcasting of races, online betting, and gambling machines which employ films of past races (historical horse racing machines). Those racetracks doing well are usually part of larger casino and entertainment complexes (racinos). Kentucky, which has one of …


The Benefits Of Being A Suicidal Curmudgeon: Emil Cioran On Killing Yourself, Glenn M. Trujillo Jr Jan 2021

The Benefits Of Being A Suicidal Curmudgeon: Emil Cioran On Killing Yourself, Glenn M. Trujillo Jr

Faculty and Staff Scholarship

Emil Cioran offers novel arguments against suicide. He assumes a meaningless world. But in such a world, he argues, suicide and death would be equally as meaningless as life or anything else. Suicide and death are as cumbersome and useless as meaning and life. Yet Cioran also argues that we should contemplate suicide to live better lives. By contemplating suicide, we confront the deep suffering inherent in existence. This humbles us enough to allow us to change even the deepest aspects of ourselves. Yet it also reminds us that our peculiar human ability—being able to contemplate suicide—sets us above anything …


Analyzing Perceptions Of Citizen Science As Part Of An International Learning Experience, Katelyn Marie Miner Jan 2021

Analyzing Perceptions Of Citizen Science As Part Of An International Learning Experience, Katelyn Marie Miner

Dissertations and Theses @ UNI

This study focused on a perceptions-based citizen science project that emphasizes meaning over measurement. Specifically, student perceptions of citizen science in a unique location, rather than the specific data outcomes of the water quality citizen science activity were analyzed. Many researchers have used citizen science participants to collect samples from water sources around them, increasing the use of mass data collection for scientific purposes.This study was a mixed-methods design, using triangulation of the pre-survey, modified focus group, and post-survey. The goal was to gauge the perceptions of participants in perceived benefits and gains before and after participating in a water …


Effects Of Transcranial Direct Current Stimulation Of The Motor Cortex On Cycling Time Trial Performance And Prefrontal Cortex Activation, Abigail Hope Auten Jan 2021

Effects Of Transcranial Direct Current Stimulation Of The Motor Cortex On Cycling Time Trial Performance And Prefrontal Cortex Activation, Abigail Hope Auten

Dissertations and Theses @ UNI

Transcranial direct current stimulation (tDCS) is a neuromodulatory technique that delivers low levels of a constant current via scalp electrodes to specifically targeted areas of the brain. The effects of tDCS on whole-body exercise performance has been of interest in recent literature. Purpose: To investigate if tDCS, administered via Halo Sport, influences time trial performance in trained cyclists, and if changes in exercise performance are associated with prefrontal cortex (PFC) activation and/or muscle oxygenation (SmO2). Methods: Twelve recreationally trained cyclists volunteered to participate in two 10km time trials following 20 minutes of tDCS or a sham condition. Results: T-tests showed …


Examining Individual Differences In Attitudes Toward The Insanity Defense, Dominique M. Kornely Jan 2021

Examining Individual Differences In Attitudes Toward The Insanity Defense, Dominique M. Kornely

Dissertations and Theses @ UNI

The purpose of the present study was to examine how individual differences in stigma against people who are mentally ill, free will beliefs, just world beliefs, and sentencing goals are associated with attitudes toward the insanity defense. Because there are many misconceptions about what the insanity defense is, and how it is actually used as a sentence, the Not Guilty by Reason of Insanity (NGRI) plea may be underutilized due to public opinions reflecting misunderstanding and/or possible biases (Perlin, 2017). Understanding the relation between individual beliefs and attitudes about the insanity defense would help to better understand potential biases present …


Quantifying Carbon Sequestration For Riparian-Zone Restoration In Ecuador, Paula Carvalho De Castro Jan 2021

Quantifying Carbon Sequestration For Riparian-Zone Restoration In Ecuador, Paula Carvalho De Castro

Dissertations and Theses @ UNI

Carbon sequestration supported by carbon pricing and carbon offset programs has the potential to mitigate the risks associated with environmental change. Riparian-zone restoration, beyond enriching degraded ecosystems, promotes carbon sequestration. With that premise, this study aims to estimate and compare how much carbon is captured and stored using six riparian-zone restoration scenarios for the Northwestern part of the Pichincha Province in Ecuador and the economic value of the respective carbon. The InVEST Carbon Storage and Carbon Sequestration Model which integrates land cover maps, carbon pools, and economic value of carbon in currency units was used to quantify the amount of …


Model Evidence Links (Mels) And The Impact Of Critical Thinking On Open Ended Responses, James Gregory Zabel Jan 2021

Model Evidence Links (Mels) And The Impact Of Critical Thinking On Open Ended Responses, James Gregory Zabel

Dissertations and Theses @ UNI

The purpose of this dissertation, which was conducted in a rural school district that is equidistant from three major urban areas in central Iowa, and employed an action research methodology, was to examine the relationship between graphic organizer use and critical thinking. A multitude of studies have provided evidence that graphic organizers aid in the recall and understanding of basic facts in the lower grade levels; however, little research exists that supports a connection between graphic organizer use and the ability of students to recall information used on open-ended critical thinking assessments or the ability to create what Bickel and …


Exploring The Experiences Of One Team Of Teachers: Well-Being And Navigating The Demands Of The Education Profession, Abby Weiland Jan 2021

Exploring The Experiences Of One Team Of Teachers: Well-Being And Navigating The Demands Of The Education Profession, Abby Weiland

Dissertations and Theses @ UNI

Much is changing in K-12 education contexts, including an emphasis on performativity and accountability (Au, 2016; Connell, 2009). Against this backdrop, teacher burnout and attrition have been the focus of numerous studies, including examination of organizational structures and factors contributing to burnout (Buckley et al., 2005; Konu et al., 2010). Insufficient attention has been given to how teachers are able to navigate the demands of this profession (Matteucci et al., 2017; Wilcox & Lawson, 2018). Efforts to retain teachers should not only emphasize factors associated with burnout or attrition, but also how they are affected by the systems in place, …


Translation Into Spanish, Cultural Adaption And Content Validity Of The Bristol Copd Knowledge Questionnaire, Vilma Gómez Jan 2021

Translation Into Spanish, Cultural Adaption And Content Validity Of The Bristol Copd Knowledge Questionnaire, Vilma Gómez

Dissertations and Theses @ UNI

COPD is the major cause of respiratory mortality world-wide. The treatment of COPD includes education and self-management to enable patients to control the symptoms, handle the treatment, manage the physical and psychosocial consequences of the disease, and adopt the necessary lifestyle changes for dealing with a chronic condition. Measurement of results of interventions is necessary to demonstrate their effectiveness. Questionnaires help clinicians measure the level of knowledge before and after treatments. However, there are no questionnaires available in Colombian Spanish to measure knowledge of Chronic Obstructive Pulmonary Disease (COPD). This research resulted in the translation into Spanish, cultural adaptation, and …


Fraudulent Transfer As A Tort, David G. Carlson Jan 2021

Fraudulent Transfer As A Tort, David G. Carlson

Articles

Fraudulent transfer law has historically been an in rem right of a creditor to property fraudulently received by a third party. In a minority of states, courts have treated fraudulent transfers as creating an in personam liability of the transferring debtor, the recipient, and any other third party who "conspired" with the transferor to achieve the transfer. This Article examines the wisdom of this modern trend and finds it wanting. The United States Supreme Court in 1861 was correct: fraudulent transfers are not wrongs. They merely create in rem rights.


William Leonard Culp Collection - Accession 1737, William Leonard Culp, Winthrop University, Winthrop Training School, Lee Miller, Leslee Elliott, Whitney Carter Jan 2021

William Leonard Culp Collection - Accession 1737, William Leonard Culp, Winthrop University, Winthrop Training School, Lee Miller, Leslee Elliott, Whitney Carter

Manuscript Collection

This collection is a series of transcriptions of interviews conducted of Bill Culp by one Lee Miller and students Whitney Carter and Leslee Elliott, dating from 8 Sept. 2003, through to the end of that Fall semester. The interviews themselves are primarily focused upon discussing the history of Winthrop, and in particular, the buildings at Winthrop, along with many of Mr. Culp’s own anecdotes. The interviews were conducted to “capture the history of Winthrop according to the 50+ years of Mr. Culp’s involvement with Winthrop.” These interviews offer a great glimpse of Winthrop’s history spanning from Winthrop Founder and first …


Defining Who Is An Employee After A.B.5: Trading Uniformity And Simplicity For Expanded Coverage, Edward A. Zelinsky Jan 2021

Defining Who Is An Employee After A.B.5: Trading Uniformity And Simplicity For Expanded Coverage, Edward A. Zelinsky

Articles

My assessment of California’s A.B.5 differs from the evaluation advanced by the advocates and opponents of that legislation: I conclude that A.B.5 made a significant but limited expansion of the coverage of California labor law but at a notable cost. Even as A.B.5 broadened the reach of the Golden State’s labor protections, A.B.5 also made the definition of "employee” more complex and less uniform. Those seeking federal or state legislation like A.B.5 confront the same trade-off under which greater coverage is achieved at the expense of more complexity and less uniformity in the definition of who is an employee. The …


Blockchain Neutrality, Samuel N. Weinstein Jan 2021

Blockchain Neutrality, Samuel N. Weinstein

Articles

Blockchain technology is transforming how markets work. Blockchains eliminate the need for trusted gatekeepers like banks to execute, verify, and record transactions. In the financial markets, their disruptive potential threatens both Wall Street banks and Silicon Valley venture capitalists. How blockchain technology is regulated will determine whether it encourages or inhibits competition. Some blockchain applications present serious fraud and systemic risks, complicating regulation. This Article explores the antitrust and competition policy challenges blockchain presents and proposes a regulatory strategy, modeled on Internet regulation and net neutrality principles, to unlock blockchain’s competitive potential. It contends that financial regulators should promote blockchain …


The Rise Of Decentralized Autonomous Organizations: Opportunities And Challenges, Aaron J. Wright Jan 2021

The Rise Of Decentralized Autonomous Organizations: Opportunities And Challenges, Aaron J. Wright

Articles

The article explores the rise of Decentralized Autonomous Organizations (DAOs), highlighting their potential to transform traditional organizational structures through blockchain technology and smart contracts. DAOs offer operational efficiencies, such as decentralized governance and transparent decision-making, but face significant legal challenges, including lack of recognition, liability concerns, and regulatory uncertainties. The article argues that U.S. business law, with its emphasis on private ordering, could accommodate DAOs, but legal adaptations are necessary to address their unique characteristics and ensure widespread adoption.


New Federalism And Civil Rights Enforcement, Alexander A. Reinert, Joanna C. Schwartz, James E. Pfander Jan 2021

New Federalism And Civil Rights Enforcement, Alexander A. Reinert, Joanna C. Schwartz, James E. Pfander

Articles

Calls for change to the infrastructure of civil rights enforcement have grown more insistent in the past several years, attracting support from a wide range of advocates, scholars, and federal, state, and local officials. Much of the attention has focused on federal-level reforms, including proposals to overrule Supreme Court doctrines that stop many civil rights lawsuits in their tracks. But state and local officials share responsibility for the enforcement of civil rights and have underappreciated powers to adopt reforms of their own. This Article evaluates a range of state and local interventions, including the adoption of state law causes of …


Police Prosecutions And Punitive Instincts, Kate Levine Jan 2021

Police Prosecutions And Punitive Instincts, Kate Levine

Articles

This Article makes two contributions to the fields of policing and criminal legal scholarship. First, it sounds a cautionary note about the use of individual prosecutions to remedy police brutality. It argues that the calls for ways to ease the path to more police prosecutions from legal scholars, reformers, and advocates who, at the same time, advocate for a dramatic reduction of the criminal legal system’s footprint, are deeply problematic. It shows that police prosecutions legitimize the criminal legal system while at the same time displaying the same racism and ineffectiveness that have been shown to pervade our prison-backed criminal …


Erisa Defined Benefit Plans Are Not "Trust" Worthy, Stewart E. Sterk Jan 2021

Erisa Defined Benefit Plans Are Not "Trust" Worthy, Stewart E. Sterk

Articles

No abstract provided.


Title Insurance: Protecting Property At What Price?, Stewart E. Sterk Jan 2021

Title Insurance: Protecting Property At What Price?, Stewart E. Sterk

Articles

The real property recording system is designed to protect purchasers and mortgagees against defects in title. Navigating that system is beyond the capacity of most laymen; historically, purchasers hired lawyers and other professionals to identify and eliminate title risks. Institutional lenders, however, sought more protection than a lawyer's opinion could provide, leading to the development of title insurance. Title insurance, unlike most other insurance, is focused not on risk spreading but on risk elimination. By examining title before issuing a policy, a title insurer minimizes the likelihood of a successful claim by an insured whose title turns out to be …


Malondialdehyde Acetaldehyde Adducts (Maa-Adducts) Direct Distinctive Pro-Inflammatory Responses In Endothelial And Macrophage Cell Lines, Patrick J. Opperman, Michael J. Duryee, Ted R. Mikuls, Geoffrey M. Thiele, Dahn L. Clemens, Daniel R. Anderson Jan 2021

Malondialdehyde Acetaldehyde Adducts (Maa-Adducts) Direct Distinctive Pro-Inflammatory Responses In Endothelial And Macrophage Cell Lines, Patrick J. Opperman, Michael J. Duryee, Ted R. Mikuls, Geoffrey M. Thiele, Dahn L. Clemens, Daniel R. Anderson

EMET Projects

Chronic inflammation plays a critical role in the pathogenesis of atherosclerosis. At present, the mechanism(s) by which inflammation contributes to this disease isnot entirely understood. Inflammation is known to induce oxidative stress, of which one consequence is lipid peroxidation. This process leads to the production of malondialdehyde (MDA), which can subsequently break down to form acetaldehyde (AA). These two aldehyde by-products can covalently interact with the ε-amino group of lysineswithin proteins and lipoproteins leading to the formation of highly immunogenic malondialdehyde-acetaldehyde adducts (MAA-adducts). The aim of this study was to determine the in-vitro cytokine response of endothelial cells and macrophages …


The Induction Of Autoimmune Arthritis And Sex Differences In Mice Impact The Lung Inflammatory Response To Repetitive Inhalant Organic Dust Extract Exposures, Kathryn Rentfro, Geoffrey M. Thiele, Katherine Janike, Amy J. Nelson, Michael J. Duryee, Bryant R. England, Debra J. Romberger, Joseph Carrington, Dong Wang, Benjamin J. Swanson, Lynell W. Klassen, Ted R. Mikuls, Jill A. Poole Jan 2021

The Induction Of Autoimmune Arthritis And Sex Differences In Mice Impact The Lung Inflammatory Response To Repetitive Inhalant Organic Dust Extract Exposures, Kathryn Rentfro, Geoffrey M. Thiele, Katherine Janike, Amy J. Nelson, Michael J. Duryee, Bryant R. England, Debra J. Romberger, Joseph Carrington, Dong Wang, Benjamin J. Swanson, Lynell W. Klassen, Ted R. Mikuls, Jill A. Poole

EMET Projects

Asthma, chronic bronchitis and COPD are common adverse respiratory health effects among persons exposed to agriculture organic dust work environments.

  • Occupational inhalant exposures have been increasingly associated with the risk of rheumatoid arthritis (RA) disease development, particularly among males. Agriculture workers have increased risk of RA and generalized bone disease.
  • Chronic lung disease is associated with production of characteristic autoantibodies associated with RA (e.g.anti-citrullinated antibodies), even in absence of RA disease.
  • The mechanistic link between pulmonary inflammation and arthritis (and vice versa) remains poorly understood. Animal models are lacking.


Differential Microglial Responses Induced By N-A-Synuclein-Specific Effector T Cell Clones, Sean C. Selko, Rebecca A. Wilshusen, Katherine E. Olson, R. Lee Mosley Jan 2021

Differential Microglial Responses Induced By N-A-Synuclein-Specific Effector T Cell Clones, Sean C. Selko, Rebecca A. Wilshusen, Katherine E. Olson, R. Lee Mosley

EMET Projects

Parkinson's disease (PD) is a neurodegenerative movement disorder in which symptoms derive from deficits in dopamine neurotransmitter levels secondary to loss of dopaminergic neurons in the substantia nigra pars compacta (SNpc) associated with misfolding and accumulation of α−synuclein. Neuroinflammation via microglia and T effector cells (Teffs) contribute to dopaminergic neuronal cell death. Recognition of cytokine profiles of pro-inflammatory microglia is not well understood and serve as potential therapeutic targets to reduce neuroinflammation. Recent studies demonstrated a novel Th17.1 Teff clonotype increases neurotoxicity. The aim of this study was to demonstrate in vitro cytokine responses by BV-2 microglia induced by Th1, …


Constructing A Learning Community: One Medical Schools Needs Assessment, Kelsey Woods, Brian P. Boerner, Jenenne A. Geske Jan 2021

Constructing A Learning Community: One Medical Schools Needs Assessment, Kelsey Woods, Brian P. Boerner, Jenenne A. Geske

EMET Projects

No abstract provided.