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2021

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Birth Trauma: A Mixed-Methods Investigation, Grace Baptie Jan 2021

Birth Trauma: A Mixed-Methods Investigation, Grace Baptie

Other Faculty of Health Theses

Approximately one-third of women appraise their childbirth experience as traumatic and many women experience symptoms of posttraumatic stress disorder (PTSD) as a result. Whilst earlier work concentrated on prevalence and risk factors of clinically significant trauma, recent research focuses on the large group of women who experience childbirth as traumatic but do not necessarily meet the threshold for PTSD. This thesis comprises a mixed-methods design to investigate predisposing factors associated with presentation of postnatal posttraumatic stress (PTS) symptoms and the appraisal of childbirth as a traumatic experience. Specifically, this thesis aims to address the following questions: What perinatal risk factors …


High Throughput Sequencing Technologies In Blood Group Genotyping And Applications In Transfusion Medicine: Establishment Of Rh Genes Reference Allele Sequences, Wajnat Ali Tounsi Jan 2021

High Throughput Sequencing Technologies In Blood Group Genotyping And Applications In Transfusion Medicine: Establishment Of Rh Genes Reference Allele Sequences, Wajnat Ali Tounsi

Other Faculty of Health Theses

The Rh blood group system (ISBT004) is the second most important blood group after ABO and the most polymorphic one, with 55 antigens encoded by two genes, RHD and RHCE. The two genes are homologous and located on chromosome 1 with 10 coding exons. This research uses next generation sequencing (NGS) on Ion Torrent Personal Genome Machine™ (Ion PGM™) to sequence the Rh genes (RHD, RHCE, RHAG) using overlapping Long Range-PCR (LR-PCR) amplicons. The aim was to study different RHD and RHCE alleles present in the population to establish reference RHD and RHCE allele sequences by utilising the analysis of …


Developing And Embedding A Feasible Digital Health Champion Scheme Into The Nursing Curriculum: A Collaborative Action Research Approach, Toni Page Jan 2021

Developing And Embedding A Feasible Digital Health Champion Scheme Into The Nursing Curriculum: A Collaborative Action Research Approach, Toni Page

Other Faculty of Health Theses

Technology can help meet the health needs of service users and carers. However, both local communities and our future workforce require support in becoming aware of and in using such technologies. Universities must do more to prepare our future nurses but these students can also support local communities in the transition to this digital future. This PhD aimed to develop and embed a feasible model offering nursing students the opportunity to support their local community in health technology, while listening to and learning from people’s experiences of healthcare. This study comprised three collaborative action research cycles with multiple stakeholders using …


The Effects Of Mindfulness Meditation On Attention Regulation, Paul Sharpe Jan 2021

The Effects Of Mindfulness Meditation On Attention Regulation, Paul Sharpe

Other Faculty of Health Theses

The research in this thesis tested the claim that mindfulness meditation regulates attention. Attention regulation was operationalised as an improvement on alerting, orienting or executive attention measured using the Attention Network Test (ANT), or a reduction in the attentional blink (AB) effect, measured using a Rapid Serial Visual Presentation (RSVP) task. Chapter 1 reviews the relevant literature. Chapters 2 and 3 report five experiments which tested the effects of Focused Attention Meditation (FAM) on the ANT. In Chapter 2, no effects of brief FAM were found on the ANT in novices (Experiment 1), or long-term meditators (Experiments 2 and 3). …


Dll4 And Jag1 In The Glioblastoma Response To Temozolomide Chemotherapy, Carly Bunston Jan 2021

Dll4 And Jag1 In The Glioblastoma Response To Temozolomide Chemotherapy, Carly Bunston

Other Faculty of Health Theses

Introduction: Glioblastoma multiforme is the most common aggressive primary malignant brain tumour in adults. The current gold standard treatment comprises of surgery followed by radiotherapy and adjuvant temozolomide (TMZ) chemotherapy. Prognosis is poor, with a median survival of 14.6 months following diagnosis. Treatment often fails due to intrinsic or acquired TMZ resistance of a small population of cells termed glioma cancer stem cells (GCSCs). A promising target for glioblastoma therapy is the Notch signalling pathway, which can be suppressed using gamma-secretase inhibitors such as dibenzazepine (DBZ). We investigated the effects of the Notch ligands, Delta-like 4 (DLL4) and Jagged-1 (JAG1) …


Music And The Brain: Composing With The Electroencephalogram, Rachel Horrell Jan 2021

Music And The Brain: Composing With The Electroencephalogram, Rachel Horrell

Other Faculty of Arts, Humanities and Business Theses

The field of brain-computer music interfaces have been expanding ever since the first development in the 1960s. Although many brain-computer music interfaces have been developed for the purpose of composing music, these systems have not been accessible to musicians due to the use of complex programming and signal processing mathematics. In addition, these systems have often focused on the process of composing music by allowing for specific note selection, or the formation of structure. While these systems are beneficial for those who cannot compose music the traditional way, such as those with motor disabilities, they do not offer a new …


Social And Commercial Enterprise Interactions: Insights From Uk Business Incubators, Eleanor Browne Jan 2021

Social And Commercial Enterprise Interactions: Insights From Uk Business Incubators, Eleanor Browne

Other Faculty of Arts, Humanities and Business Theses

With numbers of social enterprises in the UK continuing to grow and innovate, this research responds to the scarcity of information surrounding social and commercial enterprises co-located in business incubators, and asks: how and why do social and commercial enterprises interact in a business incubator? The research provides qualitative insights for a rich understanding of the network dynamics, subtle interactions and influences that occur amongst peer groups of mixed social and commercial enterprises during business incubation. Drawing on social capital theory, the study utilises multiple methods through a practice-led, qualitative methodology. Employing novel observation techniques in business incubation and semi-structured …


A Practice-As-Research Project Utilizing Butler’S (1990) Feminist/ Post-Structuralist Theory Of Gender Performativity, As Well As Connells (2001) System Of Hegemony, Complicity, And Subordination To Interrogate The Formation Of Toxic Masculinities Through Practice-As-Research And Live Art Methodologies, Charlie Cornforth Jan 2021

A Practice-As-Research Project Utilizing Butler’S (1990) Feminist/ Post-Structuralist Theory Of Gender Performativity, As Well As Connells (2001) System Of Hegemony, Complicity, And Subordination To Interrogate The Formation Of Toxic Masculinities Through Practice-As-Research And Live Art Methodologies, Charlie Cornforth

Other Faculty of Arts, Humanities and Business Theses

In the past twenty years or so, the concept of masculinity has come under increasing scrutiny. What used to constitute as socially acceptable behaviour for men to engage in, has increasingly become challenged by developments such as the MeToo movement. There are now stable grounds to argue that there is such thing as a toxic masculinity, an understanding that has been brought about through a series of questions that ask what grounds masculinity is constructing its position of authority and power upon, what behaviours associated with masculinity are bringing harm to both society as a whole, the individual man and …


Norman Lewis On The Peripheral: The Relationship Of An African American Artist And The Abstract Expressionist Movement Through The Decades, 1930-1950, Ione Church Jan 2021

Norman Lewis On The Peripheral: The Relationship Of An African American Artist And The Abstract Expressionist Movement Through The Decades, 1930-1950, Ione Church

Other Faculty of Arts, Humanities and Business Theses

Abstract Expressionism took the American Art World by storm. However, the contribution of African America artist Norman Lewis is often overshadowed. In recent years Lewis has come to light as a significant artist involved with this movement, although there has been little research identifying this. My research identifies three decades of Lewis’s career as a working artist from 1930- 1950 and examines how the style of his work, politics and society form ideals on his position with the art group. The current history on Lewis is placed within the post colonial theory of race, my research will give a greater …


Governance Of High Sea Mediterranean Marine Protected Areas From A Maltese Perspective, Christopher Cousin Jan 2021

Governance Of High Sea Mediterranean Marine Protected Areas From A Maltese Perspective, Christopher Cousin

Other Faculty of Arts, Humanities and Business Theses

The conservation of marine resources is gaining importance as more research is carried out leading to an increase in public awareness through campaigns and news. One conservation tool that is attracting more attention is commonly referred to as marine protected area (MPA). This tool has been used over many years but its use is increasing. There are various legal instruments that either obligate or encourage the use of MPAs. MPAs can be applied in all areas irrespective of the jurisdiction. However, jurisdiction of the area where a MPA is to be designated, influences the nature of regulations with which the …


Philip Guston’S Absurd And The Sisyphean Affirmation In The Battle For Existentialism, Jason Blacklock Jan 2021

Philip Guston’S Absurd And The Sisyphean Affirmation In The Battle For Existentialism, Jason Blacklock

Other Faculty of Arts, Humanities and Business Theses

Abstract Philip Guston’s Absurd and the Sisyphean Affirmation of the Battle for Existentialism – By Jason Blacklock This dissertation offers an Existentialist interpretation of the life and work of Philip Guston. Discourse regarding avant-garde New York School artists and their knowledge and manipulation of Existentialism has an illustrious rollcall. Dore Ashton and Harold Rosenberg, amongst others have added their powers of exegesis to contemporary work by Mark Rothko, Jackson Pollock, and Willem de Kooning. Amongst this canon of America’s great twentieth century Abstract-Expressionists Philip Guston’s work is often noted, but rarely aligned fully with Existentialist and particularly Absurdist values. I …


Lut Lut Lut A Collection Of Poems Accompanied By A Critical Thesis: The Poetics Of The Dérive And Détournement With Reference To The Situationists, Susan Howe And Peter Riley, Sam Kemp Jan 2021

Lut Lut Lut A Collection Of Poems Accompanied By A Critical Thesis: The Poetics Of The Dérive And Détournement With Reference To The Situationists, Susan Howe And Peter Riley, Sam Kemp

Other Faculty of Arts, Humanities and Business Theses

This project investigates the role of the artistic techniques of the dérive and détournement in the work of contemporary poets Susan Howe and Peter Riley, exploring the ways in which these poets adapt, develop and draw inspiration from Situationist avant-garde practices of the mid to late twentieth century. The study consists of two chapters, preceded and followed by an introduction and conclusion. My introduction introduces the key features of the Situationist theory of psychogeography, a radical walking technique aimed at undermining the spectacle of urban commercialism in 1950s Paris, and demonstrates how the frameworks of the dérive and détournement, key …


William Blake’S Selfhood And The Atomistic Materialism Of Lucretius’ De Rerum Natura, Joshua Schouten De Jel Jan 2021

William Blake’S Selfhood And The Atomistic Materialism Of Lucretius’ De Rerum Natura, Joshua Schouten De Jel

Other Faculty of Arts, Humanities and Business Theses

This thesis demonstrates for the first time the way in which William Blake aligned his idiosyncratic concept of the Selfhood – the lens through which the despiritualised subject beholds the material world – with the atomistic materialism of the Epicurean school as it was transmitted through the first-century BC Roman poet and philosopher Lucretius’ De Rerum Natura. Not only will I argue that Blake was aware of classical atomistic cosmogony and sense-based epistemology, but that he systematically mapped postlapsarian existence onto the philosophical framework of Epicurean cosmogony. As a result, when the subject succumbs to the Selfhood and once the …


Light Dance: Beyond The Dichotomy Of Light And Vision, Seth Riskin Jan 2021

Light Dance: Beyond The Dichotomy Of Light And Vision, Seth Riskin

School of Art, Design and Architecture Theses

ABSTRACT Light Dance: Beyond the Dichotomy of Light and Vision Seth Riskin This practice-based dissertation focuses on Light Dance, an original artistic practice developed by the author that, in reducing light to its core elements in a setting devoid of other sources of illumination, centers the equivalence of light and vision in experience. Moving with projection instruments attached to his body, the artist articulates geometrically elemental light forms on the boundaries of the room. Through unique artistic technologies and methods, Light Dance creates a visual environment in which light is perceived as a reflexive experience of vision, an inversion of …


Ideas Exchange: Design And The Post Bio-Tech-Body, Agatha Haines Jan 2021

Ideas Exchange: Design And The Post Bio-Tech-Body, Agatha Haines

School of Art, Design and Architecture Theses

This thesis situates speculative design as a valuable tool for thinking about design issues and the body. Bringing together historical, theoretical criticism and practice to show that speculative design is intimately linked with the body. The thesis’ arguments build on the basis that both the body and design have gone through a processes of anatomisation: they have been dissected, separated and segmented into parts and terms. Those parts and terms are then ordered in a fashion which may not necessarily be advantageous intra-disciplinarily, that is for collaborations and discussions within a discipline. A different anatomisation is proposed for more contemporary …


Sense And Sensing: A Critical Enquiry Into Relations Between Hearing-Impaired Children, Vision And Photography, Kevin Robinson Jan 2021

Sense And Sensing: A Critical Enquiry Into Relations Between Hearing-Impaired Children, Vision And Photography, Kevin Robinson

School of Art, Design and Architecture Theses

This thesis explores and critiques attitudes and assumptions related to hearing-impaired, school-level students and their engagement with the educational discipline of photography. It is not uncommon to find that hearing-impaired children are described as visual learners. This thesis argues that the conceptualisation of children as visual learners merely reflects a wider discourse that aims to legitimise a certain practice of schooling as normative. In appearing as common-sense and value neutral, the discourse has the tendency to perpetuate the marginalisation of those senses deemed less noble and the pedagogical insistence on a premise that posits a link between looking, seeing and …


Place And Identity In Italian Photography Through A Study Of The Town Of Lugo, Luca Nostri Jan 2021

Place And Identity In Italian Photography Through A Study Of The Town Of Lugo, Luca Nostri

School of Art, Design and Architecture Theses

This research is framed by the specific context of Italian photography since the late 1970s, which has defined its own aesthetic and cultural identity in relation to the idea of place. The definitive reference point for this context is the group project Viaggio in Italia conceived and curated by photographer Luigi Ghirri and presented in 1984, when an exhibition of three hundred photographs was held in Bari and a catalogue for the project was published. Viaggio in Italia brought together a generation of photographers who were creating a new cultural atmosphere around photography in Italy: they shared a new and …


Prosthetic Realities, Prosthetic Futures: Challenging The Status Quo Of External Breast Prosthesis Design, Rosie Brave Jan 2021

Prosthetic Realities, Prosthetic Futures: Challenging The Status Quo Of External Breast Prosthesis Design, Rosie Brave

School of Art, Design and Architecture Theses

This practice-based research identifies the need and opportunity to update the design approach used in the production of external breast prostheses (EBP) for women post mastectomy. Spurred by accounts of some women’s negative experiences with their EBP, this research took influence from colour psychology, emotional design and consumer psychology to explore the potential to create a satisfying and transformative product and user-experience. Drawing on grounded theory, design ethnography and human-centred design practices, an iterative, empathic and participant-centred design process and methodology emerged. Insights from interviews, cultural probes, co-design activities and solo practice were combined to inform the making of speculative …


Intuitive Interventions: Constructing Documentary Cinematic Narratives, Heidi Morstang Jan 2021

Intuitive Interventions: Constructing Documentary Cinematic Narratives, Heidi Morstang

School of Art, Design and Architecture Theses

The argument in this summary concerns intuition as creative decision method in observational documentary film practice and is based upon three films produced, directed, edited and published by the author: In Transit [2011]; Prosperous Mountain [2013]; and Pseudotachylyte [2019]. The films are created with digital technologies employing state of the art High Definition Video cameras, and digital post-production software . This summary will use reflection and analysis to make explicit three aspects of the documentary cinematic process of creation: image, sound, and edit. It will highlight where a space is created to facilitate intuition. The summary will revisit some processes …


Deciphering The Silence: A Literary Journey To Alice E. Kober, Regina Dürig Jan 2021

Deciphering The Silence: A Literary Journey To Alice E. Kober, Regina Dürig

School of Art, Design and Architecture Theses

On Thursday, 28 September 2017, I embarked upon my Journey to Alice Kober: 48 hours in trains taking me from New York City, where she had lived all her life, to Austin, Texas, where everything that she left behind is stored today. 48 hours of shades of green and mustardy yellow, 48 hours of train whistles, drip coffee and blunt panic attacks from being tucked away under the plastic roof of the compartment at night. 48 hours of hope and expectations regarding the archive material, of finding what has been lost. My journey to Alice Kober’s archive, to her still-existing …


A Relational Ecology Of Photographic Practices: Towards A Non-Anthropocentric Approach To Photography, Jacqueline Knight Jan 2021

A Relational Ecology Of Photographic Practices: Towards A Non-Anthropocentric Approach To Photography, Jacqueline Knight

School of Art, Design and Architecture Theses

This thesis argues that as photography’s technological basis has become more complex and increasingly detached from human vision, a thicker account of photographic practice that moves away from humanist discourse and single authorship can assist in demonstrating a continuity between film and new technological photographic practices. It revisits key concepts in documentary photography such as the ‘decisive moment’ through the filter of particular historical, technological and philosophical ideas that have informed the critical engagement with photography as a media of representation. It reconsiders some orthodox assumptions about photography including the idea that photography is fundamentally a human-centred practice and that …


The Liminal Event And Its Symbols: On The Intersection Of Human And Technology, Blanka Deroko Jan 2021

The Liminal Event And Its Symbols: On The Intersection Of Human And Technology, Blanka Deroko

School of Art, Design and Architecture Theses

This thesis is an exploration of practical and theoretical modes of constituting hybrid subjectivities on the intersection of human and technology. Taking as a point of departure the posthuman and postphenomenological perspectives, I develop an approach to articulating hybrid subjectivities, where the distributed human and nonhuman entities come together in a relational way, expressing hybrid agencies. This thesis explores an emergent affective dimension in technological spaces, which provide a sensory stimulation to the human enabling a sense of presence in the distributed and virtual space. Further, I demonstrate a systematic manner, in which an integrated liminal event between the human …


How Progressive Was The Representation Of Physical Disability Within Mainstream Film In The 1990s, Given The Increased Awareness About Disability During The Decade?, Connor David Ruse Jan 2021

How Progressive Was The Representation Of Physical Disability Within Mainstream Film In The 1990s, Given The Increased Awareness About Disability During The Decade?, Connor David Ruse

School of Art, Design and Architecture Theses

This dissertation will explore the representation of physical disability in mainstream films in the 1990s, determining that this onscreen representation was only slightly progressive in nature. It is based on a qualitative analysis of sixteen characters with disabilities in fifteen mainstream films released between 1987 and 1999. The observations from this analysis were compiled into a database examining: the type of impairment a character had, the character’s screen time, the disability terminology used within the film and common tropes used to tell the character’s narrative within the film. Using the database and supportive sources, like interviews with the films’ casts …


Social Sculpture: A Plastic Process Of Mutual Transformation, Veronica Marina Fazzio Welf Jan 2021

Social Sculpture: A Plastic Process Of Mutual Transformation, Veronica Marina Fazzio Welf

School of Art, Design and Architecture Theses

Joseph Beuys, the originator of the term ‘Social Sculpture’, stated that the objects he made were stimulators for the formation of thoughts, i.e. that they were intended to mold or to shape thoughts. Beuys believed that the essence of Social Sculpture was to shape and mold the world by working with invisible materials to make new thoughts. His aim was to develop an evolutionary process to share his ideas about the universal nature of plasticity, and thus the ability we all have to constantly transform. This practice as research Ph.D. explores Social Sculpture as a contemporary process of transformation. The …


Exploring And Understanding Patterns Of Emotions In The Overall Sound Energy Of The Human Voice In A Natural Environment With And Through An Interactive Installation And Vr Immersive Videos, Paola Lopreiato Jan 2021

Exploring And Understanding Patterns Of Emotions In The Overall Sound Energy Of The Human Voice In A Natural Environment With And Through An Interactive Installation And Vr Immersive Videos, Paola Lopreiato

School of Art, Design and Architecture Theses

In today’s era we can say that human reality is often reliant on or intersected with computers. The need of improved communication with devices in a natural way has arisen and led to development of interactive systems. The new channel for detecting emotions presented in this thesis is not so much important for humans as it is for computers that still don’t have human capabilities of recognising emotions. The vision that drives this research project is of an interactive kind of art through which it is possible to implement and enhance our knowledge of emotions in relation to sound, assisted …


Syncretic Practices Between Art And Architecture: Towards A Critical Epistemic Practice For Social Engagement., Alejandro Quinteros Jan 2021

Syncretic Practices Between Art And Architecture: Towards A Critical Epistemic Practice For Social Engagement., Alejandro Quinteros

School of Art, Design and Architecture Theses

This thesis proceeds from an analysis and a critical assessment of socially engaged spatial practices that have arisen from the convergence, intersections and conflicts between public, social art, and architecture’s spatial practices; specifically, those situated within informal settlements of marginalized communities in Latin America. Through a literature review, the thesis identifies the persistence of a number of overarching misconceptions informing the design thinking of art and architecture’s spatial practices. This research is geographically framed in Latin America. The thesis develops within the contextual arena of informality as a vernacular practice in the informal settlements of marginalized communities at the borderlands …


The Role Of Autophagy In Protecting Periodontium Integrity, And Lipopolysaccharide-Induced Osteoclast Differentiation, Portia Grayson Jan 2021

The Role Of Autophagy In Protecting Periodontium Integrity, And Lipopolysaccharide-Induced Osteoclast Differentiation, Portia Grayson

Other Faculty of Health Theses

The periodontium is a dynamic tissue that undergoes constant remodeling to maintain its structure and function. There is much evidence in the literature that autophagy can be activated by both mechanical stretching and inflammation, however the mechanisms involved are highly context dependent. Autophagy may also be important for bone remodeling in the oral cavity. Two scenarios where bone remodeling is key to the physiological outcome are orthodontic tooth movement and inflammatory-induced periodontal disease. This thesis aims to investigate the hypothesis that autophagy is involved in bone remodeling during orthodontic tooth movement and periodontal disease. While the stem cells concerned in …


Regulation Of The Expression And Lysine Acetylation Of Pro-Inflammatory Molecules By Lipid-Modifying Enzyme (Lpcat2) In Raw264.7 Cells, Victory Ibigo Poloamina Jan 2021

Regulation Of The Expression And Lysine Acetylation Of Pro-Inflammatory Molecules By Lipid-Modifying Enzyme (Lpcat2) In Raw264.7 Cells, Victory Ibigo Poloamina

Other Faculty of Health Theses

Lysophosphatidylcholine Acyltransferases (LPCATs) are Lipid modifying enzymes that significantly regulate changes in the glycerophospholipid components of the macrophage membrane phospholipid bilayer. LPCAT2 is a subtype of LPCAT that regulates inflammatory responses to infection by lipopolysaccharides and lipopeptides. LPCAT2 co-localises with TLR4 and prevents its translocation to the signalling site (lipid rafts) of macrophage membranes. The first response to inflammation involves infiltration of macrophages to the infected site, where they fight infection by phagocytosing the microbial pathogen. Changes in the macrophage membrane phospholipid bilayer are essential for phagocytosis and receptor signalling. Regulation of protein acylation is also an integral mechanism for …


The Psychology Of Anxiety & Pain In Fibromyalgia, Anna Kharko Jan 2021

The Psychology Of Anxiety & Pain In Fibromyalgia, Anna Kharko

Other Faculty of Health Theses

Understanding pain is integral to understanding fibromyalgia, a chronic musculoskeletal pain condition of undetermined aetiology, and for which no single successful medical therapy exists. Most of what is known about fibromyalgia pain comes from psychophysical research of central sensitisation, a phenomenon of abnormally amplified pain following disruptions in the central nervous system. Anxiety has been long theorised to mediate this centralised pain, but its contribution is yet to be characterised. This thesis presents a multimodal investigation of pain perception under different manifestations of anxiety in both fibromyalgia-diagnosed and pain-free cohorts. Chapter 3 presented the findings from the first study in …


Because You’Re Worth The Risks: Acts Of Oppositional Courage As Symbolic Messages Of Relational Value To Transgender Employees, Christian Thoroughgood, Katina Sawyer, Jennica R. Webster Jan 2021

Because You’Re Worth The Risks: Acts Of Oppositional Courage As Symbolic Messages Of Relational Value To Transgender Employees, Christian Thoroughgood, Katina Sawyer, Jennica R. Webster

Management Faculty Research and Publications

Achieving greater social equity in organizations often depends on majority members taking risks to challenge the status quo on behalf of their colleagues with stigmatized identities. But, how do employees enact courageous behavior in this regard, and what are the social implications of these courageous acts on stigmatized group members who witness them at work? To begin examining these questions, we conducted 4 studies using qualitative and quantitative data collected from 428 transgender employees. Drawing on the core principles of sociometer theory, we argue that these acts of oppositional courage serve an important symbolic function in the eyes of transgender …