Digital Commons Network^™

All God's Children: An Exploratory Study Of Factors To Promote Inclusion Of Autistic Children Within Local Church Congregations, David John Scott Quel

Doctoral Dissertations and Projects

The purpose of this phenomenological study was to understand the gap that exists within the literature concerning the parent’s perspective for incorporating Autistic individuals into the life of the church. The theory guiding this study is Maslow’s hierarchy of needs. In Maslow’s hierarchy, there are five level of needs. These areas are physical needs, security needs, love and belonging, esteem needs and self-actualization. These are the most basic needs whether someone is disabled, has special needs, or has no problems at all. The problem remains, far too often, those individuals who are on the Autistic spectrum are looked at as …

Choosing A Magnesium Fertilizer For Pasture And Hay Fields, Bruce M. Loyd

Faculty & Staff Scholarship

WVU-Extension fact sheet

The Lead, December 2021, Lindenwood University

The Lead

The Lead is an electronic newsletter produced by the Lindenwood College of Education & Human Services.

A Study Of Support For The Bereaved In The Local Congregation, Ngoy Nadine Ilunga

Doctoral Dissertations and Projects

The bereaved often face the ongoing challenges of grief with little support from the Church. This study aimed to resource the Church with practical methodologies to help congregants cope with grief. The study examined the troubling issues the bereaved experience after the death of a loved one. Survey data was collected from ten United Methodist members and had lost an immediate family member within the past five years. The measure consisted of interviews and questionnaires. An email and a verbal announcement during church worship service built the sample. Findings reveal that approximately 90% of participants experienced grief and emotional effects …

Teaching Intentional Discipleship In An Age Of Moral Relativism, David Cruz Martinez

Doctoral Dissertations and Projects

Teaching Intentional Discipleship in an Age of Moral Relativism is essential to counteracting the downward trend of morality, religious affiliation, and church growth in America. In the church where discipleship and fulfilling the Great Commission is becoming more of an option versus a necessity, the fruit of unintentional discipleship has contributed to the transformation of America into an age of moral relativism with no end in sight unless the church reverts to its first love of the Great Commission. The project will accentuate the statistics that demonstrate the current statistical decline of church attendance in the western world and explain …

A Study Of Hunger Relief-Based Outreach As A Model Of Church Growth For The Unattractional Church: The Gospel Grocery Wagon, Jerry Wayne Vineyard

Doctoral Dissertations and Projects

The purpose of the research project is to create a strategy for Under Over Fellowship to engage the immediate low socio-economic, cross-cultural, and multi-racial community with the Gospel of Jesus Christ and to see those who make professions of faith in Jesus Christ become active members of Under Over Fellowship. This model of church growth will be facilitated through the combination of servant evangelism and long-term hunger relief. This method will provide a comfortable and non-confrontational way for members of Under Over Fellowship to build relationships and share the gospel with the residents of the low-income apartment complexes and trailer …

The Roddey Mcmillan Record - December 1, 2021, Winthrop University

The RMR 2020-2029

The Roddey McMillan Record (RMR) is Winthrop’s monthly multicultural student publication. The RMR has been a significant voice of the minority population of the Winthrop community since its creation by Gail Harris in April 1986. It promotes awareness and understanding of issues concerning minorities for the prosperity of the entire Winthrop community. The purpose of the RMR is to shine light on the many diverse cultures at Winthrop, focusing on issues, concerns and happenings of those who represent the multicultural community on campus. The Roddey McMillan Record is named after Dr. Cynthia Roddey and Atty, Sheila McMillan. Cynthia Roddey was …

Temporal Evolution Of The Pcvco2–Paco2/Cao2–Ccvo2 Ratio Vs Serum Lactate During Resuscitation In Septic Shock, Shyam Madabhushi, Anjan Trikha, Rahul K. Anand, Rashmi Ramachandran, Preet M. Singh, Vimi Rewari

Open Access Publications

No abstract provided.

Comparison Of Machine Learning Clustering Algorithms For Detecting Heterogeneity Of Treatment Effect In Acute Respiratory Distress Syndrome: A Secondary Analysis Of Three Randomised Controlled Trials, Pratik Sinha, Alexandra Spicer, Kevin L Delucchi, Daniel F Mcauley, Carolyn S Calfee, Matthew M Churpek

Open Access Publications

BACKGROUND: Heterogeneity in Acute Respiratory Distress Syndrome (ARDS), as a consequence of its non-specific definition, has led to a multitude of negative randomised controlled trials (RCTs). Investigators have sought to identify heterogeneity of treatment effect (HTE) in RCTs using clustering algorithms. We evaluated the proficiency of several commonly-used machine-learning algorithms to identify clusters where HTE may be detected.

METHODS: Five unsupervised: Latent class analysis (LCA), K-means, partition around medoids, hierarchical, and spectral clustering; and four supervised algorithms: model-based recursive partitioning, Causal Forest (CF), and X-learner with Random Forest (XL-RF) and Bayesian Additive Regression Trees were individually applied to three prior …

Efficacy And Safety Of Avapritinib In Advanced Systemic Mastocytosis: Interim Analysis Of The Phase 2 Pathfinder Trial, Jason Gotlib, Andreas Reiter, Stephen T Oh, Et Al

Open Access Publications

Advanced systemic mastocytosis (AdvSM) is a rare, KIT D816V-driven hematologic neoplasm characterized by mast cell infiltration and shortened survival. We report the results of a prespecified interim analysis of an ongoing pivotal single-arm phase 2 trial (no. NCT03580655 ) of avapritinib, a potent, selective KIT D816V inhibitor administered primarily at a once-daily starting dose of 200 mg in patients with AdvSM (n = 62). The primary endpoint was overall response rate (ORR). Secondary endpoints included mean baseline change in AdvSM-Symptom Assessment Form Total Symptom Score and quality of life, time to response, duration of response, progression-free survival, overall survival, changes …

Demographic And Mental Health Assessments In The Adolescent Brain And Cognitive Development Study: Updates And Age-Related Trajectories, Deanna M Barch, Nicole R Karcher, Et Al

Open Access Publications

The Adolescent Brain Cognitive Development (ABCD) Study of 11,880 youth incorporates a comprehensive range of measures assessing predictors and outcomes related to mental health across childhood and adolescence in participating youth, as well as information about family mental health history. We have previously described the logic and content of the mental health assessment battery at Baseline and 1-year follow-up. Here, we describe changes to that battery and issues and clarifications that have emerged, as well as additions to the mental health battery at the 2-, 3-, 4-, and 5-year follow-ups. We capitalize on the recent release of longitudinal data for …

How The Value Of The Environment Controls Persistence In Visual Search, Michael R. Traner, Ethan S. Bromberg-Martin, Ilya E. Monosov

Open Access Publications

Classic foraging theory predicts that humans and animals aim to gain maximum reward per unit time. However, in standard instrumental conditioning tasks individuals adopt an apparently suboptimal strategy: they respond slowly when the expected value is low. This reward-related bias is often explained as reduced motivation in response to low rewards. Here we present evidence this behavior is associated with a complementary increased motivation to search the environment for alternatives. We trained monkeys to search for reward-related visual targets in environments with different values. We found that the reward-related bias scaled with environment value, was consistent with persistent searching after …

Identification Of Histone Deacetylase Inhibitors With (Arylidene)Aminoxy Scaffold Active In Uveal Melanoma Cell Lines, Susanna Nencetti, Doretta Cuffaro, Elisa Nuti, Lidia Ciccone, Armando Rossello, Marina Fabbi, Flavio Ballante, Gabriella Ortore, Grazia Carbotti, Francesco Campelli, Irene Banti, Rosaria Gangemi, Garland R Marshall, Elisabetta Orlandini

Open Access Publications

Uveal melanoma (UM) represents an aggressive type of cancer and currently, there is no effective treatment for this metastatic disease. In the last years, histone deacetylase inhibitors (HDACIs) have been studied as a possible therapeutic treatment for UM, alone or in association with other chemotherapeutic agents. Here we synthesised a series of new HDACIs based on the SAHA scaffold bearing an (arylidene)aminoxy moiety. Their HDAC inhibitory activity was evaluated on isolated human HDAC1, 3, 6, and 8 by fluorometric assay and their binding mode in the catalytic site of HDACs was studied by molecular docking. The most promising hit was …

Fabrication And Evaluation Of Bilateral Helmholtz Radiofrequency Coil For Thermo-Stable Breast Image With Reduced Artifacts, Young Han Lee, Kyu-Ho Song, Jaemoon Yang, Won Jun Kang, Keum Sil Lee, Min Jung Kim, Eun-Kyung Kim, Dan Heo, Bo-Young Choe, Jin-Suck Suh

Open Access Publications

PURPOSE: The positron emission tomography (PET)-magnetic resonance (MR) system is a newly emerging technique that yields hybrid images with high-resolution anatomical and metabolic information. With PET-MR imaging, a definitive diagnosis of breast abnormalities will be possible with high spatial accuracy and images will be acquired for the optimal fusion of anatomic locations. Therefore, we propose a PET-compatible two-channel breast MR coil with minimal disturbance to image acquisition which can be used for simultaneous PET-MR imaging in patients with breast cancer.

MATERIALS AND METHODS: For coil design and construction, the conductor loops of the Helmholtz coil were tuned, matched, and subdivided …

Establishment Of The In Vitro Culture And Plant Regeneration Of Anubias Barteri Var. Nana 'Mini', Kuan-Hung Lin, Chih-Peng Kuo, Li-Ru Chen

The Philippine Agricultural Scientist

Anubias barteri is an ornamental aquatic plant of economic importance worldwide. Effective removal of contaminants has been a major problem for the in vitro propagation of A. barteri. Hydrogen peroxide (H₂O₂) was applied as a pre-disinfectant to treat rhizome bud explants of A. barteri var. nana ‘Mini’ followed by disinfection with mercuric chloride (HgCl₂) to eliminate in vitro contamination. However, application of 0.1% HgCl₂ for 5 min without pre-disinfecting with H₂O₂ significantly reduced the contamination rate to 44.4% compared to other combinations. Moreover, in vitro shoots of A. barteri …

Serine/Threonine Protein Phosphatase 1-Α (Stpp1-Α) From Black Tiger Shrimp, Penaeus Monodon, An Immune-Related Gene, Jacqueline Marjorie Pereda, Neil Andrew Bascos, Mudjekeewis Santos

The Philippine Agricultural Scientist

Reversible protein phosphorylation is a significant regulatory mechanism in many cellular functions, such as the dephosphorylation of Serine/Threonine protein residues catalyzed by protein phosphatase. In this study, the full-length STPP1-α gene from Penaeus monodon was cloned, characterized, and analyzed for its constitutive expression in WSSV-negative P. monodon organs. The gene was originally an isotig isolated from the gills of P. monodon that survived WSSV infection. PmSTPP1-α gene (GenBank: KX385833) has a total of 2 171 bp, with a 990 open reading frame (ORF) that encodes 329 amino acids (aa), sharing a 93% sequence identity with human Serine/Threonine PP1-α …

Rearing Silver Therapon Leiopotherapon Plumbeus (Teleostei: Terapontidae) Larvae Using Euryhaline Rotifers As Starter Food, Frolan A. Aya, Vicar Stella Nillasca, Luis Maria B. Garcia

The Philippine Agricultural Scientist

The silver therapon Leiopotherapon plumbeus is an important but dwindling freshwater food commodity in the Philippine freshwater habitats. The influence of feeding regimes on growth performance and survival of first-feeding silver therapon larvae fed euryhaline rotifers (Brachionus rotundiformis and B. plicatilis) as starter food was examined. Larvae at two days post-hatch (DPH) (1.93 ± 0.07 mm; 200 larvae/basin) were initially reared on rotifers for 12 days followed by Artemia nauplii from 14 to 35 DPH as follows: (A) B. rotundiformis from 2-13 DPH; (B) B. rotundiformis from 2-7 DPH and Moina micrura from 8-13 DPH; and (C) B. …

Global Forces Of Change: Implications For Forest-Poverty Dynamics, Priya Shyamsundar, Laura Aileen Sauls, Jennifer Zavaleta Cheek, Kira Sullivan-Wiley, J.T. Erbaugh, P. P. Krishnapriya

Natural Resource Management Faculty Publications

This article examines global trends likely to influence forests and tree-based systems and considers the poverty implications of these interactions. The trends, identified through a series of expert discussions and review of the literature, include: (i) climatic impacts mediated through changes in forests, (ii) growth in commodity markets, (iii) shifts in private and public forest sector financing, (iv) technological advances and rising interconnectivity, (v) global socio-political movements, and (vi) emerging infectious diseases. These trends bring opportunities and risks to the forest-reliant poor. A review of available evidence suggests that in a business-as-usual scenario, the cumulative risks posed by these global …

Correction To: Response Shift In Patient-Reported Outcomes: Definition, Theory, And A Revised Model, Antoine Vanier, Frans J. Oort, Leah Mcclimans, Nikki Ow, Bernice G. Gulek, Jan R. Böhnke, Mirjam Sprangers, Véronique Sébille, Nancy Mayo, Response Shift-In Sync Working Group

Faculty Publications

No abstract provided.

Tennessee Birth Defects Data Report 2014-2018, Tennessee. Department Of Health.

Tennessee Birth Defects

No abstract provided.

Juvenile Report, December 2021, Tennessee. Department Of Correction.

Juvenile Reports

No abstract provided.

Tennessee Felon Population Update, December 2021, Tennessee. Department Of Correction.

Felon Population Reports

No abstract provided.

Annual Report On Energy-Efficient Purchasing, Central Procurement Office, Fy 2020-2021, Tennessee. Department Of General Services.

Energy-Efficiency Reports

No abstract provided.

Tennessee Labor Market Report, December 2021, 2020 Small Area Income And Poverty Estimates, Tennessee. Department Of Labor & Workforce Development.

Labor Market Reports

No abstract provided.

2020 Tennessee Census Of Fatal Occupational Injuries, The Survey Of Occupational Injuries And Illnesses, Tennessee. Department Of Labor & Workforce Development.

Occupational Injuries

No abstract provided.

Enzyme Kinetics, Molecular Docking, And In Silico Characterization Of Canary Seed (Phalaris Canariensis L.) Peptides With Ace And Pancreatic Lipase Inhibitory Activity, Uriel Urbizo-Reyes, Andrea M. Liceaga, Lavanya Reddivari, Kee-Hong Kim, Joseph M. Anderson

Department of Food Science Faculty Publications

The bioactivity of canary seed peptides (CSP) towards metabolism-regulating enzymes was evaluated. Peptides with angiotensin-converting enzyme (ACE), dipeptidyl peptidase IV (DPP-IV), and pancreatic lipase activity remained stable (p < 0.05) to simulated gastrointestinal digestion (SGD). CSP-SGD were transported efficiently (>10%) through the Caco-2 monolayer, indicating absorption through the intestinal epithelium. Lineweaver-Burk plots demonstrated that CSP-SGD act as mixed-type inhibitors for DPP-IV and α-glucosidase. Furthermore, CSP-SGD were potent as antihypertensive and antiobesity agents. Molecular docking and in silico analyses were targeted to understand CSP-SGD interactions with ACE and pancreatic lipase. ACE-inhibitory peptides (LHPQ, QTPHQ, KPVPR, and ELHPQ) acted as non-competitive inhibitors by destabilization of the transition state and Zn(II) coordination in …

The Uniform Soybean Tests: Northern Region 2021, Guohong Cai, Adam Brock

Uniform Soybean Tests Northern Region

The purpose of The Uniform Soybean Tests is to critically evaluate the best of the experimental soybean lines developed by federal and state research personnel in the U.S. and Canada, for their potential release as new varieties. A test is established for each of ten maturity groups. Uniform Test 00 includes maturity Group 00 strains adapted to production in the northern fringe of the present area of soybean production. Uniform Tests 0 through IV include later maturing strains adapted to locations progressively further south in the North Central States and areas of similar latitude. Each year new selections are added …

Medical Aid In Dying, Semoon Chang

KAUPA Letters

No abstract provided.

The State Of The Art Of Telecommunications Service Management, Young B. Choi

KAUPA Letters

No abstract provided.

What Is The Future Of The Korean Peninsula?, Yeomin Yoon

KAUPA Letters

No abstract provided.