Digital Commons Network^™

Investigation Of Lithium-Ion Battery Electrode Fabrication Through A Predictive Particle-Scale Model Validated By Experiments, Mojdeh Nikpour

Theses and Dissertations

Next-generation batteries with improved microstructure and performance are on their way to meet the market demands for high-energy and power storage systems. Among different types of batteries, Li-ion batteries remain the best choice for their high energy density and long lifetime. There is a constant but slow improvement in Li-ion batteries by developing new materials and fabrication techniques. However, further improvements are still needed to meet government and industry goals for cost, cycling performance, and cell lifetime. A fundamental understanding of particle-level interactions can shed light on designing new porous electrodes for high-performance batteries. This is a complex problem because …

Predicting Drug-Induced Liver Injury With Artificial Intelligence, Ting Li

Theses and Dissertations

Drug-induced liver injury (DILI) is an undesirable side effect to the liver caused by the common use of drugs, which is of great concern to the patients, physicians, the pharmaceutical industry, and government regulators. The current animal testing models do not present reliable results on the human DILI risk prediction during the preclinical phase. Therefore, there is an urgent need to find alternative methods to improve the human DILI risk prediction during the early stage of development. Utilizing the accumulated high-throughput transcriptomics profiles from L1000, we constructed an 8-layer deep neural network for human DILI prediction based on the largest …

Detecting Supraglacial Debris Thickness With Gpr Under Suboptimal Conditions, Alexandra Giese, Steven Arcone, Robert Hawley, Gabriel Lewis, Patrick Wagnon

Dartmouth Scholarship

The thickness of a supraglacial layer is critical to the magnitude and time frame of glacier melt. Field-based, short pulse, ground-penetrating radar (GPR) has successfully measured debris thickness during a glacier's melt season, when there is a strong return from the ice-debris interface, but profiling with GPR in the absence of a highly reflective ice interface has not been explored. We investigated the performance of 960 MHz signals over 2 km of transects on Changri Nup Glacier, Nepal, during the post-monsoon. We also performed laboratory experiments to interpret the field data and investigate electromagnetic wave propagation into dry rocky debris. …

The Impact Of Critical Incidents On Nurses And Midwives: A Systematic Review, Melanie Buhlmann, Beverley Ewens, Amineh Rashidi

Research outputs 2014 to 2021

Aims: To synthesise the existing literature, which focuses on the impact of critical incidents on nurses and midwives, and to explore their experiences related to the support they received in the current healthcare environment to move on from the event.

Design: Systematic review and qualitative synthesis.

Data sources: The electronic databases CINAHL, MEDLINE, PsycINFO, PubMed, Embase and Nursing and Allied Health (ProQuest) were systematically searched from 2013–2018, and core authors and journals identified in the literature were manually investigated.

Review methods: Qualitative studies of all research design types written in English were included according to the PRISMA reporting guidelines. The …

Characterizing Primary Care For Patients With Major Depressive Disorder Using Electronic Health Records Of A Us-Based Healthcare Provider, Sharon L. Larson, Andrei Nemoianu, Debra F Lawrence, Melissa A Troup, Michael R Gionfriddo, Bobak Pousti, Haiyan Sun, Faisal Riaz, Eric S Wagner, Lambros Chrones, Maelys Touya

College of Population Health Faculty Papers

Background: Major depressive disorder (MDD) is predominantly managed in primary care. However, primary care providers (PCPs) may not consistently follow evidence-based treatment algorithms, leading to variable patient management that can impact outcomes.

Methods: We retrospectively analyzed adult patients with MDD seen at Geisinger, an integrated health system. Utilizing electronic health record (EHR) data, we classified patients as having MDD based on International Classification of Disease (ICD)-9/10 codes or a Patient Health Questionnaire (PHQ)-9 score ≥5. Outcomes assessed included time to first visit with a PCP or behavioral health specialist following diagnosis, antidepressant medication switching, persistence, healthcare resource utilization (HRU), and …

Mosque Architecture And Identity: A Study Of The Autochthonous Mosque In China, Yutong Ma

Graduate School of Architecture & Urban Design Theses & Dissertations

This thesis argues that an autochthonous mosque architecture exists in China, and this historical type adequately serves as a reference for contemporary mosque building in southeastern China in light of how it responded to the Chinese cultural and urban contexts. Many Hui Muslims and architects in this region refuse to consider historical mosque architecture built in traditional Chinese architectural style as their cultural references in constructing new mosques, as they believe that the traditional Chinese architectural language is insufficient to express their identity as Muslims. Instead, they prefer a collection of symbolic architectural elements to be used in mosque architecture …

Responses To Environmental Change, Lisa Reyes Mason, Susan P. Kemp, Lawrence A. Palinkas, Amy Krings

Social Work: School of Social Work Faculty Publications and Other Works

Communities worldwide are facing environmental crises such as air pollution, water shortages, climate change, and other forms of environmental change and degradation. While technical solutions for environmental change are essential, so too are solutions that consider social acceptability, value cultural relevance, and prioritize equity and social justice. Social work has a critical and urgent role in creating and implementing macrolevel social responses to environmental change. The key concepts of environmental change, environmental and ecological justice, social vulnerability, and social responses are discussed. A description of the roles and skills unique to macro social workers for this effort is given, followed …

A Portrait Of Postsecondary Stem Teaching: Examining The Roles Of Organizational Climate And Professional Identity, Sule Aksoy

Dissertations - ALL

Many empirical studies on the factors associated with the use of evidence-based instructional practices have examined the individual and contextual characteristics. However, little attention has been afforded to the role of context and practice on teacher identity. This dissertation consists of three-article style papers that examine the relationship between contextual factors, teacher identity, and instructional practices to fill this gap in the literature. Chapter 1 provides a deep understanding of organizational climate in STEM departments concerning teaching practices. Significant differences in organizational factors such as leadership, resources, and respect for teaching were found between graduate instructors and the faculty. Similarly, …

Exploration Of Carbon-Oxygen And Carbon-Nitrogen Bond Formation Utilizing Trichloroacetimidates And Investigations Of New Reactions Mediated By Oxoammonium Salts, Rowan Meador

Dissertations - ALL

Mono-O-alkylated 1,1′-bi-2-naphthols (BINOLs) are often used as the source of chirality for catalysts or ligand systems that are employed in asymmetric organic transformations. However, these BINOLs can be hard to synthesize. The O-alkylation of BINOL can be accomplished with primary and secondary alkyl halides or under Mitsunobu conditions, the yields of these alkylations with tertiary halides or alcohols are very low. A new protocol was developed utilizing trichloroacetamide electrophiles to install bulky groups onto one of the phenolic oxygens. Trichloroacetimidates are also shown to be useful reactions for the synthesis of esters. These reagents proceeded through a symbiotic activation pathway. …

Policy And Polity: Space, Boundaries, And Governance In Early Modern London, 1580-1640, Michael Britton

Dissertations - ALL

The kingdom's principal city for law, governance, trade, and consumption, early modern London experienced a period of rapid growth and sprawl from the mid-sixteenth century. This nurtured more dense and frequent mobility and produced a dynamic, kinetic city. For civic authorities, however, boundaries took on greater urgence. Drawing on theories and principles of border studies, this dissertation treats the city's boundaries as processes forged and transformed by engagement, by the interplay between popular activity, political programs, and perceptions of space and authority. Policy and Polity, Space, Boundaries, and Governance in Early Modern London, 1580-1640 examines bordering at London Bridge, the …

Adsorption Of Organic Iodides On Reduced Silver Functionalized Silica Aerogel, Siqi Tang

Dissertations - ALL

In the nuclear waste reprocessing, radioactive iodine is released in both organic and inorganic forms into off-gas streams. Due to its properties of long half-life and accumulation in human bodies, the radioactive iodine is required to be removed by the Environmental Protection Agency (EPA) and Nuclear Regulatory Commission (NRC). In this presented work, the removal of organic iodides is studied particularly. Unlike that of inorganic iodine, the organic iodides were not well studied because of the low concentrations and the corresponding technical difficulties. Most of the studies on the organic iodides are semi-quantified, focusing on the performances of the adsorption …

A Graduatte Level Immersive-Simulattion Program For Teaching And Assessing Fundamental Skills In Entry Level Clinical Perfusionists., Bruce Searles

Dissertations - ALL

Background: The clinical perfusionist is a member of the open-heart-surgery team and responsible for operating the life support equipment that replaces the function of the patient's heart and lungs and arrests and restarts the patient's heart in the course of a Cardiopulmonary Bypass (CPB) procedure. In the perfusionists scope of practice, the consequence of unskilled actions, inaccurate understanding or delayed decision making may result in significant patient morbidity or even death. Historically, perfusion students have learned and practiced their skills within a clinical preceptorship program in which an experienced clinician allows the novice student to operate the life support equipment …

Antimicrobial Susceptibility Of P. Aeruginosa Clinical Isolates, Tian Gao

Theses - ALL

Long-term infection caused by P. aeruginosa poses a major threat to personal and public health, and causes billions of dollars in medical expenses. To develop more effective controls, it is important to accurately evaluate antibiotic susceptibility of clinical isolates and understand how susceptibility changes during the course of infection. Conventional drug susceptibility tests using nutrient-rich media have been questioned regarding their relevance due to the difference between the model in vivo test conditions and the environment in the patients. Here, we report that 27 clinical strains of P. aeruginosa isolated from cystic fibrosis patients showed higher drug resistance in Artificial …

2012 December University Of Memphis Commencement Program

Commencements

Program for the Fall convocation of the 101st commencement of the University of Memphis at Memphis, Tennessee, held at the FedEx Forum on December 16, 2012.

Developing An Air Pollutant Emissions Database For Global Economic Analysis, Maksym Chepeliev

Department of Agricultural Economics Faculty Publications

According to the Global Burden of Disease study (Cohen et al., 2017), in 2015 ambient air pollutant emissions caused 4.2 million deaths and a loss of 103.1 million disability-adjusted life-years, making it the fifth-ranked global risk factor. In terms of the welfare costs of mortality and illnesses associated with outdoor air pollutant emissions, global estimates for 2015 range between $2.7-3.2 trillion (Coady et al., 2015; OECD, 2016). Still, while greenhouse gas emissions are usually well represented in many global economic databases and models, air pollutant emission accounts in most cases are not included. In particular, this is the case for …

Realistic Additions To Matlab Simulation Of Active Particles In An Acoustic Field, Emily Ma

Mechanical Engineering and Materials Science Independent Study

Acoustic microfluidics provides a contact-free method of manipulating active particles; however, versatile and quick performance quantification of these methods is needed to further apply acoustofluidic techniques in broader settings. Motile Chlamydomonas reinhardtii algae cells continuously swim and redistribute as they are subject to an acoustic field. For performance quantification, this eliminates the tedious procedure of resetting the experiment after each trial, which is necessary when using passive particles as probes. Thus, this method of calibration using active particles is more efficient than using passive particles. Utilizing an accurate simulation of physical active particle experiments is helpful in quickly predicting how …

Bactericidal Effects And Stability Of Ll-37 And Cama In The Presence Of Human Lung Epithelial Cells, Regina Geitani, Carole Ayoub Moubareck, Floriane Costes, Léa Marti, Gabrielle Dupuis, Dolla Karam Sarkis, Lhousseine Touqui

All Works

Cationic antimicrobial peptides (CAMPs) are important actors in host innate immunity and represent a promising alternative to combat antibiotic resistance. Here, the bactericidal activity of two CAMPs (LL-37, and CAMA) was evaluated against Pseudomonas aeruginosa (PA) in the presence of IB3-1 cells, a cell line derived from patients with cystic fibrosis. The two CAMPs exerted different effects on PA survival depending on the timing of their administration. We observed a greater bactericidal effect when IB3-1 cells were pretreated with sub-minimum bactericidal concentrations (Sub-MBCs) of the CAMPs prior to infection. These findings suggest that CAMPs induce the production of factors by …

Impact Of Medical Blog Reading And Information Presentation On Readers' Preventative Health Intentions: Mixed Methods, Multistudy Investigation, Kimberly A. Taylor Dnp, Rn, Nea-Bc, Cnor, William F. Humphrey

Publications

Background:

Medical blogs have become valuable information sources for patients and caregivers. Most research has focused on patients’ creation of blogs as therapy. But we know less about how these blogs affect their readers and what format of information influences readers to take preventative health actions.

Objective:

This study aimed to identify how reading patient medical blogs influences readers’ perceived health risk and their intentions to engage in preventative health actions. Further, we aimed to examine the format of the medical blog and the reader’s response.

Methods:

We surveyed 99 university participants and a general-population, online panel of 167 participants. …

Exploring The Therapeutic Effect Of Children's Picture Books, Yunfan Chen

Theses - ALL

This thesis discusses the phenomenon of left-behind children in China amid the country's urbanization, revealing the psychological state of these children in the countryside.

In this thesis, some psychological research sources have proven how picture books relieve children's emotions and attain therapeutic effects on children's psychology. Then, this thesis analyzes two examples of children's books depicting how picture books help children to manage their negative feelings and having a therapeutic effect on the child.

This thesis claims that bibliotherapy through children's independent reading of books can effectively alleviate left-behind children's negative emotions.

Sexual Dysfunction In Schizophrenia: A Narrative Review Of The Mechanisms And Clinical Considerations, Amber N. Edinoff, Catherine A. Nix, Juliana M. Fort, Jeanna Kimble, Ryan Guedry, George Thomas, Elyse M. Cornett, Adam Kaye, Alan D. Kaye

Pacific Faculty Work

Psychiatric disorders, in general, have a high prevalence of sexual problems, whether from the psychopathology of the disorder itself, pre-existing or co-morbid sexual disorder or from side effects of the treatment for mental disorders. Many patients report an already existing sexual dysfunction at the onset of diagnosis. The risk association for developing sexual dysfunction in patients with schizophrenia includes antipsychotic use and resulting hyperprolactinemia, age, gender, and disease severity. Medication side effects lead to nonadherence, and relapses lead to structural changes in the brain, treatment resistance, and worsening of symptoms. Findings in certain studies propose serum prolactin and thyroid-stimulating hormone …

Fine Scales, Broad Consequences: Drivers And Effects Of Microclimatic Variation In Great Smoky Mountains National Park, Jordan Rebecca Stark

Theses - ALL

Climate is highly variable at scales that are not captured by most weather and climate models due to local effects of topography and living systems. This variation in microclimate has been noted for many decades but has been difficult to incorporate into quantitative understanding of ecological systems and processes due to the large amount of data and complex models required to adequately describe fine-scale patterns across complex landscapes. In recent years, models of thermal microclimate variation have been developed using low-cost temperature sensors, but few of these models have been used to predict the effects of microclimatic variation on ecological …

Aging Study Of Silver-Exchanged Mordenite And Silver-Functionalized Silica Aerogel In Dry Air, Humid Air, No And No2, Seungrag Choi

Dissertations - ALL

Iodine-129 (129I) is one of the volatile radioactive species in the off-gas streams generated from the spent nuclear fuel reprocessing system, and it is essential to remove 129I vapor because 129I has a long half-life (1.6 x 107 years) and can be fatal to the human body if released to the environment. Radioactive iodine vapor can be effectively captured by silver containing adsorbents such as silver exchanged mordenite (Ag0Z) and silver functionalized silica aerogel (Ag0-aerogel) used in this study. However, the aging impact of off-gas streams on the adsorbents is one of major issues in the removal of radioactive iodine …

Rational Design Of Supported Metal Catalysts For Carbonyl Reduction During Biomass Upgrading, Xin Gao

Dissertations - ALL

Ketone hydrogenation:A model system of carbonyl (ketone) hydrogenation, acetone hydrogenation over supported Pt catalysts in the gas-phase fixed bed reactor was investigated to understand both the mechanism and rate controlling steps in a fundamental level. The experiments and outcomes include the detailed macro- and micro-kinetic analysis of hydrogenation of acetone. The apparent reaction orders of hydrogen and acetone, apparent activation energies, and observed kinetic isotope effects over a large range of temperatures and concentrations (compound partial pressures) are reported in this document. Generally speaking, the ketone hydrogenation over metal surfaces in vapor phase comply with the mechanism that hydrogen atoms …

Intralocus Sexual Conflict Over Optimal Nutrient Intake And The Evolution Of Sex Differences In Life Span And Reproduction, Michael Hawkes, Sarah M. Lane, Scott K. Sakaluk, John Hunt, Clarissa M. House, Kim Jensen, James Rapkin

Faculty Publications – Biological Sciences

1. Despite widespread variation in life span across species, three clear patterns exist: sex differences in life span are ubiquitous, life span is commonly traded against reproduction, and nutrition has a major influence on these traits and how they trade-off. One process that potentially unites these patterns is intralocus sexual conflict over the optimal intake of nutrients for life span and reproduction. If nutrient intake has sex-specific effects on life span and reproduction but nutrient choice is genetically linked across the sexes, intralocus sexual conflict will occur and may prevent one or both sexes from feeding to their nutritional optima.
2. Here …

Notes From The Editorial Office (Volume 36, Issue 2), John J. Green

Journal of Rural Social Sciences

With volume 36, issue 2 of the Journal of Rural Social Sciences (JRSS), we are pleased to share two recent Presidential Addresses from the Southern Rural Sociological Association (SRSA), originally presented at SRSA annual conferences held in 2020 and 2021. Dr. Jin Young Choi (Sam Houston State University) spoke at the February 2020 conference held in Lexington, Kentucky, and Dr. David Nii O. Tackie (Tuskegee University) presented during the February 2021 virtual conference.

Platelet Micrornas Inhibit Primary Tumor Growth Via Broad Modulation Of Tumor Cell Mrna Expression In Ectopic Pancreatic Cancer In Mice, Jeremy G.T. Wurtzel, Sophia Lazar, Sonali Sikder, Kathy Q Cai, Igor Astsaturov, Andrew S Weyrich, Jesse W Rowley, Lawrence E. Goldfinger

Department of Medicine Faculty Papers

We investigated the contributions of platelet microRNAs (miRNAs) to the rate of growth and regulation of gene expression in primary ectopic tumors using mouse models. We previously identified an inhibitory role for platelets in solid tumor growth, mediated by tumor infiltration of platelet microvesicles (microparticles) which are enriched in platelet-derived miRNAs. To investigate the specific roles of platelet miRNAs in tumor growth models, we implanted pancreatic ductal adenocarcinoma cells as a bolus into mice with megakaryocyte-/platelet-specific depletion of mature miRNAs. We observed an ~50% increase in the rate of growth of ectopic primary tumors in these mice compared to controls …

"We, As Parents, Do Have A Voice": Learning From Community-Based Programs Effectively Engaging Parents In Urban Communities, Elizabeth Gil, Ashley Johnson

GSE Faculty Publications

Utilizing Yosso’s community cultural wealth framework as a theoretical lens, we sought to examine how nontraditional, community-based family engagement programs impacted adult family members’ thoughts and actions about engagement with their children's schools. The study drew primarily from the interviews, observations, and document analysis of two nontraditional family engagement programs in urban communities. Findings indicate that program approaches built upon and extended families’ social and navigational capitals. Educational leaders can more meaningfully engage urban families by learning from and incorporating practices implemented by the programs we examine and discuss in this article.

Instructional Scaffolding In Internships: Supporting Future Professionals In Family Science, Katy Gregg, Meghan K. Dove, Nikki Digregorio

Human Ecology: Faculty Publications

Internships are known for being a valuable, albeit time consuming, opportunity for students, supervisors, and faculty in many fields. As undergraduate programs consider their current and future internship programs, we suggest the processes an intern takes to secure and complete an internship are key to furthering their learning and increasing their career marketability. In this article, we use scaffolding and self-efficacy theories as the foundation to developing an intentional internship program in the family science field. We share the steps faculty take to prepare students for the internship, use graduated guidance to support student learning, and to assess learning during …

Atrial Fibrillation In Middle Eastern Arabs And South Asians: A Scoping Review, Amar M. Salam, Rasha Kaddoura, Vehid Salih, Sanjay Asopa

Peninsula Dental School

No abstract provided.

Control Flow Integrity For Real-Time Embedded Systems, Yuqian Huo

McKelvey School of Engineering Graduate Student Theses & Dissertations

Devices built on embedded systems are widely used in our daily lives. Nowadays, firmware typically uses C and C++ for efficiency and durability. However, those languages are unsafe which can lead to many software and system security issues. Attackers can easily corrupt a system by issuing various memory corruption attacks on a vulnerable program. Control-flow integrity is one of the most prevalent mechanisms used to protect against memory corruption. Most research papers and prototypes focus on using CFI on high-performance chips such as Intel and ARM Cortex-A. However, many embedded systems targeting time critical services are built on resource constrained …