Digital Commons Network^™

Covid-19: Does The Timing Of Intubation Affect Overall Outcomes, Jennifer Burvee

Nursing Masters Papers

COVID-19 also known as coronavirus disease of 2019 is a viral illness caused by novel coronavirus SARS-CoV2 that was discovered in December 2019 in Wuhan, China. To date, there have been over 250 million cases worldwide. The severity of COVID-19 ranges from mild symptoms to critical illness warranting hospitalization within an intensive care unit to death. Current treatment modalities include supportive cares, monoclonal antibodies, interleukin inhibitors, convalescent plasma, therapeutic anticoagulants, anti-inflammatory medications and/or corticosteroids. A common complication due to COVID-19 is acute respiratory failure resulting in pulmonary insult which start as cough but progress to the need for supplemental oxygen …

3d Bio-Printability Of Hybrid Pre-Crosslinked Hydrogels, Cartwright Nelson, Slesha Tuladhar, Loren Launen, Ahasan Habib

New Hampshire EPSCoR

Maintaining shape fidelity of 3D bio-printed scaffolds with soft biomaterials is an ongoing challenge. Here, a rheological investigation focusing on identifying useful physical and mechanical properties directly related to the geometric fidelity of 3D bio-printed scaffolds is presented. To ensure during- and post-printing shape fidelity of the scaffolds, various percentages of Carboxymethyl Cellulose (CMC) (viscosity enhancer) and different calcium salts (CaCl2 and CaSO4, physical cross-linkers) were mixed into alginate before extrusion to realize shape fidelity. The overall solid content of Alginate-Carboxymethyl Cellulose (CMC) was limited to 6%. A set of rheological tests, e.g., flow curves, amplitude tests, and three interval …

Comparison Of Major Cloud Providers, Justin Berman

Other Student Works

This paper will compare the following major cloud providers: Microsoft Azure, Amazon AWS, Google Cloud, and IBM Cloud. An introduction to the companies and their history, fundamentals and services, strengths and weaknesses, costs, and their security will be discussed throughout this writing.

Origins Of Heavy Metals, Brooks Payette

UNH Today Archive

No abstract provided.

Juvenile Alewife (Alosa Pseudoharengus) Feeding Habits, Movement And Residency In A Northern Temperate Estuary, Amy E. Webb

All Student Scholarship

River herring is a term applied collectively to both alewife, Alosa pseudoharengus, and blueback herring, A. aestivalis, anadromous fish that spend most of their life in the ocean and migrate upriver to freshwater to spawn each spring (NEFSC 2006). Juveniles spend their first summer in freshwater and are thought to migrate to the ocean in fall, where they remain until they are sexually mature and ready to spawn (three to five years; ASMFC 2012).

$2.1 Million Grant Seeks To Identify Potential Therapeutic Strategy For Alzheimer's Disease, Staff

Browse All News

No abstract provided.

Il-4i1 Regulation Of Immune Protection During Mycobacterium Tuberculosis Infection., Lerato Hlaka, Mumin Ozturk, Julius E Chia, Shelby-Sara Jones, Shandre Pillay, Sibongiseni K L Poswayo, Thabo Mpotje, Justin K Nono, Simphiwe R N Simelane, Suraj P Parihar, Sugata Roy, Harukazu Suzuki, Frank Brombacher, Reto Guler

Faculty Research 2021

BACKGROUND: Interleukin 4 (IL-4i1)-induced gene 1 encodes L-phenylalanine oxidase that catabolizes phenylalanine into phenylpyruvate. IL-4i1 is mainly expressed by antigen-presenting cells (APCs), inhibits T-cell proliferation, regulates B-cell activation, modulates T cell responses, and drives macrophage polarization, but its role in bacterial infections is understudied.

METHODS: We evaluated IL-4i1 deletion in macrophages and mice on infection with virulent H37Rv and W-Beijing lineage hypervirulent HN878 Mycobacterium tuberculosis (Mtb) strains. The bacterial growth and proinflammatory responses were measured in vitro and in vivo. Histopathological analysis, lung immune cell recruitment, and macrophage activation were assessed at the early and chronic stages of Mtb infection. …

Deep Learning Approach To Improved Image Quality For Medical Diagnostics, Olivia Loesch, Katie Leyba, Halyley Chan, Craig Goergen

Discovery Undergraduate Interdisciplinary Research Internship

The United Nation’s health-related Sustainable Development Goals are difficult to achieve in low- and middle-income countries due to workforce shortages and inadequate health surveillance systems. However, with the growth of artificial intelligence (AI) and computer algorithms, it is possible to apply AI to healthcare technologies to improve progress towards these UN standards. This project aims at using and improving computer algorithms and deep learning to aid in the extraction of important structural and functional information from murine carotid artery ultrasound and photoacoustic images. First, we created a large database of simulated photoacoustic images to optimize the algorithms. These images were …

Exploring Differences Of Age And Gender On Perceived Experience Of Active Participation Cybersecurity Learning, James Lakko

Undergraduate Honors Theses

Many organizations including the United States government have identified a shortage of cybersecurity professionals in the workforce. This thesis explores the effectiveness of escape room/simulation based learning in an active participation and immersive education to motivate pursuing cybersecurity. A survey was administered to the participants of the 2021 BYU Cybersecurity Camp regarding their experience in the Interactive Cybersecurity Experience (ICE). The ICE is a simulator/escape room that challenges participants to complete a Star Trek themed mission by overcoming cybersecurity obstacles. The three demographics that were surveyed included a camp for educators, a camp for boys, and a camp for girls. …

Traffic Crash Prediction Using Machine Learning Models, Yifeng Chen

Dissertations and Theses

Traffic crashes account for most of casualties and injuries worldwide, and there has been growing concerns and studies regarding the contributing factors of traffic crashes. There are many factors causing or related to an occurrence of traffic crash, e.g., land use, traffic flow conditions, driver behavior and weather condition. This paper studied the spatial and temporal distribution of crashes on highway and developed real-time prediction models for crash occurrence. Traffic flow data, weather data, and crash data from multiple data sources were collected and processed to develop the model. Multiple machine learning models, such as SVM model and Decision Tree …

Multicenter Randomized Phase Ii Trial Of Atezolizumab With Or Without Cobimetinib In Biliary Tract Cancers, Mark Yarchoan, Andrea Wang-Gillam, Et Al

Open Access Publications

BACKGROUNDMEK inhibitors have limited activity in biliary tract cancers (BTCs) as monotherapy but are hypothesized to enhance responses to programmed death ligand 1 (PD-L1) inhibition.METHODSThis open-label phase II study randomized patients with BTC to atezolizumab (anti-PD-L1) as monotherapy or in combination with cobimetinib (MEK inhibitor). Eligible patients had unresectable BTC with 1 to 2 lines of prior therapy in the metastatic setting, measurable disease, and Eastern Cooperative Oncology Group (ECOG) performance status less than or equal to 1. The primary endpoint was progression-free survival (PFS).RESULTSSeventy-seven patients were randomized and received study therapy. The trial met its primary endpoint, with a …

Supplemental Specifications (700ss) Of The Standard Specifications For Road And Bridge Construction, January 1, 2021, Tennessee. Department Of Transportation.

TDOT Standard Specifications

No abstract provided.

High Performance Document Store Implementation In Rust, Ishaan Aggarwal

Master's Projects

Databases are a core part of any application which requires persistence of data. The performance of applications involving the use of database systems is directly proportional to how fast their database read-write operations are. The aim of this project was to build a high- performance document store which can support variety of applications which require data storage and retrieval of some kind. This document store can be used as an independently running backend service which can be utilized by search engines, applications which deal with keeping records, etc. We used Rust to make this document store which is fast, robust, …

Employee Churn Prediction Using Logistic Regression And Support Vector Machine, Rajendra Maharjan

Master's Projects

It is a challenge for Human Resource (HR) team to retain their existing employees than to hire a new one. For any company, losing their valuable employees is a loss in terms of time, money, productivity, and trust, etc. This loss could be possibly minimized if HR could beforehand find out their potential employees who are planning to quit their job hence, we investigated solving the employee churn problem through the machine learning perspective. We have designed machine learning models using supervised and classification-based algorithms like Logistic Regression and Support Vector Machine (SVM). The models are trained with the IBM …

Effect Of Biofertilizer In Organic And Conventional Systems On Growth, Yield And Baking Quality Of Hard Red Winter Wheat, Ammar Al-Zubade, Timothy D. Phillips, Mark A. Williams, Krista L. Jacobsen, David Van Sanford

Horticulture Faculty Publications

A two-year study (harvest years 2019 and 2020) was conducted to investigate the effect of a commercially available biofertilizer, in combination with variable nitrogen (N) rate, on bread baking quality and agronomic traits in hard winter wheat grown in conventional (CONV) and organic (ORG) farming systems in Kentucky, USA. The hard red winter wheat cultivar ‘Vision 45’ was used with three N rates (44, 89.6 and 134.5 kg/ha as Low, Med and High, respectively) and three biofertilizer spray regimes (no spray, one spray and two sprays). All traits measured were significantly affected by the agricultural production system (CONV or ORG) …

Not Again, Victor M. Perez Iii

Theses and Dissertations

Victor Perez explores personal narratives involving artifice, domesticity, and patriarchal harms through paintings which use a hybrid of digital and hand applied painting.

Always Wednesday, Danielle Roberts

Theses and Dissertations

Danielle Roberts’ work explores personal narratives. The spaces she paints radiate, simultaneously dark and luminescent. Resembling the kind of archetypes of place used in film her cinematic compositions invite the viewer into the frame. Her figures capture feelings of alienation illuminated by the unnatural existential glow of constructed contemporary light.

Open Pedagogy As A Tool For Facilitating The Design Of Learner Centered Open Educational Resources, Yang Wu, Matthew Boyer

OER & Beyond - Blog Archive

Open pedagogy, or Open Educational Practices, is a creative movement in education that combines constructivist principles of giving students creativity and self direction in learning, critical pedagogy and the creation of openly licensed online learning materials (DeRosa & Jhangiani, 2018, 10; Cronin & MacLaren, 2018, 136-137), is increasingly rising to the forefront of the Open Education movement. The potentials of open pedagogy in enhancing teaching, particularly in terms of fostering student engagement, creating opportunities for new forms of teaching that transcends the limits of copyright, the “surveillance” and “banking” models of education, as well as getting students to critically re …

Unh Receives $3.5 Million To Develop Innovative Stem Education Programs, Robbin Ray

Media Relations

No abstract provided.

Extending The Quality Of Secure Service Model To Multi-Hop Networks, Paul M. Simon, Scott R. Graham

Faculty Publications

Rarely are communications networks point-to-point. In most cases, transceiver relay stations exist between transmitter and receiver end-points. These relay stations, while essential for controlling cost and adding flexibility to network architectures, reduce the overall security of the respective network. In an effort to quantify that reduction, we extend the Quality of Secure Service (QoSS) model to these complex networks, specifically multi-hop networks. In this approach, the quantification of security is based upon probabilities that adversarial listeners and disruptors gain access to or manipulate transmitted data on one or more of these multi-hop channels. Message fragmentation and duplication across available channels …

Characterization And Proteolytic Maturation Of Head Proteins In A Giant Salmonella Virus, Aaron Scheuch

Theses

Giant phages are of interest for biocontrol of pathogenic bacteria, however, there is limited knowledge about their biology. We study the Salmonella phage SPN3US to better understand virion structure and function. SPN3US has a contractile tail and a large T=27 icosahedral capsid that contains its 240-kb genome. Previous analyses showed the SPN3US virion is highly unusual because it contains >80 different proteins, a number that is highly unusual for a tailed phage. In addition, there is a mass (>40 MDa) of proteins ("ejection proteins") within the head that enter the Salmonella cell, possibly with roles in host takeover at …

Esaal (Smart Delivery System In Dubai), Banout Alketbi

Theses

Delivery sector has been facing many issues lately due to covid 19 pandemic mainly delivering items and packages late and some of them being in bad condition. The new smart delivery system ( will help in making the delivery system in Dubai more sustainable and at the same time more accurately functioning The proposed system will achieve that by running on their own tracks that are especially made for them to deliver Furthermore, the new designed system will be running and functioning depe nding on solar energy. These routes will be designed to have way to all of the areas …

Calculating Common Vulnerability Scoring System’S Environmental Metrics Using Context-Aware Network Graphs, Christopher Thomas Enoch

Theses

Software vulnerabilities have significant costs associated with them. To aid in the prioritization of vulnerabilities, analysts often utilize Common Vulnerability Scoring System’s Base severity scores. However, the Base scores provided from the National Vulnerability Database are subjective and may incorrectly convey the severity of the vulnerability in an organization's network. This thesis proposes a method to statically analyze context-aware network graphs to increase accuracy of CVSS severity scores. Through experimentation of the proposed methodology, it is determined that context-aware network graphs can capture the required metrics to generate modified severity scores. The proposed approach has some accuracy to it, but …

Beach Hazards: Riu Funana, Cape Verde, C Stokes, G Masselink, T Scott, L Brodie

School of Biological and Marine Sciences

No abstract provided.

Pay Inequality And Gender Pay Gap, Chris Constantopoulos

Student Theses and Dissertations

The topic of this thesis paper is pay inequality and gender pay gap, specifically within the United States while occasionally comparing Europe and other parts of the world. The research questions that are brought up while starting this thesis process were how the topic started and developed with the last 10 years. Plus, the potential strides to eliminate the thesis topics issues within the United States. The method of analysis for this thesis paper includes an integrative desktop literature review while analyzing various online and prior academic research articles. The result of studying the numerous amounts of research helped gather …

From Inspiration To Actualization: Designing An Mba That Can Deliver The Goods, Rodolfo P. Ang

Journal of Management for Global Sustainability

This invited essay continues the conversation on the International Association of Jesuit Universities’ (IAJU) white paper entitled “An Inspirational Paradigm for Jesuit Business Education.” Mr. Rodolfo P. Ang, one of the members of the Task Force that developed the white paper, talks about his experience of leading the Ateneo de Manila University Graduate School of Business toward the actualization of the paradigm.

Mixture Design Response Surface Methodology Analysis Of Seven Natural Bioactive Compounds To Treat Prostate Cancer, Ian Geddes Berlin

Theses and Dissertations

Natural bioactive compounds have drawn the interest of many researchers worldwide in their effort to find novel treatments, including prostate cancer (PC) treatment which is estimated to be 13.1% of all new cancer cases in the U.S. in 2021. Many of these bioactive compounds have been identified from treatments in traditional Chinese medicine (TCM), that often have multiple bioactive compounds present. However, in vitro studies frequently focus on the compounds in isolation, or in simple combinations of two compounds. We used mixture design response surface methodology (MDRSM) to assess changes in PC cell viability after 48 hours of treatment to …

A Novel Approach For Microscale Dry Contact Stiction And Friction Assessment: Experimentation And Analysis, Bin Zhang, Reza Namakian, Xiaoman Zhang, W. J. Meng, Jennifer Hay, Kurt Johanns

Faculty Publications

Accurate and quantitative evaluation of friction is of fundamental interest for materials science and manufacturing. Driven by the trend towards miniaturization, micro metal forming techniques with characteristic forming dimensions approaching a few microns have developed rapidly over the past two decades. In contrast, the assessment of microscale friction is lagging. Here, we present a novel test, compression molding and demolding test (CMDT), to assess stiction and friction at the microscale. CMDT was conducted via in-situ instrumented molding and demolding of an Al specimen with cylindrical tool steel and Ti alloy punches. High-rate data acquisition enabled direct measurements, for the first …

Phase Stability Of Novel Hfnbtativzr Refractory High Entropy Alloy Under Ion Irradiation, Jianren Zhou, Mark Kirk, Pete Baldo, Shengmin Guo, Fengyuan Lu

Faculty Publications

HfNbTaTiVZr refractory high entropy alloy (RHEA) fabricated by arc melting shows the single-phase body-centered cubic (BCC) structure. Radiation-induced amorphization (RIA) is observed at 2 displacements per atom (dpa) at 298 K while the specimen remains its crystal structure at 423 K. The critical amorphization temperature (Tc) is likely within 298–423 K. RIA is mainly attributed to the accumulation of Frenkel pairs caused by elastic collisions under ion irradiation and the large atomic size mismatch in the studied RHEA facilitates the amorphization process. RIA of RHEA is for the first time reported and the finding challenges the current understanding of phase …

Study Of How Cancers Spread Promises Treatment Options, Shea Stewart

University of Mississippi News

American Cancer Society funds UM professor's breast cancer research