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2021

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Transcriptomic Analysis Of Young Regenerating Magnocellular Neurons (Mcns) Vs Mature Non- Regenerating Mcns, Malak Alzidaneen Jan 2021

Transcriptomic Analysis Of Young Regenerating Magnocellular Neurons (Mcns) Vs Mature Non- Regenerating Mcns, Malak Alzidaneen

Theses and Dissertations

Mature mammalian CNS neurons do not regenerate or recover following injuries. Different transcription factors have been linked to axonal growth and survival, and regulation changes in these transcription factors will affect the expression levels of genes involved in axonal regeneration. A robust collateral sprouting response within the distant terminal field of magnocellular neurons, the neurohypophysis, arising from the contralateral non-injured supraoptic neurons have been shown in response to unilateral denervation of MCNs tracts. This response peaked at age 35 days then it was followed by a complete loss of the regenerative capacity between 35 days and 125 days of age. …


Fulfilling The Purpose Of Education: Voices Of North Dakota Graduates Pertaining To Curriculum And Graduation Requirements, Sarah Jean Ricks Jan 2021

Fulfilling The Purpose Of Education: Voices Of North Dakota Graduates Pertaining To Curriculum And Graduation Requirements, Sarah Jean Ricks

Theses and Dissertations

The purpose of this dissertation was twofold: to determine how graduates of North Dakota high schools perceived their educational experiences in relation to preparing them for their adult lives, and to determine how curriculum and graduation requirements at the time of this study in North Dakota Century Code (NDCC) 15.1-21, titled “Curriculum and Testing,” fulfilled the purpose of education in North Dakota. This study used a mixed-methods research design and includes a literature review and an online survey of 81 North Dakota high school graduates in the Dickinson area regarding the readiness of students who have graduated from North Dakota …


An Assessment Of Remotely Piloted Aircraft Training Methods And Measures, Zachary Waller Jan 2021

An Assessment Of Remotely Piloted Aircraft Training Methods And Measures, Zachary Waller

Theses and Dissertations

The collegiate aviation programs of higher education are seeking to adapt their capabilities and expertise toward educating a generation of airmen who will operate Remotely Piloted Aircraft (RPA). The collection of studies presented in this dissertation address this interest as higher education programs investigate the value of modalities and pedagogies, tune the application of instructional aids, and assess novel measurements for how students interact with their training. Three studies were completed in building this program of research. Study I, Waller et al. (2016), was published in a peer-reviewed journal and is adapted for reprint with permission. Study I established the …


Glutathione S-Transferase Pi-1 In Pancreatic Cancer Pathogenesis: Mechanistic Insights Into Its Role In Oxidative Stress, Cell Signaling, And Metabolic Pathways, Rahul Singh Jan 2021

Glutathione S-Transferase Pi-1 In Pancreatic Cancer Pathogenesis: Mechanistic Insights Into Its Role In Oxidative Stress, Cell Signaling, And Metabolic Pathways, Rahul Singh

Cellular and Molecular Biology

Pancreatic ductal adenocarcinoma (PDAC) is currently the third leading cause of cancer-related deaths in the US. Although surgery remains the most effective treatment option, only a few PDACs are resectable at diagnosis. Further, only a few PDAC patients respond to conventional chemotherapy making long-term survival notably challenging. Therefore, the identification of novel therapeutic targets is needed to improve PDAC treatment efficacy. Here, we investigated the role of glutathione S-transferase pi-1 (GSTP1) in PDAC pathogenicity. We postulated that a higher expression of GSTP1 provides selective advantages to PDAC cells by scavenging excessive reactive oxygen species (ROS) and promoting survival. Using shRNAs, …


Neural Networks And Sensitivity Analysis For Detection And Interpretation Of Structural Damage, Dayakar Naik Lavadiya Jan 2021

Neural Networks And Sensitivity Analysis For Detection And Interpretation Of Structural Damage, Dayakar Naik Lavadiya

Civil and Environmental Engineering

Computer vision (CV)-based approaches have gained a lot of attention in recent years for objective identification of damages both at structural and material scales. In this dissertation, the metallurgical phases and the two important modes of damage in structural steel, namely fracture and corrosion, are considered. Use of CV techniques for metallurgical phase identification and fracture type identification in steel microstructure is minimal and rely on pixel intensity information. When distinct phases or fracture types possess similar pixel intensities, predictions may be erroneous. In this dissertation, various texture recognition algorithms based on an ensemble of machine learning algorithms are proposed …


Journalists' Framing Of Terrorist Attacks And Audience Reaction: A Longitudinal Case Study Of The Boston Globe, Seseer Prudence Mou-Danha Jan 2021

Journalists' Framing Of Terrorist Attacks And Audience Reaction: A Longitudinal Case Study Of The Boston Globe, Seseer Prudence Mou-Danha

Communication

This study aimed to elaborate on the presentation of news about the Boston Marathon bombing on The Boston Globe’s Facebook page and people’s reaction to it. A social crisis such as this invites people’s attention to online news sources for seeking details. Reports presented by journalists can encourage, elicit fear, strengthen communities, and/or foster cooperation. As much as journalists try to be objective in their reporting, the ways in which they frame a story can influence audiences’ responses. The primary objective of this study was to understand how news frames align with audience response. The analyses of news posts and …


Building Plant 3d Genome Computing Resources, Chanaka Sampath Cooray Bulathsinghalage Jan 2021

Building Plant 3d Genome Computing Resources, Chanaka Sampath Cooray Bulathsinghalage

Computer Science

Chromatin interactions play increasingly important roles in three-dimensional genome organization and long-range gene regulation. Analyzing the three-dimensional structure of the plants is currently a growing field and we noticed that there is lack of computing resources on chromatin interactions for the plants. So, we are introducing a database of statistically significant chromatin interactions processed using Hi-C experimental approach. The users can search in the database using a set of genes or regions for a selected plant organism through a web browser and it lists down all the statistically significant chromatin interactions involved those genes or regions with the confidence scores, …


Differences In Dui Punishments And Recidivism Between Transfers Among Municipal And District Court, Alexander Menke Jan 2021

Differences In Dui Punishments And Recidivism Between Transfers Among Municipal And District Court, Alexander Menke

Criminal Justice and Political Science

The relationship between court transfers and punishment differences, as well as changes in recidivism, have been seldomly researched. This paper adds to the body of research by comparing punishments from DUI cases heard in municipal court and DUI cases heard in district court. The differences in recidivism between the defendants whose cases were heard in municipal and district court are also compared. A systematic sample of DUI offenders from Fargo and West Fargo, North Dakota make up the experimental and control groups. The 511 non-transfer cases are analyzed against the 402 transfer cases using crosstabulations and logistic regression techniques. The …


The Cathedral Of Consciousness: The Liminal Dimension Of Dreams And Meditative Thinking, Justin Todd Jan 2021

The Cathedral Of Consciousness: The Liminal Dimension Of Dreams And Meditative Thinking, Justin Todd

Architecture Theses

This thesis explores how architecture can redefine the human relationship to consciousness and how we experience consciousness itself. Specifically, this project will address different ways to bring participants face to face with our growing disconnect between perceptual experience and what we call reality. In other words, the Cathedral of Consciousness is a place for meditative thinking, showing how our current culture is headed down a destructive path, discounting particular modalities of perceiving a highly externalized and vision dominated world. Our reductive school of thought has changed the way we think and act, especially in terms of dreams. We have become …


The Reversible Edge: Traces Of Alterity At The Site Of Loss, Hart Island, New York, Musab Ataelmanan Jan 2021

The Reversible Edge: Traces Of Alterity At The Site Of Loss, Hart Island, New York, Musab Ataelmanan

Architecture Theses

“We cannot overlook the way in which the Industrial Revolution and its technological consequences have transformed the experience of death in people’s lives.” As discussed by the German Philosopher Hans-Georg Gadamer, we stand at a point where the relevance of death in our lives has increasingly been excluded from the public realm, as cemeteries and monuments have been displaced from the centers of our cities. This “underrepresentation of death” has had a tremendous effect on the cathartic articulation of the public ritual and the deep human need to reconcile the ephemeral boundaries of life and death. Drawing upon the surrealistic …


Continuum, Joshua Trojan Jan 2021

Continuum, Joshua Trojan

Architecture Theses

As a contemporary society, we pursue sustainability to mitigate environmental unbalance. However, we rarely reflect on the temporal and cyclical nature of our existence, which exposes the premise of sustainability; continuance through mindfulness and stewardship. Like much of the world, cities such as San Francisco have evicted the dead from the city. The displacement of cemeteries from the urban fabric threatens to conceal our temporal nature, condemning us to mindlessly dwell in the present with little concern for the wellbeing of the future. This project seeks to reverse this trend by making room for a dynamic urban cemetery that reveals …


The Effect Of Property Tax Relief On K-12 Education Expenditures In North Dakota, Kole Allen Nichols Jan 2021

The Effect Of Property Tax Relief On K-12 Education Expenditures In North Dakota, Kole Allen Nichols

Agribusiness and Applied Economics

North Dakota implemented two pieces of legislation in 2009 and 2013 to reduce property tax burdens. These policies encouraged local school districts to lower their property-tax mill rates and provided intergovernmental grants to school districts to replace the missing revenue. In this study I examine the effect of this change in policy on total school district expenditures. I employ panel econometric methods to analyze the effect that these property tax relief interventions had on county education expenditures in North Dakota. Though there were mixed results for the effect of the 2009 legislation, this study finds that the property tax relief …


Marijuana Legalization Effect On Opioid Abuse: A Synthetic Control Approach, Elisha Kwaku Denkyirah Jan 2021

Marijuana Legalization Effect On Opioid Abuse: A Synthetic Control Approach, Elisha Kwaku Denkyirah

Agribusiness and Applied Economics

The opioid epidemic constitutes one of the worst drug crises in the history of U.S. State-level policies, in general, have done little to prevent prescription opioid abuse. A noteworthy exception to other clinical efforts to curb opioid abuse is marijuana. Despite preliminary evidence, many states are hesitant to introduce legislation to expand access to medicinal marijuana or liberalize laws on the recreational use of marijuana, fearing additional research is needed. Utilizing a synthetic control method and annual state-level data from 2006 to 2018, this study examines the effect of recreational marijuana legalization on opioid abuse. The findings strongly indicate marijuana …


Manufacturing Low-Density Particleboards From Wheat Straw And Distiller's Dried Grains With Solubles, Sagar Regmi Jan 2021

Manufacturing Low-Density Particleboards From Wheat Straw And Distiller's Dried Grains With Solubles, Sagar Regmi

Agribusiness and Biosystems Engineering

Agricultural byproducts like wheat straw and distillers dried grains with solubles (DDGS) have not found a good market in the wood composite industry. Utilizing DDGS for particleboard in addition to using it as feed will add economic value. This study investigated the potential of using DDGS and wheat straw at different proportions in low-density particleboard with phenol-formaldehyde binder. The effect of alkaline pretreatment of DDGS and wheat straw on the properties of board was also studied. Particleboards were tested for physical and mechanical properties, including density, water absorption, thickness swelling, flexural, internal bond, screw withdrawal, and hardness properties. Particleboards with …


The Influence Of Beef Carcass Weight On Troponin-T Degradation And Heat Shock Protein 70 In Two Different Muscles, Supriya Deb Nath Jan 2021

The Influence Of Beef Carcass Weight On Troponin-T Degradation And Heat Shock Protein 70 In Two Different Muscles, Supriya Deb Nath

Animal Sciences

This study was aimed to assess how carcass size affects protein degradation in postmortem muscle and subsequent impacts on meat quality. Beef carcasses were randomly selected at slaughter and classified as heavy (> 430.9 kg; n = 22), average (351.5 to 385.6 kg; n = 23), or light (< 317.5 kg; n = 20). Troponin-T (TnT) and heat shock protein 70 (HSP70) were analyzed for protein abundance on 3-day aged longissimus (LD) and semimembranosus (SM) muscles and 14-day aged LD muscle. TnT degradation in heavy carcasses was greater in the d-3 SM muscle and less in the d-14 LD muscle. Carcass size was positively correlated with the 30 kDa TnT band in d-3 SM. Therefore, carcass size influenced the TnT degradation but had no influence on HSP70 protein activity in either LD or SM.


Supplemental Leucine In Milk Replacer Fed To Neonatal Calves And Lambs: Effects On Growth, Development, And Metabolism, Jessica Nora Reiners Jan 2021

Supplemental Leucine In Milk Replacer Fed To Neonatal Calves And Lambs: Effects On Growth, Development, And Metabolism, Jessica Nora Reiners

Animal Sciences

Maximizing growth during the neonatal period in preruminants can enhance long-term growth and productivity, increasing producer profits and input efficiency. Meeting the requirements for growth can be achieved through feeding singular amino acids, specifically leucine, to enhance protein synthesis in muscle tissues. In order to evaluate the impact of supplemental leucine in milk replacer fed to neonatal preruminants, three experiments were designed. Experiment 1 examined short-term effects of supplemental leucine administration on calf and organ growth, nutrient digestibility and nitrogen retention, serum amino acid and metabolite profiles, and regulators of protein synthesis. Experiment 2 determined long-term effects of supplemental leucine …


Use Of Soybean Hulls In Drylot Cow-Calf Diets, Rebecca Lynn Moore Jan 2021

Use Of Soybean Hulls In Drylot Cow-Calf Diets, Rebecca Lynn Moore

Animal Sciences

One hundred and twenty-one Red Angus beef cows were used to evaluate the effects ofsoybean hull inclusion in drylot beef cow diets. Cows were stratified by age, body weight (BW),and body condition score (BCS), and randomly assigned to treatment (n = 4 pens per treatment).Treatments included a control diet (CON) and soybean hull diet (SBH). Beef cow BW, BCS,ultrasound backfat (BF) measurements, colostrum quality, and milk production were evaluated.Beef calf performance was evaluated based on birth weight, weaning weight, ADG, andultrasound measurements of BF, rump fat, and ribeye area at weaning. Dam BW, BCS, and BFmeasurements were not affected (P …


In-Silico Investigation Of Geological And Biological Materials By Molecular Dynamics Simulations, H M Nasrullah Faisal Jan 2021

In-Silico Investigation Of Geological And Biological Materials By Molecular Dynamics Simulations, H M Nasrullah Faisal

Materials and Nanotechnology

Molecular dynamics (MD) simulation is a computational technique that predicts the time-dependent behavior of a molecular system utilizing molecular mechanics. MD simulations are extensively employed in the scientific arena to investigate a wide range of material systems at the nanoscale (atoms and molecules), including organics, inorganics, polymer, composites, biomacromolecules, etc. This work investigates the properties of a range of geological (Green River oil shale and swelling clays) and biological materials (coronaviral proteins) at the molecular level using MD simulations. Oil shale, a sedimentary rock containing organic crude oil precursor named kerogen trapped in an inorganic mineral matrix, has long been …


What’S The Church’S Official Position On Official Positions?: Grappling With “Truth” And “Authority”, Trevan Hatch Jan 2021

What’S The Church’S Official Position On Official Positions?: Grappling With “Truth” And “Authority”, Trevan Hatch

Faculty Publications

In the previous essay, Dr. Rabbi Peter Haas considered how some of our Jewish friends have approached the issue of authority in their search for truth. During my engagement with such approaches as a student at Baltimore Hebrew University, Hebrew University of Jerusalem, and the Spertus Institute of Jewish Studies in Chicago, I have wondered how this approach might inform my own quest for truth within the context of my faith tradition. As a Latter-day Saint, what authorities should I consult? Where do I turn for truth? How can I know whether a certain claim is an “official position” of …


The Inkblot Re-Conceptualized: Developing An Implicit Situational Judgment Test Of Multiple Components Of Poor And Optimal Functioning, Roberta Linda Irvin Jan 2021

The Inkblot Re-Conceptualized: Developing An Implicit Situational Judgment Test Of Multiple Components Of Poor And Optimal Functioning, Roberta Linda Irvin

Psychology

Situation judgment tests (SJTs), which provide a balance between global personality measurement and context-specific social-cognitive processes, can be combined with implicit measurement approaches to limit some of the biases that are common in self-reports. Based on such considerations, the author developed an implicit SJT, called the Inkblot Scale, to investigate three components of optimal functioning – Happiness, Success, and Friendliness – that can be assessed from the same response set. Undergraduates completed the Inkblot Scale and various measures related to each component of optimal functioning (n = 184) before reporting their daily experiences and behaviors for two weeks (n = …


Fighting Tigers With A Stick: An Evaluation Of U.S. Army Recruitment, Training, And Their Combat Outcomes In The Korean War, Jonathan Banks Jan 2021

Fighting Tigers With A Stick: An Evaluation Of U.S. Army Recruitment, Training, And Their Combat Outcomes In The Korean War, Jonathan Banks

War, Diplomacy, and Society (MA) Theses

After the Korean War, most people regarded the performance of the U.S Army in that conflict as largely checkered. It had not once, but twice retreated disgracefully, losing to theoretically inferior third world armies. Its soldiers often performed poorly, not just in battle, but also prison camps. Many scholars, military commentators, and journalists have since tried to dissect the failures of the U.S. Army in Korea. Some have examined whether or not American GIs received proper combat training before and during the war. Indeed, problems existed with American infantry training before and during the early phases of the Korean War. …


Improving Disease Management In Field Pea And Durum Wheat In The Mondak Region, Taheni Gargouri-Jbir Jan 2021

Improving Disease Management In Field Pea And Durum Wheat In The Mondak Region, Taheni Gargouri-Jbir

Plant Pathology

Results from wilt pathogenicity and race evaluations for 25 North Dakota Fusarium oxysporum f.sp. pisi (Fop) isolates conducted in the greenhouse indicated all Fop races exist in North Dakota. Race 2 isolates were more frequently recovered from plants with root rot symptoms. Root rot assays also conducted in the greenhouse demonstrated that most Fop isolates were as aggressive as F. solani and F. avenaceum based on increased root disease severity. Results from field experiments conducted in 4 sites in the MonDak region between 2017 and 2019 evaluating the effect of three planting dates and six durum varieties with differing levels …


Total Quality Management In Higher Education: A Soft Factor Approach Based On Faculty Satisfaction, Samrat Singh Jan 2021

Total Quality Management In Higher Education: A Soft Factor Approach Based On Faculty Satisfaction, Samrat Singh

Industrial and Manufacturing Engineering

The literature review showed very few organization-wide Total Quality Management (TQM) implementations and mixed opinions regarding its compatibility in Higher Education Institutions (HEIs). Considering the human-centric nature of HEIs this study investigated the interrelationship between the Soft TQM Factors, Faculty Satisfaction, and Student Success. A survey was designed to assess respondents’ perceptions regarding the implementation of Soft TQM Factors and satisfaction among faculty. Analysis of the responses revealed a clear positive relationship between Soft TQM Factors and Faculty Satisfaction. Moreover, Faculty Satisfaction was found to be associated with one of the measures of Student Success, the Graduation Rate. Thus, this …


A Study Of Degradation Modeling And Lifetime Estimation Of Capacitors, Anunay Gupta Jan 2021

A Study Of Degradation Modeling And Lifetime Estimation Of Capacitors, Anunay Gupta

Industrial and Manufacturing Engineering

The degradation of capacitors under accelerated stress conditions occurs in a monotonic and non-linear fashion. Several efforts have been made to model the degradation behavior of capacitor considering either physics-of-failure models or statistical models and subsequently estimate its reliability and lifetime parameters. But most of these models fail to reflect the physical properties of the degradation path, which varies according to several intrinsic and extrinsic factors. These factors introduce random and temporal uncertainty among the population of capacitors. The Gamma stochastic process can model both type of uncertainties among the population of capacitors. In this thesis, we model the capacitor …


Connecting Us, Taylor Ford Jan 2021

Connecting Us, Taylor Ford

Architecture Theses

Imagine experiencing multiple different cities and cultures within a single day. In Europe, this is easily accessible, partly because of the close proximity and small scale of countries, but also because of their means of travel. The ease and speed of their train system make traveling between countries almost effortless, so what has prevented the United States from doing so as well? The distance, as the crow flies, from London to Paris is about 212 miles, similar to Fargo to Minneapolis at 207 miles. However, the drive from Fargo approaches four hours, whereas a train ride from London barely breaks …


Redefining The Cybernetic Being: Reconstructing The Theatrical Origins Of The Contemporary Metropolis, Samuel Goodman Jan 2021

Redefining The Cybernetic Being: Reconstructing The Theatrical Origins Of The Contemporary Metropolis, Samuel Goodman

Architecture Theses

We live in the information age. This means that our collective existence lies within a global society supported by an economy that is almost entirely structured by information technology, the study or use of systems for storing, retrieving, and sending information. This has led to a modernization of global data into a rigid system of, inputs and outputs. We have all unknowingly become an array of transistors in a system based on efficiency and results. The introduction of developments in the field of Artificial Intelligence has resulted in an even more systemic process whose sole purpose is to see the …


Understanding Programmed Cell Death Pathways By Characterizing Barley Disease Lesion Mimic Mutants, Wail Alsolami Jan 2021

Understanding Programmed Cell Death Pathways By Characterizing Barley Disease Lesion Mimic Mutants, Wail Alsolami

Plant Pathology

Programmed cell death (PCD) in plants refers to rapid and localized cell death that occurs as a result of regular biological processes, or in response to infection or injury. Understanding the molecular mechanisms of PCD will fill key knowledge gaps in regard to plant development or resistance mechanisms. Upon pathogen invasion salicylic acid and reactive oxygen intermediate (ROI) signaling responses are triggered that contribute to the PCD outcome. Substantial research efforts have been conducted to identify genes involved in these PCD pathways including the generation and characterization of disease lesion mimic mutants (DLMMs) that spontaneously express PCD and necrotic lesions …


Herbicide Screening In Industrial Hemp (Cannabis Sativa L.) Production, Joseph Eric Mettler Jan 2021

Herbicide Screening In Industrial Hemp (Cannabis Sativa L.) Production, Joseph Eric Mettler

Plant Sciences

Lack of labeled herbicides for industrial hemp (Cannabis sativa L.) production in the U.S. accentuates urgency to identify herbicides for weed control. Weed competition reduced seed yield by 25 to 32%. Pre- and post-emergence herbicide experiments were conducted to evaluate hemp tolerance to herbicides and support efforts for herbicide registrations. For post-emergence herbicides, hemp response to clopyralid (105 g ae ha-1) and bromoxynil (280 g ae ha-1) exhibited the lowest phytotoxicity, up to 38%, with no reduction of yield compared with the hand-weeded check. Pre-emergence herbicides were more viable options because pendimethalin (1120 g ai ha-1), trifluralin (840 g ai …


Dual Role Of Phenolic Bioactives In Improving Functional Health Benefits And Abiotic Stress Resilience In Barley, Ramnarain Ramakrishna Jan 2021

Dual Role Of Phenolic Bioactives In Improving Functional Health Benefits And Abiotic Stress Resilience In Barley, Ramnarain Ramakrishna

Plant Sciences

Food insecurity, climate change, and public health challenges are interconnected and pressing issues facing humanity in the 21st century. Therefore, it is imperative to address key obstacles underlying food and nutritional insecurity by developing strategies to concurrently improve the nutritional benefits and environmental stress resilience of food crops. The metabolic and physiological roles of plant-derived phenolic compounds are particularly relevant in addressing these challenges. Phenolic compounds are an integral part of plant adaptive defense responses against biotic and abiotic stresses. When consumed as part of diet, certain phenolic compounds from plant-based foods also provide wider protection against metabolic breakdowns and …


Balaam In The Book Of Numbers, Dana M. Pike Jan 2021

Balaam In The Book Of Numbers, Dana M. Pike

Faculty Publications

Balaam, the non-Israelite who prophesied positively about the Israelites, remains an enigmatic biblical figure, at least in part, because we cannot fully or confidently answer several important questions about him. The account of Balaam in Numbers 22–24 is oddly unique and reads like an independent unit, but it connects in several ways with the content and themes of the rest of the book of Numbers. So, however this account developed and was incorporated into the book of Numbers, it can at least be appreciated as part of the organic whole of the book.