Digital Commons Network^™

Importance Of Grazing Management In Improving Water Use Efficiency Of Tropical Forage Grasses, Juan A. Cardoso, J. D. L. C. Jiménez, Mauricio Sotelo, Idupulapati M. Rao, Michael Peters

IGC Proceedings (1977-2023)

The growing number of extreme weather events has created the need to identify tropical forage grasses with greater water use efficiency (WUE) to cope with water-limited conditions. WUE can be defined as the ratio of forage biomass produced per unit of water used. However, WUE is a dynamic ratio that changes according to environmental gradients (e.g., water or nutrient availability) or ontogenetic drift (e.g., changes in root to shoot biomass allocation across phenological stages). Furthermore, genetic improvement leading to greater WUE is likely to result in smaller plants that produce less than the required forage biomass to sustain good animal …

Risk Of Climate-Related Impacts On Global Rangelands – A Review And Modelling Study, C. M. Godde, R. B. Boone, A. Ash, K. Waha, L. Sloat, P. Thornton, D. Mason-D’Croz, D. Mayberry, M. Herrero

IGC Proceedings (1977-2023)

Climate change threatens the ability of global rangelands to provide food, support livelihoods and deliver important ecosystems services. The extent and magnitude of potential impacts are however poorly understood. In this study, we review the risk of climate impacts along the rangeland systems food supply chain. We also present results from biophysical modelling simulations and spatial data analyses to identify where and to what extent rangelands may be at climatic risk. Although a quantification of the net impacts of climate change on rangeland production systems is beyond the reach of our current understanding, there is strong evidence that there will …

Differential Effects Of Changed Precipitation Patterns On Co-Existing Dominant Species In Inner Mongolia Typical Grassland: Significance For Drought Management, S-X. Zhou, D-X. Wu

IGC Proceedings (1977-2023)

More extreme precipitation patterns are occurring worldwide in the context of global climate change. These patterns are characterized by larger event size separated by longer within-season drought periods, which are novel climatic conditions to many ecosystems while their consequences are largely unknown. Consequences of changed precipitation patterns on grassland could be complex since the effects of precipitation interval and total precipitation quantity can interact greatly with each other, and can differ among co-existing dominant species. Meanwhile, few researches explored the impacts of changed precipitation patterns on the hidden half – grassland root system. The objective of this study is to …

Cactus Forage Productivity Modelling Using Phygrow Software In A Semiarid Environment, M. J. D. Cândido, S. R. Maranhão, G. G. L. Araújo, A. Macedo, F. S. Campos, T. G. S. Silva

IGC Proceedings (1977-2023)

Plant growth modeling has been shown an increasing strategy to cope with the high demand for food supply, mainly in climate vulnerable areas, providing them to be used in agriculture worldwide. Concerning semiarid regions, the PHYGROW software has been promising to model plant growth, as cactus forage (‘Opuntia stricta’ cv. “Mexican elephant ear”) which was used in this study. Production data from 2017 and 2018 in Petrolina, Permambuco state, Brazil, with 12 replicates each year were considered. This region shows a very hot and dry climate and has an erratic and seasonal rainfall, which varies a lot in quantity, frequency …

Quantifying Greenhouse Gas Emissions Attributable To Smallholder Livestock Systems In Western Kenya: Cradle To Farm Gate Life Cycle Assessment, P. W. Ndung’U, T. Takahashi, C. J. L. Du Toit, M. Robertson-Dean, K. Butterbach-Bahl, G. Mcauliffe, L. Merbold, J. P. Goopy

IGC Proceedings (1977-2023)

Ruminants are central to the economic and nutritional life of much of sub-Saharan Africa, but cattle are now blamed for having disproportionately large negative environmental impact through (amongst other things) emissions of greenhouse gases. However, the exact mechanism behind these emissions is not well-understood and indeed accurate estimates themselves are lacking due to a paucity of reliable data. Employing individual animal records obtained at regular farm visits, this study quantified emissions intensities (EIs) of smallholder farms in three counties of Western Kenya through life cycle assessment (LCA). Crude protein (CP) was chosen as the functional unit to capture outputs of …

Long-Term N Addition, Not Warming, Increases Net Ecosystem Co2 Exchange In A Desert Steppe In Northern China, Guodong Han, Qian Wu

IGC Proceedings (1977-2023)

Grasslands cover a major part of the global terrestrial area and provide important ecosystem functions such as sequestration of carbon (C). Desert steppes are unique ecosystems with properties in between desert and grasslands. They are considered to be vulnerable ecosystems that are at risk of desertification due to global change. To provide a robust prediction of the effect of climate warming and increased nitrogen (N) deposition on desert steppe, long-term studies that capture the annual variation in precipitation are needed. We conducted a 12-year field experiment in a desert steppe which showed that warming did not change ecosystem C exchange …

Exploring Water Use And Production Dynamics Of Indigenous Protected Sikumi Forest In South Western Zimbabwe, O. Gwate

IGC Proceedings (1977-2023)

Monitoring changes in carbon and water vapour fluxes over a landscape helps in understanding ecosystem functioning and improves vegetation management. To understand potential shifts in ecosystem functioning, MoDerate Resolution Imaging Spectroradiometer (MODIS) evapotranspiration (ET), net photosynthesis, gross primary production and net primary production data were explored in Sikumi forest dominated by three species clusters (Teak forest woodland, Miombo woodland and savannah, and Vachellia). Measures of ecosystem stability including water use efficiency (WUE), rainfall use efficiency (RUE), evaporative index, and carbon use efficiency (CUE) were assessed for trends and step changes together with rainfall and evapotranspiration data. Miombo woodland and …

Synergistic Anticancer Response Of Curcumin And Piperine Loaded Lignin-G-P (Nipam-Co-Dmaema) Gold Nanogels Against Glioblastoma Multiforme, Xinyi Zhao, Bilal Javad, Daxing Cui, James Curtin, Furong Tian

Articles

Glioblastoma multiforme (GBM) is the most aggressive and commonly diag- 11 nosed brain cancer and presents a strong resistance to routine chemotherapeutic drugs. 12 The present study involves the synthesis of Lignin-g- p (NIPAM-co-DMAEMA) gold 13 nanogel, loaded with curcumin and piperine to treat GBM. The application has three 14 functions: (1) overcome the limitations of biodistribution, (2) enhance the toxicity of an- 15 ticancer drugs against GBM, (3) identify the uptake pathway. Atom transfer radical 16 polymerization was used to synthesize the Lignin-g-PNIPAM network, crosslinked with 17 the gold nanoparticles (GNPs) to self-assemble into nanogels. The size distribution and …

Enhanced Anticancer Response Of Curcumin- And Piperine-Loaded Lignin-G-P (Nipam-Co-Dmaema) Gold Nanogels Against U-251 Mg Glioblastoma Multiforme, Bilal Javed, Xinyi Zhao, Daxiang Cui, James Curtin, Furong Tian

Articles

Glioblastoma multiforme (GBM) is the most aggressive and commonly diagnosed brain cancer and is highly resistant to routine chemotherapeutic drugs. The present study involves the synthesis of Lignin-g-p (NIPAM-co-DMAEMA) gold nanogel, loaded with curcumin and piperine, to treat GBM. The ongoing study has the application potential to (1) overcome the limitations of drugs biodistribution, (2) enhance the toxicity of anticancer drugs against GBM, and (3) identify the drugs uptake pathway. Atom transfer radical polymerization was used to synthesize the Lignin-g-PNIPAM network, crosslinked with the gold nanoparticles (GNPs) to self-assemble into nanogels. The size distribution and morphological analysis confirmed that the …

Medical School Watercooler Newsletter - October 21, 2021, Lindsey Lyle

Watercooler Newsletter

This is the October 21, 2021 edition of the Frederick P. Whiddon College of Medicine's newsletter - Watercooler.

Contents include:

• Meet a Med Student: Cayla Van Alstine
• Faculty Spotlight: Jon Audia, Ph.D.
• Construction begins on ambulatory surgery center in Baldwin County
• Apply now: Clinical and Translational Science Training Program
• Employees honored at USA Health Game Day 2021

Better Tired Than Lost: Turtle Ant Trail Networks Favor Coherence Over Short Edges, Arjun Chandrasekhar, James A. R. Marshall, Cortnea Austin, Saket Navlakha, Deborah M. Gordon

Student Published Works

Creating a routing backbone is a fundamental problem in both biology and engineering. The routing backbone of the trail networks of arboreal turtle ants (Cephalotes goniodontus) connects many nests and food sources using trail pheromone deposited by ants as they walk. Unlike species that forage on the ground, the trail networks of arboreal ants are constrained by the vegetation. We examined what objectives the trail networks meet by comparing the observed ant trail networks with networks of random, hypothetical trail networks in the same surrounding vegetation and with trails optimized for four objectives: minimizing path length, minimizing average …

In-Season Concussion Symptom Reporting In Male And Female Collegiate Rugby Athletes, Emily E. Kieffer,, P. Gunnar Brolinson, Arthur C. Maerlender, Eric Smith, Steven Rowson

Center for Brain, Biology, and Behavior: Faculty Publications

Symptom inventories are generally only collected after a suspected concussion, but regular in-season monitoring may allude to clinical symptoms associated with repetitive subconcussive impacts and potential undiagnosed concussions. Despite sex-specific differences in symptom presentation and outcome of concussion, no return-to-play protocol takes sex into account. The objective of this study was to monitor a cohort of contact-sport athletes and compare the frequency and severity of in-season concussion-like symptom reporting between sexes. Graded symptom checklists from 144 female and 104 male athlete-seasons were administered weekly to quantify the effect of subconcussive impacts on frequency and severity of in-season symptom reporting. In-season, …

Improved Radiation Expression Profiling In Blood By Sequential Application Of Sensitive And Specific Gene Signatures, Eliseos J. Mucaki, Ben C. Shirley, Peter K. Rogan

Biochemistry Publications

Purpose. Combinations of expressed genes can discriminate radiation-exposed from normal control blood samples by machine learning based signatures (with 8 to 20% misclassification rates). These signatures can quantify therapeutically-relevant as well as accidental radiation exposures. The prodromal symptoms of Acute Radiation Syndrome (ARS) overlap those present in Influenza and Dengue Fever infections. Surprisingly, these human radiation signatures misclassified gene expression profiles of virally infected samples as false positive exposures. The present study investigates these and other confounders, and then mitigates their impact on signature accuracy.

Methods. This study investigated recall by previous and novel radiation signatures independently derived …

Genetic Targeting Of Adult Renshaw Cells Using A Calbindin 1 Destabilized Cre Allele For Intersection With Parvalbumin Or Engrailed1, Alicia R. Lane, Indeara C. Cogdell, Thomas M. Jessell, Jay B. Bikoff, Francisco J. Alvarez

Neuroscience, Cell Biology & Physiology Faculty Publications

Renshaw cells (RCs) are one of the most studied spinal interneurons; however, their roles in motor control remain enigmatic in part due to the lack of experimental models to interfere with RC function, specifically in adults. To overcome this limitation, we leveraged the distinct temporal regulation of Calbindin (Calb1) expression in RCs to create genetic models for timed RC manipulation. We used a Calb1 allele expressing a destabilized Cre (dgCre) theoretically active only upon trimethoprim (TMP) administration. TMP timing and dose influenced RC targeting efficiency, which was highest within the first three postnatal weeks, but specificity was low with …

Ontogeny Of Carbon Monoxide-Related Gene Expression In A Deep-Diving Marine Mammal, Elizabeth R. Piotrowski, Michael S. Tift, Daniel E. Crocker, Anna B. Pearson, José P. Vázquez-Medina, Anna D. Keith, Jane I. Khudyakov

Pacific Faculty Work

Marine mammals such as northern elephant seals (NES) routinely experience hypoxemia and ischemia-reperfusion events to many tissues during deep dives with no apparent adverse effects. Adaptations to diving include increased antioxidants and elevated oxygen storage capacity associated with high hemoprotein content in blood and muscle. The natural turnover of heme by heme oxygenase enzymes (encoded by HMOX1 and HMOX2) produces endogenous carbon monoxide (CO), which is present at high levels in NES blood and has been shown to have cytoprotective effects in laboratory systems exposed to hypoxia. To understand how pathways associated with endogenous CO production and signaling change across …

Pairwise Correlation Analysis Of The Alzheimer’S Disease Neuroimaging Initiative (Adni) Dataset Reveals Significant Feature Correlation, Erik D. Huckvale, Matthew W. Hodgman, Brianna B. Greenwood, Devorah O. Stucki, Katrisa M. Ward, Mark T. W. Ebbert, John S. K. Kauwe, The Alzheimer’S Disease Neuroimaging Initiative, The Alzheimer’S Disease Metabolomics Consortium, Justin B. Miller

Sanders-Brown Center on Aging Faculty Publications

The Alzheimer’s Disease Neuroimaging Initiative (ADNI) contains extensive patient measurements (e.g., magnetic resonance imaging [MRI], biometrics, RNA expression, etc.) from Alzheimer’s disease (AD) cases and controls that have recently been used by machine learning algorithms to evaluate AD onset and progression. While using a variety of biomarkers is essential to AD research, highly correlated input features can significantly decrease machine learning model generalizability and performance. Additionally, redundant features unnecessarily increase computational time and resources necessary to train predictive models. Therefore, we used 49,288 biomarkers and 793,600 extracted MRI features to assess feature correlation within the ADNI dataset to determine the …

Micrornas As Biomarkers For Early Diagnosis, Prognosis, And Therapeutic Targeting Of Ovarian Cancer, Yegane Mirahmadi, Reza Nabavi, Fourough Taheri, Mohammad Mahdi Samadian, Zari Naderi Ghale-Noie, Mahsa Farjami, Abbas Samadi-Khouzani, Meysam Yousefi, Sara Azhdari, Arash Salmaninejad, Amirhossein Sahebkar

Department of Animal Science: Faculty Publications

Ovarian cancer is the major cause of gynecologic cancer-related mortality. Regardless of outstanding advances, which have been made for improving the prognosis, diagnosis, and treatment of ovarian cancer, the majority of the patients will die of the disease. Late-stage diagnosis and the occurrence of recurrent cancer after treatment are the most important causes of the high mortality rate observed in ovarian cancer patients. Unraveling the molecular mechanisms involved in the pathogenesis of ovarian cancer may help find new biomarkers and therapeutic targets for ovarian cancer. MicroRNAs (miRNAs) are small noncoding RNAs that regulate gene expression, mostly at the posttranscriptional stage, …

10-21-2021 Swosu Bull Pup Camps Planned Homecoming Saturday Morning For Area Youth, Southwestern Oklahoma State University

THE BARK ARCHIVE 2021

No abstract provided.

Conquer And Prevail Issue 85 October 21 2021, Wofford College. Office Of Marketing And Communications

Conquer and Prevail Newsletter

No abstract provided.

Perches As Cooling Devices For Reducing Heat Stress In Caged Laying Hens: A Review, Jiaying Hu, Yijie Xiong

Department of Animal Science: Faculty Publications

Heat stress is one of the most detrimental environmental challenges affecting the biological process and the related production performance of farm animals, especially in poultry. Commercial laying hens have been bred (selected) for high egg production, resulting in increased sensitivity to heat stress due to breeding-linked metabolic heat production. In addition, laying hens are prone to heat stress due to their inadequate species-specific cooling mechanisms resulting in low heat tolerance. In addition, hens have no sweat glands and feathering covers almost their entire body to minimize body heat loss. The poultry industry and scientists are developing cooling methods to prevent …

Multimedia Open Educational Resource Materials For Teaching-Online Diversity And Leadership: Aligning Bloom’S Taxonomy And Studio Habits Of Mind, Elizabeth Johnston, Cheryl Burleigh, Xeno Rasmusson, Patrick Turner, Drena Valentine, Liston Bailey

Higher Learning Research Communications

Objective: The purpose of this study was to explore, develop, test, and refine processes to incorporate meaningful and equitable use of open educational resources (OER) in online classrooms.

Method: The intent of this qualitative study was to use an action research process of interactive discussions between higher education practitioners to shape collective understanding of how to teach in an online learning environment using OER.

Results: The study resulted in the identification six exemplar learning opportunities which could be incorporated into the blended pedagogical model. Each exemplar OER included all four types of knowledge as defined by Bloom's taxonomy and required …

Steven N. Austad, Ph.D., Appointed As Inaugural Protective Life Endowed Chair In Healthy Aging Research At Uab, Staff

Browse All News

No abstract provided.

Inheritance Of A Mutation Causing Neuropathy With Splayed Forelimbs In Jersey Cattle, A. Al-Khudhair, D. J. Null, J. B. Cole, C. W. Wolfe, David J. Steffen, P. M. Vanraden

School of Veterinary and Biomedical Sciences: Faculty Publications

A new undesirable genetic factor, neuropathy with splayed forelimbs (JNS), has been identified recently in the Jersey breed. Calves affected with JNS are unable to stand on splayed forelimbs that exhibit significant extensor rigidity and excessive lateral abduction at birth. Affected calves generally are alert at birth but exhibit neurologic symptoms, including spasticity of head and neck and convulsive behavior. Other symptoms reported include dislocated shoulders, congenital craniofacial anomalies, and degenerative myelopathy. Inheritance of an undesirable genetic factor was determined from a study of 16 affected calves reported by Jersey breeders across the United States. All of their pedigrees traced …

Distributed Subnetworks Of Depression Defined By Direct Intracranial Neurophysiology, Katherine Wilson Scangos, Ankit N. Khambhati, Patrick M. Daly, Lucy W. Owen, Jeremy R. Manning, Josiah B. Ambrose, Everett Austin, Heather E. Dawes, Andrew D. Krystal, Edward F. Chang

Dartmouth Scholarship

Major depressive disorder is a common and disabling disorder with high rates of treatment resistance. Evidence suggests it is characterized by distributed network dysfunction that may be variable across patients, challenging the identification of quantitative biological substrates. We carried out this study to determine whether application of a novel computational approach to a large sample of high spatiotemporal resolution direct neural recordings in humans could unlock the functional organization and coordinated activity patterns of depression networks. This group level analysis of depression networks from heterogenous intracranial recordings was possible due to application of a correlational model-based method for inferring whole-brain …

Hawks' Herald -- Oct. 21, 2021, Roger Williams University

Hawk's Herald

No abstract provided.

Interview With Espoir Habimana, Espoir Habimana, Dan Raleigh

Interviews

Transcript of interview and audio recording conducted with Espoir Habimana. Per the "Methodology" section, the transcript has been lightly edited for clarity. The interview begins at 00:15:16 in the audio recording.

This interview was recorded over Zoom and manually transcribed.

October 21, 2021, James Madison University

The Breeze, 2020-

The Breeze is the student newspaper of James Madison University in Harrisonburg, Virginia.

Regularized Heuristic Method For Activation Monitor Neutron Spectrum Unfolding, Nicholas J. Quartemont, James E. Bevins

Faculty Publications

his paper describes an activation foil measurement based neutron flux unfolding method utilizing a heuristic optimization approach. A regularization parameter based on the differential neutron flux was introduced into the optimization cost function to remove large nonphysical oscillations in the unfolded neutron energy spectrum. The procedure was completed for two example case studies ranging from thermal energies up to 20 MeV demonstrating recovery of neutron flux energy information on radiation environments where a model was partially missing or there was a discrepancy in a reaction channel. The unfolded results provided a distribution of unfolded spectra that conformed to the activation …

Early Gestational Profiling Of Oxidative Stress And Angiogenic Growth Mediators As Predictive, Preventive And Personalised (3p) Medical Approach To Identify Suboptimal Health Pregnant Mothers Likely To Develop Preeclampsia, Enoch O. Anto, David A. Coall, Otchere Addai-Mensah, Yaw Amo Wiafe, William K. B. A. Owiredu, Christian Obirikorang, Max E. Annani-Akollor, Eric Adua, Augustine Tawiah, Emmanuel Acheampong, Evans Adu Asamoah, Xueqing Wang, Stephen Opoku, Derick Kyei Boakye, Haifeng Hou, Youxin Wang, Wei Wang

Research outputs 2014 to 2021

Pregnant women, particularly in developing countries are facing a huge burden of preeclampsia (PE) leading to high morbidity and mortality rates. This is due to delayed diagnosis and unrecognised early targeted preventive measures. Adapting innovative solutions via shifting from delayed to early diagnosis of PE in the context of predictive diagnosis, targeted prevention and personalisation of medical care (PPPM/3 PM) is essential. The subjective assessment of suboptimal health status (SHS) and objective biomarkers of oxidative stress (OS) and angiogenic growth mediators (AGMs) could be used as new PPPM approach for PE; however, these factors have only been studied in isolation …

Updating The Distribution Of American Black Bears (Ursus Americanus) In Texas Using Community Science, State Agencies, And Natural History Collections, Jessica E. Light, Alaya S. Keane, Jonah W. Evans

Western North American Naturalist

The American black bear (Ursus americanus) is one of largest terrestrial mammals found in Texas. Despite the black bear’s large size and charismatic nature, its distribution across the state has been difficult to determine due to outdated distribution maps. Although recent sighting reports indicate that the current distribution of black bears in Texas may be expanding in some areas, researching changes in black bear populations can be difficult and cost prohibitive. Data from community science initiatives and natural history collections can be useful to better understand species distributions and ecology. We used records from Texas Parks and Wildlife …