Digital Commons Network^™

Aurora-A Kinase Is Differentially Expressed In The Nucleus And Cytoplasm In Normal Müllerian Epithelium And Benign, Borderline And Malignant Serous Ovarian Neoplasms, Khaled J. Alkhateeb, Jason E. Crane, Müge Sak, Caitlin J. Jorgensen, James P. O'Donnell, Cory T. Zumbar, Jason A. Wozniak, Clarence R. Salazar, Anil V. Parwani, Norman L. Lehman

Pathology and Laboratory Medicine Articles

BACKGROUND: Aurora-A kinase is important for cellular proliferation and is implicated in the tumorigenesis of several malignancies, including of the ovary. Information regarding the expression patterns of Aurora-A in normal Müllerian epithelium as well as benign, borderline and malignant epithelial ovarian neoplasms is limited.

METHODS: We investigated Aurora-A expression by immunohistochemistry in 15 benign, 19 borderline and 17 malignant ovarian serous tumors, and 16 benign, 8 borderline, and 2 malignant ovarian mucinous tumors. Twelve fimbriae from seven patients served as normal Müllerian epithelium controls. We also examined Aurora-A protein expression by western blot in normal fimbriae and tumor specimens.

RESULTS: …

Faculty Senate Agenda

Faculty Senate Agendas

No abstract provided.

Decoding The Equine Genome: Lessons From Encode, Sichong Peng, Jessica L. Petersen, Rebecca R. Bellone, Theodore S. Kalbfleisch, N. B. Kingsley, Alexa M. Barber, Eleonora Cappelletti, Elena Giulotto, Carrie J. Finno

Veterinary Science Faculty Publications

The horse reference genome assemblies, EquCab2.0 and EquCab3.0, have enabled great advancements in the equine genomics field, from tools to novel discoveries. However, significant gaps of knowledge regarding genome function remain, hindering the study of complex traits in horses. In an effort to address these gaps and with inspiration from the Encyclopedia of DNA Elements (ENCODE) project, the equine Functional Annotation of Animal Genome (FAANG) initiative was proposed to bridge the gap between genome and gene expression, providing further insights into functional regulation within the horse genome. Three years after launching the initiative, the equine FAANG group has generated data …

Twenty Years After The Anthrax Terrorist Attacks Of 2001: Lessons Learned And Unlearned For The Covid-19 Response, Lawrence O. Gostin, Jennifer B. Nuzzo

Georgetown Law Faculty Publications and Other Works

The 20th anniversary of the terrorist attacks on September 11, 2001, resulted in deep national reflection. Less remembered are the events that began to unfold 7 days later as anonymous letters laced with deadly anthrax (Bacillus anthracis) spores began arriving at postal facilities, media companies, and congressional offices. The first death from inhaled anthrax exposure occurred on October 5, with an additional 4 deaths and 17 infections over the ensuing months.

The anthrax attacks exposed a health system ill-equipped to respond to acute emergencies. This article explores the lessons learned, and unlearned, from the anthrax attacks, through to …

Moving Conferences Online: Lessons Learned From An International Virtual Meeting, Paris V. Stefanoudis, Leann M. Biancani, Sergio Cambronero-Solano, Malcolm R. Clark, Jonathan T. Copley, Erin E. Easton, Franziska Elmer, Steven H. D. Haddock, Santiago Herrera, Ilysa S. Iglesias

School of Earth, Environmental, & Marine Sciences Faculty Publications

We consider the opportunities and challenges associated with organizing a conference online, using a case study of a medium-sized (approx. 400 participants) international conference held virtually in August 2020. In addition, we present quantifiable evidence of the participants’ experience using the results from an online post-conference questionnaire. Although the virtual meeting was not able to replicate the in-person experience in some aspects (e.g. less engagement between participants) the overwhelming majority of respondents found the meeting an enjoyable experience and would join similar events again. Notably, there was a strong desire for future inperson meetings to have at least some online …

Photography And Modern Public Housing In Los Angeles, Nicole Krup Oest

Faculty Research, Scholarly, and Creative Activity

In the 1940s, Los Angeles faced an acute housing crisis. The local housing authority responded with a controversial program of slum clearance and public housing, as well as photography that presented the crisis in innovative ways. This book brings this photography together with previously unpublished sources to uncover a largely unexamined concept of home photography. Case studies from Los Angeles, New York and Berlin along with FBI records and almost forgotten bulletins invite a new understanding of the history of housing and photography, in which scientists and photographers played central roles.

Non-Poissonian Ultrashort Nanoscale Electron Pulses, Sam Keramati, Will Brunner, T. J. Gay, Herman Batelaan

Department of Physics and Astronomy: Faculty Publications

The statistical character of electron beams used in current technologies, as described by a stream of particles, is random in nature. Using coincidence measurements of femtosecond pulsed electron pairs, we report the observation of sub-Poissonian electron statistics that are nonrandom due to two-electron Coulomb interactions, and that exhibit an antibunching signal of 1 part in 4. This advancement is a fundamental step toward observing a strongly quantum degenerate electron beam needed for many applications, and in particular electron correlation spectroscopy.

Behaviour Investigation Of Sma-Equipped Bar Hysteretic Dampers Using Machine Learning Techniques, Visar Farhangi, Hashem Jahangir, Danial Rezazadeh Eidgahee, Arash Karimipour, Seyed Alireza Nedaei Javan, Hamed Hasani, Nazanin Fasihihour, Moses Karakouzian

Civil and Environmental Engineering and Construction Faculty Research

Most isolators have numerous displacements due to their low stiffness and damping properties. Accordingly, the supplementary damping systems have vital roles in damping enhancement and lower the isolation system displacement. Nevertheless, in many cases, even by utilising additional dampers in isolation systems, the occurrence of residual displacement is inevitable. To address this issue, in this study, a new smart type of bar hysteretic dampers equipped with shape memory alloy (SMA) bars with recentring features, as the supplementary damper, is introduced and investigated. In this regard, 630 numerical models of SMA-equipped bar hysteretic dampers (SMA-BHDs) were constructed based on experimental samples …

Workplace Bullying: Exploring The Prevalence, Impact, And Consequences To Nurses, Peggy Ann Berry

Dissertations

Most novice nurses will experience workplace bullying (WPB) behaviors within 1-2 years of licensure. This exposure adversely affects work productivity. The purposes of this study were to (1) explore factors that resulted in the adoption of WPB behaviors; (2) determine the differences in perceived stress, anxiety state, and posttraumatic stress symptoms based on bullying exposure frequencies and select nurse characteristics; and (3) explore strategies to manage or stop WPB behaviors.

Patel'23 Research Bird Eyes Using Antibody Staining Techniques, Kailee Galloway

News and Events (Discontinued Series)

No abstract provided.

A Drone-Based Survey For Large, Basking Freshwater Turtle Species, Amy P. Bogolin, Drew R. Davis, Richard Kline, Abdullah Rahman

School of Earth, Environmental, & Marine Sciences Faculty Publications

Conservation concerns are increasing for numerous freshwater turtle species, including Pseudemys gorzugi, which has led to a call for more research. However, traditional sampling methodologies are often time consuming, labor intensive, and invasive, restricting the amount of data that can be collected. Biases of traditional sampling methods can further impair the quality of the data collected, and these shortfalls may discourage their use. The use of unmanned aerial vehicles (UAVs, drones) for conducting wildlife surveys has recently demonstrated the potential to bridge gaps in data collection by offering a less labor intensive, minimally invasive, and more efficient process. Photographs and …

High Seropositivity Rate Of Neutralizing Antibodies To Astrovirus Va1 In Human Populations, Andrew B Janowski, Macee C Owen, Holly Dudley, Tomás López, Rafaela Espinosa, Memory Elvin-Lewis, Alejandro Colichon, Carlos F Arias, Peter D Burbelo, David Wang

Open Access Publications

Astroviruses are common pathogens of the human gastrointestinal tract, but they have been recently identified from cases of fatal meningoencephalitis. Astrovirus VA1 is the most frequently detected astrovirus genotype from cases of human encephalitis, but the prevalence of neutralizing antibodies to VA1 in human sera is unknown. We developed a focus reduction neutralization assay (FRNT) for VA1 and measured the seroprevalence of neutralizing antibodies from two cohorts of adult and pediatric serum samples: (i) an age-stratified cohort from St. Louis, MO, collected from 2007 to 2008 and (ii) a cohort from the Peruvian Amazonian River Basin collected in the late …

Expansion-Contraction: Spatial And Temporal Variability In Connectivity In A Stream-Wetland Flow Network, Savannah Fransbergen

USF Tampa Graduate Theses and Dissertations

The seasonal expansion and contraction in a stream-wetland flow network is often difficult to characterize due to a lack of accurate mapping products, but proper characterization is important for the management of these resources. A new approach to mapping hydrography, resulting in a Regional Hydrography Dataset (RHD), may offer additional insights not provided by the national standard, the National Hydrography Dataset (NHD). The RHD can be customized to provide seasonal or monthly hydrograph, whereas the NHD is static. We conducted field validation (241 sites) and geospatial analyses to assess the accuracy of these products in the northern Tampa Bay Area. …

Effects Of Nitrate On Arsenic Mobilization During Aquifer Storage And Recovery, Hania Hawasli

USF Tampa Graduate Theses and Dissertations

Aquifer storage and recovery technology is used to sustain water resources and to prevent saltwater intrusion. The injected water can come from various resources, including treated wastewater. In pilot ASR studies in the Tampa Bay region, researchers found high As concentrations in the recovered water from the oxidation of the arsenopyrite that is embedded in the aquifers. The presence of dissolved O2 in the injected water is a major factor in the arsenopyrite oxidation during ASR, however the effects of NO3- on the arsenopyrite has not been studied yet. This is an important knowledge gap because injected water may contain …

Plasma Treatment Of High-Density Polyethylene, Linear Low-Density Polyethylene, And Polyvinyl Chloride Geomembranes By Air And Oxygen, Merve Koca Uyar

USF Tampa Graduate Theses and Dissertations

High-density polyethylene (HDPE), linear low-density polyethylene (LLDPE), and polyvinyl chloride (PVC) geomembranes were treated with air and oxygen plasma. The purpose of air and oxygen plasma treatment of geomembrane surface is to increase the surface wettability of these materials, thereby increasing adhesive properties. Increasing adhesive properties enables a surface to be coated with a desired material with antibacterial, antioxidant, and UV resistant characteristics, without changing bulk material properties. To protect the geomembranes from oxidation degradation, UV degradation and biological degradation, it is important to increase the antibacterial, antioxidant, and UV resistant properties of geomembrane. Before and after the plasma treatments …

The Multifaceted Role Of Ccar-1 In The Alternative Splicing And Germline Regulation In Caenorhabditis Elegans, Doreen Ikhuva Lugano

USF Tampa Graduate Theses and Dissertations

The Cell Division Cycle and Apoptosis Regulator (CCAR) family members are an enigmatic family of proteins regulating metabolism, cancer, apoptosis, DNA damage, and stress. Mammals have CCAR family members, CCAR1 and CCAR2/DBC1, which evolved from the founding family member CCAR-1/LST-3 expressed in Caenorhabditis elegans. Several studies have shown the importance of understanding these proteins' function in standard and altered physiological processes. Our studies aim to understand the genome-wide alternative splicing and germline regulation of Caenorhabditis elegans CCAR-1 in normal and heat shock conditions. Recently, mammalian CCAR family member CCAR2/DBC1 regulates the alternative splicing by forming a complex with ZNF326. This …

Spartan Daily, October 27, 2021, San Jose State University, School Of Journalism And Mass Communications

Spartan Daily, 2021

Volume 157, Issue 30

Glycogen Storage Disease Type Ia: Current Management Options, Burden And Unmet Needs, Terry G J Derks, David F Rodriguez-Buritica, Ayesha Ahmad, Foekje De Boer, María L Couce, Sarah C Grünert, Philippe Labrune, Nerea López Maldonado, Carolina Fischinger Moura De Souza, Rebecca Riba-Wolman, Alessandro Rossi, Heather Saavedra, Rupal Naik Gupta, Vassili Valayannopoulos, John Mitchell

Faculty, Staff and Student Publications

Glycogen storage disease type Ia (GSDIa) is caused by defective glucose-6-phosphatase, a key enzyme in carbohydrate metabolism. Affected individuals cannot release glucose during fasting and accumulate excess glycogen and fat in the liver and kidney, putting them at risk of severe hypoglycaemia and secondary metabolic perturbations. Good glycaemic/metabolic control through strict dietary treatment and regular doses of uncooked cornstarch (UCCS) is essential for preventing hypoglycaemia and long-term complications. Dietary treatment has improved the prognosis for patients with GSDIa; however, the disease itself, its management and monitoring have significant physical, psychological and psychosocial burden on individuals and parents/caregivers. Hypoglycaemia risk persists …

The Structure Of Tardigrade Communities At Fine Spatial Scales In An Andean Polylepis Forest, Bpl Ramsay, Nigel J. Marley, David T. Bilton, Simon D. Rundle, Pm Ramsay

School of Biological and Marine Sciences

No abstract provided.

Dose-Escalated Magnetic Resonance Image-Guided Abdominopelvic Reirradiation With Continuous Intrafraction Visualization, Soft Tissue Tracking, And Automatic Beam Gating, Michael Chuong, John Bryant, James Mcculloch, Jessika Contreras, Rupesh Kotecha, Tino Romaguera, Diane Alvarez, Matthew Hall, Muni Rubens, Minesh Mehta, Adeel Kaiser, Martin Tom, Alonso Gutierrez, Kathryn Mittauer

All Publications

Purpose: Compared with computed tomography, magnetic resonance (MR) image guidance offers significant advantages for radiation therapy (RT) that may be particularly beneficial for reirradiation (reRT). However, clinical outcomes of MR-guided reRT are not well described in the published literature.

Methods and materials: We performed a single-institution retrospective safety and efficacy analysis of reRT patients treated on the MRIdian Linac to targets within the abdomen or pelvis using continuous intrafraction MR-based motion management with automatic beam triggering. Fiducial markers were not used.

Results: We evaluated 11 patients who received prior RT to a median of 50 Gy (range, 30-58.8 Gy) in …

Appressorium-Mediated Plant Infection By Magnaporthe Oryzae Is Regulated By A Pmk1-Dependent Hierarchical Transcriptional Network, Míriam Osés-Ruiz, Neftaly Cruz-Mireles, Magdalena Martin-Urdiroz, Darren M. Soanes, Alice Bisola Eseola, Bozeng Tang, Paul Derbyshire, Mathias Nielsen, Jitender Cheema, Vincent Were, Iris Eisermann, Michael J. Kershaw, Xia Yan, Guadalupe Valdovinos-Ponce, Camilla Molinari, George R. Littlejohn, Barbara Valent, Frank L.H. Menke, Nicholas J. Talbot

School of Biological and Marine Sciences

Rice blast is a devastating disease caused by the fungal pathogen Magnaporthe oryzae that threatens rice production around the world. The fungus produces a specialized infection cell, called the appressorium, that enables penetration through the plant cell wall in response to surface signals from the rice leaf. The underlying biology of plant infection, including the regulation of appressorium formation, is not completely understood. Here we report the identification of a network of temporally coregulated transcription factors that act downstream of the Pmk1 mitogen-activated protein kinase pathway to regulate gene expression during appressorium-mediated plant infection. We show that this tiered regulatory …

Replication Stress Response Defects Are Associated With Response To Immune Checkpoint Blockade In Nonhypermutated Cancers, Daniel J Mcgrail, Patrick G Pilié, Hui Dai, Truong Nguyen Anh Lam, Yulong Liang, Leonie Voorwerk, Marleen Kok, Xiang H-F Zhang, Jeffrey M Rosen, Amy B Heimberger, Christine B Peterson, Eric Jonasch, Shiaw-Yih Lin

Faculty, Staff and Students Publications

Treatment with immune checkpoint blockade (ICB) has resulted in durable responses for a subset of patients with cancer, with predictive biomarkers for ICB response originally identified largely in the context of hypermutated cancers. Although recent clinical data have demonstrated clinical responses to ICB in certain patients with nonhypermutated cancers, previously established ICB response biomarkers have failed to accurately identify which of these patients may benefit from ICB. Here, we demonstrated that a replication stress response (RSR) defect gene expression signature, but not other proposed biomarkers, is associated with ICB response in 12 independent cohorts of patients with nonhypermutated cancer across …

Proposals For Innovation And Improvement Of The Quality Of Life In Caprine Pastoralist Communities Of Subsistence In The Monte Desert, Argentina, E. M. Abraham, C. Rubio, D. Soria, L. Corso, A. Therburg, D. Bran, A. Maggi, P. Maccagno, C. Policastro, S. Verón, V. Pietragalla, M. Wilson

IGC Proceedings (1977-2023)

In a satisfactory alliance between the main environmental policy organizations and the academy, the National Observatory on Land Degradation and Desertification (ONDTyT) is created. The ONDTyD provides information regarding status and trends of land degradation/desertification in order to promote prevention and mitigation measures used for advising public and private decision-makers in Argentina. It is based in the development of 17 Pilot Sites that constitutes the local level network, providing bio-physical and socio-economic indicators of land degradation.

In this network the pilot site of the Monte, the largest dry region of Argentina (Lavalle desert, Mendoza), aims to improve the living conditions …

Open Science Bangladesh: An Update, Susmita Das

COAR Asia OA Meeting 2021

The pandemic is an opportunity to illustrate that Open Science practices, such as sharing the data from experiments and analysis, are doable to find successful treatments speedily. So while the pandemic is an appalling threat, it's also an amazing opening to transform research traditions. Realizing its importance for university and research potentiality, university libraries of Bangladesh permit OA to publish their content for internal and external members. This presentation attempts to explore the extent that Open Science activities being undertaken by various actors in line with UNESCO’s recommendation on Open Science in Bangladesh.

Tjlp, Vol.11 Special Issue Winter 2016

Tennessee Journal of Law and Policy

No abstract provided.

Participatory Observatories To Connect Multifunctional Landscapes, Link Smallholder Farmers, And Collectively Diversify Income, I. Espejel Carvajal, G. Romero, O. Pérez, R. Yaguez, Elisabeth Huber-Sannwald, N. Martínez Tagueña, C. L. Lauterio Martínez, V. M. Reyes Gómez, S. Lucatello

IGC Proceedings (1977-2023)

Cattle ranching was introduced to Baja California, Mexico (semiarid and arid climates) by the Spaniards, who brought the animals and the techniques. One important activity was moving livestock from the mountains (forests and few kinds of grass) to the coast crossing poor shrublands known as chaparrals. Fire was a common practice to promote grass growth and pastoralists could move through the land freely. Pastoralism became a common practice when English workers built the Ensenada port and became ranching landowners. They followed the practice of livestock movement through the exorreic watersheds. Native Indians, as well as other Mexicans known as ejidatarios, …

Participatory Management Of Rangeland Hydrology – A New Socio-Ecological Technology To Effectively Adapt To And Mitigate Climate Change: Case From Morocco, Lhoussaine Bouchaou, El Hassane El Mahdad, El Hassan Beraaouz, Abdelfettah Sifeddine, Alessandro Rizzo, Mohamed Hssaisoune, Hanane Reddad, Abdelghani Chehbouni, Elisabeth Huber-Sannwald

IGC Proceedings (1977-2023)

Morocco’s drylands cover over 90% of the land area; low and irregular rainfall and high potential evaporation contribute to extremely high-water deficits. These phenomena have greatly impacted rangeland hydrology and nomadic and transhumant pastoralism. To adapt to this predominant water deficit, the inhabitants of these areas have developed two forms of lifestyles, which include household and livestock mobility: (i) a pendulum movement for seasonal transhumance between the mountains and their bordering plains; and (ii) random nomadic mobility regulated by the sporadic frequency of rains and thus water availability. In both cases, this mobility is controlled by the degree of development …

Describing The Experiences Of Students With Adhd Learning Science Content With Emerging Technologies, Rebecca Hite, Gina Childers, Gail Jones, Elysa Corin, Mariana Pereyra

Journal of Science Education for Students with Disabilities

Emerging technologies, such as virtual reality, haptics, and 3-dimensionality, provide novel opportunities to allow students to investigate scientific phenomena by fostering perceptions of virtual presence, the feeling of being sensorially immersed and authentically interacting within a computer-generated virtual learning environment (VLE). Neurotypical learners are largely represented in VLE research on science learning, with fewer with neurodivergent learners, such as students with ADHD. This descriptive case study sought to address the dearth in the literature on neurodivergent students’ experiences, with emerging technologies, for learning science. Specifically, the case describes the extent to which neurodivergent learners experience the affordances of VLEs for …

Bale Grazing: Feeding Hay The Rotational Grazing Way, Gregory S. Halich

Kentucky Grazing Conference

Imagine a hay feeding system where you did not have to use a tractor for months at a time and that allowed you to build up pasture fertility without applying commercial fertilizer. Would this be of interest to you? What if this same system also kept your cattle clean during the winter without coats caked in mud and manure, allowed you to creep graze fall‐born calves, and built up the organic matter levels in your pasture soils. Would you be even more interested? As far‐fetched as this may sound, all these benefits are possible with an innovative winter‐feeding technique called …

Right Rate, Timing, Source And Placement: More Bang For The Pasture Fertilizer Buck, John H. Grove, Christopher D. Teutsch

Kentucky Grazing Conference

As we write this paper for the conference, fall fertilizer prices continue to increase, albeit at a slower pace than earlier this fall for most materials. The latest DTN retail price survey https://www.dtnpf.com/agriculture/web/ag/crops/article/2021/10/06/fertilizer‐price‐gains-losing‐steam has urea (46‐0‐0) at $620/ton, DAP (18‐46‐0) at $722/ton and potash (0‐ 0‐60) at $647/ton. This gives $0.675/lb N, $0.52/lb P₂O₅ (after the N value in DAP price was accounted for), and $0.54/lb K₂O. Compared to this time last year, urea, DAP and muriate of potash are 71, 64 and 92% higher, respectively. Other important materials used in Kentucky are also higher: …