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Point-Of-Care Ultrasound Assessment Of The Inferior Vena Cava Distensibility Index Inmechanically Ventilated Children In The Operating Room, Riza Di̇nçer Yildizdaş, Özden Özgür Horoz, Ahmet Yöntem, Faruk Eki̇nci̇, Vahi̇de Nagehan Aslan, Demet Lafli Tunay, Murat Türkeün Ilginel

Turkish Journal of Medical Sciences

Background and aim: Point-of-care ultrasound imaging of the inferior vena cava distensibility index is a potential indicator for determining fluid overload and dehydration in the mechanically ventilated patients. Data on inferior vena cava distensibility index and inferior vena cava distensibility variability are limited in mechanically ventilated pediatric patients. That is why our aim in this study was to measure inferior vena cava distensibility index and to obtain mean values in pediatric patients, ventilated in the operating room before the ambulatory surgical procedure started. Materials and methods: This crosssectional study was performed between February 2019 and February 2020. Ultrasonographic measurements were …

Prevalence Of Comorbidities And Associated Factors In Acromegaly Patients In The Turkishpopulation, Mustafa Can, Muhammet Kocabaş, İlker Çordan, Hati̇ce Çalişkan Burgucu, Meli̇a Karaköse, Mustafa Kulaksizoğlu, Feridun Karakurt

Turkish Journal of Medical Sciences

Background/aim: The presence of comorbidities in patients with acromegaly causes an increase in morbidity and/or mortality and a decrease in quality of life. In this study, we aimed to investigate the demographic, clinical and laboratory features, prevalence of acromegaly-related comorbidities, and factors associated with these comorbidities in patients with acromegaly. Materials and methods: In the study, 96 patients who were followed up with the diagnosis of acromegaly were included. Clinical, laboratory and imaging features, and accompanying comorbidities of the patients were recorded from the patient files. Results: Of the patients included in the study, 63 (65.6%) were female and 33 …

Comparison Of Frozen-Thawed Embryo Transfer Protocols In Patients With Previouscycle Cancellation Due To Uterine Peristalsis: A Pilot Study, İlknur Selvi̇, Mehmet Erdem, Erhan Demi̇rdağ, Müni̇re Funda Cevher Akdulum, Cengi̇z Karakaya, Ahmet Erdem

Turkish Journal of Medical Sciences

Background/aim: To investigate the optimal protocol for frozen-thawed embryo transfer (FET) cycles in patients who previously had a cycle cancellation due to uterine peristalsis (UP). Materials and methods: Thirty-four patients with previous embryo transfer (ET) cancellation due to UP during artificial cycle (AC) were included retrospectively. In the proceeding cycle, endometrium was prepared with AC (n: 23) in AC-FET group or with stimulated cycle that contains letrozole (L) (n: 11) in L-FET group. Intravenous bolus dose of 6.75 mg atosiban (Tractocile; Ferring Pharmaceuticals, Switzerland) injection was performed to all patients of AC-FET group due to UP ≥ 4/min on the …

The Effect Of Ankaferd Blood Stopper On Liver Damage In Experimental Obstructivejaundice, Koray Koşmaz, Abdullah Durhan, Marlen Süleyman, Yilmaz Ünal, Mustafa Taner Bostanci, Tuğba Yi̇ği̇t Haskaraca, Can Ersak, Mehmet Şeneş, İlknur Alkan Kuşabbi̇, Eylem Pinar Eser, Sema Hücümenoğlu

Turkish Journal of Medical Sciences

Background/aims: To evaluate the potential protective effects of Ankaferd blood stopper (ABS) in an experimental obstructive jaundice (OJ) model. Materials and methods: The study included 26 female rats, which were divided into 3 groups. The sham group, consisting of 10 rats, (group 1) only received solely laparotomy. In the control group, consisting of 8 rats, (group 2), ligation was applied to the biliary tract and no treatment was implemented. In the treatment group, consisting of 8 rats, (group 3), following ligation of biliary tract, 0.5 mL/day ABS was given for 10 days. Liver tissue and blood samples were taken for …

Effects Of The Covid-19 Pandemic On Psychology And Disease Activity In Patients Withankylosing Spondylitis And Rheumatoid Arthritis, Şaki̇r Gica, Yasemi̇n Akkubak, Zaki̇re Kübra Aksoy, Adem Küçük, Erkan Cüre

Turkish Journal of Medical Sciences

Background/aim: The COVID-19 outbreak is known to increase stress levels of most patients with chronic diseases. Patients with ankylosing spondylitis (AS) and rheumatoid arthritis (RA) are highly susceptible to environmental stress. In the current study, we aimed to determine how the COVID-19 pandemic psychologically affected patients with chronic progressive diseases such as AS and RA and the effects of these psychological factors on disease activity. Materials and methods: Age and sex-matched patients with AS (n = 80), RA (n = 80), and healthy controls (n = 80) were included in the study. All participants were evaluated with the "Perceived COVID-19 …

Attention-Deficit Hyperactivity Disorder Symptoms And Quality Of Life In Female Patientswith Fibromyalgia, Gözde Türkoğlu, Yavuz Selvi̇

Turkish Journal of Medical Sciences

Background/aim: The present study aimed to determine the association between attention-deficit hyperactivity disorder (ADHD) symptoms severity, fibromyalgia (FM) severity, and QoL. Materials and methods: While the FM group consisted of 113 (74%) patients, the control group consisted of 40 (26%) individuals. FM symptom severity, ADHD symptom severity, and QoL were evaluated using the fibromyalgia impact questionnaire (FIQ), adult ADHD self-report scale (ASRS), and World Health Organization quality of life scale-brief version (WHOQOL-BREF), respectively. Results: It was found that the FM group had significantly higher scores on the ASRS than the control group (p < 0.05). There was a significant difference in FIQ scores and three WHOQOL-BREF domain scores between the FM alone and comorbid FM/high probability of ADHD groups (p < 0.05). We found a negative correlation between ASRS total scores and all other scale scores (except for the social relationships domain score of the WHOQOL-BREF) and a positive correlation between ASRS total scores and FIQ scores in FM patients. ADHD scores would mediate the relationship between depression severity and QoL. Conclusions: Our findings indicated that the presence of ADHD symptoms was related to greater FM symptom severity and poorer QoL. Also, ADHD scores would mediate the relationship between depression severity and QoL.

Utilization Of Biotechnological Drugs In Rare Diseases Requiring The Use Of Off-Label Drugsin Children In Turkey, Neri̇man İpek Kirmizi, Volkan Aydin, Nari̇n Akici, Banu Bayar, Ahmet Akici

Turkish Journal of Medical Sciences

Background/aim: Pediatric patients, especially those with rare diseases, represent a population that has a high tendency towards offlabel drug use (OLDU) and needs a more careful practice of pharmacotherapy than in adults. We aimed to investigate biotechnological drug use in children with rare diseases requiring OLDU. Materials and methods: This retrospective study examined all single-diagnosed OLDU applications (n = 5792) for 4992 children (

Effects Of Intracerebroventricularly Administered Opioid Peptide Antagonistson Tissue Glycogen Levels In Rats After Exercise, Ayşe Şebnem İlhan, Şevi̇n Güney, Si̇bel Di̇ncer

Turkish Journal of Medical Sciences

Background/aim: Physical exercise is a state of physiological stress that requires adaptation of the organism to physical activity. Glycogen is an important and essential energy source for muscle contraction. Skeletal muscle and liver are two important glycogen stores, and the energy required to maintain exercise in rodents are provided by destruction of this glycogen depot. In this study, the effects of endogenous opioid peptide antagonism at the central nervous system level on tissue glycogen content after exhaustive exercise were investigated. Materials and methods: Rats had intracerebroventricularly (icv) received nonspecific opioid peptide receptor antagonist, naloxone (50 μ/10 μL in saline) and …

Role Of Frailty In Prediction Of Hospitalized Older Adult Patient's Outcomes: A Prospective Study, Maryam Chehrehgosha, Reza Fadaye Vatan, Mahtab Alizadeh Khoei, Farshad Sharifi, Reyhaneh Aminalroaya, Zahra Vahabi, Abolfazl Zendedel, Hamidreza Hekmat

Turkish Journal of Medical Sciences

Background/aim: Frailty is associated with an increased risk of negative short-term and long-term hospital outcomes. This study aimed to evaluate the role of frailty in predicting readmission, length of stay, and quality of life in the hospitalized older adults. Materials and methods: This observational study was conducted at Ziaiyan Hospital, Tehran, Iran. In total, 304 participants (65-85 years), were enrolled through the inclusion criteria from August to December 2019. The frailty index (FI) was assessed by the minimum data set-home care. Readmission was obtained through telephone interviews. The length of stay was gathered by the patient's hospital records, and the …

Evaluation Of Serum Neutrophil Gelatinase-Associated Lipocalin (Ngal), Asymmetricdimethylarginine (Adma) And Symmetric Dimethylarginine (Sdma) Levels, And Theirrelations With Disease Type And Activity In Inflammatory Bowel Diseases, Hüseyi̇n Korkmaz, Mehmet Asil, Tuncer Temel, Bahadir Öztürk, Levent Kebapcilar

Turkish Journal of Medical Sciences

Background/aim: Inflammatory bowel disease (IBD) mainly encompass two entities called ulcerative colitis (UC) and Crohn's disease (CD), both of which are chronic, progressive and, inflammatory conditions of the gastrointestinal tract. Various indicators and noninvasive markers have been sought and used in IBD patients to help assessing disease activity and treatment effectiveness although none of them are proven to yield definite results in full correlation with the clinical, endoscopic, and histopathological examinations. The aim of the current study was to investigate the relationship of serum neutrophil gelatinase-associated lipocalin (NGAL), asymmetric dimethylarginine (ADMA), and symmetric dimethylarginine (SDMA) levels with disease type and …

Exploring New Pltl Modalities, Forging New Alliances, Nadia Kennedy, Ariane Masuda

Publications and Research

This essay focuses on rethinking and reimagining elements of a PLTL program, and on the new modalities to meet challenges of online undergraduate mathematics courses and rising demands for flexible student support. It examines advantages and challenges as found in the Integrated PLTL and Virtual Peer-Led Mathematics Study Groups, including issues such as meeting protocols, and the selection and training of peer leaders. Finally, it discusses an alliance with the college’s mathematics education program, which allows the PLTL program to draw on senior prospective teachers to co-organize and facilitate virtual study groups supporting undergraduate mathematics courses.

Who Is The Holy Seed?: Purity And Identity In The Restoration Community, Edward Allen Jones Iii

Faculty Publications - George Fox Digital

Interpreters often note the way in which the phrase ‘holy seed’ links Isa. 6.13 and Ezra 9.2. However, few explore how these texts apply the phrase to different communities/groups of people in ancient Judah. In Isaiah, the holy seed is the remnant in the land following the exile, whereas in Ezra, those returning from Babylon take the mantel for themselves. This essay, then, proceeds in three phases: first, it considers the function of Isa. 6.13 within the context of Isaiah’s call narrative, which helps situate Isaiah’s reference to the holy seed. Second, the study turns to Ezra 9.2 and examines …

The Edges Are Bleeding: Constitutional Proxies And Imprisoned Trans Bodies In Edmo And Gibson, Jen L. Davison

Minnesota Journal of Law & Inequality

No abstract provided.

A Disability Studies Perspective On The Legal Boundaries Of Fat And Disability, Katie Warden

Minnesota Journal of Law & Inequality

No abstract provided.

A Call To Congress: A Constitutional Indian Child Welfare Act Is Not A Flawless Indian Child Welfare Act, Maci Burke

Minnesota Journal of Law & Inequality

No abstract provided.

Comics For Pediatric Oncology Patients And Families: Education And Empowerment, Natalie Johns

Calvert Undergraduate Research Awards

The major objective is to develop the first book of a boxed set series of comic vignettes that will serve as a clinical educational tool for pediatric patients with a recent cancer diagnosis and their caregivers. These comics are hypothesized to improve patient and family understanding of the disease, its treatment, side effects, and outcomes in an engaging and aesthetically pleasing way. The overall goals of this project are to reduce anxiety and increase health literacy in patients and their families while assisting the oncology team in providing optimal medical care, thus improving the overall quality of treatment. Comics aimed …

Addressing The Ecological Fallacy With Lagrangian Inference, Michael Schwob

Calvert Undergraduate Research Awards

Most epidemiologists elect to use statistical models that use population-level data to make inference on the spread of some virus or disease. This has become commonplace in the fields of epidemiology and biostatistics since most data used to construct and verify epidemic models are recorded at the population-level. Obtaining inference from a population-level model may be beneficial in studying the spread of disease in a homogeneous population, but the use of such models to describe a heterogeneous population results in inadequate inference. The inaccuracy of these models is further amplified when one tries to make individual-level inference from these population-level …

North Dakota's New Frontier: Unmanned Aircraft, Matthew D. Dunlevy

Theses and Dissertations

Unmanned Aircraft, or drones, represent a modern-day frontier, one that is, as yet, neither fully explored nor fully developed. The state of North Dakota has moved into the frontier and is deeply involved in its exploration and development. The state has invested tens of millions of dollars in the Unmanned Aircraft Systems (UAS) industry, an investment that has helped to attract tens of millions of additional dollars from military sources and from private business firms. The University of North Dakota’s John D. Odegard School of Aerospace Sciences, long-recognized as among the leading aviation schools in the nation, is at the …

Development Of Metal-Containing Nanoparticles For Chemical Analysis And Bioanalysis, Juan Han

Theses and Dissertations

Metal-containing nanoparticles (MCPs) have been applied in fields ranging from environmental monitoring to biomedicine. This breadth is due to the outstanding behavior of MCPs as catalysts and imaging agents, and the ease with which nanoparticle morphology, composition, and reactivity (such as agglomeration) can be controlled. The work described in this dissertation will have two fundamentally different foci that are both essential for further development of MCPs as tools for chemical and bioanalysis. The first focus is on particle-by-particle characterization MCPs and the second focus is on creation of new composite MCPs. A total of four projects are included in this …

Eating Disorder Symptoms On Female Collegiate-Level Athletes And Non-Athletes, Kennedy Victoria Kidd

Theses and Dissertations

In previous research, it found that the risk of developing an eating disorder (ED) is much higher in females compared to males (Dunca, Ziobrowski & Nicol, 2017; Raevuori, Keski-Rahkonen, & Hoek, 2014; Lewinsohn, Seeley, Moerk, & Striegel-Moore, 2002). Similarly, research has shown that the prevalence of EDs is much higher in female athletes compared to male athletes (Johnson, Powers, & Dick, 1999). Despite the risk of developing an ED being higher in females, research has not provided a strong understanding of the prevalence of EDs comparing female student-athletes and female student non-athletes. There is research that shows that athletes may …

Concentration-Streamflow Relationship In The Red River To North Near Grand Forks, North Dakota, Kabamba Nancy Ngoyi

Theses and Dissertations

For the last 15 years, the nutrient concentrations have fluctuated in both particulate and dis-solved forms. The increasing concentration of sulfate and chloride in the North Great Plain Basin impose threats to water quality in the Basin. During this spring snowmelt season of 2021, water samples were collected three times daily in the Red River at Grand Forks, North Dakota to de-velop a concentration streamflow relationship for sulfate, nitrate, chloride, and fluoride. The 2020-2021 winter was very dry as a result the snowmelt streamflow was very low, the rising limb period was short, but the streamflow increased rapidly from 75 …

Transcriptomic And Pharmacological Characterization Of A Murine Line Harboring An Antidepressant-Insensitive Serotonin Transporter, Meghan Alicia Rodriquez

Theses and Dissertations

Perinatal depression is a complex mood disorder often treated with Selective Serotonin Reuptake Inhibitor (SSRI) antidepressants, which block the serotonin transporter (SERT) and alter synaptic serotonin concentrations. The serotonergic system is highly plastic and serotonin regulates the growth and maturation of neurons and signaling systems from conception through end of life. Notably, interference with serotonin levels during an SSRI sensitive window (SSW) of development in humans and rodents has been linked to neurovegetative effects which increase susceptibility for the manifestation of anxiety- and depressive-like behaviors and can be persistent throughout life. We hypothesize the persistent behavioral perturbations resulting from acute …

Student-Athlete Motivation And Gender, Jessica Schanilec-Gowan

Theses and Dissertations

Billions of dollars are spent each year on athletic teams and the education of National Collegiate Athletic Association (NCAA) student-athletes. Successful athletic programs require teams that are excelling in the classroom and also within their sports. Stakeholders are continually searching for factors that impact the academic success of the student-athlete population. This study explored one of those factors: motivation. In this research, an ex post facto quantitative research format was utilized to determine if there were relationships among three subscales of Gaston’s (2002) Sports and Academics Questionnaire (SAMSAQ) and gender identity. More specifically, the three SAMSAQ subscales that were examined …

Role Of Schlafen 12 In Lung Adenocarcinoma And Triple Negative Breast Cancer, Sarmad Al-Marsoummi

Theses and Dissertations

Schlafens are a family of genes expressed in a wide range of mammals, including rodents and humans. Schlafens are grouped based on molecular structure and size into the short, intermediate, and long Schlafen families. Mice express all three families of Schlafens; in contrast, humans express only long and intermediate Schlafens. Schlafens have diverse functions, including cell proliferation, cell differentiation, immune cell growth and maturation, viral replication, cancer cell biology, and chemosensitivity. Our studies have focused on Schlafen 12 (SLFN12). SLFN12 is an intermediate Schlafen, it is expressed in humans but not in rodents, and is localized to the cytoplasm. SLFN12 …

Giving Birth On Foreign Soil: A Phenomenological Study Of Somali Women Giving Birth In North Dakota And Minnesota, Tracy Jo Enger

Theses and Dissertations

Health disparities continue to exist in minority populations in the United States. People ofcolor have a higher incidence of negative birth outcomes; and view their experiences with less satisfaction. The purpose of this study was to explore what Somali Muslim have women have experienced during their labor and delivery in Minnesota and North Dakota. This research was conducted to improve our understanding of the needs of Somali women during labor and delivery in order to provide nursing care that is culturally sensitive. Phenomenological data was collected from personal interviews with Somali women who had given birth in North Dakota and …

Developing Computer Aided Algorithms For Automatic Assessment Of Psoriasis Disease Severity Using Digital Images, Intisar Rizwan I Haque

Theses and Dissertations

The purpose of the research work was to develop image processing algorithms for automatic and objective assessment of psoriasis to aid in more effective management and treatment of patient symptoms. For this purpose, multiple classical machine learning-based unsupervised approaches are proposed which achieve a maximum average accuracy of ~94% on a dataset of 45 images of various resolutions. This accuracy improves performance by 14% in comparison to existing approaches reported in the literature on the same dataset of images. An alternative deep learning neural network-based approach was proposed that achieves an average accuracy of ~87% for the same set of …

An Investigation Of Endangered And Threatened Plants Using Phylogenomics, Phylogenetic Metrics, And Geography To Prevent Species Loss, Phyllis H. Pischl

Graduate Research Theses & Dissertations

The conservation of endangered and threatened plant species plays an integral part of preserving biodiversity. Loss of habitat is one of the main reasons that plants become endangered or threatened. In Illinois much of the native habitat has been lost to the conversion of industry, agriculture and urban areas. The goals of this dissertation are to 1) determine where endangered and threatened species are finding habitats in relation to land use, 2) produce a robust phylogeny of endangered and threatened species of grasses and apply phylogenetic diversity analysis to better understand the plight of these species, and 3) use climate …

"Sup Bro": Constructions And Perceptions Of Masculinity And Gender Identity Among Division Iii Student-Athlete Men, Mark Carbonara

Graduate Research Theses & Dissertations

Patriarchal systems of power, privilege, and oppression are reinforced by college men every day, but there are certain populations of college men who wield a stronger ability to influence change. Student-athlete men at NCAA Division III institutions are often viewed as “culture creators” on their campuses. Moreover, many of these programs reside at smaller institutions, where the impact of toxic masculinity has potential to be more concentrated. Student-athlete men are often seen as representing hegemonic forms of masculinity, therefore having influence in setting norms of what is expected of men on campus. This critical narrative inquiry study explored how participating …

The Effect Of Depression On Adolescent Deviant Behavior And The Mediating Effect Of Autonomy, Theresa Lee

University of the Pacific Theses and Dissertations

The purpose of this study was to synthesize the relations among the adolescent need for autonomy in decision making process, depression, and tendencies for deviant or risk-taking behaviors as adolescents. Background variables such as socio-economic status, sex, race, previous academic achievement, parent warmth and support, resistance to peer pressure were controlled for. Using the NICHD database set, multiple regression analyses revealed that adolescent autonomy was not correlated with adolescent depression, and earlier depression at sixth grade was not a significant mediator of the effect of earlier deviant behaviors at sixth grade on later adolescent deviant behaviors. More importantly, however, the …

Is There A Catholic Theology Of Masculinity?, Peter Holmes

Theses

In recent times Catholic theologians have begun to speak of a ‘feminine genius’. Yet relatively little attention given to the unique and positive contribution of masculinity and manhood to relationships, the Church and society. This thesis aims to answer the question, “Is there a corresponding ‘masculine genius?” It attempts to synthesise a specifically Catholic understanding of masculinity from the magisterial teaching of the Catholic Church, to determine a basis for development of the Catholic understanding of masculinity and to propose some lines of development for Catholic theology in this area.

Chapter One will establish the need for and purpose of …