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Intertext 2021 — Complete Issue

Intertext

No abstract provided.

Proximate Cause Explained: An Essay In Experimental Jurisprudence, Joshua Knobe, Scott J. Shapiro

University of Chicago Law Review

One of the oldest debates in American jurisprudence concerns the concept of “proximate cause.” According to so-called formalists, the legal concept of proximate cause is the same as the ordinary concept of “cause.” The legal question of whether a cause is proximate for the purposes of establishing tort liability, therefore, is an objective matter about the external world determinable by familiar descriptive inquiry. By contrast, legal realists think that issues of proximate causation are disguised normative questions about responsibility. As the realists William Prosser and W. Page Keeton put it, proximate cause is better called “responsible cause.”

Recent work in …

A Class Of One: Multiracial Individuals Under Equal Protection, Desirée D. Mitchell

University of Chicago Law Review

When it comes to recognizing multiracial individuals under the Equal Protection Clause, courts have fallen short. Only rarely do courts explicitly identify multiracial plaintiffs as just that—multiracial. Instead, the majority of courts revert to a “one-drop” rule in which they view plaintiffs as only one part of their self-identified racial composition. In doing so, the unique identities and experiences of multiracial individuals remain unaddressed. This Comment builds off previous scholarship by arguing that courts can and should do better at recognizing multiracial plaintiffs in equal protection cases by using a “class-of-one” framework. Under that doctrine, the Supreme Court has held …

Artificially Intelligent Persons, Nadia Banteka

Scholarly Publications

Artificial Intelligence (AI) entities seriously challenge traditional legal frameworks for attribution and liability because they operate at an increasing distance from their developers and owners, resulting in accountability gaps. Consider a scenario in which a self-driving car causes injury or even death to a human. Who do we hold accountable? We have no clear answer as to who can be sued or prosecuted because we lack a comprehensive legal understanding of AI entities. Many scholars propose as a solution to the accountability problem attaching liability to the direct source of the harm, the Al entity itself, by first granting it …

Digest Of The Philadelphia College Of Osteopathic Medicine, Philadelphia College Of Osteopathic Medicine

PCOM Digest 2020s

The (2021 No. 2) issue of the Digest of the Philadelphia College of Osteopathic Medicine includes the following articles:

• Updates
• Advancing Alumni
• Reimagining Public Health: Pivoting from Pandemic Response to Future Prevention
• Rethinking Burnout, Mental Health and Well-being
• A Pandemic Within a Pandemic: Addressing Marginalized and Minoritized Communities to Foster Recovery
• Class Notes

Addictive Technology And Its Implications For Antitrust Enforcement, James Niels Rosenquist, Fiona M. Scott Morton, Samuel N. Weinstein

North Carolina Law Review

No abstract provided.

Losing Ground: How The Supreme Court's Use Of Easement Law In U.S. Forest Service V. Cowpasture River Preservation Ass'n Thwarts Environmental Justice, William W. Metcalf

North Carolina Law Review

No abstract provided.

The Ethiopian Staple Food Crop Enset (Ensete Ventricosum) Assessed For The First Time For Resistance Against The Root-Lesion Nematode Pratylenchus Goodeyi, Selamawit A. Kidane, Beira H. Meressa, Solveig Haukeland, Anne Kathrine Hvoslef-Eide, Danny L. Coyne

All Peer-Reviewed Publications

Summary – Pratylenchus goodeyi appears to be the most prevalent nematode pest of enset in Ethiopia, where it can occur in extremely high densities. However, the damage to yield or how different enset cultivars react to the nematode has yet to be determined. The current study therefore sought to establish a first assessment of these reactions by enset to P. goodeyi infection. Determining pest-resistant cultivars is an important task in developing management strategies. Our study evaluated nine enset cultivars to establish host response and identify potential sources of resistance. In addition, the pathogenicity of P. goodeyi was assessed on three …

Naturally Occurring Compounds With Larvicidal Activity Against Malaria Mosquitoes, Trizah K. Milugo, David P. Tchouassi, Reginald A. Kavishe, Rhoel R. Dinglasan, Baldwyn Torto

All Peer-Reviewed Publications

Female Anopheles mosquitoes transmit Plasmodium parasites that cause human malaria. Currently, vector control is the most widely deployed approach to reduce mosquito population and hence disease transmission. This relies on use of insecticide-based interventions including Long-lasting Insecticide-treated Nets (LLINs) and Indoor Residual Spraying (IRS) where scale-up has contributed to a dramatic decline in malaria deaths and morbidity over the past decade. Challenges to their effective use include the emergence and spread of insecticide resistance by malaria vector populations coupled with the inability to curb outdoor transmission. Under these situations, use of larvicides through larval source management (LSM) can complement these …

Trapping, Identification And Rearing Of Edible Palm Weevils In Kenya And Uganda, J. P. Egonyu, K. J. Gitonga, F. M. Khamis, R. S. Copeland, P. Finyange, R. Odhiambo, G. Ddamulira, C. M. Tanga, S. Subramanian

All Peer-Reviewed Publications

Palm weevils, Rhynchophorus spp. (Coleoptera: Curculionidae) double as devastating invasive pests of palms, and delicacies in many communities. This study evaluated ethyl acetate and 3-methyl-octan-4-ol for trapping palm weevils from coconut, oil and raffia palms in Kenya and Uganda; taking into account the distance of traps on oil palm from a forest or raffia palm. Eggs from the weevils from different locations were incubated and their larvae reared on sugarcane under laboratory conditions. All the 285 weevils collected were identified by morphological and molecular techniques as Rhynchophorus phoenicis, and the catch was female-biased. 3-methyl-octan-4-ol attracted more weevils than ethyl acetate. …

The Out-Of-Classroom Engagement Experiences Of First-Generation College Students That Impact Persistence, Sherolyn Hopkins, Jamie L. Workman, William Truby

Journal of Higher Education & Student Affairs

This article is the result of research conducted with first-generation upper-class college students enrolled at a comprehensive university in Georgia. The researcher sought to answer the following research question: How do first-generation college students perceive the impact of out-of-classroom engagement experiences on persistence?

Participants were selected based on a purposeful sampling technique. The researcher utilized a qualitative interpretive approach and collected data via individual interviews and a focus group. The researcher was able to organize the rich data into themes. The article concludes with implications for student affairs professionals and future research on first-generation college students.

Keywords: first-generation college students, …

Cannibalism, Oviposition And Egg Development In The Edible Long-Horned Grasshopper, Ruspolia Differens (Orthoptera: Tettigoniidae) Under Laboratory Conditions, J. P. Egonyu, M. M. Miti, C. M. Tanga, A. Leonard, S. Subramanian

All Peer-Reviewed Publications

Reliance on seasonal wild harvests of the edible long-horned grasshopper Ruspolia differens (Serville) (Orthoptera: Tettigoniidae) needs to be broken through developing efficient mass rearing protocols. This study aimed at boosting productivity of laboratory colonies of R. differens through understanding ways of minimising cannibalism, selecting suitable oviposition substrates and enhancing egg development and hatchability. Firstly, we investigated the extent of cannibalism in a colony of R. differens relative to total mortality, sex, diurnality, growth stage, body parts eaten and visual barriers (presence/absence of cardboard egg trays). R. differens cadavers recovered from cages with/without the egg trays were scored for cause of …

Tsetse Blood-Meal Sources, Endosymbionts And Trypanosome-Associations In The Maasai Mara National Reserve, A Wildlife-Human-Livestock Interface, Edward Edmond Makhulu, Jandouwe Villinger, Vincent Owino Adunga, Maamun M. Jeneby, Edwin Murungi Kimathi, Enock Mararo, Joseph Wang’Ang’A Oundo, Ali Abdulahi Musa, Lillian Wambua

All Peer-Reviewed Publications

African trypanosomiasis (AT) is a neglected disease of both humans and animals caused by Trypanosoma parasites, which are transmitted by obligate hematophagous tsetse flies (Glossina spp.). Knowledge on tsetse fly vertebrate hosts and the influence of tsetse endo-symbionts on trypanosome presence, especially in wildlife-human-livestock interfaces, is limited. We identified tsetse species, their blood-meal sources, and correlations between endosymbionts and trypanosome presence in tsetse flies from the trypanosome-endemic Maasai Mara National Reserve (MMNR) in Kenya. Among 1167 tsetse flies (1136 Glossina pallidipes, 31 Glossina swynnertoni) collected from 10 sampling sites, 28 (2.4%) were positive by PCR for trypanosome DNA, most (17/28) …

Being In Centro: The Anthropology Of Schelling's Human Freedom, Michael Vater

Philosophy Faculty Research and Publications

Schelling presents the 1809 freedom essay as the idealistic flowering of a vision of system he always held. He is not disingenuous but somewhat perplexing in claiming that the system always was complete in nuce, even though not expounded completely. Tilliette captured the ambiguity nicely in designating Schelling’s oeuvre «une philosophie en devenir». This mid-career essay must be read backwards to the earliest essays republished with it—especially to their views of willing, freedom, and moral responsibility—and simultaneously forward to the late philosophy’s analysis of God’s freedom as freedom from being, even necessary being. I locate Freedom’s …

Introduction: What Matters For Black Workers After 2020?, Michael Z. Green

Faculty Scholarship

This paper operates as the Introduction to a Symposium that resulted from a Call for Papers discussing the topic of "What Matters for Black Workers after 2020?" to be published in the 25th volume of the Employee Rights and Employment Policy Journal for 2021. This paper briefly discusses the papers in that Symposium publication authored by Jamillah Bowman Williams, Michael Duff, and Henry Chambers that address this topic. I thank Noah Zatz, Marty Malin, Michael Oswalt, Marcia McCormick, and Tristan Kirvan for their dedicated efforts, feedback, and encouragement in completing this Symposium issue for the journal on this very important …

Risk Factors For Poor Outcomes Among Patients With Extensively Drug-Resistant Tuberculosis (Xdr-Tb): A Scoping Review., Karan Varshney, Beverly Anaele, Matthew Molaei, Rosemary Frasso, Vittorio Maio

College of Population Health Faculty Papers

In recent years, there has been an upsurge in cases of drug-resistant TB, and strains of TB resistant to all forms of treatment have begun to emerge; the highest level of resistance is classified as extensively drug-resistant tuberculosis (XDR-TB). There is an urgent need to prevent poor outcomes (death/default/failed treatment) of XDR-TB, and knowing the risk factors can inform such efforts. The objective of this scoping review was to therefore identify risk factors for poor outcomes among XDR-TB patients. We searched three scientific databases, PubMed, Scopus, and ProQuest, and identified 25 articles that examined relevant risk factors. Across the included …

Being Needed, Cared For, And Present: Belonging And Disability In The Seventh-Day Adventist Church In North America, Shannon M. Trecartin, Mikelle Wile, Terrance P. Trecartin, Petr Činčala

Faculty Publications

Many Christian churches seek to be places of belonging, yet present barriers to inclusion. The present research focuses on disability and belonging in members of the Seventh-day Adventist (SDA) Church in North America. Data from the SDA Global Church Survey (2017–2018) were used to measure attendance, perceived care, and sense of being needed. Results: Differences in attendance, leadership, and “feeling cared for” were observed. The findings of this study suggest that the SDA Church has had both successes and room for growth in terms of creating opportunities for belonging among people with disabilities. Implications for other denominations are also discussed.

Transparency Of Regulatory Data Across The European Medicines Agency, Health Canada, And Us Food And Drug Administration, Alexander C. Egilman, Amy Kapczynski, Margaret E. Mccarthy, Anita T. Luxkaranayagam, Christopher J. Morten, Matthew Herder, Joshua D. Wallach, Joseph S. Ross

Articles, Book Chapters, & Popular Press

Based on an analysis of relevant laws and policies, regulator data portals, and information requests, we find that clinical data, including clinical study reports, submitted to the European Medicines Agency and Health Canada to support approval of medicines are routinely made publicly available.

From Sandbox To Pandemic: Agile Reform Of Canadian Drug Regulation, Ipek Eren Vural, Matthew Herder, Janice E. Graham

Articles, Book Chapters, & Popular Press

Public health urgency for emerging COVID-19 treatments and vaccines challenges regulators worldwide to ensure safety and efficacy while expediting approval. In Canada, legislative amendments by 2019 Om- nibus Bill C-97 created a new "agile" licensing framework known as the "Advanced Therapeutic Pathway" (ATPathway) and modernized the regulation of clinical trials of drugs, vaccines, and medical devices. Bill C-97′s amendments are worthy of attention in Canada and globally, as health product regulation bends to COVID-19. The amendments follow reforms elsewhere to accommodate health product innovation, how- ever, the Canadian ATPathway is broader and more flexible than its counterparts in other jurisdictions. …

Exploring The Food And Drug Administration’S Review And Approval Of Entresto (Sacubitril/Valsartan), Ashley Eadie, Keith Brunt, Matthew Herder

Articles, Book Chapters, & Popular Press

Federal regulatory agencies such as the United States Food and Drug Administration review pharmacological evidence to ensure the safety and efficacy of new and repurposed pharmaceuticals prior to market approval. The discussions, disagreements and procedural decisions contained within such reviews offer unique insight into a pharmaceutical's strengths, weaknesses and opportunities, yet are often overlooked as a significant source of pharmacological information for research and development. To highlight the value of such resources, we present a case study on Entresto, a first-in-class angiotensin receptor-neprilysin inhibitor for the treatment of heart failure with reduced ejection fraction, and explore the regulatory rationale underlying …

In The Name Of Public Health: Misoprostol And The New Criminalization Of Abortion In Brazil, Mariana Prandini Assis, Joanna Erdman

Articles, Book Chapters, & Popular Press

This article explores the criminal regulation of misoprostol as a controlled drug in Brazil as a new form of abortion criminalization. A qualitative analysis of Brazilian case law shows how the courts use a public health rhetoric of unsafe abortion to criminalize the distribution of misoprostol in the informal sector. Rather than an invention of the local bench, this judicial rhetoric reflects global public health discourse and policy on unsafe abortion and the double life of misoprostol as both an essential medicine and a controlled drug. In contrast to previous studies, the article shows that abortion criminalization is not the …

A Short History Of Recycling At Csb, Peggy L. Roske

Archives History Lessons

No abstract provided.

Assessing The Significance Of Substrate Color And Temperature On Balanus Glandula Growth And Survivorship, Nhi Phan

CMC Senior Theses

The body temperatures of intertidal species are strongly dependent on the temperature of their external environment. This study sought to understand the impact of a substrate’s color and subsequent temperature on Balanus glandula in order to predict the potential effects of warming temperatures from climate change on intertidal species. Barnacles were allowed to settle and grow on three differently colored plates and were photographically monitored over the course of eleven weeks. Settlement and survivorship were recorded on-site, while growth was tracked utilizing digital imaging software. It was hypothesized that barnacles on peach plates would perform the best since the ambient …

Climate Change In Fiction: The Evolution And Challenges Of Environmental Apocalyptic Literature, Lauren Gode

CMC Senior Theses

This thesis examines the several aspects and variations of environmental apocalyptic literature, and its potential ability to mobilize action against the imminent threat of global climate change. It delves into the intersection between climate research and fiction, as well as the rhetorical techniques used in works such as The Death of Grass by John Christopher, The Drowned World by J.G. Ballard, Oryx and Crake by Margaret Atwood, and The Road by Cormac McCarthy, and covers the complementarity between climate fiction and works of non-fiction such as The Great Derangement by Amitav Ghosh. Finally, this thesis will assess the effectiveness of …

The Motherhood Wage Penalty: New Evidence On Long-Run Effects And Group Heterogeneity, Vera Kratz

CMC Senior Theses

This paper seeks to establish the magnitude of the long-run motherhood wage penalty. Using data from the 1997 National Longitudinal Survey of Youth, I examine the difference between the real hourly wages of mothers and non-mothers in the long run. By comparing mothers to not-yet-mothers as well as never-mothers, I am able to better isolate the true wage penalty mothers face. My findings indicate that 21 to 25 years after the birth of their first child, mothers face a 31.75 percentage point wage penalty compared to non-mothers. In addition, I examine differences in the wage penalties of mothers by marital …

More Than A Myth: The Benefits Of Incorporating Holistic Healing Methods From Native American And Mexican Cultures To Approach Opioid Use Disorder (Oud) Treatment, Juliana Favela

CMC Senior Theses

Opioid Use Disorder (OUD) is a substance use disorder that characterizes a dependence on and an addiction to opioids. Opioids attack the prefrontal cortex, the dopaminergic reward system, and the hypothalamic-pituitary-adrenal (HPA) axis which is responsible for the body’s stress response. Opioids constantly shift one’s “set point” to the point where normal actions that cause joy and excitement no longer cause those feelings, resulting in craving and dependence. The opioid epidemic is currently ravaging the United States and has disproportionately affected Native American populations specifically in the rural areas (Tipps, et.al, 2018). The current methods for addressing OUD include medicine …

Environmental Controls On The Spatial Distribution Of Greenfin Darters And Biodiversity In The Blue Ridge Mountains, Dri Tattersfield

CMC Senior Theses

Disproportionate concentrations of biodiversity in mountains worldwide suggest linkages between geologic processes and biodiversity that are not yet well understood. The Tennessee River Basin in the Blue Ridge Mountains of the southeastern U.S. is a global hotspot for freshwater fish biodiversity. To investigate drivers of biodiversity in the Tennessee River Basin, and explore links to geologic processes, I study the Greenfin Darter (Nothonotus chlorobranchius), a small fish endemic to the upper Tennessee River Basin. I use generalized linear models (GLMs) to evaluate the influence of topography, lithology, climate and land use on the distribution of the Greenfin Darter, …

Using Nmr Spectroscopy And Computational Chemistry To Confirm The Structure Of Novel Antibiotic Nocamycin O, Stephanie Lewis

CMC Senior Theses

In recent years, many medically promising antibiotics have been discovered in nature, especially in insect-microbe symbioses. One of the better-studied examples of this kind of defensive relationship is that of fungus-growing ants and the antibiotic-producing Actinobacteria. These bacteria produce several defensive chemicals with myriad uses, including one antibiotic that inhibits the growth of several bacterial strains, including other Actinobacteria. This antibiotic (known as nocamycin O) is a promising candidate for medicinal use due to its similarities to bacterial RNA polymerase inhibitors tirandamycin and streptolydigin, which inhibit several human pathogens. The determination of the structure of nocamycin O will be an …

Understanding The Epigenetic Role Of 8-Oxoguanine And Ogg1 In Non-Small Cell Lung Cancer, Kyrellos Ibrahim

CMC Senior Theses

Oxidative damage to the genome can form 8-oxoguanine (oxoG), a premutagenic lesion suggested to play an epigenetic role in the regulation of various cellular pathways. Alongside oxoG in this regulation is the 8-oxoguanine DNA glycosylase (OGG1), which primarily functions to repair oxoG damage via base excision repair, but is also implicated in recruiting NFκB and impacting gene expression associated with cancer growth. This proposal aims to build genome-wide maps of oxoG occupancy, and indirectly OGG1 localization, in healthy lung cells and in non-small cell lung cancer adenocarcinoma cells in order to identify regulatory regions in the genome at which oxoG …

Viability Of Physiologically Timed Relaxation Interventions In Children With Asd, Nicholas Mendez

CMC Senior Theses

Autism Spectrum Disorder (ASD) is an increasingly common developmental disorder that changes how people experience the world and affects individuals’ social interactions and often leads to many adverse behaviors. Current literature dictates that a primary contributor to these adverse behaviors is that those with ASD have difficulty determining their own emotional states and determining the physiological signals that their body sends them. A study by Dr. Sarabadani et al. determined that it was possible to monitor the physiology of an individual with ASD and correlate certain signals to emotions, such as stress. These findings indicate the feasibility of establishing a …