Digital Commons Network^™

Teaching Mission In A Technological World, Robert Alden Danielson

Academic Books

No abstract provided.

Environmental Toxicant Trichloroethylene (Tce) Impacts Macrophage Function, Emily Schellenboom, Eleanor Scheeres, Ethan Houskamp, Rita Loch − Caruso, Sean Harris, Erica Boldenow

Summer Research

• Trichloroethylene (TCE) is an industrial solvent commonly used as a metal degreaser which accumulates as a toxicant in water and soil1
• There is little known about how environmental toxicants and infectious diseases (such as Group B Streptococcus) interact in pregnant women2
• Cytokines IL-1β, IL-6, IL-8 and TNF-α are proinflammatory cytokines important to immune function2
• Previous studies have shown that DCVC, a metabolite of TCE, has immunosuppressive effects3
• This summer we sought to discover a more comprehensive picture of DCVC’s effects on immunosuppression in macrophage-like cells

Common Data Set, 2020-2021, Office Of Institutional Research, Bridgewater State University, Bridgewater State University

Common Data Sets

No abstract provided.

Breastfeeding, Race And Mutual Aid, Tonya L. Brito, Sofia Jonas

California Western Law Review

No abstract provided.

Author Response: Skimmed Revisited, Andrea Freeman

California Western Law Review

No abstract provided.

Propranolol Sensitizes Vascular Sarcoma Cells To Doxorubicin By Altering Lysosomal Drug Sequestration And Drug Efflux, Jhuma Saha, Jong Hyuk Kim, Clarissa N. Amaya, Caleb M. Witcher, Ali Khammanivong, Derek M. Korpela, David R. Brown, Josephine Taylor, Brad A. Bryan, Erin B. Dickerson

Faculty Publications

Angiosarcoma is a rare cancer of blood vessel–forming cells with a high patient mortality and few treatment options. Although chemotherapy often produces initial clinical responses, outcomes remain poor, largely due to the development of drug resistance. We previously identified a subset of doxorubicin-resistant cells in human angiosarcoma and canine hemangiosarcoma cell lines that exhibit high lysosomal accumulation of doxorubicin. Hydrophobic, weak base chemotherapeutics, like doxorubicin, are known to sequester within lysosomes, promoting resistance by limiting drug accessibility to cellular targets. Drug synergy between the beta adrenergic receptor (β-AR) antagonist, propranolol, and multiple chemotherapeutics has been documented in vitro, and …

Listening To The Transgender Child’S Voice: Navigating Parent-Child Conflicts Regarding Gender-Affirming Care, Halle Paredes

Philosophy Honors Papers

No abstract provided.

Graduate Catalog 2021-2022, Southwestern Oklahoma State University

Graduate Catalogs

The 2021-2022 SWOSU Graduate Catalog.

Magnetic Resonance And Ct Imaging Biomarkers For Prediction Of Acute And Chronic Radiation-Induced Xerostomia, Anastasia Katsavochristou, Dimitrios Koumoulis

Oral Health Practice Faculty Publications

Xerostomia is a common adverse effect of radiation therapy at the head and neck area. Radiation-induced xerostomia can be severe and detrimental for the quality of life. Clinicians and radiologists have focused on the prevention of xerostomia as feasible, which has been significantly improved in the recent decades with the use of the contemporary radiation technology. However, radiation-induced xerostomia still remains one of the most devastating side effects of radiation therapy. Clinical risk factors have been identified, but the variation of its incidence and presentation has turned the focus on the investigation of parameters that would be able to predict …

The House Of Yisrael Cincinnati: How Normalized Institutional Violence Can Produce A Culture Of Unorthodox Resistance 1963 To 2021, Sabyl M. Willis

Browse all Theses and Dissertations

This study examines the racial, socio-economic, and political factors that shaped The House of Yisrael, a Black Nationalist community in Cincinnati, Ohio. The members of this community structure their lives following the Black Hebrew Israelite ideology sharing the core beliefs that Black people are the "true" descendants of the ancient Israelites of the biblical narrative. Therefore, as Israelites, Black people should follow the Torah as a guideline for daily life. Because they are the "chosen people," God will judge those who have oppressed them. This ideology, which began in the U.S. during the nineteenth century, has recently been growing more …

The F-Box Protein Fbw7 Negatively Regulates The Stability Of Erk3 Protein, Nicole Walters

Browse all Theses and Dissertations

Extracellular signal-regulated kinase 3 (ERK3) is a member of the atypical mitogen-activated protein kinase (MAPK) subfamily, whose members have been shown to play important roles in a number of cellular processes including proliferation, differentiation, migration, and apoptosis. While signals regulating ERK3 kinase activity remain unclear, ERK3 is known to be an unstable protein with function tightly regulated via ubiquitination and proteasomal turnover. The deubiquitinating enzyme USP20 has been shown to regulate ERK3 by stabilizing the kinase, but presently, no destabilizing ubiquitin ligases have been identified. The SKP1-CUL1-F-box protein (SCF) E3 ligases are a subfamily of ubiquitin E3 ligases composed of …

Icipe Annual Report 2021, International Centre Of Insect Physiology And Ecology (Icipe)

icipe Annual Reports

No abstract provided.

Big Data Analysis Of Nanoscience Bibliometrics, Patent, And Funding Data (2000-2019), Yuliang Zhao, Zhixiang Wei, Qing Dai, Hongwei Dong, Hongjun Xiao, Shuxian Wu, Xingxing He, Beverley Mitchell, Thomas A. Collins, Sarah Huggett, John Van Orden, Christiane Barranguet, Basak Candemir

Public Reports

Given the strategic significance of Nanoscience and nanotechnology, it is essential to evaluate and predict its developmental trends. This report is based on the largest abstract and citation database of peer-reviewed literature, Elsevier's Scopus, along with the research evaluation platform SciVal. The funding and patent analysis data for the report is from Funding Institutional and PatentSight, respectively. This report provides an evaluation of Nanoscience's scientific output, role, contribution, and impact through bibliometric analysis, combined with big data indicators of Nanoscience scientific results and patents from 2000 to 2019.

Data And Insights On International Science, Technology, And Innovation--Comparative Research Report Of 20 Global Cities, 2016-2020, Wang Qian, Wang Yang, Ruan Shu, Liu Meihua, Xingxing He, Dennis Yu, Başak Candemir Phd, Yingying Zhou Phd, Mph, Beverley Mitchell, Bamini Jayabalasingham Phd, Anders Karlsson Phd

Public Reports

This report, prepared by Elsevier in collaboration with the Administrative Center of Shanghai R&D Public Service Platforms, presents some key science, technology, and innovation indicators for 20 global cities. It is based on an earlier local report launched by the Center, which focused on the 2014--2018 period. To reflect the latest patterns and trends, Elsevier updated all the bibliometric analysis using data from 2016--2020 1 and used an updated methodology for the definition of cities. The analysis of patenting activities, which was conducted by the Center, was not updated

South Korea: A Technological Powerhouse Strengthening Its Research And Innovation Footprint, Basak Candemir Phd, Weiwei Cheng, Jörg Hellwig Phd, Erin Hill-Parks, Dana Jang, Anders Karlsson Phd, Donghyun Kim, Sohyeong Kim, Sumeet Rohatgi, Lu Zhao

Public Reports

Systematic investment in research and development has moved South Korea from an innovation follower to an innovation leader.

This report from Elsevier in collaboration with the National Research Foundation of Korea (NRF) presents some key indicators around the South Korean research and innovation ecosystem, with comparator countries being the United States, the United Kingdom, Japan, Germany, and China. The main study period of the report is 2015–2019.

Our focus in the report is on academic research, its volume and scholarly impact, as well as on focus topic areas and collaboration networks, both national and international. With three quarters of R&D …

2020-2021 Annual Report, Library Services

Annual Reports

No abstract provided.

The Effect Of School Return During The Covid-19 Pandemic On Children’S Physical And Mental Health, Kaitlynn Craig

Mahurin Honors College Capstone Experience/Thesis Projects

Flashback to midnight on January 1st, 2020. It was New Year’s Day, the beginning of a new decade. Many were filled with excitement and hope to make this year the best one yet. Little did they know that their entire world would be turned upside down a short two months later with a worldwide pandemic, the coronavirus. COVID-19 has affected people in many ways. Some lost their jobs, others struggled to maintain their education virtually, and unfortunately, too many lost their lives. As a nursing student, fear grew while imagining the role of becoming one of the frontline workers battling …

Academic Performance, Anxiety, And Feelings Of Classroom Displacement In College Students Amidst The Covid-19 Pandemic., Myron Eusebio

Psychology | Senior Theses

Amidst the Coronavirus pandemic, universities are beginning to shift primarily to online courses and hybrid courses. This presents a potential issue because it disrupts the traditional learning experience that students expect from attending an academic institution. The pandemic and sudden disruption of traditional classroom learning may cause adverse changes in a student’s anxiety levels and academic performance. Research has shown that online courses often require students to have lower anxiety levels to perform well academically, which highlights a problematic relationship in students feeling higher levels of anxiety in online classes. (Solimeno et., 2007). The goal of this study is to …

The Effects Of Rolipram, A Selective Phosphodiesterase Inhibitor, On Immortalized Schwann Cell Proliferation, Akap95 And Cyclin D3 Expression, Kyle P. Kenney, Mary Pistack, Angela Asirvatham

Student Research Poster Presentations 2021

Schwann cells are a vital component of the Peripheral Nervous System and aid in the repair of axons following injury. The regulation of Schwann cell growth in vitro is facilitated by heregulin, a neuron-secreted growth factor, and an unknown mitogen that activates the cyclic adenosine monophosphate (cAMP) pathway. The abundance of intracellular cAMP is regulated by a family of enzymes called phosphodiesterases (PDEs). PDE inhibitors such as rolipram have therapeutic potential in various disorders and function by increasing the levels of intracellular cAMP. A-Kinase anchoring proteins (AKAPs), a family of scaffolding proteins that belong to the cAMP/Protein Kinase A (PKA) …

Analysis Of Methods To Measure Heart Rate In Mytilus Edulis, Kristin Pinho

Student Research Poster Presentations 2021

Non-invasive research will be performed to limit the additional stress from equipment and focus on the harmful effects that polluted run-off water has on mussels’ heart rates. The chemical that will be introduced to the laboratory environment will be weed killer. This research will simulate how water pollution affects different aquatic species and how that ultimately leads to environmental changes, while evaluating the most effective methods to conduct this research.

Investigating The Role Of Schizophrenia-Associated Gene Expression In The Developing Human Brain Using Machine Learning, Katie Kelly

Other resources

Schizophrenia is a debilitating condition that affects 1% of the population, causes significant hardship and though there are treatments available they are characterised by several limitations. It is a complex mental disorder where some individuals show mild subclinical cognitive symptoms before psychosis onset in adolescence. The treatments available only target a portion of the symptoms and although extensive research has been conducted, a comprehensive understanding of the nature of schizophrenia remains elusive. Unlike other neurodevelopmental disorders, schizophrenia symptoms do not typically present themselves until adolescence. This study aimed to discover gene co-expression networks at multiple developmental stages to identify candidate …

Hurricane Irma Induces Divergent Behavioral And Hormonal Impacts On An Urban And Forest Population Of Invasive Anolis Lizards: Evidence For An Urban Resilience Hypothesis, Haralambos Fokidis, Taylor Brock

Faculty Publications

Hurricanes can have both profound short-term effects on animal populations and serve as long-term drivers of evolutionary change. Animals inhabiting varying habitats may differ in their response to hurricane impacts. Increasing evidence sug- gests that animals from urban areas exhibit different behavioral and physiological traits compared to rural counterparts, in- cluding attenuated hormonal stress responses and a lowered propensity for flight behavior. A unique opportunity was pre- sented when Hurricane Irma hit Florida on 10 September 2017 and interrupted a study of invasive brown anoles (Anolis sagrei) at an urban and a forest. Using data collected before and after Hurricane …

Disproportionality Of Women In Stem Careers, Rachel J. Lanquist

All Electronic Theses and Dissertations

Despite inclusion efforts for women to be equally represented across all disciplines and at all career levels in science, technology, engineering, and mathematics (STEM), there remains a significant gap between males and females within the job market. The purpose of this cross-sectional, quantitative study was to examine how gender differences in mathematics and science are related to identity and self-efficacy and students’ comparison of STEM subject competency. The secondary focus was to investigate the influence that STEM self-efficacy and STEM identity have on enrolling in advanced STEM-related classes. This research used secondary data from the follow-up High School Longitudinal Study …

Examining Dbt Day Treatment In Treating Mood Dysregulation Expectancy And Anxiety In Women Diagnosed With Eating Disorders, Shannon O'Mara, Leah Vandine, Anthony M. Tarescavage, Denise Ben-Porath

2021 Faculty Bibliography

Eating disorders (EDs), particularly anorexia nervosa (AN) and bulimia nervosa (BN), are characterized by emotional and behavioral disturbances in eating patterns and body image that result in significant distress and functional impairment (as reported by APA, (APA dictionary of psychology, American Psychological Association, Washington, DC, 2015)). Ben-Porath and colleagues (Journal of Contemporary Psychotherapy 40:115-123, 2010) have researched the effectiveness of dialectical behavioral therapy (DBT) day treatment program in reducing negative mood regulation and anxiety among women diagnosed with AN, BN, and eating disorder not otherwise specified (EDNOS). The current study extended past research on the effectiveness of DBT day treatment …

Metagenome Sequencing To Explore Phylogenomics Of Terrestrial Cyanobacteria, Ryan D. Ward, Jason E. Stajich, Jeffrey R. Johansen, Marcel Huntemann, Alicia Clum, Brian Foster, Bryce Foster, Simon Roux, Krishnaveni Palaniappan, Neha Varghese, Supratim Mukherjee, Tbk Reddy, Chirs Daum, Alex Copeland, Ima Chen, Natalia N. Ivanova, Nikos C. Kyrpides, Nicole Shapiro, Emiley A. Eloe-Fadrosh, Nicole Pietrasiak

2021 Faculty Bibliography

Cyanobacteria are ubiquitous microorganisms with crucial ecosystem functions, yet most knowledge of their biology relates to aquatic taxa. We have constructed metagenomes for 50 taxonomically well-characterized terrestrial cyanobacterial cultures. These data will support phylogenomic studies of evolutionary relationships and gene content among these unique algae and their aquatic relatives.

Trichotorquatus Gen. Nov. - A New Genus Of Soil Cyanobacteria Discovered From American Drylands, Nicole Pietrasiak, Sharon Reeve, Karina Osorio-Santos, David A. Lipson, Jeffrey R. Johansen

2021 Faculty Bibliography

Cyanobacteria are crucial ecosystem components in dryland soils. Advances in describing a–level taxonomy are needed to understand what drives their abundance and distribution. We describe Trichotorquatus gen. nov. (Oculatellaceae, Synechococcales, Cyanobacteria) based on four new species isolated from dryland soils including the coastal sage scrub near San Diego, California (USA), the Mojave and Colorado Deserts with sites at Joshua Tree National Park and Mojave National Preserve, California (USA), and the Atacama Desert (Chile). The genus is morphologically characterized by having thin trichomes (<4.5 lm wide), cells both shorter and longer than wide, rarely occurring single and double false branching, necridia appearing singly or in rows, and sheaths with a distinctive collar-like fraying and widening mid-filament, the feature for which the genus is named. The genus is morphologically nearly identical with Leptolyngbya sensu stricto but is phylogenetically quite distant from that genus. It is consequently a cryptic genus that will likely be differentiated in future studies based on 16S rRNA sequence data. The type species, T. maritimus sp. nov. is morphologically distinct from the other three species, T. coquimbo sp. nov., T. andrei sp. nov. and T. ladouxae sp. nov. However, these latter three species are morphologically very close and are considered by the authors to be cryptic species. All species are separated phylogenetically based on sequence of the 16S-23S ITS region. Three distinct ribosomal operons were recovered from the genus, lending difficulty to recognizing further diversity in this morphologically cryptic genus.

Faculty Notes, John Carroll University

Faculty Notes - John Carroll University

Fall 2021, Volume 14, Issue 2

The Economics Of Biodiversity The Dasgupta Review Abridged Version, Sir Partha Dasgupta

Environmental Economics

In 2019, Her Majesty’s Treasury (UK) commissioned Sir Partha Dasgupta, an economist and Professor Emeritus at Cambridge University to produce an independent, global review on the Economics of Biodiversity. Sir Partha was assisted by a multi-disciplinary Advisory Panel that included representatives of public policy, science, economics and business. The Review argues that countries should de-emphasize GDP as an index of progress and instead should focus on a national Wealth measure that includes an accounting for Natural Capital. After World War II, when the world was very different from what it is now, Sir Partha argues the economic questions being faced …

Genes May Have A Big Influence On Vegetarianism, Harold Herzog

Herzog - Dietary Issues

A Dutch research project found that identical twins were more similar than fraternal twins in giving up meat. This suggests that one’s genetic make-up may play a role in whether one is a vegetarian or not. The genetic effect became less influential in males than in females as they grew older.

Review Of The Evidence Of Sentience In Cephalopod Molluscs And Decapod Crustaceans, Jonathan Birch, Charolotte Burn, Alexandra Schnell, Heather Browning, Andrew Crump

General - Animal Feeling

Birch and colleagues have developed an important and useful framework for evaluating the evidence for sentience – namely, the capacity to experience pain, distress and suffering, in cephalopod molluscs (cuttlefish, octopods and squid) and decapod crustaceans (including crabs, crayfish, lobsters, prawns, shrimps). Birch and colleagues develop eight criteria in their evaluation framework which are used to weigh the evidence from over 300 scientific publications. The report also investigates the potential welfare implications of current commercial practices on these species. The report concludes that cephalopods and decapod crustaceans are probably sentient.