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Duet Phonology And Syntax Of The Red-Crowned Parrots In South Texas, Abigail Pozulp

Theses and Dissertations

Bird behavioral interaction systems show a preference for temporal precision. This preference is exemplified in the way many species avoid masking of vocal signals. Antiphonal duetting in songbirds suggest that overlapping notes are a sign of poor temporal coordination which can signify a weak pairbond, a possible cue for conspecifics seeking to usurp territories or mates. However, parrots (Psittacidae) are accomplished yet understudied duetters in nature. I recorded antiphonal duets produced by a wild population of red-crowned parrots (Amazona viridigenalis) in Brownsville, Texas. Temporal and acoustic variation of signals was assessed within and across a sample of mated …

Development Of A Novel Strategy To Improve Checkpoint Immune Response In Pancreatic Cancer, Poornima Devi Shaji

Theses and Dissertations

Pancreatic Cancer is the 3rd lethal causing cancers in United States with a survival rate less than 5-7%. In advanced unresectable pancreatic cancer, treatment options are restrained to surgery because of its extreme aggressiveness. Immunotherapy, one of the current advanced treatments has shown promising response in other cancers. However, this therapy is limited in pancreatic cancer due to desmoplasia and fibrotic tumor microenvironment (TME).

Our superparamagnetic iron oxide nanoparticles (SPIONS) of curcumin (Curcuma longa, principal curcuminoid of turmeric) have potential ability to inhibit desmoplasia and tumor stroma with an increased bioavailability. This would soften up the tumors for …

The Impacts And In-Depth Study Of The Environmental Contaminant, Perfluorooctane Sulfonic Acid, And Its Interactions With Water, Karla Veronica Salazar

Theses and Dissertations

Perfluorooctanesulfonic acid (PFOS), similar to perfluorooctanoic acid (PFOA), is a synthetic chemical that has been classified as a persistent organic pollutant (POP) by the Stockholm Convention since 2009. Due to the wide previous usage, high stability, high bio-accumulative, and low degradative properties is the reason that PFOS has been found in several compartments of the environment including ocean water, ground water, air, and sediments. Due to the strong interactions generated by the sulfonic acid end, this compound has a tendency to stay in the environment for long periods of time and has proved to be difficult in the removal from …

Positive Well-Being And Satisfaction With Life: Variables Affecting The Quality Of Life Of People With Bipolar Disorder, Maria Del Trevino-Zuniga

Theses and Dissertations

Bipolar disorder (BD) is a highly prevalent and severe mental illness of significant public health importance. Characteristics of BD include dramatic shifts in mood, energy, and activity levels affecting a person's ability to carry out day-to-day tasks. These shifts in mood and energy levels are more severe than everyone's regular ups and downs (Rihmer & Kiss, 2002). Managing BD is complex; and social and occupational life disruptions are well-documented, including higher divorce rates, unemployment, and suicide (Marrag et al., 2015). Research has consistently shown individuals with BD have a higher mortality rate compared with the general population (Walker et al., …

Home Range Dynamics And Juvenile Dispersal Of Gray Hawks In The Lower Rio Grande Valley, Michael Stewart

Theses and Dissertations

Using GPS-GSM transmitters I determined when 14 juvenile Gray Hawks (Buteo plagiatus) in the Lower Rio Grande Valley of Texas fledged from their natal areas and how far they traveled once they dispersed. These transmitters also allowed me to calculate home range sizes for 22 adults. Additionally, with the GPS-GSM transmitters and 15 VHF transmitters, I discovered that adult Gray Hawks in the study area remained in their territories year-round. Home range sizes were calculated using the minimum convex polygon estimator, the estimation of kernel home-range, and the estimation of kernel Brownian bridge home-range. The same three methods allowed me …

Morphological Characterization And Functional Assessment Of Trichomes In Solanaceae, Sakshi Watts

Theses and Dissertations

Chapter 1: This chapter provides an overview of various trichome types in plants, and also empirically examines their variation on abaxial and adaxial leaf surface of 14 Solanum species. Detailed nomenclature, density, and dimension measurements of each trichome type has been provided using scanning electron-microscopy.

Chapter 2: Scanning electron microscopy was major component of methodology used in my thesis for scanning leaf samples to estimate trichome traits. In this chapter, a more efficient and cost-effective methodology for scanning electron microscopy has been explored.

Chapter 3: This chapter examines the relationship of trichome density and herbivore feeding behavior using abaxial and …

Two-Dimensional Black Phosphorus For Terahertz Emission And Near-Field Radiative Heat Transfer, Mahmudul Hasan Doha

Graduate Theses and Dissertations

The main focus of this work is to investigate two potential optical and optoelectronic applications of black phosphorus (BP): the near-field radiative heat transfer in plasmonic heterostructures with graphene and terahertz emission from multi-layer BP photoconductive antennas. When the separation distance between graphene-black phosphorene is much smaller than or comparable to the thermal wavelength at different temperatures, a near-field radiation heat transfer breaks the Planck blackbody limit. The magnitude of the near-field radiation enhancement acutely depends on the gate voltage, doping, and vacuum gap of the graphene and BP pair. The strong near-field radiation heat transfer enhancement of the specific …

Integrated Weed Management Strategies For Palmer Amaranth (Amaranthus Palmeri) In Cotton And Soybean Production Systems, Rodger Bruce Farr

Graduate Theses and Dissertations

Management of Palmer amaranth [Amaranthus palmeri (S.) Wats.] in the Midsouth in soybean [Glycine max (L.)] and cotton (Gossypium hirsutum L.) production systems has become increasingly troublesome due to resistance to many of the commonly utilized herbicides in these systems. Developments have been made to utilize new chemistries as well as incorporate integrated weed management strategies to control Palmer amaranth, but questions have risen given the economic feasibility or effectiveness of these new strategies. Additionally, regulation has limited producers’ abilities to utilize some herbicide chemistries. As a result, experiments were conducted to 1) understand the utility of isoxaflutole in isoxaflutole-tolerant …

Synthesis Of Polyethylene Glycol-Based Hydrogels And Silver/Gold Nanostructures For Biomedical Applications, Isabelle Ishimwe Niyonshuti

Graduate Theses and Dissertations

This work focuses on the synthesis of biocompatible polyethylene glycol (PEG)-based hydrogels, silver nanoparticles (AgNPs), and silver-gold nanocages (Ag-AuNCs) for biomedical applications. The dissertation includes two parts with Part I on the work of PEG-based hydrogel for wound healing applications and Part II on the work of Ag/Au nanostructures for antimicrobial applications. Part I studies PEG-based hydrogel for the delivery of fibroblast growth factors (FGFs) for wound healing applications, aiming to overcome the challenge of designing hydrogels capable of the sustained release of bioactive FGFs. This research develops new biocompatible anionic injectable hydrogel formulations based on Poly (Oligo Ethylene Glycol …

Invasive Carp Movement, Behavior, And Habitat Use: Evaluating Common Carp As A Surrogate For Bigheaded Carps, Alexander Catalano

Theses

Invasive species are a major concern for fish populations globally, and the ability to predict the susceptibility of ecosystems to additional invasions or range expansions is needed. Bigheaded carp [Silver Carp (Hypophthalmichthys moltrix) and Bighead Carp (H. nobilis)] pose a serious threat to the Great Lakes Basin and numerous other aquatic ecosystems, where suitable habitat for spawning could allow for the establishment of breeding populations. Evaluating a surrogate would be useful to predict how bigheaded carp behave beyond their current range. To determine whether Common Carp (Cyprinus carpio) is an appropriate surrogate for bigheaded carp, their potential overlap in diets, …

Reactivity Of O-Drug Bond In Some Suggested Voltarine Carriers: Semiempirical And Ab Initio Methods, Rehab M. Kubba, Mustafa M. Kadhim

Baghdad Science Journal

In this work, the possibility to use new suggested carriers (D= Aspirin, Ibuprofen, Paracetamol, Tramal) is discussed for diclofenac drug (voltarine) by using quantum mechanics calculations. The calculation methods (PM3) and (DFT) have been used for determination the reaction path of (O-D) bond rupture energies. Different groups of drugs as a carrier for diclofenac prodrugs (in a vacuum) have been used; at their optimized geometries. The calculations included the geometrical structure and some of the physical properties, in addition to the toxicity, biological activity, and NLO properties of the prodrugs, investigated using HF method. The calculations were done by Gaussian …

Study Of Certain Biomarkers In Iraqi Female Patients With Breast Cancer, Abeer M. Hussain, Ali Hussein Mohammed Al-Khafaji, Alia Hussain Ali, Haider Latif Mohammed

Baghdad Science Journal

The prospective study has been designed to determine some biomarkers in Iraqi female patients withbreast cancer. The current study contained 30 patients whose tissue samples have been collected fromhospitals in Medical City in Baghdad after consent patients themselves and used immunohistochemicaltechnique to determine these markers. The results showed a significant correlation between ER and PR tissuemarkers (Sig = 0.000) and a significant correlation between cyclin E phenotype and cyclin E intensity (Sig =0.001).

Educating Asian American College Students On The Importance Of Community And Mentorship, Jeah Limbag

Capstone Projects and Master's Theses

Many college students may find it challenging to discover and create a supportive and consistent community or establish meaningful relationships in school. Asian American college students, in particular, have cultural values, experiences, and ideologies that can limit seeking mentors and establishing a social support network. The consequences of this could be increased feelings of loneliness and isolation, worse mental health, lower academic performance, lower attendance, and an increased likelihood of dropping out of school. To address these challenges, I have created an interactive presentation bringing awareness of the importance of mentorship and community to students in the Asian and Pacific …

Assigning Assessment Accommodations To English Learners: A Phenomenological Study, Heather May Villalobos Pavia

Dissertations

The English learner (EL) student population has grown steadily for the past 20 years. During this time, the use of standardized assessments has increased as well. Teacher understanding of assessment accommodations that best support ELs is low, despite the research that shows the unreliability of standardized achievement tests that measure the academic achievement of ELs. The purpose of this qualitative, phenomenological study was to examine how 10 teachers engage in the assessment accommodation selection process. Teachers were intentionally selected from intermediate elementary grades where the most native (primary/home) language accommodations are available on state assessments. Data were collected through surveys, …

Prominent Women Wind Conductors In Higher Education: Trials, Triumphs, And Recommendations For Improving Gender Equity In The Field, Jennifer Lee Grice

Dissertations

This study investigated the past and present status of gender equity in the wind band conducting profession in higher education. Eight of the most prominent women in wind band conducting were interviewed on specific questions regarding their trials, triumphs, and recommendations for upcoming women conductors in the field. Interviewees included Andrea Brown, Paula Crider, Tonya Mitchell-Spradlin, Emily Moss, Catherine Rand, Courtney Snyder, Emily Threinen, and LaToya Webb. Discussion topics included personal musical journeys, role models/mentors, equity in the profession, challenges faced in their careers, personal score study/rehearsal techniques, how to help future women in the field, and other pertinent information. …

Identifying The Molecular Cause Of Extreme Endoplasmic Reticulum Dilation In Pediatric Osteosarcoma And Its Relationship To The Disease, Rachael Wood

Theses and Dissertations (ETD)

Pediatric osteosarcoma tumors are characterized by an unusual abundance of grossly dilated endoplasmic reticulum and an immense genomic instability that has complicated identifying new effective molecular therapeutic targets. Here we report a novel molecular signature that encompasses the majority of 108 patient tumor samples, PDXs and osteosarcoma cell lines. These tumors exhibit reduced expression of four critical COPII vesicle proteins that has resulted in the accumulation of procollagen-I protein within ‘hallmark’ dilated ER. Using CRISPR activation technology, increased expression of only SAR1A and SEC24D to physiologically normal levels was sufficient to restore both collagen-I secretion and resolve dilated ER morphology …

Characterizing And Overcoming Resistance To Aminomethylspectinomycins In Gram-Negative Bacteria, Nisha Das

Theses and Dissertations (ETD)

Spectinomycin (SPC) is a broad-spectrum aminocyclitol antibiotic. Its use in agriculture has led to widespread resistance in enteric bacteria, necessitating the development of more effective analogs. Aminomethyl spectinomycins (amSPC) are modified spectinomycins with increased potency against many bacterial species. These species include Legionella pneumophila, which harbors a chromosomally encoded aminoglycoside modifying enzyme (AME). In this study, we follow up on this observation and examine the extent to which the amSPCs are substrates for AMEs through adenylation (ANTs) and phosphorylation (APH). APH(9)-Ia and ANT(3")(9) were expressed in E. coli BL21(DE3) and purified using the Ni-affinity chromatography. The ability of AMEs to …

Examination Of Antiviral Resistance In Venezuelan Equine Encephalitis Virus, Jasper Lee

Theses and Dissertations (ETD)

Venezuelan equine encephalitis virus (VEEV) is a New World Alphavirus that causes Venezuelan equine encephalitis (VEE), which is characterized by a febrile illness that can progress to neurological disease and death. While no major outbreaks of VEE have occurred since 1995, VEEV is a virus of concern as, in addition to its spread through mosquitos, it can be aerosolized and used as a bioweapon. Unfortunately, there are currently no FDA-approved vaccines or antivirals against VEEV. Efforts have been made to discover small molecules with an inhibitory effect on VEEV, but the potential for emergence of antiviral resistance to these compounds …

The Effect Of Cancer Cachexia Progression On The Feeding Regulation Of Skeletal Muscle Protein Turnover, Brittany R. Franch

Theses and Dissertations (ETD)

Cancer cachexia is defined as the unintentional loss of skeletal muscle mass with or without fat loss that cannot be reversed by conventional nutritional support. Cachexia occurs in ~20% of cancer patients. More specifically, 50% of lung cancer patients, the most common cancer worldwide, develop cachexia. Cachexia occurs most often in lung and gastrointestinal cancers, whereas breast and prostate have the lowest rate of cachexia. Cancer-induced cachexia disrupts skeletal muscle protein turnover (decreasing protein synthesis and increasing protein degradation). Skeletal muscle’s capacity for protein synthesis is highly sensitive to local and systemic stimuli that are controlled by mTORC1 and AMPK …

Aryl Halides As Potential Components For O-Aryl-N-(9'-Acridinyl)-Hydroxylamines Antitumor Agents, Erin Munder

Master's Theses

Acridine derivatives such as m-amsacrine (m-AMSA) are known to intercalate deoxyribonucleic acid (DNA). Their action targets the growth, function, and replication of cancer cells. Because of this, they are primarily used as anticancer and antimalaria drugs. Unfortunately, due to the low half-life m-AMSA possesses because of the ease of hydrolysis of the carbon 9-nitrogen bond (C9-N bond), large concentrations of the drug are needed to be pharmaceutically effective. This results in a large concentration of toxic aniline byproducts. To reduce the rate of hydrolysis but still maintain the binding to DNA, a modification to the m-AMSA structure was made. A …

The Role Of The Erbb Signaling Pathway In Cardiovascular Progenitor Cell-Based Repair, Christopher Ramos

Electronic Theses, Projects, and Dissertations

Adult mammalian hearts lack self-renewal and proliferative capabilities necessary for cardiovascular regeneration. Current treatments using cardiac progenitor cells (CPCs) for cell-based repair do not restore cardiac function in patients who experience a myocardial infarction (MI). Our laboratory has been studying Islet-1+ neonatal CPCs as a promising candidate for cell-based repair due to their ability to significantly improve cardiac function after MI in sheep. The current study addresses the hypothesis that the ERBB pathway is linked to the Hippo-pathway to activate YAP1 by the involvement of an autocrine loop that upregulates neuregulin (NRG). In our sheep model of MI and cardiovascular …

A Small Molecule Produced By Lactobacillus Species Blocks Candida Albicans Filamentation By Inhibiting A Dyrk1-Family Kinase, Jessie Macalpine, Martin Daniel-Ivad, Zhongle Liu, Junko Yano, Nicole M. Revie, Robert T. Todd, Peter J. Stogios, Hiram Sanchez, Teresa R. O’Meara, Thomas A. Tompkins, Alexei Savchenko, Anna Selmecki, Amanda O. Veri, David R. Andes, Paul L. Fidel, Nicole Robbins, Justin Nodwell, Luke Whitesell, Leah E. Cowen

School of Dentistry Faculty Publications

The fungus Candida albicans is an opportunistic pathogen that can exploit imbalances in microbiome composition to invade its human host, causing pathologies ranging from vaginal candidiasis to fungal sepsis. Bacteria of the genus Lactobacillus are colonizers of human mucosa and can produce compounds with bioactivity against C. albicans. Here, we show that some Lactobacillus species produce a small molecule under laboratory conditions that blocks the C. albicans yeast-to-filament transition, an important virulence trait. It remains unexplored whether the compound is produced in the context of the human host. Bioassay-guided fractionation of Lactobacillus-conditioned medium linked this activity to 1-acetyl-β-carboline (1-ABC). We …

Efficacy Of Spirulina (Arthrospira Platensis) Utilization In Broiler Diets, Garrett James Mullenix

Graduate Theses and Dissertations

Spirulina (Arthrospira platensis) is a cyanobacteria microalgae that has potential as an animal feed ingredient. Five experiments were conducted to further assess its ability to serve as a protein source in broiler diets. Experiment 1 consisted of an amino acid digestibility and apparent metabolizable energy assay. The results indicated that the standardized ileal amino acid levels of spirulina are comparable with typical soybean meal. Experiment 2 assessed the performance and processing parameters of broilers fed 10% spirulina in low crude protein diets, using published digestibility coefficients. Spirulina inclusion improved footpad quality and increased redness and yellowness of the breast, skin …

Body Mass And Body Condition Variation Of Mallards (Anas Platyrhynchos) Within And Among Winters Within The Lower Mississippi Alluvial Valley, John Thompson Veon

Graduate Theses and Dissertations

Most North American waterfowl overwinter in southern North America before migrating back to breeding grounds in the northern US and Canada. These species face the challenge of needing to maintain or increase their body mass during an environmentally difficult winter period. Successful body mass maintenance during the winter period has major ramifications not only for their winter survival but for their fitness across the entire year. Recent research in Europe and the western United States suggests that the body mass of mallards (Anas platyrhynchos) has increased from the late 1960s to early 2000s. However, the factors responsible for increases in …

Trained Immunity Enhances The Immune Response And Maintains Microbiome Diversity In Aging And Sepsis, P. Spencer Gill

Electronic Theses and Dissertations

The global population is rapidly aging. It is estimated that over the next thirty years, the number of individuals >60 years of age will increase by over a billion, and the number of individuals over age 80 may increase by 300 million. As humans age, our immune system becomes progressively weaker through a process called immune senescence. This age-related decrease in immune function increases susceptibility to infection and chronic diseases. Sepsis is a leading cause of death worldwide. Over the past two decades, there has been an increased incidence of sepsis which is due, in part, to our aging population …

Correctional Career Pathways: A Jail Reentry Program Evaluation, Grace Gass

Electronic Theses and Dissertations

There are numerous types of reentry programs available to inmates to help avoid the cycle of recidivism. There is little research on the impacts of reentry programs in jail populations. This current study sought to provide more research in this area by evaluating a local jail reentry program’s effect on recidivism. A quasi-experimental design was used to estimate the program’s effectiveness by comparing the recidivism statistics of inmates that have participated in the reentry program to a control group of inmates that did not. Inmates in the control group were matched according to their gender, age, race, and current offense …

Lipidomic Analysis Of Various Developmental Stages Of Physcomitrium Patens, Deepshila Gautam

Electronic Theses and Dissertations

Lipids maintain fluidity of the cell membrane during the lifetime of all organisms. The moss Physcomitrium patens, an early land plant, enters reproductive phase under cold (15°C) conditions relative to its gametophytes (22°C). Thus, we hypothesized that their lipid content and composition would be distinct. Using ESI-MS/MS, we showed that the content and acyl composition of 11 lipid classes varied during development. Galactolipids were abundant in gametophytes but insignificant in sporophytes; among phospholipids, phosphatidylcholine was predominant in both phases. Although, sporophytes contained around five-fold less lipids than the gametophyte, their phosphatidic acid content, which accumulates during stress, was 18-fold …

Computational Analysis Of The Spin Trapping Properties Of Lipoic Acid And Dihydrolipoic Acid, Matthew Bonfield

Electronic Theses and Dissertations

While the spin trapping properties of thiols have been investigated through EPR analysis and kinetics studies, few groups have studied these properties using strictly computational methods. In particular, α-lipoic acid (ALA) and its reduced form, dihydrolipoic acid (DHLA), one of the strongest endogenously produced antioxidants, show potential for being effective, naturally occurring spin traps for the trapping of reactive oxygen species. This research covers electronic structure calculations of ALA, DHLA, and their corresponding hydroxyl radical spin adducts, performed at the cc-pVDZ/B3LYP/DFT level of theory. The effects on DHLA introduced by other radicals such as ·OOH, ·OCH₃, …

Genital Chlamydia Infection Is Influenced By The Female Sex Hormones Estrogen And Progesterone In Vivo, Amy Gail Gravitte

Electronic Theses and Dissertations

Chlamydia is the most common bacterial sexually transmitted infection in the United States and worldwide. It often goes unnoticed due to lack of symptoms and left untreated it can ascend the female genital tract to cause sequelae like pelvic inflammatory disease and irreversible tubal infertility. In reproductive-aged women, female sex hormones estrogen (E2) and progesterone (P4) concentrations fluctuate during the menstrual cycle and are influenced by hormonal contraceptives and hormone replacement therapy. E2 and P4 influence genital Chlamydia infection in women and mice, but these multifactorial interactions are not entirely mapped out. The complex interplay of E2 and P4 with …

Mesopredator Detection And Eastern Spotted Skunk Den Site Selection In North Carolina, Anna Siegfried

All Theses

Small carnivore assemblages have been a topic of interest for many years because of their potential top-down effect on communities. However, mesopredators are a challenge to investigate because of their small sizes and elusive behavior. Advances in technology, such as non-invasive trail cameras and smaller GPS tracking devices, have increased the success in monitoring these communities, and we are learning that some of these species’ populations have drastically declined, are currently declining, or the population status is unknown.

Adding an attractant to remote camera sites has become a popular method to increase detections of mesopredators. However, there is an ongoing …