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Effects Of Aging On Mouse Rotator Cuff Tendon Biomechanics, Chinmay Sagar Patwardhan

Bioengineering Theses - Archive

Rotator cuff tendon injuries and tear are caused by overuse, falling, or other accidents, and are often associated with old age. The severe injuries and tear can be debilitating and require nonsurgical treatment for partial tear and arthroscopic surgery for complete tear. The frequent location of injuries and tear are at the enthesis region, the interface where the tendon tissue gradually hardens and merges into the bone. Although aging has been identified as an important factor for rotator cuff tendon injuries and tear, how the mechanical properties of the bone-tendon complex evolve along with age is still a knowledge gap. …

Refocusing Agricultural Subsidy For Food Security In Nigeria, Sulaiman A. Yusuf

Economic and Financial Review

Food security has remained a key human right-related issue and ranks second only to poverty on the Sustainable Development Goals (SDGs). The objectives of this paper are to identify the gaps in agriculture subsidy regime; and to identify options for refocusing of the subsidy regime to improve food security.

Following the introduction, section 2 explores the nexus of agricultural subsidy and food security, while section 3 reviews the agricultural subsidy regime in Nigeria. Section 4 discusses the input-output dimensions of agricultural subsidy in Nigeria, and in section 5, the paper takes a dive into the agricultural subsidies from international perspective. …

Association Between Glycemic Control And Shift Working Among Healthcare Workers With Diabetes, Dammam, Saudi Arabia: Five Years’ Experience, Mona A. Albishri, Danah M. Alsubaie, Hassan A. Abugad

Saudi Medical Journal

Objectives: To delineate the relation between shift work and glycemic control among the healthcare workers (HCWs) with diabetes mellitus (DM) in the hospitals of Dammam, Saudi Arabia. Methods: A cross-sectional study was conducted among HCWs with DM working in 3 hospitals in Dammam, Saudi Arabia, from November 2018 to January 2019. The study participants answered a self-administered questionnaire related to sociodemographic data, work-related questions, diabetes-related questions, the latest hemoglobin A1C test outcome, and self-management activities. The Chi-square and t-test were used to determine the association between the risk factor of glycemic control and shift work. Results: The HCW’s ages ranged …

The Relationship Between Status Motives And Social Activism, Olajuwon Olagbegi

Honors Theses

Numerous social and cultural events have resulted in increased interest and participation in social activism in the United States, stemming from mounting dissatisfaction with social inequality. Though explanations have previously included increased issue exposure and awareness due to the proliferation of digital media and increases in progressive ideology amongst the nation’s younger generation, the current study tests the hypothesis that social activism may in part be motivated by interest in status acquisition, given the evolutionary value of status for securing access to resources and mates. To test this hypothesis, participants were randomly assigned to a status versus control priming condition …

Investigation Of N-Sulfonyliminium Ion Triggered Cyclizations For The Synthesis Of Piperidine Scaffolds, Kaitlyn Birkhoff

Honors Theses

In consideration of the on-going global pandemic, immediate access to Food and Drug Administration approved pharmaceutical medications and vaccines is a matter of utmost priority to our national healthcare system. One significant modality in managed care is the dispensation of prescription drugs for the prevention or treatment of illnesses and diseases. According to the Centers for Disease Control and Prevention, physicians order and provide over 2.9 billion prescriptions each year with analgesics, antihyperlipidemics, and dermatological agents being the most prescribed therapeutic classes. Within those classes exists a disparate variety of chemical structures that must be prepared on a metric ton …

Comparative Genome Analysis Of Fungal Antagonists Marinomonas Ostreistagni 398 And M. Spartinae 468., Jessie L. Fields

Honors Theses

Under certain conditions, the Spartina alterniflora and Juncus roemerianus grasses in marshes undergo progressive decline in an event known as Saltwater Marsh Dieback, which may be attributed to the presence of the plant pathogenic fungi Fusarium. The microbiomes of S. alterniflora and J. roemerianus from Deer Island, MS were characterized and Fusarium suppressing bacteria were identified. Among isolates capable of antagonizing Fusarium were Marinomonas ostreistagni 398 and M. spartinae 468. Despite the progress in understanding the diversity of Marinomonas, our ability to explain ecological, metabolic, and biochemical traits of marinomonads at the genomic sequence level remains limited. Analysis …

Gaze, Volume 8, Number 6

Gaze, 1979-1990

Co-Editors: Allen Cook, John Stilwell. Staff Writers: Carole Taylor, Bob Dumais. Typesetting and Layout: Allen Cook, Bob Dumais, Cecil McLeod, John Stilwell. Circulation: Cecil McLeod, John Stilwell, Bob Dumais. Advertising Manager: Bob Dumais.

Special thanks to Rhodes College and the Paul Barret Jr. Library for providing initial scanning of this collection.

Gaze, Volume 8, Number 4

Gaze, 1979-1990

Co-Editors: Allen Cook, John Stilwell. Staff Writers: Carole Taylor, Bob Dumais, Kellie China, Joyce Russell. Feature Writers: E.C., Bob Reynolds, Jr. Typesetting and Layout: Allen Cook, Bob Dumais, Cecil McLeod, John Stilwell. Circulation: Cecil McLeod, John Stilwell, Bob Dumais. Advertising Manager: Bob Dumais. Nashville Advertising: Kellie China, Joyce Russell.

Special thanks to Rhodes College and the Paul Barret Jr. Library for providing initial scanning of this collection.

Gaze, Volume 7, Number 6

Gaze, 1979-1990

Co-Editors: Allen Cook, John Stilwell. Staff Writers: Martin Palm-Leis, Carole Taylor, Bob Dumais, Charlie McMullen. Feature Writers: Dr. Harvey Thompson, Rev. Steven Quesnel, Nancy Roth. Typesetting and Layout: Allen Cook, Bob Dumais, Cecil McLeod, John Stilwell. Circulation: Cecil McLeod, John Stilwell, Bob Dumais. Advertising Manager: Bob Dumais. National Advertising: Rivendell Marketing.

Special thanks to Rhodes College and the Paul Barret Jr. Library for providing initial scanning of this collection.

Gaze, Volume 9, Number 1

Gaze, 1979-1990

Co-Editors: Allen Cook, John Stilwell. Staff Writers: Carole Taylor, Bob Dumais. Typesetting and Layout: Allen Cook, Bob Dumais, Cecil McLeod, John Stilwell. Circulation: Cecil McLeod, John Stilwell, Bob Dumais. Advertising Manager: Bob Dumais.

Special thanks to Rhodes College and the Paul Barret Jr. Library for providing initial scanning of this collection.

Gaze, Volume 7, Number 8

Gaze, 1979-1990

Co-Editors: Allen Cook, John Stilwell. Staff Writers: Carole Taylor, Bob Dumais, E.C., Kellie China, Joyce Russell, Landy, B.F.F. Feature Writers: Dr. Harvey Thompson, Rev. Steven Quesnel, Nancy Roth. Typesetting and Layout: Allen Cook, Bob Dumais, Cecil McLeod, John Stilwell. Advertising Manager: Bob Dumais. Nashville Advertising: Kellie China, Joyce Russell.

Special thanks to Rhodes College and the Paul Barret Jr. Library for providing initial scanning of this collection.

Gaze, Volume 9, Number 7

Gaze, 1979-1990

Co-Editors: Allen Cook, John Stilwell. Staff Writers: Carole Taylor, Bob Dumais, Vincent Astor, Becky Caperton, John House. Typesetting and Layout: Allen Cook, Bob Dumais, Cecil McLeod, John Stilwell. Circulation: Cecil McLeod, John Stilwell, Bob Dumais. Advertising Manager: Bob Dumais.

Special thanks to Rhodes College and the Paul Barret Jr. Library for providing initial scanning of this collection.

This issue is the first of two issues printed as volume 9, number 7.

Gaze, January 2008

Gaze, 1979-1990

"An independent newspaper for the Memphis GLBT Community." This issue is dated Mid-January 2008.

Special thanks to Rhodes College and the Paul Barret Jr. Library for providing initial scanning of this collection.

Gaze, Volume 11, Number 8

Gaze, 1979-1990

Co-Editors: Allen Cook, John Stilwell. Staff Writers: Vincent Astor, Becky Caperton. Typesetting and Layout: Allen Cook, John Stilwell, Vincent Astor. Circulation: Cecil McLeod, John Stilwell. Advertising: Vincent Astor.

This issue is noted as the July and August edition.

Special thanks to Rhodes College and the Paul Barret Jr. Library for providing initial scanning of this collection.

Gaze, Volume 11, Number 6

Gaze, 1979-1990

Co-Editors: Allen Cook, John Stilwell. Staff Writers: Vincent Astor, Ken Horton, Becky Caperton. Typesetting and Layout: Allen Cook, John Stilwell, Vincent Astor. Circulation: Cecil McLeod, John Stilwell. Advertising: Vincent Astor.

Special thanks to Rhodes College and the Paul Barret Jr. Library for providing initial scanning of this collection.

Writing Skills Development For Graduate Studies And Career Readiness In Science And Aging Fields: A Case Study Approach, Amanda Stafford Mcrell, Betty L. White, Sue E. Levkoff

Faculty and Staff Publications

Increasing the number of racially and ethnically underrepresented students who pursue scientific graduate studies in programs focusing on science and aging offers an opportunity to increase the number of aging specialists while simultaneously promoting diversity in the research labor market and supporting new ideas. This case study aims to better understand how students participating in an academic preparatory program experience a writing class contextualized within (1) students' writing background and (2) students' future ambitions related to science and aging. The individually-tailored writing class was taught as a critical component of a comprehensive educational program that targets underrepresented racial and ethnic …

Whole-Genome Association Analyses Of Sleep-Disordered Breathing Phenotypes In The Nhlbi Topmed Program, Brian E. Cade, Brian E. Cade, Jiwon Lee, Tamar Sofer, Heming Wang, Man Zhang, Han Chen, John Blangero, Joanne E. Curran, Juan M. Peralta

School of Medicine Publications

Background: Sleep-disordered breathing is a common disorder associated with significant morbidity. The genetic architecture of sleep-disordered breathing remains poorly understood. Through the NHLBI Trans-Omics for Precision Medicine (TOPMed) program, we performed the first whole-genome sequence analysis of sleep-disordered breathing. Methods: The study sample was comprised of 7988 individuals of diverse ancestry. Common-variant and pathway analyses included an additional 13,257 individuals. We examined five complementary traits describing different aspects of sleep-disordered breathing: the apnea-hypopnea index, average oxyhemoglobin desaturation per event, average and minimum oxyhemoglobin saturation across the sleep episode, and the percentage of sleep with oxyhemoglobin saturation < 90%. We adjusted for age, sex, BMI, study, and family structure using MMSKAT and EMMAX mixed linear model approaches. Additional bioinformatics analyses were performed with MetaXcan, GIGSEA, and ReMap. Results: We identified a multi-ethnic set-based rare-variant association (p = 3.48 × 10−8) on chromosome X with ARMCX3. Additional rare-variant associations include ARMCX3-AS1, MRPS33, and C16orf90. Novel common-variant loci were identified in the NRG1 and SLC45A2 regions, and previously associated loci in the IL18RAP and ATP2B4 regions were associated with novel phenotypes. Transcription factor binding site enrichment identified associations with genes implicated with respiratory and craniofacial traits. Additional analyses identified significantly associated pathways. Conclusions: We have identified the first gene-based rare-variant associations with objectively measured sleep-disordered breathing traits. Our results increase the understanding of the genetic architecture of sleep-disordered breathing and highlight associations in genes that modulate lung development, inflammation, respiratory rhythmogenesis, and HIF1A-mediated hypoxic response.

Maternal Investment, Life-History Trajectory Of The Off-Spring And Cardiovascular Disease Risk In Emirati Females In The United Arab Emirates, Rola Al Ghali, Linda Smail, Maryam Muqbel, Dalia Haroun

All Works

Background: Variations in cardiovascular disease risk (CVD) are suggested to be partly influenced by factors that affect prenatal growth patterns and outcomes, namely degree of maternal investment (proxied by birth weight and gestational age). Using the life history trajectory model, this study investigates whether maternal investment in early prenatal life associates with menarcheal age and whether maternal investment affects CVD risk in adulthood and predicts adult size and adiposity levels. Methods: A cross-sectional study was conducted among 94 healthy Emirati females. Birth weight, gestational age and menarcheal age were obtained. Anthropometrical measurements, body composition analysis, and blood pressure values were …

Multiomic Analysis Of The Arabian Camel (Camelus Dromedarius) Kidney Reveals A Role For Cholesterol In Water Conservation, Fernando Alvira-Iraizoz, Benjamin T. Gillard, Panjiao Lin, Alex Paterson, Audrys G. Pauža, Mahmoud A. Ali, Ammar H. Alabsi, Pamela A. Burger, Naserddine Hamadi, Abdu Adem, David Murphy, Michael P. Greenwood

All Works

The Arabian camel (Camelus dromedarius) is the most important livestock animal in arid and semi-arid regions and provides basic necessities to millions of people. In the current context of climate change, there is renewed interest in the mechanisms that enable camelids to survive in arid conditions. Recent investigations described genomic signatures revealing evolutionary adaptations to desert environments. We now present a comprehensive catalogue of the transcriptomes and proteomes of the dromedary kidney and describe how gene expression is modulated as a consequence of chronic dehydration and acute rehydration. Our analyses suggested an enrichment of the cholesterol biosynthetic process and an …

The Role Of The Next Generation Science Standards In Teachers' Curricular Choices In The Life Science Classroom, Amy Tankersley

Department of Teaching, Learning, and Teacher Education: Theses and Other Student Research

In 2013 a group of experts used A Framework for K-12 Science Education (NRC, 2012) to draft the Next Generation Science Standards (NGSS), which aims to increase science literacy through integrating the concepts and practices of science into comprehensive standards for science (NGSS Lead States, 2013). As students learn to explore the content and practices of scientists, ideally, they should increase their ability to think and reason in ways that will benefit their ability to participate in society. Because of the complex nature of systematic education reform, teachers need to put significant time into implementing NGSS to fulfill the goals …

Socio-Economic And Environmental Issues: Implications For Food Security In Nigeria, Isaiah O. Olurinola, Evans Osabuohien

Economic and Financial Review

Socio-economic activities within the agricultural sector have witnessed significant changes in recent times. Two major factors account for this recent development. Available evidence shows that over the last four decades, environmental challenges (such as pollution, extreme weather, fire disaster and deforestation, among others) have been on the increase in Nigeria. This is complicated by a weak institutional framework to stem the tide (Egbetokun et al., 2018; 2020). Also, the information from Nigeria Meteorological Agency (NIMET) shows that the annual mean climatic conditions (that is rainfall and temperature) in Nigeria have witnessed huge variation (NIMET, 2020; Egbetokun et al., 2020), which …

Socio-Economic And Environmental Issues: Implications For Food Security In Nigeria, Isaiah O. Olurinola, Evans Osabuohien

Economic and Financial Review

Nigeria has made many policies toward improving the contribution of the agricultural sector in the economy; however, there is a need to fine-tune some of the policies, particularly regarding food security.

There is a need for systemic intervention in the transformation of the agricultural sector including the modernisation/formalisation of the informal sector. T

Therefore, this paper sets out to, among others, investigate the state of food security in Nigeria, especially in relation to the current socio-economic and environmental issues affecting agricultural productivity, and then proffers some policy analytical models and recommendations for ensuring food security in the country.

(R1412) Stability And Bifurcation Of A Cholera Epidemic Model With Saturated Recovery Rate, Huda Abdul-Satar, Raid K. Naji

Applications and Applied Mathematics: An International Journal (AAM)

In this paper, a Cholera epidemic model is proposed and studied analytically as well as numerically. It is assumed that the disease is transmitted by contact with Vibrio cholerae and infected person according to dose-response function. However, the saturated treatment function is used to describe the recovery process. Moreover, the vaccine against the disease is assumed to be utterly ineffective. The existence, uniqueness and boundedness of the solution of the proposed model are discussed. All possible equilibrium points and the basic reproduction number are determined. The local stability and persistence conditions are established. Lyapunov method and the second additive compound …

A Linear Dynamical Perspective On Epidemiology: Interplay Between Early Covid-19 Outbreak And Human Mobility, Shakib Mustavee

Electronic Theses and Dissertations, 2020-2023

This research investigates the impact of human activity and mobility (HAM) in the spreading dynamics of an epidemic. Specifically, it explores the interconnections between HAM and its effect on the early spread of the COVID-19 virus. During the early stages of the pandemic, effective reproduction numbers exhibited a high correlation with human mobility patterns, leading to a hypothesis that the HAM system can be studied as a coupled system with disease spread dynamics. This study applies the generalized Koopman framework with control inputs to determine the nonlinear disease spread dynamics and the input-output characteristics as a locally linear controlled dynamical …

Development Of Comprehensive Theoretical Morphospaces For Canine Cranial Morphology, Alexa Ortega, Nicholas Hebdon, Lindsay Waldrop

Student Scholar Symposium Abstracts and Posters

Throughout the evolution of the family Canidae, there is a continuous belief that canines have an exceptional olfactory system which allows them to have a heightened sense of smell. Because of this olfactory sophistication, canines have become prevalent as detection animals in the military, homeland security, law enforcement, forensics, and civilian applications. However, while the trait is highly regarded, the exact role of nasal morphology is understudied. We aim to investigate the influences of nasal cavity and internal structure morphology in odor detection. However, nasal structure is a sophisticated morphological target and requires innovative solutions to capture the key variables …

Serine/Threonine Protein Phosphatase 1-Α (Stpp1-Α) From Black Tiger Shrimp, Penaeus Monodon, An Immune-Related Gene, Jacqueline Marjorie Pereda, Neil Andrew Bascos, Mudjekeewis Santos

The Philippine Agricultural Scientist

Reversible protein phosphorylation is a significant regulatory mechanism in many cellular functions, such as the dephosphorylation of Serine/Threonine protein residues catalyzed by protein phosphatase. In this study, the full-length STPP1-α gene from Penaeus monodon was cloned, characterized, and analyzed for its constitutive expression in WSSV-negative P. monodon organs. The gene was originally an isotig isolated from the gills of P. monodon that survived WSSV infection. PmSTPP1-α gene (GenBank: KX385833) has a total of 2 171 bp, with a 990 open reading frame (ORF) that encodes 329 amino acids (aa), sharing a 93% sequence identity with human Serine/Threonine PP1-α …

Rearing Silver Therapon Leiopotherapon Plumbeus (Teleostei: Terapontidae) Larvae Using Euryhaline Rotifers As Starter Food, Frolan A. Aya, Vicar Stella Nillasca, Luis Maria B. Garcia

The Philippine Agricultural Scientist

The silver therapon Leiopotherapon plumbeus is an important but dwindling freshwater food commodity in the Philippine freshwater habitats. The influence of feeding regimes on growth performance and survival of first-feeding silver therapon larvae fed euryhaline rotifers (Brachionus rotundiformis and B. plicatilis) as starter food was examined. Larvae at two days post-hatch (DPH) (1.93 ± 0.07 mm; 200 larvae/basin) were initially reared on rotifers for 12 days followed by Artemia nauplii from 14 to 35 DPH as follows: (A) B. rotundiformis from 2-13 DPH; (B) B. rotundiformis from 2-7 DPH and Moina micrura from 8-13 DPH; and (C) B. …

Investigating The Relations Between Caffeine-Derived Metabolites And Plasma Lipids In 2 Population-Based Studies, Dusan Petrovic, Menno Pruijm, Belén Ponte, Nasser A. Dhayat, Daniel Ackermann, Georg Ehret, Nicolas Ansermot, Bruno Vogt, Pierre-Yves Martin, Jesus D. Melgarejo

School of Medicine Publications

Objective: To investigate the relations between caffeine-derived metabolites (methylxanthines) and plasma lipids by use of population-based data from 2 European countries.

Methods: Families were randomly selected from the general population of northern Belgium (FLEMENGHO), from August 12, 1985, until November 22, 1990, and 3 Swiss cities (SKIPOGH), from November 25, 2009, through April 4, 2013. We measured plasma concentrations (FLEMENGHO, SKIPOGH) and 24-hour urinary excretions (SKIPOGH) of 4 methylxanthines-caffeine, paraxanthine, theobromine, and theophylline-using ultra-high-performance liquid chromatography-tandem mass spectrometry. We used enzymatic methods to estimate total cholesterol, high-density lipoprotein cholesterol, and triglyceride levels and the Friedewald equation for low-density lipoprotein cholesterol …

Habitat And Environmental Risks Of Chagas Disease In Low-Income Colonias And Peri-Urban Subdivisions In South Texas, Bára Šafářová, Cecilia H. Giusti, Maria P. Perez, Italo B. Zecca, Ester S. Carbajal, Gabriel L. Hamer, Sarah A. Hamer

School of Medicine Publications

Both the planning and public health literature have discussed proximity to greenspaces as predominantly beneficial to health, based on studies mostly conducted in high-income regions. Understanding the health risks of proximity to greenspace and nature—where pathogens and wildlife coexist—is important, as nature-based solutions are increasingly called for to address complex urban challenges. This exploratory pilot study bridges planning and epidemiology approaches to develop a new method to analyze habitat and environmental factors associated with the risk of vector-borne Chagas disease in a low-income region, South Texas. Chagas disease is endemic in Latin America, where it affects between seven to eight …

Recapture And Reuse Of Nitrogen And Phosphorus From Rendered Animal Materials To Enhance Nutrient Use Efficiency And Produce Quality In Agricultural Crop, Bhupinder Jatana

All Dissertations

The current fertilizer regime heavily relies on inorganic fertilizers to meet the crop nitrogen (N) and phosphorus (P) demand. However, the United States has a limited N production capacity, with 50% N demand met through imports. On the other hand, the nonrenewable natural reserves of P are being depleted at an unprecedented rate and are expected to be exhausted with in next 100 years. Additionally, high solubility/liability of the field applied inorganic fertilizers often results in lower nutrient use efficiency (NUE;

The MBM led to rapid N mineralization, with 35% of the applied N mineralized within the first five days …