Digital Commons Network^™

Abdominal Computed Tomography Imaging Findings In Hospitalized Covid-19 Patients: A Year-Long Experience And Associations Revealed By Explainable Artificial Intelligence., Alice Scarabelli, Massimo Zilocchi, Elena Casiraghi, Pierangelo Fasani, Guido Giovanni Plensich, Andrea Alessandro Esposito, Elvira Stellato, Alessandro Petrini, Justin Reese, Peter N Robinson, Giorgio Valentini, Gianpaolo Carrafiello

Faculty Research 2021

The aim of this retrospective study is to assess any association between abdominal CT findings and the radiological stage of COVID-19 pneumonia, pulmonary embolism and patient outcomes. We included 158 adult hospitalized COVID-19 patients between 1 March 2020 and 1 March 2021 who underwent 206 abdominal CTs. Two radiologists reviewed all CT images. Pathological findings were classified as acute or not. A subset of patients with inflammatory pathology in ACE2 organs (bowel, biliary tract, pancreas, urinary system) was identified. The radiological stage of COVID pneumonia, pulmonary embolism, overall days of hospitalization, ICU admission and outcome were registered. Univariate statistical analysis …

Intelligent Resource Prediction For Hpc And Scientific Workflows, Benjamin Shealy

All Dissertations

Scientific workflows and high-performance computing (HPC) platforms are critically important to modern scientific research. In order to perform scientific experiments at scale, domain scientists must have knowledge and expertise in software and hardware systems that are highly complex and rapidly evolving. While computational expertise will be essential for domain scientists going forward, any tools or practices that reduce this burden for domain scientists will greatly increase the rate of scientific discoveries. One challenge that exists for domain scientists today is knowing the resource usage patterns of an application for the purpose of resource provisioning. A tool that accurately estimates these …

Building A Repertoire Of Joint Attention Bids In Children With Autism, Erica Jordan Rackers

Graduate Theses/Dissertations

The current study extended previous research through evaluating if a multiple-probe procedure including auditory scripts and script-fading procedures could build a generalized repertoire of initiating bids for joint attention in three young children with autism. Stimuli were selected from four categories. Three categories were associated with teaching procedures and within-category generalization. The fourth category was associated with across-category generalization. The four categories were (a) visually alluring toys, (b) strangely placed objects, (c) large pictures, and (d) sounds. Category assignments in which teaching procedures or generalization were assessed were counterbalanced across the participants. Three different auditory scripts were selected and used …

Nicu Experiences Of Adoptive Parents & Desired Preparation, Catherine J. Howe

Graduate Theses/Dissertations

Parents who have newborns admitted into the Neonatal Intensive Care Unit (NICU) have multiple experiences and emotions. Additional social and emotional layers are experienced by adoptive couples when the infant they wish to adopt needs specialized care. This research study was completed to find out what adoptive parents experience in the NICU and what preparation would have been helpful. The method included semi-structured, open-ended interviews with seven couples who adopted a newborn at a Midwestern adoption agency within the past three years and had a NICU experience. The results described adoptive couples’ experiences on the unit, bonding and attachment, fears …

Expression And Purification Of Cytochrome 2u1 And Canine 1a2 And Metabolism Of Caffeine By Cytochrome 1a2, Brenda M. Wekesa

Graduate Theses/Dissertations

Cytochrome P450 enzymes are a large family of membrane heme proteins involved in eliminating drugs and the synthesis or elimination of steroids, eicosanoids, and vitamins. CYP2U1 is one of the poorly characterized P450 enzymes classified as orphan cytochrome P450 with unknown exact biological function. It is expressed in the brain and thymus as a catalyst in the hydroxylation of arachidonic acid. Unlike other cytochrome P450s, CYP2U1 is a bit unusual with forty extra amino acids. If a mutation occurs, it can lead to an early onset inherited disorder of the central nervous system called Hereditary Spastic Paraplegias (HSP). Most of …

Why An Improper Venue Can Have Lasting Effects On The Intersection Of Sport And Human Rights, Jenna Ebersbacher

Arbitration Law Review (2009 - Present)

No abstract provided.

Hypothetical Ai Arbitrators: A Deficiency In Empathy And Intuitive Decision-Making, Cole Dorsey

Arbitration Law Review (2009 - Present)

No abstract provided.

Effects Of Abstinence-Based Sexual Education Compared To Evidence-Based Sexual Education In K-12 Schools, Lily Probst

The Eleanor Mann School of Nursing Undergraduate Honors Theses

Background: Historically, sexual education in the United States has been abstinence-based (ABSE), meaning that sexual education is centered around encouraging adolescents to abstain from sexual activity outside of wedlock. On the other hand, evidence-based sexual education (EBSE) includes abstinence in its curriculum but does not emphasize it, instead highlighting contraception and prevention strategies. Additionally, EBSE teaches adolescents about healthy relationships, attitudes towards sexuality, gender roles, and provides resources for sexual and reproductive health services. Supplying adolescents in K-12 schools with access to evidence-based sexual education may not only decrease teen pregnancy rates and incidence of sexually transmitted infections (STIs) but …

Bullying Experiences Among Families And Children With Autism Spectrum Disorder, Developmental Delay, Or Varying Ethnicities, Emma Humphrey

The Eleanor Mann School of Nursing Undergraduate Honors Theses

Bullying perpetration in schools is a significant problem within the United States that has shown to increase mental health issues and adverse outcomes in children. The purpose of this extended literature review is to evaluate the significance of bullying in children with developmental delay (autism spectrum disorder) and majority and minority ethnic groups. The review of literature analyzes implications of bullying within these vulnerable populations and the family factors associated with peer victimization. An analysis from twenty peer-reviewed chosen articles reflects heightened levels of bullying, mental health problems, and negative experiences of all researched populations. The increased amount of victimization …

King Mackerel (Scomberomorus Cavalla), Aubrey L. Anthony, Erin Keeley, David Kerstetter

All Scans: Kerstetter Fisheries and Avian Ecology 3D Scan Series

Neurocranium from [length] cm total length (TL) King Mackerel (Scomberomorus Cavalla), collected from Bravo Market on 11/16/2021 by Aubrey Anthony

An Exploration Of Effective Patient Education With An Emphasis On Concussion, Kayla M. Ruopp

Health, Human Performance and Recreation Undergraduate Honors Theses

Concussion is a prevalent healthcare issue in the US, with approximately 1.6-3.8 million sports and recreation-related concussions each year in all ages. A concussion can be defined as a traumatic brain injury caused by biomechanical forces. When an athlete sustains a concussion, a physiologic cascade of events occurs. The most common signs and symptoms of a concussion include: loss of balance, disorientation, headache and confusion. Concussion assessments are important in order to determine the presence of an impairment and there are a multitude of tests that clinicians can use in order to isolate each type of damage. Studies have shown …

The Relationship Between Gestational Diabetes And Stress: A Literature Review, Morgan Mcgrath

The Eleanor Mann School of Nursing Undergraduate Honors Theses

The incidence of gestational diabetes has been increasing over the past ten to twenty years. The purpose of this literature review is to gather existing literature to examine the relationship between gestational diabetes and oxidative stress. Twenty peer-reviewed articles from two databases were selected to be examined in this review. From these studies, it was found that oxidative stress was higher in women who were diagnosed with gestational diabetes, and supplementation with vitamins and minerals was beneficial in decreasing stress in these women. While these studies can help healthcare providers in educating women who have been diagnosed, more research should …

A Black-Footed Ferret And U.S. Law: Lessons Learned From The First Successful Clone Of A Native U.S. Endangered Species, Lauren Corey

North Carolina Journal of Law & Technology

No abstract provided.

Exploring Hydrologic Responses To Different Wildfire Spatial Patterns Through The Lens Of Computational Modeling, Luke M. Telfer

Boise State University Theses and Dissertations

Severe wildfire disturbances are becoming increasingly common in high-elevation forests of the western United States. These fires alter watershed hydrologic processes, threatening critical downstream water resources and aquatic ecosystems. However, watershed-scale postfire hydrologic responses and water balance changes are highly uncertain. While postfire effects on individual processes such as runoff, infiltration, evapotranspiration, and snow dynamics are relatively well known, the role of wildfire spatial patterns in governing hydrologic connectivity and interactions between water balance components is poorly understood due to challenges associated with measuring and comparing fires at large scales. This thesis aims to examine pattern-related postfire interactions between various …

Bioactivity Assessment Of Veratrum Californicum Alkaloids, Madison Dirks

Boise State University Theses and Dissertations

The native Idaho plant Veratrum californicum is known to contain steroidal alkaloids that function as inhibitors of hedgehog signaling, a pathway utilized for the growth and differentiation of cells as well as proper tissue development. Veratrum californicum was originally noticed when pregnant ewes consumed the plant and later gave birth to lambs with craniofacial mutations such as a cyclopean eyes. These malformations were caused by the plant’s steroidal alkaloid cyclopamine blocking the hedgehog signaling pathway. This same pathway is used by more than 20 types of cancer for multiplication of cells. Additional alkaloids have been found in Veratrum californicum, …

The Influence Of Positive School Orientation And Teacher Attachment On Adolescent Mental Health Outcomes: Investigating Possible Group Differences, Within A Social And Emotional Learning Curriculum, Stefanie Diann Holloway

Boise State University Theses and Dissertations

Social and emotional learning (SEL) interventions can be delivered universally in schools to help equalize opportunities for diverse students and improve their mental health, as well as other outcomes. However, it is not always known or fully understood which underlying mechanisms may be at play that enable these interventions to achieve their effects –or how such mechanisms may develop over time, within an SEL intervention. The primary purpose of this study was to determine how one such intervention, Positive Action, was able to improve adolescent students’ mental health outcomes, by testing the potential mediational influences of students’ levels of …

Mechanisms For Extracellular Matrix-Dependent Blood-Brain Barrier Dysfunction, Brian Adam Hoettels

Boise State University Theses and Dissertations

Dysfunction of the blood vessels that form the blood-brain barrier (BBB) is observed across various neurological disorders, including multiple sclerosis (MS). As barrier loss culminates in neuronal dysfunction and degeneration, a better understanding of the mechanisms underlying BBB dysfunction is needed.

Tight junctions are multiprotein complexes maintained by the endothelial cells lining the inner blood vessel wall to seal the intercellular space, and their disruption impairs BBB function. In my first chapter, I focus on how tight junctions are altered in CNS inflammatory demyelinating diseases (CNS-IDDs) like MS as BBB dysfunction is one of the earliest known stages in …

The Role Of Berberine, A Clinically Relevant Plant Derived Alkaloid, In T Cell-Mediated Immunosuppression, Alexandra Adorno Vita

Dissertations

The primary focus of this research was to determine the effect of berberine (BBR), a clinically relevant plant-derived alkaloid, on follicular T helper (Tfh) cell activation and differentiation, with implications for the generation of T cell-dependent humoral responses. This research revealed a novel function of BBR as a suppressor of Tfh cell proliferation in secondary lymphoid organs of BBR-treated mice that underwent immunization for arthritis induction in a collagen-induced arthritis (CIA) mouse model. Tfh cells provide signaling to B cells that is crucial for the generation of T cell-dependent humoral responses, such as affinity maturation, isotype class switching, and the …

Biochemical Ecology Of The Western Rattlesnakes: Venom Variation And Toxin Profiling Of The Crotalus Viridis/Oreganus/Scutulatus Complex, Cara Smith

Dissertations

Biochemical ecology examines the complex and dynamic relationships between organisms and their environment from a molecular perspective. This requires a holistic integration of ecology, evolution, and natural history with the fine-scale resolution of molecular biology and functional biochemistry. Venomous snakes have evolved a wide variety of extreme behavioral, physiological, and biochemical adaptations for prey capture, making them an ideal model for the study of predator trait evolution and protein adaptation. However, venoms must be understood from an ecological perspective in order to comprehend the evolutionary forces that shape the diversity of toxin families present in venoms. This holistic picture has …

Relationships Between Working Class, First Generation College Students And Their Parent(S)/Guardian(S): A Phenomenological Study On The Impacts Of Middle Class Socialization, Lindsay Ellen Mason

Dissertations

This constructionist phenomenological dissertation study explored stories from nine working class, first generation college students, specifically how middle class socialization on a four year university campus located in the Mountain West region of the United States impacts the relationships with their parent(s)/guardian(s). My primary research question was: How does attending college at a 4 year public university influence first generation, working class students’ relationships with the ir parent(s)/guardian(s)? My sub research questions were: What role does middle class socialization that occurs on a 4 year public university campus play in impacting this relationship? And what role does online learning/remote learning …

Biofortification As A Sustainable Solution For 'Hidden Hunger': Evaluating Its Impact On The Environment, Nutrition, Culture, And Ethics, Elysia Lewis

Honors Theses

Micronutrient malnutrition, also referred to as ‘hidden hunger’, negatively impacts the health of millions of people around the world. Because of this, several strategies to reduce malnutrition have been proposed, one of which is biofortification. The process of biofortification increases the nutrient content of plants during their vegetative life cycle. Research has been conducted that shows the ability of biofortification to increase micronutrient content in crops, so the next step is successful implementation and adoption by consumers. This paper reviews several publications that look at biofortification with respect to the environment, sustainability, human nutrition, culture, and ethics from a variety …

The Complexities Of Conscience: Reconciling Death Penalty L Aw With Capital Jurors’ Concerns, Meredith Martin Rountree, Mary R. Rose

Buffalo Law Review

Jurors exercise unique legal power when they are asked to decide whether to sentence someone to death. The Supreme Court emphasizes the central role of the jury’s moral judgment in making this sentencing decision, noting that it is the jurors who are best able to “express the conscience of the community on the ultimate question of life or death.” Manylower courts nevertheless narrow the range of admissible evidence at the mitigation phase of a capital trial, insisting on a standard of legal relevance that interferes with the jury’s ability to exercise the very moral judgment the Supreme Court has deemed …

Site-Specific Effects Of Lysine Acetylation On Aminoacyl-Trna Synthetase, Hao Chen

Graduate Theses and Dissertations

Aminoacyl-tRNA synthetases (AARSs) are an ancient and highly conserved family of enzymes which can catalyze a two-steps aminoacylation reaction to charge tRNAs with their cognate amino acids, thus playing crucial roles in ribosomal protein synthesis. Naturally, the accurate amino acids and tRNA recognition of these synthetases are essential to the fidelity of translation process. To assure the correct recognition, some of these synthetases have evolved with an editing function to help remove the mischarged tRNAs. In addition to these functions, AARSs are also involved in various biological processes ranging from transcription to translation. Currently, a series of proteomic studies have …

Canine Microwear In Relation To Diet In Sumatran Primates And African Great Apes, Putu Pujiantari

Graduate Theses and Dissertations

This thesis considers canine microwear in relation to diet in five Sumatran primates (Pongo abelii, Hylobates lar, Hylobates agilis, Presbytis thomasi, and Macaca fascicularis) and two African great apes (Pan paniscus and Pan troglodytes schweinfurthii) using both microwear texture analysis and microwear feature analysis techniques. Statistical results for texture analysis show that there are significant differences in scale of maximum and heterogeneity. This indicates that some species have large pits on their canine surfaces, having these dominated by deep features at coarse scale yet have a slight microwear heterogeneity. For feature analysis, all variables show statistically significant variation. Variance in …

Memetic Rhetorical Theory: An Analytic Model For The Spread Of Information Online, Carleigh J. Davis

English and Technical Communication Faculty Research & Creative Works

Modern discourse is often characterized by such extreme polarization that participants operate from entirely different sets of facts. These alternative facts represent a new line of inquiry for rhetoricians, who must determine how false facts gain credibility. This article outlines Memetic Rhetorical Theory (MRT), a model for understanding how information evolves to become credible in a given environment.

Resource Gaps For Minority Entrepreneurs: A Study Of 3 Cities, Merissa Piazza, Iryna Lendel, Shneur Kushner, Jack Yochum

All Maxine Goodman Levin School of Urban Affairs Publications

This study aims to assess minority resource gaps in entrepreneurial ecosystems (EEs) in three cities across Ohio: Cleveland, Toledo, and Dayton. This report seeks to answer two main research questions: 1) What are the local factors of EEs that drive growth for minority entrepreneurs? And 2) Across three sites in Ohio, what are the gaps in access to different resources for minority entrepreneurs in the ecosystem? This report covers the first year of this project’s findings as the project team engaged with all three region’s ecosystems in 2021.

A Preliminary Investigation Into The Effects Of Lucilia Sericata (Meigen) Blow Fly Larval Feeding On Sharp Force Trauma (Sft) Wound Patterns In Decomposing Bones Of Sus Scrofa Domesticus, Erica L. Klafehn

Student Theses

An important aspect of forensic investigations involves the characterization and analysis of bone related trauma as this can provide valuable information regarding the manner and circumstances of death. Bone trauma can be classified into three main categories, which include Sharp Force Trauma (SFT), Blunt Force Trauma (BFT), and Gunshot Trauma. Previous experiments have explored SFT on flesh and bones, specifically made with knives or saws, coupled with various microscopic analytical methods. Minimal research has been done integrating both a forensic entomology and forensic anthropology approach, so it is imperative to understand previous literature detailing the behaviors of insects (blow flies), …

Tavr In Older Adults: Moving Toward A Comprehensive Geriatric Assessment And Away From Chronological Age: Jacc Family Series, Joy M Schmitz, Scott D Lane, Michael F Weaver, Ponnada A Narayana, Khader M Hasan, Delisa D Russell, Robert Suchting, Charles E Green

Faculty, Staff and Student Publications

Cocaine use continues to be a significant public health problem with limited treatment options and no approved pharmacotherapies. Cognitive-behavioral therapy (CBT) remains the mainstay treatment for preventing relapse, however, people with chronic cocaine use display cognitive impairments that are associated with poor response to CBT. Emerging evidence in animal and human studies suggests that the peroxisome proliferator-activated receptor-gamma (PPAR- γ) agonist, pioglitazone, improves white matter integrity that is essential for cognitive function. This project will determine whether adjunctive use of pioglitazone enhances the effect of CBT in preventing relapse during the early phase of recovery from cocaine use disorder. This …

The Relationship Between The Practice Of Martial Arts, Anxiety, Wellness, And Self-Efficacy, William K. Knight Jr

LSU New Orleans Theses and Dissertations

Although anxiety is a frequently researched topic, the growing numbers of diagnosed cases and the state of the present outcomes warrant the study of alternative approaches to address the causes and conditions of its prevalence, as well as possible adaptive strategies and tactics to improve outcomes for clients with anxiety. Counseling distinguishes itself in part due to its focus on well-being rather than mere alleviation of diagnosed symptoms. As such, it may be useful to measure the likelihood of some strategies and tactics associated with improved well-being in attempting to reduce symptoms of anxiety.

This study measured the practice of …

Co-Option Of The Yolkless Oocyte Receptor For Crispr/Cas9 May Induce Transient Sterility In Female Drosophila Grimshawi Flies, Bronwyn Miller

LSU New Orleans Theses and Dissertations

Evolutionary developmental biology has historically used generalist model organisms like Drosophila melanogaster. The Hawaiian Drosophilidae radiation, which occurred just 25 million years ago, is an ideal lineage for work in Evo-Devo. Hawaiian flies make up 25% of the world’s Drosophila species and extreme diversity is seen throughout the group. D. grimshawi is a generalist Hawaiian picture-wing fly that has served as a model for the Hawaiian Drosophilidae radiation. However, D. grimshawi’s power and use as a model organism is constrained by our lack of ability to manipulate its genome. In this work, I attempted to edit the genome of …