Digital Commons Network^™

Supporting The Performance Of Noongar Language In Hecate, Clint Bracknell, Kylie Bracknell, Susan F. Studham, Luzita Fereday

Research outputs 2014 to 2021

As the first adaptation of a complete Shakespearean work presented entirely in one Aboriginal language of Australia, Hecate is a landmark production in Australian theatre. The Noongar language of the southwest of Western Australia is a critically endangered language impacted by colonisation since the early 1800s and suppressed until the 1970s. Working with an all-Noongar cast learning what is by birthright their mother-tongue, the Noongar language, on a full Shakespearean work presents a range of challenges. Consideration of effective rehearsal strategies to support brave spaces for the cast to flourish holistically, both as language learners and performers, was imperative. As …

Development And Validation Of The Holistic Cognition Scale, Andrei A. Lux, Steven L. Grover, Stephen T. Teo

Research outputs 2014 to 2021

This paper introduces a new scale to measure cognitive cultural differences, drawing on the theory of analytic versus holistic thought. Examining culture from a cognitive perspective is a challenge to traditional values-based approaches. Existing measures based on this framework are methodologically problematic and warrant renewal. This paper presents development and validation studies for a new instrument that measures analytic versus holistic cognitive tendencies at the individual level. The scale assesses four previously established dimensions: attention, causality, contradiction, and change. The present work follows well-established scale development protocols and the results show that the 16-item Holistic Cognition Scale (HCS) is a …

Evidence Of Large Increases In Sedimentation Rates Due To Fish Trawling In Submarine Canyons Of The Gulf Of Palermo (Sw Mediterranean), Sarah Paradis, Claudio Lo Iacono, Pere Masqué, Pere Puig, Albert Palanques, Tommaso Russo, The Island Cruise Tem

Research outputs 2014 to 2021

Bottom trawling in submarine canyons can affect their natural sedimentation rates, but studies addressing this issue are still scarce. In the Gulf of Palermo (SW Mediterranean), bottom trawling occurs on the slope around Oreto, Arenella and Eleuterio canyons. Analyses of excess 210Pb concentrations and grain size fractions in sediment cores from their canyon axes revealed that sedimentation rates and silt contents increased in all canyons in the 1980s, due to the expansion of more powerful trawlers ( > 500 HP) to deeper fishing grounds. In Eleuterio and Arenella canyons, sedimentation rates increased by an order of magnitude (0.1-1.4 cm·yr-1), whereas they …

No Casual Relationship Between T2dm And The Risk Of Infectious Diseases: A Two-Sample Mendelian Randomization Study, Huachen Wang, Zheng Guo, Yulu Zheng, Chunyan Yu, Haifeng Hou, Bing Chen

Research outputs 2014 to 2021

Background: In epidemiological studies, it has been proven that the occurrence of type 2 diabetes mellitus (T2DM) is related to an increased risk of infectious diseases. However, it is still unclear whether the relationship is casual. Methods: We employed a two-sample Mendelian randomization (MR) to clarify the causal effect of T2DM on high-frequency infectious diseases: sepsis, skin and soft tissue infections (SSTIs), urinary tract infections (UTIs), pneumonia, and genito-urinary infection (GUI) in pregnancy. And then, we analyzed the genome-wide association study (GWAS) meta-analysis of European-descent individuals and conducted T2DM-related single-nucleotide polymorphisms (SNPs) as instrumental variables (IVs) that were associated with …

Effect Of Co2 Flooding On The Wettability Evolution Of Sand-Stone, Cut Aja Fauziah, Ahmed Al-Yaseri, Emad Al-Khdheeawi, Nilesh Kumar Jha, Hussein R. Abid, Stefan Iglauer, Christopher Lagat, Ahmed Barifcani

Research outputs 2014 to 2021

Wettability is one of the main parameters controlling CO₂ injectivity and the movement of CO₂ plume during geological CO₂ sequestration. Despite significant research efforts, there is still a high uncertainty associated with the wettability of CO₂/brine/rock systems and how they evolve with CO₂ exposure. This study, therefore, aims to measure the contact angle of sandstone samples with varying clay content before and after laboratory core flooding at different reservoir pressures, of 10 MPa and 15 MPa, and a temperature of 323 K. The samples’ microstructural changes are also assessed to investigate any potential alteration …

Profile Of Immunoglobulin G N-Glycome In Covid-19 Patients: A Case-Control Study, Haifeng Hou, Huan Yang, Pengcheng Liu, Changwu Huang, Meng Wang, Yuejin Li, Mingsong Zhu, Jing Wang, Yuan Xu, Youxin Wang, Qingwei Ma, Dong Li, Pu Liao, Wei Wang

Research outputs 2014 to 2021

Coronavirus disease 2019 (COVID-19) remains a major health challenge globally. Previous studies have suggested that changes in the glycosylation of IgG are closely associated with the severity of COVID-19. This study aimed to compare the profiles of IgG N-glycome between COVID-19 patients and healthy controls. A case-control study was conducted, in which 104 COVID-19 patients and 104 age- and sex-matched healthy individuals were recruited. Serum IgG N-glycome composition was analyzed by hydrophilic interaction liquid chromatography with the ultra-high-performance liquid chromatography (HILIC-UPLC) approach. COVID-19 patients have a decreased level of IgG fucosylation, which upregulates antibody-dependent cell cytotoxicity (ADCC) in …

A Delirium Prevalence Audit And A Pre And Post Evaluation Of An Interprofessional Education Intervention To Increase Staff Knowledge About Delirium In Older Adults, Bev Ewens, Karla Seaman, Lisa Whitehead, Mandy Towell-Barnard, Michelle Young

Research outputs 2014 to 2021

Background

Delirium is more prevalent in older people and estimated to occur in up to 50% of the hospital population. Delirium comprises a spectrum of behaviours, including cognitive and attention deficits, and fluctuating levels of consciousness, often associated with an underlying physiological disturbance. Delirium has been increasingly associated with adverse outcomes. Although often preventable or can at least be mitigated, delirium may not be a standard part of assessment and thus may not be recognized in the early stages when it is most likely to be treated successfully. The aim of this study was to evaluate the level of knowledge …

Whole Fat Dairy Products Do Not Adversely Affect Adiposity Or Cardiometabolic Risk Factors Inchildren In The Milky Way Study: A Double Blind Randomized Controlled Pilot Study, Analise Nicholl, Kane Deering, Kate J. Evelegh, Philippa Lyons-Wall, David Lawrence, Trevor A. Mori, Mario Kratz, Therese O'Sullivan

Research outputs 2014 to 2021

Background

Limited evidence supports the common public health guideline that children > 2 y of age should consume dairy with reduced fat content.

Objectives

We aimed to investigate the effects of whole-fat compared with reduced-fat dairy intake on measures of adiposity and biomarkers of cardiometabolic risk in healthy 4- to 6-y-old children.

Methods

The Milky Way Study enrolled 49 children (mean ± SD age: 5.2 ± 0.9 y; 47% girls) who were habitual consumers of whole-fat dairy, then randomly assigned them in a double-blind fashion to remain on whole-fat dairy or switch their dairy consumption to reduced-fat products for 3 mo. …

Heritability Enrichment Of Immunoglobulin G N-Glycosylation In Specific Tissues, Xingang Li, Hao Wang, Yahong Zhu, Weijie Cao, Song Manshu, Youxin Wang, Haifeng Hou, Minglin Lang, Xiuhua Guo, Xuerui Tan, Jingdong J. Han, Wei Wang

Research outputs 2014 to 2021

Genome-wide association studies (GWAS) have identified over 60 genetic loci associated with immunoglobulin G (IgG) N-glycosylation; however, the causal genes and their abundance in relevant tissues are uncertain. Leveraging data from GWAS summary statistics for 8,090 Europeans, and large-scale expression quantitative trait loci (eQTL) data from the genotype-tissue expression of 53 types of tissues (GTEx v7), we derived a linkage disequilibrium score for the specific expression of genes (LDSC-SEG) and conducted a transcriptome-wide association study (TWAS). We identified 55 gene associations whose predicted levels of expression were significantly associated with IgG N-glycosylation in 14 tissues. Three working scenarios, i.e., tissue-specific, …

Organizational Factors Associated With Health Worker Protection During The Covid-19 Pandemic In Four Provinces Of South Africa, Muzimkhulu Zungu, Kuku Voyi, Nosimilo Mlangeni, Saiendhra Vasudevan Moodley, Jonathan Ramodike, Nico Claassen, Elizabeth Wilcox, Nkululeko Thunzi, Annalee Yassi, Jerry Spiegel, Molebogeng Malotle

Research outputs 2014 to 2021

Background: Health workers, in short supply in many low-and-middle-income countries, are at increased risk of SARS-CoV-2 infection. This study aimed to assess how South Africa, prepared to protect its health workers from SARS-CoV-2 infection. Methods: This was a cross-sectional study design applying participatory action research in four provinces of South Africa. A semi-structured questionnaire and a qualitative observational HealthWISE walkthrough risk assessment was carried out to collect data on occupational safety and health (OSH) systems in 45 hospitals across four provinces to identify factors associated with health worker protection. Adapting the International Labour Organization (ILO) and World Health Organization (WHO) …

‘Believe In Me, And I Will Too’: A Study Of How Teachers’ Expectations Instilled Confidence In Grade 10 Students, Olivia Johnston, Helen Wildy, Jennifer Shand

Research outputs 2014 to 2021

Teacher expectation research has continued to establish an association between what teachers expect of their students and what students accomplish academically. These expectations affect students when they are communicated by teachers through differential treatment in the class, but no qualitative research has sought adolescent students’ points of view about how they experience teacher expectation effects. This paper presents new research findings that explain how Grade 10 students experienced their teachers’ expectations in ways that they reflected impacted their academic outcomes. Classic grounded theory methods were used to develop this new knowledge, which has implications for how teachers are educated for, …

Short Word-Length Entering Compressive Sensing Domain: Improved Energy Efficiency In Wireless Sensor Networks, Nuha A. S. Alwan, Zahir M. Hussain

Research outputs 2014 to 2021

This work combines compressive sensing and short word-length techniques to achieve localization and target tracking in wireless sensor networks with energy-efficient communication between the network anchors and the fusion center. Gradient descent localization is performed using time-of-arrival (TOA) data which are indicative of the distance between anchors and the target thereby achieving range-based localization. The short word-length techniques considered are delta modulation and sigma-delta modulation. The energy efficiency is due to the reduction of the data volume transmitted from anchors to the fusion center by employing any of the two delta modulation variants with compressive sensing techniques. Delta modulation allows …

Improving Basalt Wettability To De-Risk Co2 Geo-Storage In Basaltic Formations, Stefan Iglauer, Ahmed Al-Yaseri

Research outputs 2014 to 2021

CO₂ geo-storage in basaltic formations has recently been identified as a viable option to rapidly dispose large quantities of CO₂, hence mitigating anthropogenic CO₂ emissions. However, it has been shown that basalt is weakly water-wet or intermediate-wet at typical storage conditions, which reduces capillary trapping capacities and increases lateral and vertical spreading of the CO₂ plume; and these effects increase project risk. We thus propose here to prime basalt surfaces with anionic surfactant (here we used sodium dodecyl benzene sulfonate), and demonstrate that such priming is highly efficient, and renders the basalt completely water-wet even …

Principle-Based Concept Analysis Methodology Using A Phased Approach With Quality Criteria, Stephanie Smith, Evalotte Mörelius

Research outputs 2014 to 2021

The study aimed to provide a detailed description of a process to conduct a phased principle-based concept analysis and to introduce quality criteria assessment for a phased principle-based concept analysis. Concept analysis explores how a concept is described, used and measured in the literature. This conceptual understanding is important to guide translational research to direct the development of evidence-based practice. The principle-based concept analysis is one approach of concept analysis used in published work, but the literature is lacking in articles clearly describing how to conduct it in practice. This article provides a methodology utilising a phased approach and by …

Stock Split Rule Changes And Stock Liquidity: Evidence From Bursa Malaysia, S. Amir Tabibian, Zhaoyong Zhang, Abdollah Ah Mand

Research outputs 2014 to 2021

We test the impact of stock split rule changes on liquidity behavior in Bursa Malaysia during 2004–2020. Using event study methodology, this study examines stock liquidity on and around stock split days through three subperiods of study, including the first (2004–2006), second (2007–2009), and third (2010–2020) period. We find that liquidity improvement is short-lived in the first and second periods, while it is a long-lived phenomenon in the third period. Firms in the first and second period experienced liquidity improvement only on the split announcement day, while it lasts up to a year after the Ex-date for firms in the …

Segregation Analysis Of Genotyped And Family-Phased, Long Range Mhc Classical Class I And Class Ii Haplotypes In 5 Families With Type 1 Diabetes Proband In The United Arab Emirates, Guan K. Tay, Halima Al Naqbi, Aurélie Mawart, Zahrah Baalfaqih, Anoud Almaazmi, Asma Deeb, Habiba Alsafar

Research outputs 2014 to 2021

The classical Human Leucocyte Antigen (HLA) class II haplotypes of the Major Histocompatibility Complex (MHC) that are associated with type 1 diabetes (T1D) were identified in five families from the United Arab Emirates (UAE). Segregation analyses were performed on these 5 families with the disease, 3 with one child and 2 with 2 children diagnosed with T1D. Three HLA-DR4 haplotypes were identified: HLA- DRB1∗04:01:01-DQB1∗03:02:01:01; HLA- DRB1∗04:02:01- DQB1∗03:02:01; and HLA -DRB1∗04:05:01-DQB1∗02:02:01:02. All have previously been identified to be associated with T1D in studies of the Arabian population. In the 10 parents from the 5 families, 9 had at least one HLA-DR4 …

Assessing The Applicability Of Three Approaches To Design-Oriented Research, Jing Zhou, Christopher Kueh, Yi Lin

Research outputs 2014 to 2021

The three main approaches in inquisitive research design are qualitative, quantitative, and mixed methods [1]. However, recent developments in the research field have resulted in multiple other approaches, borrowing ideas from a broad range of fields. One such approach is the practice-led approach. This approach involves an efficient design process, novel qualitative interviewing methods, together with data mining procedures from quantitative data collection [2]. This paper assesses the practice-led approach used in user experience (UX) design, together with three approaches: co-design, service design, and reflective practice.

A Range Error Reduction Technique For Positioning Applications In Sports, Adnan Waqar, Iftekhar Ahmad, Daryoush Habibi, Quoc V. Phung

Research outputs 2014 to 2021

In recent times, ultra-wideband (UWB)-based positioning systems have become popular in sport performance monitoring. UWB positioning system uses time of arrival to calculate the range data between devices (i.e. anchors, tags), and then use trilateration algorithms to estimate position coordinates. In practical applications, non-line-of-sight transmissions and multipath propagations lead to inaccurate range data and lower positioning accuracy. This paper introduces a range error minimisation algorithm to address this limitation of error in range data in UWB-based positioning system. The proposed solution analyses the range error for each anchor and sequentially reduces this error based on the distance between each anchor …

Designing Call To Action: Users' Perception Of Different Charateristics, Thomas Mejtoft, Jonathan Hedlund, Helen Cripps, Ulrik Söderström, Ole Norberg

Research outputs 2014 to 2021

This paper aims to provide guidance when designing a call to action in a digital system with the purpose to create an intended feeling and user engagement. The paper is based on a test of four different simple call to action constructions. The users clearly prefer constructions that have a high explainability and feels intuitive. Hence, the design should have a high level of transparency and show the user straight away what it demands from the user and what the result of the action is. Furthermore, the design should have a high usability to make it clear how to use …

Physicochemical Characterisation Of Zirconia Nanoparticles Based Sodium Alginate Polymer Suspension For Enhanced Oil Recovery, Udit S. Mohanty, Faisal Ur Rahman Awan, Muhammad Ali, Adnan Aftab, Alireza Keshavarz, Sefan Iglauer

Research outputs 2014 to 2021

Biopolymers have been employed in enhanced oil recovery (EOR) due to their high viscosity and significant effects on waterflooding performance. Sodium alginate (NaAlg) is an excellent biopolymer that is extracted primarily from brown algae. It has been used in the biotechnology industry as a thickening agent, colloidal stabilizer, and oil recovery application. In the present study, a series of sodium alginate/zirconium oxide nanoparticle suspensions were prepared via solution mixing, and the effect of nanoparticle content, polymer concentration, temperature, salinity was investigated on the rheological behavior using a concentric cylinder dynamic rheometer. The rheology results revealed that the lower concentration of …

Association Of Genetic Variants With Prostate Cancer In Africa: A Concise Review, Emmanuel Acheampong, Evans A. Adu, Christian Obirikorang, George Amoah, Osei O. Afriyie, Joseph Yorke, Enoch O. Anto, Michael A. Gyamfi, Emmanuella N. Acheampong, Christian K. Gyasi-Sarpong, Francis A. Yeboah

Research outputs 2014 to 2021

Background: Prostate cancer (PCa) has one of the highest heritability of all major cancers, where the genetic contribution has been documented, and knowledge about the molecular genetics of the disease is increasing. However, the extent and aspects to which genetic variants explain PCa heritability in Africa are limited. Main body: In this review, we summarize studies that highlight how identified genetic variants explain differences in PCa incidence and presentation across ethnic groups. We also present the knowledge gaps in PCa genetics in Africa and why Africa represents an untapped potential ground for genetic studies on PCa. A significant number of …

Infrequent Pattern Detection For Reliable Network Traffic Analysis Using Robust Evolutionary Computation, A. N. M. Bazlur Rashid, Mohiuddin Ahmed, Al-Sakib K. Pathan

Research outputs 2014 to 2021

While anomaly detection is very important in many domains, such as in cybersecurity, there are many rare anomalies or infrequent patterns in cybersecurity datasets. Detection of infrequent patterns is computationally expensive. Cybersecurity datasets consist of many features, mostly irrelevant, resulting in lower classification performance by machine learning algorithms. Hence, a feature selection (FS) approach, i.e., selecting relevant features only, is an essential preprocessing step in cybersecurity data analysis. Despite many FS approaches proposed in the literature, cooperative co-evolution (CC)-based FS approaches can be more suitable for cybersecurity data preprocessing considering the Big Data scenario. Accordingly, in this paper, we have …

Validation Of Fatty Liver Disease Scoring Systems For Ultrasound Diagnosed Non-Alcoholic Fatty Liver Disease In Adolescents, Fuzhen Wan, Feng Pan, Oyekoya T. Ayonrinde, Leon A. Adams, Trevor A. Mori, Lawrence J. Beilin, Therese A. O'Sullivan, John K. Olynyk, Wendy H. Oddy

Research outputs 2014 to 2021

Background and Aims: The incidence of non-alcoholic fatty liver disease (NAFLD) is increasing in young populations. However, there are inadequate data regarding diagnosis of NAFLD. We aimed to validate three scoring systems against a previous standard of suprailiac skinfold thickness for diagnosing NAFLD in population-based adolescents.

Methods: Seventeen-year-old adolescents (n = 899), participating in the Raine Study, attended a cross-sectional follow-up. NAFLD was diagnosed using liver ultrasound. Scores for Fatty liver index (FLI), Hepatic Steatosis Index (HSI) and Zhejiang University index (ZJU index) were calculated. Diagnostic accuracy of these diagnostic tests was evaluated through discrimination and calibration.

Results: NAFLD …

Collaboration And Opportunism In Megaproject Alliance Contracts: The Interplay Between Governance, Trust And Culture, Peter Galvin, Stephane Tywoniak, Janet Sutherland

Research outputs 2014 to 2021

Alliance contracts have been introduced in megaprojects to improve the alignment of objectives, risk and reward between client and contractor. However, the relational norms of alliances are not sufficient on their own to eliminate opportunistic behaviors. This study shows that, investing in mechanisms supportive of governance, culture, and trust provides a platform upon which firms may foster collaboration and limit self-interest oriented behavior amongst alliance partners. Our qualitative case study of a major project-based organization reveals the impact of these mechanisms, and more pointedly, how they interact and often reinforce each other. Governance, culture and trust are interlinked and complementary, …

Educative Power And The Respectful Curricular Inclusion Of Aboriginal And Torres Strait Islander Music, Michael Webb, Clint Bracknell

Research outputs 2014 to 2021

This chapter argues for the full, respectful curricular inclusion of Aboriginal and Torres Strait Islander music in order to promote a more balanced and equitable social and cultural vision of the nation-state in Australian schools. It challenges views that claim Indigenous cultures have been irretrievably lost or are doomed to extinction, as well as the fixation on musical authenticity. We propose that the gradual broadening of Indigenous musical expressions over time and the musical renaissance of the new millennium have created an unprecedented opportunity for current music educators to experience the educative power of Aboriginal and Torres Strait Islander music. …

Digital Forensic Readiness Intelligence Crime Repository, Victor R. Kebande, Nickson M. Karie, Kim-Kwang R. Choo, Sadi Alawadi

Research outputs 2014 to 2021

It may not always be possible to conduct a digital (forensic) investigation post-event if there is no process in place to preserve potential digital evidence. This study posits the importance of digital forensic readiness, or forensic-by-design, and presents an approach that can be used to construct a Digital Forensic Readiness Intelligence Repository (DFRIR). Based on the concept of knowledge sharing, the authors leverage this premise to suggest an intelligence repository. Such a repository can be used to cross-reference potential digital evidence (PDE) sources that may help digital investigators during the process. This approach employs a technique of capturing PDE from …

Association Of Β-Amyloid Level, Clinical Progression And Longitudinal Cognitive Change In Normal Older Individuals, Laura M. Van Der Krall, Thanh Truong, Samantha C. Burnham, Vincent Doré, Rachel S. Mulligan, Svetlana Bozinovski, Fiona Lamb, Pierrick Bourgeat, Jurgen Fripp, Stephanie Schultz, Yen Y. Lim, Simon M. Laws, David Ames, Christopher Fowler, Stephanie R. Rainey-Smith, Ralph N. Martins, Olivier Salvado, Joanne Robertson, Paul Maruff, Colin L. Masters, Victor L. Villemagne, Christopher C. Rowe

Research outputs 2014 to 2021

Objective To determine the effect of β-amyloid (Aβ) level on progression risk to mild cognitive impairment (MCI) or dementia and longitudinal cognitive change in cognitively normal (CN) older individuals. Methods All CN from the Australian Imaging Biomarkers and Lifestyle study with Aβ PET and ≥ 3 years follow-up were included (n = 534; age 72 ± 6 years; 27% Aβ positive; follow-up 5.3 ± 1.7 years). Aβ level was divided using the standardized 0–100 Centiloid scale: < 15 CL negative, 15–25 CL uncertain, 26–50 CL moderate, 51–100 CL high, > 100 CL very high, noting > 25 CL approximates a positive scan. Cox proportional hazards analysis and linear mixed effect models were used to assess …

A Narrative Review Of The Pharmacological, Cultural And Psychological Literature On Ibogaine, Martie S. Underwood, Stephen J. Bright, B. Les Lancaster

Research outputs 2014 to 2021

Ibogaine is a psychoactive alkaloid contained in the West African plant Tabernanthe iboga. Although preliminary, evidence suggests that ibogaine could be effective in the treatment of certain substance use disorders, specifically opioid use disorder. This narrative review concentrated on the pharmacological, cultural and psychological aspects of ibogaine that contribute to its reputed effectiveness with a specific focus on the ibogaine state of consciousness. Although the exact pharmacological mechanisms for ibogaine are still speculative, the literature highlighted its role as an NMDA antagonist in the effective treatment of substance use disorders. The cultural aspects associated with the use of ibogaine pose …

Heterogeneous Tidal Marsh Soil Organic Carbon Accumulation Among And Within Temperate Estuaries In Australia, Connor Gorham, Paul S. Lavery, Jeffrey J. Kelleway, Pere Masque, Oscar Serrano

Research outputs 2014 to 2021

The scarcity of data on tidal marsh soil accumulation rates (SAR) and soil organic carbon accumulation rates (CAR) globally precludes a comprehensive assessment of the role of tidal marshes in climate change mitigation and adaptation. Particularly few data exist from the southern hemisphere and for Australia in particular, which contains ~24% of globally recognised tidal marsh extent. Here we estimate SAR and CAR over the last 70 years using 210Pb-based geochronologies in temperate estuarine tidal marsh ecosystems in southern Western Australia (WA). Specifically, we assessed tidal marsh ecosystems situated in two geomorphic settings (marine vs. fluvial deltas) within 10 wave-dominated, …

Communication Surrounding Initiation And Withdrawal Of Non-Invasive Ventilation In Adults With Motor Neuron(E) Disease: Clinicians’ And Family Members’ Perspectives, Charlotte Chapman, Sara Bayes, Moira Sim

Research outputs 2014 to 2021

Introduction: International guidelines recommend that health care clinicians communicate with people with MND and their family members about non-invasive ventilation (NIV) and percutaneous gastrostomy tube (PEG) prior to or at the onset of respiratory symptoms. This study sought to discover the degree to which these recommendations are followed in practice.

Methods: Interpretive Description methodology was employed. Nineteen clinicians experienced in caring for people with MND, six relatives of recently deceased people with MND and one person with MND participated in semi-structured in-depth interviews. Clinicians’ accounts of NIV and PEG related communications were compared to family member participants’ recollections of their …