Open Access. Powered by Scholars. Published by Universities.®

Digital Commons Network™

Open Access. Powered by Scholars. Published by Universities.®

2021

Discipline
Institution
Keyword
Publication
Publication Type
File Type

Articles 93811 - 93840 of 96330

Full-Text Articles in Entire DC Network

Humanistic Stem: From Concept To Course, Debra T. Bourdeau, Beverly L. Wood Jan 2021

Humanistic Stem: From Concept To Course, Debra T. Bourdeau, Beverly L. Wood

Publications

Blending perspectives from the humanities and STEM fosters the creativity of all students. The culturally implicit dichotomy between the two meta-disciplines can be overcome with carefully designed courses and programs intent on doing so. The why and how of doing so through an online course is described with qualitative evidence of the success. Future plans for a full slate of such course and a virtual community are discussed.


Exploiting Semantic Embedding And Visual Feature For Facial Action Unit Detection, Huiyuan Yang, Lijun Yin, Yi Zhou, Jiuxiang Gu Jan 2021

Exploiting Semantic Embedding And Visual Feature For Facial Action Unit Detection, Huiyuan Yang, Lijun Yin, Yi Zhou, Jiuxiang Gu

Computer Science Faculty Research & Creative Works

Recent study on detecting facial action units (AU) has utilized auxiliary information (i.e., facial landmarks, relationship among AUs and expressions, web facial images, etc.), in order to improve the AU detection performance. As of now, no semantic information of AUs has yet been explored for such a task. As a matter of fact, AU semantic descriptions provide much more information than the binary AU labels alone, thus we propose to exploit the Semantic Embedding and Visual feature (SEV-Net) for AU detection. More specifically, AU semantic embeddings are obtained through both Intra-AU and Inter-AU attention modules, where the Intra-AU attention module …


Mindfulness Training In Emergency Department Nurses: Review Of Literature, Amy Newstrom Jan 2021

Mindfulness Training In Emergency Department Nurses: Review Of Literature, Amy Newstrom

Doctor of Nursing Practice (DNP) Practice Innovation Projects

Introduction: Compassion fatigue is prevalent among nurses. Nurses and patients are negatively impacted by the occurrence of compassion fatigue. Research has indicated that nurses working in high-acuity areas, such as the emergency department, are more likely to experience compassion fatigue. Mindfulness training has been shown to reduce symptoms of compassion fatigue. The goal of this project was to examine the effect of mindfulness training on Professional Quality of Life V (ProQOL-V-V) subscale scores.
Evidence Summary: An evidence search was conducted using the EBSCO Megafile, CINAHL, APA PsychArticles, and APA PsychInfo databases. Keywords: Professional Quality of Life, Maslach Burnout Inventory, Oldenburg …


Education On My Healthevet To Increase Access To Psychiatric Healthcare For Veterans, Roxann Hackbarth Jan 2021

Education On My Healthevet To Increase Access To Psychiatric Healthcare For Veterans, Roxann Hackbarth

Doctor of Nursing Practice (DNP) Practice Innovation Projects

Introduction: Access to mental health care can be challenging for many veterans. The Veterans Health Administration (VHA) developed the patient portal My Healthevet (MHV) to increase access to healthcare services. Despite this program, many veterans still do not take advantage of the portal. The goal of this literature review was to gain knowledge on benefits and barriers of using patient portals, identification of patients who use and do not use patient portals, and interventions to increase the use of patient portals.
Evidence Summary: The use of patient portals, including the VHA portal MHV, helps to increase interactions between clinicians and …


Effect Of Emergency Severity Index (Esi) Annual Competency Assessment On Mistriage Rates, Stefanie Hoffman Jan 2021

Effect Of Emergency Severity Index (Esi) Annual Competency Assessment On Mistriage Rates, Stefanie Hoffman

Doctor of Nursing Practice (DNP) Practice Innovation Projects

Introduction: In order to accurately assign an Emergency Severity Index (ESI) acuity level to patients who present to the emergency department (ED) triage area, it is essential triage nurses remain competent in the ESI triage tool. In addition, effective use of the ESI triage tool is critical in preventing patients from being mistriaged.
Objective: The purpose of this quality improvement project was to determine the effect of an ESI annual competency assessment in an ED for triage trained registered nurses (RNs).
Methods: Triage trained RNs completed an ESI competency assessment composed of 25 patient scenarios in competency assessment A, and …


Opioid Overdose Response Teaching To Staff In A Homeless Shelter, Hayley E. Rasmussen Jan 2021

Opioid Overdose Response Teaching To Staff In A Homeless Shelter, Hayley E. Rasmussen

Doctor of Nursing Practice (DNP) Practice Innovation Projects

Background/Purpose: Opioid overdose can occur in anyone who uses illicit drugs, but relationship correlation exists between homelessness and illicit drug use. Between March 2019 and March 2020, 92 deaths were attributed to opioids in the DNP Project state. Methods: Naloxone education was given to a single population of homeless shelter staff. An Opioid Overdose Attitude Scale (OOAS) and Opioid Overdose Knowledge Scale (OOKS) were administered to the sample prior to education, immediately after education, and 3 months after education.
Results: OOAS and OOKS changes between surveys as a whole were not statistically significant (p=0.14; p=0.25). Individual components of the surveys …


Effect Of Yoga On Nurse Burnout, Marie Schone Jan 2021

Effect Of Yoga On Nurse Burnout, Marie Schone

Doctor of Nursing Practice (DNP) Practice Innovation Projects

Background: Burnout is the result of emotional exhaustion (EE), depersonalization (DP), and decreased personal accomplishments (PA). When burnout is experienced, it can create an unhealthy environment for the nurses and patients. Methods: Nurses participated in an eight-week yoga course which focused on hatha yoga practices to teach postural alignment, relaxation and meditation, mindfulness, and selfawareness. Those who participated completed the Maslach Burnout Inventory (MBI) questionnaire pre- and post-intervention to measure burnout levels. Results: The paired sample t-test with a 5% level of significance found a statistically significant reduction in EE (p = 0.0001) and DP (p = 0.0074) subscale score …


Evaluation Of Robust Epoxy Resin Sealants For Wellbore Integrity Applications, Mohammed Mousa M Alkhamis Jan 2021

Evaluation Of Robust Epoxy Resin Sealants For Wellbore Integrity Applications, Mohammed Mousa M Alkhamis

Doctoral Dissertations

"During the drilling and completion phases of oil and gas wells, cement is placed in the wellbore as a barrier between the casing and the formation. All casing strings must be cemented to protect and support the casing, and to isolate production zones. The primary cement must prevent the wellbore fluids from migrating in an annular flow path so as to allow the wells to be utilized without any control problems. The primary cement may fail to deliver full zonal isolation due to several reasons such as insufficient mud removal before the cementing, casing expansion, and contraction, high fluid losses, …


Investigating The Effect Of Operating Condition On Esd-Induced Soft-Failures, Omid Hoseini Izadi Jan 2021

Investigating The Effect Of Operating Condition On Esd-Induced Soft-Failures, Omid Hoseini Izadi

Doctoral Dissertations

"Conflicting observations have been found in the literature regarding the effect of operating conditions on ESD (electrostatic discharge) susceptibility. While some studies have suggested a strong correlation between the two, others observed little to no correlation. In this work, a systematic study has been carried out suggesting the existence of a strong correlation between the ESD susceptibility and operating conditions. It is found that the root cause of this conflict is random ESD noise injection. A measurement approach is proposed to synchronize the noise injection with the system activity such as high/low CPU load. In this approach, the current consumption …


Integrated Solar And Ess Ac/Dc Systems For Various Grid Applications, Phani Ratna Vanamali Marthi Jan 2021

Integrated Solar And Ess Ac/Dc Systems For Various Grid Applications, Phani Ratna Vanamali Marthi

Doctoral Dissertations

"Modular multilevel converters (MMC) have gained prominence for high power applications in recent years due to their technical merits such as voltage scalability, harmonic performance, and high efficiency. Integration of renewable energy sources such as solar photovoltaic (PV) systems and energy storage systems (ESS) to the grid using power electronic (PE) resources is increasing due to the techno-economic successes achieved by such systems. Following these developments, the integration of MMCs with PV plants and ESS systems is one of the dynamic research avenues being pursued. Along these lines, an integrated development of PV plants, ESS, and alternating- and direct-current (ac/dc) …


Scheduling Based Optimization In Software Defined Radio And Wireless Networks, Nathan Daniel Price Jan 2021

Scheduling Based Optimization In Software Defined Radio And Wireless Networks, Nathan Daniel Price

Doctoral Dissertations

"The objective of this work is to enable dynamic sharing of software-defined radio (SDR) transceivers through the concepts of hardware virtualization and real-time resource management. SDR is a way to build a digital radio that consists of a software back-end for digital signal processing (DSP) and an analog front-end transceiver for waveform generation and reception. This work proposes the use of a virtualization layer to decouple back-end SDR software from front-end transceivers. With this arrangement, front-ends are said to be virtualized, and it becomes possible to share a limited number of front-ends among many SDR back-ends through different multiplexing techniques. …


Thermophysical Properties Of Nominally Phase Pure Boride Ceramics, Austin D. Stanfield Jan 2021

Thermophysical Properties Of Nominally Phase Pure Boride Ceramics, Austin D. Stanfield

Doctoral Dissertations

"This research focusses on the thermophysical properties of nominally phase pure boride ceramics. As interest in ultra high temperature ceramics increases due to a renewed interest in hypersonic flight vehicles and with the expanding materials design space accompanying interest in high entropy materials, it is imperative to understand the intrinsic properties of boride ceramics. By reducing Hf content in ZrB2 from the natural abundance, ~1.75 at% in this case, to ~100 ppm, thermal conductivity increased from 88 W/m·K to 141 W/m·K. Removal of Hf allowed the thermal conductivity of ZrB2 with small transition metal solute additions to be …


Fiber Optic Sensors For Industry And Military Applications, Yiyang Zhuang Jan 2021

Fiber Optic Sensors For Industry And Military Applications, Yiyang Zhuang

Doctoral Dissertations

"Fiber optic sensors (FOSs) have been widely used for measuring various physical and chemical measurands owing to their unique advantages over traditional sensors such as small size, high resolution, distributed sensing capabilities, and immunity to electromagnetic interference. This dissertation focuses on the development of robust FOSs with ultrahigh sensitivity and their applications in industry and military areas.

Firstly, novel fiber-optic extrinsic Fabry-Perot interferometer (EFPI) inclinometers for one- and two-dimensional tilt measurements with 20 nrad resolution were demonstrated. Compared to in-line fiber optic inclinometers, an extrinsic sensing motif was used in our prototype inclinometer. The variations in tilt angle of the …


Improving Employee Engagement On An Inpatient Unit: A Quality Improvement Project, Holly Mccormack Jan 2021

Improving Employee Engagement On An Inpatient Unit: A Quality Improvement Project, Holly Mccormack

DNP Scholarly Projects

BACKGROUND: Engaged employees are paramount to the success of an organization. They are more invested in their organization and the unit on which they work. This investment in the organization results in higher patient satisfaction and safety, less staff turnover, and improved quality. According to the literature, generational differences may be necessary to consider when improving employee engagement. To successfully lead a multigenerational workforce, nurse leaders should consider these differences and incorporate them into their strategic plan for employee engagement.

METHODS: A pilot survey was conducted on a medical-surgical unit to assess a perceived lack of engagement. Subsequently, work engagement …


Improving The Diagnosis Of Major Depression In A Primary Care Practice Using The Patient Health-9 Questionnaire, Chukwudi C. Orji Jan 2021

Improving The Diagnosis Of Major Depression In A Primary Care Practice Using The Patient Health-9 Questionnaire, Chukwudi C. Orji

DNP Scholarly Projects

Abstract

Background: Major depression is a serious health problem that affects both children and adults. It is a leading cause of disability worldwide. Most cases of major depression are treated in primary care settings. Many cases of major depression presenting in primary care are missed. Many PCPs do not routinely use screening tools. The aim of this project is to improve the diagnosis of major depression in adults in a primary care practice through routine use of the Patient Health Questionnaire-9 (PHQ-9) during initial encounter with patients and during follow-up visit for patients who are receiving treatment for depression to …


Machine Learning For Measuring And Analyzing Online Social Communications, Chris Bronk, Amaury Lendasse, Peggy Lindner, Dan S. Wallach, Barbara Hammer Jan 2021

Machine Learning For Measuring And Analyzing Online Social Communications, Chris Bronk, Amaury Lendasse, Peggy Lindner, Dan S. Wallach, Barbara Hammer

Engineering Management and Systems Engineering Faculty Research & Creative Works

In This Paper, We Propose a Framework for Application of a Novel Machine Learning-Based System for Analyzing Online Social Communications. as an Example, We Are Targeting Anti-Semitic Graphical Memes Posted to Social Media. We Presented Very Promising Preliminary Results on a Facebook Dataset that Consists of a Total of 10000 Labeled Memes. We Can Conclude that Machine Learning Will Soon Be Able to Successfully Analyze and Monitor Complex Social Communications.


Open And Distance Learning Programs For Nursing And Midwifery Education In East Africa: Protocol For A Scoping Review, Kahabi Isangula, Grace Edwards, Tumbwene Mwansisya, Columba Mbekenga, Eunice Pallangyo, Ahmed Sarki, Eunice Ndirangu Jan 2021

Open And Distance Learning Programs For Nursing And Midwifery Education In East Africa: Protocol For A Scoping Review, Kahabi Isangula, Grace Edwards, Tumbwene Mwansisya, Columba Mbekenga, Eunice Pallangyo, Ahmed Sarki, Eunice Ndirangu

School of Nursing & Midwifery, East Africa

Background: In the face of growing modernity and the coronavirus disease 2019 (COVID-19) pandemic, open and distance learning (ODL) is considered to play an important role in increasing access to education worldwide. There is a robust evidence base demonstrating its cost effectiveness in comparison with conventional class-based teaching; however, the transition to this new paradigm of learning for nursing and midwifery courses has been difficult in low-income countries. While there are notable efforts to increase internet and education access to health care professionals, not much is known about ODL for nurses and midwives in East African countries.

Objective: The objective …


Social Influences And Social Desirability On Recollections Of Childhood Bullying, Jaynee L. Bohart Jan 2021

Social Influences And Social Desirability On Recollections Of Childhood Bullying, Jaynee L. Bohart

Graduate Student Theses, Dissertations, & Professional Papers

Parents and peers play important roles in shaping attitudes toward a variety of matters during adolescence. However, little research has investigated parental and peer influence on developing attitudes toward bullying. Further, few studies have looked at whether socially desirable responding (SDR) impacts self-reports in bullying research. To address these gaps in literature, the current study recruited college students from a mid-sized public university in the Rocky Mountain region of the United States to complete a survey. The survey assessed the participants’ past attitudes toward bullying, perceptions of their parents’ and peers’ influence on their attitudes, and bullying participant roles during …


School Leadership Under Apartheid South Africa As Portrayed In The Apartheid Archive Projectand Interpreted Through Freirean Education, Kevin Bruce Deitle Jan 2021

School Leadership Under Apartheid South Africa As Portrayed In The Apartheid Archive Projectand Interpreted Through Freirean Education, Kevin Bruce Deitle

Graduate Student Theses, Dissertations, & Professional Papers

This qualitative study employed a phenomenological approach to examine how teachers, school leaders, and students rationalize their roles in the educational process when their institution is bounded by an educational system that openly strives against them. For a context, this study examined apartheid-era South Africa, from 1948 to 1994, which established social and administrative policies that deliberately curtailed the education of Indigenous and other South Africans, as a means of oppressing non-European ethnic groups.

In lieu of face-to-face interviews, stories and interviews submitted to The Apartheid Archive Project, curated by the University of the Witwatersrand, in Johannesburg, South Africa, portrayed …


Integrated Primary Care Is Associated With Greater Job Satisfaction And Less Burnout Among Montana’S Medical And Behavioral Health Care Providers, C. Ivie English Jan 2021

Integrated Primary Care Is Associated With Greater Job Satisfaction And Less Burnout Among Montana’S Medical And Behavioral Health Care Providers, C. Ivie English

Graduate Student Theses, Dissertations, & Professional Papers

Most research to date on integrated behavioral health (IBH) or integrated primary care (IPC) practices has examined primary care settings nested within academic medical centers or clinics within the U.S. Department of Veterans Affairs. This leaves clinics in rural and/or underserved communities without much representation in the literature. Likewise, provider job satisfaction and burnout have rarely been linked to the IPC model. Through an online cross-sectional survey of medical and behavioral health care providers in various primary care-based health care settings throughout Montana, this cross-sectional study demonstrates that degree of behavioral health integration significantly predicts greater job satisfaction and lower …


"Its Own Little City": Service Work In Truck Stops, Michelle Elizabeth Williams Jan 2021

"Its Own Little City": Service Work In Truck Stops, Michelle Elizabeth Williams

Graduate Student Theses, Dissertations, & Professional Papers

Montana truck stops act as a meeting place for long-haul truckers, vacationers, local commuters, and the workers simply trying to earn a living. The employees at such truck stops must navigate working-class customer service norms while interacting with a unique and diverse set of customers. The ethnographic and interview data that I collected during the 2020 offers a unique view of how customer service employees fared during political unrest, global health concerns, and financial struggle. Additionally, this study highlights the power dynamics that exist in the service industry by examining how such dynamics manifest in the interactions surrounding face masks, …


Leadership: Supporting Students With Asd And The School Wide Community, Chelsae Joy Larson Jan 2021

Leadership: Supporting Students With Asd And The School Wide Community, Chelsae Joy Larson

Graduate Student Theses, Dissertations, & Professional Papers

Leaders work collaboratively with all stakeholders to help understand what systems and supports need to be put into place to meet individual needs. School leaders must create continuous learning opportunities and reinforcement systems for educators in the areas of evidence-based practices, individualized teaching strategies, and student transition plans. Students with Autism Spectrum Disorder (ASD) require consistent and structured programming starting in preschool and carrying through to post-secondary education. It is imperative that school leaders provide the appropriate training and supports to educators and specialists in relation to executive functioning skills and evidence-based practices to best support students with ASD. This …


Reading The Bones: A Taphonomic Investigation Of Archaeofaunal Remains Recovered From Site 48pa551, Northwest Wyoming, Morgan H. Thurman Jan 2021

Reading The Bones: A Taphonomic Investigation Of Archaeofaunal Remains Recovered From Site 48pa551, Northwest Wyoming, Morgan H. Thurman

Graduate Student Theses, Dissertations, & Professional Papers

This is a preliminary taphonomy study of archaeofaunal remains found at site 48PA551, more commonly known as the Dead Indian Creek Site. 48PA551 is a well-known and commonly cited example of a McKean Complex occupation dating to between 3,800 and 4,800 B.P. The University of Montana held a field school at the site conducting small test excavations under the supervision of Dr. Anna Marie Prentiss in 2018. In the course of this testing a highly fragmentary bone bed consisting mostly of mammalian bone, cervids largely, was discovered eroding into the nearby creek. Ten 50 x 50 cm quadrants were excavated …


Summit Learning And Rural Montana Teacher Efficacy, A Phenomenology, C. Roch Turner Jan 2021

Summit Learning And Rural Montana Teacher Efficacy, A Phenomenology, C. Roch Turner

Graduate Student Theses, Dissertations, & Professional Papers

Following the global COVID-19 pandemic, schools across the United States experimented with online learning platforms. Prior to that, hundreds of schools adopted the Summit Learning platform, meant to supplement face-to-face learning with digital instruction and curricula. This study is a qualitative phenomenology exploring the lived experiences of teachers in two rural Montana schools that have adopted the Summit Learning platform and maintained its use into the pandemic. Participants of this study taught core courses, such as math, science, and history. Results of this study indicate a high level of curriculum modification and support from leadership. Participants reported modified changes to …


Pivoting To Deeper Experiences In Higher Education Classrooms, Danielle M. Pratt, Daniel W. Eadens Jan 2021

Pivoting To Deeper Experiences In Higher Education Classrooms, Danielle M. Pratt, Daniel W. Eadens

Faculty Scholarship and Creative Works

In higher education, pivoting quickly to a fully virtual experience online in the midst of a global pandemic is an adventure. There are marked differences between the online experience for a student who was already in a web-delivered course versus one that started face-to-face and quickly pivoted to an online setting. Some assignments, lessons, and courses are easily delivered in alternate formats while other learning opportunities are much more difficult to transition for online delivery. For example, assignments that involve internships or in-person experiences had to shift dramatically, be delayed, or cancelled. Beyond the experiences within the higher education classroom, …


Aquatic Locomotion In Birds – Biomechanics, Morphometrics, And Evolution, Anthony Barrett Lapansky Jan 2021

Aquatic Locomotion In Birds – Biomechanics, Morphometrics, And Evolution, Anthony Barrett Lapansky

Graduate Student Theses, Dissertations, & Professional Papers

The entire diversity of life on earth exists in air or water. Whether an organism lives in air or water provides the most fundamental description of its physical world and establishes an organism’s ecological niche on the most essential level. Because these two fluids are vastly different from one another, they also dictate, via the process of natural selection, the morphology and physiology of the organisms which call them home. By studying how organisms interact with these fluids – to locomote or obtain food, for example – we have the ability to not only link organism form and function, but …


An Interleaved Quadratic High Step-Up Dc-Dc Converter With Coupled Inductor, Ramin Rahimi, Saeed Habibi, Mehdi Ferdowsi, Pourya Shamsi Jan 2021

An Interleaved Quadratic High Step-Up Dc-Dc Converter With Coupled Inductor, Ramin Rahimi, Saeed Habibi, Mehdi Ferdowsi, Pourya Shamsi

Electrical and Computer Engineering Faculty Research & Creative Works

A new high step-up DC-DC converter for renewable energy applications is proposed in this paper. Employing an interleaved quadratic structure, two two-winding coupled inductors (CIs), and voltage multiplier cells (VMCs), the proposed converter can provide high-voltage gains, continuous input current with low ripple, reduced voltage stresses on semiconductors, common ground between input and output sides, and low numbers of components. In addition, diode-capacitor lossless clamp circuits are utilized to limit the voltage stresses of the power switches and further extend the voltage gain. The operating and steady-state analyses, design considerations, and a comparison with other previously published high step-up converters …


Artificial Neural Networks For Asymmetric Selective Harmonic Current Mitigation-Pwm In Active Power Filters To Meet Power Quality Standards, Amirhossein Moeini, Morteza Dabbaghjamanesh, Jonathan W. Kimball, Jie Zhang Jan 2021

Artificial Neural Networks For Asymmetric Selective Harmonic Current Mitigation-Pwm In Active Power Filters To Meet Power Quality Standards, Amirhossein Moeini, Morteza Dabbaghjamanesh, Jonathan W. Kimball, Jie Zhang

Electrical and Computer Engineering Faculty Research & Creative Works

The main objective of an active power filter (APF) is to control the harmonics of nonlinear loads in power systems. In addition, the reactive power (fundamental component of the AC power) at the point of common coupling (PCC) can be compensated by using an APF. This paper investigates a technique for the modulation technique of the active power filters. Using the artificial neural network (ANN) technique, real-time fundamental and harmonic compensations can be achieved for the low-frequency modulation techniques such as asymmetric selective harmonic elimination/mitigation-pulse width modulation (ASHE/ASHM-PWM) and asymmetric selective harmonic current mitigation-PWM (ASHCM-PWM). This means that different phases …


Hybrid Beamforming With Deep Learning For Large-Scale Antenna Arrays, Rentao Hu, Lijun Jiang, Ping Li Jan 2021

Hybrid Beamforming With Deep Learning For Large-Scale Antenna Arrays, Rentao Hu, Lijun Jiang, Ping Li

Electrical and Computer Engineering Faculty Research & Creative Works

The emergence of highly directional beamforming technology makes millimeter wave frequency band communication possible in future wireless communication networks. Based on the multipath characteristics of millimeter wave frequency communication, a high-precision multipath channel estimation algorithm based on signal subspace is proposed. In the mobile terminal, an iterative heuristic radiofrequency combination algorithm based on spatial points is proposed. The analog precoding at the base station uses deep learning to accelerate the calculation, and then the multi-user communication is modeled to design the digital precoding. The simulation results show that the multi-channel estimation algorithm can estimate 4 paths with an error of …


Quantitative Assessment Of Glioblastoma Phenotypes In Vitro Establishes Cell Migration As A Robust Readout Of Crk And Crkl Activity., Taeju Park, Neka Large, Tom Curran Jan 2021

Quantitative Assessment Of Glioblastoma Phenotypes In Vitro Establishes Cell Migration As A Robust Readout Of Crk And Crkl Activity., Taeju Park, Neka Large, Tom Curran

Manuscripts, Articles, Book Chapters and Other Papers

The expression levels of CT10 regulator of kinase (Crk) and Crk-like (CrkL) are elevated in many human cancers, including glioblastoma (GBM), and are believed to contribute to poor prognosis. Although Crk and CrkL have been proposed as therapeutic targets in these tumors, the lack of a reliable, quantitative assay to measure Crk and CrkL activity has hindered development of inhibitors. Here, we knocked down Crk, CrkL, or both using small interfering RNAs (siRNAs) in a human GBM cell line, U-118MG, to determine the respective, quantitative contributions of Crk and CrkL to cellular phenotypes. The combined use of specific and potent …