Digital Commons Network^™

The Actualization Of Maqāṣid Al-SharīʿAh In Islamic Finance: A Conceptual Framework, M.K. Hasan

Research Publications (2021 to 2025)

Purpose This paper aims to formulate a conceptual framework that will facilitate the actualization of maqāṣid al-Sharīʿah in product design and consumption within Islamic financial institutions (IFIs). Design/methodology/approach This paper relies on the classical and contemporary literature on maqāṣid al-Sharīʿah and Islamic finance and adopts a qualitative content analysis method and an inductive approach to outline the constituent elements that formulate the framework. Findings This study determines six vital constituents of maqāṣid al-Sharīʿah, namely, parameters of maqāṣid, particular objectives, appropriate means, micro provisions, level of need and legal maxims to develop a conceptual framework of actualizing maqāṣid al-Sharīʿah in Islamic …

Police Use Of Social Media Technologies, Akpomudiare Darlynton Adegor

Theses and Dissertations

This study used a qualitative research design to analyze how the Little Rock Police Department (LRPD) utilizes social media technologies to promote its community policing philosophy. I conducted a content analysis on 586 tweets by LRPD and 992 public responses posted between May 2020 and May 2021. From my analysis, I found that LRPD social media platforms support both community policing and problem-solving. LRPD uses social media for interactions, connections, and partnerships with community members. The second notable finding was that the public is responsive and receptive to LRPD’s use of social media to connect with them. However, LRPD’s level …

Simulated Presence Use For Quality Of Life Maintenance And Reduction Of Symptoms Of Distress In Persons Living With Dementia In Long-Term Care, Erin E. Bush

Dissertations

Nursing home residents with dementia often have an array of neuropsychiatric symptoms, including dementia-related agitation. It is theorized that many of these agitation symptoms occur due to unmet psychosocial needs that could be met by the presence of a caring nursing staff member, family member, or friend.

The purpose of this study was to determine whether live simulated presence improves dementia-related agitation when offered, identify barriers and facilitators to simulated presence between caregivers and residents of long-term care during the COVID-19 pandemic, and to determine if live simulated presence by a caregiver delivered one-on-one improved quality of life in long-term …

Randomized Controlled Trial Of Early Outpatient Covid-19 Treatment With High-Titer Convalescent Plasma, David J. Sullivan, Kelly A. Gebo, Shmuel Shoham, Bryan Lau, Aarthi G G Shenoy, Giselle S. Mosnaim, Thomas J. Gniadek, Yuriko Fukuta, Bela Patel, Sonya L. Heath, Adam C. Levine, Barry R. Meisenberg, Emily S. Spivak, Shweta Anjan, Moises A. Huaman, Janis E. Blair, Judith S. Currier, James H. Paxton, Jonathan M. Gerber, Joann R. Petrini, Patrick B. Broderick, William Rausch, Marie Elena Cordisco, Jean Hammel, Benjamin Greenblatt, Daniel Cruser, Kevin Oei, Matthew Abinante, Laura L. Hammitt, Catherine G. Sutcliffe, Donald N. Forthal, Martin S. Zand, Edward R. Cachay, Jay S. Raval, Seble G. Kassaye, E Colin Foster, Michael Roth, Christi E. Marshall, Anusha Yarava, Karen Lane, Nichol A. Mcbee, Amy L. Gawad, Nicky Karlen, Atika Singh, Daniel E. Ford, Douglas A. Jabs, Lawrence J. Appel, David M. Shade, Stephan Ehrhardt, Sheriza N. Baksh, Oliver Laeyendecker, Andrew Pekosz, Sabra L. Klein, Arturo Casadevall, Aaron A R Tobian, Daniel F. Hanley, Evan M. Bloch, Valerie C. Cluzet

Pathology Research and Scholarship

BACKGROUND: The efficacy of polyclonal high titer convalescent plasma to prevent serious complications of COVID-19 in outpatients with recent onset of illness is uncertain.

METHODS: This multicenter, double-blind randomized controlled trial compared the efficacy and safety of SARS-CoV-2 high titer convalescent plasma to placebo control plasma in symptomatic adults ≥18 years positive for SARS-CoV-2 regardless of risk factors for disease progression or vaccine status. Participants with symptom onset within 8 days were enrolled, then transfused within the subsequent day. The measured primary outcome was COVID-19-related hospitalization within 28 days of plasma transfusion. The enrollment period was June 3, 2020 to …

Dysregulation Of Dna Methylation And Epigenetic Clocks In Prostate Cancer Among Puerto Rican Men, Anders Berglund, Jaime Matta, Jarline Encarnación-Medina, Carmen Ortiz-Sanchéz, Julie Dutil, Raymond Linares, Joshua Marcial, Caren Abreu-Takemura, Natasha Moreno, Ryan Putney, Ratna Chakrabarti, Hui Yi Lin, Kosj Yamoah, Carlos Diaz Osterman, Liang Wang, Jasreman Dhillon, Youngchul Kim, Seung Joon Kim, Gilberto Ruiz-Deya, Jong Y. Park

School of Public Health Faculty Publications

In 2021, approximately 248,530 new prostate cancer (PCa) cases are estimated in the United States. Hispanic/Latinos (H/L) are the second largest racial/ethnic group in the US. The objective of this study was to assess DNA methylation patterns between aggressive and indolent PCa along with ancestry proportions in 49 H/L men from Puerto Rico (PR). Prostate tumors were classified as aggressive (n = 17) and indolent (n = 32) based on the Gleason score. Genomic DNA samples were extracted by macro-dissection. DNA methylation patterns were assessed using the Illumina EPIC DNA methylation platform. We used ADMIXTURE to estimate global ancestry proportions. …

Tricuspid Valve Intervention At The Time Of Pulmonary Valve Replacement In Adults With Congenital Heart Disease: A Systematic Review And Meta-Analysis, Jef Van Den Eynde, Connor P Callahan, Mauro Lo Rito, Nabil Hussein, Horacio Carvajal, Alvise Guariento, Arjang Ruhparwar, Alexander Weymann, Werner Budts, Marc Gewillig, Michel Pompeu Sá, Shelby Kutty

Open Access Publications

Background Tricuspid regurgitation (TR) is a common finding in adults with congenital heart disease referred for pulmonary valve replacement (PVR). However, indications for combined valve surgery remain controversial. This study aimed to evaluate early results of concomitant tricuspid valve intervention (TVI) at the time of PVR. Methods and Results Observational studies comparing TVI+PVR and isolated PVR were identified by a systematic search of published research. Random-effects meta-analysis was performed, comparing outcomes between the 2 groups. Six studies involving 749 patients (TVI+PVR, 278 patients; PVR, 471 patients) met the eligibility criteria. In the pooled analysis, both TVI+PVR and PVR reduced TR …

The Economic Dimensions Of Family Separation, Stephen Lee

Duke Law Journal

Migrants in the United States experience varying degrees of harm related to family separation. This article focuses on the economic dimensions of these harms by focusing on transnational remittances, a topic that has generated significant scholarly attention. Within this story, remitters are pitched as heroes and remittances are held up as a critical, market-based solution for solving global poverty. Of course, this picture is incomplete. This account ignores remittance-sending countries and provides only a narrow account of law. This Article focuses on anti-money laundering policies, an important set of U.S. laws that regulate the remittance economy. Examining remittances from this …

Regulating Homeowners' Disaster Insurance Through Federal Intervention: Lessons From The Affordable Care Act, Shannon O'Hara

Duke Law Journal

One of the most impactful effects of climate change in recent years has been the increasing frequency and severity of natural disasters, even in geographic areas not previously known as disaster-prone. These disasters have caused untold property damage. Typically, the cost of rebuilding a home is assumed at least in part by private insurance companies, but many homeowners are significantly underinsured for disaster-related losses. Additionally, in areas where natural disasters are becoming increasingly frequent, private insurers have determined that it is no longer profitable to continually issue massive payouts without charging astronomical premiums, leaving many homeowners without access to financial …

Give And Take: State Courts Should Be Able To Certify Questions Of Federal Law To Federal Courts, John Macy

Duke Law Journal

For some time, federal courts faced with unresolved questions of state law have been able to certify those questions to state courts for resolution. In the past half-century, certification practice has exploded. Nearly every state allows at least one federal court to certify questions to its state courts, and some federal courts exercise the option frequently. However, there is no analogous tool for state courts to certify questions of federal law to federal courts. This Note argues that the creation of such a tool would benefit both courts and litigants. Of course, the considerations motivating certification to state courts, such …

Commodifying Marginalization, Abbye Atkinson

Duke Law Journal

Pillars of U.S. social provision, public pension funds rely significantly on private investment to meet their chronically underfunded promises to America’s workers. Dependent on investment returns, pension funds are increasingly investing in marginalized debt, namely the array of high-interest-rate, subprime, risky debt—including small-dollar installment loans and other forms of subprime debt—that tends to concentrate in and among historically marginalized communities, often to catastrophic effect. Marginalized debt is a valuable investment because its characteristically high interest rates and myriad fees engender higher returns. In turn, higher returns ostensibly mean greater retirement security for ordinary workers who are themselves economically vulnerable in …

Is A Forensic Cohabitation Program Recovery-Oriented? A Logic Model Analysis, Shu-Ping Chen, Wen-Pin Chang, Bryan Fleet, Santoch Rai, Steve Panteluk, Alberto Choy, Deann Hunter

Occupational Therapy Faculty Publications

Background. Recovery orientation is a movement in mental health practice. Although general mental health services have taken the lead in promoting recovery, forensic psychiatric systems have lagged behind because of the need to reconcile recovery principles with the complexities of legal mandates. Advocating recovery and making systemic changes can be challenging because they require seeking a balance between the competing duties to the patient and the public. This paper used a logic model framework to demonstrate a cohabitation program that placed a woman and her newborn infant in a secure forensic rehabilitation unit, and analyzed the key assumptions of recovery …

The Health-Related Quality Of Life Of Adults With Down Syndrome, Rebecca Jermyn Graves

Dissertations

The purpose of this study was to examine the health-related quality of life (HRQOL) and factors associated with the HRQOL of adults with Down syndrome (DS) as reported by adults with DS and their caregivers. The study was designed to compare measures of HRQOL, health problems, health risks, and health-care utilization of adults with DS based on self-report with those from caregiver-report and to explore associations between HRQOL and health problems, health risks, health-care utilization, adaptive behavior, and demographic characteristics.

A Nationally Representative Survey Of Depression Symptoms Among Jordanian Adolescents: Associations With Depression Stigma, Depression Etiological Beliefs, And Likelihood To Seek Help For Depression, Latefa Ali Dardas

Dissertations

Arab adolescents are considered a particularly vulnerable population to depression. The substantial lack of mental health services and the stigma associated with mental illness on the one hand; and poverty, unemployment, and lack of reasonable hopes for a decent future in the context of corruption of regimes and perceived social injustice on the other, call for establishing committed and effective policies to tackle depression and its associated stigma among Arab adolescents at risk for or diagnosed with depression. However, there is a substantial lack of research that can inform the current profile of adolescent depression in the Arab region. We …

Questioning The Inclusivity Of Events: The Queer Perspective, Faith Ong, Clifford Lewis, Oscar Vorobjovas-Pinta

Research outputs 2014 to 2021

Event programmes are typically designed with a target audience in mind, and such design can inherently signal inclusion or exclusion of marginalised segments. This is particularly the case for lesbian, gay, bisexual, transgender, intersex and queer (LGBTIQ+) individuals, whose sexual and gender identities position them as an invisible minority on the periphery of society. Given the role of events in building community spirit, it is essential to ensure all members of a community feel able to participate in order to create a sense of belonging, fulfilling Sustainable Development Goals of inclusivity in community. Through the lens of Social Dominance Theory …

Ecological Model In School Psychology: What Are The Historical Trends In School Psychology Research?, Kerry Lynn Jones

Electronic Theses and Dissertations Archive

More than 25 years ago, Conoley and Gutkin (1995) asserted the need for more adult-focused research and related practices in school psychology. In commemorating the 25-year anniversity of Conoley and Gutkin in a special issue in School Psychology (SP), Conoley et al. (2020) revisited some of their prior assertions, such school psychology practitioners and researchers would benefit from "adopting an ecological or public health approach" (p.329). They have preserved their position on the importance of adult-focused research and related practices in order to develop and maintain health-promoting systems for students. Conoley et al. concluded that school psychology has not moved …

Recurrent High-Impact Mutations At Cognate Structural Positions In Class A G Protein-Coupled Receptors Expressed In Tumors, Eunna Huh, Jonathan Gallion, Melina A Agosto, Sara J Wright, Theodore G Wensel, Olivier Lichtarge

Faculty, Staff and Students Publications

G protein-coupled receptors (GPCRs) are the largest family of human proteins. They have a common structure and, signaling through a much smaller set of G proteins, arrestins, and effectors, activate downstream pathways that often modulate hallmark mechanisms of cancer. Because there are many more GPCRs than effectors, mutations in different receptors could perturb signaling similarly so as to favor a tumor. We hypothesized that somatic mutations in tumor samples may not be enriched within a single gene but rather that cognate mutations with similar effects on GPCR function are distributed across many receptors. To test this possibility, we systematically aggregated …

A Hybrid Machine Learning Framework For Predicting Students’ Performance In Virtual Learning Environment, Edmund Evangelista

All Works

Virtual Learning Environments (VLE), such as Moodle and Blackboard, store vast data to help identify students' performance and engagement. As a result, researchers have been focusing their efforts on assisting educational institutions in providing machine learning models to predict at-risk students and improve their performance. However, it requires an efficient approach to construct a model that can ultimately provide accurate predictions. Consequently, this study proposes a hybrid machine learning framework to predict students' performance using eight classification algorithms and three ensemble methods (Bagging, Boosting, Voting) to determine the best-performing predictive model. In addition, this study used filter-based and wrapper-based feature …

Linking Migration To Community Resilience In The Receiving Basin Of A Large-Scale Water Transfer Project, Anna Erwin, Zhao Ma, Ruxandra Popovici, Emma Patricia Salas O’Brien, Laura Zanotti, Chelsea A. Silva, Eliseo Zeballos Zeballos, Jonathan Bauchet, Nelly Ramírez Calderón, Glenn Roberto Arce Larrea

Department of Agricultural Economics Faculty Publications

Large-scale water transfer projects (LWTPs) transfer water to urban and agricultural areas. The Majes-Siguas canal, established in 1983, is an LWTP that created a thriving agricultural area through irrigating the Majes district in the Atacama Desert of Peru. Like other LWTP receiving basins, the project has attracted an influx of migrants who work on the farms. At the same time, the Majes LWTP is the district’s only source of water and has an aging infrastructure which presents significant risks. While many studies critically analyze the consequences of LWTPs in water supply basins, few evaluate the resilience of communities living in …

Sap Beetles, Nick Volesky, Zachery R. Schrumm, Kalen Taylor

All Current Publications

Sap beetles are typically considered a secondary pest of corn and overripe fruits and vegetables. They are broadly identified by their small and ovular bodies and club-shaped antennae. Adult sap beetles often feed on corn silk, pollen, and tassels. Larvae feed on kernels inside the husk. This fact sheet reviews how to identify sap beetles and their hosts and damage. It also provides ideas on how to monitor for sap beetles and outlines the options for managing them.

The Influence Of Partial Occlusion On Shape Recognition, G Schmidtmann

School of Health Professions

No abstract provided.

Winter 2021

In The Loop

2021 Emmy Nominees; Animator Tapped by Cartoon Network; IndieCade Horizons 2021; Hack4Space; Security Daemons Prevail; Role Models: DePaul Originals Game Studio students build industry-level skills that benefit themselves and others; Frames and Fortune: Eugene Bush programmed his indie video studio with patience and planning; Reality Check: Heather Snyder Quinn augments reality to question systems of unchecked power

A Next Generation Sequencing-Based Protocol For Screening Of Variants Of Concern In Autism Spectrum Disorder, Jie Huang, Jun Liu, Ruiyi Tian, Kevin Liu, Patrick Zhuang, Hannah Tayla Sherman, Christoph Budjan, Michelle Fong, Min-Seo Jeong, Xue-Jun Kong

2020-Current year OA Pubs

Autism spectrum disorder (ASD) is a neurodevelopmental disorder with strong genetic influences. There is an increasing demand for ASD genetic testing beyond the traditionally recommended microarray and syndromic autism testing; however, the current whole genome sequencing (WGS) and whole exome sequencing (WES) methods are lacking an academic standard for WGS variant annotation, reporting, and interpretation, tailored towards patients with ASD and offer very limited interpretation for clinical significance. Using WGS data from six family trios, we demonstrate the clinical feasibility and technical implementation of an evidence-based, fully transparent bioinformatics pipeline and report framework for an ASD-focused WGS genetic report. We …

Exploring End-Users’ Digital Literacy Skills In The Islamia University Of Bahawalpur, Pakistan, Muhammad Younus, Muhammad Irfan Saleem

Library Philosophy and Practice (e-journal)

This study aimed to explore end-users’ digital literacy skills in the Islamia University of Bahawalpur, Pakistan. The study employed the quantitative research method to address the research questions. The quantitative data were collected from research students (M.Phil. and PhD) studying at different departments in the university through the questionnaire. The findings of the study suggest that the respondents had a high level of knowledge and skills to use the Internet, MS Word and computers. The participants were not aware of most of electronic resources. They possessed a low level of skills to retrieve digital information, produce and create digital contents, …

Awareness And Use Of Public Library Resources: A Study In Regional Library, Tirupati, Mallimoggala Devi Archana, Kongara Surendra Babu

Library Philosophy and Practice (e-journal)

The main purpose of this study was to examine the awareness and usage of library resources by the user in Regional Library of Tirupati. To achieve the objectives of the study, a survey method was conducted using convenient sampling method. Two hundred questionnaires have been distributed to the public library users. Out of two hundred questionnaires, one hundred and seventy usable response sheets were received. This study reveals that majority of the respondents (37.65%) visit library for updating subject knowledge, 32.94% to update their employment information. It is also clear that majority of the library users (83.5%) have ICT knowledge. …

Teacher Candidates' Perspectives On Self-Care: Lessons From The Covid-19 Pandemic, Mary S. Thomas, Penny B. Howell

Kentucky Teacher Education Journal: The Journal of the Teacher Education Division of the Kentucky Council for Exceptional Children

How are teacher candidates conceptualizing self-care during the COVID 19 pandemic?

We initiated focused attention on educator self-care for teacher candidates after identifying this content as a missing yet necessary component of trauma-informed teaching (Authors, 2019). In the fall of 2020, with the COVID-19 pandemic affecting every element of candidates’ lives including our now remotely-delivered course, we reconsidered how that content needed to fit into the realities of learning to teach during a pandemic. Following these revisions, we explored the research question, how are candidates conceptualizing self-care during the COVID-19 pandemic? We describe findings and provide recommendations and resources for …

Using Cec High Leverage Practices To Prepare Teacher Candidates To Meet Individual Student Learning Needs, Michelle A. Gremp Ph.D, Ced, Julie Harp Rutland Ph.D., Maria L. Manning Ph.D., Mary Jo Krile Ph.D.

Kentucky Teacher Education Journal: The Journal of the Teacher Education Division of the Kentucky Council for Exceptional Children

Whether instruction is happening in traditional classroom settings or through a variety of virtual platforms, successful teaching requires that all teachers possess the ability to collaborate with others, evaluate student performance, establish quality learning environments, and individualize instruction. Drawing on the 2017 Council for Exceptional Children (CEC) publication, High-Leverage Practices for K-12 Special Education Teachers (McLeskey et al., 2017), the Special Education faculty at Eastern Kentucky University describe ways in which four intertwined components of collaboration, assessment, social/ emotional/behavioral practices, and instruction are incorporated into teacher preparation courses to equip candidates with skills to meet the individualized learning needs of …

The Why, The Who, The How… A Guide To Planning Effective, Collaborative, Person-Centered Transition Services For Students With Disabilities, Kristie Covington, Lorita Rowlett

Kentucky Teacher Education Journal: The Journal of the Teacher Education Division of the Kentucky Council for Exceptional Children

Providing effective transition services and plans for students with disabilities can seem like a daunting task to special education teachers and supporting agencies. Planning effective collaboration and coordination between stakeholders increases the likelihood that students with disabilities will graduate high school and participate in desired postsecondary activities, be it paid employment or postsecondary education (NTACT, 2019). Many special education teachers and supporting agencies are unsure where to start when planning and coordinating transition services; in response we created a document that can be used as a guidance and planning tool to design effective, person-centered, collaborative transition services. The planning tool …

Rotavirus Nsp1 Contributes To Intestinal Viral Replication, Pathogenesis, And Transmission, Gaopeng Hou, Qiru Zeng, Jelle Matthijnssens, Harry B Greenberg, Siyuan Ding

Open Access Publications

Rotavirus (RV)-encoded nonstructural protein 1 (NSP1), the product of gene segment 5, effectively antagonizes host interferon (IFN) signaling via multiple mechanisms. Recent studies with the newly established RV reverse genetics system indicate that NSP1 is not essential for the replication of the simian RV SA11 strain in cell culture. However, the role of NSP1 in RV infection

Sars-Cov-2 Ferritin Nanoparticle Vaccines Elicit Broad Sars Coronavirus Immunogenicity, M Gordon Joyce, Rita E Chen, James Brett Case, Michael S Diamond, Et Al

Open Access Publications

The need for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) next-generation vaccines has been highlighted by the rise of variants of concern (VoCs) and the long-term threat of emerging coronaviruses. Here, we design and characterize four categories of engineered nanoparticle immunogens that recapitulate the structural and antigenic properties of the prefusion SARS-CoV-2 spike (S), S1, and receptor-binding domain (RBD). These immunogens induce robust S binding, ACE2 inhibition, and authentic and pseudovirus neutralizing antibodies against SARS-CoV-2. A spike-ferritin nanoparticle (SpFN) vaccine elicits neutralizing titers (ID

Myeloid-Derived Suppressor Cells Mediate T Cell Dysfunction In Nonhuman Primate Tb Granulomas, Bindu Singh, Dhiraj K Singh, Shashank R Ganatra, Ruby A Escobedo, Shabaana Khader, Larry S Schlesinger, Deepak Kaushal, Smriti Mehra

Open Access Publications

Myeloid-derived suppressor cells (MDSCs) represent an innate immune cell population comprised of immature myeloid cells and myeloid progenitors with very potent immunosuppressive potential. MDSCs are reported to be abundant in the lungs of active tuberculosis (TB) patients. We sought to perform an in-depth study of MDSCs during latent TB infection (LTBI) and active TB (ATB) using the nonhuman primate (NHP) model of pulmonary TB. We found a higher proportion of granulocytic, polymorphonuclear myeloid-derived suppressor cells (PMN-MDSCs) in the lungs of ATB animals compared to those with LTBI or naive control animals. Active disease in the lung, but not LTBI, was …