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2021

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Intake Of Products Containing Anthocyanins, Flavanols, And Flavanones, And Cognitive Function: A Narrative Review, Samantha L. Gardener, Stephanie R. Rainey-Smith, Michael Weinborn, Catherine P. Bondonno, Ralph N. Martins Jan 2021

Intake Of Products Containing Anthocyanins, Flavanols, And Flavanones, And Cognitive Function: A Narrative Review, Samantha L. Gardener, Stephanie R. Rainey-Smith, Michael Weinborn, Catherine P. Bondonno, Ralph N. Martins

Research outputs 2014 to 2021

The purpose of this review is to examine human research studies published within the past 6 years which evaluate the role of anthocyanin, flavanol, and flavanone consumption in cognitive function, and to discuss potential mechanisms of action underlying any observed benefits. Evidence to date suggests the consumption of flavonoid-rich foods, such as berries and cocoa, may have the potential to limit, or even reverse, age-related declines in cognition. Over the last 6 years, the flavonoid subgroups of anthocyanins, flavanols, and flavanones have been shown to be beneficial in terms of conferring neuroprotection. The mechanisms by which flavonoids positively modulate cognitive …


“Just Like Breathing”: A Portrait Of An 85-Year-Old Veteran Teacher, Christina C. Gray, Geoffrey M. Lowe Dr, Peter F. Prout, Sarah Jefferson Jan 2021

“Just Like Breathing”: A Portrait Of An 85-Year-Old Veteran Teacher, Christina C. Gray, Geoffrey M. Lowe Dr, Peter F. Prout, Sarah Jefferson

Research outputs 2014 to 2021

Through a phenomenological lens of portraiture methodology, this article explores the career experiences of a veteran acting teacher who, at the age of 85 years, remains highly passionate and dedicated to his work with younger aspiring actors. The article reveals how for this veteran teacher, his strong teacher identity characterised by a quest for challenge and a commitment to career-long professional development are significant to maintaining relevance and passion for teaching. As many countries grapple with issues surrounding the retention of veteran teachers, understanding the ways in which he maintains his passion and commitment over succumbing to stress and burn …


Prevalence And Patterns Of Multimorbidity In Australian Baby Boomers: The Busselton Healthy Ageing Study, Michael L. Hunter, Matthew W. Knuiman, Bill A. W. Musk, Jennie Hui, Kevin Murray, John P. Beilby, David R. Hillman, Joseph Hung, Robert U. Newton, Romola S. Bucks, Leon Straker, John P. Walsh, Kun Zhu, David G. Bruce, Robert H. Eikelboom, Timothy M. E. Davis, David A. Mackey, Alan L. James Jan 2021

Prevalence And Patterns Of Multimorbidity In Australian Baby Boomers: The Busselton Healthy Ageing Study, Michael L. Hunter, Matthew W. Knuiman, Bill A. W. Musk, Jennie Hui, Kevin Murray, John P. Beilby, David R. Hillman, Joseph Hung, Robert U. Newton, Romola S. Bucks, Leon Straker, John P. Walsh, Kun Zhu, David G. Bruce, Robert H. Eikelboom, Timothy M. E. Davis, David A. Mackey, Alan L. James

Research outputs 2014 to 2021

Background and objective: Chronic medical conditions accumulate within individuals with age. However, knowledge concerning the trends, patterns and determinants of multimorbidity remains limited. This study assessed the prevalence and patterns of multimorbidity using extensive individual phenotyping in a general population of Australian middle-aged adults. Methods: Participants (n = 5029, 55% female), born between 1946 and 1964 and attending the cross-sectional phase of the Busselton Healthy Ageing Study (BHAS) between 2010 and 2015, were studied. Prevalence of 21 chronic conditions was estimated using clinical measurement, validated instrument scores and/or self-reported doctor-diagnosis. Non-random patterns of multimorbidity were explored using observed/expected (O/E) prevalence …


Usability, Acceptability, And Safety Analysis Of A Computer-Tailored Web-Based Exercise Intervention (Exerciseguide) For Individuals With Metastatic Prostate Cancer: Multi-Methods Laboratory-Based Study, Holly E. L. Evans, Cynthia C. Forbes, Daniel A. Galvão, Corneel Vandelanotte, Robert U. Newton, Gary Wittert, Suzanne Chambers, Andrew D. Vincent, Ganessan Kichenadasse, Danielle Girard, Nicholas Brook, Camille E. Short Jan 2021

Usability, Acceptability, And Safety Analysis Of A Computer-Tailored Web-Based Exercise Intervention (Exerciseguide) For Individuals With Metastatic Prostate Cancer: Multi-Methods Laboratory-Based Study, Holly E. L. Evans, Cynthia C. Forbes, Daniel A. Galvão, Corneel Vandelanotte, Robert U. Newton, Gary Wittert, Suzanne Chambers, Andrew D. Vincent, Ganessan Kichenadasse, Danielle Girard, Nicholas Brook, Camille E. Short

Research outputs 2014 to 2021

Background:

Digital health interventions such as tailored websites are emerging as valuable tools to provide individualized exercise and behavioral change information for individuals diagnosed with cancer.

Objective:

The aim of this study is to investigate and iteratively refine the acceptability and usability of a web-based exercise intervention (ExerciseGuide) for men with metastatic prostate cancer and determine how well individuals can replicate the video-based exercise prescription.

Methods:

A laboratory-based multi-methods design was used, incorporating questionnaires, think-aloud tests, interviews, and movement screening among 11 men aged 63 to 82 years with metastatic prostate cancer. Overall, 9 participants were undergoing androgen deprivation therapy, …


The Supportive Care Needs Of Regional And Remote Cancer Caregivers, Anna Stiller, Belinda C. Goodwin, Fiona Crawford-Williams, Sonja March, Michael Ireland, Joanne F. Aitken, Jeff Dunn, Suzanne K. Chambers Jan 2021

The Supportive Care Needs Of Regional And Remote Cancer Caregivers, Anna Stiller, Belinda C. Goodwin, Fiona Crawford-Williams, Sonja March, Michael Ireland, Joanne F. Aitken, Jeff Dunn, Suzanne K. Chambers

Research outputs 2014 to 2021

Objective: As cancer survival rates continue to increase, so will the demand for care from family and friends, particularly in more isolated settings. This study aims to examine the needs of cancer caregivers in regional and remote Australia. Methods: A total of 239 informal (i.e., non-professional) cancer caregivers (e.g., family/friends) from regional and remote Queensland, Australia, completed the Comprehensive Needs Assessment Tool for Cancer Caregivers (CNAT-C). The frequencies of individuals reporting specific needs were calculated. Logistic regression analyses assessed the association between unmet needs and demographic characteristics and cancer type. Results: The most frequently endorsed needs were lodging near hospital …


The Role Of Acceptance And Commitment Therapy In Cardiovascular And Diabetes Healthcare: A Scoping Review, Amineh Rashidi, Lisa Whitehead, Lisa Newson, Felicity Astin, Paramjit Gill, Deirdre A. Lane, Gregory Y. H. Lip, Lis Neubeck, Chantal F. Ski, David R. Thompson, Helen Walthall, Ian D. Jones Jan 2021

The Role Of Acceptance And Commitment Therapy In Cardiovascular And Diabetes Healthcare: A Scoping Review, Amineh Rashidi, Lisa Whitehead, Lisa Newson, Felicity Astin, Paramjit Gill, Deirdre A. Lane, Gregory Y. H. Lip, Lis Neubeck, Chantal F. Ski, David R. Thompson, Helen Walthall, Ian D. Jones

Research outputs 2014 to 2021

Acceptance and commitment therapy (ACT) is an adapted form of cognitive behavioural therapy. ACT focuses on how thinking affects behaviour and promotes psychological flexibility. The prevalence of psychological distress among people living with cardiovascular disease (CVD) and/or type 2 diabetes mellitus (T2DM) is high, and ACT may offer an alternative treatment approach. This scoping review explored the use of ACT as an intervention to support adults living with CVD and/or T2DM. A systematic search of the literature resulted in the inclusion of 15 studies. Studies were reviewed using the Joanna Briggs Institute approach to conducting scoping reviews. Most studies (n …


Analysis Of The Use And Perception Of Shared Mobility: A Case Study In Western Australia, Craig Standing, Ferry Jie, Thi Le, Susan Standing, Sharon Biermann Jan 2021

Analysis Of The Use And Perception Of Shared Mobility: A Case Study In Western Australia, Craig Standing, Ferry Jie, Thi Le, Susan Standing, Sharon Biermann

Research outputs 2014 to 2021

The sharing economy has acquired a lot of media attention in recent years, and it has had a significant impact on the transport sector. This paper investigates the existing impact and potential of various forms of shared mobility, concentrating on the case study of Wanneroo, Western Australia. We adopted bibliometric analysis and visualization tools based on nearly 700 papers collected from the Scopus database to identify research clusters on shared mobility. Based on the clusters identified, we undertook a further content analysis to clarify the factors affecting the potential of different shared mobility modes. A specially designed questionnaire was applied …


Development And Validation Of The Holistic Cognition Scale, Andrei A. Lux, Steven L. Grover, Stephen T. Teo Jan 2021

Development And Validation Of The Holistic Cognition Scale, Andrei A. Lux, Steven L. Grover, Stephen T. Teo

Research outputs 2014 to 2021

This paper introduces a new scale to measure cognitive cultural differences, drawing on the theory of analytic versus holistic thought. Examining culture from a cognitive perspective is a challenge to traditional values-based approaches. Existing measures based on this framework are methodologically problematic and warrant renewal. This paper presents development and validation studies for a new instrument that measures analytic versus holistic cognitive tendencies at the individual level. The scale assesses four previously established dimensions: attention, causality, contradiction, and change. The present work follows well-established scale development protocols and the results show that the 16-item Holistic Cognition Scale (HCS) is a …


Video Analysis And Verification Of Direct Head Impacts Recorded By Wearable Sensors In Junior Rugby League Players, Lauchlan Carey, Douglas P. Terry, Andrew S. Mcintosh, Peter Stanwell, Grant L. Iverson, Andrew J. Gardner Jan 2021

Video Analysis And Verification Of Direct Head Impacts Recorded By Wearable Sensors In Junior Rugby League Players, Lauchlan Carey, Douglas P. Terry, Andrew S. Mcintosh, Peter Stanwell, Grant L. Iverson, Andrew J. Gardner

Research outputs 2014 to 2021

Background: Rugby league is a high-intensity collision sport that carries a risk of concussion. Youth athletes are considered to be more vulnerable and take longer to recover from concussion than adult athletes. Purpose: To review head impact events in elite-level junior representative rugby league and to verify and describe characteristics of X-patchTM-recorded impacts via video analysis. Study Design: Observational case series. Methods: The X-patchTM was used on twenty-one adolescent players (thirteen forwards and eight backs) during a 2017 junior representative rugby league competition. Game-day footage, recorded by a trained videographer from a single camera, was synchronised with X-patchTM-recorded timestamped events. …


Chinese International Students In The United States: The Interplay Of Students’ Acculturative Stress, Academic Standing, And Quality Of Life, Zhaohui Su, Dean Mcdonnell, Feng Shi, Bin Liang, Xiaoshan Li, Jun Wen, Yuyang Cai, Yu-Tao Xiang, Ling Yang Jan 2021

Chinese International Students In The United States: The Interplay Of Students’ Acculturative Stress, Academic Standing, And Quality Of Life, Zhaohui Su, Dean Mcdonnell, Feng Shi, Bin Liang, Xiaoshan Li, Jun Wen, Yuyang Cai, Yu-Tao Xiang, Ling Yang

Research outputs 2014 to 2021

Background: Acculturation could cause grave health consequences in international students. However, there is a shortage of research into how acculturative stress might affect international students’ quality of life in light of their academic standing and experience. The lack of research is particularly pronounced among Chinese international students, representing the largest body of international students studying in the United States (U.S.). Thus, to bridge the research gap, this study aims to examine the interplay between international students’ acculturative stress, academic standing, and quality of life among a nationally representative sample of Chinese international students studying in the United States. Methods: An …


Comparison Of Experiences In Two Birth Cohorts Comprising Young Families With Children Under Four Years During The Initial Covid-19 Lockdown In Australia And The Uk: A Qualitative Study, Lisa Y. Gibson, Bridget Lockyer, Josie Dickerson, Charlotte Endacott, Sally Bridges, Rosemary R. C. Mceachan, Kate E. Pickett, Sarah Whalan, Natasha L. Bear, Desiree T. Silva, Susan L. Prescott, Jacqueline A. Davis Jan 2021

Comparison Of Experiences In Two Birth Cohorts Comprising Young Families With Children Under Four Years During The Initial Covid-19 Lockdown In Australia And The Uk: A Qualitative Study, Lisa Y. Gibson, Bridget Lockyer, Josie Dickerson, Charlotte Endacott, Sally Bridges, Rosemary R. C. Mceachan, Kate E. Pickett, Sarah Whalan, Natasha L. Bear, Desiree T. Silva, Susan L. Prescott, Jacqueline A. Davis

Research outputs 2014 to 2021

This study aims to understand the experience and impact of the initial COVID-19 lock-down in young families with children aged below 4 years. Free text questions were administered to participants in the ORIGINS (Australia) and Born in Bradford (UK) cohort studies to collect qualitative information on worries, concerns and enjoyable experiences during the pandemic. A total of 903 (400 for ORIGINS and 503 for BiB) participants completed the two surveys during April 2020. Despite varying in geography, levels of socio-economic disadvantage and their situational context during the pandemic, respondents from both cohorts reported similar worries and challenges during the lockdown …


A Novel Boot Camp Program To Help Guide Personalized Exercise In People With Parkinson Disease, Josefa Domingos, John Dean, Travis M. Cruickshank, Katarzyna Śmiłowska, Júlio Belo Fernandes, Catarina Godinho Jan 2021

A Novel Boot Camp Program To Help Guide Personalized Exercise In People With Parkinson Disease, Josefa Domingos, John Dean, Travis M. Cruickshank, Katarzyna Śmiłowska, Júlio Belo Fernandes, Catarina Godinho

Research outputs 2014 to 2021

Given the variety of exercise programs available for people with Parkinson’s disease (PD), such individuals may struggle to make decisions about what exercise to perform. The objective of this study was to assess the usefulness, satisfaction, and preferences regarding participation in a PD-personalized educational and exercise boot camp program. Attendees participated in a four-day program consisting of exercise sessions, workshops, and social activities. We collected demographic and clinical information. We assessed satisfaction and preferences immediately after. At one-month follow-up, participants assessed usefulness and changes in exercise habits. Eight individuals diagnosed with PD, with a mean age of 59.5 ± 6.8 …


Biometrics For Internet‐Of‐Things Security: A Review, Wencheng Yang, Song Wang, Nor Masri Sahri, Nickson M. Karie, Mohiuddin Ahmed, Craig Valli Jan 2021

Biometrics For Internet‐Of‐Things Security: A Review, Wencheng Yang, Song Wang, Nor Masri Sahri, Nickson M. Karie, Mohiuddin Ahmed, Craig Valli

Research outputs 2014 to 2021

The large number of Internet‐of‐Things (IoT) devices that need interaction between smart devices and consumers makes security critical to an IoT environment. Biometrics offers an interesting window of opportunity to improve the usability and security of IoT and can play a significant role in securing a wide range of emerging IoT devices to address security challenges. The purpose of this review is to provide a comprehensive survey on the current biometrics research in IoT security, especially focusing on two important aspects, authentication and encryption. Regarding authentication, contemporary biometric‐based authentication systems for IoT are discussed and classified based on different biometric …


Potential Of Sorghum Polyphenols To Prevent And Treat Alzheimer's Disease: A Review Article, Nasim Rezaee, Warnakulasuriya Mary Ann Dipika Fernando, Eugene Hone, Hamid R. Sohrabi, Stuart K. Johnson, Stuart Gunzburg, Ralph Martins Jan 2021

Potential Of Sorghum Polyphenols To Prevent And Treat Alzheimer's Disease: A Review Article, Nasim Rezaee, Warnakulasuriya Mary Ann Dipika Fernando, Eugene Hone, Hamid R. Sohrabi, Stuart K. Johnson, Stuart Gunzburg, Ralph Martins

Research outputs 2014 to 2021

Alzheimer’s disease (AD) is characterized by the excessive deposition of extracellular amyloid-beta peptide (Aβ) and the build-up of intracellular neurofibrillary tangles containing hyperphosphorylated tau proteins. This leads to neuronal damage, cell death and consequently results in memory and learning impairments leading to dementia. Although the exact cause of AD is not yet clear, numerous studies indicate that oxidative stress, inflammation, and mitochondrial dysfunction significantly contribute to its onset and progression. There is no effective therapeutic approach to stop the progression of AD and its associated symptoms. Thus, early intervention, preferably, pre-clinically when the brain is not significantly affected, is a …


Kinematic And Neuromuscular Measures Of Intensity During Drop Jumps In Female Volleyball Players, Maximiliano Torres-Banduc, Rodrigo Ramirez-Campillo, David Cristobal Andrade, Julio Calleja-González, Pantelis Theo Nikolaidis, John J. Mcmahon, Paul Comfort Jan 2021

Kinematic And Neuromuscular Measures Of Intensity During Drop Jumps In Female Volleyball Players, Maximiliano Torres-Banduc, Rodrigo Ramirez-Campillo, David Cristobal Andrade, Julio Calleja-González, Pantelis Theo Nikolaidis, John J. Mcmahon, Paul Comfort

Research outputs 2014 to 2021

The aim of this study was to assess drop jump (DJ) performance variables (jump height, contact time, and reactive strength index) concomitant to surface electromyography (sEMG) of lower limb muscles during DJs from different drop heights (intensities). The eccentric and concentric phase sEMG from the gastrocnemius medialis, biceps femoris, and vastus medialis muscles were assessed during all tests, with sEMG activity normalized to maximal voluntary isometric contraction (MVIC). In a cross-sectional, study, 10 amateur female volleyball players (age 22.1 ± 1.8 years; body mass 72.9 ± 15.2 kg; height 1.70 ± 0.08 m) completed DJs from six heights [15-90 cm …


The Development Of Aboriginal Brain Injury Coordinator Positions: A Culturally Secure Rehabilitation Service Initiative As Part Of A Clinical Trial, Elizabeth Armstrong, Kathy Mccoy, Rebecca Clinch, Maureen Merritt, Renee Speedy, Meaghan Mcallister, Kym Heine, Natalie Ciccone, Melanie Robinson, Julie Coffin Jan 2021

The Development Of Aboriginal Brain Injury Coordinator Positions: A Culturally Secure Rehabilitation Service Initiative As Part Of A Clinical Trial, Elizabeth Armstrong, Kathy Mccoy, Rebecca Clinch, Maureen Merritt, Renee Speedy, Meaghan Mcallister, Kym Heine, Natalie Ciccone, Melanie Robinson, Julie Coffin

Research outputs 2014 to 2021

Brain injury, resulting from stroke and traumatic brain injury, is a common occurrence in Australia, with Aboriginal people affected at a significant rate and impact felt by individuals, families and communities. Access to brain injury rehabilitation services for Aboriginal people is reported to be often limited, with very little support outside the hospital environment. Our research involving Aboriginal brain injury survivors and their families to date has revealed that people often manage ‘on their own’ following such events. Following recommendations from survivors and their families, the Healing Right Way clinical trial, currently underway in Western Australia, has created the role …


‘Believe In Me, And I Will Too’: A Study Of How Teachers’ Expectations Instilled Confidence In Grade 10 Students, Olivia Johnston, Helen Wildy, Jennifer Shand Jan 2021

‘Believe In Me, And I Will Too’: A Study Of How Teachers’ Expectations Instilled Confidence In Grade 10 Students, Olivia Johnston, Helen Wildy, Jennifer Shand

Research outputs 2014 to 2021

Teacher expectation research has continued to establish an association between what teachers expect of their students and what students accomplish academically. These expectations affect students when they are communicated by teachers through differential treatment in the class, but no qualitative research has sought adolescent students’ points of view about how they experience teacher expectation effects. This paper presents new research findings that explain how Grade 10 students experienced their teachers’ expectations in ways that they reflected impacted their academic outcomes. Classic grounded theory methods were used to develop this new knowledge, which has implications for how teachers are educated for, …


Development Support Of Early Career Researchers In The Netherlands: Lessons For Australia, Craig P. Speelman Jan 2021

Development Support Of Early Career Researchers In The Netherlands: Lessons For Australia, Craig P. Speelman

Research outputs 2014 to 2021

Australian universities are faced with the imminent retirement of a large proportion of their researchers. One way to avoid a decrement in research performance is to consider greater support for early career researchers (ECRs). To investigate how another university system that is ranked high in research performance supports its ECRs several universities in the Netherlands were visited. Seventeen senior academic staff in these universities were interviewed to examine their perceptions of the support that is provided for the development of ECRs, and the nature of the research environment in which they are employed. Interviews were recorded, transcribed, and coded using …


Optimal Sizing Of Energy Storage System To Reduce Impacts Of Transportation Electrification On Power Distribution Transformers Integrated With Photovoltaic, Pravakar Pradhan, Iftekhar Ahmad, Daryoush Habibi, Asma Aziz, Bassam Al-Hanahi, Mohammad A S Masoum Jan 2021

Optimal Sizing Of Energy Storage System To Reduce Impacts Of Transportation Electrification On Power Distribution Transformers Integrated With Photovoltaic, Pravakar Pradhan, Iftekhar Ahmad, Daryoush Habibi, Asma Aziz, Bassam Al-Hanahi, Mohammad A S Masoum

Research outputs 2014 to 2021

Transportation systems are one of the leading sectors that contribute to greenhouse gas emissions that lead to enhance global warming. The electrification of vehicles is a promising solution to this widespread problem; however, integrating electric vehicles (EVs) into existing grid systems on a large scale creates several problems, both for consumers and for utilities. Accelerated aging of expensive grid assets, such as power transformers, is one of the primary issues that these utilities are facing. This problem can be addressed with battery energy storage systems (BESS), which acts as buffer between demand and supply. Accordingly, this paper proposes a novel …


Designing Call To Action: Users' Perception Of Different Charateristics, Thomas Mejtoft, Jonathan Hedlund, Helen Cripps, Ulrik Söderström, Ole Norberg Jan 2021

Designing Call To Action: Users' Perception Of Different Charateristics, Thomas Mejtoft, Jonathan Hedlund, Helen Cripps, Ulrik Söderström, Ole Norberg

Research outputs 2014 to 2021

This paper aims to provide guidance when designing a call to action in a digital system with the purpose to create an intended feeling and user engagement. The paper is based on a test of four different simple call to action constructions. The users clearly prefer constructions that have a high explainability and feels intuitive. Hence, the design should have a high level of transparency and show the user straight away what it demands from the user and what the result of the action is. Furthermore, the design should have a high usability to make it clear how to use …


The Power Of The Individual Voice: Interrogating Continuity At A Time When The Open Communication Of Research Is Disrupted By Unruly Speakers And Publics, Lelia Green, Viet Tho Le Jan 2021

The Power Of The Individual Voice: Interrogating Continuity At A Time When The Open Communication Of Research Is Disrupted By Unruly Speakers And Publics, Lelia Green, Viet Tho Le

Research outputs 2014 to 2021

Hyperconnected societies offer new opportunities for the role of the individual voice. A deregulated world of information poses a paradox, however, in which fake news might conceivably underpin the political agenda more than informed research. The sheer amount of information available forces publics and audience members to seek shortcuts to knowledge through access to preferred academic, public intellectual or ‘thought leader’ perspectives. Drawing upon theories of deliberative democracy and open communication, this paper critiques the roles of academic, public intellectual and thought leader to move beyond discussion of the value of individual voices in the sharing of knowledge. It suggests …


Meta-Analysis Of Genome-Wide Dna Methylation Identifies Shared Associations Across Neurodegenerative Disorders, Marta F. Nabais, Simon M. Laws, Tian Lin, Costanza L. Vallerga, Nicola J. Armstrong, Ian P. Blair, John B. Kwok, Karen A. Mather, George D. Mellick, Perminder S. Sachdev, Leanne Wallace, Anjali K. Henders, Ramona A. J. Zwamborn, Paul J. Hop, Katie Lunnon, Ehsan Pishva, Janou A. Y. Roubroeks, Hilkka Soininen, Magda Tsolaki, Patrizia Mecocci, Simon Lovestone, Iwona Kłoszewska, Bruno Vellas, Sarah Furlong, Fleur C. Garton, Robert D. Henderson, Susan Mathers, Pamela A. Mccombe, Merrilee Needham, Shyuan T. Ngo, Garth Nicholson, Roger Pamphlett, Dominic B. Rowe, Frederik J. Steyn, Kelly L. Williams, Tim J. Anderson, Steven R. Bentley, John Dalrymple-Alford, Javed Fowder, Jacob Gratten, Glenda Halliday, Ian B. Hickie, Martin Kennedy, Simon J. G. Lewis, Grant W. Montgomery, John Pearson, Toni L. Pitcher, Peter Silburn, Futao Zhang, Peter M. Visscher, Jian Yang, Anna J. Stevenson, Robert F. Hillary, Riccardo E. Marioni, Sarah E. Harris, Ian J. Deary, Ashley R. Jones, Aleksey Shatunov, Alfredo Iacoangeli, Wouter Van Rheenen, Leonard H. Van Den Berg, Pamela J. Shaw, Cristopher E. Shaw, Karen E. Morrison, Ammar Al-Chalabi, Jan H. Veldink, Eilis Hannon, Jonathan Mill, Naomi R. Wray, Allan F. Mcrae, The Alzheimer's Disease Neuroimaging Initiative, The Australian Imaging Biomarkers And Lifestyle Study Jan 2021

Meta-Analysis Of Genome-Wide Dna Methylation Identifies Shared Associations Across Neurodegenerative Disorders, Marta F. Nabais, Simon M. Laws, Tian Lin, Costanza L. Vallerga, Nicola J. Armstrong, Ian P. Blair, John B. Kwok, Karen A. Mather, George D. Mellick, Perminder S. Sachdev, Leanne Wallace, Anjali K. Henders, Ramona A. J. Zwamborn, Paul J. Hop, Katie Lunnon, Ehsan Pishva, Janou A. Y. Roubroeks, Hilkka Soininen, Magda Tsolaki, Patrizia Mecocci, Simon Lovestone, Iwona Kłoszewska, Bruno Vellas, Sarah Furlong, Fleur C. Garton, Robert D. Henderson, Susan Mathers, Pamela A. Mccombe, Merrilee Needham, Shyuan T. Ngo, Garth Nicholson, Roger Pamphlett, Dominic B. Rowe, Frederik J. Steyn, Kelly L. Williams, Tim J. Anderson, Steven R. Bentley, John Dalrymple-Alford, Javed Fowder, Jacob Gratten, Glenda Halliday, Ian B. Hickie, Martin Kennedy, Simon J. G. Lewis, Grant W. Montgomery, John Pearson, Toni L. Pitcher, Peter Silburn, Futao Zhang, Peter M. Visscher, Jian Yang, Anna J. Stevenson, Robert F. Hillary, Riccardo E. Marioni, Sarah E. Harris, Ian J. Deary, Ashley R. Jones, Aleksey Shatunov, Alfredo Iacoangeli, Wouter Van Rheenen, Leonard H. Van Den Berg, Pamela J. Shaw, Cristopher E. Shaw, Karen E. Morrison, Ammar Al-Chalabi, Jan H. Veldink, Eilis Hannon, Jonathan Mill, Naomi R. Wray, Allan F. Mcrae, The Alzheimer's Disease Neuroimaging Initiative, The Australian Imaging Biomarkers And Lifestyle Study

Research outputs 2014 to 2021

Background: People with neurodegenerative disorders show diverse clinical syndromes, genetic heterogeneity, and distinct brain pathological changes, but studies report overlap between these features. DNA methylation (DNAm) provides a way to explore this overlap and heterogeneity as it is determined by the combined effects of genetic variation and the environment. In this study, we aim to identify shared blood DNAm differences between controls and people with Alzheimer’s disease, amyotrophic lateral sclerosis, and Parkinson’s disease. Results: We use a mixed-linear model method (MOMENT) that accounts for the effect of (un)known confounders, to test for the association of each DNAm site with each …


Hybrid Mamdani Fuzzy Rules And Convolutional Neural Networks For Analysis And Identification Of Animal Images, Hind R. Mohammed, Zahir M. Hussain Jan 2021

Hybrid Mamdani Fuzzy Rules And Convolutional Neural Networks For Analysis And Identification Of Animal Images, Hind R. Mohammed, Zahir M. Hussain

Research outputs 2014 to 2021

Accurate, fast, and automatic detection and classification of animal images is challenging, but it is much needed for many real-life applications. This paper presents a hybrid model of Mamdani Type-2 fuzzy rules and convolutional neural networks (CNNs) applied to identify and distinguish various animals using different datasets consisting of about 27,307 images. The proposed system utilizes fuzzy rules to detect the image and then apply the CNN model for the object’s predicate category. The CNN model was trained and tested based on more than 21,846 pictures of animals. The experiments’ results of the proposed method offered high speed and efficiency, …


Prevalence Of Distress, Its Associated Factors And Referral To Support Services In People With Cancer, Deborah Kirk, Istvan (Ishti) Kabdebo, Lisa Whitehead Jan 2021

Prevalence Of Distress, Its Associated Factors And Referral To Support Services In People With Cancer, Deborah Kirk, Istvan (Ishti) Kabdebo, Lisa Whitehead

Research outputs 2014 to 2021

Aims and objectives:

To (i) characterise prevalence of distress amongst people diagnosed with cancer, (ii) determine factors associated with increasing distress, (iii) describe reported problems for those with clinically significant distress and (iv) investigate the factors associated with referral to support services.

Background:

International studies report a high prevalence of clinically significant distress in people with cancer. Australian studies are notably lacking. Additionally, clinicians still do not fully understand the factors associated with cancer-related distress.

Design:

Period prevalence study.

Methods:

Distress screening data were analysed for 1,071 people accessing the Cancer Council Western Australia information and support line between 01/01/2016–31/12/2018. …


Educational Outcomes Of Adolescents Participating In Specialist Sport Programs In Low Ses Areas Of Western Australia: A Mixed Methods Study, Eibhlish O'Hara, Craig Harms, Fadi Ma'ayah, Craig Speelman Jan 2021

Educational Outcomes Of Adolescents Participating In Specialist Sport Programs In Low Ses Areas Of Western Australia: A Mixed Methods Study, Eibhlish O'Hara, Craig Harms, Fadi Ma'ayah, Craig Speelman

Research outputs 2014 to 2021

Specialist Sport Programs (SSPs) are an underexamined activity that combines the best features of two different contexts for adolescent development: a sporting program and a secondary school. A mixed-methods study was conducted to determine the influence of participation in SSPs on the educational outcomes of lower secondary students in Western Australia. The results demonstrated a significant improvement in specialist students' mean grade for Mathematics over the course of a year, while their mean grade for all other subjects, and their level of engagement with school, remained stable over the same period of time. Semi-structured interviews were also conducted with key …


Exercise Medicine In The Management Of Pancreatic Cancer: A Systematic Review, Hao Luo, Daniel A. Galvão, Robert U. Newton, Pedro Lopez Da Cruz, Colin Tang, Ciaran M. Fairman, Nigel Spry, Dennis R. Taaffe Jan 2021

Exercise Medicine In The Management Of Pancreatic Cancer: A Systematic Review, Hao Luo, Daniel A. Galvão, Robert U. Newton, Pedro Lopez Da Cruz, Colin Tang, Ciaran M. Fairman, Nigel Spry, Dennis R. Taaffe

Research outputs 2014 to 2021

The aim of this study was to examine the health-related effects of exercise in patients with pancreatic cancer (PanCa) through a systematic review of current evidence. Studies were obtained through searching PubMed, Web of Science, PsycINFO, Embase, CINAHL Plus, and Cochrane Library databases with additional hand searches. All intervention-based studies were included if it involved (1) adult patients with PanCa, (2) exercise training, and (3) findings in quality of life, cancer-related fatigue, psychological distress, and physical function. The review protocol was registered in PROSPERO: CRD42020154684. Seven trials described in 9 publications were included consisting of 201 patients with early-stage and …


A Narrative Review Of The Pharmacological, Cultural And Psychological Literature On Ibogaine, Martie S. Underwood, Stephen J. Bright, B. Les Lancaster Jan 2021

A Narrative Review Of The Pharmacological, Cultural And Psychological Literature On Ibogaine, Martie S. Underwood, Stephen J. Bright, B. Les Lancaster

Research outputs 2014 to 2021

Ibogaine is a psychoactive alkaloid contained in the West African plant Tabernanthe iboga. Although preliminary, evidence suggests that ibogaine could be effective in the treatment of certain substance use disorders, specifically opioid use disorder. This narrative review concentrated on the pharmacological, cultural and psychological aspects of ibogaine that contribute to its reputed effectiveness with a specific focus on the ibogaine state of consciousness. Although the exact pharmacological mechanisms for ibogaine are still speculative, the literature highlighted its role as an NMDA antagonist in the effective treatment of substance use disorders. The cultural aspects associated with the use of ibogaine pose …


Longitudinal Trajectories In Cortical Thickness And Volume Atrophy: Superior Cognitive Performance Does Not Protect Against Brain Atrophy In Older Adults, Samantha Gardener, Michael Weinborn, Hamid R. Sohrabi, James Doecke, Pierrick Bourgeat, Stephanie R. Rainey-Smith, Kai-Kai Shen, Jurgen Fripp, Kevin Taddei, Paul Maruff, Olivier Salvado, Greg Savage, David Ames, Colin L. Masters, Christopher C. Rowe, Ralph Martins, Aibl Research Group Jan 2021

Longitudinal Trajectories In Cortical Thickness And Volume Atrophy: Superior Cognitive Performance Does Not Protect Against Brain Atrophy In Older Adults, Samantha Gardener, Michael Weinborn, Hamid R. Sohrabi, James Doecke, Pierrick Bourgeat, Stephanie R. Rainey-Smith, Kai-Kai Shen, Jurgen Fripp, Kevin Taddei, Paul Maruff, Olivier Salvado, Greg Savage, David Ames, Colin L. Masters, Christopher C. Rowe, Ralph Martins, Aibl Research Group

Research outputs 2014 to 2021

Background:

Previous research has identified a small subgroup of older adults that maintain a high level of cognitive functioning well into advanced age. Investigation of those with superior cognitive performance (SCP) for their age is important, as age-related decline has previously been thought to be inevitable.

Objective:

Preservation of cortical thickness and volume was evaluated in 76 older adults with SCP and 100 typical older adults (TOAs) assessed up to five times over six years.

Methods:

Regions of interest (ROIs) found to have been associated with super-aging status (a construct similar to SCP status) in previous literature were investigated, followed …


Communication Surrounding Initiation And Withdrawal Of Non-Invasive Ventilation In Adults With Motor Neuron(E) Disease: Clinicians’ And Family Members’ Perspectives, Charlotte Chapman, Sara Bayes, Moira Sim Jan 2021

Communication Surrounding Initiation And Withdrawal Of Non-Invasive Ventilation In Adults With Motor Neuron(E) Disease: Clinicians’ And Family Members’ Perspectives, Charlotte Chapman, Sara Bayes, Moira Sim

Research outputs 2014 to 2021

Introduction: International guidelines recommend that health care clinicians communicate with people with MND and their family members about non-invasive ventilation (NIV) and percutaneous gastrostomy tube (PEG) prior to or at the onset of respiratory symptoms. This study sought to discover the degree to which these recommendations are followed in practice.

Methods: Interpretive Description methodology was employed. Nineteen clinicians experienced in caring for people with MND, six relatives of recently deceased people with MND and one person with MND participated in semi-structured in-depth interviews. Clinicians’ accounts of NIV and PEG related communications were compared to family member participants’ recollections of their …


Contact, Moral Foundations Or Knowledge? What Predicts Attitudes Towards Women Who Undergo Ivf, Alicja Malina, Marta Roczniewska, Julie Ann Pooley Jan 2021

Contact, Moral Foundations Or Knowledge? What Predicts Attitudes Towards Women Who Undergo Ivf, Alicja Malina, Marta Roczniewska, Julie Ann Pooley

Research outputs 2014 to 2021

Background: The willingness to try in vitro fertilization (IVF) as an infertility treatment, as well as its psychosocial consequences for couples, may be influenced by how they perceive the attitudes of general public towards this procedure. The focus of the current study was to identify predictors of attitudes towards mothers who underwent IVF to conceive a child. Three predictors were derived from attitude components: contact with someone who had undergone IVF (behavior), moral foundations (emotions), and the level of knowledge (cognition) about IVF. Method: In total, 817 participants (118 male and 692 female, 7 unreported) from Poland took part in …