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2021

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Healing Right Way: Study Protocol For A Stepped Wedge Cluster Randomised Controlled Trial To Enhance Rehabilitation Services And Improve Quality Of Life In Aboriginal Australians After Brain Injury, Elizabeth Armstrong, Juli Coffin, Deborah J. Hersh, Judith M. Katzenellenbogen, Sandra Thompson, Leon Flicker, Meaghan Mcallister, Dominique A. Cadilhac, Tapan Rai, Erin Godecke, Colleen Hayward, Graeme J. Hankey, Neil M. Drew, Ivan Lin, Deborah Woods, Natalie Ciccone Jan 2021

Healing Right Way: Study Protocol For A Stepped Wedge Cluster Randomised Controlled Trial To Enhance Rehabilitation Services And Improve Quality Of Life In Aboriginal Australians After Brain Injury, Elizabeth Armstrong, Juli Coffin, Deborah J. Hersh, Judith M. Katzenellenbogen, Sandra Thompson, Leon Flicker, Meaghan Mcallister, Dominique A. Cadilhac, Tapan Rai, Erin Godecke, Colleen Hayward, Graeme J. Hankey, Neil M. Drew, Ivan Lin, Deborah Woods, Natalie Ciccone

Research outputs 2014 to 2021

Introduction: Despite higher incidence of brain injury among Aboriginal compared with non-Aboriginal Australians, suboptimal engagement exists between rehabilitation services and Aboriginal brain injury survivors. Aboriginal patients often feel culturally insecure in hospital and navigation of services post discharge is complex. Health professionals report feeling ill-equipped working with Aboriginal patients. This study will test the impact of a research-informed culturally secure intervention model for Aboriginal people with brain injury.

Methods and Analysis: Design: Stepped wedge cluster randomised control trial design; intervention sequentially introduced at four pairs of healthcare sites across Western Australia at 26-week intervals.

Recruitment: Aboriginal participants aged ≥18 years …


An Integrated Multicomponent Care Model For Men Affected By Prostate Cancer: A Feasibility Study Of Truenth Australia, Patsy Yates, Rob Carter, Robyn Cockerell, Donna Cowan, Cyril Dixon, Anne Magnus, Robert U. Newton, Nicolas H. Hart, Daniel A. Galvão, Brenton Baguley, Nicholas Denniston, Tina Skinner, Jeremy Couper, Jon Emery, Mark Frydenberg, Wei-Hong Liu Jan 2021

An Integrated Multicomponent Care Model For Men Affected By Prostate Cancer: A Feasibility Study Of Truenth Australia, Patsy Yates, Rob Carter, Robyn Cockerell, Donna Cowan, Cyril Dixon, Anne Magnus, Robert U. Newton, Nicolas H. Hart, Daniel A. Galvão, Brenton Baguley, Nicholas Denniston, Tina Skinner, Jeremy Couper, Jon Emery, Mark Frydenberg, Wei-Hong Liu

Research outputs 2014 to 2021

Objective: To evaluate the feasibility of implementing an integrated multicomponent survivorship care model for men affected by prostate cancer. Methods: Using a single arm prospective cohort study design, men with prostate cancer were recruited from two regional public hospitals in Australia for a 6-months program that provided information and decision support, exercise and nutrition management, specialised clinical support, and practical support through localised and central care coordination. Carers of the men were also invited to the program. Data were collected from multiple sources to evaluate: (1) recruitment capability and participant characteristics; (2) appropriateness and feasibility of delivering the specific intervention …


Changes In Plasma C1q, Apelin And Adropin Concentrations In Older Adults After Descending And Ascending Stair Walking Intervention, Trevor C. Chen, Tsang-Hai Huang, Wei-Chin Tseng, Kuo-Wei Tseng, Chung-Chan Hsieh, Mei-Yen Chen, Tai-Ying Chou, Yuh-Chuan Huang, Hsin-Lian Chen, Kazunori Nosaka Jan 2021

Changes In Plasma C1q, Apelin And Adropin Concentrations In Older Adults After Descending And Ascending Stair Walking Intervention, Trevor C. Chen, Tsang-Hai Huang, Wei-Chin Tseng, Kuo-Wei Tseng, Chung-Chan Hsieh, Mei-Yen Chen, Tai-Ying Chou, Yuh-Chuan Huang, Hsin-Lian Chen, Kazunori Nosaka

Research outputs 2014 to 2021

This study compared changes in plasma complement component 1q (C1q), apelin and adropin concentrations in older obese women after descending (DSW) and ascending stair walking (ASW) training (n = 15/group) performed twice a week for 12 weeks, with gradual increases in exercise time from 5 to 60 min. Fasting blood samples were collected 3 days before the first and 4 days after the last training session. The improvements in the maximal voluntary isometric contraction (MVIC) strength of the knee extensors, functional physical fitness [e.g., 30-s chair stand (CS) performance], resting systolic blood pressure (SBP), insulin sensitivity [e.g., oral glucose tolerance …


A Review Of Security Standards And Frameworks For Iot-Based Smart Environments, Nickson M. Karie, Nor Masri Sahri, Wencheng Yang, Craig Valli, Victor R. Kebande Jan 2021

A Review Of Security Standards And Frameworks For Iot-Based Smart Environments, Nickson M. Karie, Nor Masri Sahri, Wencheng Yang, Craig Valli, Victor R. Kebande

Research outputs 2014 to 2021

Assessing the security of IoT-based smart environments such as smart homes and smart cities is becoming fundamentally essential to implementing the correct control measures and effectively reducing security threats and risks brought about by deploying IoT-based smart technologies. The problem, however, is in finding security standards and assessment frameworks that best meets the security requirements as well as comprehensively assesses and exposes the security posture of IoT-based smart environments. To explore this gap, this paper presents a review of existing security standards and assessment frameworks which also includes several NIST special publications on security techniques highlighting their primary areas of …


Cross-Education And Detraining Effects Of Eccentric Vs. Concentric Resistance Training Of The Elbow Flexors, Shigeru Sato, Riku Yoshida, Ryosuke Kiyono, Kaoru Yahata, Koki Yasaka, Kazunori (Ken) Nosaka, Masatoshi Nakamura Jan 2021

Cross-Education And Detraining Effects Of Eccentric Vs. Concentric Resistance Training Of The Elbow Flexors, Shigeru Sato, Riku Yoshida, Ryosuke Kiyono, Kaoru Yahata, Koki Yasaka, Kazunori (Ken) Nosaka, Masatoshi Nakamura

Research outputs 2014 to 2021

Background: Unilateral resistance training increases the strength of the contralateral non-trained homologous muscles known as the cross-education effect. We tested the hypothesis that unilateral eccentric resistance training (ET) would induce greater and longer-lasting cross-education effect when compared with concentric resistance training (CT). Methods: Young (20–23 y) participants were allocated to ET (5 males, 4 females) or CT (5 males, 4 females) group that performed unilateral progressive ET or CT of the elbow flexors, twice a week for 5 weeks (10 sessions) followed by a 5-week detraining, and control group (7 males, 6 females) that did not perform any training. Maximum …


Video Analysis And Verification Of Direct Head Impacts Recorded By Wearable Sensors In Junior Rugby League Players, Lauchlan Carey, Douglas P. Terry, Andrew S. Mcintosh, Peter Stanwell, Grant L. Iverson, Andrew J. Gardner Jan 2021

Video Analysis And Verification Of Direct Head Impacts Recorded By Wearable Sensors In Junior Rugby League Players, Lauchlan Carey, Douglas P. Terry, Andrew S. Mcintosh, Peter Stanwell, Grant L. Iverson, Andrew J. Gardner

Research outputs 2014 to 2021

Background: Rugby league is a high-intensity collision sport that carries a risk of concussion. Youth athletes are considered to be more vulnerable and take longer to recover from concussion than adult athletes. Purpose: To review head impact events in elite-level junior representative rugby league and to verify and describe characteristics of X-patchTM-recorded impacts via video analysis. Study Design: Observational case series. Methods: The X-patchTM was used on twenty-one adolescent players (thirteen forwards and eight backs) during a 2017 junior representative rugby league competition. Game-day footage, recorded by a trained videographer from a single camera, was synchronised with X-patchTM-recorded timestamped events. …


Proteome And Nutritional Shifts Observed In Hordein Double-Mutant Barley Lines, Utpal Bose, Angéla Juhász, Ronald Yu, Mahya Bahmani, Keren Byrne, Malcolm Blundell, James A. Broadbent, Crispin A. Howitt, Michelle L. Colgrave Jan 2021

Proteome And Nutritional Shifts Observed In Hordein Double-Mutant Barley Lines, Utpal Bose, Angéla Juhász, Ronald Yu, Mahya Bahmani, Keren Byrne, Malcolm Blundell, James A. Broadbent, Crispin A. Howitt, Michelle L. Colgrave

Research outputs 2014 to 2021

Lysine is the most limiting essential amino acid in cereals, and efforts have been made over the decades to improve the nutritional quality of these grains by limiting storage protein accumulation and increasing lysine content, while maintaining desired agronomic traits. The single lys3 mutation in barley has been shown to significantly increase lysine content but also reduces grain size. Herein, the regulatory effect of the lys3 mutation that controls storage protein accumulation as well as a plethora of critically important processes in cereal seeds was investigated in double mutant barley lines. This was enabled through the generation of three hordein …


Chinese International Students In The United States: The Interplay Of Students’ Acculturative Stress, Academic Standing, And Quality Of Life, Zhaohui Su, Dean Mcdonnell, Feng Shi, Bin Liang, Xiaoshan Li, Jun Wen, Yuyang Cai, Yu-Tao Xiang, Ling Yang Jan 2021

Chinese International Students In The United States: The Interplay Of Students’ Acculturative Stress, Academic Standing, And Quality Of Life, Zhaohui Su, Dean Mcdonnell, Feng Shi, Bin Liang, Xiaoshan Li, Jun Wen, Yuyang Cai, Yu-Tao Xiang, Ling Yang

Research outputs 2014 to 2021

Background: Acculturation could cause grave health consequences in international students. However, there is a shortage of research into how acculturative stress might affect international students’ quality of life in light of their academic standing and experience. The lack of research is particularly pronounced among Chinese international students, representing the largest body of international students studying in the United States (U.S.). Thus, to bridge the research gap, this study aims to examine the interplay between international students’ acculturative stress, academic standing, and quality of life among a nationally representative sample of Chinese international students studying in the United States. Methods: An …


Enhanced Oil Recovery By Hydrophilic Silica Nanofluid: Experimental Evaluation Of The Impact Of Parameters And Mechanisms On Recovery Potential, Tariq A. Chandio, Muhammad A. Manan, Khalil R. Memon, Ghulam Abbas, Ghazanfer R. Abbasi Jan 2021

Enhanced Oil Recovery By Hydrophilic Silica Nanofluid: Experimental Evaluation Of The Impact Of Parameters And Mechanisms On Recovery Potential, Tariq A. Chandio, Muhammad A. Manan, Khalil R. Memon, Ghulam Abbas, Ghazanfer R. Abbasi

Research outputs 2014 to 2021

Nanofluids as an EOR technique are reported to enhance oil recoveries. Among all the nanomaterial silica with promising lab results, economic and environmental acceptability are an ideal material for future applications. Despite the potential to enhance recoveries, understanding the two-fold impact of parameters such as concentration, salinity, stability, injection rate, and irreproducibility of results has arisen ambiguities that have delayed field applications. This integrated study is conducted to ascertain two-fold impacts of concentration and salinity on recovery and stability and evaluates corresponding changes in the recovery mechanism with variance in the parameters. Initially, silica nanofluids’ recovery potential was evaluated by …


Comparison Of Experiences In Two Birth Cohorts Comprising Young Families With Children Under Four Years During The Initial Covid-19 Lockdown In Australia And The Uk: A Qualitative Study, Lisa Y. Gibson, Bridget Lockyer, Josie Dickerson, Charlotte Endacott, Sally Bridges, Rosemary R. C. Mceachan, Kate E. Pickett, Sarah Whalan, Natasha L. Bear, Desiree T. Silva, Susan L. Prescott, Jacqueline A. Davis Jan 2021

Comparison Of Experiences In Two Birth Cohorts Comprising Young Families With Children Under Four Years During The Initial Covid-19 Lockdown In Australia And The Uk: A Qualitative Study, Lisa Y. Gibson, Bridget Lockyer, Josie Dickerson, Charlotte Endacott, Sally Bridges, Rosemary R. C. Mceachan, Kate E. Pickett, Sarah Whalan, Natasha L. Bear, Desiree T. Silva, Susan L. Prescott, Jacqueline A. Davis

Research outputs 2014 to 2021

This study aims to understand the experience and impact of the initial COVID-19 lock-down in young families with children aged below 4 years. Free text questions were administered to participants in the ORIGINS (Australia) and Born in Bradford (UK) cohort studies to collect qualitative information on worries, concerns and enjoyable experiences during the pandemic. A total of 903 (400 for ORIGINS and 503 for BiB) participants completed the two surveys during April 2020. Despite varying in geography, levels of socio-economic disadvantage and their situational context during the pandemic, respondents from both cohorts reported similar worries and challenges during the lockdown …


Biometrics For Internet‐Of‐Things Security: A Review, Wencheng Yang, Song Wang, Nor Masri Sahri, Nickson M. Karie, Mohiuddin Ahmed, Craig Valli Jan 2021

Biometrics For Internet‐Of‐Things Security: A Review, Wencheng Yang, Song Wang, Nor Masri Sahri, Nickson M. Karie, Mohiuddin Ahmed, Craig Valli

Research outputs 2014 to 2021

The large number of Internet‐of‐Things (IoT) devices that need interaction between smart devices and consumers makes security critical to an IoT environment. Biometrics offers an interesting window of opportunity to improve the usability and security of IoT and can play a significant role in securing a wide range of emerging IoT devices to address security challenges. The purpose of this review is to provide a comprehensive survey on the current biometrics research in IoT security, especially focusing on two important aspects, authentication and encryption. Regarding authentication, contemporary biometric‐based authentication systems for IoT are discussed and classified based on different biometric …


Potential Of Sorghum Polyphenols To Prevent And Treat Alzheimer's Disease: A Review Article, Nasim Rezaee, Warnakulasuriya Mary Ann Dipika Fernando, Eugene Hone, Hamid R. Sohrabi, Stuart K. Johnson, Stuart Gunzburg, Ralph Martins Jan 2021

Potential Of Sorghum Polyphenols To Prevent And Treat Alzheimer's Disease: A Review Article, Nasim Rezaee, Warnakulasuriya Mary Ann Dipika Fernando, Eugene Hone, Hamid R. Sohrabi, Stuart K. Johnson, Stuart Gunzburg, Ralph Martins

Research outputs 2014 to 2021

Alzheimer’s disease (AD) is characterized by the excessive deposition of extracellular amyloid-beta peptide (Aβ) and the build-up of intracellular neurofibrillary tangles containing hyperphosphorylated tau proteins. This leads to neuronal damage, cell death and consequently results in memory and learning impairments leading to dementia. Although the exact cause of AD is not yet clear, numerous studies indicate that oxidative stress, inflammation, and mitochondrial dysfunction significantly contribute to its onset and progression. There is no effective therapeutic approach to stop the progression of AD and its associated symptoms. Thus, early intervention, preferably, pre-clinically when the brain is not significantly affected, is a …


Inconsistent Use Of Resistance Exercise Names In Research Articles: A Brief Note, James L. Nuzzo Jan 2021

Inconsistent Use Of Resistance Exercise Names In Research Articles: A Brief Note, James L. Nuzzo

Research outputs 2014 to 2021

Academic fields require standard nomenclature to communicate concepts effectively. Previous research has documented resistance training exercises are named inconsistently. This inconsistent use has been observed among fitness professionals and within resistance training textbooks. The purpose of the current note was to explore inconsistent use of resistance training exercise names in scientific articles. Keyword searches were performed in PubMed to identify articles that referred to 4 different resistance training exercises. The search was limited to titles and abstracts of articles published between 1960 and 2020. For exercise 1, "shoulder press," "overhead press," and "military press" were searched. For exercise 2, "arm …


Adaptations To Post-Exercise Cold Water Immersion: Friend, Foe, Or Futile?, Mohammed Ihsan, Chris R. Abbiss, Robert Allan Jan 2021

Adaptations To Post-Exercise Cold Water Immersion: Friend, Foe, Or Futile?, Mohammed Ihsan, Chris R. Abbiss, Robert Allan

Research outputs 2014 to 2021

In the last decade, cold water immersion (CWI) has emerged as one of the most popular post-exercise recovery strategies utilized amongst athletes during training and competition. Following earlier research on the effects of CWI on the recovery of exercise performance and associated mechanisms, the recent focus has been on how CWI might influence adaptations to exercise. This line of enquiry stems from classical work demonstrating improved endurance and mitochondrial development in rodents exposed to repeated cold exposures. Moreover, there was strong rationale that CWI might enhance adaptations to exercise, given the discovery, and central role of peroxisome proliferator-activated receptor gamma …


Influence Of The Covid-19 Pandemic On Mood And Training In Australian Community Tennis Players, Mitchell Turner, Philipp Beranek, Shane L. Rogers, Kazunori Nosaka, Olivier Girard, Travis Cruickshank Jan 2021

Influence Of The Covid-19 Pandemic On Mood And Training In Australian Community Tennis Players, Mitchell Turner, Philipp Beranek, Shane L. Rogers, Kazunori Nosaka, Olivier Girard, Travis Cruickshank

Research outputs 2014 to 2021

The COVID-19 outbreak has led to the implementation of strict restrictions in Australia, which have severely impacted sporting activities. Tennis is played by 6.2% of the population within the Oceania region, and is a valuable sport for maintaining social, mental, and physical health. Current literature indicates the COVID-19 pandemic has negatively affected the mental health of Australian residents. The aim of this study was to investigate changes in training and match play due to the outbreak, and its effects on emotional well-being of Australian senior tennis players. Additionally, explore any differences between middle aged (41-60 years) and senior (61 years …


Pattern And Degree Of Individual Brain Atrophy Predicts Dementia Onset In Dominantly Inherited Alzheimer's Disease, Ophir Keret, Adam M. Staffaroni, John M. Ringman, Yann Cobigo, Sheng-Yang M. Goh, Amy Wolf, Isabel Elaine Allen, Stephen Salloway, Jasmeer Chhatwal, Adam M. Brickman, Dolly Reyes-Dumeyer, Randal J. Bateman, Tammie L.S. Benzinger, John C. Morris, Beau M. Ances, Nelly Joeseph-Mathurin, Richard J. Perrin, Brian A. Gordon, Johannes Levin, Jonathan Voglein, Mathias Jucker, Christian La Fougere, Ralph N. Martins, Hamid R. Sohrabi, Kevin Taddei, Victor L. Villemagne, Peter R. Schofield, William S. Brooks, Michael Fulham, Colin L. Masters, Bernardino Ghetti, Andrew J. Saykin, Clifford R. Jack, Neill R. Graff-Radford, Michael Weiner, David M. Cash, Ricardo F. Allegri, Patricio Chrem, Su Yi, Bruce L. Miller, Gil D. Rabinovici, Howard J. Rosen, Dominantly Inherited Alzheimer Network Jan 2021

Pattern And Degree Of Individual Brain Atrophy Predicts Dementia Onset In Dominantly Inherited Alzheimer's Disease, Ophir Keret, Adam M. Staffaroni, John M. Ringman, Yann Cobigo, Sheng-Yang M. Goh, Amy Wolf, Isabel Elaine Allen, Stephen Salloway, Jasmeer Chhatwal, Adam M. Brickman, Dolly Reyes-Dumeyer, Randal J. Bateman, Tammie L.S. Benzinger, John C. Morris, Beau M. Ances, Nelly Joeseph-Mathurin, Richard J. Perrin, Brian A. Gordon, Johannes Levin, Jonathan Voglein, Mathias Jucker, Christian La Fougere, Ralph N. Martins, Hamid R. Sohrabi, Kevin Taddei, Victor L. Villemagne, Peter R. Schofield, William S. Brooks, Michael Fulham, Colin L. Masters, Bernardino Ghetti, Andrew J. Saykin, Clifford R. Jack, Neill R. Graff-Radford, Michael Weiner, David M. Cash, Ricardo F. Allegri, Patricio Chrem, Su Yi, Bruce L. Miller, Gil D. Rabinovici, Howard J. Rosen, Dominantly Inherited Alzheimer Network

Research outputs 2014 to 2021

Introduction: Asymptomatic and mildly symptomatic dominantly inherited Alzheimer's disease mutation carriers (DIAD-MC) are ideal candidates for preventative treatment trials aimed at delaying or preventing dementia onset. Brain atrophy is an early feature of DIAD-MC and could help predict risk for dementia during trial enrollment. Methods: We created a dementia risk score by entering standardized gray-matter volumes from 231 DIAD-MC into a logistic regression to classify participants with and without dementia. The score's predictive utility was assessed using Cox models and receiver operating curves on a separate group of 65 DIAD-MC followed longitudinally. Results: Our risk score separated asymptomatic versus demented …


Whole Fat Dairy Products Do Not Adversely Affect Adiposity Or Cardiometabolic Risk Factors Inchildren In The Milky Way Study: A Double Blind Randomized Controlled Pilot Study, Analise Nicholl, Kane Deering, Kate J. Evelegh, Philippa Lyons-Wall, David Lawrence, Trevor A. Mori, Mario Kratz, Therese O'Sullivan Jan 2021

Whole Fat Dairy Products Do Not Adversely Affect Adiposity Or Cardiometabolic Risk Factors Inchildren In The Milky Way Study: A Double Blind Randomized Controlled Pilot Study, Analise Nicholl, Kane Deering, Kate J. Evelegh, Philippa Lyons-Wall, David Lawrence, Trevor A. Mori, Mario Kratz, Therese O'Sullivan

Research outputs 2014 to 2021

Background

Limited evidence supports the common public health guideline that children > 2 y of age should consume dairy with reduced fat content.

Objectives

We aimed to investigate the effects of whole-fat compared with reduced-fat dairy intake on measures of adiposity and biomarkers of cardiometabolic risk in healthy 4- to 6-y-old children.

Methods

The Milky Way Study enrolled 49 children (mean ± SD age: 5.2 ± 0.9 y; 47% girls) who were habitual consumers of whole-fat dairy, then randomly assigned them in a double-blind fashion to remain on whole-fat dairy or switch their dairy consumption to reduced-fat products for 3 mo. …


The Psychosocial Impact Of Rare Diseases Among Children And Adolescents Attending Mainstream Schools In Western Australia, Esther A. Adama, Diana Arabiat, Mandie Foster, Ebenezer Afrifa-Yamoah, K. Runions, R. Vithiatharan, A. Lin Jan 2021

The Psychosocial Impact Of Rare Diseases Among Children And Adolescents Attending Mainstream Schools In Western Australia, Esther A. Adama, Diana Arabiat, Mandie Foster, Ebenezer Afrifa-Yamoah, K. Runions, R. Vithiatharan, A. Lin

Research outputs 2014 to 2021

Living with a long-term medical condition is associated with heightened risk for mental health and psychosocial difficulties, but further research is required on this risk for children and adolescents with a rare disease in the educational setting. The aim of this study is to describe parents’ perceptions of the psychosocial impact of rare diseases on their school-aged children in Western Australia. A cross-sectional survey of 41 parents of school-aged children and adolescents diagnosed with a rare disease completed an online questionnaire. Questions related to their perceptions of health-related stigma, bullying, social competencies and mental health difficulties faced by their child. …


Exercise Effects On Muscle Quality In Older Adults: A Systematic Review And Meta-Analysis, Régis Radaelli, Dennis Taaffe, Robert Newton, Daniel A. Galvao, Pedro Lopez Jan 2021

Exercise Effects On Muscle Quality In Older Adults: A Systematic Review And Meta-Analysis, Régis Radaelli, Dennis Taaffe, Robert Newton, Daniel A. Galvao, Pedro Lopez

Research outputs 2014 to 2021

To systematically review and analyse the effects of exercise on morphological and neuromuscular muscle quality (MQ) outcomes in older adults and assess a range of possible moderators that may affect the impact of exercise on MQ outcomes. Using PRISMA guidelines, randomised controlled trials were searched in CINAHL, EMBASE, LILACS, PubMed, SciELO, Web of Science, MedNar, OpenGrey and OpenThesis databases. Eligible trials examined the effects of exercise interventions on morphological and neuromuscular MQ in older adults ( ≥ 60 years). Twenty-one trials (n = 973 participants) were included. Exercise significantly improved morphological MQ (effect size (ES) = 0.32, 95% CI 0.13–0.51, …


Heritability Enrichment Of Immunoglobulin G N-Glycosylation In Specific Tissues, Xingang Li, Hao Wang, Yahong Zhu, Weijie Cao, Song Manshu, Youxin Wang, Haifeng Hou, Minglin Lang, Xiuhua Guo, Xuerui Tan, Jingdong J. Han, Wei Wang Jan 2021

Heritability Enrichment Of Immunoglobulin G N-Glycosylation In Specific Tissues, Xingang Li, Hao Wang, Yahong Zhu, Weijie Cao, Song Manshu, Youxin Wang, Haifeng Hou, Minglin Lang, Xiuhua Guo, Xuerui Tan, Jingdong J. Han, Wei Wang

Research outputs 2014 to 2021

Genome-wide association studies (GWAS) have identified over 60 genetic loci associated with immunoglobulin G (IgG) N-glycosylation; however, the causal genes and their abundance in relevant tissues are uncertain. Leveraging data from GWAS summary statistics for 8,090 Europeans, and large-scale expression quantitative trait loci (eQTL) data from the genotype-tissue expression of 53 types of tissues (GTEx v7), we derived a linkage disequilibrium score for the specific expression of genes (LDSC-SEG) and conducted a transcriptome-wide association study (TWAS). We identified 55 gene associations whose predicted levels of expression were significantly associated with IgG N-glycosylation in 14 tissues. Three working scenarios, i.e., tissue-specific, …


Organizational Factors Associated With Health Worker Protection During The Covid-19 Pandemic In Four Provinces Of South Africa, Muzimkhulu Zungu, Kuku Voyi, Nosimilo Mlangeni, Saiendhra Vasudevan Moodley, Jonathan Ramodike, Nico Claassen, Elizabeth Wilcox, Nkululeko Thunzi, Annalee Yassi, Jerry Spiegel, Molebogeng Malotle Jan 2021

Organizational Factors Associated With Health Worker Protection During The Covid-19 Pandemic In Four Provinces Of South Africa, Muzimkhulu Zungu, Kuku Voyi, Nosimilo Mlangeni, Saiendhra Vasudevan Moodley, Jonathan Ramodike, Nico Claassen, Elizabeth Wilcox, Nkululeko Thunzi, Annalee Yassi, Jerry Spiegel, Molebogeng Malotle

Research outputs 2014 to 2021

Background: Health workers, in short supply in many low-and-middle-income countries, are at increased risk of SARS-CoV-2 infection. This study aimed to assess how South Africa, prepared to protect its health workers from SARS-CoV-2 infection. Methods: This was a cross-sectional study design applying participatory action research in four provinces of South Africa. A semi-structured questionnaire and a qualitative observational HealthWISE walkthrough risk assessment was carried out to collect data on occupational safety and health (OSH) systems in 45 hospitals across four provinces to identify factors associated with health worker protection. Adapting the International Labour Organization (ILO) and World Health Organization (WHO) …


Kinetic Study Of Product Distribution Using Various Data-Driven And Statistical Models For Fischer-Tropsch Synthesis, Yixiao Wang, Jing Hu, Xiyue Zhang, Abubakar Yusuf, Binbin Qi, Huan Jin, Yiyang Liu, Jun He, Yunshan Wang, Gang Yang, Yong Sun Jan 2021

Kinetic Study Of Product Distribution Using Various Data-Driven And Statistical Models For Fischer-Tropsch Synthesis, Yixiao Wang, Jing Hu, Xiyue Zhang, Abubakar Yusuf, Binbin Qi, Huan Jin, Yiyang Liu, Jun He, Yunshan Wang, Gang Yang, Yong Sun

Research outputs 2014 to 2021

Three modeling techniques, namely, a radial basis function neural network (RBFNN), a comprehensive kinetic with genetic algorithm (CKGA), and a response surface methodology (RSM), were used to study the kinetics of Fischer-Tropsch (FT) synthesis. Using a 29 × 37 (4 independent process parameters as inputs and corresponding 36 responses as outputs) matrix with total 1073 data sets for data training through RBFNN, the established model is capable of predicting hydrocarbon product distribution i.e., the paraffin formation rate (C2-C15) and the olefin to paraffin ratio (OPR) within acceptable uncertainties. With additional validation data sets (15 × 36 matrix with total 540 …


Open Data From The First And Second Observing Runs Of Advanced Ligo And Advanced Virgo, Ligo Scientific Collaboration, Virgo Collaboration, Tiffany Z. Summerscales Jan 2021

Open Data From The First And Second Observing Runs Of Advanced Ligo And Advanced Virgo, Ligo Scientific Collaboration, Virgo Collaboration, Tiffany Z. Summerscales

Faculty Publications

Advanced LIGO and Advanced Virgo are monitoring the sky and collecting gravitational-wave strain data with sufficient sensitivity to detect signals routinely. In this paper we describe the data recorded by these instruments during their first and second observing runs. The main data products are gravitational-wave strain time series sampled at 16384 Hz. The datasets that include this strain measurement can be freely accessed through the Gravitational Wave Open Science Center at http://gw-openscience.org, together with data-quality information essential for the analysis of LIGO and Virgo data, documentation, tutorials, and supporting software.


Association Between Transcription Factor 7-Like-2 Polymorphisms And Type 2 Diabetes Mellitus In A Ghanaian Population, Christian Obirikorang, Evans Asamoah Adu, Enoch Odame Anto, Emmanuel Acheampong, Lawrence Quaye, Brodrick Yeboah Amoah, Max Efui Annani-Akollor, Aaron Siaw Kwakye, Foster Fokuoh, Michael Appiah, Eric Nana Yaw Nyarko, Freeman Aidoo, Eric Adua, Ebenezer Afrifa-Yamoah, Lois Balmer, Wei Wang Jan 2021

Association Between Transcription Factor 7-Like-2 Polymorphisms And Type 2 Diabetes Mellitus In A Ghanaian Population, Christian Obirikorang, Evans Asamoah Adu, Enoch Odame Anto, Emmanuel Acheampong, Lawrence Quaye, Brodrick Yeboah Amoah, Max Efui Annani-Akollor, Aaron Siaw Kwakye, Foster Fokuoh, Michael Appiah, Eric Nana Yaw Nyarko, Freeman Aidoo, Eric Adua, Ebenezer Afrifa-Yamoah, Lois Balmer, Wei Wang

Research outputs 2014 to 2021

Type 2 diabetes mellitus (T2DM) has been strongly associated with single nucleotide polymorphisms (SNPs) in the TCF7L2 gene. This study investigated the association between rs12255372, rs7903146 in the TCF7L2 gene and T2DM in a Ghanaian population. A case-control study design was used for this study. A total of 106 T2DM patients and 110 control participants were selected. Basic data collected included body mass index, blood pressure and socio-demographics. Fasting blood samples were collected and processed for: serum lipid analysis, plasma glucose estimation and plasma HbA1c estimation. Parts of the whole blood samples were used for DNA extraction using a modified …


Customer Value Creation For The Emerging Market Middle Class: Perspectives From Case Studies In India, Rifat Sharmelly, Anton Klarin Jan 2021

Customer Value Creation For The Emerging Market Middle Class: Perspectives From Case Studies In India, Rifat Sharmelly, Anton Klarin

Research outputs 2014 to 2021

This paper examines the customer value creation framework and discusses the design of the key elements for product development in emerging markets. A scientometric/bibliometric scoping literature review identifies a clear gap in the current research in studying prerequisites for customer value creation in emerging market contexts. Observing experiences of Daikin and Renault in the context of India, the purpose of this paper is to identify value creation strategic choices following which comprehensive customer value offerings in products and services can be successfully created by firms across the four facets of the framework in emerging markets. Value creation strategies include having …


Prevalence Of Abdominal Obesity In Chinese Middle-Aged And Older Adults With A Normal Body Mass Index And Its Association With Type 2 Diabetes Mellitus: A Nationally Representative Cohort Study From 2011 To 2018, Xuan Chen, Mingrui Duan, Rui Hou, Manqi Zheng, Haibin Li, Manjot Singh, Changwei Li, Kuo Liu, Feng Zhang, Xinghua Yang, Yanxia Luo, Yan He, Lijuan Wu, Deqiang Zheng Jan 2021

Prevalence Of Abdominal Obesity In Chinese Middle-Aged And Older Adults With A Normal Body Mass Index And Its Association With Type 2 Diabetes Mellitus: A Nationally Representative Cohort Study From 2011 To 2018, Xuan Chen, Mingrui Duan, Rui Hou, Manqi Zheng, Haibin Li, Manjot Singh, Changwei Li, Kuo Liu, Feng Zhang, Xinghua Yang, Yanxia Luo, Yan He, Lijuan Wu, Deqiang Zheng

Research outputs 2014 to 2021

Background: Few studies have focused on the prevalence of abdominal obesity in Chinese middle-aged and older adults with a normal body mass index (BMI). Furthermore, it is still unclear whether abdominal obesity is an independent risk factor for type 2 diabetes mellitus (T2DM). Participants with a normal BMI are usually neglected during assessments of abdominal obesity-associated T2DM risk since the current recommendations for medical interventions are mainly focused on overall body mass index rather than fat deposition patterns. Methods: In this study, 7942 normal-BMI participants aged over 45 years from the China Health and Retirement Longitudinal Study were included to …


Psychological Distress And Quality Of Life Following Provision Of Vascular Imaging Results Of The Coronary And Carotid Arteries To Asymptomatic Adults: A Scoping Review Protocol, Reindolf Anokye, Ben Jackson, James Dimmock, Joanne M. Dickson, Lauren C. Blekkenhorst, Jonathan M. Hodgson, Joshua R. Lewis, Mandy Stanley Jan 2021

Psychological Distress And Quality Of Life Following Provision Of Vascular Imaging Results Of The Coronary And Carotid Arteries To Asymptomatic Adults: A Scoping Review Protocol, Reindolf Anokye, Ben Jackson, James Dimmock, Joanne M. Dickson, Lauren C. Blekkenhorst, Jonathan M. Hodgson, Joshua R. Lewis, Mandy Stanley

Research outputs 2014 to 2021

Background: Non-invasive screening for atherosclerosis or asymptomatic cardiovascular disease of the coronary and carotid arteries is commonly undertaken, and research has been focussed on how results from these screenings lead to behaviour change. However, no review has focused on the effects of these results on psychological distress and health-related quality of life (HRQoL). This protocol will outline how a scoping review will be conducted to map all available evidence on psychological distress and/or HRQoL outcomes following the provision of vascular imaging results of the coronary and carotid arteries. Methods: Arksey and O’Malley’s (2005) framework subsequently enhanced by Levac et al. …


The Open Maritime Traffic Analysis Dataset, Martin Masek, Chiou Peng Lam, Travis Rybicki, Jacob Snell, Daniel Wheat, Luke Kelly, Damion Glassborow, Cheryl Smith-Gander Jan 2021

The Open Maritime Traffic Analysis Dataset, Martin Masek, Chiou Peng Lam, Travis Rybicki, Jacob Snell, Daniel Wheat, Luke Kelly, Damion Glassborow, Cheryl Smith-Gander

Research outputs 2014 to 2021

Ships traverse the world’s oceans for a diverse range of reasons, including the bulk transportation of goods and resources, carriage of people, exploration and fishing. The size of the oceans and the fact that they connect a multitude of different countries provide challenges in ensuring the safety of vessels at sea and the prevention of illegal activities. To assist with the tracking of ships at sea, the International Maritime Organisation stipulates the use of the Automatic Identification System (AIS) on board ships. The AIS system periodically broadcasts details of a ship’s position, speed and heading, along with other parameters corresponding …


Nursing And Allied Health Staff Perceptions And Experiences Of A Volunteer Stroke Peer Support Program: A Qualitative Study, Rosemary Saunders, Kien Chan, Renée M. Graham, Elena Adams, Caroline E. Bulsara, Karla Seaman, Marcella Cranny-Connolly Jan 2021

Nursing And Allied Health Staff Perceptions And Experiences Of A Volunteer Stroke Peer Support Program: A Qualitative Study, Rosemary Saunders, Kien Chan, Renée M. Graham, Elena Adams, Caroline E. Bulsara, Karla Seaman, Marcella Cranny-Connolly

Research outputs 2014 to 2021

Purpose: Stroke brings about physical, cognitive, and psychosocial changes and, conse-quently, many stroke survivors feel underprepared for the transition from hospital to home. Nursing and allied health staff have a key role in stroke rehabilitation. Peer support programs have been found effective in supporting stroke survivors, alongside hospital staff caring for stroke patients, by providing experiential knowledge that staff are not able to provide. Aim: This study explored the perceptions and experiences of nursing and allied health staff of a volunteer peer support program for stroke inpatients. Methods: This study utilised a qualitative, evaluative case study design. This study was …


Teachers’ Perceptions Of The Impact Of Covid-19 On Writing Instruction In Australia, Margaret K. Merga, Anabela Malpique, Saiyidi Mat Roni, Debora Valcan, Susan Ledger Jan 2021

Teachers’ Perceptions Of The Impact Of Covid-19 On Writing Instruction In Australia, Margaret K. Merga, Anabela Malpique, Saiyidi Mat Roni, Debora Valcan, Susan Ledger

Research outputs 2014 to 2021

Education interruption can influence educational outcomes for students, particularly those already experiencing disadvantage. Little is known about how education interruption caused by COVID-19 has influenced the literacy learning of Australian students. This article provides insights into the impact of COVID-19 related education interruption on writing instruction of primary school aged children from the perspectives of their teachers. Drawing on data from a single-stage mixed-methods survey tool, it explores extent of perception of an impact of COVID-19 writing instruction in Australia, as well as capturing data on the nature of this perceived impact. As expected, the COVID-19 pandemic had an impact …