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2021

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The Physiological Factors Of Diabetes And Their Effect On The Cognitive And Emotional Functioning In Older Populations: A Secondary Data Analysis, Celeste Anahi Alvidrez Dec 2021

The Physiological Factors Of Diabetes And Their Effect On The Cognitive And Emotional Functioning In Older Populations: A Secondary Data Analysis, Celeste Anahi Alvidrez

Open Access Theses & Dissertations

Background: The rates of Type 2 Diabetes (T2D) have increased over the past 20 years in all age groups. The physiological factors that underlie T2D could have impact on specific brain pathways that support cognitive and emotional functioning. Aims and Objective: The goal of this study was to examine whether older Mexican American individuals with a history of T2D were more likely to develop later cognitive impairment and/or depression. Hypotheses: It was predicted that elderly participants (mean age at time of interview = 87.87 years) with a history of T2D onset prior to age 65, are more likely to have …


Examination Of The Association Between C - Reactive Protein(Crp) And Covid-19 Infection Severity And Length Of Hospitalization, Abdulahi Aremu Ayanwale Dec 2021

Examination Of The Association Between C - Reactive Protein(Crp) And Covid-19 Infection Severity And Length Of Hospitalization, Abdulahi Aremu Ayanwale

Open Access Theses & Dissertations

Chronic stress can lead to many systemic complications and low-grade systemic inflammation including increased levels of inflammatory cytokines, such as C-reactive protein (CRP). CRP is a marker of systemic inflammation and is associated with depression and perceived stress. Elevations can result in ineffective immune responses, thereby increasing the risk of complications and mortality from infections. Recent evidence suggests that uncontrolled inflammatory responses associated with COVID 19 are a major determinant of disease severity.  The COVID 19 is transmitted from one person to another through droplets from coughing, sneezing, talking, touching droplets on surfaces and contamination by hand-to-mouth routes. The mechanism …


Survey Of Ncaa Athletic Trainers’ Administration Of The National Wrestling Coaches Association Weight Certification Program, Samuel Konrath Dec 2021

Survey Of Ncaa Athletic Trainers’ Administration Of The National Wrestling Coaches Association Weight Certification Program, Samuel Konrath

All Graduate Plan B and other Reports, Spring 1920 to Spring 2023

Context: The National Collegiate Athletic Association (NCAA) implemented a minimum weight certification program in 1997 to help protect wrestlers from dangerous weight loss practices. Despite nearly a quarter of a century of this program, there is no published research detailing the implementation of it.

Objective: Determine how the NCAA minimum weight certification is being implemented across Division I programs.

Design: Cross-sectional study

Setting: Survey

Patients or Other Participants: A total of 35 (45.5%) of 77 NCAA division I wrestling athletic trainers responded to the survey.

Main Outcome Measure(s): Survey data on how the NCAA minimum weight certification program was implemented …


Transfer Effects Of A Multiple-Joint Isokinetic Eccentric Training Intervention To Nontraining-Specific Traditional Muscle Function Measures, Steven Spencer Dec 2021

Transfer Effects Of A Multiple-Joint Isokinetic Eccentric Training Intervention To Nontraining-Specific Traditional Muscle Function Measures, Steven Spencer

All Graduate Plan B and other Reports, Spring 1920 to Spring 2023

The transfer effects of isokinetic, eccentric-only resistance training programs on non-specific measures of muscle function such as isometric peak force, isokinetic concentric peak force and dynamic constant external resistance 1-repetition maximal strength (DCER 1RM) have been researched extensively in a single joint context, yielding mixed results. However, investigations involving multiple-joint isokinetic eccentric-only training models have been sparse. The purpose of this study was to investigate the transfer effects of a short-term multiple-joint isokinetic eccentric leg press (Eccentron) training program on several measures of lower-body strength and performance. Fifteen participants performed Eccentron training three times/week for four weeks and were evaluated …


Relationship Between Mothers’/Caregivers’ Reported Learning Difficulty And Internalizing Symptoms (Anxiety And Depression) Of Children Aged 5–17 Years In Ghana, Queen Angela Norman, Nutifafa Eugene Yaw Dey, Kenneth Owusu Ansah, Francis Arthur-Holmes, Henry Ofori Duah, Pascal Agbadi Dec 2021

Relationship Between Mothers’/Caregivers’ Reported Learning Difficulty And Internalizing Symptoms (Anxiety And Depression) Of Children Aged 5–17 Years In Ghana, Queen Angela Norman, Nutifafa Eugene Yaw Dey, Kenneth Owusu Ansah, Francis Arthur-Holmes, Henry Ofori Duah, Pascal Agbadi

College of Nursing Faculty Research and Publications

Studies have reported different factors associated with anxiety and depression among children and adolescents. However, studies examining the relationship between learning difficulties and internalizing symptoms of Ghanaian children is scarce. The only study available found that 152 students with learning difficulties who visited a psychology clinic for psychological assessment had high levels of stress and anxiety (Asare & Danquah, 2016). While the study provided preliminary evidence of the relationship between learning difficulties and internalizing symptoms, it had some methodological challenges. For instance, the study used a relatively smaller sample size and subsampled children in Accra. Our study used a nationally …


Intraspecific Variation In Prey Susceptibility Mediates The Consumptive Effect Of Predation: A Case Study Of Yellowstone Elk And Wolves, Lacy M. Smith Dec 2021

Intraspecific Variation In Prey Susceptibility Mediates The Consumptive Effect Of Predation: A Case Study Of Yellowstone Elk And Wolves, Lacy M. Smith

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

The reintroduction of wolves (Canis lupus) to Yellowstone National Park starting in 1995 is an important case study for understanding the consequences of predation on a prey population. Simulation studies conducted prior to and shortly after wolf reintroduction predicted that wolf predation of elk (Cervus canadensis) would have a modest influence on elk abundance. Predation of elk by wolves has been well documented and elk have remained the primary prey for wolves despite a decline in elk abundance. I used two quantitative approaches to estimate the influence of wolf predation on adult female elk survival and …


The Plant Growth Promoting Ability Of The Microbiome Of Ceanothus Velutinus From The Intermountain West Region, Jyothsna Ganesh Dec 2021

The Plant Growth Promoting Ability Of The Microbiome Of Ceanothus Velutinus From The Intermountain West Region, Jyothsna Ganesh

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

Due to the ever-changing climate and deterioration of the earth’s ecosystem, environmental stresses like abiotic (drought, salinity) and biotic stresses (pathogen infection) gravely affected plant growth. Native plants are a great way of improving these effects on the urban landscape. They can be used as ornamental plants in landscaping as they are accustomed to their natural environment. The Center for Water-Efficient Landscaping at Utah State University has released a list of plants to be used for low water use landscaping. One such native plant is Ceanothus velutinus (snowbrush ceanothus). They are evergreen plants that can grow in dry and harsh …


Influence Of External Ph And Organic Acids On Internal Ph And Acid Anion Accumulation In Listeria Monocytogenes And Escherichia Coli, Savannah R. Branson Dec 2021

Influence Of External Ph And Organic Acids On Internal Ph And Acid Anion Accumulation In Listeria Monocytogenes And Escherichia Coli, Savannah R. Branson

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

Listeria monocytogenes and Escherichia coli are both among the most common microbial pathogens that cause foodborne illnesses and death. They both are capable of growing over a wide range of conditions. Organic acids are widely employed in the food industry to control growth of these pathogens to help prevent foodborne illnesses. There is substantial evidence that intracellular accumulation of organic acid anions is a major inhibitor to cell growth, and that many bacteria may combat anion accumulation by lowering their intracellular pH (pHi). In this study, we followed the accumulation of acid anion into the cell pellet and …


Impact Of Fish Oil On Intestinal Permeability, Inflammation, And Performance In Swine, Anthony Fernando Alberto Dec 2021

Impact Of Fish Oil On Intestinal Permeability, Inflammation, And Performance In Swine, Anthony Fernando Alberto

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

Our research examined the effects of fish oil supplementation on intestinal permeability, systemic inflammation and performance in piglets. An lipopolysaccharide (LPS) challenge was done to stimulate the synthesis and release of the cytokines, in an effort to mimic the immune response that piglets would have when facing stress or pathogen challenge. Fish oil increased feed intake but did not affect growth when compared to control. Total fatty acid digestibility increased by 6% when fish oil was included in the diet. Also, we observed a 16% increase on 16-carbon fatty acids digestibility. Fish oil did not affect the plasma …


Injection Of Iodoacetic Acid Into Pre-Rigor Bovine Muscle Simulates Dark Cutting Conditions, Jared Forrest Buhler Dec 2021

Injection Of Iodoacetic Acid Into Pre-Rigor Bovine Muscle Simulates Dark Cutting Conditions, Jared Forrest Buhler

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

Following the harvest of an animal, muscle will continue to produce energy in an attempt to stay alive, primarily through the pathway of glycolysis. This occurs in the form of anaerobic (oxygen-free) metabolism of glucose and glycogen, which causes the meat to acidify. This acidification process is important for proper meat quality development and when insufficient glycolysis occurs it can cause a meat defect known as dark cutting. This defect causes the color of the muscle to become very dark, increases the water-holding capacity of the meat, and causes it to feel firm and dry on the surface because the …


Enzymatic Synthesis Of Maltodextrin Fatty Acid Esters And Their Emulsion Stabilizing And Microbial Inhibitory Properties, Namhyeon Park Dec 2021

Enzymatic Synthesis Of Maltodextrin Fatty Acid Esters And Their Emulsion Stabilizing And Microbial Inhibitory Properties, Namhyeon Park

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

Food additives have been one of the traditional methods for preserving foods and are still in everyday use for multiple reasons. As the market size of processed foods grows, the use of food additives is increasing. Simultaneously, consumers try to avoid specific food additives or demand less processed foods because of several potential health concerns, suggesting the need for safe food additives.

In this environment, one group of food additives consisting of carbohydrates and fatty acids have received attention because of its nontoxicity and biodegradability with diverse functions. Notably, carbohydrate fatty acid compounds made of sucrose have been approved and …


Wear Behaviors Of Process Cheese With Varying Formulations And The Development Of Predictive Models On Shreddability, Jason Young Dec 2021

Wear Behaviors Of Process Cheese With Varying Formulations And The Development Of Predictive Models On Shreddability, Jason Young

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

Process Cheese is manufactured by grinding, mixing, and heating with agitation one or more of the same varieties of natural cheese with an emulsifying agent to create a cheese with desirable properties. After process cheese is made, it is often sliced or shredded. Some of its properties affect how well it can be sliced or shredded and can lead to loss of material due to cheese sticking to equipment or being too crumbly. The loss of material, called wear behavior can incur significant losses to cheese manufacturing operations. The purpose of this study was to produce process cheese formulations with …


Racial Diversity Of Texas School Teachers, Julie Ann Olguin-Phillips Dec 2021

Racial Diversity Of Texas School Teachers, Julie Ann Olguin-Phillips

Electronic Theses and Dissertations

There is a growing gap between the racial demographics of public-school teachers and their students. Teachers with demographic backgrounds similar to a school’s student population are often successful, particularly in Title 1 schools with high proportions of minority students; however, teacher turnover is high. The students in Texas public schools are a growing minority-majority population. Changes in the student body racial composition and other school-related variables could influence teacher workforce demographics. The focus of discussion of this quantitative research study is to determine the factors that predict the racial diversity of teachers in Texas high schools. The research questions addressed …


Effects Of Varying Warmup Stimuli On Running Economy, Connor Bigenho Dec 2021

Effects Of Varying Warmup Stimuli On Running Economy, Connor Bigenho

Electronic Theses and Dissertations

Purpose: The purpose of this study was to determine the effects of two potentiating warm-up stimuli (weighted-vest strides and plyometrics) on running economy (RE) over short (5-10 minutes) and longer durations (30+ minutes) of exercise in trained distance runners. Methods: Five recreationally trained male runners were recruited to participate in this study. Each trial consisted of a 10-min self-paced warm-up on the treadmill followed by baseline RE test and baseline leg-stiffness. This was immediately followed by one of two intervention warmup protocols. The protocols consisted of either a series of plyometric movements, 6 x 10-sec strides with a …


Assessing Freezing Effect On Kiwifruit Cultivars And Mapping Suitable Areas For Growing The Crop In Eastern Texas, Lais De Oliveira Machado Dec 2021

Assessing Freezing Effect On Kiwifruit Cultivars And Mapping Suitable Areas For Growing The Crop In Eastern Texas, Lais De Oliveira Machado

Electronic Theses and Dissertations

Kiwifruit is a perennial vine originating from China where it has been grown for centuries. In the United States, green kiwifruit (Actinidia deliciosa) is primarily produced commercially in California. They are fuzzy, green fleshed and well known in the marketplace. Kiwifruit plants require low to moderate soil pH, adequate winter chilling and adequate precipitation to guarantee plant development and good fructification. Actinidia chinesis or golden kiwifruit are smooth skinned, feature golden flesh and are a more recent introduction into the global market. Kiwifruit crops have attributes that favor production in east Texas, including low pest problems, current long …


Impact Of Planting Arrangement And Drill Row Spacing For Direct-Seeded, Delayed Flood Rice, Mary Jane Lytle Dec 2021

Impact Of Planting Arrangement And Drill Row Spacing For Direct-Seeded, Delayed Flood Rice, Mary Jane Lytle

Graduate Theses and Dissertations

Direct-seeding is the most frequently utilized planting practice in Arkansas and Mid-South rice (Oryza sativa L.) production. Enhanced plant density and more rapid rice canopy formation may result from the implementation of innovative plant arrangements and spacings. Studies were initiated in 2019 and continued into 2020 to examine different cultural management practice experiments, including evaluating the impacts of planting arrangement, row spacing, and seeding rates on rice stand density, canopy coverage, grain yield, and milling yield. These small-plot trials were conducted at two locations, a silt loam site and a clay site, representative of soils produced to rice in eastern …


Role Of Sex Differences On Cancer Cachexia Progression And Fibrosis During Cancer Cachexia Development, Wesley Haynie Dec 2021

Role Of Sex Differences On Cancer Cachexia Progression And Fibrosis During Cancer Cachexia Development, Wesley Haynie

Graduate Theses and Dissertations

Cancer cachexia is a multifactorial wasting syndrome characterized by losses in bodymass >5% and occurs in approximately 80% of all cancer patients. Chronic inflammation and fibrosis play roles in cancer cachexia and a greater understanding of these contributing pathways to this pathology will pave the way for potential therapeutic avenues. While inflammation and fibrosis have been researched in various models of cancer cachexia, little to no studies have been performed in both sexes as most previous studies focus on males. PURPOSE The purpose of these studies is to investigate the role of fibrosis on cancer cachexia development as well as …


Development And Evaluation Of Models For Hatchery-Mediated Infection Of Neonatal Broiler Chicks, Brittany Danielle Graham Dec 2021

Development And Evaluation Of Models For Hatchery-Mediated Infection Of Neonatal Broiler Chicks, Brittany Danielle Graham

Graduate Theses and Dissertations

Formaldehyde fumigation has been used to control the microbial load in commercial hatch cabinets. The hatch cabinet environment promotes replication and dissemination of both apathogenic and pathogenic microorganisms. As the microbial load increases during the hatching phase, formaldehyde eliminates airborne microorganisms circulating in the hatch cabinet environment. Due to the hazardous properties of formaldehyde, non-toxic alternatives to formaldehyde fumigation to control the microbial bloom in hatch cabinets are needed. The objectives of the present dissertation were to develop challenge models using singular or multiple microorganisms associated with the microbial bloom to simulate contamination that occurs in commercial hatch cabinets. Initially, …


Evaluation Of Two Neonatal Challenge Models For Broiler Chickens And Their Effects On Early Performance Parameters, Callie Selby Dec 2021

Evaluation Of Two Neonatal Challenge Models For Broiler Chickens And Their Effects On Early Performance Parameters, Callie Selby

Graduate Theses and Dissertations

Formaldehyde fumigation in poultry hatch cabinets has been utilized for sanitation of hatching eggs for over a century. Formaldehyde is utilized to minimize pathogenic microbes on the surface of the egg as well as the microbial bloom during the hatching process. While formaldehyde is effective, its use is regulated in the United States and Europe due to its carcinogenic nature. Formaldehyde has been shown to damage the cuticle of the egg, cause embryonic death, and damage the epithelial lining of the respiratory tract of freshly hatched chicks, predisposing them for respiratory infection. Alternatives for formaldehyde fumigation must be identified and …


Investigation Of Histomoniasis Prevention In Poultry, Lesleigh Beer Dec 2021

Investigation Of Histomoniasis Prevention In Poultry, Lesleigh Beer

Graduate Theses and Dissertations

Histomonas meleagridis is the etiological agent of histomoniasis, also commonly known as blackhead disease. This protozoal disease of poultry is detrimental to turkeys with flock mortalities often reaching 80-100%, although other gallinaceous birds are susceptible. Since the voluntary removal of nitarsone in 2015, the poultry industry is suffering with no approved prophylactics, therapeutics, or vaccines for this disease. The objectives of this dissertation were to evaluate multiple methods for prevention or control of histomoniasis, including dietary chemoprophylaxis and vaccination. Specifically, this research evaluated quinine as a chemoprophylactic candidate (Chapter 3) or live-attenuated H. meleagridis as vaccine candidates (Chapter 4) in …


Site-Specific Effects Of Lysine Acetylation On Aminoacyl-Trna Synthetase, Hao Chen Dec 2021

Site-Specific Effects Of Lysine Acetylation On Aminoacyl-Trna Synthetase, Hao Chen

Graduate Theses and Dissertations

Aminoacyl-tRNA synthetases (AARSs) are an ancient and highly conserved family of enzymes which can catalyze a two-steps aminoacylation reaction to charge tRNAs with their cognate amino acids, thus playing crucial roles in ribosomal protein synthesis. Naturally, the accurate amino acids and tRNA recognition of these synthetases are essential to the fidelity of translation process. To assure the correct recognition, some of these synthetases have evolved with an editing function to help remove the mischarged tRNAs. In addition to these functions, AARSs are also involved in various biological processes ranging from transcription to translation. Currently, a series of proteomic studies have …


A Case Study Of Eastern Region Arkansas Promise Participants And Their Expectations For The Future, Robin Freeman Dec 2021

A Case Study Of Eastern Region Arkansas Promise Participants And Their Expectations For The Future, Robin Freeman

Graduate Theses and Dissertations

The purpose of this study was to develop an in-depth understanding of how Eastern Arkansas youth with disabilities and their parents describe their expectations for the future, after participating in the Arkansas PROMISE program. The study sought an understanding of how participants viewed themselves and their expectations for the future, for employment, for participation in higher education, for independent living, and for future financial support. The research used a case study approach, interviewing five students and five parent participants. Participants were asked a series of questions to get an understanding of their experiences, their expectations for the future, and their …


Baseline Studies On Sex-Disaggregated Statistics Of Members And Gender Roles Of Officers Among Recognized Uplb Student Organizations, Jickerson P. Lado, Marcelina C. Miranda, Katrina Joy M. Abriol-Santos, Charlotte H. Hagosojos, Jimby E. Casquete, Marites E. Mojica, Nina M. Cadiz Dec 2021

Baseline Studies On Sex-Disaggregated Statistics Of Members And Gender Roles Of Officers Among Recognized Uplb Student Organizations, Jickerson P. Lado, Marcelina C. Miranda, Katrina Joy M. Abriol-Santos, Charlotte H. Hagosojos, Jimby E. Casquete, Marites E. Mojica, Nina M. Cadiz

Journal Article

The sex disaggregated statistics of members of recognized UPLB students organizations for five academic years were determined. Furthermore, the prevailing gender roles in elected key positions were identified. This is the first attempt to create and profile reorganized UPLB student organizations in terms of sex-disaggregated data (SDD) that could translate to effective policies and campaign strategies to enable a harmonized and gender-sensitive culture in UPLB. It sought to identify the assess the SDD of members among recognized UPLB student organization using both qualitative and quantitative methods of analysis. In a preliminary study, the data submitted by an average of 170 …


Rediscovering A Legacy Of A Lost Voice: A History Of Radyo Dzlb's School-On-The-Air, Mark Lester M. Chico Dec 2021

Rediscovering A Legacy Of A Lost Voice: A History Of Radyo Dzlb's School-On-The-Air, Mark Lester M. Chico

Journal Article

The school-on-the-air (SOA) is a pioneering broadcast program developed by Radyo DZLB in the University of the Philippines Los Baños, Laguna, Philippines. Its history dates back to 1967 when the first SOA and dairy farming was launched. Over the years, SOAs were redesigned until a formal structure was arrived at. Radyo DZLB faced challenges that compelled SOA continuously find its rightful place in the airwaves. Now that it is off the air, how can Radyo DZLB sustain its advocacy of educating farmers, homemakers, and children, among others, through SOA? As the voice development, how can Radyo DZLB recover its lost …


Management Strategies For Improving Survival Of Piglets From Hyperprolific Sows, R.N. Kirkwood, P. Langendijk, J. Carr Dec 2021

Management Strategies For Improving Survival Of Piglets From Hyperprolific Sows, R.N. Kirkwood, P. Langendijk, J. Carr

The Thai Journal of Veterinary Medicine

In efforts to improve profitability, sows have been subject to ongoing selection for larger litters. The current dogma is that larger litters improve sow productivity. This review, however, will question the validity of this assumption. It is inescapable that very large litters will have longer farrowing durations, lower average and more variable birth weights, and the sows will have insufficient teats available to feed their piglets. This is a recipe for increased piglet mortality with associated ethical considerations. This review will examine methods employed to address these challenges posed by larger litters in order to improve piglet survival. Producers, however, …


The Emergence Of A Texas Collaboration To Improve Well-Being In Learning Health Systems, Toi B Harris, Anil Nanda, Lilit A Sargsyan, Wei-Jung A Chen, Jennifer G Christner Dec 2021

The Emergence Of A Texas Collaboration To Improve Well-Being In Learning Health Systems, Toi B Harris, Anil Nanda, Lilit A Sargsyan, Wei-Jung A Chen, Jennifer G Christner

Faculty, Staff and Students Publications

Prior models of well-being have focused on resolving issues at different levels within a single institution. Changes over time in medicine have resulted in massive turnover and reduced clinical hours that portray a deficit-oriented system. As developments to improve purpose and professional satisfaction emerge, the Texas Medical Association Committee on Physician Health and Wellness (PHW) is committed to providing the vehicle for a statewide collaboration and illuminating the path forward.To describe the existing health and wellness resources in Texas academic medical centers and understand the gaps in resources and strategies for addressing the health and wellness needs in the medical …


Interaction Between Alcohol Consumption And Pnpla3 Variant In The Prevalence Of Hepatic Steatosis In The Us Population, Mariana Lazo, Usama Bilal, Mack C Mitchell, James Potter, Ruben Hernaez, Jeanne M Clark Dec 2021

Interaction Between Alcohol Consumption And Pnpla3 Variant In The Prevalence Of Hepatic Steatosis In The Us Population, Mariana Lazo, Usama Bilal, Mack C Mitchell, James Potter, Ruben Hernaez, Jeanne M Clark

Faculty, Staff and Students Publications

BACKGROUND & AIMS: To our knowledge, the interaction between alcohol consumption and PNPLA3 genotype on hepatic steatosis has not been explored in a representative sample. To examine the interaction between alcohol consumption and PNPLA3 genotype on hepatic steatosis in the US adult population.

METHODS: Cross-sectional study of 4,674 adult participants of the Third National Health and Nutrition Examination Survey, Phase 2 (1991-1994) with data on PNPLA3 genotype, self-reported alcohol consumption, ultrasound-defined hepatic steatosis and socio-demographic characteristics.

RESULTS: In 1991-1994 in the U.S. population, the weighted allele frequency of the G (risk) allele of the rs738409 at PNPLA3 was 25.4%. We …


Investigating The Relations Between Caffeine-Derived Metabolites And Plasma Lipids In 2 Population-Based Studies, Dusan Petrovic, Menno Pruijm, Belén Ponte, Nasser A. Dhayat, Daniel Ackermann, Georg Ehret, Nicolas Ansermot, Bruno Vogt, Pierre-Yves Martin, Jesus D. Melgarejo Dec 2021

Investigating The Relations Between Caffeine-Derived Metabolites And Plasma Lipids In 2 Population-Based Studies, Dusan Petrovic, Menno Pruijm, Belén Ponte, Nasser A. Dhayat, Daniel Ackermann, Georg Ehret, Nicolas Ansermot, Bruno Vogt, Pierre-Yves Martin, Jesus D. Melgarejo

School of Medicine Publications

Objective: To investigate the relations between caffeine-derived metabolites (methylxanthines) and plasma lipids by use of population-based data from 2 European countries.

Methods: Families were randomly selected from the general population of northern Belgium (FLEMENGHO), from August 12, 1985, until November 22, 1990, and 3 Swiss cities (SKIPOGH), from November 25, 2009, through April 4, 2013. We measured plasma concentrations (FLEMENGHO, SKIPOGH) and 24-hour urinary excretions (SKIPOGH) of 4 methylxanthines-caffeine, paraxanthine, theobromine, and theophylline-using ultra-high-performance liquid chromatography-tandem mass spectrometry. We used enzymatic methods to estimate total cholesterol, high-density lipoprotein cholesterol, and triglyceride levels and the Friedewald equation for low-density lipoprotein cholesterol …


The Landscape Of Renal Replacement Therapy In Veterans Affairs Medical Center Intensive Care Units, Chandan Vangala, Maulin Shah, Natasha N Dave, Layth Al Attar, Sankar D Navaneethan, Venkat Ramanathan, Susan Crowley, Wolfgang C Winkelmayer Dec 2021

The Landscape Of Renal Replacement Therapy In Veterans Affairs Medical Center Intensive Care Units, Chandan Vangala, Maulin Shah, Natasha N Dave, Layth Al Attar, Sankar D Navaneethan, Venkat Ramanathan, Susan Crowley, Wolfgang C Winkelmayer

Faculty, Staff and Students Publications

BACKGROUND: Outpatient dialysis is standardized with several evidence-based measures of adequacy and quality that providers aim to meet while providing treatment. By contrast, in the intensive care unit (ICU) there are different types of prolonged and continuous renal replacement therapies (PIRRT and CRRT, respectively) with varied strategies for addressing patient care and a dearth of nationally accepted quality parameters. To eventually describe appropriate quality measures for ICU-related renal replacement therapy (RRT), we first aimed to capture the variety and prevalence of basic strategies and equipment utilized in the ICUs of Veteran Affairs (VA) medical facilities with inpatient hemodialysis capabilities.

METHODS: …


Prevalence And Predictors Of Cost-Related Medication Nonadherence In Individuals With Cardiovascular Disease: Results From The Behavioral Risk Factor Surveillance System (Brfss) Survey, Riyad Kherallah, Mahmoud Al Rifai, Ishan Kamat, Chayakrit Krittanawong, Dhruv Mahtta, Michelle T Lee, Jing Liu, Khurram Nasir, Javier Valero-Elizondo, Jaideep Patel, Mouaz H Al-Mallah, Laura A Petersen, Salim S Virani Dec 2021

Prevalence And Predictors Of Cost-Related Medication Nonadherence In Individuals With Cardiovascular Disease: Results From The Behavioral Risk Factor Surveillance System (Brfss) Survey, Riyad Kherallah, Mahmoud Al Rifai, Ishan Kamat, Chayakrit Krittanawong, Dhruv Mahtta, Michelle T Lee, Jing Liu, Khurram Nasir, Javier Valero-Elizondo, Jaideep Patel, Mouaz H Al-Mallah, Laura A Petersen, Salim S Virani

Faculty, Staff and Students Publications

Medication nonadherence is highly prevalent among patients with chronic cardiovascular disease. Poor adherence has been associated with increased morbidity and mortality. Medication cost is a major driver for medication nonadherence. Utilizing data from the 2016 to 2018 Behavioral Risk Factor Surveillance System (BRFSS) survey, we estimated the prevalence of cost-related medication nonadherence (CRMNA) among the overall population and among individuals who reported a history of diabetes, atherosclerotic cardiovascular disease (ASCVD), or hypertension. We then performed multivariable logistic regression to analyze sociodemographic factors associated with CRMNA. Our study population consisted of 142,577 individuals of whom 24% were older than 65 years, …