Digital Commons Network^™

How One Nyc Hospital Handled The Covid-19 Pandemic- The Chief Residents’ Perspective, Sunny Arora, Krystyna Bronchard, Michaela Murphy, Stephen J. Peterson

Marshall Journal of Medicine

No abstract provided.

2021 October 28 - Academic Council Agenda And Minutes, Academic Council, East Tennessee State University

Academic Council Agenda and Minutes

No abstract provided.

Screening Of Lactic Acid Bacteria Against Pseudomonas Aeruginosa And Preliminary Study On Its Mechanism, Li Jian-Zhou, Xiao Yao-Ting, Li Hong-Xiao, Chen Xiao-Hua, Li An-Ping

Food and Machinery

Objective: In this study, Pseudomonas aeruginosa （PA） was used as the indicator bacteria, and based on the quorum sensing system, the lactic acid bacteria （LAB） that antagonized the effect of PA were screened and the antagonistic mechanism was preliminarily discussed. Methods: The mechanism of LAB antagonizing PA was explored by the tests of Oxford Cup Method screening LAB to inhibit the growth of PA, AI-2 expression of LAB, biofilm formation ability of PA, pyocyanin expression and the AI-2 expression of PA with LAB sterile supernatants, and the analysis of Pearson correlation. Results: The results showed that Lactobacillus gasseri LGchen and …

Innovative Approach To Measure Effectiveness Of Handwashing Education In School-Age Children By Extension Educators, Katie Hoffman, Surine Greenway, Julie Buck, Grace Wittman, Jang Ho Kim

Journal of Human Sciences and Extension

University of Idaho Extension educators developed an innovative approach to analyze the effectiveness of handwashing lessons taught to school-age children. A protocol was designed to determine if there was a significant decrease in bacterial Colony Forming Units (CFUs) before and after implementing an educational handwashing lesson. The protocol allowed Extension educators with limited to no research experience to validate their handwashing lessons with scientific research. A 79% reduction in Mean CFU counts pre- and post-handwashing was found, excluding an outlier. The results support the effectiveness of Extension handwashing lessons using a novel quantitative approach

Pilot Development Of A Critical Food Safety Message Visual Communication Tool For Farmers’ Market Vendors, Lilly W. Jan, Shannon M. Coleman, Anirudh Naig

Journal of Human Sciences and Extension

Farmers’ markets are popular sources of fresh and ready-to-eat foods for consumers in the United States. However, research indicates that food safety practices of vendors and their employees serve as a concern for customers. This pilot study focused on assessing a visual-based, minimal-text educational tool that was disseminated to farmers’ market vendors and employees (n = 27) in Iowa. The tool was evaluated using a post-intervention survey of vendors’ and employees’ knowledge of food safety practices and their attitudes towards the educational tool. The results did not show a statistically significant increase in attitude and knowledge scores of farmers’ market …

The Cowl - V. 86 N. 7 - Oct 28, 2021

The Cowl

The Cowl - student newspaper of Providence College. Vol. 86 No. 7 - October 28, 2021. 24 pages.

Prevalence And Multidrug Resistance Pattern Of E. Coli Among Urinary Tract Infection Patients In Tertiary Care Hospital Of Multan, Hubza Ruatt Khan, Mehvish Javeed, Asghar Javed, Nisma Farooq

Journal of Bioresource Management

Urinary Tract Infection is alarming problem worldwide due to the intensity of antimicrobial resistance. Escherichia coli is the most predominant organism in UTI. This study was planned to evaluate demographic parameters, the prevalence of E. coli, and antimicrobial resistance patterns among E. coli isolates from UTI patients in Nishtar Hospital of Multan from January to June 2018. A total of 350 mid-stream urine samples were collected from different patients having age group from 25 to 60 years and processed by standard laboratory procedures. Out of 350 samples, 100 samples were observed as critical bacteremia. Escherichia coli and Klebsiella …

Using 4-H Animal Science Programming To Improve One Health, Lacie Ashby, April Barczewski, Ashley Travis, Chris Anderson, Sheryl Bennett

Journal of Human Sciences and Extension

Zoonoses, or diseases that can be transferred between humans and animals, such as variant swine influenza, avian influenza A viruses, and coronaviruses, comprise a large percentage of all newly identified and existing infectious diseases (Centers for Disease Control and Prevention, 2017). As a result, there is an ever-growing need for a One Health approach towards preventing and controlling zoonotic diseases. To better manage these public health risks at the human-animal-environment interface, Maryland 4-H and Maryland Department of Health initiated a statewide, multi-agency collaborative partnership. Through steps taken to collectively develop and implement long-term strategies to prevent future variant influenza outbreaks …

Seasonality In Competence To Transmit West Nile Virus For A Widespread Reservoir, Kyle L. Koller

USF Tampa Graduate Theses and Dissertations

All organisms face a central conflict; a limited supply of resources must beoptimally allocated to competing biological functions. Utilizing robust immune defenses can be energetically costly;, thus, immune function is often diminished when other processes, such as reproduction, molt, or migration demand energy. As wild animals residing in temporally dynamic environments face seasonal patterns in resource availability, infectious disease risk, and environmental suitability, many species have evolved endogenous biological rhythms so that the performance of reproduction, molt, or migration and the associated trade-off with immune function be completed when doing so best promotes fitness. In turn, this demand to optimize …

October 28, 2021, James Madison University

The Breeze, 2020-

The Breeze is the student newspaper of James Madison University in Harrisonburg, Virginia.

Biological Characterization Of Plasmodium Falciparum Mitochondrial Heat Shock Protein Pfhsp70-3: Possible Involvement In Malaria Pathogenesis, David O. Nyakundi, Aileen Boshoff

Tanzania Journal of Science

Malaria remains a global health burden accounting for many deaths and illnesses in sub-Saharan Africa notwithstanding many decades of research on the disease. P. falciparum, the causative agent of the most fatal form of malaria, expresses a repertoire of heat shock proteins (Hsp) that cushion the parasite against heat shocks as it shuttles between extreme temperatures in human and mosquito vector hosts. By so doing, such proteins promote parasite’s cytoprotection, survival and pathogenesis. Heat shock proteins are named according to their molecular weights and there are six P. falciparum Hsp70 (PfHsp70) found in various cell compartments with mitochondrial putative PfHsp70-3. …

A Mathematical Analysis Of An In-Vivo Ebola Virus Transmission Dynamics Model, Seleman Ismail, Adeline Peter Mtunya

Tanzania Journal of Science

Ebola virus (EBOV) infection is a hemorrhagic and hazardous disease, which is among the most shocking threats to human health causing a large number of deaths. Currently, there are no approved curative therapies for the disease. In this study, a mathematical model for in-vivo Ebola virus transmission dynamics was analyzed. The analysis of the model mainly focused on the sensitivity of basic reproductive number,  pertaining to the model parameters. Particularly, the sensitivity indices of all parameters of  were computed by using the forward normalized sensitivity index method. The results showed that a slight change in the infection rate immensely influences …

The Impact Of Outpatient Laboratory Alerting Mechanisms In Patients With Aki, Nicole V Tolan, Salman Ahmed, Tolumofe Terebo, Zain M Virk, Athena K Petrides, Jaime R Ransohoff, Christiana A Demetriou, Yvelynne P Kelly, Stacy E F Melanson, Mallika L Mendu

Faculty, Staff and Students Publications

BACKGROUND: AKI is an abrupt decrease in kidney function associated with significant morbidity and mortality. Electronic notifications of AKI have been utilized in patients who are hospitalized, but their efficacy in the outpatient setting is unclear.

METHODS: We evaluated the effect of two outpatient interventions: an automated comment on increasing creatinine results (intervention I; 6 months;

RESULTS: Providers were more likely to document AKI in interventions I (

CONCLUSIONS: An automated comment was associated with improved documented recognition of AKI and the additive intervention of an email alert was associated with increased discontinuation of nephrotoxins, but neither improved clinical outcomes. …

Saving The Nonessential With Radical Tax Policy, Rodney P. Mock, Kathryn Kisska-Schulze

University of Cincinnati Law Review

Under the Internal Revenue Code of 1986, as amended, for-profit entities are distinguishable from tax-exempt entities in that they, among other factors, pursue profits, and enjoy unrestricted commercial activities. The COVID-19 lockdowns prevented commercial activity for numerous for-profit small businesses. For the first time in United States history, a distinction was made between "essential" and "nonessential" businesses. Such distinction is historically absent in both legal scholarship and tax law; instead, it is a product of governmental reaction to the COVID-19 pandemic. Via executive order, nonessential businesses were characterized as being trivial to the fabric of society, and thus shuttered, while …

When The Conditions Are The Confinement: Eighth Amendment Habeas Claims During Covid-19, Michael L. Zuckerman

University of Cincinnati Law Review

The COVID-19 pandemic cast into harsher relief much that was already true about mass incarceration in the United States. It also cast into harsher relief much that was already true about the legal barriers confronting people seeking to make its conditions more humane. This Article offers a brief overview of the legal landscape as the COVID-19 crisis arose and then surveys eight prominent federal cases involving Eighth Amendment claims related to COVID-19 outbreaks at carceral facilities, most of which included significant litigation over whether they could secure release through habeas corpus. The Article then distills six key tensions from these …

Racial And Ethnic Data Reported For Peanut Allergy Epidemiology Do Little To Advance Its Cause, Treatment, Or Prevention, Nigel Mark Thomas

Publications and Research

No abstract provided.

Twenty Years After The Anthrax Terrorist Attacks Of 2001: Lessons Learned And Unlearned For The Covid-19 Response, Lawrence O. Gostin, Jennifer B. Nuzzo

Georgetown Law Faculty Publications and Other Works

The 20th anniversary of the terrorist attacks on September 11, 2001, resulted in deep national reflection. Less remembered are the events that began to unfold 7 days later as anonymous letters laced with deadly anthrax (Bacillus anthracis) spores began arriving at postal facilities, media companies, and congressional offices. The first death from inhaled anthrax exposure occurred on October 5, with an additional 4 deaths and 17 infections over the ensuing months.

The anthrax attacks exposed a health system ill-equipped to respond to acute emergencies. This article explores the lessons learned, and unlearned, from the anthrax attacks, through to …

Spectrum, Volume 47, Issue 6, Sacred Heart University

Newspapers (Obelisk & Spectrum)

Highlights include: Dead's at Red's -- Plans for Halloween -- SHU Alumnus Dario Melendez -- New Netflix Series "Squid Games" -- Trick-or-Treat for UNICEF Fundraiser -- "Legends of Fear" Haunted House -- Spotlight: The s.w.e.e.t Life of Therapy Animals -- Arts and Entertainment -- Football Grabs Win over CCSU -- Sacred Heart Men’s Hockey Upsets #12 Boston University-- Women’s Bowling Looks to Roll over Competition This Season

High Seropositivity Rate Of Neutralizing Antibodies To Astrovirus Va1 In Human Populations, Andrew B Janowski, Macee C Owen, Holly Dudley, Tomás López, Rafaela Espinosa, Memory Elvin-Lewis, Alejandro Colichon, Carlos F Arias, Peter D Burbelo, David Wang

Open Access Publications

Astroviruses are common pathogens of the human gastrointestinal tract, but they have been recently identified from cases of fatal meningoencephalitis. Astrovirus VA1 is the most frequently detected astrovirus genotype from cases of human encephalitis, but the prevalence of neutralizing antibodies to VA1 in human sera is unknown. We developed a focus reduction neutralization assay (FRNT) for VA1 and measured the seroprevalence of neutralizing antibodies from two cohorts of adult and pediatric serum samples: (i) an age-stratified cohort from St. Louis, MO, collected from 2007 to 2008 and (ii) a cohort from the Peruvian Amazonian River Basin collected in the late …

Collections Education: The Extended Specimen And Data Acumen, Anna K. Monfils, Erica R. Krimmel, Debra L. Linton, Travis D. Marsico, Ashley B. Morris, Brad R. Ruhfel

Open Access Fund Publications

Biodiversity scientists must be fluent across disciplines; they must possess the quantitative, computational, and data skills necessary for working with large, complex data sets, and they must have foundational skills and content knowledge from ecology, evolution, taxonomy, and systematics. To effectively train the emerging workforce, we must teach science as we conduct science and embrace emerging concepts of data acumen alongside the knowledge, tools, and techniques foundational to organismal biology. We present an open education resource that updates the traditional plant collection exercise to incorporate best practices in twenty-first century collecting and to contextualize the activities that build data acumen. …

2021-10-26_Michiganoverview_Covidsymptoms, Michigan Department Of Health & Human Services

Michigan COVID-19 Syndromic Surveillance System Data

The Syndromic Surveillance System Data report was obtained from Michigan's COVID-19 dashboard, from under the link "​Coronavirus Symptoms": https://www.michigan.gov/coronavirus. Data was compiled by the Michigan Department of Health and Human Services (MDHHS). The information was updated three times a week on Mondays, Wednesdays and Fridays.

Syndromic Surveillance System data is obtained from approximately 216 facilities participating in syndromic surveillance (139 Emergency Departments (ED), 77 Urgent Care) across the State of Michigan. The reporting is based on individuals who present at EDs and may not be representative of the overall population. The coronavirus-like symptoms query searches visit free-text (chief complaint, …

Covid-19 Newsletter (Vol. 92), Center For Disaster Medicine, New York Medical College

COVID-19 Newsletter

No abstract provided.

Case Series: Demonstration Of The Criticality Of Early Identification For Vestibular Labyrinthitis, Taylor Schaul, Antony Joseph

AuD Capstone Projects - Communication Sciences and Disorders

Introduction: labyrinthitis occurs when both branches of the vestibulocochlear nerve swell, specifically the vestibular and cochlear portions. Diagnosed by the process of elimination, labyrinthitis can have detrimental auditory and vestibular effects when identified untimely. When diagnosed early, labyrinthitis can be resolved with rest, medication, and vestibular rehabilitation therapy. Case Presentation: A young adult presented to the clinic with a heavy head sensation, lack of concentration, and blurry vision that escalated to left ear fullness, unilateral tinnitus, and an untriggered persistent headache. Discussion: This patient was undiagnosed for three months due to the unavailability of vestibular testing in the emergency room …

A Novel Class Of Tmprss2 Inhibitors Potently Block Sars-Cov-2 And Mers-Cov Viral Entry And Protect Human Epithelial Lung Cells, Matthew Mahoney, Vishnu C Damalanka, Michael A Tartell, Anne E Mayer Bridwell, Jorine Voss, Partha Karmakar, Paul W Rothlauf, Cassandra E Thompson, Christina L Stallings, Sean P J Whelan, James W Janetka, Et Al

Open Access Publications

The host cell serine protease TMPRSS2 is an attractive therapeutic target for COVID-19 drug discovery. This protease activates the Spike protein of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and of other coronaviruses and is essential for viral spread in the lung. Utilizing rational structure-based drug design (SBDD) coupled to substrate specificity screening of TMPRSS2, we have discovered covalent small-molecule ketobenzothiazole (kbt) TMPRSS2 inhibitors which are structurally distinct from and have significantly improved activity over the existing known inhibitors Camostat and Nafamostat. Lead compound MM3122 (4) has an IC

The Compounding Effect Of Rurality On Health Disparities Among Black Patients With Covid-19, Jessica E. Johnson, Ruchi Bhandari, Allison Lastinger, Rebecca Reece

Journal of Appalachian Health

Background: West Virginia had garnered national attention for its vaccination rollout against coronavirus 2019 (COVID-19). Outcomes of this mostly rural population, however, have been underreported. As the pandemic continues, identifying high risk populations remains important to further epidemiologic information and target vaccines.

Purpose: The objective of this study is to examine the effects of COVID-19 and the influence of race and rurality on hospitalization and outcomes in Appalachians.

Methods: In this retrospective study, data from patients who tested positive and were admitted for COVID-19 and seen within the state’s largest health system (West Virginia University Health System) between March …

The Importance Of Time, Place, And Person: Applying Elementary Epidemiology To Covid-19 Outcomes In Rural Appalachia, Linda Alexander, F. Douglas Scutchfield Md

Journal of Appalachian Health

Since the 1800s this traditional triad of descriptive epidemiology has allowed for effective interventions to deal with epidemics. A focus on time, place, and person also provides a critical framework for interventions in controlling the epidemic by focusing on those populations with the highest risk for disease.

Crisis Induced Innovation In U.S. Legal Education, Morenike Saula

Journal of Legal Education

No abstract provided.

A Retrospective Case Study Of Successful Translational Research: Gazelle Hb Variant Point-Of-Care Diagnostic Device For Sickle Cell Disease, Kelli Qua, Shannon M. Swiatkowski, Umut A. Gurkan, Clara M. Pelfrey

Faculty Scholarship

Evaluation researchers at Clinical and Translational Science Award (CTSA) hubs are conducting retrospective case studies to evaluate the translational research process. The objective of this study was to deepen knowledge of the translational process and identify contributors to successful translation. We investigated the successful translation of the HemeChip, a low-cost point-of-care diagnostic device for sickle cell disease, using a protocol for retrospective translational science case studies of health interventions developed by evaluators at the National Health Institutes (NIH) and CTSA hubs. Development of the HemeChip began in 2013 and evidence of device use and impact on public health is growing. …

The Rider (2021-10-25), Verilu Infante

The Rider Archives

Vol.7 No.10

Discovering Disease-Disease Associations Using Electronic Health Records In The Guideline Advantage (Tga) Dataset, Aixia Guo, Yosef M Khan, James R Langabeer 2nd, Randi E Foraker

Open Access Publications

Certain diseases have strong comorbidity and co-occurrence with others. Understanding disease-disease associations can potentially increase awareness among healthcare providers of co-occurring conditions and facilitate earlier diagnosis, prevention and treatment of patients. In this study, we utilized the valuable and large The Guideline Advantage (TGA) longitudinal electronic health record dataset from 70 outpatient clinics across the United States to investigate potential disease-disease associations. Specifically, the most prevalent 50 disease diagnoses were manually identified from 165,732 unique patients. To investigate the co-occurrence or dependency associations among the 50 diseases, the categorical disease terms were first mapped into numerical vectors based on disease …