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2021

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Bactericidal Effects And Stability Of Ll-37 And Cama In The Presence Of Human Lung Epithelial Cells, Regina Geitani, Carole Ayoub Moubareck, Floriane Costes, Léa Marti, Gabrielle Dupuis, Dolla Karam Sarkis, Lhousseine Touqui Dec 2021

Bactericidal Effects And Stability Of Ll-37 And Cama In The Presence Of Human Lung Epithelial Cells, Regina Geitani, Carole Ayoub Moubareck, Floriane Costes, Léa Marti, Gabrielle Dupuis, Dolla Karam Sarkis, Lhousseine Touqui

All Works

Cationic antimicrobial peptides (CAMPs) are important actors in host innate immunity and represent a promising alternative to combat antibiotic resistance. Here, the bactericidal activity of two CAMPs (LL-37, and CAMA) was evaluated against Pseudomonas aeruginosa (PA) in the presence of IB3-1 cells, a cell line derived from patients with cystic fibrosis. The two CAMPs exerted different effects on PA survival depending on the timing of their administration. We observed a greater bactericidal effect when IB3-1 cells were pretreated with sub-minimum bactericidal concentrations (Sub-MBCs) of the CAMPs prior to infection. These findings suggest that CAMPs induce the production of factors by …


Atrial Fibrillation In Middle Eastern Arabs And South Asians: A Scoping Review, Amar M. Salam, Rasha Kaddoura, Vehid Salih, Sanjay Asopa Dec 2021

Atrial Fibrillation In Middle Eastern Arabs And South Asians: A Scoping Review, Amar M. Salam, Rasha Kaddoura, Vehid Salih, Sanjay Asopa

Peninsula Dental School

No abstract provided.


Announcements For Japas 9(2), Japas Editors Dec 2021

Announcements For Japas 9(2), Japas Editors

Journal of Amish and Plain Anabaptist Studies

No abstract provided.


Positive Leadership Theory For Online Dissertation Mentoring, Lee Stadtlander Dec 2021

Positive Leadership Theory For Online Dissertation Mentoring, Lee Stadtlander

Journal of Educational Research and Practice

A number of theoretical models have been suggested for how to mentor doctoral students. However, they tend to rely on hierarchical and authoritarian relationships between the faculty and students. Such models tend to create dependency and fear of the faculty, resulting in a reluctance in coming to the mentor for guidance. Such models do not tend to work well with online adult doctoral students with jobs and families. This paper proposes a model of positive leadership for online doctoral mentors, where mentors are accessible and create an environment where success is assumed and social support is provided by both the …


Agricultural Support For The Old Colony Mennonites Of Belize: A Collaborative Effort Between North American Old Order Mennonites And A Cornell Extension Educator, Judson Reid Dec 2021

Agricultural Support For The Old Colony Mennonites Of Belize: A Collaborative Effort Between North American Old Order Mennonites And A Cornell Extension Educator, Judson Reid

Journal of Amish and Plain Anabaptist Studies

The Old Colony Mennonites of Belize practice a conservative form of Anabaptism where technology, dress and lifestyle choices are informed by church standards. Members live in a spatially contiguous Colony, which creates land pressure over time as population increases. The development of new Colonies is necessary for the Mennonites to participate in agricultural livelihoods. The Indian Creek Colony of Belize has experienced agricultural and economic hardships since its inception in the 1989 due to land costs, crop failures and debt structure. Old Order Mennonites of North America developed an outreach effort to assist with on-farm production of vegetable crops to …


Penn State Extension Services And Plain People: An Inside Perspective On A Trust-Based Relationship, Phillip Martin Dec 2021

Penn State Extension Services And Plain People: An Inside Perspective On A Trust-Based Relationship, Phillip Martin

Journal of Amish and Plain Anabaptist Studies

This perspective on Penn State Extension Services and plain people is based on my personal experiences as a plain person, in which I interacted with Extension Services first as a farmer, and then (while working on a doctorate) as a part of the Extension system. Penn State Extension started over a century ago and was deliberate in reaching out to plain (conservative Anabaptist) farmers since the beginning, which led to a history of trust-based cooperation. For all these successes there remain challenges to effective cooperation with certain plain individuals and subgroups. I suggest these challenges are broadly similar to those …


Hotline Number To Reach And Offer Agricultural Information To Plain Anabaptists During The Covid-19 Workplace Closures, Emily Shoop, Carly Becker, Nathan Glenn Briggs, Danielle Smarsh Dec 2021

Hotline Number To Reach And Offer Agricultural Information To Plain Anabaptists During The Covid-19 Workplace Closures, Emily Shoop, Carly Becker, Nathan Glenn Briggs, Danielle Smarsh

Journal of Amish and Plain Anabaptist Studies

The Penn State Extension Animal Systems Team developed a toll-free hotline phone number to convey short educational messages to maintain contact and outreach to Pennsylvania’s animal producing Amish, Mennonite, and other plain Anabaptist populations. During the COVID-19 pandemic, Penn State Extension’s programming went largely online via webinars, online courses, and emails. This change in programming excluded a large sector of Pennsylvania farmers who do not use or have access to the internet and, as such, were liable to miss important best management practice reviews and timely updates in animal agriculture. The Animal Systems Hotline offered callers the choice to listen …


Providing Agricultural Information To Amish And Mennonite Farmers: Creative Adaptations To Wisconsin Extension Programs And Communications, Richard Halopka Dec 2021

Providing Agricultural Information To Amish And Mennonite Farmers: Creative Adaptations To Wisconsin Extension Programs And Communications, Richard Halopka

Journal of Amish and Plain Anabaptist Studies

This service provider report taps into the experience of a longtime Extension Educator in Wisconsin. Pulling from his work in Clark County, WI, where Amish and Old Order Mennonites have been particularly important to the local agricultural economy, he provides examples of how Extension can modify programming to meet the needs of plain producers. Topics of interest to Amish and Mennonite farmers include nutrient management, forage quality, and farm safety. Areas of program modification include approaches to communication, training, and support in ways that are culturally sensitive to church restrictions. In-person training and informational voicemail recordings have been particularly useful …


Effective Communication And Programming When Working With Amish Farmers: Reflections From A Wisconsin Agriculture Educator, Vance Haugen Dec 2021

Effective Communication And Programming When Working With Amish Farmers: Reflections From A Wisconsin Agriculture Educator, Vance Haugen

Journal of Amish and Plain Anabaptist Studies

The author, an agricultural educator who worked with the Amish in Wisconsin for over 30 years, discusses his outreach efforts, which have been focused on managed grazing, a method well suited to Amish producers. Managed grazing offers agronomic, economic, and ecological benefits. A key educational tool for communicating managed grazing practices is the pasture walk, and the author relates lessons learned from these events. The communal nature and focus on farmer-to-farmer information exchange is well received by Amish producers. It is helpful if pasture walk scheduling is done well in advance and is focused on farmer-based problems with farmer-based solutions …


The Success Of Plain People’S Produce Auctions And Partnership With Missouri Extension, James Quinn, John Kruse, Londa Nwadike, James C. Piñero, David Trinklein Dec 2021

The Success Of Plain People’S Produce Auctions And Partnership With Missouri Extension, James Quinn, John Kruse, Londa Nwadike, James C. Piñero, David Trinklein

Journal of Amish and Plain Anabaptist Studies

The number of produce auctions led by plain Anabaptist producers has surged since the mid-1990s. Typically grower-owned, these businesses are centralized facilities providing a wholesale market to area growers for a diverse group of buyers. For growers seeking an adequate living from growing produce, these facilities help reduce marketing time and product transportation, and provide frequent sales events that guarantee payment. As such, they have developed into a solid and long-standing market for local produce. However, plain growers have experienced challenges trying new crops or scaling up production. This article details how Missouri Extension assisted plain farmers with their challenges …


Farm Food Safety Training For Amish Produce Growers Covered Under The Food Safety Modernization Act (Fsma), Luke Laborde, Jeffrey Stoltzfus, Kaila Thorn Dec 2021

Farm Food Safety Training For Amish Produce Growers Covered Under The Food Safety Modernization Act (Fsma), Luke Laborde, Jeffrey Stoltzfus, Kaila Thorn

Journal of Amish and Plain Anabaptist Studies

Commercial production of fruits and vegetables on Amish farms provides significant amounts of fresh produce that are regionally distributed through wholesale markets. In response to several multi-state foodborne disease outbreaks linked to contamination of fresh produce, the U.S. Food and Drug Administration (FDA) mandated farm food safety standards that most commercial produce growers must implement. Although there have been no foodborne disease outbreaks attributed to fresh produce grown on Amish farms, this regulation poses regulatory challenges for those who sell produce at wholesale produce auctions, cooperatives, and distribution warehouses. This article describes recent farm food safety standards issued by the …


Performing Amish Agrarianism: Negotiating Tradition In The Maintenance Of Pennsylvania Dairy Farms, Nicole Welk-Joerger Dec 2021

Performing Amish Agrarianism: Negotiating Tradition In The Maintenance Of Pennsylvania Dairy Farms, Nicole Welk-Joerger

Journal of Amish and Plain Anabaptist Studies

Amish people have a reputation for being ecologically and environmentally conscientious. As numerous scholars in Amish and Plain Anabaptist studies have demonstrated, Amish views of the environment are diverse and ultimately anchored in the understanding that God made nature for human use. In these cases, Amish views of the environment could be described as much more anchored in traditional philosophical notions of “agrarianism” than “environmentalism.” In this article, I explore how some Amish approach agrarianism with a turn from more traditional farm life toward necessary economic engagement with multi-faceted operations and diversification. Based on intensive ethnographic research and participant observation, …


Caring For The Land And The Livestock: Anabaptist Agricultural Practices In Europe And Colonial Pennsylvania, Rebecca Shenton Dec 2021

Caring For The Land And The Livestock: Anabaptist Agricultural Practices In Europe And Colonial Pennsylvania, Rebecca Shenton

Journal of Amish and Plain Anabaptist Studies

Anabaptists have a strong history of agricultural innovation and care for the land. Their innovative spirit was forged out of persecution, migration, and the need to survive in challenging circumstances. This article examines the agricultural practices of seventeenth- and eighteenth-century Swiss and South German Anabaptist farmers and those of eighteenth-century Anabaptist immigrants to Pennsylvania. European Anabaptist tenant farmers distinguished themselves by their family-centered mixed agriculture and their investment in both the land (using manure, lime, gypsum, and crop rotation to improve the soil) and livestock (improving natural meadows and planting pastures for fodder, maintaining clean barns, practicing confinement feeding, and …


Direct Foam Writing In Microgravity, Guy Jacob Cordonier, Cicely Sharafati, Spencer Mays, Lukas Thackery, Ellena Gemmen, Samuel Cyphert, Megan Brown, John Quinn Napolillo, Savannah Toney, Hunter Moore, John M. Kuhlman `, Konstantinos A. Sierros Dec 2021

Direct Foam Writing In Microgravity, Guy Jacob Cordonier, Cicely Sharafati, Spencer Mays, Lukas Thackery, Ellena Gemmen, Samuel Cyphert, Megan Brown, John Quinn Napolillo, Savannah Toney, Hunter Moore, John M. Kuhlman `, Konstantinos A. Sierros

Faculty & Staff Scholarship

Herein we report 2D printing in microgravity of aqueous-based foams containing metal oxide nanoparticles. Such hierarchical foams have potential space applications, for example for in situ habitat repair work, or for UV shielding. Foam line patterns of a TiO2-containing foam have been printed onto glass substrates via Direct Foam Writing (DFW) under microgravity conditions through a parabolic aircraft flight. Initial characterization of the foam properties (printed foam line width, bubble size, etc.) are presented. It has been found that gravity plays a significant role in the process of direct foam writing. The foam spread less over the substrate when deposited …


1955 - Jan. 6, Carolyn Brown Dodge Dec 2021

1955 - Jan. 6, Carolyn Brown Dodge

Carolyn Brown Dodge Letters

Carolyn Dodge resided in Ellensburg, Washington, in the Badger Pocket area on a farm with her family and her letters describe her daily life as a farm wife and later as the wife of a potato broker in the Quincy Basin. She also wrote letters to her cousin at her residences in Kittitas and Quincy, Washington, following her time in Ellensburg.


Forward Together Update [Winter Break Update], December 21, 2021, University Of Northern Iowa Dec 2021

Forward Together Update [Winter Break Update], December 21, 2021, University Of Northern Iowa

UNI Response to COVID-19

A winter break update on the importance of getting a booster shot, travel and holiday recommendations, Student Health Clinic hours, a reminder about the voluntary vaccine verification process, and the Panther Health Survey.


Induction Of Il19 Expression Through Jnk And Cgas-Sting Modulates Dna Damage–Induced Cytokine Production, Sara H. Small, E. Jessica Tang, Ryan L. Ragland, Yaroslava Ruzankina, David W. Schoppy, Rahul S. Mandal, M. Rebecca Glineburg, Zgjim Ustelenca, Daniel J. Powell, Fiona Simpkins, F. Bradley Johnson, Eric J. Brown Dec 2021

Induction Of Il19 Expression Through Jnk And Cgas-Sting Modulates Dna Damage–Induced Cytokine Production, Sara H. Small, E. Jessica Tang, Ryan L. Ragland, Yaroslava Ruzankina, David W. Schoppy, Rahul S. Mandal, M. Rebecca Glineburg, Zgjim Ustelenca, Daniel J. Powell, Fiona Simpkins, F. Bradley Johnson, Eric J. Brown

Biology, Chemistry, and Environmental Sciences Faculty Articles and Research

Cytokine production is a critical component of cell-extrinsic responses to DNA damage and cellular senescence. Here, we demonstrated that expression of the gene encoding interleukin-19 (IL-19) was enhanced by DNA damage through pathways mediated by c-Jun amino-terminal kinase (JNK) and cGAS-STING and that IL19 expression was required for the subsequent production of the cytokines IL-1, IL-6, and IL-8. IL19 expression was stimulated by diverse cellular stresses, including inhibition of the DNA replication checkpoint kinase ATR (ataxia telangiectasia and Rad3-related protein), oncogene expression, replicative exhaustion, oxidative stress, and DNA double-strand breaks. Unlike the production of IL-6 and IL-8, IL19 expression was …


Coronavirus Update 12-21-21, The Coronavirus Planning Team Dec 2021

Coronavirus Update 12-21-21, The Coronavirus Planning Team

University Briefings & Virtual Events

As we prepare for what appears to be a challenging January, we want to remind you of the need to receive a booster shot before your return to campus after the Christmas break if you are eligible or no later than March 1.


Usa V. Donte Taylor Dec 2021

Usa V. Donte Taylor

2021 Decisions

USDC for the Western District of Pennsylvania


An Examination Of Poverty: Dimensions, Causes, And Solutions, David Nii O. Tackie Dec 2021

An Examination Of Poverty: Dimensions, Causes, And Solutions, David Nii O. Tackie

Journal of Rural Social Sciences

This article, based on the 2021 Southern Rural Sociological Association (SRSA) Presidential Address, assesses the dimensions, causes of, and solutions to poverty. It finds that the definition of poverty varies based on the criteria used, and even by which agency or institution is defining it. It also finds that poverty indices vary by state and by county. For instance, in selected SRSA states, Virginia has the lowest poverty rate and Mississippi has the highest poverty rate. There are several causes of poverty, some of which are lower levels of education, lower levels of health, unemployment, lack of livable wages, and …


Assessment Of Virus-Induced Myocarditis In Human Heart Tissue Samples, Gabriel Galeotos Dec 2021

Assessment Of Virus-Induced Myocarditis In Human Heart Tissue Samples, Gabriel Galeotos

Honors Theses

The heart is a major organ whose function is to transport nutrients and waste throughout the body. This organ can become infected by pathogens, such as viruses, bacteria, or parasites. Infection of the middle heart layer, or myocardium, is often caused by a viral agent. This disease has three stages: viral infiltration, adaptive immune system activation, and finally either viral clearance or cardiac cell remodeling. During this process the immune system will begin to secrete cytokines, which are signaling molecules that alert other members of the immune pathways, and also participate in cardiac remodeling. Evaluating the correlation between the cytokine …


Michelle Mcdonald-Witherspoon V. City Of Philadelphia Dec 2021

Michelle Mcdonald-Witherspoon V. City Of Philadelphia

2021 Decisions

USDC for the Eastern District of Pennsylvania


Kenth Rogers V. Director Internal Revenue Bure Dec 2021

Kenth Rogers V. Director Internal Revenue Bure

2021 Decisions

USDC for the District Court of the Virgin Islands


Durable Nanocomposite Face Masks With High Particulate Filtration And Rapid Inactivation Of Coronaviruses, Andrew Gonzalez, Hamada A. Aboubakr, John Brockgreitens, Weixing Hao, Yang Wang, Sagar M. Goyal, Abdennour Abbas Dec 2021

Durable Nanocomposite Face Masks With High Particulate Filtration And Rapid Inactivation Of Coronaviruses, Andrew Gonzalez, Hamada A. Aboubakr, John Brockgreitens, Weixing Hao, Yang Wang, Sagar M. Goyal, Abdennour Abbas

Civil, Architectural and Environmental Engineering Faculty Research & Creative Works

The COVID-19 pandemic presents a unique challenge to the healthcare community due to the high infectivity rate and need for effective personal protective equipment. Zinc oxide nanoparticles have shown promising antimicrobial properties and are recognized as a safe additive in many food and cosmetic products. This work presents a novel nanocomposite synthesis approach, which allows zinc oxide nanoparticles to be grown within textile and face mask materials, including melt-blown polypropylene and nylon-cotton. The resulting nanocomposite achieves greater than 3 log10 reduction (≥ 99.9%) in coronavirus titer within a contact time of 10 min, by disintegrating the viral envelope. The …


Ronan Carroll Receives Rakowski Award Continues Research Into Genetics Of Staphylococcal Infections, Ohio University College Of Arts & Sciences Dec 2021

Ronan Carroll Receives Rakowski Award Continues Research Into Genetics Of Staphylococcal Infections, Ohio University College Of Arts & Sciences

All Forum Articles

No abstract provided.


Trauma Exposures, Resilience Factors, And Mental Health Outcomes In Persons Granted Asylum In The U.S. For Claims Related To Domestic Violence And Persecution By Organized Gangs., Eleanor H Emery, Mehar Maju, Kate Coursey, Cameron Brandt, Jamie S Ko, Kathryn Hampton, Adam Richards Dec 2021

Trauma Exposures, Resilience Factors, And Mental Health Outcomes In Persons Granted Asylum In The U.S. For Claims Related To Domestic Violence And Persecution By Organized Gangs., Eleanor H Emery, Mehar Maju, Kate Coursey, Cameron Brandt, Jamie S Ko, Kathryn Hampton, Adam Richards

Global Health Faculty Publications

No abstract provided.


Genetic Contributors Of Incident Stroke In 10,700 African Americans With Hypertension: A Meta-Analysis From The Genetics Of Hypertension Associated Treatments And Reasons For Geographic And Racial Differences In Stroke Studies, Nicole D. Armstrong, Vinodh Srinivasasainagendra, Amit Patki, Rikki M. Tanner, Bertha A. Hidalgo, Hemant K. Tiwari, Nita A. Limdi, Ethan M. Lange, Leslie A. Lange, Donna K. Arnett, Marguerite R. Irvin Dec 2021

Genetic Contributors Of Incident Stroke In 10,700 African Americans With Hypertension: A Meta-Analysis From The Genetics Of Hypertension Associated Treatments And Reasons For Geographic And Racial Differences In Stroke Studies, Nicole D. Armstrong, Vinodh Srinivasasainagendra, Amit Patki, Rikki M. Tanner, Bertha A. Hidalgo, Hemant K. Tiwari, Nita A. Limdi, Ethan M. Lange, Leslie A. Lange, Donna K. Arnett, Marguerite R. Irvin

Epidemiology and Environmental Health Faculty Publications

Background: African Americans (AAs) suffer a higher stroke burden due to hypertension. Identifying genetic contributors to stroke among AAs with hypertension is critical to understanding the genetic basis of the disease, as well as detecting at-risk individuals.

Methods: In a population comprising over 10,700 AAs treated for hypertension from the Genetics of Hypertension Associated Treatments (GenHAT) and Reasons for Geographic and Racial Differences in Stroke (REGARDS) studies, we performed an inverse variance-weighted meta-analysis of incident stroke. Additionally, we tested the predictive accuracy of a polygenic risk score (PRS) derived from a European ancestral population in both GenHAT and REGARDS AAs …


1954 - Mar. 28, Carolyn Brown Dodge Dec 2021

1954 - Mar. 28, Carolyn Brown Dodge

Carolyn Brown Dodge Letters

Carolyn Dodge resided in Ellensburg, Washington, in the Badger Pocket area on a farm with her family and her letters describe her daily life as a farm wife and later as the wife of a potato broker in the Quincy Basin. She also wrote letters to her cousin at her residences in Kittitas and Quincy, Washington, following her time in Ellensburg.


1962 - May 9, Carolyn Brown Dodge Dec 2021

1962 - May 9, Carolyn Brown Dodge

Carolyn Brown Dodge Letters

Carolyn Dodge resided in Ellensburg, Washington, in the Badger Pocket area on a farm with her family and her letters describe her daily life as a farm wife and later as the wife of a potato broker in the Quincy Basin. She also wrote letters to her cousin at her residences in Kittitas and Quincy, Washington, following her time in Ellensburg.


1962 - Aug. 2, Carolyn Brown Dodge Dec 2021

1962 - Aug. 2, Carolyn Brown Dodge

Carolyn Brown Dodge Letters

Carolyn Dodge resided in Ellensburg, Washington, in the Badger Pocket area on a farm with her family and her letters describe her daily life as a farm wife and later as the wife of a potato broker in the Quincy Basin. She also wrote letters to her cousin at her residences in Kittitas and Quincy, Washington, following her time in Ellensburg.