Digital Commons Network^™

Exploring Intentional Medication Non-Adherence In Patients With Systemic Lupus Erythematosus: The Role Of Physician-Patient Interactions, Jerik Leung, Elizabeth A Baker, Alfred H J Kim

2020-Current year OA Pubs

OBJECTIVE: Medication non-adherence contributes to worse health outcomes among SLE patients. The underlying mechanisms that drive medication non-adherence are poorly understood. The purpose of this study was to explore possible mechanisms of medication non-adherence by eliciting patient experiences.

METHODS: Consented adult patients with ACR- or SLICC-classified SLE were recruited. Ten semi-structured interviews were conducted across six participants. Interviews were audio recorded, transcribed, and analysed using an iterative process. The findings were presented to an interactive public forum with SLE patients, family members and friends of patients, and health-care professionals to assess validity and for elaboration of the concepts developed.

RESULTS: …

After The Dust Settles: The Church And Public Affairs In 2020, Nicholas P. Miller

Faculty Publications

No abstract provided.

Sensing Population Distribution From Satellite Imagery Via Deep Learning:Model Selection, Neighboring Effects, And Systematic Biases, Xiao Huang, Di Zhu, Fan Zhang, Tao Liu, Xiao Li, Lei Zou

Geosciences Faculty Publications and Presentations

The rapid development of remote sensing techniques provides rich, large-coverage, and high-temporal information of the ground, which can be coupled with the emerging deep learning approaches that enable latent features and hidden geographical patterns to be extracted. This article marks the first attempt to cross-compare performances of popular state-of-the-art deep learning models in estimating population distribution from remote sensing images, investigate the contribution of neighboring effect, and explore the potential systematic population estimation biases. We conduct an end-to-end training of four popular deep learning architectures, i.e., VGG, ResNet, Xception, and DenseNet, by establishing a mapping between Sentinel-2 image patches and …

Validation Of Diffusion Mri As A Biomarker For Efficacy Using Randomized Phase Iii Trial Of Bevacizumab With Or Without Vb-111 In Recurrent Glioblastoma, Benjamin M Ellingson, Jian L Campian, Et Al.

2020-Current year OA Pubs

BACKGROUND: Evidence from single and multicenter phase II trials have suggested diffusion MRI is a predictive imaging biomarker for survival benefit in recurrent glioblastoma (rGBM) treated with anti-VEGF therapy. The current study confirms these findings in a large, randomized phase III clinical trial.

METHODS: Patients with rGBM were enrolled in a phase III randomized (1:1), controlled trial (NCT02511405) to compare the efficacy and safety of bevacizumab (BV) versus BV in combination with ofranergene obadenovec (BV+VB-111), an anti-cancer viral therapy. In 170 patients with diffusion MRI available, pretreatment enhancing tumor volume and ADC histogram analysis were used to phenotype patients as …

Carotid Artery Dissections From Tcar As Reported By The Food And Drug Administration, Dongjin Suh Bs, Yuchi Ma Bs, Daniel H. Newton Md, Michael F. Amendola Md, Kedar S. Lavingia Md

Graduate Research Posters

BACKGROUND: Transcarotid artery revascularization (TCAR) is hybrid procedure that allows carotid stenting using direct surgical access of the carotid artery to restore blood flow through the carotid artery. It has shown the lowest perioperative stroke rate when compared with any prospective trial of transfemoral carotid artery stenting. However, intraoperative injuries related to the procedure and its management are not well characterized. We anticipate that this analysis will add qualitative insight in further characterizing adverse outcomes of this novel technology.

METHODS: The FDA maintains a database called the MAUDE (Manufacturer and User Facility Device Experience) for surveillance of all medical devices …

Influence Of Telephone Preoperative Evaluations On Patient Medication Compliance On Day Of Surgery, Emmanuel Magsino, Michael Jung, Olga Suarez Md

Graduate Research Posters

Patient compliance with medication instructions on day of surgery (DOS) is an important part of the preoperative assessment, as failure to comply with these may lead to serious perioperative consequences. Prior studies have shown that compliance increases with multimodal interventions. However due to the recent COVID-19 pandemic, many in-person visits transitioned to telephone visits and providers had to rely on patients to follow solely verbal instructions.

To determine medication compliance, this study compared the medication instructions provided by the VCU Preoperative Assessment Communication and Education Clinic, per chart review, with each patient’s own report of which medications they took on …

Selective Gsk3b Deletion In Camk2a+ Forebrain Neurons Or Inhibition Via Tideglusib, Decreases Ethanol Consumption In C57bl/6j Mice, Sam Gottlieb, Andrew D. Van Der Vaart, Brennen O'Rourke, Michael F. Miles

Graduate Research Posters

Purpose: We previously identified glycogen synthase kinase-3 beta (Gsk3b) as a central member of a gene network highly regulated by acute ethanol in medial prefrontal cortex (mPFC) and associated with risk for alcohol dependence in humans. Further, we have demonstrated modulation of Gsk3b alters ethanol consumption in rodent models. GSK3B could thus represent a potential new therapeutic target for the treatment of alcohol use disorder (AUD). Here, we investigate the mechanisms of Gsk3b action in ethanol consumption and report preclinical evidence for the selective GSK3B inhibitor, tideglusib, as a therapeutic agent for AUD.

Methods: (1) Selective Cre-induced Gsk3b …

Cost-Effectiveness Of Alternative Hiv Testing Strategies Among Hard-To-Reach Populations In East And Southern Africa., Deo Mujwara, Deo Mujwara

Graduate Research Posters

No abstract provided.

Cultural Socialization And Ethnic-Racial Identity Mediated By Positive And Negative Conversations About Race: Exploring Differences Among Students Of Color And White Students, Maria J. Cisneros, Eryn Delaney, Chelsea D. Williams, Sabrina Hawa, Chloe Walker, Fantasy Lozada, Su Jinni, Danielle Dick

Graduate Research Posters

Objectives: The current study examined associations between cultural socialization and ethnic-racial identity (ERI) via positive and negative conversations about one’s ethnicity/race. Differences between students of color (SOC) and White students (WS) were explored.

Method: Diverse college students 18-22 (M age = 18.46) participating in a university-wide study provided self-reports of childhood cultural socialization, engagement in conversations about ethnicity/race during college, and ERI.

Results: Cultural socialization was associated with more positive conversations about race, and, in turn, greater ERI exploration, resolution, and affirmation among SOC and WS. Additionally, negative conversations about race were associated with greater ERI exploration and …

Text Mining To Identify The Origin Of Chronic Wasting Disease, G. Webb

Faculty Research, Scholarly, and Creative Activity

Chronic wasting  disease (CWD)  is  a 100  percent  fatal,  prion  disease of  deer  that  has  the potential  to decimate  the  deer  population and  jump to  the  human  population.   A  simple  Google  search on  the  “origin of  chronic wasting  disease” yielded  a total  of  56  relevant  articles.   Of  these,  75  percent  report  that  the origin  is  unknown,  19.6  percent  report  that  the  disease  may  have  originated  in  a  Fort  Collins,  Colorado, government  research facility, and 5.4 percent  report  other  possible  origins.  Government  sources  reported the  Fort  Collins  theory  4.3 percent  of  the  time  while  non-governmental  sources,  such  as news articles, reported …

5 Axis 3d Printer, Brian Dubois, Sarah Pudlo, Anthony White

Mechanical Engineering Capstone Design Projects

The following report is an overview of the Team 19H: Extra Dimensions project, a 5-Axis 3-D printer, produced over the Fall `20 and Spring `21. The project was presented by the Naval Undersea Warfare Center (NUWC), located in Newport, Rhode Island, and is sponsored by Nathan Wiebe. The problem is de ned as the design and construction of a 3D printer with two additional axes of rotation while staying within the given budget. Conventional 3D printers rely on support material while printing and lack the ability to produce complex geometries. Adding the additional axes can improve 3D printing by eliminating …

Camera Housing And Gamma Probe Extension, George Acker, Daniel Bor, Devesh Mistry, Pablo Vargas, Bahram Nassersharif

Mechanical Engineering Capstone Design Projects

Together with Team 10, Team 11 was tasked by Los Alamos National Laboratory to design a functioning Remotely-Operated Vehicle (ROV) that can examine nuclear fuel rods in an underwater nuclear reactor. Team 11 was specifically tasked with designing two important elements of the ROV; a camera housing, that could be easily be attached and detached from the underwater vehicle, and a method of detecting the strength of gamma radiation emitted by the fuel elements.

Team 11 worked closely with Team 10 to accomplish a sturdy and reliable design that utilizes mirrors to reflect an image for viewing by a camera. …

Acceptability Of An Intervention To Promote Viral Suppression And Serostatus Disclosure For Men Living With Hiv In South Africa: Qualitative Findings, Mxolisi Mathenjwa, Hazar Khidir, Cecilia Milford, Nzwakie Mosery, Letitia Rambally Greener, Madeline Pratt, Kasey O’Neil, Abigail Harrison, David R. Bangsberg, Steven A. Safren, Jennifer A. Smit, Christina Psaros, Lynn T. Matthews

OHSU-PSU School of Public Health Faculty Publications and Presentations

Men living with HIV ( MLWH ) often have reproductive goals that can increase HIV-transmission risks to their pregnancy partners. We developed a safer conception intervention for MLWH in South Africa employing cognitive behavioral skills to promote serostatus disclosure, ART uptake, and viral suppression. MLWH were recruited from an HIV clinic near Durban, South Africa, and encouraged to include partners in follow-up visits. Exit in-depth interviews were conducted with eleven men and one female partner. The emerging over-arching theme is that safer conception care mitigates internalized and community-level HIV-stigma among MLWH. Additional related sub-themes include: ( 1 ) safer conception …

When “Tried And True” Advocacy Strategies Backfire: Narrative Messages Can Undermine State Legislator Support For Early Childcare Policies, Liana B. Winett, Jeff Niederdeppe, Yiwei Xu, Sarah Gollust, Erika Franklin Fowler

OHSU-PSU School of Public Health Faculty Publications and Presentations

A core principle of policy advocacy is that to engage decision makers in the urgency, complexity, and controversy of problems, advocates must effectively tell the story of those issues. Policy stories, or narratives, paint mental pictures of what a problem is, who is affected, and how it came to be. Yet, the persuasive effects of narratives on one key group, state legislators, remain understudied. Drawing from the Narrative Policy Framework (NPF), media advocacy, and public interest communications, we sought to inform advocacy strategy by illuminating state legislators’ responses to messages about public investments in quality childcare for all. Contrary to …

Routinely Collected Antenatal Data For Longitudinal Prediction Of Preeclampsia In Nulliparous Women: A Population‑Based Study, Anna Sandstrom, Jonathan Snowden, Matteo Bottai, Olof Stephansson, Anna-Karin Wikström

OHSU-PSU School of Public Health Faculty Publications and Presentations

The objective was to evaluate the sequentially updated predictive capacity for preeclampsia during pregnancy, using multivariable longitudinal models including data from antenatal care. This population-based cohort study in the Stockholm-Gotland Counties, Sweden, included 58,899 pregnancies of nulliparous women 2008–2013. Prospectively collected data from each antenatal care visit was used, including maternal characteristics, reproductive and medical history, and repeated measurements of blood pressure, weight, symphysis-fundal height, proteinuria, hemoglobin and blood glucose levels. We used a shared-effects joint longitudinal model including all available information up until a given gestational length (week 24, 28, 32, 34 and 36), to update preeclampsia prediction sequentially. …

Annual Security Report For Calendar Year 2020, Illinois State University Police Department

Clery Act Annual Security Report

Illinois State University Police Department Annual Security Report

Small Business Disaster Relief And Restructuring, Brook Gotberg

Faculty Scholarship

To assist small businesses in the wake of an exogenous shock, Congress should consider implementing a system of lending that models the financing provided to small business debtors in a bankruptcy proceeding. Such a system would be more targeted, effective, and fair than traditional government loans, but less stigmatizing than bankruptcy.

Association Between Toxoplasma Gondii Seropositivity And Serointensity And Brain Volume In Adults: A Cross-Sectional Study, Bruce L. Brown, Lance D. Erickson, Shawn D. Gale, Dawson W. Hedges

Faculty Publications

The intracellular protozoal parasite Toxoplasma gondii has been associated with worsened cognitive function in animal models and in humans. Despite these associations, the mechanisms by which Toxoplasma gondii might affect cognitive function remain unknown, although Toxoplasma gondii does produce physiologically active intraneuronal cysts and appears to affect dopamine synthesis. Using data from the UK Biobank, we sought to determine whether Toxoplasma gondii is associated with decreased prefrontal, hippocampal, and thalamic gray-matter volumes and with decreased total gray-matter and total white-matter volumes in an adult community-based sample. The results from adjusted multivariable regression modelling showed no associations between Toxoplasma gondii and …

Grant, Miles (1819-1911), Denis Fortin

Faculty Publications

No abstract provided.

Voter Friendly Campus/All-In For Democracy, Election 2020 Final Report, Center For Civic Engagement

Reports and White Papers - Center for Civic Engagement

Illinois State University reports on their participation in the All-In Challenge and the Voter Friendly Campus initiative.

Research And Graduate Studies Annual Report, 2021, Office Of Research And Graduate Studies, Illinois State University

Research and Graduate Studies Annual Report

No abstract provided.

Treatment-Resistant Hypercalcemia From Ectopic Pth Hypersecretion Suspected Secondary To Disseminated Ovarian Cancer, Alexander M. Balinski, Neil J. Khatter, Jeffrey M. Gold, Krishna S. Pothugunta, Vamshi K. Garlapaty, Steven M. Rankin, Christopher A. Thornburn, Jamal Abu-Khaled

Articles

Hypercalcemia of malignancy (HCM) can present secondary to hypersecretion of parathyroid hormone (PTH)-related protein (PTHrP) from malignant tumors, but rare cases of HCM have also been documented due to inappropriate PTH secretion from ectopic neoplasms. Here, we report an unusual case of HCM due to hypersecretion of PTH suspected secondary to a disseminated mucinous ovarian adenocarcinoma. A 45-year-old female presented with severe hypercalcemia and significant elevations in both PTH and PTHrP two weeks after total abdominal hysterectomy with bilateral salpingo-oophorectomy and suboptimal debulking of a newly discovered left ovarian mucinous adenocarcinoma with numerous metastases. Ectopic PTH secretion was highly suspected …

Gene Selection For Cancer Classification: A New Hybrid Filter-C5.0 Approach For Breast Cancer Risk Prediction, Mohammed Hamim, Ismail El Moudden, Hicham Moutachaouik, Mustapha Hain

Department of Medicine Faculty Publications

Despite the significant progress made in data mining technologies in recent years, breast cancer risk prediction and diagnosis at an early stage using DNA microarray technology still a real challenging task. This challenge comes especially from the high-dimensionality in gene expression data, i.e., an enormous number of genes versus a few tens of subjects (samples). To overcome this problem of data imbalance, a gene selection phase becomes a crucial step for gene expression data analysis. This study proposes a new Decision Tree model-based attributes (genes) selection strategy, which incorporates two stages: fisher-score-based filter technique and the gene selection ability of …

A Novel Dimensionality Reduction Approach To Improve Microarray Data Classification, Mohammed Hasim, Ismail El Mouden, Mounir Ouzir, Hicham Moutachaouik, Mustapha Hain

Department of Medicine Faculty Publications

Cancer tumor prediction and diagnosis at an early stage has become a necessity in cancer research, as it provides an increase in the treatment success chances. Recently, DNA microarray technology became a powerful tool for cancer identification, that can analyze the expression level of a different and huge number of genes simultaneously. In microarray data, the large genes number versus a few records may affect the prediction performance. In order to handle this "curse of dimensionality” constraint of microarray dataset while improving the cancer identification performance, a dimensional reduction phase is necessary. In this paper, we proposed a framework that …

A Longitudinal Study Of Interprofessional Education In Graduate Students From Rehabilitation Sciences, Sarah Elkington, Connie Summers, Celia Pechak, Patricia Lara, Francesca Hernandez

Faculty Publications

• Date Presented Accepted for AOTA INSPIRE 2021 but unable to be presented due to online event limitations. A longitudinal study evaluated the effects of interprofessional education (IPE) experiences on 71 rehabilitation science graduate students' perceptions of interprofessional collaboration (IPC). Physical therapy, OT, and speech-language pathology students rated their perceptions of IPC and their knowledge of other disciplines' roles across their first year of graduate school. IPE experiences are an important aspect of professional preparation. Primary Author and Speaker: Sarah Elkington Contributing Authors: Connie Summers, Celia Pechak, Patricia Lara, and Francesca Hernandez

The Effect Of Amplification On Cortical Synchrony In Children With Auditory Neuropathy Spectrum Disorder, Garrett Cardon, Anu Sharma

Faculty Publications

Objective: The benefit of hearing aids as a clinical intervention strategy for children with Auditory Neuropathy Spectrum Disorder (ANSD) remains controversial. The goal of this study was to determine whether amplification through hearing aid use increased cortical phase synchrony in children with ANSD. Design: Using inter-trial coherence (ITC) of the EEG signal as a measure of cortical phase-locking, we examined differences in cortical phase synchrony in children with ANSD using both cross-sectional and longitudinal designs. Study Sample: Participants in the cross-sectional and longitudinal portions of the study included 58 and 16 children with clinical diagnoses of ANSD, respectively. Results: Results …

Psychotherapy Utilization And Presenting Concerns Among International Asian And Asian American Students In A University Counseling Center., Hannah Stokes, Derek Griner, Timothy B. Smith, Mark Beecher, G. E. Kawika Allen, Jon Cox, Klint Hobbs, Natalie Ann Kirtley

Faculty Publications

Limited psychological research has disaggregated the experiences of Asian American (AA) from international Asian (IA) college students seeking psychotherapy. When combined, important differences between these groups are overlooked. We examined archival data collected from AA, IA, and European American (EA) students at a large, Western, university counseling center. Results indicated no significant differences between groups related to maximum number of psychotherapy sessions attended or likelihood of treatment discontinuance. However, we found significant differences between these groups on a number of items related to presenting concerns and to severity of presenting distress, with IA students presenting with the most distress, followed …

Recruiting And Retaining School Psychologists: The Role Of District Level Administrative Supervisors, Ellie L. Young, Rachel Butler, Timothy B. Smith, Sterling Hilton, Alivia Smith

Faculty Publications

A shortage of school psychologists has been evident since the profession was initially recognized as a distinct field, and there is insufficient research on what current administrative supervisors are doing to address this problem. This qualitative study examined the perceptions of district level administrative supervisors regarding recruitment and retention of school psychologists. Participants reported the following: (a) school psychology graduate programs not producing enough school psychologists, (b) challenges of finding school psychologists to hire, (c) competing with neighboring school districts, and (d) trying to recruit and retain in a worker’s market that favors the school psychologist. These administrative supervisors also …

Student Affairs Viewbook, 2021-2022, Division Of Student Affairs, Illinois State University

Student Affairs Viewbook

No abstract provided.

Access Denied: How 28 U.S.C. Sec. 1915(G) Violates The First Amendment Rights Of Indigent Prisoners, Molly Guptill Manning

Articles & Chapters

No abstract provided.