Digital Commons Network^™

Amazon Reviews Using Sentiment Analysis, Ammar Rashed Hamdallah

Theses

The intense competition to attract and maintain customers online is compelling businesses to implement novel strategies to enhance the customer experiences. It is becoming necessary for companies to examine customer reviews on online platforms such as Amazon to understand better how customers rate their products and services. The purpose of this study is to investigate how companies can conduct sentiment analysis based on Amazon reviews to gain more insights into customer experiences. The dataset selected for this capstone consists of customer reviews and ratings from consumer reviews of Amazon products. Amazon product reviews enable a business to gain insights on …

License To Heal: Understanding A Healthcare Platform Organization As A Multi-Level Surveillant Assemblage, Handan Vicdan, Mar Pérezts, Asım Fuat Fırat

Management Faculty Publications

Platform organizations bring renewed attention to power disparities and risks in the rise of surveillance capitalism. However; such critical accounts provide a partial understanding of the complexity of surveillance phenomena in such shifting socio-technical and digital environments.The findings from a netnographic investigation of a healthcare platform organization, PatientsLikeMe, unravel how platforms become the locus where multi-level flows of surveillance converge, thereby constituting what we identify as a surveillant assemblage. We develop a comprehensive approach for understanding how platforms constitute a dynamic crossroads of micro-, meso- and macro-surveillance phenomena within and beyond the online communities they create.This study highlights this surveillant …

Characterization Of Bacteriophage Targeting Bacillus Licheniformis In Milk Processes And Thermal Stability Of Bacteriophage During Htst Pasteurization, Jeremy Robert Arbon

Theses and Dissertations

An array of Bacillus licheniformis strains were isolated from a commercial powdered milk process. Bacteriophages exhibiting activity against B. licheniformis were isolated from cattle manure and effluent samples destined for a lagoon at a dairy farm. After sequencing, 8 of the 10 phages were found to be novel and genetically differentiated. Transmission electron scanning microscopy (TSEM) was performed. All bacteriophages were of the family Herelleviridae with contractile tail sheaths ranging from 80µm to 150µm and, surprisingly, survived a common fluid milk processing treatment used to inactivate vegetative cells. The survival of the phage after high temperature short time pasteurization of …

Pervasiveness Of Library Anxiety Among The Students Of Library And Information Science: An Assessment, Mahe Bushra Asghar, Rubina Bhatti, Salman Bin Naeem

Library Philosophy and Practice (e-journal)

Library anxiety is a real and prevalent phenomenon. Some students feel uncomfortable or discouraging while using or contemplating the use of library. These feelings may affect the academic performance of students, cause library avoidance and impede them from getting the best out of library resources. The present study is conducted with an aim to assess the pervasiveness of library anxiety among the graduate students of Library and Information Science enrolled in public sector universities of Pakistan. . The Multidimensional Library Anxiety Scale, consisting of six dimensions which are divided into 53 statements, was used for this study. The Cronbach’s alpha …

Political-Pedagogical Character Of The Collective Actions Of The Popular Bars, Magda Victoria Díaz Alzate Sra, Juan Pablo Menjura Acosta Sr, Maria Clara Fonseca Echeverri Sra

The Qualitative Report

Barrismo is a complex phenomenon and cannot be defined universally. Social representation is based on deficient conceptions that relate it to the use of psychoactive substances and violence. This article presents qualitative research evidence based on the epistemological assumptions of social constructionism, a hermeneutical phenomenological design and the use of qualitative interview and documentary and audiovisual review, to understand the political-pedagogical character of the collective actions of the popular bars of the city of Medellín, Colombia, as practices that contribute to the transformation of the territories. Categories found: i. Bars as popular movements: transition from the brave bar to the …

Multicenter Randomized Phase Ii Trial Of Atezolizumab With Or Without Cobimetinib In Biliary Tract Cancers, Mark Yarchoan, Andrea Wang-Gillam, Et Al

Open Access Publications

BACKGROUNDMEK inhibitors have limited activity in biliary tract cancers (BTCs) as monotherapy but are hypothesized to enhance responses to programmed death ligand 1 (PD-L1) inhibition.METHODSThis open-label phase II study randomized patients with BTC to atezolizumab (anti-PD-L1) as monotherapy or in combination with cobimetinib (MEK inhibitor). Eligible patients had unresectable BTC with 1 to 2 lines of prior therapy in the metastatic setting, measurable disease, and Eastern Cooperative Oncology Group (ECOG) performance status less than or equal to 1. The primary endpoint was progression-free survival (PFS).RESULTSSeventy-seven patients were randomized and received study therapy. The trial met its primary endpoint, with a …

Utility Of Facebook's Social Connectedness Index In Modeling Covid-19 Spread: Exponential Random Graph Modeling Study, Beth Prusaczyk, Kathryn Pietka, Joshua M Landman, Douglas A Luke

Open Access Publications

BACKGROUND: The COVID-19 (the disease caused by the SARS-CoV-2 virus) pandemic has underscored the need for additional data, tools, and methods that can be used to combat emerging and existing public health concerns. Since March 2020, there has been substantial interest in using social media data to both understand and intervene in the pandemic. Researchers from many disciplines have recently found a relationship between COVID-19 and a new data set from Facebook called the Social Connectedness Index (SCI).

OBJECTIVE: Building off this work, we seek to use the SCI to examine how social similarity of Missouri counties could explain similarities …

Adsorpsi Senyawa Organik Pada Lindi Menggunakan Cangkang Kerang Ale-Ale (Meretrix Meretrix) Secara Batch, Yulistya Vidyaning Maulidya, Rudiyansyah Rudiyansyah, Nelly Wahyuni

Chimica et Natura Acta

Penimbunan sampah di TPA Batu Layang, Pontianak, Kalimantan Barat menyebabkan terbentuknya air lindi yang memiliki konsentrasi COD sangat tinggi. Hal tersebut menyebabkan dampak buruk terhadap lingkungan dan kesehatan. Pengolahan air lindi secara sederhana dapat dilakukan menggunakan metode adsorpsi. Penelitian ini bertujuan untuk mengetahui variasi waktu kontak, massa adsorben, dan kecepatan pengadukan optimum terhadap efisiensi adsorpsi. Karakterisasi menggunakan FTIR terhadap adsorben cangkang kerang ale-ale menunjukan adanya puncak pada bilangan gelombang 1452 cm-1, 852 cm-1, dan 716 cm-1 yang menandakan keberadaan gugus C-O. Pengukuran konsentrasi COD pada penelitian ini dilakukan secara titrasi permanganometri. Adsorpsi keadaan optimum diperoleh pada massa 4,5 g dengan …

Investigating Antimicrobial Properties Of Snake Venoms Against B. Cereus, B. Subtilis, E. Coli, And P. Vulgaris, Savannah Elaine Berger

Honors Program Theses and Research Projects

The increasing incidence of antibiotic resistant bacterial infections has provoked the attention of health officials and scientists as a major threat to global public health. Antibiotic resistance is the product of overprescription by doctors, ineffective or shortened dosing by the patient, and more. When a bacterial infection is ineffectively treated as such, persistent pathogenic cells are given the opportunity to proliferate and spread their resistance to other cells. With bacteria utilizing such tools to fight and ultimately resist our current treatment methods, investigation towards the next novel mechanism of inhibition is essential. Venom is of particular interest to many scientists …

Working Paper No. 53, Mexico Under Neoliberalism, Daniela M. Ávila Arévalo

Working Papers in Economics

This inquiry seeks to establish that a set of policies that can be identified as ‘neoliberalism’ has generated observable effects on the economy and society of Mexico. Initiated during the last decades of the twentieth century, a combination of external and internal interests led to the implementation of neoliberal policies. The marketization of Mexico’s economy during the 1980s and 90s consolidated ‘structural adjustments.’ Through extensive privatization of what were statist assets, combined with the deregulation of trade as well as numerous aspects of private sector activity, the Mexican economy came to rely upon a low-wage labor export-model that also undermined …

Acculturation Strategies And Pap Screening Uptake Among Sub-Saharan African Immigrants (Sais), Adebola Adegboyega, Jia-Rong Wu, Gia Mudd-Martin

Nursing Faculty Publications

Although regular cervical cancer screening can prevent cervical cancer, screening utilization remains low among immigrant population including sub-Saharan African immigrants (SAIs). Acculturation is a complex process, which can lead to adoption of positive or negative health behaviors from the dominant culture. Acculturation strategies are the varying ways in which individuals seek to go about their acculturation by either maintaining or rejecting their own cultural values ip or accepting or rejecting the host culture's cultural values. Cervical cancer screening behaviors among SAI women may be influenced by their acculturation strategies. We conducted a secondary analysis of data to examine the relationship …

The Great Commission: An Exegetical And Theological Study Of Matt 28:16-20 In The Northern Nigeria Context, Vincent K. Sebastine

Seton Hall University Dissertations and Theses (ETDs)

ABSTRACT

Scholars refer to the passage on Matthew 28:16-20 as the “Great Commission”. It concludes the last part of the Gospel of Matthew (26:1-28:20), that is, Jesus’ passion, death and resurrection. In the Great Commission scene – on the mountain in Galilee (Matt 28:16), Jesus speaks to his disciples about his authority, commissions them to make disciples - by baptizing and teaching - and gives them an assurance of his abiding presence. This passage contains several themes – mountain, worship, authority and nations – which relate to the Gospel and other text in the Bible. It is pertinent to note …

Office Of Research, Economic Engagement And Outreach Update, December 15, 2021, Office Of Research, Economic Engagement And Outreach

Office of Research, Economic Engagement and Outreach

No abstract provided.

Evaluating Recognition Memory Models From An Individual Differences Perspective, Kyle Gramer Featherston

Arts & Sciences Graduate Student Theses and Dissertations

Although recognition memory models have been thoroughly compared in various recognition memory paradigms, the relative reliability and validity of their parameters have not been thoroughly assessed using an individual differences approach. In two studies, I evaluated three models: the dual-process signal detection (DPSD) model, the continuous dual process (CDP) model, and the unequal variance signal detection (UVSD) model. In Study 1, participants performed a remember-know procedure that also included confidence ratings. When model parameters were estimated twice in the same individual, both key parameters from the DPSD model were reliable within an individual, whereas the CDP version of familiarity was …

The Effects Of Molecular Chaperone Modulation On Protein Folding, Prion Formation, And Prion Propagation In Saccharomyces Cerevisiae, Leeran Blythe Dublin Ryan

Arts & Sciences Graduate Student Theses and Dissertations

Proper and efficient protein folding is vital for cell survival. Many factors affect protein folding fidelity and prion formation, including molecular chaperone availability and activity. Research has shown that modulating chaperone availability and function can affect protein misfolding and aggregation, as well as de novo prion formation and propagation. However, the factors involved and underlying mechanisms influencing prion formation and protein folding are largely unknown. The following work aims to elucidate these areas. The Nascent Polypeptide-Associated Complex (NAC) is the first point of chaperone contact for nascent polypeptides. Previous work has shown that disruption of the NAC leads to improved …

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Newsroom, Georgia Southern University

Newsroom (2006-2023)

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Personal And Social Compatibility And Its Relationship To The Control Center For The Children Of Kindergarten, Bayda Abdulsalam

Alustath Journal for Human and Social Sciences

The current study aims to identify personal and social compatibility and its Relationship to the Control Center for the Children of Kindergarten. The sample included (100) children from kindergartens in the city of Baghdad. In order to achieve the research objectives, identifying personal and social compatibility after studying the theories and previous studies related to her research. Identifying personal and social compatibility in its final form (27) paragraph and gave each position three alternatives While Locus of control scale in final phase includes (10) items The researcher has verified the psychological standard characteristics The researcher has reached to the following: …

Psychological Assessment And Testing, Leslie A. Miller, Ruby Daniels

Marketing Faculty Publications (Archived)

No abstract provided.

Ward Based Goal Directed Fluid Therapy (Gdft) In Acute Pancreatitis (Gap) Trial: A Feasibility Randomised Controlled Trial [Isrctn 36077283], F Froghi, F Soggiu, F Ricciardi, C Vindrola-Padros, L Floros, D Martin, H Filipe, M Varcada, K Gurusamy, S Bhattacharya, A Fanshawe, B Dolcea, P Mathur, B Davidson

Peninsula Medical School

Background: Goal-directed fluid therapy (GDFT) reduces complications in patients undergoing major general surgery. There are no reports of cardiac output evaluation being used to optimise the fluid administration for patients with acute pancreatitis (AP) in a general surgery ward. Method: 50 patients with AP were randomised to either ward-based GDFT (n=25) with intravenous (IV) fluids administered based on stroke volume optimisation protocol or standard care (SC) (n=25), but with blinded cardiac output evaluation, for 48-hours following hospital admission. Primary outcome was feasibility. Results: 50 of 116 eligible patients (43.1%) were recruited over 20 months demonstrating feasibility. 36 (72%) completed the …

Visual Field Progression In Glaucoma: Comparison Between Poplr And Answers, Iván Marín-Franch, Paul H. Artes, Andrew Turpin, Lyne Racette

School of Health Professions

No abstract provided.

Epidemiological Studies On Risk Factors Of Chronic Diseases, Rutu Rathod

Electronic Theses and Dissertations Archive

Myocardial Infarction (MI) is one of the most common cardiac conditions in older adults. As the pathophysiological processes underlying human diseases are complex, I utilized all available data to predict the incidence of future MI using exploratory factor analysis. Six factors were identified, each representing a unique risk dimension based on loaded observed variables, e.g., the hemodynamic factor loaded systolic, diastolic blood pressure, and heart rate variables. Four factors (hemodynamic, smoking, blood lipids, and alcohol consumption) were detected as risk factors for future MI. The burden of chronic conditions among children and adolescents is increasing and one of its risk …

Racial/Ethnic Differences In The Relationship Between Wealth And Health, Sicong Sun

Brown School Graduate Student Theses and Dissertations

Racial wealth inequity is one of the most pressing social and economic issues in the United States, historically and contemporarily. Primarily due to unequal distribution of opportunity for economic advancement and mobility in addition to the accumulation of historic disadvantage endured by Black and Latinx Americans, U.S. racial wealth inequity leads to substantial racial health disparities. It is widely acknowledged that socioeconomic position (SEP) is a fundamental cause of disease and health disparities. Centering around three key constructs—race/ethnicity, wealth, and health—this dissertation had two overarching aims: (a) to investigate the relationship between wealth and health, delineating the effects of wealth …

Lrg1 Is An Adipokine That Mediates Obesity-Induced Hepatosteatosis And Insulin Resistance, Sijia He, Jiyoon Ryu, Juanhong Liu, Hairong Luo, Ying Lv, Paul R. Langlais, Jie Wen, Feng Dong, Zhe Sun, Ravindranath Duggirala

School of Medicine Publications

Dysregulation in adipokine biosynthesis and function contributes to obesity-induced metabolic diseases. However, the identities and functions of many of the obesity-induced secretory molecules remain unknown. Here, we report the identification of leucine-rich alpha-2-glycoprotein 1 (LRG1) as an obesity-associated adipokine that exacerbates high fat diet–induced hepatosteatosis and insulin resistance. Serum levels of LRG1 were markedly elevated in obese humans and mice compared with their respective controls. LRG1 deficiency in mice greatly alleviated diet-induced hepatosteatosis, obesity, and insulin resistance. Mechanistically, LRG1 bound with high selectivity to the liver and promoted hepatosteatosis by increasing de novo lipogenesis and suppressing fatty acid β-oxidation. LRG1 …

Stat3 Inhibitor Mitigates Cerebral Amyloid Angiopathy And Parenchymal Amyloid Plaques While Improving Cognitive Functions And Brain Networks, Jogender Mehla, Itender Singh, Deepti Diwan, James W Nelson, Molly Lawrence, Eunjae Lee, Adam Q Bauer, David M Holtzman, Gregory J Zipfel

2020-Current year OA Pubs

Previous reports indicate a potential role for signal transducer and activator of transcription 3 (STAT3) in amyloid-β (Aβ) processing and neuritic plaque pathogenesis. In the present study, the impact of STAT3 inhibition on cognition, cerebrovascular function, amyloid pathology, oxidative stress, and neuroinflammation was studied using in vitro and in vivo models of Alzheimer's disease (AD)-related pathology. For in vitro experiments, human brain vascular smooth muscle cells (HBVSMC) and human brain microvascular endothelial cells (HBMEC) were used, and these cultured cells were exposed to Aβ peptides followed by measurement of activated forms of STAT3 expression and reactive oxygen species (ROS) generation. …

P-P06 Ward Based Goal Directed Fluid Therapy (Gdft) In Acute Pancreatitis (Gap) Trial: A Feasibility Randomised Controlled Trial [Isrctn 36077283], F Froghi, F Soggiu, F Ricciardi, C Vindrola-Padros, L Floros, D Martin, H Filipe, M Varcada, K Gurusamy, S Bhattacharya, A Fanshawe, B Dolcea, P Mathur, B Davidson

Peninsula Medical School

No abstract provided.

Transcriptional Reprogramming Differentiates Active From Inactive Esr1 Fusions In Endocrine Therapy-Refractory Metastatic Breast Cancer, Xuxu Gou, Shunqiang Li, Et Al.

2020-Current year OA Pubs

Genomic analysis has recently identified multiple

Steps Beyond Risk Assessment In Qrm: Rbdm, The Next Horizon, Valerie Mulholland, Anne Greene, Martin J. Lipa

Level 3

The topic of Risk-based Decision Making (RBDM) was highlighted as one of these areas requiring clarification in the International Committee on Harmonisation (ICH) concept paper for the revision of Q9. This paper examines 5 key areas on RBDM identified in the concept paper, focusing on: What good risk-based decision making actually means, How QRM may improve decision-making and How risk-based decisions might be achieved. This was executed by reviewing peer-reviewed published research literature and examining best practices in other industries, with a view to initiating a dialogue which could help advance the questions posed. Based on this analysis, a list …

“Gaining Organisational Acceptance Of A Data Analytics Programme In Eli Lilly”, Anthony Maguire, Marcus O'Mahony

Level 3

This paper describes how Eli Lilly overcame barriers to enable new use of data. This was achieved by adopting a deep understanding of end-user needs and the support of site leaders and end-users to standardise process monitoring. A standard approach of ‘Contexting’, ‘Data-Extraction’, ‘Model build’, ‘On-line Config’, ‘Deploy’, was utilised, using a commercial off-the-shelf software. The paper describes proof of concept demonstrations undertaken and discusses the ingredients to make the journey a success.

“Data Architecture For Pharmaceutical Product Development At Alkermes”, Peter Couture, Damon Warnock, Marcus O'Mahony

Level 3

This paper describes how Alkermes built a data architecture for efficient management of non-GXP and R&D data. Using a ‘Create’, ‘Store’, Describe’ ‘Access’ stepwise model, the ingredients to making the journey a success are described.