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Articles 44281 - 44286 of 44286
Full-Text Articles in Entire DC Network
Identifying Specific Matrix Metalloproteinase-2-Inhibiting Peptides Through Phage Display-Based Subtractive Screening, Ayli̇n Özdemi̇r Bahadir, Bertan Koray Balcioğlu, Müge Serhatli, Şeyma Işik, Berri̇n Erdağ
Identifying Specific Matrix Metalloproteinase-2-Inhibiting Peptides Through Phage Display-Based Subtractive Screening, Ayli̇n Özdemi̇r Bahadir, Bertan Koray Balcioğlu, Müge Serhatli, Şeyma Işik, Berri̇n Erdağ
Turkish Journal of Biology
Gelatinases A and B, which are members of the matrix metalloproteinase (MMP) family, play essential roles in cancer development and metastasis, as they can break down basal membranes. Therefore, the determination and inhibition of gelatinases is essential for cancer treatment. Peptides that can specifically block each gelatinase may, therefore, be useful for cancer treatment. In this study, subtractive panning was carried out using a 12-mer peptide library to identify peptides that block gelatinase A activity (MMP-2), which is a key pharmacological target. Using this method, 17 unique peptide sequences were determined. MMP-2 inhibition by these peptides was evaluated through zymogram …
Fairness, Voice, Dialogue: Measuring Collective Social Justice In Schools, Craig Howley, Aimee Howley, Marged Dudek, Courtney Gilday
Fairness, Voice, Dialogue: Measuring Collective Social Justice In Schools, Craig Howley, Aimee Howley, Marged Dudek, Courtney Gilday
Mid-Western Educational Researcher
The United States is an inequitable society growing more inequitable in recent decades, and schooling is both part mechanism of oppression and part pathway toward social justice. Improving the extent to which schooling actually contributes to equity, however, depends on efforts to cultivate educator practices that advance social justice. Defining these practices and measuring their use among school faculties are necessary parts of the improvement process. Unfortunately, adequate measures of collective social justice practice in schools have not been developed for use with teachers. Based on a conception of social just as a three-part structure, we report progress on developing …
Voice For Change: Model Of Investment Theory In Professional Development For School Administrators, Iwona Lech, James Cohen
Voice For Change: Model Of Investment Theory In Professional Development For School Administrators, Iwona Lech, James Cohen
Mid-Western Educational Researcher
This paper is a result of an intensive four-day summer academy designed for administrators and auxiliary staff to be introduced to the world of the English Learner (EL). Although over 95 participants participated in this study, we selected one participant as the focal person for this paper. It presents how one school principal changed and developed as a result of participating in the Summer Academy. In particular, using Investment Theory (Darvin & Norton, 2015) as the theoretical lens we discuss three areas where the Summer Academy played a role in how William viewed and approached working with others: 1) the …