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2021

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Anticipating And Adapting To The Future Impacts Of Climate Change On The Health, Security And Welfare Of Low Elevation Coastal Zone (Lecz) Communities In Southeastern Usa, Thomas Allen, Joshua Behr, Anamaria Bukvic, Ryan S.D. Calder, Kiki Caruson, Charles Connor, Christopher D'Elia, David Dismukes, Robin Ersing, Rima Franklin, Jesse Goldstein, Jonathon Goodall, Scott Hemmerling, Jennifer Irish, Steven Lazarus, Derek Loftis, Mark Luther, Leigh Mccallister, Karen Mcglathery, Molly Mitchell, William Moore, Charles Reid Nichols, Karinna Nunez, Matthew Reidenbach, Julie Shortridge, Robert Weisberg, Robert Weiss, Lynn Donelson Wright, Meng Xia, Kehui Xu, Donald Young, Gary Zarillo, Julie C. Zinnert Jan 2021

Anticipating And Adapting To The Future Impacts Of Climate Change On The Health, Security And Welfare Of Low Elevation Coastal Zone (Lecz) Communities In Southeastern Usa, Thomas Allen, Joshua Behr, Anamaria Bukvic, Ryan S.D. Calder, Kiki Caruson, Charles Connor, Christopher D'Elia, David Dismukes, Robin Ersing, Rima Franklin, Jesse Goldstein, Jonathon Goodall, Scott Hemmerling, Jennifer Irish, Steven Lazarus, Derek Loftis, Mark Luther, Leigh Mccallister, Karen Mcglathery, Molly Mitchell, William Moore, Charles Reid Nichols, Karinna Nunez, Matthew Reidenbach, Julie Shortridge, Robert Weisberg, Robert Weiss, Lynn Donelson Wright, Meng Xia, Kehui Xu, Donald Young, Gary Zarillo, Julie C. Zinnert

Political Science & Geography Faculty Publications

Low elevation coastal zones (LECZ) are extensive throughout the southeastern United States. LECZ communities are threatened by inundation from sea level rise, storm surge, wetland degradation, land subsidence, and hydrological flooding. Communication among scientists, stakeholders, policy makers and minority and poor residents must improve. We must predict processes spanning the ecological, physical, social, and health sciences. Communities need to address linkages of (1) human and socioeconomic vulnerabilities; (2) public health and safety; (3) economic concerns; (4) land loss; (5) wetland threats; and (6) coastal inundation. Essential capabilities must include a network to assemble and distribute data and model code to …


Preclassic Cultural Eutrophication Of Lake Petén Itzá, Lowland Guatemala, By The Early Maya Of Nixtun-Ch'ich', Brooke A. Birkett Jan 2021

Preclassic Cultural Eutrophication Of Lake Petén Itzá, Lowland Guatemala, By The Early Maya Of Nixtun-Ch'ich', Brooke A. Birkett

Masters Theses

"Paleolimnological evidence indicates the ancient Maya transformed lowland terrestrial ecosystems by felling forest vegetation to construct large civic-ceremonial centers and expand agriculture. The effects of prehistoric Maya land alterations on lake trophic status, however, remain poorly understood. We analyzed a 515-cm-long sediment core from Lake Petén Itzá, lowland Guatemala, to infer paleoenvironmental changes resulting from Maya occupation of the riparian archaeological site of Nixtun-Ch'ich'. Substantial increases in charcoal and fecal stanol concentrations indicate Maya occupation of the Candelaria Peninsula by the late Early Preclassic period beginning ca. 1400 cal yr Before the Common Era (hereafter BCE), despite scant archaeological evidence …


Variational Inference For Morphological Modification To 3d Geometry : An Application To The Support Generation For Metal Additive Manufacturing, Mugdha Swanand Joshi Jan 2021

Variational Inference For Morphological Modification To 3d Geometry : An Application To The Support Generation For Metal Additive Manufacturing, Mugdha Swanand Joshi

Masters Theses

"A key issue in metal additive manufacturing (AM) processes is the optimization of support geometry. Correct selection of support strategy can reduce build time, improve surface finish, reduce support removal time, and maximize build success. Strategies used to design support structure are time consuming and need skilled personnel. In this research we have deployed a deep generative model capable of making morphological modifications to the part. However, it is not similar to topology optimization where the aim is to reduce or eliminate support structure. The proposed model can make necessary changes to the part in order to transform it into …


The Validation Of Predicted Biological Age Of Drosophila Melanogaster From Combined Statistical Modeling, Lauren Francis Jan 2021

The Validation Of Predicted Biological Age Of Drosophila Melanogaster From Combined Statistical Modeling, Lauren Francis

Masters Theses

"Sleep is essential for maintaining a healthy body and mind and is associated with aging and aging related diseases. There are individual differences in fly as well as human sleep behavior and lifespan. Between and within individuals, sleep varies in characteristics including consolidation, rhythmicity, continuity, duration, and more. Various evidence in the literature suggests there are many molecular pathways involved with aging and they may be different for individuals. Our research is interested in a possible restorative mechanism of sleep and the ramifications of that mechanism to aging. We have developed two predictive models of aging using the fruit fly …


Design And Development Of A Variable Resistance Hand Exerciser Using A Compliant Mechanism, Jyothi Komatireddy Jan 2021

Design And Development Of A Variable Resistance Hand Exerciser Using A Compliant Mechanism, Jyothi Komatireddy

Masters Theses

"Rehabilitation exercise plays a vital role in recovering from an injury or illness condition by improving flexibility and restoring muscle strength. If not done correctly, exercising can cause more damage to the health condition than in healing. Understanding the muscle’s resistance level while performing an exercise helps design the exercising equipment not to overstrain the muscle during operation. This research presents a methodology to develop a variable-resistance hand exerciser by using a compliant cam-follower mechanism. The proposed design comprised a compliant follower and a rigid cam. The rigid cam is synthesized using the human hand force-deflection profile as an input …


Exploring The Rhetorical Constitution Of A Safe Space For Women In Begum Rokeya And Frances Ellen Watkins Harper's Works, Rifat Rezowana Siddiqui Jan 2021

Exploring The Rhetorical Constitution Of A Safe Space For Women In Begum Rokeya And Frances Ellen Watkins Harper's Works, Rifat Rezowana Siddiqui

Dissertations and Theses @ UNI

This thesis studies the literary texts of two womanist authors, Begum Rokeya and Frances E. W. Harper, who are from different cultural and geographical background. The thesis attempts to uncover how both authors envision feminist utopian safe space for women of their society. Being the representative from the global south, Rokeya elaborates on 19th century social customs such as purdah and zenana to demonstrate sex segregation in her society. Harper, on the other hand, illustrates the social crisis of slavery and racism through her work. Criticizing the social norms that create obstacles for racialized women, both the authors assert the …


Agrochemicals And Rural Women's Health In The Volta Region Of Ghana, Sedomda Kpikpitse Jan 2021

Agrochemicals And Rural Women's Health In The Volta Region Of Ghana, Sedomda Kpikpitse

Dissertations and Theses @ UNI

Steered by the demand to improve and increase farm production, agrochemicals are regularly used by many farmers globally. However, agrochemical usage has contributed to many chronic illnesses experienced by users such as reproductive disorders, different kinds of cancers, and some chronic respiratory diseases. There are several regional and global coalitions to regulate the prevalence of agrochemicals to ensure their safe usage. Even though people can have access to some approved chemicals, the proper handling of these chemicals is not guaranteed. Many qualities of the person handling the chemical could increase or reduce the risk associated with agrochemicals. The behavior of …


Translation Into Spanish, Cultural Adaption And Content Validity Of The Bristol Copd Knowledge Questionnaire, Vilma Gómez Jan 2021

Translation Into Spanish, Cultural Adaption And Content Validity Of The Bristol Copd Knowledge Questionnaire, Vilma Gómez

Dissertations and Theses @ UNI

COPD is the major cause of respiratory mortality world-wide. The treatment of COPD includes education and self-management to enable patients to control the symptoms, handle the treatment, manage the physical and psychosocial consequences of the disease, and adopt the necessary lifestyle changes for dealing with a chronic condition. Measurement of results of interventions is necessary to demonstrate their effectiveness. Questionnaires help clinicians measure the level of knowledge before and after treatments. However, there are no questionnaires available in Colombian Spanish to measure knowledge of Chronic Obstructive Pulmonary Disease (COPD). This research resulted in the translation into Spanish, cultural adaptation, and …


Biochemical Assay Invariant Attestation For The Security Of Cyber-Physical Digital Microfluidic Biochips, Fredrick Eugene Love Ii Jan 2021

Biochemical Assay Invariant Attestation For The Security Of Cyber-Physical Digital Microfluidic Biochips, Fredrick Eugene Love Ii

Masters Theses

“Due to the devastating global impact that infectious diseases have had, especially in developing countries, the demand for access to adequate resources to combat sickness continues to be a heavy burden. Reliable and affordable diagnostics is a vital first line of defense in fighting outbreaks and providing accurate treatment. Digital microfluidics biochips capable of running multiple diagnostic tests on a single platform are an emerging technology that are increasingly being evaluated as a viable platform for rapid diagnosis and point-of-care field deployment. Although these systems offer many benefits, processing errors are inherent. Therefore, cyber-physical digital biochips are being investigated that …


Airbnbs In The Rural Midwest: Optimizing Listing Content For User’S Decision-Making Processes, Mary Catherine Kosacki Jan 2021

Airbnbs In The Rural Midwest: Optimizing Listing Content For User’S Decision-Making Processes, Mary Catherine Kosacki

Masters Theses

This research examines the effectiveness of rural Airbnb listing content in influencing user decision-making. The peer-to-peer economy has been rapidly growing over the past decade, providing new opportunities for individuals to offer goods and services to other individuals through corporate platforms. Specifically, the Airbnb platform has rapidly grown, becoming the largest online platform for peer-to-peer property rentals, and one of the largest companies in the peer-to-peer sector of the economy. Previous research on the Airbnb platform has focused primarily on urban areas; however, Airbnbs have a proportionally large impact on local economies in rural areas.

Several methods were employed to …


Analysis And Design Of Dc-Link Capacitor In Cascaded H-Bridge Multilevel Active Front-End Converter, Muhammad Shehroz Malik Jan 2021

Analysis And Design Of Dc-Link Capacitor In Cascaded H-Bridge Multilevel Active Front-End Converter, Muhammad Shehroz Malik

Masters Theses

Medium-voltage grid-tied systems often use a cascaded H-bridge multi-level active front-end. In this converter, dc link bus capacitors play an important role in stabilizing the converter and enabling both active and reactive power injections. The present work provides analytical expressions for the capacitor current, which are essential for optimizing system design (especially capacitor size vs. lifetime). Then, the expression is incorporated into the grid connected bidirectional power system model. Consequently, this work contributes to the guiding principles to choose accurate dc link capacitor ratings against grid-side power delivery requirements.

DC-link capacitors come with an expiration date which is dependent on …


Seed Modeling Of An Esd Gun Discharge To A Usb Cable, Yang Xu Jan 2021

Seed Modeling Of An Esd Gun Discharge To A Usb Cable, Yang Xu

Masters Theses

“An IC protected by a transient voltage suppression (TVS) diode may fail if the TVS device does not turn on or does not turn on quickly enough, causing the IC to take the full brunt of the electrostatic discharge (ESD) event. Transient simulation models have been developed for ESD protection devices for the purpose of system-efficient ESD design (SEED). The TVS modeling methodology has been improved to better represent the physics that occurs during the TVS response and more accurately predict the interactions between off-chip and on-chip protection devices. Moreover, a complicated test scenario -- an ESD gun discharge through …


Topological Biclustering Artmap, Raghu Yelugam Jan 2021

Topological Biclustering Artmap, Raghu Yelugam

Masters Theses

”Detection of gene mutations is central for assessing genetic factors affecting disease predisposition, genetic causes of a particular disease, and gene-targeted treatment. DNA microarray methods are widely used to detect mutations by contrasting the expression levels of thousands of genes together under varying experimental conditions. The experimental conditions could be diseased cell states compared with the normal cell states. Biclustering, a robust exploratory data analysis tool, can be applied to microarray data to detect subsets of genes that co-express highly only for a subset of experimental conditions. Such detection is crucial for gaining insights into gene regulatory networks, differential gene …


Neural Network Supervised And Reinforcement Learning For Neurological, Diagnostic, And Modeling Problems, Donald Wunsch Iii Jan 2021

Neural Network Supervised And Reinforcement Learning For Neurological, Diagnostic, And Modeling Problems, Donald Wunsch Iii

Masters Theses

“As the medical world becomes increasingly intertwined with the tech sphere, machine learning on medical datasets and mathematical models becomes an attractive application. This research looks at the predictive capabilities of neural networks and other machine learning algorithms, and assesses the validity of several feature selection strategies to reduce the negative effects of high dataset dimensionality. Our results indicate that several feature selection methods can maintain high validation and test accuracy on classification tasks, with neural networks performing best, for both single class and multi-class classification applications. This research also evaluates a proof-of-concept application of a deep-Q-learning network (DQN) to …


Axial Performance Of Self-Consolidating Concrete-Filled Fiber Tubes, Joshua David Carter Jan 2021

Axial Performance Of Self-Consolidating Concrete-Filled Fiber Tubes, Joshua David Carter

Masters Theses

"Concrete filled fiber tubes can be used to increase ductility and strength of a concrete member and self-consolidating concrete is an ideal material to use in practical applications of concrete-filled fiber tubular columns. However, the propensity of self-consolidating concrete to autogenous shrinkage could reduce the effectiveness of the concrete confinement. This research investigates the use of self-consolidating concrete in pre-cast FRP tubes and various methods of shrinkage reduction and compensation to increase the axial performance of said self-consolidating concrete-filled fiber tubes. Axial compression tests were performed under monotonic and cyclic conditions to determine the stress-strain relationship of the self-consolidating concrete …


Factors Affecting Covid-19 Pandemic, Linrui Han Jan 2021

Factors Affecting Covid-19 Pandemic, Linrui Han

Masters Theses

“COVID-19 has affected our daily lives in many aspects, such as work, healthcare, education, business, and social. With the quick spread of this new coronavirus, many countries quickly fell into a pandemic control and management mode. It has been more than one year since the discovery of COVID-19, but until now, COVID-19 is still affecting our lives and our daily operations. The research consists of two papers focusing on different factors affecting the COVID-19 pandemic. The first paper studies the effect of ICT and healthcare expenditures on the COVID-19 management and control. The second paper focuses on the impact of …


A Systematic Analysis Of Eye-Tracking Metrics For Sleepiness, Debasis Roy Jan 2021

A Systematic Analysis Of Eye-Tracking Metrics For Sleepiness, Debasis Roy

Masters Theses

”Sleepiness or sleep deprivation is a serious hazard that can be life-threatening in carrying out certain tasks (e.g., when driving or executing attention-critical tasks). Eye movement can provide cues on sleepiness. Hence, eye-tracking metrics have the potential to detect sleepiness.

In this research, we used a systematic analysis approach to identify eye-tracking metrics for sleepiness. We used several databases to identify independent experimental studies that have used eye-tracking metrics to assess sleepiness. We identified 25 studies that included 674 participants where the participants’ data were captured both in an alert state and in a sleep-deprived state. In the analysis, we …


A Meta-Analysis: Gamification In Education, Yalin Wang Jan 2021

A Meta-Analysis: Gamification In Education, Yalin Wang

Masters Theses

“Gamification has been used in a variety of contexts including education. In order to understand the effects of gamification in education, a meta-analysis was conducted. A bottom-up approach was used to analyze the effects of game design elements on learning outcomes found in the literature search. The result suggests that gamification can enhance student learning outcomes. Elements such as points, leaderboards, competitions, progress bars, feedback, and collaboration have medium to large effect sizes. Gamification also has larger effects on young children in elementary education than learners at other education levels. The study offers suggestions and guidelines for educators on the …


An International Study Of Interobserver Variability Of “String Sign” Of Pancreatic Cysts Among Experienced Endosonographers, Seifeldin Hakim, Emmanuel Coronel, Graciela M Nogueras González, Philip S Ge, Suresh T Chari, Nirav Thosani, Srinivas Ramireddy, Ricardo Badillo, Tomas Davee, Marc F Catalano, Robert J Sealock, Sreeram Parupudi, Lyndon V Hernandez, Virendra Joshi, Atsushi Irisawa, Surinder Rana, Sundeep Lakhtakia, Peter Vilmann, Adrian Saftoiu, Siyu Sun, Marc Giovannini, Matthew H Katz, Michael P Kim, Manoop S Bhutani Jan 2021

An International Study Of Interobserver Variability Of “String Sign” Of Pancreatic Cysts Among Experienced Endosonographers, Seifeldin Hakim, Emmanuel Coronel, Graciela M Nogueras González, Philip S Ge, Suresh T Chari, Nirav Thosani, Srinivas Ramireddy, Ricardo Badillo, Tomas Davee, Marc F Catalano, Robert J Sealock, Sreeram Parupudi, Lyndon V Hernandez, Virendra Joshi, Atsushi Irisawa, Surinder Rana, Sundeep Lakhtakia, Peter Vilmann, Adrian Saftoiu, Siyu Sun, Marc Giovannini, Matthew H Katz, Michael P Kim, Manoop S Bhutani

Faculty, Staff and Students Publications

BACKGROUND AND OBJECTIVES: No single optimal test reliably determines the pancreatic cyst subtype. Following EUS-FNA, the "string sign" test can differentiate mucinous from nonmucinous cysts. However, the interobserver variability of string sign results has not been studied.

METHODS: An experienced endosonographer performed EUS-FNA of pancreatic cysts on different patients and was recorded on video performing the string sign test for each. The videos were shared internationally with 14 experienced endosonographers, with a survey for each video: "Is the string sign positive?" and "If the string sign is positive, what is the length of the formed string?" Also asked "What is …


Meta-Analysis Comparing Outcomes Of Catheter Ablation For Ventricular Arrhythmia In Ischemic Versus Nonischemic Cardiomyopathy, Indranill Basu-Ray, Dibbendhu Khanra, Sumit K Shah, Anindya Mukherjee, Sudhanva V Char, Bhavna Jain, T Jared Bunch, Michael Gold, Adedayo A Adeboye, Mohammad Saeed Jan 2021

Meta-Analysis Comparing Outcomes Of Catheter Ablation For Ventricular Arrhythmia In Ischemic Versus Nonischemic Cardiomyopathy, Indranill Basu-Ray, Dibbendhu Khanra, Sumit K Shah, Anindya Mukherjee, Sudhanva V Char, Bhavna Jain, T Jared Bunch, Michael Gold, Adedayo A Adeboye, Mohammad Saeed

Faculty, Staff and Students Publications

BACKGROUND: Catheter ablation is an effective treatment for ventricular arrhythmia (VA) in ischemic cardiomyopathy (ICM). However, results in non-ICM (NICM) patients are not satisfactory, and studies comparing differences between NICM and ICM are limited. We conducted a meta-analysis of procedural characteristics and long-term outcomes of catheter ablation for VA, comparing results between ICM and NICM.

METHODS: Studies in the PubMed, EMBASE, and Cochrane databases were systematically reviewed. Four studies reporting comparison of catheter ablation of VA between ICM and NICM were examined. The Newcastle-Ottawa Scale was used to appraise study quality. A random-effects model with inverse variance method was used …


Conundra Of The Berne Convention Concept Of The Country Of Origin, Jane C. Ginsburg Jan 2021

Conundra Of The Berne Convention Concept Of The Country Of Origin, Jane C. Ginsburg

Faculty Scholarship

This essay explores one of the most important, but occasionally intractable, issues under the Berne Convention, the concept of Country of Origin. Article 5(4) of that treaty defines a work’s country of origin, but leaves out several situations, leaving those who interpret and apply the treaty without guidance in ascertaining the country of origin. I will call those situations the “Conundra of the country of origin,” and will explore two of them here. First, what is the country of origin of an unpublished work whose authors are nationals of different countries? Second, what is the country of origin of a …


Investigating The Contract Production Process, Stephen J. Choi, Robert E. Scott, G. Mitu Gulati Jan 2021

Investigating The Contract Production Process, Stephen J. Choi, Robert E. Scott, G. Mitu Gulati

Faculty Scholarship

Contract law and theory have traditionally paid little attention to the processes by which contracts are made. Instead, contracts among sophisticated parties are assumed to be full articulations of the desires of the parties; whatever the process, the outcome is the same. This article compares sovereign debt contracts from US and UK firms, with different production processes, that are trying to do the same thing under very similar legal regimes. We find that that the production process likely matters quite a bit to the final form that contracts take.


Conduction Disorders In The Setting Of Acute Stemi, Kjell Nikus, Yochai Birnbaum, Miquel Fiol-Sala, Jani Rankinen, Antoni Bayés De Luna Jan 2021

Conduction Disorders In The Setting Of Acute Stemi, Kjell Nikus, Yochai Birnbaum, Miquel Fiol-Sala, Jani Rankinen, Antoni Bayés De Luna

Faculty, Staff and Students Publications

ST-elevation myocardial (STEMI) is frequently associated with conduction disorders. Regional myocardial ischemia or injury may affect the cardiac conduction system at various locations, and neural reflexes or changes in the balance of the autonomous nervous system may be involved. Sinoatrial and atrioventricular blocks are more frequent in inferior than anterior STEMI, while new left anterior fascicular block and right bundle branch block indicate proximal occlusion of the left anterior descending coronary artery. New left bundle branch block is associated with multi-vessel disease. Most conduction disorders associated with STEMI are reversible with reperfusion therapy, but they may still impair prognosis because …


Legal Internalism In Modern Histories Of Copyright, Shyamkrishna Balganesh, Taisu Zhang Jan 2021

Legal Internalism In Modern Histories Of Copyright, Shyamkrishna Balganesh, Taisu Zhang

Faculty Scholarship

Legal internalism refers to the internal point of view that professional participants in a legal practice develop toward it. It represents a behavioral phenomenon wherein such participants treat the domain of law (or a subset of it) as normative, epistemologically self-contained, and logically coherent on its own terms regardless of whether the law actually embodies those characteristics. Thus understood, legal internalism remains an important characteristic of all modern legal systems. In this Review, we examine three recent interdisciplinary histories of copyright law to showcase the working of legal internalism. We argue that while their interdisciplinary emphasis adds to the conversation …


The Future Of International Commercial Arbitration, George A. Bermann Jan 2021

The Future Of International Commercial Arbitration, George A. Bermann

Faculty Scholarship

Although international commercial arbitration is not subject to as much criticism as investor-State arbitration, it is nonetheless facing challenges going forward. These challenges are several, and only some can be addressed in this chapter. Some relate to concerns that have been with international arbitration for a long time. These include costs, delay and excessive formality, as well as arbitrator neutrality. Others – arbitration ethics, diversity, and transparency – are not new, but are taking on greater urgency. Still others simply represent new developments more or less extrinsic to international arbitration but with which international arbitration must cope. Among these changes …


Deep Simulation Of Facial Appearance Changes Following Craniomaxillofacial Bony Movements In Orthognathic Surgical Planning, Lei Ma, Daeseung Kim, Chunfeng Lian, Deqiang Xiao, Tianshu Kuang, Qin Liu, Yankun Lang, Hannah H Deng, Jaime Gateno, Ye Wu, Erkun Yang, Michael A K Liebschner, James J Xia, Pew-Thian Yap Jan 2021

Deep Simulation Of Facial Appearance Changes Following Craniomaxillofacial Bony Movements In Orthognathic Surgical Planning, Lei Ma, Daeseung Kim, Chunfeng Lian, Deqiang Xiao, Tianshu Kuang, Qin Liu, Yankun Lang, Hannah H Deng, Jaime Gateno, Ye Wu, Erkun Yang, Michael A K Liebschner, James J Xia, Pew-Thian Yap

Faculty, Staff and Students Publications

Facial appearance changes with the movements of bony segments in orthognathic surgery of patients with craniomaxillofacial (CMF) deformities. Conventional bio-mechanical methods, such as finite element modeling (FEM), for simulating such changes, are labor intensive and computationally expensive, preventing them from being used in clinical settings. To overcome these limitations, we propose a deep learning framework to predict post-operative facial changes. Specifically, FC-Net, a facial appearance change simulation network, is developed to predict the point displacement vectors associated with a facial point cloud. FC-Net learns the point displacements of a pre-operative facial point cloud from the bony movement vectors between pre-operative …


The Bile Acid Induced Hepatokine Orosomucoid Suppresses Adipocyte Differentiation, Sung Ho Lee, Jong Min Choi, Sung Yun Jung, Aaron R Cox, Sean M Hartig, David D Moore, Kang Ho Kim Jan 2021

The Bile Acid Induced Hepatokine Orosomucoid Suppresses Adipocyte Differentiation, Sung Ho Lee, Jong Min Choi, Sung Yun Jung, Aaron R Cox, Sean M Hartig, David D Moore, Kang Ho Kim

Faculty, Staff and Students Publications

Bile acids have recently emerged as key metabolic hormones with beneficial impacts in multiple metabolic diseases. We previously discovered that hepatic bile acid overload distally modulates glucose and fatty acid metabolism in adipose tissues to exert anti-obesity effects. However, the detailed mechanisms that explain the salutary effects of serum bile acid elevation remain unclear. Here, proteomic profiling identified a new hepatokine, Orosomucoid (ORM) that governs liver-adipose tissue crosstalk. Hepatic ORMs were highly induced by both genetic and dietary bile acid overload. To address the direct metabolic effects of ORM, purified ORM proteins were administered during adipogenic differentiation of 3T3-L1 cells …


Propertied Rites, Kellen R. Funk Jan 2021

Propertied Rites, Kellen R. Funk

Faculty Scholarship

This Essay reviews Jack Rakove’s Beyond Belief, Beyond Conscience and Winnifred Fallers Sullivan’s Church State Corporation with an eye towards the complex management of religious property in U.S. constitutional doctrine. Part I summarizes Rakove’s book and highlights its value in the context of recent scholarship on early American legislative theory. Part II critiques Rakove’s turn from description towards advocacy of James Madison’s liberal protestant political theology. Part III summarizes Sullivan’s book as a particularly potent rebuttal to Rakove’s. Part IV takes up Sullivan’s method to consider the most recent crisis of religious property before the Supreme Court, that of government …


Automating Fairness? Artificial Intelligence In The Chinese Court, Rachel E. Stern, Benjamin L. Liebman, Margaret Roberts, Alice Z. Wang Jan 2021

Automating Fairness? Artificial Intelligence In The Chinese Court, Rachel E. Stern, Benjamin L. Liebman, Margaret Roberts, Alice Z. Wang

Faculty Scholarship

How will surging global interest in data analytics and artificial intelligence transform the day-to-day operations of courts, and what are the implications for judicial power? In the last five years, Chinese courts have come to lead the world in their efforts to deploy automated pattern analysis to monitor judges, standardize decision-making, and observe trends in society. This Article chronicles how and why Chinese courts came to embrace artificial intelligence, making public tens of millions of court judgments in the process. Although technology is certainly being used to strengthen social control and boost the legitimacy of the Chinese Communist Party, examining …


Slavery's Constitution: Rethinking The Federal Consensus, Maeve Glass Jan 2021

Slavery's Constitution: Rethinking The Federal Consensus, Maeve Glass

Faculty Scholarship

For at least half a century, scholars of the early American Constitution have noted the archival prominence of a doctrine known as the “federal consensus.” This doctrine instructed that Congress had no power to interfere with the institution of slavery in the states where it existed. Despite its ubiquity in the records, our understanding of how and why this doctrine emerged is hazy at best. Working from a conceptual map of America’s founding that features thirteen local governments coalescing into two feuding sections of North and South, commentators have tended to explain the federal consensus either as a vestige of …