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Racial Disparities In Systemic Sclerosis: Short‐ And Long‐Term Outcomes Among African American Participants Of Sls I And Ii, Elizabeth R Volkmann, Virginia Steen, Ning Li, Michael D Roth, Philip J Clements, Daniel E Furst, Shervin Assassi, Dinesh Khanna, Grace-Hyun J Kim, Jonathan Goldin, Robert M Elashoff, Donald P Tashkin

Faculty, Staff and Student Publications

OBJECTIVE: To evaluate short- and long-term outcomes of African American (AA) participants of Scleroderma Lung Studies (SLS) I and II.

METHODS: SLS I randomized 158 participants with systemic sclerosis-interstitial lung disease (SSc-ILD) to 1 year of oral cyclophosphamide (CYC) versus placebo. SLS II randomized 142 participants with SSc-ILD to 1 year of oral CYC followed by 1 year of placebo versus 2 years of mycophenolate (MMF). Joint models compared the course of forced vital capacity (FVC) and diffusing capacity for carbon monoxide (DLCO) between AA and non-AA, and Cox proportional hazard models assessed long-term morbidity and mortality outcomes.

RESULTS: In …

Restoration Of Cardiac Function After Myocardial Infarction By Long-Term Activation Of The Cns Leptin-Melanocortin System, Fabio N Gava, Alexandre A Da Silva, Xuemei Dai, Romain Harmancey, Sadia Ashraf, Ana C M Omoto, Mateus C Salgado, Sydney P Moak, Xuan Li, John E Hall, Jussara M Do Carmo

Faculty, Staff and Student Publications

Heart failure has a high mortality rate, and current therapies offer limited benefits. The authors demonstrate that activation of the central nervous system leptin-melanocortin pathway confers remarkable protection against progressive heart failure following severe myocardial infarction. The beneficial cardiac-protective actions of leptin require activation of brain melanocortin-4 receptors and elicit improvements in cardiac substrate oxidation, cardiomyocyte contractility, Ca

Mir-9-1 Suppresses Cell Proliferation And Promotes Apoptosis By Targeting Uhrf1 In Lung Cancer, Cheng-You Jia, Wei Xiang, Ji-Bin Liu, Geng-Xi Jiang, Feng Sun, Jian-Jun Wu, Xiao-Li Yang, Rui Xin, Yi Shi, Dan-Dan Zhang, Wen Li, Zavuga Zuberi, Jie Zhang, Gai-Xia Lu, Hui-Min Wang, Pei-Yao Wang, Fei Yu, Zhong-Wei Lv, Yu-Shui Ma, Da Fu

Faculty, Staff and Student Publications

Lung cancer is listed as the most common reason for cancer-related death all over the world despite diagnostic improvements and the development of chemotherapy and targeted therapies. MicroRNAs control both physiological and pathological processes including development and cancer. A microRNA-9 to 1 (miR-9 to 1) overexpression model in lung cancer cell lines was established and miR-9 to 1 was found to significantly suppress the proliferation rate in lung cancer cell lines, colony formation in vitro, and tumorigenicity in nude mice of A549 cells. Ubiquitin-like containing PHD and RING finger domains 1 (UHRF1) was then identified to direct target of miR-9 …

Piercing The Veil: Examining Demographic And Political Variables In State Foi Law Administration, A.Jay Wagner

College of Communication Faculty Research and Publications

State and local governments play an important, and growing, role in everyday lives. The exploratory study positions FOI laws as a central mechanism in providing transparency to these more proximate governments. It is premised on a FOI audit, or field experiment, of 1002 requests across 9 U.S. state laws and 334 jurisdictions. The sample represents a broad cross-section of geographic, demographic and political variables, and the study analyzes these variables predictive and correlative value in determining outcomes, timeliness and communication in FOI requests. The results suggest significance in race and political variables in FOI outcomes and processes. The study's strongest …

Table Of Contents (Vol. 92, Issue 1)

University of Colorado Law Review

No abstract provided.

Whole Designs, Sarah Burstein

University of Colorado Law Review

In the past decade, there has been a renewed interest in the concept of patentable subject matter-that is, what kinds of things can you get a patent for? But this attention has, to date, been focused on utility patents, the patents that protect how things work. There has been scant attention paid to statutory subject matter and design patents, the patents that protect how things look. These patents have gained prominence in both practice and scholarship since the $1 billion verdict in Apple v. Samsung. The time has come to take the question of design patentable subject matter seriously. Today, …

Influencing Legislation For Juveniles In The Adult Judicial System: A Phenomenological Examination Of Legal Advocates, Krista F. Franklin

Antioch University Dissertations & Theses

INFLUENCING LEGISLATION FOR JUVENILES IN THE ADULT JUDICIAL SYSTEM: A PHENOMENOLOGICAL EXAMINATION OF LEGAL ADVOCATES Krista Franklin Antioch University Seattle Seattle, WA This phenomenological study explores the lived experience of Washington State lawmakers and legal activists regarding their involvement in passing Washington State Senate Bill 5064 in February 2014. In response to the 2012 landmark federal Supreme Court decision, Miller v. Alabama, Senate Bill 5064 reduced the number of crimes for which juveniles could be sentenced as adults to life without parole. Six interviewees were selected from those who testified in Olympia, WA. Individual interviews were conducted in an open-ended …

A Survey To Assess Adhd Symptoms And Detect Feigning In Adult Adhd: Initial Scale Development, Michelle Babcock

Antioch University Dissertations & Theses

Adult attention-deficit / hyperactivity disorder (ADHD) diagnoses have significantly increased over the last 20 years, and in some cases, adults seek an ADHD diagnosis to procure stimulant medication and academic accommodations. With the ease of access to the internet, adults can acquire the knowledge to misrepresent symptoms for secondary gain. The falsification of symptoms or feigning is problematic for the individual seeking the diagnosis, the psychological profession, and society at large. This study aimed to develop a multipurpose self-report scale comprised of the DSM-5 ADHD criteria, executive functioning, and embedded symptom validity indexes to assess ADHD and detect feigned responses. …

When Knowing Is Not Enough: A Narrative Exploration Of How K-12 Teachers Make Decisions About The Transfer Of Critical Competencies From Professional Learning To Daily Practice, Nell E. Ballard-Jones

Antioch University Dissertations & Theses

School districts spend millions of dollars each year to provide training and learning to staff working in direct and indirect service to students (National Council on Teacher Quality, 2021). This financial commitment says nothing about what is even more important: the need for school employees and the systems in which we work to serve students more effectively. Despite vast allocations of time and money and presumably best intentions for better social and academic outcomes for students, very little data exist that reflect regular transfer and application of training/learning into professional practice (Nittler et al., 2015). By and large, schools and …

Examining The Relationship Between Five Factors Of Mindfulness And Parenting Stress: A Correlational Study Of New Mothers, Jessica L. Lazaro

Antioch University Dissertations & Theses

It can be tempting to want to dissociate from the stress of parenting. The implication being that the early years of parenthood are meant to simply be endured. In contrast, mindfully embracing all aspects of parenthood, including the difficult moments, may allow the appreciation of beauty, growth, and connection, which is so essential to the human experience, especially as it relates to the parent-child relationship. As the popularity of mindfulness research increases, so does the information we have about using it with parents in general, and mothers in particular. The current study explores what, if any, relationship exists between levels …

Video Meetings In A Pandemic Era: Emotional Exhaustion, Stressors, And Coping, Betty J. Johnson

Antioch University Dissertations & Theses

In the first quarter of 2020, societal upheavals related to the COVID-19 pandemic included employers’ work-from-home mandates and an almost overnight adoption of video meetings to replace in-person meetings no longer possible due to contagion fears and social distancing requirements. This exploratory study aimed to address, in part, the scientific knowledge gap about video meetings as a source of emotional labor. The study used mixed methods to explore three hypotheses concerning how the contemporary use of video meetings related to emotional exhaustion, stressors, and coping. Data were gathered through an online survey questionnaire. Emotional exhaustion, the dependent variable in the …

Dialogic Identity Construction: The Influence Of Latinx Women's Identities In Their Health Information Management Practice, Maria A. Caban Alizondo

Antioch University Dissertations & Theses

The purpose of this qualitative research was to study the experiences of Latinx women who lead in health information management in the United States. Latinx health information management professionals are faced with everchanging workplace dynamics and biases in which they are repeatedly reminded of their individual and ethnic differences that require them to construct and co-construct new facets to their identities in social contexts. By grounding this work in narrative inquiry and viewing identities critically, space is given for delving deeper into the specifics of how gender, ethnicity, culture, and class influenced Latinx women’s leadership practice. Interviews offered the opportunity …

Psychometric Development Of The Autism Trait Survey, Gwendolyn S. Barnhart

Antioch University Dissertations & Theses

There are limited tools for professionals who work with individuals with autism to ascertain individuals’ strengths and challenges within the various facets of symptomology after diagnosis. Professionals can currently use personal interviews and psychological reports to determine individuals’ strengths and challenges to determine the types of services that would benefit them following initial diagnosis. The limitations of this practice are that the levels of understanding, accuracy, and use of these measures vary in the field. Furthermore, the norms of diagnostic measures are the entire population rather than solely individuals on the autistic spectrum/autistics (IOS/A). A new measure is necessary: one …

Applying The Present To The Past: The Experiences Of Five Civil Rights Rabbis In Context Of Contemporary Leadership Theory, Bradley G. Levenberg

Antioch University Dissertations & Theses

This dissertation examines the experiences of five civil rights-era rabbis (William Silverman, Randall Falk, Alfred Goodman, Irving Bloom, and Burton Padoll) to highlight their contributions, leadership approaches, struggles, and achievements with a particular emphasis on social justice. As each of the rabbis drew from their understanding of the richness of the Jewish textual canon, the study includes a survey of Biblical, Talmudic, and contemporary Jewish sources that laid the groundwork for their rabbinic activism and which compel rabbis today. The study dramatically highlights those texts as providing applicable strategies with regard to leading a congregation with a “prophetic” voice, knowing …

Using Principles Of Seascape Ecology To Consider Relationships Between Spatial Patterning And Mobile Marine Vertebrates In A Seagrass-Mangrove Ecotone In Bimini, Bahamas, Sarah Rebecca Taylor Driscoll

Antioch University Dissertations & Theses

Seagrass meadows and mangrove forests are ecologically and economically important systems that are increasingly threatened by anthropogenic activity. This study used a non-invasive method, baited remote underwater video systems (BRUVS), to observe mobile marine vertebrates in the seagrass-mangrove ecotone in North and South Bimini, the only area where mangroves remain in the northwestern Bahamas. An extensive area of mangroves and seagrass was removed for coastal development in North Bimini, where a marine protected area, the North Bimini Marine Reserve (NBMR), has been under consideration for decades. This research applied principles of seascape ecology to assess species abundance, diversity, and richness …

The Social Impacts Of Tourism In The Unesco Champlain Adirondack Biosphere Reserve (Usa), Kelly L. Cerialo

Antioch University Dissertations & Theses

In its most benign form, tourism is able to protect the cultural and ecological integrity of a region and to promote economic development in line with sustainability principles. Additionally, sustainable forms of tourism have the potential to improve the quality of life within the host community by promoting intergenerational equity. However, sustainable models of tourism are extremely challenging to design, implement, and manage at the community level because of competing stakeholder interests. There are significant power dynamics associated with sustainable tourism planning and management that often fail to incorporate all citizens’ voices, particularly those belonging to underprivileged backgrounds. Due to …

Educating For Global Competence: Co-Constructing Outcomes In The Field: An Action Research Project, Kristina A. Van Winkle

Antioch University Dissertations & Theses

Capacity building for globally competent educators is a 21st Century imperative to address contemporary complex and constantly changing challenges. This action research project is grounded in positive psychology, positive organizational scholarship, relational cultural theory, and relational leadership practices. It sought to identify adaptive challenges educators face as they try to integrate globally competent teaching practices into their curricula, demonstrate learning and growth experienced by the educators in this project, and provide guidance and solutions to the challenges globally competent educators face. Six educators participated in this three-phase project, which included focus groups, reflective journal entries, and an exit interview. Data …

Pediatric Bullying And Victimization: Quality Improvement Project In A Primary Care Setting, Melanie Sklar

Antioch University Dissertations & Theses

Bullying is a form of aggression characterized by repeated psychological or physical oppression, which negatively impacts children. More recently, the phenomenon of cyberbullying, or electronic bullying, has become prevalent. Despite efforts by schools to address forms of bullying, young people continue to be victimized. Primary care settings are well placed to address these issues with patients and their families to improve care and outcomes. Screenings and mental health referrals by physicians have been shown to reduce future involvement in bullying and increase access to treatment. When thinking about healthcare improvements in primary care settings, screening has been shown to be …

Teachers Of Color's Perception On Identity And Academic Success: A Reflective Narrative, Lynette Suliana Sikahema Finau

Antioch University Dissertations & Theses

Research and scholarship in multicultural education has consistently affirmed that as a result of the long standing racial academic achievement gap and the current teaching force not reflecting the changing demographics of students in the United States, students of color continue to be deprived from having teachers who look like them and who may bring similar life, social, and cultural experiences that can increase the value they place on academics. The purpose of this study was to explore the lived experiences of teachers of color and how they perceive their identity as significant and meaningful to their profession and its …

Investing To Prevent: Description Of An Innovative Approach To Commissioning A Supervised Toothbrushing Programme Across Multiple Local Authorities In England, Zoe Allen, Robert Witton

Peninsula Dental School

No abstract provided.

Stroke Survivors’ Experiences And Perceptions Of Post-Stroke Fatigue Education In The Subacute Phase Of Stroke. The Fase Qualitative Study, Tremayne J Elizabeth, Jennifer Freeman, Ali Coppola

School of Health Professions

Abstract Introduction Post-stroke fatigue significantly impacts stroke survivors’ rehabilitation, morbidity and quality of life. The evidence-base of post-stroke fatigue education is scarce and inconsistently translated to practice. Research is necessary to understand the current provision, impact and perceptions of post-stroke fatigue education from the stroke survivor’s perspective. The aim of this study is to develop an understanding of stroke survivors’ current experiences and perceptions of fatigue and the role of post-stroke fatigue education in subacute stroke. Methods A United Kingdom-based qualitative inquiry using semi-structured interviews involving 10 participants who had experienced subacute stroke was conducted using thematic data analysis. Findings …

Behaviour Change Approaches For Individuals With Diabetes To Improve Foot Self-Management: A Scoping Review, Joanne Paton, Sally Abey, Phil Hendy, Jennifer Williams, Richard Collings, Lynne Callaghan

School of Health Professions

Abstract Background Diabetes related foot complications are increasing in complexity, frequency and cost. The application of self-management strategies can reduce the risk of individuals developing foot complications. The type, range and nature of the literature focusing on interventions that support patients with diabetic foot self-management is unknown. This scoping review aimed to i) identify self-management actions and risky behaviour avoidance strategies within interventions, ii) map the theoretical functions through which these behaviour change interventions have an effect, iii) display gaps in the research. Methodology Arksey and Malley’s (2003) 5 stage framework was followed to conduct the scoping study. This methodological …

A Human Rights Approach To Risk: The Case Of Human Germline Editing, Jessica Almqvist

Loyola of Los Angeles International and Comparative Law Review

No abstract provided.

Scope, Context And Quality Of Telerehabilitation Guidelines For Physical Disabilities: A Scoping Review, Krithika Anil, Jennifer A. Freeman, Sarah Buckingham, Sara Demain, Hilary Gunn, Ray B. Jones, Angela Logan, Jonathan Marsden, Diane Playford, Kim Sein, Bridie Kent

School of Health Professions

ObjectiveTo identify the available guidance and training to implement telerehabilitation movement assessments for people (adults and children) with a physical disability, including those recovering from COVID-19.DesignRapid scoping review.Included sources and articlesPubMed, CINAHL, PsychInfo, Cochrane, Embase, Web of Science, PEDro, UK Health Forum, WHO, National Archives and NHS England were searched using the participant–concept–context framework from 2015 to August 2020. Primary studies that recruited individuals with physical disabilities and guidance documents aimed at providers to implement movement-related telerehabilitation were included.Results23 articles (11 primary research studies, 3 systematic reviews and 9 guidance documents) were included out of 7857 that were identified from …

Configuring Perceived Fit To Mitigate Consumer Animosity In The Context Of Cross-Border Sport Sponsorships., Robert Angell, Paul Bottomley, Ružica Brečić, Jelena Filipović, Matthew Gorton, Maria Logkizidou, John White

Plymouth Business School

Abstract Research question: While cross-border sport sponsorships are widespread, such partnerships introduce a notable complication – consumers in one country may dislike the sponsor’s country of origin (COO). This raises the question as to whether animosity towards a sponsor’s COO negatively affects sponsorship outcomes, and if so, how it can be addressed. For the latter, we examine holistic sponsor-object fit as well as a set of its constituent elements. Research methods: Data collection pertained to a brand engaged in a hypothetical sponsorship. Study 1 involves a Serbian brand sponsoring the Croatia national football team and for Study 2 German sponsors …

Inter-Organisational Relationships For Social Impact: A Systematic Literature Review, Dariusz Siemieniako, Krzysztof Kubacki, Maciej Mitręga

Plymouth Business School

No abstract provided.

Effects Of Perioperative Oxygen Concentration On Oxidative Stress In Adult Surgical Patients: A Systematic Review, Alexander H. Oldman, Daniel S. Martin, Martin Feelisch, Michael P.W. Grocott, Andrew F. Cumpstey

Peninsula Medical School

No abstract provided.

Defining Dental Operative Skills Curricula: An Adee Consensus Paper, James Field, Jonathan Dixon, Ashley Towers, Rachel Green, Hathal Albagami, Guy Lambourn, Julie Mallinson, Wietske Fokkinga, Jorge Tricio-Pesce, Tin Crnić, Sibylle Vital

Peninsula Dental School

This paper reports on the recent activity of the pan-European consensus of the ADEE Special Interest Group for Pre-Clinical Operative Skills. Following the previous recommendations from the group, and in order to support teachers and to harmonise the delivery of skills training across Europe, a more formal curriculum relating to pre-clinical operative skills needs to be created. This paper reports European consensus surrounding the categorisation (level of importance, and difficulty) of basic operative dental clinical skills within the undergraduate curriculum and provides recommendations relating to session structure and timing of curricular elements for basic operative dental clinical skills teaching.

Identifying The Health Care–Initiated And Self-Initiated Interventions Used By Women For The Management Of Rectal Emptying Difficulty Secondary To Obstructive Defecation: A Scoping Review Protocol, Sharon Eustice, Alison James, Ruth Endacott, Bridie Kent

School of Nursing and Midwifery

No abstract provided.

Older Patients’ Views Of Oral Health Care And Factors Which Facilitate Or Obstruct Regular Access To Dental Care-Services: A Qualitative Systematic Review, Jos M. Latour, Alexander R. Legge, Mona Nasser

School of Nursing and Midwifery

No abstract provided.