Digital Commons Network^™

Drivers Of International Migration Of Doctors To And From The United Kingdom, N Brennan, N Langdon, M Bryce, T Gale, A Knapton, L Burns, N Humphries

Peninsula Medical School

No abstract provided.

Ivermectin Induces Apoptosis Of Esophageal Squamous Cell Carcinoma Via Mitochondrial Pathway, Nana Xu, Mengmeng Lu, Jiaxin Wang, Yujia Li, Xiaotian Yang, Xiajie Wei, Jiaoyang Si, Jingru Han, Xiaojuan Yao, Juanmei Zhang, Junqi Liu, Yanming Li, Hushan Yang, Dengke Bao

Department of Medical Oncology Faculty Papers

Background: Esophageal squamous cell carcinoma (ESCC) is the most predominant primary malignant tumor among worldwide, especially in China. To date, the successful treatment remains a mainly clinical challenge, it is imperative to develop successful therapeutic agents.

Methods: The anti-proliferative effect of ivermectin on ESCC is investigated in cell model and in nude mice model. Cell apoptosis was assessed using flow cytometry, TUNEL assay and western blotting. Mitochondrial dysfunction was determined by reactive oxygen species accumulation, mitochondrial membrane potential and ATP levels.

Results: Our results determined that ivermectin significantly inhibited the proliferation of ESCC cells in vitro and in vivo. Furthermore, …

Exposure To Prenatal Maternal Distress And Infant White Matter Neurodevelopment, Catherine H. Demers, Maria M. Bagonis, Khalid Al-Ali, Sarah E. Garcia, Martin A. Styner, John H. Gilmore, M. Camille Hoffman, Benjamin L. Hankin, Elysia Poggi Davis

Psychology: Faculty Scholarship

The prenatal period represents a critical time for brain growth and development. These rapid neurological advances render the fetus susceptible to various influences with life-long implications for mental health. Maternal distress signals are a dominant early life influence, contributing to birth outcomes and risk for offspring psychopathology. This prospective longitudinal study evaluated the association between prenatal maternal distress and infant white matter microstructure. Participants included a racially and socioeconomically diverse sample of 85 mother–infant dyads. Prenatal distress was assessed at 17 and 29 weeks’ gestational age (GA). Infant structural data were collected via diffusion tensor imaging (DTI) at 42–45 weeks’ …

Will My Imbalance End?, Wendy W. Tan

Publications and Research

The epidemics of violence, fatal robbery, repetitive burglaries, inflation, shortage of labor, and a variety of abnormal phenomena during the Pandemic have pressured many Americans (the author inclusive) to walk in the dark alley of fear, and consequently lost the balance of visions to the future. In this reflective article, the author describes her own frustration and how she works on ending her imbalance

A Systematic Review And Narrative Synthesis Of The Effectiveness Of Peer- Versus Faculty-Led Simulation For Clinical Skills Acquisition In Undergraduate Student Nurses., Graham Williamson, Daniel Clarke, Andrea Stebbings

School of Nursing and Midwifery

No abstract provided.

Hypothalamic Steroid Receptor Coactivator-2 Regulates Adaptations To Fasting And Overnutrition, Yongjie Yang, Yanlin He, Hailan Liu, Wenjun Zhou, Chunmei Wang, Pingwen Xu, Xing Cai, Hesong Liu, Kaifan Yu, Zhou Pei, Ilirjana Hyseni, Makoto Fukuda, Qingchun Tong, Jianming Xu, Zheng Sun, Bert W O'Malley, Yong Xu

Faculty, Staff and Students Publications

The neuroendocrine system coordinates metabolic and behavioral adaptations to fasting, including reducing energy expenditure, promoting counterregulation, and suppressing satiation and anxiety to engage refeeding. Here, we show that steroid receptor coactivator-2 (SRC-2) in pro-opiomelanocortin (POMC) neurons is a key regulator of all these responses to fasting. POMC-specific deletion of SRC-2 enhances the basal excitability of POMC neurons; mutant mice fail to efficiently suppress energy expenditure during food deprivation. SRC-2 deficiency blunts electric responses of POMC neurons to glucose fluctuations, causing impaired counterregulation. When food becomes available, these mutant mice show insufficient refeeding associated with enhanced satiation and discoordination of anxiety …

Remote Teaching In Nepalese Higher Education During Covid-19: Teachers' Perspectives, Suman Laudari, Sojen Pradhan, Sanjay Lama

Higher Learning Research Communications

Objectives: The purpose of the study was to examine the factors that supported or inhibited teacher participation in remote teaching. Teaching and learning in Nepal was predominantly face-to-face prior to the pandemic, and the previous studies showed that the use of educational technology in higher education was limited.

Method: This exploratory case study draws on data derived from focus group discussions with teachers in higher education. Thematic analysis was employed to explore the impacts of different factors in sudden transition to remote teaching.

Findings: Findings show that personal factors such as teachers’ sense of duty and their attitude towards technology …

Open Access And Education Resources (Oaer) And The Analysis Of University And Library Websites In Pakistan, Nooruddin Merchant Mr., Shahira Ishaq Ms.

Library Philosophy and Practice (e-journal)

The abrupt transition to online teaching and learning during COVID-19 has necessitated the need of providing information sources and textbooks online. The Open Access and Education Resources (OAER) have the potential to fill the gap which may have occurred due to fiscal constraints and budget cuts within Higher Education Institutions in developing countries. This study highlights the importance of OAER movement, its emergence as a strong information resource and its contribution in teaching and learning in higher education. The study also examines the current state and utilization of OAER resources in Pakistani higher education institutions. The authors have used two …

A Brief History Of Writing From The Perspective Of Restoration Scripture, Noel B. Reynolds

Faculty Publications

This paper brings together selected insights of modern epigraphers who study the languages and texts of the ancient near east to illuminate how we should understand the composition and history of central texts in the Bible and the Book of Mormon.

Vice, Virtue, And Memory: The Question Of Fairness At Nuremberg, Kiegan E. Lloyd

Culture, Society, and Praxis

No abstract provided.

"Lawcraft": China's Evolving Approach To International Law And The Implications For American National Security, Matthew H. Ormsbee

Fordham Law Review Online

No abstract provided.

Book Reviews, Florida Historical Society

Florida Historical Quarterly

TORIES, DONS, AND REBELS: THE AMERICAN REVOLUTION IN BRITISH WEST FLORIDA, by J. Barton Starr, reviewed by Aubrey C. Land; ZORA NEALE HURSTON: A LITERARY BIOGRAPHY, by Robert E. Hemenway, reviewed by Kevin M. McCarthy; THE LIVING DOCK AT PANACEA, by Jack Rudloe, reviewed by Wyatt Blassingame; FEARLESS AND FREE: THE SEMINOLE INDIAN WAR, 1835-1842, by George Walton, reviewed by Frank Laumer; AFRICANS AND SEMINOLES: FROM REMOVAL TO EMANCIPATION, by Daniel F. Littlefield, Jr., reviewed by James W. Covington; RELIGION IN THE OLD SOUTH, by Donald G. Mathews, reviewed by Walter B. Posey; ADAMS AND JEFFERSON: A REVOLUTIONARY DIALOGUE, by …

A New Guide To Sources Of Spanish Florida History, D. Lorne Mcwatters

Florida Historical Quarterly

Research into Spanish Borderlands history received major impetus from a recent National Endowment for the Humanities grant to the P. K. Yonge Library of Florida History, University of Florida, Gainesville. In August 1977, the Endowment awarded $127,000 to the Yonge Library to initiate a three-year project to prepare a guide to the Florida Borderlands collection. The Spanish Florida Borderlands Project represents the first concerted effort to organize and make these materials accessible.

Seminole Folktales, Hedvig Tetens Evans

Florida Historical Quarterly

In Florida in the early 1950s when these stories were gathered, folktales were still being kept alive among some of the oldest Seminole Indians. All of the following tales were collected at the Brighton Reservation which is located in the center of the state northwest of Lake Okeechobee. It is one of three federal Indian reservations in Florida. The Seminole words that are used are in the Muskogee (Cow Creek) dialect. This is different from the Hitchiti dialect used by the Miccosukees who live on the Tamiami Trail west of Miami.

Torment Of Pestilence: Yellow Fever Epidemics In Pensacola, George F. Pearce

Florida Historical Quarterly

For more than a century, yellow fever epidemics intermittently swept over Pensacola, Florida, producing a high mortality, disrupting its economic and social life, dividing community leaders and medical authorities over courses of action in combatting them, causing untold numbers to flee, some permanently, and keeping those who remained in a state of demoralizing terror. The approach of summer each year invariably brought with it the fear of a repetition of the dreadful experience. This atmosphere of apprehension and utter helplessness was nourished by ignorance about the origin, transmission, and prevention of the disease. It was not until 1900 that medical …

The Menendez Marquez Cattle Barony At La Chua And The Determinants Of Economic Expansion In Seventeenth-Century Florida, Amy Bushnell

Florida Historical Quarterly

Spanish Florida has the historical reputation of a bleak and unfriendly place, unproductive, impoverished, and unhealthy, where governors and soldiers, friars and passive Indian converts were unable to defend their own borders, much less make the land self-sustaining. The doleful letters from officials of the colony about the lateness or inadequacy of the garrison’s situado have made an impact on researchers, if they did not on the Crown. In recent years, however, examples of economic activity have been examined that belie this picture of total dependency. There were times during the seventeenth century when Spanish Florida approached self-sufficiency and was …

Florida History Research In Progress, Florida Historical Society

Florida Historical Quarterly

This list shows the amount and variety of Florida history research and writing currently underway, as reported to the Florida Historical Quarterly. Doctoral dissertations and masters theses completed in 1977 are included. Research in Florida history, sociology, anthropology, political science, archeology, geography, and urban studies is included.

The White Springs Post Office Caper, Jerrell H. Shofner

Florida Historical Quarterly

With the 1885 constitution ratified and the state’s poll tax law about to become effective, the 1888 election was the last in which large numbers of blacks voted and was the last in which the Republican party posed a serious threat to the predominance of the Democrats for many decades. Even then the Democrats carried the state races by comfortable majorities. But the 1888 race had been an exciting election in which some Conservative-Democrats in the black belt counties had left themselves vulnerable to charges of violating federal election laws. This caused concern among them when Democrat Grover Cleveland was …

The Ambush Of Captain John Williams, U.S.M.C.: Failure Of The East Florida Invasion, 1812-1813, J. H. Alexander

Florida Historical Quarterly

Twelve-mile Swamp lies northwest of St. Augustine between Interstate 95 and U.S. Highway 1, the old King’s Road. The heavily wooded swamp, named for its approximate distance from St. Augustine, is a forbidding area of cypress bogs and palmetto thickets. The swamp has probably changed little since 1812 when, in one violent half-hour, it became the focal point of an extraordinary, undeclared military contest between the United States and Spain.

A Free Facetious Gentleman, Jean Savy, Double Agent?, Aileen Moore Topping

Florida Historical Quarterly

The Spanish minister, Don Joseph Patino, had read other accounts of the alarming growth of the new English colony called Georgia. He recalled the Franciscan friar’s report of a conversation with an Indian chief who had been brought to England from Georgia by Mr. James Oglethorpe. The chief had stated that the English would use his people to capture San Augustin de la Florida. A French engineer who had come to Madrid to solicit payment for past service in the Indies had presented a description of present conditions in Cuba, Florida, and Carolina. He had learned in South Carolina that …

Book Reviews, Florida Historical Society

Florida Historical Quarterly

CRACKER MESSIAH: GOVERNOR SIDNEY J. CATTS OF FLORIDA, by Wayne Flynt, reviewed by Dewey W. Grantham; FLORIDA TERRITORY IN 1844: THE DIARY OF MASTER EDWARD C. ANDERSON, UNITED STATES NAVY, edited by W. Stanley Hoole, reviewed by George E. Buker; PROCEEDINGS OF THE GULF COAST HISTORY AND HUMANITIES CONFERENCE, VOLUME VI, THE CULTURAL LEGACY OF THE GULF COAST, 1870-1940, edited by Lucius F. Ellsworth and Linda V. Ellsworth, reviewed by Gloria Jahoda; GOLD, GALLEONS AND ARCHAEOLOGY: A HISTORY OF THE 1715 SPANISH PLATE FLEET AND THE TRUE STORY OF THE GREAT FLORIDA TREASURE FIND, by Robert F. Burgess and Carl …

Bernardo De Galvez's Combat Diary For The Battle Of Pensacola, 1781, Maury Baker

Florida Historical Quarterly

There are four contemporary versions, three Spanish and one English, of the events leading to the Spanish capture of English-held Pensacola, May 8, 1781. A long line of scholars have written about it, using archival sources in Spain and England. The last of them, N. Orwin Rush, in his incisive and valuable monograph, Spain’s Final Triumph Over Great Britain in the Gulf of Mexico: The Battle of Pensacola, March 9 to May 8, 1781, relied heavily upon the diary of Bernardo de Galvez, which was believed to be available only in its printed version.

Civil War Letters Of Major General James Patton Anderson, Margaret Anderson Uhler

Florida Historical Quarterly

In a time when patriotism was among the greatest of American virtues, few men pursued it more passionately than General James Patton Anderson of the Confederate army. Born in Winchester, Franklin County, Tennessee, February 16, 1822, he was the son of Margaret Adair and Colonel William Preston Anderson, a veteran of the War of 1812. His maternal grandfather was General John Adair, a hero in both the American Revolution and the War of 1812, and the eighth governor of Kentucky.

The Heavenly Planation: A Seventeenth-Century Mention Of Florida, Nancy Lee-Riffe

Florida Historical Quarterly

During England's civil war in the seventeenth century, British journalism and newspapers got their start. Legions of newssheets were written and distributed. Though some of them ran for several years and hundreds of issues, most were only short-lived ventures. The underground Royalist papers had a particularly difficult time. One of these, of which only three issues have survived, is Mercurius Aulicus (For King Charles II). A weekly published in 1649, its intent is to attack and mock the actions of the new government and to spur loyalty and support for Charles, the son of the beheaded king. In it Florida …

A Love-Mad Man: Senator Charles W. Jones Of Florida, Judy Nicholas Etemadi

Florida Historical Quarterly

Following ten years of service in the United States Senate, Charles W. Jones of Pensacola was in a strong position to serve Florida when the forty-ninth Congress convened on December 7, 1885. As an Irish immigrant, he had used his background to aid Grover Cleveland’s successful 1884 presidential campaign. A publicized trip to Ireland in the summer of 1883 and addresses to large audiences of Irish-Americans had channelled votes to the Democratic party. As a result, Jones was regarded as a leader in the party. The inauguration of a Democratic president, whose campaign he had materially assisted, vaulted Jones into …

A View Of Spanish West Florida: Selected Letters Of Governor Juan Vicente Folch, David H. White

Florida Historical Quarterly

The waning years of the eighteenth century were a time of conflict and turmoil. Europe was convulsed by the wars of the French Revolution and their repercussions were felt throughout the world, including America. The isolated frontier province of Florida, so prized by Spain because of its strategic location to the Caribbean, the Gulf of Mexico, and the Atlantic shipping routes was in an exposed position. Besides the threats from the English and the French, Spanish officials in St. Augustine and Pensacola had to be concerned with the illicit activities of privateers, particularly along the northeast coast of Florida, antagonistic …

Book Reviews, Florida Historical Society

Florida Historical Quarterly

HOPES, DREAMS, AND PROMISES: A HISTORY OF VOLUSIA COUNDY, FLORIDA, by Michael G. Schene, reviewed by Thomas Graham; THE EMERGENCE OF A CITY IN THE MODERN SOUTH: PENSACOLA, 1900-1945, by James R. McGovern, reviewed by Wayne Flynt; THE UNIVERSITY OF MIAMI: A GOLDEN ANNIVERSARY HISTORY, 1926-1976, by Charlton W. Tebeau, reviewed by Thelma Peters; THE SOUND OF BELLS: THE EPISCOPAL CHURCH IN SOUTH FLORIDA, 1892-1969, by Joseph D. Cushman, Jr., reviewed by Samuel S. Hill, Jr.; CONFUSION TO THE ENEMY: A BIOGRAPHY OF EDWARD BALL, by Raymond K. Mason and Virginia Harrison, reviewed by William M. Goza; THE FLEDGLING PROVINCE: …

Turmoil At Big Cypress: Seminole Deer And The Florida Cattle Tick Controversy, Kenneth R. Philip

Florida Historical Quarterly

Indian Commissioner John Collier and Secretary of the Interior Harold L. Ickes, who was accompanied by his wife and son, left Washington, D.C., during the early spring of 1935 to meet with representatives of approximately 600 Seminole Indians who lived on three reservations and on scattered plots of land in Florida. Their purpose was to honor the one-hundredth anniversary of the beginning of the Second Seminole War and to conclude an informal peace treaty with these native Americans. After their arrival at West Palm Beach on March 18, Commissioner Collier requested that officials from the Dania Seminole Agency take them …

Contents Of Volume Lv, Florida Historical Society

Florida Historical Quarterly

No abstract provided.

Book Reviews, Florida Historical Society

Florida Historical Quarterly

LEMON CITY: PIONEERING ON BISCAYNE BAY, 1850-1925, by Thelma Peters, reviewed by John D. Pennekamp; EIGHTEENTH-CENTURY FLORIDA: LIFE ON THE FRONTIER, edited by Samuel Proctor, reviewed by J. Leitch Wright, Jr.; PRESENCIA HISPANICA EN LA FLORIDA, AYER Y HOY: 1513-1976, edited by José Augustín Balseire, reviewed by Bruce S. Chappell; PARADE OF MEMORIES: A HISTORY OF CLAY COUNTY, FLORIDA, by Arch Frederic Blakey, reviewed by George E. Buker; SPAIN: FORGOTTEN ALLY OF THE AMERICAN REVOLUTION, by Buchanan Parker Thomson, reviewed by Aileen Moore Topping; THE IMPACT OF THE AMERICAN REVOLUTION ABROAD: PAPERS PRESENTED AT THE FOURTH SYMPOSIUM, MAY 8 AND …