Digital Commons Network^™

Farnesol Secretion As A Possible Driving Force For Maintaining Candida Albicans As A Diploid, Kenneth Nickerson, Cory Boone, Kory Parker

Kenneth Nickerson Papers

Candida albicans is a pathogenic dimorphic fungus which is invariably found as a diploid in patients. C. albicans secretes the sesquiterpene farnesol both as a quorum sensing molecule which blocks the yeast to hypha conversion and as a virulence factor for pathogenicity. 20-25 μM farnesol kills other competing yeasts and fungi, often by triggering apoptosis, and yet wild type diploid C. albicans tolerates 300-500 μM farnesol. The recent availability of 10 haploid strains of C. albicans (5 mating type aand 5 mating type α) allowed us to compare their production of and sensitivity to farnesol. On average, the heterozygous diploid …

Task Classification During Visual Search Using Classic Machine Learning And Deep Learning, Devangi Vilas Chinchankar

Master's Projects

In an average human life, the eyes not only passively scan visual scenes, but most times end up actively performing tasks including, but not limited to, searching, comparing, and counting. As a result of the advances in technology, we are observing a boost in the average screen time. Humans are now looking at an increasing number of screens and in turn images and videos. Understanding what scene a user is looking at and what type of visual task is being performed can be useful in developing intelligent user interfaces, and in virtual reality and augmented reality devices. In this research, …

The Impact Of Programming Language’S Type On Probabilistic Machine Learning Models, Sherif Elsaid

Master's Projects

Software development is an expensive and difficult process. Mistakes can be easily made, and without extensive review process, those mistakes can make it to the production code and may have unintended disastrous consequences.

This is why various automated code review services have arisen in the recent years. From AWS’s CodeGuro and Microsoft’s Code Analysis to more integrated code assistants, like IntelliCode and auto completion tools. All of which are designed to help and assist the developers with their work and help catch overlooked bugs.

Thanks to recent advances in machine learning, these services have grown tremen- dously in sophistication to …

An Examination Of Bone Loss During Space Travel With Differential Gene Expression Analysis, Claudia Vo

Master's Projects

Spaceflight poses many risks to human health due to the harsh conditions of microgravity, cosmic radiation, and confinement. One of the impacts that spaceflight entails is bone loss, which is a risk to astronauts as future space missions will require long travel durations. To elucidate the role of genetics in spaceflight bone loss, in this study differential gene expression analysis was performed using Nextflow-RCP, an adaptation of NASA Genelab’s RNA-Seq Consensus pipeline. The dataset for this project was GLDS-241, which contained samples from mice femoral skin. To gain a comprehensive understanding of the genes involved in bone loss, the results …

Mrna-Sequencing Pipeline For Differential Gene Expression Analysis, Crystal Han

Master's Projects

Endothelial cells (ECs) line the insides of blood vessels and play a key role in the coagulation and vascular repair system. Under normal circumstances, ECs are constantly expressing anticoagulants to prevent clots and maintain healthy blood flow. But when there is an injury to the vessel, endothelial cells become centrally involved in orchestrating the complex series of events that would lead to the clotting of the wound. Thus, ECs are dynamic and respond accordingly based on changes in their local environment. Unfortunately, endothelial cells can sometimes misinterpret cues from the environment and initiate coagulation when there is no vessel damage …

Effective Cancer Detection Using Higher-Order Genome Architecture And Chromatin Interactions, My Chung

Master's Projects

Cancer is a complex disease which requires interactions between cell-intrinsic alterations and tumor microenvironment. The connection between epigenetics and genomic structure plays a key role in chromatin interaction which promotes enhancer-promoter interactions for transcriptional activities. Alterations of chromatin states in oncogenic signaling pathway potentially cause cancer cell-intrinsic changes and inappropriate instructions to normal cell cycles, leading to abnormal cell growth. Resulting phenotypic changes are correlated to underlying changes in higher-order chromatin structure such as topologically associating domains (TADs) and compartments. In cancer cells, TAD structure is usually altered to facilitate the communication between enhancers and promoters in addition to higher …

Fasting Status Of Steller Sea Lion Pups, Stephanie G. Crawford

Biological Sciences

Following population declines in species of concern, wildlife managers often seek to identify underlying causes to understand and predict population dynamics for better future management. Often, physiological and/or behavioral metrics are measurable markers of decline, and these are often detectable well before declines are measurable through population surveys. During the 1970's, 80's, and 90's Steller sea lion (SSL; Eumetopias jubatus) populations in the western portion of their breeding range declined by ~85%. Though declines in most regions have since stabilized or exhibited modest recovery, some subpopulations breeding in the Aleutian Islands continue to decline. In contrast, SSL subpopulations in eastern …

Establishing Program Standards To Meet The Needs Of Postsecondary Trade And Industrial Education, Beno Rubin, Michael F. Kosloski Jr., Roberto Loya

Journal of Research in Technical Careers

The focus of this study was to develop standards that can be used for establishing and assessing high-quality postsecondary trade and industrial programs. A four-round Delphi technique was used to generate consensus regarding program standards. The panel of experts, comprised of postsecondary administrators of trade and industrial programs, was used to determine which program standards should guide the development and assessment of high-quality trade and industrial education programs. The result was a list of 17 standards and descriptions. The standards included Academic Integration, Advisory Committee, Curriculum, Employer Feedback, Faculty Qualifications, Meaningful Employment, Placement Rates, Program Design, Program Review, Safety, Soft …

Developing A Structured Ojt Program: The Case Of A Small Manufacturing Company In A Rural Region, Raymond A. Dixon Ph.D.

Journal of Research in Technical Careers

This study explored the process followed by a small manufacturing company in a rural area to implement a planned training program to develop the technical skills of its engineering/production workers as the company expands its operation. A case study design was used. Data was collected over an eight-month period by the examination of documents, direct observation, and interview. Findings indicate the process followed were consistent with elements of the Talent Development Architecture. The growth of the company presents learning opportunities for both the owner and his management team. The job analysis provided inputs to implement a planned training program and …

Systems And Methods For Scalable Retinal Screening Programs, Jeremy Richard Benson

Computer Science ETDs

This dissertation addresses gaps in artificial intelligence-based computer vision tasks in the medical image processing field. We demonstrate effective methods for standardizing and augmenting digital fundus photographs so that robust convolutional neural network-based systems can perform high-throughput disease classification and generalize to never-before-seen data from novel camera technologies, scaling with the changing hardware landscape, as well as keeping up with vast amount of incoming data from the ever-increasing population. We also tackle the problem of discovering relevant samples in an unlabeled cohort of image data, thus widening the bottleneck to all downstream supervised machine learning tasks.

Conceptual Design Of Two Tiltrotor Aircraft For Urban Air Mobility, Michael T. Radotich

Engineering

There has been an abundance of new and novel aircraft designs created for Urban Air Mobility (UAM) in recent years. The National Aeronautics and Space Administration (NASA) contributes to the research and development of this industry in part by applying its aircraft design tools to create conceptual designs of UAM reference vehicles. The vehicles are intended to quantify the tradeoffs and performance capabilities necessary for VTOL (vertical takeoff and landing) aircraft in the UAM design space. The reference vehicles represent a variety of configurations that seek to encompass many of the design characteristics suitable for UAM. This thesis focuses on …

“The New Pinkertons”: Anti-Union Consultants And Surveillance Tech Thwart Organizing, Jo Constantz

Capstones

In 2020, just 6.3% of U.S. private-sector workers were union members, despite the fact that 68% of Americans approve of labor unions, the highest since 1965, and nearly half of non-union workers say they would join.

After World War II, wage growth kept pace with GDP growth, but then began to diverge in the 1970s, according to a study by the RAND Corporation. After 1975, incomes of the bottom 90% rose more slowly than the economy as a whole, while incomes of the top 10% grew faster. The declining wage growth coincided with and is closely related to a drop-off …

Improving First Case Starts For A Neurosurgery Or, Tara L. Goodall

Master's Projects and Capstones

Problem: On-time first cases for operating rooms (OR) is a worldwide focus for improvement. OR delays have many adverse effects, including economic costs and patient and facility staff satisfaction.

Context: The site for this improvement project is a medium-sized hospital in Northern California. There are 12 ORs, with an average of 600-700 cases. Neurosurgery was the chosen specialty due to low on-time starts and long delay minutes. The focus was working with one OR to improve first case on-time starts by 20%.

Interventions: A worksheet was created to track room setup, delay reasons, and delay minutes. A visual setup guide …

Improving An Electrocardiogram Competency Assessment Tool For Registered Nurses, Laurel K. Ng

Master's Projects and Capstones

Abstract

Problem: Rapid and accurate interpretation of an EKG rhythm is an advanced-level competency required for all acute care nurses working in a cardiac monitored/telemetry unit. Observational data collected over a 4-month period by the facility clinical nurse educators identified that less than half of the nurses required to take the EKG exam passed on the first attempt.

Context: The education department at the facility onboards approximately 550-600 nurses annually for the 241-bed community hospital in the San Francisco Bay Area of Northern California, part of a larger healthcare organization.

Interventions: A total of 19 nurses from various …

Increasing Lactation Consultant Support To The Mch Unit, Daniella Grace Mcclendon

Master's Projects and Capstones

Problem: Breastfeeding is the most beneficial feeding choice for newborns and one of the best ways for mothers to bond with their newborns. In the current Maternal Child Health (MCH) unit, exclusive breastfeeding rates have fallen lower than the unit’s goal of 82%.

Context: Exclusive breastfeeding, when a newborn consumes only human breastmilk, is not always an easy process to initiate immediately after birth and in the early postpartum period. On this specific unit, there is not enough lactation consultant support to provide all patients on the unit.

Interventions: This project considers adding additional lactation consultants to support the MCH …

Improving Medication Administration Safety In A Correctional Facility With An Electronic Medication Administration System, Rosalinda Salazar

Master's Projects and Capstones

Problem: According to the World Health Organization (2020), medication errors are one of the leading causes of injury and avoidable harm in health care globally.

Context: The county jail houses approximately 700 inmates/patients on a daily basis, and the potential for error when administering medications is high as medications are prepared manually using a paper medication administration record.

Interventions: The jail began using an electronic health record/barcode administration system on October 19, 2020.

Measures: Unusual occurrence reports related to medication errors were reviewed. The time frame included 6 months before electronic implementation, and 6 months after implementation.

Results: Unusual occurrence …

Multicultural Music Education: Preparedness, Perceptions, And Practice Among Virginia Elementary Music Educators, Benjamin J. Luna

Masters Theses, 2020-current

Benjamin Joel Luna, M. M.

James Madison University, 2021

Supervisor: Lisa M. Maynard

The purpose of this study was to examine the Multicultural Music Education (MME) practices of established (i.e. more than three years of music teaching experience) Elementary Music Teachers in the state of Virginia by examining their responses to a series of survey questions specific to the topic. Participants (N=18) were all current Elementary Music Teachers in the state of Virginia with more than three years of experience.

Participants were asked to use Likert-scale ratings for the majority of the questions but were also given the …

Targeting Nstemi Readmissions: Education To Protect The Hearts Of Our Patients, Gisha Gireesan

Master's Projects and Capstones

Section I: Abstract

Problem: January and February 2021 data showed a rise in readmissions for the NSTEMI population. This is significant as 2020 had a readmission rate of 5.6% and 7.3% in 2019. This sudden increase in readmissions within the first two months of the year is a cause for concern and immediate action is needed.

Context: 2020 had a reduction in cardiac catheterizations due to the multiple canceled cases during the COVID 19 pandemic. As the cases were being rescheduled along with new cases in 2021, the institution experienced an uptake in readmissions.

Interventions: The staff of department 220 …

Decreasing Patient Fall Rates In The Microsystem, Kevin Dwayne Sanchez Camaya

Master's Projects and Capstones

Abstract

Problem: Falls are considered never events, yet continuously occur in the inpatient setting. Falls,

especially falls with injuries, impact the patients, the staff, and the hospital. Falls cause extended lengths of stay, affect the morale of the patients and the staff, and are non-reimbursable events.

Context: There have been an increased rate of falls within a medical/surgical/telemetry unit

microsystem at a Northern California hospital despite standardized screening and prevention tools. The unit can house up to 52 patients and is the designated Covid unit of the hospital at the time of this project.

Interventions: The interventions include optimizing the …

Patient Coordinated Care Response Team, Joshua Fox

Master's Projects and Capstones

Section I: Abstract

Problem: Communication between medical professionals and patients is a critical element to patient satisfaction and safety. The 2020 patient overall satisfaction scores for the local Roseville hospital were 73%. These data demonstrated an opportunity to enhance processes and the culture at the local Roseville hospital to meet the communication needs of its patient population.

Context: A patient coordinated care response team was developed to improve communication for newly diagnosed cancer patients or other life-altering diagnosis patients.

Interventions: A survey was completed to establish the current state of patient satisfaction with communication practices with healthcare providers in the …

Enhanced Recovery After Surgery: Effectiveness Of Real Time Data Tracking Tools, Alatia S. Jentons

Master's Projects and Capstones

Enhanced Recovery after Surgery (ERAS) has been proven by evidence to lower both recovery time and postoperative complication rates while also being cost-effective. It is a new recovery process that consists of several bundles in order to meet adherence. The hospital site where this project was conducted was at a Northern California Medical Center which provides care for in-patient postoperative, urgent and non-urgent cases. On our assigned units, we identified the potential for improvement after observing a lack of standardization of real-time charting for ERAS. This resulted in retro data, which is not an effective way to collect data when …

Post Cesarean Surgical Site Infection Reduction Through Vaginal Preparation, Jennifer M. Jaime

Master's Projects and Capstones

Abstract

Problem: The increasing rates of surgical site infections (SSIs) after cesarean delivery have a negative impact on patient morbidity, mortality, postoperative fevers, trauma, and hospital costs.

Context: Interventions are a necessity for this population however, there is lack of preventative practice utilized in the labor and delivery unit to reduce the rates of post cesarean SSIs.

Interventions: The preventative evidenced based practice of vaginal preparation with 10% povidone-iodine was implemented on women in the operating room before their cesarean procedure. Educational materials such as informative presentations, videos, and posters were created to educate nursing staff on the implementation of …

Reducing Maternal Falls On A Postpartum Unit Through Staff Education, Kathleen Benjamin

Master's Projects and Capstones

There have been 23 documented falls on the maternity unit at Hospital A over the past three years. This fall rate is above the national average, making the reduction of falls on the postpartum unit a priority to maintain the hospital’s Magnet status and improve patient safety. Data analysis related to contributing factors of falls and staff education on best ambulation practices has the potential to decrease the number of maternal falls on the targeted microsystem population of the postpartum unit. This quality improvement project conducted a fall audit on each documented fall case, performed an environmental survey of the …

Coyote Management In San Francisco, Matthew Greer

Master's Projects and Capstones

As cities in North America grow, coyotes have become progressively more important species in urban ecosystems. Moreover, as coyotes increasingly use these urban spaces, human-coyote conflicts have become more common, creating a need for new management strategies. This paper will explore how the city of San Francisco could create a new coyote management plan for its highly visible coyote population. San Francisco has had a persistent coyote population since the early 2000s (Todd, 2018). Currently, the coyote population is close to 100 individuals and is still growing (J. Young, Presidio Trust, pers. comm.). To explore this topic a literature review …

Improving Medical-Surgical Nurses’ Confidence In Initiating The Code Blue Process, Moung Sui A. Lee

Master's Projects and Capstones

Lack of confidence in responding to codes can decrease patient outcomes, for any delay in care reduces the chances of revival. As codes occur less frequently in medical-surgical units, nurses who work in this specialty are not as equipped to respond to codes like their ICU or ER colleagues. To address this concern, a code blue readiness training was implemented in six different medical-surgical units of an East Bay hospital. Pre and post surveys were utilized for data comparison on nurses’ confidence in responding to various steps of a code. The results revealed an overall increase in confidence. For this …

Oral Care Experiences Of Palliative Care Patients, Their Relatives/Carers And Healthcare Professionals: A Qualitative Systematic Review, Delgado M Bernardes, Anastasios Plessas, Lorna Burns, Helen Neilens, Sarah Griffiths, Jos Latour

Peninsula Dental School

No abstract provided.

In The Matter Of: Marva Gorham

All Decisions

HPD terminated Section 8 subsidy due to "criminal activity" in 2017, and failure to provide documents to HPD. Tenant provided evidence of guilty plea/probationary sentence, successful drug rehab, and submitted documents prior to this hearing. Hearing officer found HPD's decision was mostly incorrect, reversed it, and reinstated the subsidy.

Riding The Wave Of Information: Library Professionals’ Opinion Towards Information Literacy (Il) Program In Academic Libraries Of Pakistan, Shahzadi Humbhi, Munazza Jabeen, Shabbir Tareen, Alia Humbhi

Library Philosophy and Practice (e-journal)

The present study investigated status, strategies to promote the IL programs, contribution of social media, and challenges to provide IL programs in the academic libraries of Pakistan. A concurrent mixed-method technique was used and a structured questionnaire was designed to collect the data and in-depth interviews from 12 academic librarians of the capital cities of four provinces of Pakistan. A systematic sampling technique was used to collect the data from library professionals. The results reveal that academic libraries took imitative to launch IL programs at academic libraries of Pakistan but there is a need for improvement and revamp them. The …

Distribution, Abundance And Natural Enemies Of The Invasive Tomato Leafminer, Tuta Absoluta (Meyrick) In Kenya, G. Kinyanjui, F. M. Khamis, F. L.O. Ombura, E. U. Kenya, S. Ekesi, S. A. Mohamed

All Peer-Reviewed Publications

Tuta absoluta (Meyrick) has become a serious menace to sustainable production of tomato in Kenya. A survey was conducted between April 2015 and June 2016 to determine its distribution, abundance, infestation, and damage levels on tomato, and associated natural enemies. Trap counts of T. absoluta moths were recorded in all surveyed 29 counties, which indicated its nationwide distribution irrespective of altitude. Tuta absoluta was present in both open fields and greenhouses. The highest moth/trap/day was 115.38 ± 15.90. Highest leaf infestation was 92.22% and the highest number of mines and larvae per leaf were 3.71 ± 0.28 and 2.16 ± …

Epa Region 8 Qa Document Review Crosswalk, Nikia Greene

Silver Bow Creek/Butte Area Superfund Site

No abstract provided.