Digital Commons Network^™

Spotlight On Unwto Elibrary, Dr.S. Nirubasethukumari, Dr.A. Thirumagal, Dr.M. Mani

Library Philosophy and Practice (e-journal)

Over the decades, tourism has experienced continued growth and deepening diversification to become one of the fastest growing economic sectors in the world. Modern tourism is closely linked to development and encompasses a growing number of destinations.(Lew, Hall, & Williams, 2004) This paper analyses the origin and features of United Nations World Tourism Organization (UNWTO) like building a consortium and its UNWTO elibrary facilities like its publications which includes, ebooks, e journals, World Tourism barometers and dashboards. In addition to 500 free documents on current tourism trends, large number of publications on the impact of Covid 19 on global tourism …

Public Health Insurance And Pharmaceutical Innovation: Evidence From China, Xuan Zhang, Huihua Nie

Research Collection School Of Economics

Developing countries are characterized by low levels of pharmaceutical innovation. A likely reason is their small market size, which is not because of the population size but because of low levels of income and lack of health insurance coverage. This study exploits a natural experiment from the implementation of a public health insurance program for rural residents in China (New Cooperative Medical Scheme [NCMS]) to examine whether the pharmaceutical industry increases innovation regarding diseases covered by the NCMS that are prevalent in rural areas. We examine the 1993–2009 patent data to gauge pharmaceutical innovation in China. Diseases with a 10% …

Joint Tests For Dynamic And Spatial Effects In Short Dynamic Panel Data Models With Fixed Effects And Heteroskedasticity, Zhenlin Yang

Research Collection School Of Economics

Simple and reliable tests are proposed for testing the existence of dynamic and/or spatial effects in fixed-effects panel data models with small T and possibly heteroskedastic errors. The tests are constructed based on the adjusted quasi scores (AQS), which correct the conditional quasi scores given the initial differences to account for the effect of initial values. To improve the finite sample performance, standardized AQS tests are also derived, which are shown to have much improved finite sample properties. All the proposed tests are robust against nonnormality, but some are not robust against cross-sectional heteroskedasticity (CH). A different type of adjustments …

Generalized Jump Regressions For Local Moments, Tim Bollerslev, Jia Li, Leonardo Salim Saker Chaves

Research Collection School Of Economics

We develop new high-frequency-based inference procedures for analyzing the relationship between jumps in instantaneous moments of stochastic processes. The estimation consists of two steps: the nonparametric determination of the jumps as differences in local averages, followed by a minimum-distance type estimation of the parameters of interest under general loss functions that include both least-square and more robust quantile regressions as special cases. The resulting asymptotic distribution of the estimator, derived under an infill asymptotic setting, is highly nonstandard and generally not mixed normal. In addition, we establish the validity of a novel bootstrap algorithm for making feasible inference including bias-correction. …

Retirement Preparedness In Singapore, Junxing Chay, Seonghoon Kim

Research Collection School Of Economics

This chapter presents empirical evidence on a variety of measures to assess the social and economic well-being of near-retirees and retirees in Singapore based on rich data from the Singapore Life Panel, a nationally representative monthly panel survey of 50- to 70-year-old adults in Singapore. Large differences in retirement behaviour and household financial conditions related to retirement preparedness across education and wealth groups are documented. This suggests the importance of a retirement-related policy that focuses on the low-skilled and low-wealth groups. In addition, we discuss and evaluate current public policy designed to increase the employment of older workers and propose …

The Coaches’ Eye: Exploring Coach Decision-Making During Talent Identification, Alexandra Hannah Roberts

Theses: Doctorates and Masters

For decades, researchers and practitioners interested in talent identification have discussed the coaches’ eye: the elusive ability that allows some coaches to ‘see’ qualities in an athlete that point to their talent or future potential. While there is significant anecdotal evidence of coaches who possess this ability, there is little empirical research supporting the validity or reliability of the coaches’ eye. Guided by ecological dynamics, this thesis employs mixed methodologies to explore the decision-making that underpins how high-level coaches identify talent in Olympic combat sports. These four studies captured the processes of thirty- four coaches during the talent identification process, …

Siblings Of People With Intellectual Disability: Relationships And Decision-Making Across The Life Span, Wendy Simpson

Theses: Doctorates and Masters

A growing amount of research focuses on siblings of children with disabilities. However, limited evidence exists to provide a solid understanding and depth of knowledge of the issues that affect adult sibling relationships when one has intellectual disability. Since sibling relationships are the longest lasting family relationship, they are becoming more important because people with disability are outliving their parents or main caregivers. The increased longevity of people with disability has a societal and economic impact that has been recognised in the context of the recently introduced National Disability Insurance Scheme (NDIS) in Australia. By exploring the experiences of siblings …

Towards An Evidence-Informed Differentiated Learning Consolidation Process To Support Classroom Instruction, Nicola Carr-White

Theses: Doctorates and Masters

Despite many years of teaching experience, the differentiation and consolidation of classroom learning presented challenges for the researcher. In response, a Differentiated Learning Consolidation Process (DLCP) was developed through informal classroom-based action research over several years. Using low cost and accessible resources, it developed into a manageable supplementary intervention to support individual student needs and the retention of classroom instruction. Increasing interest from colleagues led the researcher to provide professional development on the instructional design and implementation of the DLCP. Through this experience, it became apparent that the DLCP theoretical assumptions were largely unknown. The current study was pursued to …

Tasteful Piano Performance In Classic-Era Britain, James Huntingford

Theses: Doctorates and Masters

In recent decades, British solo piano repertoire of the Classic era has attracted increasing interest from researchers. A number of scholars have sought to identify the compositional elements that comprise late eighteenth- and early nineteenth-century British piano music. Despite this interest, there has been little research into the conventions of performance with which this repertoire is inextricably associated. Moreover, scant attention has been given to the notions of taste that are so often encountered in contemporaneous music treatises and philosophical writings. This thesis addresses these gaps in the existing literature by examining tasteful piano performance in late eighteenth- and early …

Creative Constraints: Developing A Method For Restrictive Jazz Composition, Harry Mitchell

Theses: Doctorates and Masters

This research aimed to develop a method of jazz composition that utilises data-based restrictions to facilitate the composition process. An analysis rating tool (ART) was developed based on methodologies created by Aaron Stroessner and Jan LaRue to extract elements of melody, harmony, rhythm and form from compositions on Seamus Blake’s album Bellwether and Will Vinson’s album Stockholm Syndrome. The ART then facilitated a practice-led composition process in which the data from the analysis were used as the primary source of creativity to generate and record a set of 10 compositions. Through an iterative process of composing with and refining the …

A Defensive Strategy For Detecting Targeted Adversarial Poisoning Attacks In Machine Learning Trained Malware Detection Models, Adrian Michael Wood

Theses: Doctorates and Masters

Machine learning is a subset of Artificial Intelligence which is utilised in a variety of different fields to increase productivity, reduce overheads, and simplify the work process through training machines to automatically perform a task. Machine learning has been implemented in many different fields such as medical science, information technology, finance, and cyber security. Machine learning algorithms build models which identify patterns within data, which when applied to new data, can map the input to an output with a high degree of accuracy. To build the machine learning model, a dataset comprised of appropriate examples is divided into training and …

Bully Me: A Graphic Novel; The Return: A Graphic Novel; Comakademix: A Comics Anthology; Leadbetter: A Comic; Laundry: A Minicomic -And- The Erotics Of Comics: An Exegesis, Bruce Roberts Mutard

Theses: Doctorates and Masters

Beholding a comic is ideally, a pleasure. The work informs, entertains and stimulates the mind in some way. There is no gainsaying which works will affect which beholders howsoever it does, yet the expecta­tion of pleasure from a work of comics makes behold­ers seek it. Making the comic is also a pleasure, even if the process can be long-winded, winding and dif­ficult. The maker wants to give others the same plea­sure they drew from beholding comics, but in their way, making their vision of Batman, Lieutenant Blue­berry or, their own story worlds. What this research seeks to explain are many …

3d Dental Biometrics: Automatic Pose-Invariant Dental Arch Extraction And Matching, Xin Zhong, Zhiyuan Zhang

Research Collection School Of Computing and Information Systems

A novel automatic pose-invariant dental arch extraction and matching framework is developed for 3D dental identification using laser-scanned dental plasters. In our previous attempt [1-5], 3D point-based algorithms have been developed and they have shown a few advantages over existing 2D dental identifications. This study is a continuous effort in developing arch-based algorithms to extract and match dental arch feature in an automatic and pose-invariant way. As best as we know, this is the first attempt at automatic dental arch extraction and matching for 3D dental identification. A Radial Ray Algorithm (RRA) is proposed by projecting dental arch shape from …

Sheep And Goat Industry Funding Scheme Annual Report 2019/2020, Department Of Primary Industries And Regional Development, Western Australia

Biosecurity published reports

The Sheep and Goat Industry Funding Scheme (IFS) has been operating since 2010 to address biosecurity threats relevant to the Western Australian (WA) sheep and goat industry. The Scheme was established by regulation under the Biosecurity and Agriculture Management Act 2007 to enable sheep and goat producers to identify pest and disease priorities at a whole-of-industry level and raise funds for activities to address these priorities.

There are currently three Industry Funding Schemes in operation. In addition to the Sheep and Goat IFS, there is a Cattle IFS and a Grains, Seeds and Hay IFS. The three IFSs operate in …

Coherence And Identity Learning For Arbitrary-Length Face Video Generation, Shuquan Ye, Chu Han, Jiaying Lin, Guoqiang Han, Shengfeng He

Research Collection School Of Computing and Information Systems

Face synthesis is an interesting yet challenging task in computer vision. It is even much harder to generate a portrait video than a single image. In this paper, we propose a novel video generation framework for synthesizing arbitrary-length face videos without any face exemplar or landmark. To overcome the synthesis ambiguity of face video, we propose a divide-and-conquer strategy to separately address the video face synthesis problem from two aspects, face identity synthesis and rearrangement. To this end, we design a cascaded network which contains three components, Identity-aware GAN (IA-GAN), Face Coherence Network, and Interpolation Network. IA-GAN is proposed to …

Clinicopathologic Implications Of Complement Genetic Variants In Kidney Transplantation, Zhen Ren, Stephen J Perkins, Latisha Love-Gregory, John P Atkinson, Anuja Java

2020-Current year OA Pubs

Genetic testing has uncovered rare variants in complement proteins associated with thrombotic microangiopathy (TMA) and C3 glomerulopathy (C3G). Approximately 50% are classified as variants of uncertain significance (VUS). Clinical risk assessment of patients carrying a VUS remains challenging primarily due to a lack of functional information, especially in the context of multiple confounding factors in the setting of kidney transplantation. Our objective was to evaluate the clinicopathologic significance of genetic variants in TMA and C3G in a kidney transplant cohort. We used whole exome next-generation sequencing to analyze complement genes in 76 patients, comprising 60 patients with a TMA and …

Health Disparities And Treatment Approaches In Portopulmonary Hypertension And Idiopathic Pulmonary Arterial Hypertension: An Analysis Of The Pulmonary Hypertension Association Registry, Hilary M Dubrock, Murali Chakinala, Et Al.

2020-Current year OA Pubs

Compared to idiopathic pulmonary arterial hypertension (IPAH), patients with portopulmonary hypertension (POPH) have worse survival. Health disparities may contribute to these differences but have not been studied. We sought to compare socioeconomic factors in patients with POPH and IPAH and to determine whether socioeconomic status and/or POPH diagnosis were associated with treatment and health-care utilization. We performed a cross-sectional study of adults enrolled in the Pulmonary Hypertension Association Registry. Patients with IPAH (n = 344) and POPH (n = 57) were compared. Compared with IPAH, patients with POPH were less likely to be college graduates (19.6% vs. 34.9%, p = …

Does Circulating Progesterone Mediate The Associations Of Single Nucleotide Polymorphisms In Progesterone Receptor (Pgr)-Related Genes With Mammographic Breast Density In Premenopausal Women?, Favour A Akinjiyan, Yunan Han, Jingqin Luo, Adetunji T Toriola

2020-Current year OA Pubs

UNLABELLED: Progesterone is a proliferative hormone in the breast but the associations of genetic variations in progesterone-regulated pathways with mammographic breast density (MD) in premenopausal women and whether these associations are mediated through circulating progesterone are not clearly defined. We, therefore, investigated these associations in 364 premenopausal women with a median age of 44 years. We sequenced 179 progesterone receptor (PGR)-related single nucleotide polymorphisms (SNPs). We measured volumetric percent density (VPD) and non-dense volume (NDV) using Volpara. Linear regression models were fit on circulating progesterone or VPD/NDV separately. We performed mediation analysis to evaluate whether the effect of a SNP …

Effective Connectivity Extracts Clinically Relevant Prognostic Information From Resting State Activity In Stroke, Mohit H Adhikari, Joseph Griffis, Joshua S Siegel, Michel Thiebaut De Schotten, Gustavo Deco, Andrea Instabato, Matthieu Gilson, Maurizio Corbetta

2020-Current year OA Pubs

Recent resting-state functional MRI studies in stroke patients have identified two robust biomarkers of acute brain dysfunction: a reduction of inter-hemispheric functional connectivity between homotopic regions of the same network, and an abnormal increase of ipsi-lesional functional connectivity between task-negative and task-positive resting-state networks. Whole-brain computational modelling studies, at the individual subject level, using undirected effective connectivity derived from empirically measured functional connectivity, have shown a reduction of measures of integration and segregation in stroke as compared to healthy brains. Here we employ a novel method, first, to infer whole-brain directional effective connectivity from zero-lagged and lagged covariance matrices, then, …

Smaller Spared Subcortical Nuclei Are Associated With Worse Post-Stroke Sensorimotor Outcomes In 28 Cohorts Worldwide, Sook-Lei Liew, Catherine E Lang, Anup K Bhattacharya, Et Al.

2020-Current year OA Pubs

Up to two-thirds of stroke survivors experience persistent sensorimotor impairments. Recovery relies on the integrity of spared brain areas to compensate for damaged tissue. Deep grey matter structures play a critical role in the control and regulation of sensorimotor circuits. The goal of this work is to identify associations between volumes of spared subcortical nuclei and sensorimotor behaviour at different timepoints after stroke. We pooled high-resolution T

Perceived Barriers To Assessing Understanding And Appreciation Of Informed Consent In Clinical Trials: A Mixed-Method Study, Erin D Solomon, Jessica Mozersky, Kari Baldwin, Matthew P Wroblewski, Meredith V Parsons, Melody Goodman, James M Dubois

2020-Current year OA Pubs

INTRODUCTION: Participants and research professionals often overestimate how well participants understand and appreciate consent information for clinical trials, and experts often vary in their determinations of participant's capacity to consent to research. Past research has developed and validated instruments designed to assess participant understanding and appreciation, but the frequency with which they are utilized is unknown.

METHODS: We administered a survey to clinical researchers working with older adults or those at risk of cognitive impairment (

RESULTS: We found that using a validated assessment of consent is relatively uncommon, being used by only 44% of researchers who had an opportunity. …

A Genetic Mouse Model With Postnatal Nf1 And P53 Loss Recapitulates The Histology And Transcriptome Of Human Malignant Peripheral Nerve Sheath Tumor, Akira Inoue, Laura J Janke, Brian L Gudenas, Hongjian Jin, Yiping Fan, Joshua Paré, Michael R Clay, Paul A Northcott, Angela C Hirbe, Xinwei Cao

2020-Current year OA Pubs

BACKGROUND: Malignant peripheral nerve sheath tumors (MPNST) are aggressive sarcomas. Somatic inactivation of

METHODS: We combined 2 genetically modified alleles, an

RESULTS: Postnatal

CONCLUSIONS: The NP-Plp model recapitulates human MPNST genetically, histologically, and molecularly.

A Phase Ii Study Of Laser Interstitial Thermal Therapy Combined With Doxorubicin In Patients With Recurrent Glioblastoma, Omar H Butt, Alice Y Zhou, Jiayi Huang, William A Leidig, Alice E Silberstein, Milan G Chheda, Tanner M Johanns, George Ansstas, Jingxia Liu, Grayson Talcott, Ruth Nakiwala, Joshua S Shimony, Albert H Kim, Eric C Leuthardt, Jian L Campian, Et Al.

2020-Current year OA Pubs

BACKGROUND: The blood-brain barrier (BBB) is a major limiting factor for drug delivery in brain tumors. Laser interstitial thermal therapy (LITT) disrupts the peritumoral BBB. In this study, we examine survival in patients with recurrent glioblastoma (GBM) treated with LITT followed by low-dose doxorubicin, a potent anti-neoplastic drug with poor BBB permeability.

METHODS: Forty-one patients with recurrent GBM were enrolled; thirty patients were evaluable. Participants underwent LITT followed by 6 weekly doxorubicin treatments starting within one week (Early Arm) or at 6-8 weeks (Late Arm) after LITT. The overall survival (OS), local progression-free survival (PFS), and any PFS were compared …

The Next Generation Of Ocular Pathogen Detection, Sharon L. Sabapathypillai, Hayley R. James, Rachael R. L. Lyerla, Lynn Hassman

2020-Current year OA Pubs

Metagenomic next-generation sequencing is a powerful method for pathogen detection that combines advanced genome sequencing technology with cutting-edge bioinformatics to analyze microbial populations. Metagenomic next-generation sequencing has the potential to identify uncommon, unculturable, and even previously unidentified pathogens from a clinical isolate. Of particular interest to ophthalmology, this robust data extraction can occur from very small volume clinical samples. Here we discuss the opportunities and limitations of this technique and their current and future application to ophthalmic diagnostics.

Gene Therapy Potential For Genetic Disorders Of Surfactant Dysfunction, Ashley L Cooney, Jennifer A Wambach, Patrick L Sinn, Paul B Mccray

2020-Current year OA Pubs

Pulmonary surfactant is critically important to prevent atelectasis by lowering the surface tension of the alveolar lining liquid. While respiratory distress syndrome (RDS) is common in premature infants, severe RDS in term and late preterm infants suggests an underlying genetic etiology. Pathogenic variants in the genes encoding key components of pulmonary surfactant including surfactant protein B (SP-B,

Climate Change And Antibiotic Resistance: A Deadly Combination, Jason P Burnham

2020-Current year OA Pubs

Climate change is driven primarily by humanity's use of fossil fuels and the resultant greenhouse gases from their combustion. The effects of climate change on human health are myriad and becomingly increasingly severe as the pace of climate change accelerates. One relatively underreported intersection between health and climate change is that of infections, particularly antibiotic-resistant infections. In this perspective review, the aspects of climate change that have already, will, and could possibly impact the proliferation and dissemination of antibiotic resistance are discussed.

When Authenticity Goes Missing: How Monocultural Children’S Literature Is Silencing The Voices And Contributing To Invisibility Of Children From Minority Backgrounds, Helen Adam

Research outputs 2014 to 2021

The importance of recognising, valuing and respecting a child’s family, culture, language and values is central to socially just education and is increasingly articulated in educational policy worldwide. Inclusive children’s literature can support children’s human rights and contribute to equitable and socially just outcomes for all children. However, evidence suggests many educational settings provide monocultural book collections which are counterproductive to principles of diversity and social justice. Further, that educators’ understandings and beliefs about diversity can contribute to inequitable provision and use of diverse books and to inequitable outcomes of book sharing for many children. This paper reports on a …

To Dine In Or Not To Dine In: A Comparison Of Food Selection And Preparation Behaviours In Those With And Without Food Security, Lucy M. Butcher, Therese A. O’Sullivan, Maria M. Ryan, Johnny Lo, Julie Nyanjom, Hugh C. Wilkins, Amanda Devine

Research outputs 2014 to 2021

© 2020 The Authors. Health Promotion Journal of Australia published by John Wiley & Sons Australia, Ltd on behalf of Australian Health Promotion Association Issue addressed: Vulnerable populations are disproportionately affected by food insecurity, resulting in heightened risk of suboptimal dietary intake. Food insecure people appear to implement several coping strategies and dietary compromises to avoid hunger. Less explored in the literature is how these strategies impact consumption of food inside and outside of the home. Methods: An online survey was completed by adults (n = 1292) residing in one of five Australian states. The questionnaire comprised of the six-item …

Employees’ Perceptions Of Corporate Social Responsibility And Ethical Leadership: Are They Uniquely Related To Turnover Intention?, Mehran Nejati, Michael E. Brown, Azadeh Shafaei, Pi-Shen Seet

Research outputs 2014 to 2021

© 2020, Emerald Publishing Limited. Purpose: The purpose of this study is to investigate the simultaneous effect of ethical leadership (EL) and corporate social responsibility (CSR) on employees’ turnover intention and examine the mediating mechanism in these relationships. Design/methodology/approach: The authors conducted a field study of 851 employees across a variety of industries. This study applied partial least squares structural equation modelling for hypothesis testing. Findings: The results show that employees’ perceptions of CSR as well as EL are both uniquely and negatively related to turnover intention. The authors also found that employees’ job satisfaction but not commitment, mediates these …

What Is The Literacy Supportive Role Of The School Librarian In The United Kingdom?, Margaret K. Merga

Research outputs 2014 to 2021

© The Author(s) 2020. Building students’ literacy skills is a key educative purpose of contemporary schooling. While libraries can play a key role in fostering literacy and related reading engagement in schools, more needs to be known about school librarians’ role in promoting these goals. To this end, this article seeks to identify the nature and scope of the literacy supportive role required of the school librarian in the United Kingdom. It also investigates how this aspect is situated within the broader competing role requirements of the profession. Using a hybrid approach to content analysis including both qualitative and quantitative …