Open Access. Powered by Scholars. Published by Universities.®

Digital Commons Network™

Open Access. Powered by Scholars. Published by Universities.®

2021

Discipline
Institution
Keyword
Publication
Publication Type
File Type

Articles 56311 - 56340 of 59803

Full-Text Articles in Entire DC Network

ความสัมพันธ์ระหว่างการเปิดรับข่าวสาร การรับรู้ ทัศนคติ และพฤติกรรมทางเพศที่พึงประสงค์ของนักเรียนมัธยมศึกษาตอนปลาย, นรกมล กองสุข Jan 2021

ความสัมพันธ์ระหว่างการเปิดรับข่าวสาร การรับรู้ ทัศนคติ และพฤติกรรมทางเพศที่พึงประสงค์ของนักเรียนมัธยมศึกษาตอนปลาย, นรกมล กองสุข

Chulalongkorn University Theses and Dissertations (Chula ETD)

การวิจัยครั้งนี้มีวัตถุประสงค์ 1) เพื่อศึกษาระดับการเปิดรับข่าวสาร การรับรู้ ทัศนคติ และพฤติกรรมทางเพศที่พึงประสงค์ของนักเรียนมัธยมศึกษาตอนปลาย 2) เพื่อศึกษาความสัมพันธ์ระหว่างปัจจัยลักษณะทั่วไปของประชากรกับระดับการเปิดรับข่าวสาร การรับรู้ ทัศนคติ และพฤติกรรมทางเพศที่พึงประสงค์ของนักเรียนมัธยมศึกษาตอนปลาย และ 3) เพื่อศึกษาความสัมพันธ์ระหว่างการเปิดรับข่าวสาร การรับรู้ และทัศนคติกับพฤติกรรมทางเพศที่พึงประสงค์ของนักเรียนมัธยมศึกษาตอนปลาย กลุ่มตัวอย่างเป็นนักเรียนมัธยมศึกษาปีที่ 4-6 จำนวน 450 คน ที่ได้จากการสุ่มหลายขั้นตอน เครื่องมือที่ใช้ในการวิจัย คือ แบบสอบถามออนไลน์ วิเคราะห์ข้อมูลโดยใช้การแจกแจงความถี่ ร้อยละ ค่าเฉลี่ย และส่วนเบี่ยงเบนมาตรฐาน การทดสอบไคสแควร์ และสถิติสัมประสิทธิ์สหสัมพันธ์เพียร์สัน ผลการวิจัยพบว่า 1)กลุ่มตัวอย่างมีการเปิดรับข่าวสารและการรับรู้อยู่ในระดับน้อย ส่วนทัศนคติและพฤติกรรมทางเพศที่พึงประสงค์อยู่ในมาก 2) ความสัมพันธ์กับปัจจัยลักษณะทั่วไป การเปิดรับข่าวสารมีความสัมพันธ์กับปัจจัยด้านระดับชั้นและปัจจัยด้านอายุ การรับรู้มีความสัมพันธ์กับปัจจัยด้านเพศและปัจจัยด้านอายุ ทัศนคติมีความสัมพันธ์กับปัจจัยด้านเพศและปัจจัยด้านอายุ และพฤติกรรมทางเพศที่พึงประสงค์มีความสัมพันธ์กับปัจจัยด้านระดับชั้นและปัจจัยด้านอายุ 3) ความสัมพันธ์ระหว่างพฤติกรรมทางเพศที่พึงประสงค์ พบว่า การเปิดรับข่าวสารมีระดับความสัมพันธ์ทางลบอยู่ในระดับต่ำ (r = -0.16) การรับรู้ไม่มีความสัมพันธ์ และทัศนคติมีระดับความสัมพันธ์ทางบวกอยู่ในระดับต่ำ (r = 0.31)


Business Week Program, March 22-25, 2021, Illinois State University, College Of Business Jan 2021

Business Week Program, March 22-25, 2021, Illinois State University, College Of Business

Business Week

No abstract provided.


Electric Roller Blades, Nathan Burk, Joshua Hatch Jan 2021

Electric Roller Blades, Nathan Burk, Joshua Hatch

Electrical and Computer Engineering

Electric Roller Blades are designed to allow for fast and convenient transportation!

  • The hope for the electric roller blades is to give college students and others walking through their city a way to quickly get from point A to B. Electric Skateboards and One Wheels are heavy and bulky. The Electric Roller Blades are meant to be a less cumbersome electric vehicle. As the majority of the time users will not be commuting, the electric roller blades are more convenient then One Wheels as they can be attached to a backpack.
  • People traveling from one destination to another frequently, as …


Public Library-Based Social Work Field Placements: Guidance For Public Libraries Planning To Become A Social Work Practicum Site, Elizabeth A. Wahler, Jacob D. Ressler, Sarah C. Johnson, Colleen Rortvedt, Tasha Saecker, John Helling, Michael A. Williams, Danielle Hoover Jan 2021

Public Library-Based Social Work Field Placements: Guidance For Public Libraries Planning To Become A Social Work Practicum Site, Elizabeth A. Wahler, Jacob D. Ressler, Sarah C. Johnson, Colleen Rortvedt, Tasha Saecker, John Helling, Michael A. Williams, Danielle Hoover

Publications and Research

Public libraries are increasingly faced with patron psychosocial needs, including mental health problems, substance use, homelessness, or poverty-related needs. Since library staff are often not trained to address these needs, many are choosing to host on-site social work practicum students to provide information and referrals for patrons presenting with psychosocial needs. However, little existing guidance is available about initiating a social work practicum placement, which can leave libraries unprepared and often “reinventing the wheel”. This manuscript provides guidance on the steps that should be considered by libraries intending to host their first social work practicum student.


The Effect Of Support Systems On Delinquency, Elizabeth S. Bohrer Jan 2021

The Effect Of Support Systems On Delinquency, Elizabeth S. Bohrer

Undergraduate Honors Thesis Projects

There are many reasons why adolescents and young adults turn to delinquent behaviors, much of which result from the environment they are residing in. Copious research has been done on the effects that parent, teacher, peer, and partner relationships have on delinquency, but very little focuses on support systems as a whole. Support systems create positive or negative modeling behaviors for people to follow and individuals will allow these models to influence their own personal behavior patterns. The goal of this study is to assess how a possible change in support systems affects delinquent tendencies in a study group of …


Tracking The Racial Validity Of Placement By Probability, Annie M. Del Principe, Lesley Broder, Lauren Levesque Jan 2021

Tracking The Racial Validity Of Placement By Probability, Annie M. Del Principe, Lesley Broder, Lauren Levesque

Publications and Research

Any placement decision is a gamble on the validity of the mech- anism used. The better the placement mechanism matches the actual pro- ficiencies required for success in a future, real-life context, the more accu- rately it will place students into the best classes for them and the more valid it will prove to be. But what happens if the most obvious, commonsensical approaches to placement that would appear to have the strongest validity— writing tests for placement into writing classes—prove unreliable? Rather than accurately placing students into the “right” class for them, we now know that writing placement tests …


Stress And Coping Among Surgery Residents In A Developing Country, Qamar Riaz, Syeda Kausar Ali, Muhammad Rizwan Khan, Abdul Rehman Alvi Jan 2021

Stress And Coping Among Surgery Residents In A Developing Country, Qamar Riaz, Syeda Kausar Ali, Muhammad Rizwan Khan, Abdul Rehman Alvi

Department for Educational Development

Objective: Stress during residency training in surgical disciplines not only hampers professional development but can also compromise patient care and personal health. The purpose of this study was to measure the stress level among the surgical residents, identify factors within the learning and work environment that cause stress, and identify different strategies that the residents use habitually to cope with these stresses.
Methodology: This mix method study was conducted in the department of Surgery at Aga Khan University, Pakistan. Residents' stress level was measured using Perceived Stress Scale (PSS); focus group discussions (FGDs) with faculty and residents explored stressors during …


Evaluating The Effectiveness Of 'Mcq Development Workshop Using Cognitive Model Framework: A Pre-Post Study, Rahila Ali, Amber Shahmim Sultan, Nida Zahid Jan 2021

Evaluating The Effectiveness Of 'Mcq Development Workshop Using Cognitive Model Framework: A Pre-Post Study, Rahila Ali, Amber Shahmim Sultan, Nida Zahid

Department for Educational Development

A workshop on MCQ development using cognitive model framework was conducted for health educators from Aga Khan University (AKU) and other academic institutions. The aim was to develop the skill of preparing MCQs for assessing higher cognitive levels. A pre-post study was conducted, participant satisfaction was evaluated and pre-post test scores were used to assess learning capability of the workshop participants. Out of the 19 who attended the workshop, 16 participated in the pre- and post-tests and were included in the study through convenience sampling. The total duration of the study was six months. There was a significant difference in …


Graduate Nurse Transition Programs Pivotal Point Of Participants’ Practice Readiness Questioned During The Covid-19 Pandemic Crisis: A Scoping Review, Kylie Russell, Dianne Juliff Jan 2021

Graduate Nurse Transition Programs Pivotal Point Of Participants’ Practice Readiness Questioned During The Covid-19 Pandemic Crisis: A Scoping Review, Kylie Russell, Dianne Juliff

Nursing Papers and Journal Articles

Background: The COVID-19 pandemic requires an accessible, practice-ready nursing workforce to assist with the increase in health service delivery. Graduate nurse transition programs are the entry point for most graduates into professional practice, and this review focused on both empirical studies and gray literature to identify at what point practice readiness occurs and what can assist graduate nurses’ transition to become practice ready.

Method: A scoping review was conducted using the Joanna Briggs Institute scoping review framework.

Results: Consensus purports supportive environments, ideally in formal structured graduate transition to practice programs, to enhance graduate nurses’ clinical skills and confidence development. …


Coronary 18f-Sodium Fluoride Pet Detects High-Risk Plaque Features On Optical Coherence Tomography And Ct-Angiography In Patients With Acute Coronary Syndrome, Kamran Majeed, Jamie W. Bellinge, Steele C. Butcher, Richard Alcock, Jon Spiro, David Playford, Graham S. Hillis, David E. Newby, Trevor A. Mori, Roslyn Francis, Carl J. Schultz Jan 2021

Coronary 18f-Sodium Fluoride Pet Detects High-Risk Plaque Features On Optical Coherence Tomography And Ct-Angiography In Patients With Acute Coronary Syndrome, Kamran Majeed, Jamie W. Bellinge, Steele C. Butcher, Richard Alcock, Jon Spiro, David Playford, Graham S. Hillis, David E. Newby, Trevor A. Mori, Roslyn Francis, Carl J. Schultz

Medical Papers and Journal Articles

Background and aims: 18F-Sodium Fluoride Positron Emission Tomography (18F–NaF PET) non-invasively detects micro-calcification activity, the earliest stage of atherosclerotic arterial calcification. We studied the association between coronary 18F–NaF uptake and high-risk plaque features on intra-coronary optical coherence tomography (OCT) and CT-angiography (CTCA) and the potential application to patient-level risk stratification.

Methods: Sixty-two prospectively recruited patients with acute coronary syndrome (ACS) underwent multi-vessel OCT, 18F–NaF PET and CTCA. The maximum tissue to background ratio (TBRmax = standardised uptake value (SUV)max/SUVbloodpool) was measured in each coronary segment on 18F–NaF PET scans. High-risk plaque features on OCT …


Could "The Wonder Equation" Help Us To Be More Ethical? A Personal Reflection, Margaret Somerville Jan 2021

Could "The Wonder Equation" Help Us To Be More Ethical? A Personal Reflection, Margaret Somerville

Medical Papers and Journal Articles

This is a personal reflection on what I have learnt as an academic, researching, teaching and participating in the public square in Bioethics for over four decades. I describe a helix metaphor for understanding the evolution of values and the current “culture wars” between “progressive” and “conservative” values adherents, the uncertainty people’s “mixed values packages” engender, and disagreement in prioritizing individual rights and the “common good”. I propose, as a way forward, that individual and collective experiences of “amazement, wonder and awe” have the power to enrich our lives, help us to find meaning and sometimes to bridge the secular/ …


Essentials Of A New Clinical Practice Guidance On Familial Hypercholesterolaemia For Physicians, Gerald F. Watts, David R. Sullivan, David L. Hare, Karam M. Kostner, Ari E. Horton, Damon A. Bell, Tom Brett, Ronald J. Trent, Nicola K. Poplawski, Andrew Martin, Shubha Srinivasan, Robert N. Justo, Clara K. Chow, Jing Pang Jan 2021

Essentials Of A New Clinical Practice Guidance On Familial Hypercholesterolaemia For Physicians, Gerald F. Watts, David R. Sullivan, David L. Hare, Karam M. Kostner, Ari E. Horton, Damon A. Bell, Tom Brett, Ronald J. Trent, Nicola K. Poplawski, Andrew Martin, Shubha Srinivasan, Robert N. Justo, Clara K. Chow, Jing Pang

Medical Papers and Journal Articles

Familial hypercholesterolaemia (FH) is a common, heritable and preventable cause of premature coronary artery disease. New clinical practice recommendations are presented to assist practitioners in enhancing the care of all patients with FH. Core recommendations are made on the detection, diagnosis, assessment and management of adults, children and adolescents with FH. Management is under-pinned by the precepts of risk stratification, adherence to healthy lifestyles, treatment of non-cholesterol risk factors and appropriate use of low-density lipoprotein (LDL)-cholesterol-lowering therapies including statins, ezetimibe and proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibitors. The recommendations need to be utilised using judicious clinical judgement and shared …


Transfer Learning Artificial Intelligence For Automated Detection Of Atrial Fibrillation In Patients Undergoing Evaluation For Suspected Obstructive Sleep Apnoea: A Feasibility Study, Nestor Gahungu, Afsin Shariar, David Playford, Christopher Judkins, Eli Gabbay Jan 2021

Transfer Learning Artificial Intelligence For Automated Detection Of Atrial Fibrillation In Patients Undergoing Evaluation For Suspected Obstructive Sleep Apnoea: A Feasibility Study, Nestor Gahungu, Afsin Shariar, David Playford, Christopher Judkins, Eli Gabbay

Medical Papers and Journal Articles

Background: Individuals with obstructive sleep apnoea (OSA) experience a higher burden of atrial fibrillation (AF) than the general population, and many cases of AF remain undetected. We tested the feasibility of an artificial intelligence (AI) approach to opportunistic detection of AF from single-lead electrocardiograms (ECGs) which are routinely recorded during in-laboratory polysomnographic sleep studies.

Methods: Using transfer learning, an existing ECG AI model was applied to 1839 single-lead ECG traces recorded during in-laboratory sleep studies without any training of the algorithm. Manual review of all traces was performed by two trained clinicians who were blinded to each other's review. Discrepancies …


Supporting Families Of Patients With Dementia At End-Of-Life In Hospital, Felicity Moon, Fiona Mcdermott, David Kissane Jan 2021

Supporting Families Of Patients With Dementia At End-Of-Life In Hospital, Felicity Moon, Fiona Mcdermott, David Kissane

Medical Papers and Journal Articles

Introduction: There are barriers to implementing person-and family-centred end-of-life care for people with dementia in hospitals. Nursing care for people with dementia is enhanced through family involvement. However, families report unmet needs during admissions contributing to distress and dissatisfaction. Furthermore, little is known about families’ needs during end-of-life care for people with dementia in hospital.

Aim: This study examined perceptions of interpersonal care during end-of-life for patients with dementia.

Methods: This research used a qualitative approach framed through a social constructionist and complex systems theoretical frameworks. Hospital clinicians (n = 20) and bereaved family members (n = 12) of deceased …


The Impact Of Device-Assisted Therapies On The Gut Microbiome In Parkinson's Disease, Michal Lubomski, Xiangnan Xu, Andrew J. Holmes, Jean Y.H. Yang, Carolyn M. Sue, Ryan L. Davis Jan 2021

The Impact Of Device-Assisted Therapies On The Gut Microbiome In Parkinson's Disease, Michal Lubomski, Xiangnan Xu, Andrew J. Holmes, Jean Y.H. Yang, Carolyn M. Sue, Ryan L. Davis

Medical Papers and Journal Articles

Background: Microbiome feedbacks are proposed to influence Parkinson’s disease (PD) pathophysiology. A number of studies have evaluated the impact of oral medication on the gut microbiome (GM) in PD. However, the influence of PD device-assisted therapies (DATs) on the GM remains to be investigated.

Objectives: To profile acute gut microbial community alterations in response to PD DAT initiation.

Methods: Clinical data and stool samples were collected from 21 PD patients initiating either deep brain stimulation (DBS) or levodopa–carbidopa intestinal gel (LCIG) and ten spousal healthy control (HC) subjects. 16S amplicon sequencing of stool DNA enabled comparison of …


Breast Density Notification: A Systematic Review Of The Impact On Primary Care Practitioners, Brooke Nickel, Tessa Copp, Meagan Brennan, Rachel Farber, Kirsten Mccaffery, Nehmat Houssami Jan 2021

Breast Density Notification: A Systematic Review Of The Impact On Primary Care Practitioners, Brooke Nickel, Tessa Copp, Meagan Brennan, Rachel Farber, Kirsten Mccaffery, Nehmat Houssami

Medical Papers and Journal Articles

Background: In the last decade, there has been an unprecedented amount of advocacy and attention surrounding the issue of breast density (BD) in relation to mammography screening. It is largely unknown what impact notifying women of their BD has had on clinical practice for PCPs. This systematic review aimed to synthesize evidence from existing studies to understand the impact of BD notification on primary care practitioners' (PCPs) knowledge, attitudes, and practice implications.

Methods: Empirical studies were identified through relevant database searches (database inception to May 2020). Two authors evaluated the eligibility of studies, extracted and crosschecked data, and assessed the …


Mental State Of Demoralisation Across Diverse Clinical Settings: A Systematic Review, Meta-Analysis And Proposal For Its Use As A ‘Specifier’ In Mental Illness, Lucy L. Gan, Susanna Gong, David W. Kissane Jan 2021

Mental State Of Demoralisation Across Diverse Clinical Settings: A Systematic Review, Meta-Analysis And Proposal For Its Use As A ‘Specifier’ In Mental Illness, Lucy L. Gan, Susanna Gong, David W. Kissane

Medical Papers and Journal Articles

Objective: Demoralisation is a state of poor coping characterised by low morale, hopelessness, subjective incompetence, and loss of meaning and purpose in life. While studied extensively in oncology and palliative care, there has been recent exploration in broader medical and mental health settings. The aim was to investigate the prevalence of demoralisation and associated sociodemographic and psychological factors across these clinical settings.

Method: Six electronic databases were used to locate articles from January 2014 to March 2020. A pre-publication update of non-oncology populations was completed in September 2021. The review has been reported following Preferred Reporting Items for Systematic Reviews …


Summit Avenue Studios: A Creative Hub In Scott's Addition, Elizabeth Berry Jan 2021

Summit Avenue Studios: A Creative Hub In Scott's Addition, Elizabeth Berry

Theses and Dissertations

In this fast-paced life that seems to be moving at an even more rapid speed, we rely upon online retailers and the ability to purchase anything we need with a few taps on the phone or clicks on the computer. It can be wonderful to have this kind of exposure, but it comes at a price. We are trading convenience for craft, and risk overlooking talent in our own community. Most of these purchases are made from big box stores and online retailers selling cheap, international goods. We continue to lose the connection to our neighbors and communities, and local …


Shape Shifting: Bodies, Sound, And Queerness, Cordylia B. Vann Jan 2021

Shape Shifting: Bodies, Sound, And Queerness, Cordylia B. Vann

Theses and Dissertations

Writings in support of my visual and sonic thesis, Performing Ourselves. The paper examines the relationship between the labor of creating a queer body in how it moves and feels to the creation of choreography, sound, and graphic scores


Using Deep Learning-Based Framework For Child Speech Emotion Recognition, Gerald N. Onwujekwe Jan 2021

Using Deep Learning-Based Framework For Child Speech Emotion Recognition, Gerald N. Onwujekwe

Theses and Dissertations

Biological languages of the body through which human emotion can be detected abound including heart rate, facial expressions, movement of the eyelids and dilation of the eyes, body postures, skin conductance, and even the speech we make. Speech emotion recognition research started some three decades ago, and the popular Interspeech Emotion Challenge has helped to propagate this research area. However, most speech recognition research is focused on adults and there is very little research on child speech. This dissertation is a description of the development and evaluation of a child speech emotion recognition framework. The higher-level components of the framework …


E-Cigarette Use And Perceptions Among Adolescents With Attention-Deficit/Hyperactivity Disorder: The Role Of Parental Messages About Tobacco, Mayra S. Ramos Jan 2021

E-Cigarette Use And Perceptions Among Adolescents With Attention-Deficit/Hyperactivity Disorder: The Role Of Parental Messages About Tobacco, Mayra S. Ramos

Theses and Dissertations

Adolescents with attention-deficit/hyperactivity disorder (ADHD) are at increased risk of using e-cigarettes compared to their neurotypical peers. Parent-adolescent communication about tobacco use and number of ADHD symptoms can influence adolescents’ perceptions of e-cigarettes and their e-cigarette use. Adolescents with ADHD (n = 80) completed questionnaires assessing parental messages about tobacco use; e-cigarette harm perceptions; susceptibility to use e-cigarettes; and e-cigarette use. Parents reported on messages about tobacco use, adolescent’s ADHD symptomatology, and completed demographic questionnaires. Twenty-percent of adolescents reported e-cigarette ever use. Adolescent girls were significantly more likely to report higher e-cigarette harm perceptions than boys. Parents reported providing messages …


Rheological Analysis Of The Mechanical Properties Of Murine Lungs Over The Lifespan, Olajumoke Olufunke Harrison Jan 2021

Rheological Analysis Of The Mechanical Properties Of Murine Lungs Over The Lifespan, Olajumoke Olufunke Harrison

Theses and Dissertations

To study the effects of aging in murine lungs, we characterized C57Bl6j mice from neonatal to 24-month-old mice. Samples were divided into two groups: Young Mice (YM) and Middle Age/Old Age Mice (MOM). The YM group included the neonatal and 6-10week. The MOM group included 7- and 22–24-month-old mice. Rheological testing was performed using a TA Instruments DHR-2 Rheometer to collect the mechanics of each mice sample. Utilizing a 20-mm parallel plate fixture, a gap of 0.8-1.0-mm, and a temperature setting of 25C, we conducted a frequency sweep. Samples were the decellularized over a four-day process then lyophilized for mass …


Impact Of Physical Activity And Cardiorespiratory Fitness On Vascular Homeostasis In Premenopausal Women Consuming A Westernized High-Fat Meal, Lauren N. Pedersen Jan 2021

Impact Of Physical Activity And Cardiorespiratory Fitness On Vascular Homeostasis In Premenopausal Women Consuming A Westernized High-Fat Meal, Lauren N. Pedersen

Theses and Dissertations

A large percentage of adults in industrialized nations consume a Westernized dietary pattern, which contributes to fasting dyslipidemia and increased risk for atherosclerotic cardiovascular disease. Evidence suggests that a single Westernized meal containing high saturated fat may induce alterations in blood lipids as well as disturb multiple factors regulating peripheral vascular homeostasis, including innate immune cell function, oxidative stress, and vascular function. Conversely, participation in acute and chronic exercise may beneficially impact an individual’s postprandial response. Therefore, this dissertation contains three manuscripts seeking to describe how acute exercise, cardiorespiratory fitness, and physical activity level impact the lipemic and vascular homeostatic …


Therapeutic Modalities For Preventing Osteoarthritis Following Trauma To The Knee, Kayla M. Scott Jan 2021

Therapeutic Modalities For Preventing Osteoarthritis Following Trauma To The Knee, Kayla M. Scott

Theses and Dissertations

Over 32.5 million adults in the United States and 300 million worldwide have osteoarthritis (OA). To date, there are no disease-modifying therapeutics, only strategies to slow OA progression through pain management, regenerative medicine approaches, and ultimately joint replacement.

On a microscale, a phenotypic shift of the normally quiescent articular chondrocytes leads to aberrant expression of pro-inflammatory and catabolic pathways, which are hypothesized to contribute to OA progression. Of note, interleukin-1β (IL-1β), tumor necrosis factor-α (TNF-α), and WNT/β-catenin signaling are key players disrupting cartilage homeostasis and driving inflammatory pathway activation. These pathways become dysregulated and form a positive feedback loop, increasing …


A Deep Learning U-Net For Detecting And Segmenting Liver Tumors, Vidhya Cardozo Jan 2021

A Deep Learning U-Net For Detecting And Segmenting Liver Tumors, Vidhya Cardozo

Theses and Dissertations

Visualization of liver tumors on simulation CT scans is challenging even with contrast-enhancement, due to the sensitivity of the contrast enhancement to the timing of the CT acquisition. Image registration to magnetic resonance imaging (MRI) can be helpful for delineation, but differences in patient position, liver shape and volume, and the lack of anatomical landmarks between the two image sets makes the task difficult. This study develops a U-Net based neural network for automated liver and tumor segmentation for purposes of radiotherapy treatment planning. Non-contrast simulation based abdominal CT axial scans of 52 patients with primary liver tumors were utilized. …


Development Of Unnatural Amino Acid Mutagenesis Technologies To Control Enzyme Activity And Synthesis Of Chemically Reactive Ubiquitin Probes, Jenny Cheung Jan 2021

Development Of Unnatural Amino Acid Mutagenesis Technologies To Control Enzyme Activity And Synthesis Of Chemically Reactive Ubiquitin Probes, Jenny Cheung

Theses and Dissertations

Most of the work vital for the survival of the cell are performed by proteins. The primary sequence of proteins is composed of 20 canonical amino acids. However, these 20 amino acids do not offer the full range of functionalities needed for proteins to do their job. Often times, post-translational modifications (PTM’s) occur to add the required functional group. This interaction between all the different proteins in the proteome in addition to PTM’s create a complex system that scientists are still trying to unravel to this day. Many different tools had been developed for this purpose, and one such tool …


Examining The Impact Of Entrepreneurship Training On Entrepreneurial Mindset And Economic Well-Being, Sombo Muzata Jan 2021

Examining The Impact Of Entrepreneurship Training On Entrepreneurial Mindset And Economic Well-Being, Sombo Muzata

Theses and Dissertations

This study used a mixed methods research design to examine the impact of entrepreneurship training on entrepreneurial mindset and economic well-being using the RVA Works Entrepreneurship Training Program as a case study. With human capital theory as a theoretical framework, a combination of 55 interviews and 36 surveys were used to answer the research questions. The study found that entrepreneurship training positively impacts an entrepreneurial mindset. The impact of the training on entrepreneurial mindset differed by participants age and educational level. Study participants applied their entrepreneurial mindset to their businesses, jobs, and other aspects of life. Participation in the program’s …


A General Framework For Characterizing And Evaluating Attacker Models For Cps Security Assessment, Christopher S. Deloglos, Christopher Deloglos Jan 2021

A General Framework For Characterizing And Evaluating Attacker Models For Cps Security Assessment, Christopher S. Deloglos, Christopher Deloglos

Theses and Dissertations

Characterizing the attacker’s perspective is essential to assessing the security posture and resilience of cyber-physical systems. The attacker’s perspective is most often achieved by cyber-security experts (e.g., red teams) who critically challenge and analyze the system from an adversarial stance. Unfortunately, the knowledge and experience of cyber-security experts can be inconsistent leading to situations where there are gaps in the security assessment of a given system. Structured security review processes (such as TAM, Mission Aware, STPA-SEC, and STPA-SafeSec) attempt to standardize the review processes to impart consistency across an organization or application domain. However, with most security review processes, the …


Inquiries In Intelligent Information Systems: New Trajectories And Paradigms, Samaa Elnagar Jan 2021

Inquiries In Intelligent Information Systems: New Trajectories And Paradigms, Samaa Elnagar

Theses and Dissertations

Rapid Digital transformation drives organizations to continually revitalize their business models so organizations can excel in such aggressive global competition. Intelligent Information Systems (IIS) have enabled organizations to achieve many strategic and market leverages. Despite the increasing intelligence competencies offered by IIS, they are still limited in many cognitive functions. Elevating the cognitive competencies offered by IIS would impact the organizational strategic positions.

With the advent of Deep Learning (DL), IoT, and Edge Computing, IISs has witnessed a leap in their intelligence competencies. DL has been applied to many business areas and many industries such as real estate and manufacturing. …


Behavioral And Quantitative Electroencephalogram Alterations During The Whisker Nuisance Task Following Mild Traumatic Brain Injury In Mice, David Wildman Jan 2021

Behavioral And Quantitative Electroencephalogram Alterations During The Whisker Nuisance Task Following Mild Traumatic Brain Injury In Mice, David Wildman

Theses and Dissertations

Mild traumatic brain injury (mild TBI) has been shown to cause an array of symptoms in individuals lasting up to several years. Several publications have lead researchers to believe that parvalbumin axotomy and its associated changes with gamma oscillations may be the driving force for these symptoms. Several publications have demonstrated alterations in both resting gamma and evoked gamma by way of parvalbumin dysfunction. Our research analyzed resting and evoked gamma obtained by electroencephalograms (EEG) in nine mild TBI mice and six SHAM mice by utilizing a behavioral test known as the Whisker Nuisance Task (WNT). The central fluid percussion …