Digital Commons Network^™

Flesh And Circuit: Rethinking Performance And Technology, Conor Mcgarrigle, E L. Putnam

Articles

The live, embodied, material, and interactive qualities of performance have made it a notable means of exploring the creative potential of technological engagement, acting as a critical vector for revealing and resisting the technological colonisation of everyday life. The innovative collaborations of Experiments in Art and Technology (EAT) during the 1960’s with artists such as Yvonne Rainer and Robert Rauschenberg, Stelarc’s extreme body modifications, Dumb Type’s intermedia performance, and Guillermo Gomez-Pena and La Pocha Nostra’s poetic and speculative imaginings, have mapped the advances in technology and opened new creative fields to explore embodiment. However, there are still some significant oversights …

Environment Protection And Public Policies: The Case Of The Brazilian System Of Protected Areas (Snuc), Wainesten Da Silva

International Programs

This poster aims to present the Brazilian System of Protected Areas (SNUC), which is the result of the enforcement of the Brazilian society in promoting public policies to reduce the impact of human activity in nature. It has presented the concept of a public policy, a short history of public policies regarding the environment in Brazil, the main points of the Brazilian System of Protected Areas (SNUC), and a map exposing the protected areas in Brazil. The main finding is that the SNUC is a strong instrument to promote public policies to protect the environment, not only excluding the use …

An Analysis Of Commercial Guitar Styles Through The Study Of Notable Los Angeles Session Musicians, Edward Mitchell

Recital Papers

An Analysis of Commercial Guitar Styles Through the Study of Notable Los Angeles Session Musicians

Glis1 Regulates Trabecular Meshwork Function And Intraocular Pressure And Is Associated With Glaucoma In Humans., K Saidas Nair, Chitrangda Srivastava, Robert V Brown, Swanand Koli, Hélène Choquet, Hong Soon Kang, Yien-Ming Kuo, Sara A Grimm, Caleb Sutherland, Alexandra Badea, G Allan Johnson, Yin Zhao, Jie Yin, Kyoko Okamoto, Graham Clark, Terete Borrás, Gulab Zode, Krishnakumar Kizhatil, Subhabrata Chakrabarti, Simon W M John, Eric Jorgenson, Anton M Jetten

Faculty Research 2021

Chronically elevated intraocular pressure (IOP) is the major risk factor of primary open-angle glaucoma, a leading cause of blindness. Dysfunction of the trabecular meshwork (TM), which controls the outflow of aqueous humor (AqH) from the anterior chamber, is the major cause of elevated IOP. Here, we demonstrate that mice deficient in the Krüppel-like zinc finger transcriptional factor GLI-similar-1 (GLIS1) develop chronically elevated IOP. Magnetic resonance imaging and histopathological analysis reveal that deficiency in GLIS1 expression induces progressive degeneration of the TM, leading to inefficient AqH drainage from the anterior chamber and elevated IOP. Transcriptome and cistrome analyses identified several glaucoma- …

From Mathematics To Medicine: A Practical Primer On Topological Data Analysis (Tda) And The Development Of Related Analytic Tools For The Functional Discovery Of Latent Structure In Fmri Data, Andrew Salch, Adam Regalski, Hassan Abdallah, Raviteja Suryadevara, Michael J. Catanzaro, Vaibhav A. Diwadkar

Mathematics Faculty Research Publications

fMRI is the preeminent method for collecting signals from the human brain in vivo, for using these signals in the service of functional discovery, and relating these discoveries to anatomical structure. Numerous computational and mathematical techniques have been deployed to extract information from the fMRI signal. Yet, the application of Topological Data Analyses (TDA) remain limited to certain sub-areas such as connectomics (that is, with summarized versions of fMRI data). While connectomics is a natural and important area of application of TDA, applications of TDA in the service of extracting structure from the (non-summarized) fMRI data itself are heretofore nonexistent. …

Developing Methods To Detect And Diagnose Chronic Traumatic Encephalopathy During Life: Rationale, Design, And Methodology For The Diagnose Cte Research Project, Michael L Alosco, Daniel S Marcus, Et Al.

2020-Current year OA Pubs

BACKGROUND: Chronic traumatic encephalopathy (CTE) is a neurodegenerative disease that has been neuropathologically diagnosed in brain donors exposed to repetitive head impacts, including boxers and American football, soccer, ice hockey, and rugby players. CTE cannot yet be diagnosed during life. In December 2015, the National Institute of Neurological Disorders and Stroke awarded a seven-year grant (U01NS093334) to fund the "Diagnostics, Imaging, and Genetics Network for the Objective Study and Evaluation of Chronic Traumatic Encephalopathy (DIAGNOSE CTE) Research Project." The objectives of this multicenter project are to: develop in vivo fluid and neuroimaging biomarkers for CTE; characterize its clinical presentation; refine …

Time To Re-Evaluate Taniguchi Jiro's Pace In Manga, Natsume Fusanosuke, Jon Holt, Teppei Fukuda

World Languages and Literatures Faculty Publications and Presentations

Natsume Fusanosuke is Emeritus Professor of the Graduate Program of Cultural Studies in Corporeal and Visual Representation, Gakushūin University. Despite his recent retirement from Gakushūin in March, he is still very active in manga criticism and scholarship. Originally a manga artist himself in the 1980s, by the 1990s he began doing more writing about manga, although he often still employs his cartooning skills to assist in his analysis and explanation of his subjects, much like his American contemporary Scott McCloud. It is not a stretch to compare the latter’s Understanding Comics to Natsume's work in the classic How to Read …

Behavioral And Productive Parameters Of Lactating Dairy Cows As Indicators Of The Early Detection Of Metabolic And Digestive Diseases, Juan Manuel Vergara

International Programs

No abstract provided.

The Age And Growth Of The Yellow Stingray (Urobatis Jamaicensis) In Southeast Florida, Jessica Schieber

All HCAS Student Capstones, Theses, and Dissertations

The yellow stingray, Urobatis jamaicensis (Cuvier 1816), is a coastal species that has limited known life-history information, especially regarding their age and growth patterns. Age estimates were assigned by counting band-pairs deposited on the vertebral centrum of stingrays caught between 2003 and 2019 (n = 195). Marginal increment analysis of different size classes was used to validate age estimates, with the largest class having verified annual band deposition (ANOVA, F(9,7), P = 0.029). Age estimates ranged between females, and rates, but females attained larger sizes with the largest observed DW being 241-mm and 216-mm for females and males, respectively. …

Playing Through The Motions: A Stylistic Analysis Of Brand Identity On Tiktok, Anthony Laboriel

All HCAS Student Capstones, Theses, and Dissertations

The short-form video-sharing application TikTok has blossomed from a standard piece of social media into the multi-use platform known in households around the world. A consideration of how brand identities are created in online spaces has much to offer scholars in communication studies and rhet/comp. This project examines how brand identity and audiences are formed through analyzing successful brands and the content they post. My research applies a stylistic analysis, drawing from theories proposed by Ethan Bresnick, Donald Murray, and Carolyn Mae Kim, to observe five well known pages on TikTok: Chipotle, the National Basketball Association (NBA), Netflix, The Washington …

1:38, Yuhao Sheng

Theses

This thesis support paper demonstrated the entire process of creating this thesis film "1:38," describing how this film completed from a simple inspiration to a finished film project. Besides, this paper also describes how the author's ideas formed from the beginning and his inner struggle during the quarantine period, which inspired the author to create this film. Thirdly, this paper clarifies how the whole film team worked and our considerations about different problems during the film shooting. I believe this paper would be a good reference for the students to shoot their films with a low budget.

Family & Friends, Volume 2, Number 7

Family & Friends, 1998-2006

Anita C. Moyt, Managing Editor. Contributors: J. Shane Wilson, Dana Ferguson, Steven Bradford, Melinda McSparrin, Laine McNeil, Rex Wockner

Special thanks to Rhodes College and the Paul Barret Jr. Library for providing initial scanning of this collection.

Family & Friends, Volume 3, Number 2

Family & Friends, 1998-2006

Anita C. Moyt, Managing Editor. Contributors: J. Shane Wilson, Dana Ferguson, Steven Bradford, Melinda McSparrin, Laine McNeil, Rex Wockner, Gip Plaster, John Anderson, Hal Harmon.

Special thanks to Rhodes College and the Paul Barret Jr. Library for providing initial scanning of this collection.

Family & Friends, Volume 3, Number 1

Family & Friends, 1998-2006

Anita C. Moyt, Managing Editor. Contributors: J. Shane Wilson, Dana Ferguson, Steven Bradford, Melinda McSparrin, Laine McNeil, Rex Wockner, Gip Plaster, John Anderson, Hal Harmon.

Special thanks to Rhodes College and the Paul Barret Jr. Library for providing initial scanning of this collection.

Phosphatidylethanolamine N-Methyltransferase (Pemt) Knockout Mice Exhibit Worse Alcohol-Induced Liver Injury Than Wildtype Mice, Ireland M. Murphy, Matthew C. Paal, Srinivas Chava, Madan Kumar Arumugam, Kusum K. Kharbanda

Posters: 2021 Summer Undergraduate Research Program

Phosphatidylethanolamine N-methyltransferase (PEMT) is an enzyme that catalyzes the successive transfer of 3 methyl groups from S-adenosylmethionine (SAM) to phosphatidylethanolamine (PE) to generate phosphatidylcholine (PC). PC is vital for exporting fat out of the liver, ultimately preventing hepatic steatosis. Alcohol also induces steatosis partly through damaging this pathway, so the purpose of this study was to investigate the relationship between alcohol and PEMT in the liver. PEMT -/- (KO) and wild-type (WT) mice were subjected to a chronic + binge alcohol treatment, and both serum and liver samples were analyzed. Triglyceride quantification, SAM and S-adenosylhomocysteine (SAH) levels, and histological analyses …

Cell Death Mechanism In An Isolated Wood Smoke Inhalation Induced-Ards Large Animal Model, Panashe T. Muendesi, Hannah R. Weber Mfs, Premila D. Leiphrakpam Phd, Keely L. Buesing Md

Posters: 2021 Summer Undergraduate Research Program

Acute respiratory distress syndrome (ARDS) is a lethal disease condition in critically ill patients with a reported mortality rate reaching 45%. The current treatment modalities available for severe ARDS are invasive and carry significant risk for patients. Most published studies involving smoke inhalation utilize another simultaneous injury (such as cutaneous burn) to increase pathology burden of their animal models. This introduces confounding variables to investigations which aim to concentrate on inhalation injury. In this study, we evaluated the potential molecular targets associated with isolated smoke inhalation-induced ARDS.

We observed an increase in lung injury score and wet/dry ratio 48h post …

Systematic Review Of Preclinical Surgical Meshes For Hernia Repair, Andrew Hedstrom, Nathan Bills, Cynthia M. Schmidt, Mark A. Carlson

Posters: 2021 Summer Undergraduate Research Program

Hernia repair is one of the most common procedures performed around the world. Surgical mesh materials are used to reinforce hernia repairs and improve surgical outcomes. However, current commercial mesh materials produce problems such as infection, rejection, shrinkage, adhesion, and mechanical failure. These problems contribute to a high rate of hernia recurrence and mesh removal. With the number of hernias expected to rise in the future due to increases in obesity and diabetes, the need for more effective mesh materials is critical. This review aims to identify, evaluate, and summarize experimental surgical mesh materials used in the preclinical stages of …

Productivity Trends And Pattern Of Scientific Collaboration Of Bibliometric Research: An Exploratory Analysis, Sk Sofik, Ziaur Rahman Dr, Sabahat Nausheen Dr

Library Philosophy and Practice (e-journal)

Bibliometrics is an emerging thrust area of research and has become a standard tool of science policy and research management in the last decades and attracted much attention because of the substantial expansion of literature. This study aims to systematically review the worldwide productivity trends, the pattern of scientific collaboration, and research outputs of Bibliometrics research from Web of Science (WoS) web database, Science Citation Index Expanded (SCI-E). A bibliographic database of scientific papers published by authors affiliated worldwide, and containing the keywords “Bibliometric(s)” or “Scientometric(s)” or “Informetric(s)” or “Altmetric(s)” was built. A corpus of 9,630 publications was obtained and …

Developing Methods To Detect And Diagnose Chronic Traumatic Encephalopathy During Life: Rationale, Design, And Methodology For The Diagnose Cte Research Project, Jeffrey Cummings, Numerous Authors, See Full List Below

School of Medicine Faculty Research

Background: Chronic traumatic encephalopathy (CTE) is a neurodegenerative disease that has been neuropathologically diagnosed in brain donors exposed to repetitive head impacts, including boxers and American football, soccer, ice hockey, and rugby players. CTE cannot yet be diagnosed during life. In December 2015, the National Institute of Neurological Disorders and Stroke awarded a seven-year grant (U01NS093334) to fund the “Diagnostics, Imaging, and Genetics Network for the Objective Study and Evaluation of Chronic Traumatic Encephalopathy (DIAGNOSE CTE) Research Project.” The objectives of this multicenter project are to: develop in vivo fluid and neuroimaging biomarkers for CTE; characterize its clinical presentation; refine …

Beyond Disenchantment: Toward A Sociology Of Wonder, Steve Derné, Nicole Safford, Meagan Odette, Ruben Mercado, Sarah Wright, Nicholas Garmendiz, Lesly Ann Ureña Reyes, Christine Price, Julia Kinel, Amanda Vick, Dana Basile, Samantha Dorn, Chloe Wnuk, Robert Mcfarlane, Brooke Reich, Maelee Sanford

Sociology

Focusing on disenchantment, sociology undertheorizes wonder. Our analysis of 30 interviews is the first sociological study of Americans’ wonder experiences. Contrary to Weber’s theorization of disenchantment, this study shows people experience wonder that is transformative and try to cultivate states of mind open to wonder experiences. Our study shows wonder follows from particularity, difference, and encounters with the mysterious; wonder connects people to expansive concerns; people experience acute self-awareness during wonder encounters; and people seek wonder experiences. Wonder communities influence wonder experiences, but stages of wonder experiences are similar outside communities.

Heterotrophic Dinoflagellate Growth And Grazing Rates Reduced By Microplastic Ingestion, Victoria M. Fulfer, Susanne Menden-Deuer

Graduate School of Oceanography Faculty Publications

Microplastics are ubiquitous contaminants in marine ecosystems worldwide, threatening fisheries production, food safety, and human health. Ingestion of microplastics by fish and large zooplankton has been documented, but there are few studies focusing on single-celled marine predators, including heterotrophic dinoflagellates. In laboratory experiments, the heterotrophic dinoflagellate species Oxyrrhis marina and Gyrodinium sp. readily ingested both algal prey and polystyrene microplastic spheres (2.5–4.5 μm), while Protoperidinium sp. did not ingest microplastics. Compared to algae-only fed dinoflagellates, those that ingested microplastics had growth rates reduced by 25–35% over the course of 5 days. Reduced growth resulted in a 30–50% reduction of secondary …

Macrocyclic Immunoproteasome Inhibitors As A Potential Therapy For Alzheimer's Disease, Ahreum Baek, In Jun Yeo, Seongsoo Lee, Zachary Miller, Sukyeong Lee, Jin Tae Hong, Dong-Eun Kim, Wooin Lee, Kyung Bo Kim

Faculty, Staff and Students Publications

Previously, we reported that immunoproteasome (iP)-targeting linear peptide epoxyketones improve cognitive function in mouse models of Alzheimer's disease (AD) in a manner independent of amyloid β. However, these compounds' clinical prospect for AD is limited due to potential issues, such as poor brain penetration and metabolic instability. Here, we report the development of iP-selective macrocyclic peptide epoxyketones prepared by a ring-closing metathesis reaction between two terminal alkenes attached at the P2 and P3/P4 positions of linear counterparts. We show that a lead macrocyclic compound DB-60 (

Racial/Ethnic Disparities In Alzheimer’S Disease Risk: Role Of Exposure To Ambient Fine Particles, Diane Younan, Xinhui Wang, Tara Gruenewald, Margaret Gatz, Marc L. Serre, William Vizuete, Meredith N. Braskie, Nancy F. Woods, Ka Kahe, Lorena Garcia, Fred Lurmann, Joann E. Manson, Helena C. Chui, Robert B. Wallace, Mark A. Espeland, Jiu-Chiuan Chen

Psychology Faculty Articles and Research

Background

Whether racial/ethnic disparities in Alzheimer’s disease (AD) risk may be explained by ambient fine particles (PM_2.5) has not been studied.

Methods

We conducted a prospective, population-based study on a cohort of Black (n=481) and White (n=6004) older women (aged 65-79) without dementia at enrollment (1995-98). Cox models accounting for competing risk were used to estimate the hazard ratio (HR) for racial/ethnic disparities in AD (1996-2010) defined by DSM-IV and the association with time-varying annual average PM_2.5 (1999-2010) estimated by spatiotemporal model.

Results

Over an average follow-up of 8.3 (±3.5) years with 158 incident cases (21 in …

Inflammation And Altered Signaling In Obstetric Pathologies, Ya-Fang Tsai

Theses and Dissertations

The purpose of this research project was to elucidate the molecular interactions and detail the signaling pathways in obstetric pathologies. This work first seeks to understand inflammation related complications relevant to obstetrics. Prior research in our lab identified the implications of the receptor of advanced glycation end products (RAGE) during inflammatory response in the placenta. Current work identified the presence of DNA double-strand breaks (DNA-DSBs) in inflammation associated pregnancy complications of preeclampsia (PE) and preterm labor (PTL) and demonstrated the positive role of RAGE in repairing the damage. The confluent relevance of disrupted mitochondrial function and inflammation has been recognized …

Longitudinal Assessment Of Cytokine Expression And Plasminogen Activation In Hantavirus Cardiopulmonary Syndrome Reveals Immune Regulatory Dysfunction In End-Stage Disease, Peter Simons, Yan Guo, Virginie Bondu, Susan L. Tigert, Michelle Harkins, Samuel Goodfellow, Cana Tompkins, Devon Chabot-Richards, Xuexian O. Yang, Laura Gonzalez Bosc, Steven Bradfute, Daniel A. Lawrence, Tione Buranda

Pathology Research and Scholarship

Pathogenic New World orthohantaviruses cause hantavirus cardiopulmonary syndrome (HCPS), a severe immunopathogenic disease in humans manifested by pulmonary edema and respiratory distress, with case fatality rates approaching 40%. High levels of inflammatory mediators are present in the lungs and systemic circulation of HCPS patients. Previous studies have provided insights into the pathophysiology of HCPS. However, the longitudinal correlations of innate and adaptive immune responses and disease outcomes remain unresolved. This study analyzed serial immune responses in 13 HCPS cases due to Sin Nombre orthohantavirus (SNV), with 11 severe cases requiring extracorporeal membrane oxygenation (ECMO) treatment and two mild cases. We …

Mss0240. Smith-Buckingham Papers Finding Aid

Special Collections Finding Aids

The collection contains original and transcribed letters and fragments, essays, reminiscences, and other documents dating from the early 1800s to the 1970s. The nineteenth century items are predominately from the Neely and Pitser Miller families of Bolivar and Memphis, as well as the Jacob Smiths of Maine, Minnesota, and Tennessee. Twentieth century materials include an account by Hugh Evelyn Buckingham of his experiences as an artillery officer in France in 1918, and a few letters from Nash Buckingham, the well-known outdoorsman and writer.

View the collection

Toward A Cohesive Management Of Earth’S Orbital Environment: Applying Policy And Collaboration To A Design For The Present And Future, Charles Lee Mudd Jr.

Small Satellite Conference

The response to Starlink solar reflectivity by some industry leaders, scientists, and other interested actors demonstrates the ability for diverse space actors to collaborate through dialogue and innovation to solve nuanced technological problems. These efforts should be encouraged and modeled to implement a response to and prevention of future dynamics that affect Earth’s orbital environment. In a separate but related context, the Federal Communications Commission (“FCC”) proposed and implemented new regulations regarding orbital debris. In 2021, the final regulations on orbital debris mitigation should be adopted, published, and implemented. This context suggests that the policy climate within the FCC should …

Empirical Fitting Of Periodically Repeating Environmental Data, Pavel Bělík, Andrew Hotchkiss, Brandon Perez, John Zobitz

Spora: A Journal of Biomathematics

We extend and generalize an approach to conduct fitting models of periodically repeating data. Our method first detrends the data from a baseline function and then fits the data to a periodic (trigonometric, polynomial, or piecewise linear) function. The polynomial and piecewise linear functions are developed from assumptions of continuity and differentiability across each time period. We apply this approach to different datasets in the environmental sciences in addition to a synthetic dataset. Overall the polynomial and piecewise linear approaches developed here performed as good (or better) compared to the trigonometric approach when evaluated using statistical measures (R^{2 …}

Understanding The Metabolic Regulation Of Trained Immunity By Palmitic Acid, Khaleda Aqaei, Brooke A. Napier

McNair Symposium

Sepsis is an inflammatory disease that occurs when the body’s response to an infection becomes dysregulated, and infection-fighting processes of the body damage tissues via inflammation, resulting in organ failure and death. Currently, the role for diet in regulating sepsis susceptibility and severity is not fully understood. The Western Diet (WD), the most prevalent diet worldwide, is high in saturated fatty acids (SFAs) and sucrose, and low in fiber. Previously, we have used a lipopolysaccharide (LPS)-induced sepsis mouse model to show that mice fed a Western Diet (WD) or a diet enriched only in SFAs (Ketogenic Diet; KD), experience increased …

A Novel Approach To An Autonomous And Dynamic Satellite Control System Using On-Orbit Machine Learning, Maximum Wilder-Smith, Michael Pham, Matteo Gironda, Kevin Kwik, Michael Gee, Ryan Toomer, Samuel Bennett, Nicholas Shewchuk, Ashley Mcbean, Tarek Elsharhawy

Small Satellite Conference

Classical control methods require deep analytical understanding of the system to be successfully controlled. This can be particularly difficult to accomplish in space systems where it is difficult, if not impossible, to truly replicate the operational environment in a laboratory. As a result, many missions, especially in the CubeSat form factor, fly with control systems that regularly fail to meet their operational requirements. Failure of a control system might result in diminished science collection or even a total loss of mission in severe circumstances. Additionally, future SmallSat use cases (such as for orbital debris collection, repair missions, or deep space …