Digital Commons Network^™

Cfd Analysis Of Subcutaneous Deposition And Dispersion Of Insulin In Adipose Tissue, Ryan C. Lubbers

Masters Theses

Drug delivery is the most important factor of many therapies, but a lack of technology and research have led to a very generalized understanding of drug kinetics. Insulin pump therapy for the treatment of Type 1 Diabetes depends on precise delivery of the hormone into the adipose region between the dermis and underlying muscle. The kinetics of insulin within the adipose tissue environment is not well understood and varies greatly case to case. The use of computation fluid dynamics (CFD) models to study insulin kinetics in relation to influential factors will lead to a better understanding of the characteristics of …

Mosquito Distribution And West Nile Virus Surveillance Results On The Nevada National Security Site In South-Central Nevada, Derek B. Hall, Vivek Raman

Western North American Naturalist

A 10-year study (2004–2013) was conducted to determine mosquito distribution and the prevalence of West Nile virus (WNV) on the Nevada National Security Site (NNSS) in south-central Nevada. Mosquito traps baited with dry ice were set overnight at sites where standing water provided potential breeding sites for mosquitoes. Captured mosquitoes were identified to species and tested for WNV. A total of 556 mosquitoes representing 6 species were captured and identified at 20 sites around the NNSS during 124 surveys. A vast majority (89%) of mosquitoes were Culex tarsalis. Two samples, both Culiseta inornata, tested positive for WNV in …

Triangle Journal News, Volume 11, Number 12

Triangle Journal News, 1990-2006

Editors: Allen Cook, John Stilwell, Angela Lamb. Columnists/Contributors: Paula Martinac, Butch Valentine, Romeo San Vicente, Lorri L. Jean, Shannon Yarbrough, Rawley Grau, Jim Maynard, Angela Lamb. Production: Allen Cook, Bob Dumais, John Stilwell. Advertising: Bob Dumais, Allen Cook. National Advertising: Rivendell Marketing Company.

Special thanks to Rhodes College and the Paul Barret Jr. Library for providing initial scanning of this collection.

Triangle Journal News, Volume 9, Number 8

Triangle Journal News, 1990-2006

Co-Editors: Allen Cook, John Stilwell. Staff Writers: Vincent Astor, Ira L. King. Contributors: David Bianco, Paula Martinac, Chuck Saylor, Romeo St. Vicente, Jim Maynarrd, Butch Valentine, Simon LeVay, Ph.D. Production: Vincent Astor, Allen Cook, Bob Dumais, John Stilwell. Advertising: Vincent Astor, Bob Dumais, Ed Bridges.

Special thanks to Rhodes College and the Paul Barret Jr. Library for providing initial scanning of this collection.

Sunday Times-Figaro, Memphis, 25:15, 1896

Sunday Times-Figaro

Vol. 25, No. 15 of "The Sunday Times-Figaro", a weekly magazine published in Memphis, Tennessee, on March 15, 1896. Pages 1-2 are missing. "The Sunday Times" contained short stories, local news, theatrical news and cartoons.

Triangle Journal News, Volume 12, Number 1

Triangle Journal News, 1990-2006

Editors: Allen Cook, John Stilwell, Angela Lamb. Columnists/Contributors: Paula Martinac, Butch Valentine, Romeo San Vicente, Lorri L. Jean, Shannon Yarbrough, Rawley Grau, Jim Maynard, Angela Lamb. Production: Allen Cook, Bob Dumais, John Stilwell. Advertising: Bob Dumais, Allen Cook. National Advertising: Rivendell Marketing Company.

Special thanks to Rhodes College and the Paul Barret Jr. Library for providing initial scanning of this collection.

Triangle Journal News, Volume 10, Number 10

Triangle Journal News, 1990-2006

Editors: Allen Cook, John Stilwell, Angela Lamb. Columnists: Paula Martinac, Butch Valentine, Romeo San Vicente. Contributors: Chuck Saylor, Hal Harmon, Vincent Astor. Production: Allen Cook, Bob Dumais, John Stilwell. Advertising: Bob Dumais, Allen Cook.

Special thanks to Rhodes College and the Paul Barret Jr. Library for providing initial scanning of this collection.

Canonical Nf-Κb Promotes Lung Epithelial Cell Tumour Growth By Downregulating The Metastasis Suppressor Cd82 And Enhancing Epithelial-To-Mesenchymal Cell Transition, Eugenia Roupakia, Evangelia Chavdoula, Georgia Karpathiou, Giannis Vatsellas, Dimitrios Chatzopoulos, Angeliki Mela, Jennifer M. Gillette, Katharina Kriegsmann, Mark Kriegsmann, Anna Batistatou, Anna Goussia, Kenneth B. Marcu, Emmanouil Karteris, Apostolos Klinakis, Evangelos Kolettas

Pathology Research and Scholarship

BACKGROUND: The development of non-small cell lung cancer (NSCLC) involves the progressive accumulation of genetic and epigenetic changes. These include somatic oncogenic

METHODS: Human NSCLC cells were used to knock-down RelA/p65 (RelA/p65

RESULTS: RelA/p65

CONCLUSIONS: Canonical NF-κB signalling promotes NSCLC, in part, by downregulating the metastasis suppressor CD82/KAI1 which inhibits cell migration, EMT and tumour growth.

The Third Generation Of Pan-Canadian Wetland Map At 10 M Resolution Using Multisource Earth Observation Data On Cloud Computing Platform, Masoud Mahdianpari, Brian Brisco, Jean Granger, Fariba Mohammadimanesh, Bahram Salehi, Saeid Homayouni, Laura Bourgeau-Chavez

Michigan Tech Publications, Part 1

Development of the Canadian Wetland Inventory Map (CWIM) has thus far proceeded over two generations, reporting the extent and location of bog, fen, swamp, marsh, and water wetlands across the country with increasing accuracy. Each generation of this training inventory has improved the previous results by including additional reference wetland data and focusing on processing at the scale of ecozone, which represent ecologically distinct regions of Canada. The first and second generations attained relatively highly accurate results with an average approaching 86% though some overestimated wetland extents, particularly of the swamp class. The current research represents a third refinement of …

Dormant Bud Development In Phalaris Aquatica L., Brendan R. Cullen, P. E. Quigley, D. F. Chapman

IGC Proceedings (1977-2023)

The formation of dormant buds is critical to the summer survival of phalaris (Phalaris aquatica L.) in pastures. Dormant buds are formed on the base of reproductive tillers as they develop in spring. This project aimed to determine the seasonal pattern of dormant bud development and the influence of grazing management on bud dynamics. Approximately three buds per reproductive tiller were formed in the spring and early summer period. These buds responded to summer rainfall, with one third of buds becoming active following a 15-mm rainfall event in mid summer. In the following growing season, on average, 1.5 buds …

Tillering Dynamics Of Panicum Maximum Jacq. Cv. Tanzania-1 After Grazing, Rodrigo A. Barbosa, Domicio Nascimento Jr., Valéria P. B. Euclides, A. J. Regazzi, D. M. Fonseca

IGC Proceedings (1977-2023)

Tillering dynamics and tiller dry matter weight from Tanzania grass (Panicum maximum cv. Tanzania-1) were evaluated in two post-grazing stubbles (High Post-grazing Stubble – HPS-3.6 t of DM/ha and Low Post-grazing Stubble – LPS-2.3 t of DM/ha). There was no difference between post-grazing stubbles for decapitated axillary and basal remainder and new axillary tillers. The LPS presented greater number of new basal tillers. The rate of appearance of new basal and axillary tillers decreased with time after grazing. There were differences between the treatments on tiller dry matter weight, and greater values were found in the high post-graze stubble.

The Influence Of Tas2r38 Bitter Taste Gene Polymorphisms On Obesity Risk In Three Racially Diverse Groups, Chaowanee Chupeerach, Pradtana Tapanee, Nattira On-Nom, Piya Temviriyanukul, Boonrat Chantong, Nicole Reeder, Grace A. Adegoye, Terezie Tolar-Peterson

BioMedicine

Objectives: Bitter taste perception affects food preference, eating behavior, and nutrient intake. The purpose of this study was to investigate the contribution of bitter taste gene polymorphisms to body fatness as measured by percentage of body fat.

Method: Three common single nucleotide polymorphisms (SNPs) of the TAS2R38 gene which result in amino acid changes in the protein (A49P, V262A, and I296V), were studied in three racially diverse groups: European Americans n=313, African Americans n=109, and Asians n=234.

Results: The allele frequencies of the three SNPs were similar to previous studies. The rare haplotypes, AAI and AAV, were found in high …

Konjac Glucomannan Polysaccharide And Inulin Oligosaccharide Ameliorate Dextran Sodium Sulfate-Induced Colitis And Alterations In Fecal Microbiota And Short-Chain Fatty Acids In C57bl/6j Mice, Chih-Hsuan Changchien, Cheng-Hsin Wang, Hsiao-Ling Chen

BioMedicine

Background: Konjac glucomannan polysaccharide (KGM), inulin oligosaccharide (inulin) and their mixture has been shown to modulate the gut-associated lymphoid tissue immunity.

Aims: The present study was mainly to determine effects of a low-level (2% w/w) KGM and inulin and their combination on dextran sodium sulfate (DSS)-induced colitis. We also determine the potential mechanisms mediating these effects of dietary fibers.

Methods: C57BL/6J mice (6 weeks of age, eight per group) were randomly assigned to consume one of the following diets: control (DSS group) or control diet supplemented with 2% (w/w) of KGM (KGM group), 2% (w/w) of inulin oligosaccharide (degree of …

The Panathenaic Festival, Alison Hughes

Ephemeris

No abstract provided.

Hannibal's Importance In The Second Punic War, Steve Nery

Ephemeris

No abstract provided.

Senior Research Abstract: Pigs In Antiquity, Christopher Bungard

Ephemeris

No abstract provided.

Suitable Seed Harvesting Time For Six Grass Species, Hossein Arzani, A. Fakhireh

IGC Proceedings (1977-2023)

Determination of the best period of seed harvesting was considered. Six grass species were selected. The research was conducted in three stations of Alborz, Sirachal and Homand Absard. According to maturing stages, seed collection for measuring seed water content (moisture content), weight of 1000 seeds and germination percentage has been done. The result showed that there were significant differences between harvesting time on seed germination for all species in all regions. Moisture content, germination rate, weight of 1000 seeds and seed shedding were important characteristics for determination of suitable seed harvesting time.

Effect Of Nitrogen Fertilizer On Reproductive Tiller Development In Perennial Ryegrass, I. Bahmani, E. R. Thom, C. Matthew, G. Lemaire

IGC Proceedings (1977-2023)

The objective of this study was to compare reproductive tiller development in two ryegrass (Lolium perenne L.) cultivars, when fertilized with nitrogen. Plots of the cultivars ‘Grasslands Ruanui’ and ‘Ellett’ ryegrass were sown in April 1996. Half of each plot received nitrogen fertilizer (30 kg N/ha) after each grazing by dairy cows from September 1996 to May 1997 and from October 1997 to April 1998. Ryegrass tiller dynamics was monitored from September 1996 to March 1998. The proportion of reproductive tillers in the total tiller population was higher, on average, over the first flowering period (October 1996 to January …

Daedalus And Icarus: An Exerpt From A Journey Delayed, A Modern Retelling Of Ovid's Metamorphoses, Melanie Vanderkolk

Ephemeris

No abstract provided.

Photo Montage, Karen Sikloski

Ephemeris

No abstract provided.

Victory As Self-Representation, Allison Cartmell

Ephemeris

No abstract provided.

Recipe Of Success, Meridith Sulser

Ephemeris

No abstract provided.

The Contemporary Tax Journal Volume 10, No. 2 – Summer 2021

The Contemporary Tax Journal

No abstract provided.

Use Of Intravitreal Methotrexate Infusion In Complicated Retinal Detachment For Prevention Of Proliferative Vitreoretinopathy In A Pilot Study, Sana Jahangir, Tehmina Jahangir, Muhammad H. Ali, Qasim Lateef, Uzma Hamza, Haroon Tayyab

Section of Ophthalmology

Objective: The objective of this pilot study was to evaluate the efficacy and safety of per-operative intravitreal methotrexate (MTX) infusion during vitrectomy in patients of retinal detachment (RD) with advanced grade proliferative vitreoretinopathy (PVR).
Methods: In this prospective interventional case series, we included patients with Grade C PVR, recurrent RD, and open globe trauma. All patients underwent standard single surgeon operated 23-gauge pars plana vitrectomy (PPV) with 80mg of MTX in 1000mL of irrigation fluid. All patients were followed up after four months to assess the final status of retinal attachment and visual acuity. Ethical review board permission was sought …

Down The Iron Path: Mitochondrial Iron Homeostasis And Beyond, Jonathan Dietz, Jennifer L. Fox, Oleh Khalimonchuk

Department of Biochemistry: Faculty Publications

Cellular iron homeostasis and mitochondrial iron homeostasis are interdependent. Mitochondria must import iron to form iron–sulfur clusters and heme, and to incorporate these cofactors along with iron ions into mitochondrial proteins that support essential functions, including cellular respiration. In turn, mitochondria supply the cell with heme and enable the biogenesis of cytosolic and nuclear proteins containing iron–sulfur clusters. Impairment in cellular or mitochondrial iron homeostasis is deleterious and can result in numerous human diseases. Due to its reactivity, iron is stored and trafficked through the body, intracellularly, and within mitochondria via carefully orchestrated processes. Here, we focus on describing the …

Exploration Of Gratitude In Cardiovascular Health: Mediators, Medication Adherence And Psychometrics, Lakeshia A. Cousin

Dissertations

The purpose of this dissertation was to explore the effect of gratitude on cardiovascular health outcomes using mediators, medication adherence, and psychometrics. The specific aims were to (1) establish the state of the science for gratitude and cardiovascular health outcomes via a state-of-the-science literature review, (2) explore mediators affecting gratitude and medication adherence using a structural equation model in patients with cardiovascular disease, and (3) analyze the psychometric properties of the Gratitude Questionnaire-6, a self-report questionnaire designed to assess individual differences to express dispositional gratitude, to provide evidence for the validity and reliability of the instrument in African Americans at …

Elephant Seal Muscle Cells Adapt To Sustained Glucocorticoid Exposure By Shifting Their Metabolic Phenotype, Julia María Torres-Velarde, Sree Rohit Raj Kolora, Jane I. Khudyakov, Daniel E. Crocker, Peter H. Sudmant, José Pablo Vázquez-Medina

Pacific Faculty Work

Elephant seals experience natural periods of prolonged food deprivation while breeding, molting, and undergoing postnatal development. Prolonged food deprivation in elephant seals increases circulating glucocorticoids without inducing muscle atrophy, but the cellular mechanisms that allow elephant seals to cope with such conditions remain elusive. We generated a cellular model and conducted transcriptomic, metabolic, and morphological analyses to study how seal cells adapt to sustained glucocorticoid exposure. Seal muscle progenitor cells differentiate into contractile myotubes with a distinctive morphology, gene expression profile, and metabolic phenotype. Exposure to dexamethasone at three ascending concentrations for 48 h modulated the expression of six clusters …

A Cancer Ubiquitome Landscape Identifies Metabolic Reprogramming As Target Of Parkin Tumor Suppression, Ekta Agarwal, Aaron R Goldman, Hsin-Yao Tang, Andrew V Kossenkov, Jagadish C Ghosh, Lucia Languino, Valentina Vaira, David W Speicher, Dario C Altieri

Department of Cancer Biology Faculty Papers

Changes in metabolism that affect mitochondrial and glycolytic networks are hallmarks of cancer, but their impact in disease is still elusive. Using global proteomics and ubiquitome screens, we now show that Parkin, an E3 ubiquitin ligase and key effector of mitophagy altered in Parkinson's disease, shuts off mitochondrial dynamics and inhibits the non-oxidative phase of the pentose phosphate pathway. This blocks tumor cell movements, creates metabolic and oxidative stress, and inhibits primary and metastatic tumor growth. Uniformly down-regulated in cancer patients, Parkin tumor suppression requires its E3 ligase function, is reversed by antioxidants, and is independent of mitophagy. These data …

Asking A Chatbot For Covid-19 Food And Nutrition, Fahmi Fahmi, Yusrandi Yusrandi, Aji Prasetya Wibawa, Ming Foey Teng, Purnawansyah Purnawansyah

Bulletin of Culinary Art and Hospitality

Coronavirus 19 (COVID-19) is a disease caused by a new coronavirus called severe acute respiratory syndrome Coronavirus 2 (SARS-CoV-2; previously known as 2019-nCoV). On March 11, 2020, WHO declared COVID-19 a global pandemic, the first pandemic since H1N1 influenza was declared a pandemic in 2009. The disease has hit almost every country in the world and so far, no medicine nor antiviral was found. In some countries where the death rate is high, the number of patients continues to increase. On May 20, 2020, the number of patients exceeded 4.8 million and the toll is 318,000 (6.6 percent). Although the …

Why Should People Use Face Masks In The Time Of Covid? The Jri Position, Jose Bordon, Alex Glynn, Forest W. Arnold

The University of Louisville Journal of Respiratory Infections

No abstract provided.