Digital Commons Network^™

Jane Austen’S Lady Susan As A Possible Source Of Inspiration Behind C.S. Lewis’S The Screwtape Letters, Song Cho

Mythlore: A Journal of J.R.R. Tolkien, C.S. Lewis, Charles Williams, and Mythopoeic Literature

No abstract provided.

Nsaids Naproxen, Ibuprofen, Salicylate, And Aspirin Inhibit Trpm7 Channels By Cytosolic Acidification, Rikki Chokshi, Orville Bennett, Tetyana Zhelay, J. Ashot Kozak

Neuroscience, Cell Biology & Physiology Faculty Publications

Non-steroidal anti-inflammatory drugs (NSAIDs) are used for relieving pain and inflammation accompanying numerous disease states. The primary therapeutic mechanism of these widely used drugs is the inhibition of cyclooxygenase 1 and 2 (COX1, 2) enzymes that catalyze the conversion of arachidonic acid into prostaglandins. At higher doses, NSAIDs are used for prevention of certain types of cancer and as experimental treatments for Alzheimer’s disease. In the immune system, various NSAIDs have been reported to influence neutrophil function and lymphocyte proliferation, and affect ion channels and cellular calcium homeostasis. Transient receptor potential melastatin 7 (TRPM7) cation channels are highly expressed in …

Vol. 61, No. 08 (October 18, 2021)

Indiana Law Annotated

No abstract provided.

Constructing Frameworks For Task-Optimized Visualizations, Ghulam Jilani Abdul Rahim Quadri

USF Tampa Graduate Theses and Dissertations

Visualization is crucial in today’s data-driven world to augment and enhance human understanding and decision-making. Effective visualizations must support accuracy in visual task performance and expressive data communication. Effective visualization design depends on the visual channels used, chart types, or visual tasks. However, design choices and visual judgment are co-related, and effectiveness is not one-dimensional, leading to a significant need to understand the intersection of these factors to create optimized visualizations. Hence, constructing frameworks that consider both design decisions and the task being performed enables optimizing visualization design to maximize efficacy. This dissertation describes experiments, techniques, and user studies to …

The Shape Of Water In J.R.R. Tolkien’S The Lord Of The Rings, Norbert Schürer

Mythlore: A Journal of J.R.R. Tolkien, C.S. Lewis, Charles Williams, and Mythopoeic Literature

Water is omnipresent in many shapes and forms in J.R.R. Tolkien’s The Lord of the Rings. To most critics, this water symbolizes melancholy, hope, and salvation—but then these scholars treat all water as if it were the same. In contrast, I demonstrate that there are six always intertwined and overlapping aspects or facets of representations of water: instrumental (to move the plot forward), geographical (to set up distinctions and boundaries), figurative (images of water employed in rhetorical devices), mystical (magical incarnations of water), pathetic (mirroring the emotions of characters), and intentional (creating meaning by prefiguring and intensifying character’s ideas and …

Paro As A Biofeedback Medical Device For Mental Health In The Covid-19 Era, Takanori Shibata, Lillian Hung, Sandra Petersen, Kate Darling, Kaoru Inoue, Katharine Martyn, Yoko Hori, Geoffrey Lane, Davis Park, Ruth Mizoguchi, Chihiro Takano, Sarah Harper, George W. Leeson, Joseph F. Coughlin

Nursing Faculty Publications and Presentations

The COVID-19 pandemic is spreading across the globe, and it could take years for society to fully recover. Personal protective equipment (PPE), various hygiene measures, and social distancing have been implemented to reduce "human to human" contact, which is an essential part of outbreak prevention. The pressure of the pandemic combined with decreased communication and social contact have taken a toll on the mental health of many individuals, especially with respect to anxiety and depression. Effective use of robots and technology as a substitute for--or in coordination with--traditional medicine could play a valuable role in reducing psychological distress now more …

Literate Activity Research And Narrative Analysis As Frameworks For Educational Change: An Examination Of Writing Instruction In Two Alternative Education Programs, Leslie Rae Hancock

Theses and Dissertations

How are narratives, as mediating cultural tools within activity systems, influencing or shaping the ways in which alternative high school teachers are designing, developing, and implementing their writing instruction? This thesis seeks to answer this guiding research question by investigating the writing pedagogies and praxis of two Illinois alternative school teachers. Using literate activity research and narrative analysis as guiding frameworks for the research, a qualitative study was conducted to examine participants’ activity systems and their uptake of two broader cultural narratives: the “at-risk student” and “general writing skills instruction” narratives. Data was collected over the course of the study …

The Regulation Of Plant Vegetative Phase Transition And Rejuvenation: Mirnas, A Key Regulator, Tajbir Raihan, Robert L. Geneve, Sharyn E. Perry, Carlos M. Rodriguez Lopez

Horticulture Faculty Publications

In contrast to animals, adult organs in plants are not formed during embryogenesis but generated from meristematic cells as plants advance through development. Plant development involves a succession of different phenotypic stages and the transition between these stages is termed phase transition. Phase transitions need to be tightly regulated and coordinated to ensure they occur under optimal seasonal, environmental conditions. Polycarpic perennials transition through vegetative stages and the mature, reproductive stage many times during their lifecycles and, in both perennial and annual species, environmental factors and culturing methods can reverse the otherwise unidirectional vector of plant development. Epigenetic factors regulating …

Performance Study Of Spot Cooling Of Tractor Cabinet., A. Kabeel, Gamal Sultan, Z. Zyada, M. El-Hadary

Mansoura Engineering Journal

The target of this research is to study theoretically and experimentally the performance of spot cooling of a tractor cabinet including a single internal heat source (tested body) by using vortex tube. In the theoretical study, the cabinet is cooled from the roof by one port and constant wall temperature for lower and side walls. The effect of inlet and outlet air ports position in the cabinet is considered. Moreover, the influence of varing the inlet cold air velocity to cabinet from 2.7o 12.5 m/s inlet cold air temperature to cabinet (rom 282.1 to 29’7.3 K, inlet air pressure to …

Fusion Versus Fixation In Complex Comminuted C3-Type Tibial Pilon Fractures: A Systematic Review., Yash P Chaudhry, Efstratios Papadelis, Hunter Hayes, Philip F Stahel, Erik A Hasenboehler

Orthopedic Surgery Resident Research

BACKGROUND: Comminuted intra-articular tibial pilon fractures can be challenging to manage, with high revision rates and poor functional outcomes. This study reviewed [1] treatment, complications, and clinical outcomes in studies of complex comminuted tibial pilon fractures (type AO43-C3); and [2] primary ankle arthrodesis as a management option for these types of complex injuries.

METHODS: A systematic literature search was performed on PubMed from 1990 to 2020 to determine complications and outcomes after staged fracture fixation and primary ankle joint arthrodesis for comminuted C3-type tibial pilon fractures. The search was conducted in compliance with the PRISMA guidelines, using the following MeSH …

In Pursuit: A Mother’S Account Of Her Son’S Rare Disease Diagnosis Journey, Anne M. Jones

Journal of Patient-Centered Research and Reviews

A personal account from a mother’s perspective on her undiagnosed son’s medical journey over almost 6 years toward a diagnosis of a rare genetic variant in mitogen-activated protein kinase 8 interacting protein 3 (MAPK8IP3) resulting in neurodevelopment disorder.

Conference Proceedings: Select Abstracts Presented At 2021 Advocate Aurora Health Scientific Day

Journal of Patient-Centered Research and Reviews

Abstracts published within this supplement were presented at the 47th annual Advocate Aurora Health Scientific Day, held virtually on May 26, 2021. This research symposium provides a forum for disseminating results from studies conducted by faculty, fellows, residents, and other allied health professionals associated with Midwest-based health system Advocate Aurora Health, which publishes the Journal of Patient-Centered Research and Reviews.

Case Reports On Disorders Of Sound Tolerance: Misophonia And Hyperacusis, Madison Mcconville, Antony Joseph

AuD Capstone Projects - Communication Sciences and Disorders

Introduction: Misophonia is a rare disorder affecting approximately one in 1,500 people, of which, a small percentage are pediatric patients. Misophonia is characterized by the dislike of an explicit sound in a specific context. Treatment for misophonia includes a four-step program that can be modified for pediatrics. Case Presentation: A young female presented to the clinic with a significant distressed reaction when in the presence of specific sounds that included chewing, clicking pens, and loud music bass tones. Discussion: Treatment of misophonia is comparable to a care-plan for both tinnitus and hyperacusis. For this case, a four-step approach was used …

Tbx15/Mir-152/Kif2c Pathway Regulates Breast Cancer Doxorubicin Resistance Via Promoting Pkm2 Ubiquitination, Cheng-Fei Jiang, Yun-Xia Xie, Ying-Chen Qian, Min Wang, Ling-Zhi Liu, Yong-Qian Shu, Xiao-Ming Bai, Bing-Hua Jiang

Department of Medical Oncology Faculty Papers

Background: Chemoresistance is a critical risk problem for breast cancer treatment. However, mechanisms by which chemoresistance arises remains to be elucidated. The expression of T-box transcription factor 15 (TBX-15) was found downregulated in some cancer tissues. However, role and mechanism of TBX15 in breast cancer chemoresistance is unknown. Here we aimed to identify the effects and mechanisms of TBX15 in doxorubicin resistance in breast cancer.

Methods: As measures of Drug sensitivity analysis, MTT and IC50 assays were used in DOX-resistant breast cancer cells. ECAR and OCR assays were used to analyze the glycolysis level, while Immunoblotting and Immunofluorescence assays were …

Teaching English Language Varieties: Promoting Linguistic And Educational Change Through A Critical Multicultural Pedagogical Approach In The “Introduction To Linguistics ” Course, Lyudmila N. Belomoina

Theses and Dissertations

This dissertation introduces and analyzes a critical multicultural pedagogical approach to the introductory linguistics course focused on the introduction to the main levels of analysis within linguistics (phonetics, phonology, syntax, semantics, and pragmatics) in the context of standardized English; a nonstandardized English language variety, African American English (AAE); and a World English, Indian English (IE). The approach, which is based on the tenets of critical pedagogy and multicultural education, is centered on language variation and intended for K-12 future language arts teachers (and writing instructors at the college level) with the goal to teach them how to develop linguistically informed …

Trem2 Modulates Differential Deposition Of Modified And Non-Modified Aβ Species In Extracellular Plaques And Intraneuronal Deposits, Pranav Joshi, Florian Riffel, Sathish Kumar, Nàdia Villacampa, Sandra Theil, Samira Parhizkar, Christian Haass, Marco Colonna, Michael T Heneka, Thomas Arzberger, Jochen Herms, Jochen Walter

2020-Current year OA Pubs

Progressive accumulation of Amyloid-β (Aβ) deposits in the brain is a characteristic neuropathological hallmark of Alzheimer's disease (AD). During disease progression, extracellular Aβ plaques undergo specific changes in their composition by the sequential deposition of different modified Aβ species. Microglia are implicated in the restriction of amyloid deposits and play a major role in internalization and degradation of Aβ. Recent studies showed that rare variants of the Triggering Receptor Expressed on Myeloid cells 2 (TREM2) are associated with an increased risk for AD. Post-translational modifications of Aβ could modulate the interaction with TREM2, and the uptake by microglia. Here, we …

Faculty Senate Executive Committee Minutes, October 18, 2021, Utah State University

Faculty Senate & Faculty Senate Executive Committee

• Approval of Minutes – September 20, 2021
• University Business
• Educational Policies Committee
• Athletic Council Annual Report
• Honors Program Annual Report
• PRPC Report
• What kind of format for Faculty Senate meetings (in-person/Zoom)
• Vote on 401 and 402 code updates

Multiple-Brain Systems Dynamically Interact During Tonic And Phasic States To Support Language Integrity In Temporal Lobe Epilepsy, Shilpi Modi, Xiaosong He, Kapil Chaudhary, Walter Hinds, Andrew Crow, Ashithkumar Beloor-Suresh, Michael R Sperling, Joseph I Tracy

Department of Neurology Faculty Papers

An epileptogenic focus in the dominant temporal lobe can result in the reorganization of language systems in order to compensate for compromised functions. We studied the compensatory reorganization of language in the setting of left temporal lobe epilepsy (TLE), taking into account the interaction of language (L) with key non-language (NL) networks such as dorsal attention (DAN), fronto-parietal (FPN) and cingulo-opercular (COpN), with these systems providing cognitive resources helpful for successful language performance. We applied tools from dynamic network neuroscience to functional MRI data collected from 23 TLE patients and 23 matched healthy controls during the resting state (RS) and …

Chimes: October 18, 2021, Calvin University

Chimes

To avoid cutting budgets, CIL won't charter more student orgs this year by Grace Toma

'Luminous' tells of Calvin astronomer's risky prediction by Ezra Craker

Visa delays kept 20+ students from campus this fall by Abigail Ham

CISD mobilizes to combat food insecurity by Jocelyn Nunez-Colon

Calvin Left tells Arkansas senator to hit the road by Jocelyn Nunez-Colon & Savannah Shustack

Seven students and countless cameras: Streaming Calvin sports by Jamison Van Andel

Homeowners want to install solar panels. Consumers Energy obstructs them. by Sarah Gibes

All Worthy Things: The Personhood Of Nature In J.R.R. Tolkien’S Legendarium, Sofia Parrila

Mythlore: A Journal of J.R.R. Tolkien, C.S. Lewis, Charles Williams, and Mythopoeic Literature

This paper argues that J. R. R. Tolkien’s portrayal of plants, animals, and geographical features as morally complex persons is central to the ecocentric model of environmental stewardship developed within Tolkien’s legendarium. Tolkien’s Middle-earth writings endow non-human beings such as animals, plants, and even rivers with personhood by emphasizing their individuality, their capacity for interpersonal relationships, and their agency to make moral choices. I build on work done by critics such as Matthew Dickerson, and Jonathan Evans (Ents, Elves, and Eriador) to find a practicable and inspirational environmental ethic in Tolkien’s The Lord of the Rings, The Silmarillion, and Unfinished …

Lewis And Clarke In The Caves: Art And Platonic Worlds In Piranesi, Julie M. Dugger

Mythlore: A Journal of J.R.R. Tolkien, C.S. Lewis, Charles Williams, and Mythopoeic Literature

Susanna Clarke’s 2020 novel Piranesi openly acknowledges its debt to C.S. Lewis’s Chronicles of Narnia. Piranesi’s imagined world, the House, is modeled after Charn from The Magician’s Nephew in the Chronicles: both feature uninhabited and apparently endless series of halls. Clarke’s world is not Lewis’s, however. As she puts it, “I always liked Charn better than Lewis liked Charn,” and the House in Piranesi is not a cold, dead shell, but the beloved home of the novel’s eponymous narrator. Piranesi’s handling of the relationship between models (like Charn) and their differing imitations (like Piranesi's House) is important because a theme …

Mirrors To The Underworld: Reflective Portals Between Life And Death In The Harry Potter Series, Thea Juneau

Mythlore: A Journal of J.R.R. Tolkien, C.S. Lewis, Charles Williams, and Mythopoeic Literature

This article argues that reflective surfaces throughout all seven Harry Potter novels symbolize thresholds between discrete worlds. By displaying Harry’s dead parents on ‘the other side’ of the Mirror of Erised, the text draws on the Myth of Narcissus and various other mythological death-mirrors to create the impression of an inverse afterlife realm where the dead live again, supporting the central themes of death and grief in the series. By drawing upon Lori M. Campbell’s theory of object ‘porters,’ the article shows how the gradual transformation of this framework through more abstract reflections (eyes, creatures, lakes) reveals a deep symbolic …

“Taliessin In The Rose-Garden”: A Symbolic Analysis, Joseph Thompson

Mythlore: A Journal of J.R.R. Tolkien, C.S. Lewis, Charles Williams, and Mythopoeic Literature

In this analysis of a poem from Charles Williams’s Taliessin cycle, Taliessin in the Rose-Garden, I sought to demonstrate that our reading of the poem could be helped with the use of certain traditional categories of symbolism. In particular I focussed on how Williams adapts the classical model of hylomorphism to offer his own take on the relationship between spirit and matter. That he was able to accomplish this through the medium of poetry is a considerable testament to his skill and the scope of his vision. I also tried to show where hermetic ideas encroach upon his Christian storytelling, …

Re-Orienting The Fairy Tale: Contemporary Adaptations Across Cultures, Edited By Mayako Murai And Luciana Cardi, Nada Kujundžić

Mythlore: A Journal of J.R.R. Tolkien, C.S. Lewis, Charles Williams, and Mythopoeic Literature

No abstract provided.

Forage Yield And Nutritive Quality Of Haulm From Dual-Purpose Cowpea (Vigna Unguiculata L Walp) Cultivars For Dry Season Feeding In Nigeria, N. J. Anyanwu, Olufemi S. Onifade, Jimoh A. Olanite, V. I. O. Olowe, B. O. Boukar, I. I. Ekpe

IGC Proceedings (1977-2023)

The availability of high quality forage especially during the dry season remains a major challenge to ruminant livestock production in Nigeria and many parts of West Africa. Due to the prevailing mismatch between livestock population and supply of feed resources in the arid and semi arid Nigeria, the humid forest zone represents a potential source for crop residues, especially during the dry season due to longer rainfall duration and suitable climate. This study was conducted to evaluate forage yield and nutritive quality of haulm from selected dual purpose cowpea (Vigna unguiculata L. Walp.) cultivars in the humid rain forest …

Influence Of Seeding Rate On Growth Performance And Yield Of Early Maturing Sorghum, Ismail S. Selemani, O. B. Ngonyani

IGC Proceedings (1977-2023)

Heavy grazing pressure in Tanzanian semi-arid rangelands coupled with climate change and variability has resulted into severe decline in forage production and changes in vegetation composition. To increase forage biomass production in the face of climate change and variability, climate resilient fodder crops such as early maturing sorghum have been recommended in arid and semi-arid regions. However, paucity of information on the best agronomic practices especially the optimal seeding rate and row spacing fostered the need to carry out research on growth performance and yield of early maturing sorghum. The experiment was conducted at Magadu Dairy Farm to assess the …

Comparison Of Four Maize Cultivars (Zea Mays L.) As Winter Forage In Sudan, Rihab El Zubair

IGC Proceedings (1977-2023)

Winter forage availability in Sudan is constrained by lack of a suitable annual winter forage crop. The main forage crop grown is Abu70 (Sorghum bicolor) which is a summer crop that yields 7.6-8.4 t/ha in summer but much less in winter. There is, therefore, need for a winter high yielding forage crop that exceeds Abu70 in productivity and quality. This study was aimed to evaluate four forage maize cultivars as potential winter crops in central Sudan in terms of productivity and quality. An experiment was conducted using four maize forage cultivars. The experiment lasted for two consecutive seasons …

Title Evaluation Of Yields And Nutritive Composition Of Dual Purpose Sweet Potato Vine Cultivars For Forage Use, R. S. Kenana, A. I. Hoka, N. Ondabu, F. Ondabu, J. Mercy

IGC Proceedings (1977-2023)

The sweet potato vine (SPV) is a widely grown but underutilized feed resource for livestock. The vines have desirable characteristics suitable for fodder production due to high contents of protein and digestible energy. The objective of this study was to evaluate the yield and nutritive composition of five dual purpose cultivars based on vine production for forage use. The experimental design was arranged in randomized complete block design where six cultivars of sweet potato were established in plots of 2.5m x 2.5m in three replicates. The cultivars used were; Kenspot 1, 2, 3, 4, and 5. An improved forage type …

Diet Selection By Goats At Kalemando, North Darfur, Sudan, Abdelrahim I. H. Mansoor, Babo Fadlalla

IGC Proceedings (1977-2023)

Pressure on rangelands of Sudan has increased in the last few decades due to increase in human population and in animal numbers. The rangelands were also impacted by climate change, desertification, agricultural expansion, mining, and overgrazing. Decreased amounts of rainfall have impoverished the natural rangelands. Goats are capable of grazing on semi-desert regions characterized by low rainfall and scarce grazing plants. It is therefore necessary to know and enhance plant species preferred by goats to properly manage the rangelands. The present study was conducted at Kalemando, North Darfur State during the rainy season of year 2017 when most plants were …

Smallholder Farmer Seed Production Of Mulato Ii Hybrid Brachiaria In Thailand And Laos - Bringing Quality Forage Seeds Home To Africa, M. D. Hare

IGC Proceedings (1977-2023)

Seeds of Mulato II hybrid brachiaria [Urochloa ruziziensis (syn. Brachiaria ruziziensis) x U. brizantha (syn. B. brizantha) x U. decumbens (syn, B.decumbens)] produced by smallholder farmers in villages in northeast Thailand and northern Laos, under contract to Ubon Forage Seeds Co. Ltd, a tropical forage seed company in Thailand, have come home to Africa. Since 2012, over 20,000 kg of Mulato II seed have been exported from Thailand to Kenya. The seed is hand-harvested from seed-heads in Laos and by hand-sweeping the seed from the ground in Thailand. The farmers semi-clean the seed in the field …