Digital Commons Network^™

Hurricane Survivors' Attitudes Regarding The Therapeutic Benefits Of Animals, Tina Callwood

Walden Dissertations and Doctoral Studies

There is research on the benefits of animal-assisted interventions. However, no study was found on hurricane survivors' lived experience and their attitudes toward animals after a traumatic experience. The purpose of this hermeneutic phenomenological study was to explore the lived experience of hurricane survivors' attitudes toward their companion animals or other animals they interacted with after a natural disaster. The transactional theory of stress and coping was used to explain how participants appraised their stress and reduced it. Constructivism was used to uncover hurricane survivors' experiences and their attitudes toward animals after the disaster. The research question examined the lived …

Teacher And Parent Perception Of Cyberbullying In A Middle School Setting, Jacqueline Gallo

Walden Dissertations and Doctoral Studies

AbstractThe purpose of this mixed method study was to evaluate differences in cyberbullying perception and self-efficacy between teachers and parents. The study aimed to determine how teachers and parents reacted to cyberbullying. The importance of examining teacher and parent perception and self-efficacy in addressing cyberbullying determined the significance of intervention. The theoretical framework for the study was Bandura’s social learning theory. The purpose of this mixed method study was to examine the perceptions and self-efficacy of cyberbullying between teachers and parents as measured by the Peer Relations Assessment Questionnaire Revised and the Self-Efficacy Questionnaire. A sample that incorporated perception and …

Understanding Successful Strategies Human Service First-Level Managers Utilize When Addressing Workplace Incivility, Mary Elizabeth Barlow

Walden Dissertations and Doctoral Studies

The social problem of workplace incivility is a well-researched issue that impacts employees, work groups, and organizations across the nation. The purpose of this study was to understand how first-level human service managers describe employee turnover in relation to workplace incivility and what first-level human service managers view as successful strategies they have used to address workplace incivility. The theoretical framework utilized for this study was incivility spiral theory, as described by Andersson and Pearson. The purpose of this generic qualitative study was to gain an understanding of successful strategies that first-level human service managers utilize when addressing workplace incivility …

Haitian Informal Entrepreneurs' Ability And Motivation To Formalize Their Microbusinesses, Samanthessa Ramona Jacob

Walden Dissertations and Doctoral Studies

Microbusiness owners or informal entrepreneurs in developing countries make up 40 to 60% of the informal economy. With a steady increase in unemployment in rural areas of developing countries, individuals live under poverty levels and start microbusinesses as a mean to survive. The purpose of this qualitative study was to explore the factors that contribute to Haitian informal entrepreneurs' ability and motivation to transition into the formal sector. A narrative inquiry approach was used for this study to bring in-depth meaning to the experiences of informal entrepreneurs in Haiti. For this study, 18 individual interviews of Haitian or Haitian descendant …

Exploring The Private And Environmental Events Of Repeat Offenders Relative To Low Self-Control, Xavier Mims

Walden Dissertations and Doctoral Studies

The dissection of self-control theory itself has served as a supplemental platform for understanding how the lack of self-control can perpetuate criminal conduct. Previous research has indicated that employing self-control theory to predict criminal behavior has been widely supported by various forms of test samples, measurements, and methodologies. However, there remains a gap in the current literature regarding the internal-motivative factors between the relationship of the offender's criminal behaviors and self-control theory. Partial understanding of what the offender experiences constitutes a significant disparity between subjective concepts and actual accounts based on an offender's view on his personal life. Therefore, the …

Relating Overweight/Obesity And Psychosocial Outcomes Among Racial/Ethnic And Sexual Minority Adolescents, Cadene T. Douglas

Walden Dissertations and Doctoral Studies

Adolescents being overweight/obese is a public health crisis that threatens the health and welfare of adolescents going into adulthood and places a significant strain on society. It has been described as one of the most severe public health challenges of the 21st century by the World Health Organization. The pervasiveness of obesity in adolescents rose by 47.1% over the last three decades, and it disproportionally affects racial/ethnic minority lesbian, gay, and bisexual (LGB) persons. Guided by distal and proximal health behaviors, the minority stress model, and intersectionality, the purpose of this study was to examine whether being overweight or obese …

Territoriality As A Factor In Nursing Incivility, Carolyn Wright

Walden Dissertations and Doctoral Studies

AbstractIncivility and hazing in health care results in unsafe environments, not only for the nurse but also for the client, facility, and other health professionals. The project site, a privately owned medical clinic, has a high employee turnover rate with exit interviews indicating bullying and incivility from long-term nursing staff toward new employees as critical reasons for employee resignation. The literature offers minimal information regarding territoriality, a concept associated with aggressive (i.e., alpha) behaviors in animals and humans and incivility in nursing. The purpose of the project was to identify whether territoriality was a behavioral factor that may have contributed …

African Immigrants' U.S. Experience Of Mental Health, Mental Illness, And Help-Seeking, Bartholomew Edem-Enang

Walden Dissertations and Doctoral Studies

AbstractThe purpose of this study was to qualitatively examine and explore African immigrants’ U.S. experience of mental health, mental illness, and help-seeking. Mental health, mental illness, and help-seeking are misunderstood public health issues. Indigenous cultural stigma concerning mental illness and help-seeking and mistrust of Western medicine inhibit African immigrants from reporting mental illness and seeking treatment. The segmented assimilation theory (SAT) and cultural risk theory (CRT) and interpretive phenomenological analysis (IPA) were used to guide data collection and analysis. Data were collected from a sample of 9 African immigrants who migrated from countries within the Five Main Regions of Africa …

Alternative Treatment Method For Dementia In The Southwest Region Of Arizona, Angela May Lynch

Walden Dissertations and Doctoral Studies

The purpose of this qualitative professional administrative study was to explore anddevelop a new innovative method of treatment for dementia clients using reminiscence therapy (RT) in a proposed 24-hour care village in Tucson, Arizona. In this proposed 24- hour care village, patients would remain in an environment conducive to a safe and normal lifestyle. This administrative study is a qualitative study using grounded theory and sources of evidence included current research, personal interviews, and articles. Data were collected from interviews with 10 administrators of memory care facilities in Tucson, Arizona, to determine if existing administrative staff were aware of RT …

The Preparedness Of Suffolk County’S Emergency Managers For Drinking Water Disruptions, Richard Rotanz

Walden Dissertations and Doctoral Studies

AbstractFor many years, a chronic issue within Suffolk County, New York, one of the most populated counties in the country, is the deterioration of its drinking water along with its polluted beaches, lakes, and rivers, which are imperative for tourism and the fishing industry. However, little is known regarding the awareness of, and the preparedness towards, any disruptions of drinking water by the community of emergency managers. Narrowing this gap of knowledge was the purpose of this study. The research question examined the knowledge of, the attitudes, and the preparedness levels of the emergency management community of Suffolk County involving …

African American Male Ex-Felons' Perspectives Regarding Felon Disenfranchisement, Tymesha Alegra Whitehead

Walden Dissertations and Doctoral Studies

The tradition of disenfranchising those convicted in the United States of felony crimes has profound historical racial roots that have persisted for decades in the United States. The persistent practice of felon disenfranchisement in the 21st century challenges the essence of democracy, with over six million people disenfranchised. The need for major reform efforts to restore voting rights to ex-felons has been exposed due to this issue. The literature revealed no studies have been undertaken regarding this phenomenon in terms of those directly affected by it. Therefore, the purpose of this qualitative phenomenological study was to understand the effect of …

Cyberattacks Strategy For Nonprofit Organizations, Yawo Obimpe Kondo

Walden Dissertations and Doctoral Studies

Information system security managers (ISSM) in nonprofits face increased cyberattack cases because nonprofits often use basic technology to save on costs. Nonprofit owners and managers need solutions to secure their data from cyberattacks. Grounded in the general systems theory, the purpose of this qualitative multiple case study was to explore strategies ISSMs at nonprofit organizations employ to protect against cyberattacks. Participants included five IT managers and directors of information technology in charge of security management in nonprofit organizations in Maryland, the District of Columbia, and Virginia. Data was generated through interviews and reviews of archival documents. The data analysis technique …

Emotional Support Dogs’ Effects On Anxiety, Depression, And Somatization In Elementary Students, Truman Arthur James Spring

Walden Dissertations and Doctoral Studies

Within the last few decades, there has been an ever-increasing clinical role for trained emotional support dogs (ESD) and their trained therapists in hospitals, courtrooms, and schools. More recently, within the last 5 years, there has been a prevalent trend toward introducing ESDs into schools, which has created an ongoing controversy about the legitimacy of this practice due to the lack of objective data and research on the topic. In this study, archival data analysis was conducted using data from 68 students with elevated scores for anxiety, depression, or somatization, 34 of which were in the treatment group and the …

Managers’ Challenges Complying With Environmental Regulations In Ghana’S Mining Sector, Augustin Tandoh

Walden Dissertations and Doctoral Studies

Even though Ghana’s mining industry has been and continues to be of remarkable benefit to the national economy, environmental pollution continues to plague the industry. The purpose of the qualitative case study was to obtain the perceptions of 9 nongovernmental organization (NGO) stakeholders of the challenges faced by managers in the Ghanaian mining industry tasked with complying with Ghana Environmental Protection Agency (GEPA) regulations. Freeman’s stakeholder theory was the theoretical framework of the study. Data were collected from semistructured interviews with a purposive sample of Ghanaian and international NGO representatives who sought to work with, or even shame and pressure, …

A Study Of Public Awareness About The Threat Of Earthquakes, Mike Allen

Walden Dissertations and Doctoral Studies

Noticeably absent from the existing literature was a correlation study which would have gauged individual awareness for earthquakes. The literature search provided one quantifiable narrative that correlated college education with awareness about earthquakes; the study found that college graduates scored higher points on the awareness test for earthquakes than their counterparts who had no college education. The research question for this study examined the possible correlations between personal characteristics and awareness about earthquakes. A survey was developed and used to find hypothesized correlations between public awareness and a number of variables such as age, gender, education, income, and professional leadership. …

Molecular Responses To Catastrophic Molting In A Wild Marine Mammal, Anna Keith

University of the Pacific Theses and Dissertations

While most mammals shed their hair and skin either continuously or seasonally, northern elephant seals (Mirounga angustirostris) undergo an annual catastrophic molt, in which they shed their entire fur and underlying skin layer in the span of just three weeks. Due to the energetic and thermoregulatory constraints of molting and the large distances between their coastal rookeries and foraging grounds, elephant seals must remain on land and fast for the duration of their molt. Previous studies of molting northern elephant seals have examined endocrine and metabolic adjustments to fasting, but not the molecular processes underlying molting. We examined changes in …

Changes In The Vertical Stratification Of Neotropical Nymphalidae At Forest Edges In Relation To Light And Temperature Conditions, Brian Koji Oye

University of the Pacific Theses and Dissertations

The composition of neotropical fruit-feeding nymphalid butterflies assemblages often varies by location and stratum within a forest. Recent work has shown that vertical stratification in particular may serve as barrier to gene flow, indicating the potential role vertical stratification may play in evolution. At forest edges, the distinction between assemblages has been described to decrease, with species considered to be canopy specialists descending to the forest understory. The similarity in light conditions between the canopy and understory strata at edges or disturbed habitat is hypothesized to be responsible for this phenomenon. We conducted a study using standardized sampling to document …

The Effects Of Touchscreen Technology Usage On The Social Emotional Development Of Preschool-Aged Children, Amanda Marie Sharpe

University of the Pacific Theses and Dissertations

Technology plays an increasingly significant role in the lives of children and adults, and it is imperative to understand if and how it impacts the development of psychological processes and the subsequent behaviors of preschool-aged children so that we can better understand how to navigate guidelines for use and interventions for overuse. To better understand the relationship between screen time use and a child’s social emotional development, it is important to consider parent time on screens, child time on screens, and any effects an older sibling in the home or parental gender may have on their development. This study gathered …

Synthesis And Conformational Study Of Triazolylcyclohexanols And Trans-2-(Azaarylsulfanyl)-Cyclohexanols, Mulinde R. Ruyonga

University of the Pacific Theses and Dissertations

Amino-cyclohexanol derivatives have been successful models for pH-triggered conformational switches. By changing the groups on the amine nitrogen, these models provide a wide pH-range in which a switch can occur. The pH-induced switch of conformation can be monitored by 1H NMR.In this work, structurally similar trans-2-(azaarylsulfanyl)-cyclohexanol derivatives (Scheme 1) and trans-2-triazolylcyclohexanol derivatives (Scheme 2) have been explored for the first time as compounds with a potential for the analogous pH-induced conformational switch. The azaarylsulfanyl groups showed selective conformational flexibility while the triazolyl group showed a strong preference for the equatorial position. Further, conformational studies were done on a series of …

Bayesian-Derived Vancomycin Auc24h Threshold For Nephrotoxicity In Special Populations, Dan Ho

University of the Pacific Theses and Dissertations

A Bayesian-derived 24-hour area under the concentration-time curve over minimum inhibitory concentration from broth microdilution (AUC24h/MICBMD) ratio of 400 to 600 is recommended as the new monitoring parameter for vancomycin to optimize efficacy and minimize nephrotoxicity. The AUC24h threshold of 600 mg*h/L for nephrotoxicity was extrapolated from studies that assessed the general population. It is unclear if this upper threshold is consistent or varies when used in special populations such as critically ill patients, obese patients, patients with preexisting renal disease, and patients on concomitant nephrotoxins.The purpose of this study is to investigate the generalizability of the proposed vancomycin AUC24h …

Harnessing Transthyretin To Enhance The In Vivo Half-Life Of Human Interleukin-2 (Il-2), Fang Liu

University of the Pacific Theses and Dissertations

Protein therapeutics are available as cytokines, clotting factors, enzymes, hormones, growth factors, antibodies et al. They have been shown to be effective in treating a variety of important human diseases. Since human insulin was approved as the first recombinant protein therapeutic, this field has experienced rapid growth. One of the biggest challenges for protein therapeutics in clinical application is their short half-life. Except for monoclonal antibodies, which have serum half-life for weeks, most of the protein therapeutics have half-lives ranging from minutes to hours. Kidney filtration, proteasome degradation and liver metabolism are the main factors that attribute to their short …

Teaching Study Skills To College Students Using Checklist Training, Sarah T. Kong

University of the Pacific Theses and Dissertations

Deficits in the study skills of college students can lead to lower academic performance and disqualification. Although behavior analytic research has evaluated methods for teaching, structuring in-class notes, increasing attendance, and improving participation, no studies have evaluated methods for improving independent studying outside of the classroom using a single-case design. We evaluated the effects of a study skills training package using a multiple probe design across skills with college students. Sessions took place in a room arranged to emulate the typical study space found in a dorm or library. During sessions, participants were given a 3–6 page reading from a …

Development Of Miriplatin-Loaded Nanoparticles Against Non-Small Cell Lung Cancer, Zhongyue Yuan

University of the Pacific Theses and Dissertations

Lung cancer claims the highest mortality and the second-most estimated new cases among all oncological diseases [1]. Non-small cell lung cancer (NSCLC) accounts for approximately 85% of all newly diagnosed lung cancers [2]. Approximately 40% of newly diagnosed lung cancer patients are stage IV. For stage IIIB/IV NSCLC, cytotoxic combination chemotherapy is standard first-line chemotherapy. A regimen of platinum (cisplatin or carboplatin) plus paclitaxel, gemcitabine, docetaxel, vinorelbine, irinotecan, or pemetrexed is the recommended clinical treatment [3].

Cisplatin is the first-generation platinum-based anti-cancer drug. Although cisplatin is much more effective than other platinum drugs at the same dosage [4], accumulating reports …

Impact Of 17-Beta Estradiol And Moderate-Intensity Exercise On Mesenteric Arterial Function Of Uc Davis Type-2 Diabetes Mellitus Rats, Md Rahatullah Razan

University of the Pacific Theses and Dissertations

The studies in this dissertation were designed to investigate the impacts of estrogen (17-β estradiol/E2) and moderate-intensity exercise (MIE) on the mesenteric arterial (MA) function of the University of California Davis type-2 diabetes mellitus (UCD-T2DM) Rat model. Our recent report suggests that diabetes impairs MA vasorelaxation in both sexes of the UCD-T2DM model. Particularly, we reported that MA from prediabetic male rats showed a greater impairment compared to that in prediabetic females. However, when females become diabetic, they exhibit a greater vascular dysfunction than males. Therefore, the aim of the first study was to investigate whether female sex hormone, specifically …

Silver(I) And Copper(Ii) Complexes Of 1,10-Phenanthroline-5,6-Dione Against Phialophora Verrucosa: A Focus On The Interaction With Human Macrophages And Galleria Mellonella Larvae, Marcela Q. Granato, Thaís P. Mello Thaís P. Mello, Renata S Nascimento, Marcos D. Pereira, Thabatta L.S.A. Rosa, Maria C.V. Pessolani, Malachy Mccann Malachy Mccann, Michael Devereux, Marta H. Branquinha

Articles

Phialophora verrucosa is a dematiaceous fungus that causes mainly chromoblastomycosis, but also disseminated infections such as phaeohyphomycosis and mycetoma. These diseases are extremely hard to treat and often refractory to current antifungal therapies. In this work, we have evaluated the effect of 1,10-phenanthroline-5,6-dione (phendione) and its metal-based complexes, [Ag (phendione)2]ClO4 and [Cu(phendione)3](ClO4)2.4H2O, against P. verrucosa, focusing on (i) conidial viability when combined with amphotericin B (AmB); (ii) biofilm formation and disarticulation events; (iii) in vitro interaction with human macrophages; and (iv) in vivo infection of Galleria mellonella larvae. The combination of AmB with each of the test compounds promoted …

Advancing Our Understanding Of Corneal Herpes Simplex Virus-1 Immune Evasion Mechanisms And Future Therapeutics, Emily Greenam, Sophie Gallagher, Rana Khalil, Conor C. Murphy, Joan Ní Gabhann-Dromgoole

Articles

Herpes stromal keratitis (HSK) is a disease that commonly affects the cornea and external eye and is caused by Herpes Simplex Virus type 1 (HSV-1). This virus infects approximately 66% of people worldwide; however, only a small portion of these people will develop symptoms in their lifetime. There is no cure or vaccine available for HSV-1; however, there are treatments available that aim to control the inflammation caused by the virus and prevent its recurrence. While these treatments are beneficial to those suffering with HSK, there is a need for more effective treatments to minimise the need for topical steroids, …

Annual Report 2020-2021, Depaul University College Of Computing And Digital Media

CDM Annual Reports

LETTER FROM THE DEAN

As I write this letter during the beginning of the 2021–22 academic year, we have started to welcome the majority of our students to campus— many for the very first time, and some for the first time in a year and a half. It has been wonderful to be together, in-person, again. Four quarters of learning and working remotely was challenging, to be sure, but I have been consistently amazed by the resilience, innovation, and hard work of our students, faculty, and staff, even in the most difficult of circumstances. This annual report, covering the 2020–21 …

The Resilience Of Substantive Rights And The False Hope Of Procedural Rights: The Case Of The Second Amendment And The Seventh Amendment, Renée Lettow Lerner

GW Law Faculty Publications & Other Works

At first glance, there seem to be strong affinities between the Second Amendment and the Seventh Amendment. Both the right to keep and bear arms and the right to civil jury trial potentially empower ordinary citizens. Both could check elites.

But there are crucial differences between these rights. I focus on two of them here. The first is relatively straightforward; it concerns individual accountability—or the lack thereof—and the ability to understand responsibilities. Gun owners and users generally have individual responsibility for their actions, and the ability to understand their responsibilities. In contrast, by design civil jurors lack individual responsibility. And …

Eye Movement Desensitization And Reprocessing Therapy In Virtual Reality: Proof Of Concept, Kinslee Hammonds

Undergraduate Honors Theses

This research focuses on the integration of Eye Movement Desensitization and Reprocessing therapy (EMDR) and Virtual Reality (VR). EMDR is a therapeutic approach using bilateral stimulation to process distressing memories, emotions, and experiences. It is widely employed for conditions like PTSD, anxiety, and depression. The study involves the development of a proof-of-concept virtual reality tool tailored for EMDR therapy sessions. The tool comprises a bilaterally moving sphere within the user's VR environment, controllable by the therapist through a graphical interface on a computer. The therapist can dynamically adjust the sphere's color, speed, and sound to enhance the therapeutic process. The …

Vasopressin Regulates Daily Rhythms And Circadian Clock Circuits In A Manner Influenced By Sex, Kayla Rohr, Adam Telega, Alexandra Savaglio, Jennifer A. Evans

Biomedical Sciences Faculty Research and Publications

Arginine vasopressin (AVP) is a neurohormone that alters cellular physiology through both endocrine and synaptic signaling. Circadian rhythms in AVP release and other biological processes are driven by the suprachiasmatic nucleus (SCN) of the anterior hypothalamus. Loss of vasopressin signaling alters circadian behavior, but the basis of these effects remains unclear. Here we investigate the role of AVP signaling in circadian timekeeping by analyzing behavior and SCN function in a novel AVP-deficient mouse model. Consistent with previous work, loss of AVP signaling increases water consumption and accelerates recovery to simulated jetlag. We expand on these results to show that loss …