Digital Commons Network^™

Pleiotropic Anticoagulant Functions Of Protein S, Consequences For The Clinical Laboratory. Communication From The Ssc Of The Isth, Herm Jan M. Brinkman, Josefin Ahnström, Elisabetta Castoldi, Björn Dahlbäck, Richard A. Marlar

Pathology Research and Scholarship

Hereditary deficiencies of protein S (PS) increase the risk of thrombosis. However, assessing the plasma levels of PS is complicated by its manifold physiological interactions, while the large inter-individual variability makes it problematic to establish reliable cut-off values. PS has multiple physiological functions, with only two appearing to have significant anticoagulant properties: the activated protein C (APC) and tissue factor pathway inhibitor alpha (TFPIα) cofactor activities. Current clinical laboratory investigations for deficiency in PS function rely only on the APC-dependent activity. This communication presents an argument for reclassifying the qualitative PS deficiencies to differentiate the two major anticoagulant functions of …

Taxing Big Data: A Proposal To Benefit Society For The Use Of Private Information, Ziva Rubinstein

Fordham Intellectual Property, Media and Entertainment Law Journal

Artificial intelligence, the technology that is currently shaping our world, relies on the data that each individual supplies. In 2017, the Economist magazine asserted that “the world’s most valuable resource is no longer oil, but data.” This assertion is supported by the current data market, which became a hundred-billion-dollar industry in the data broker market alone. However, despite its immense value, individuals are not compensated when their data is collected, shared, or when that data is used to replace them in the job market. Further, companies are legally avoiding taxes on this resource, both during its collection and on the …

Cartouches, Catalogs, & Courtrooms: Using A Recent Legal Challenge In Egyptian Court To Examine Unanswered Questions In Cultural Heritage, Lawrence Keating

Fordham Intellectual Property, Media and Entertainment Law Journal

Ancient Egypt is known to the world for its rich culture steeped in arcane mysticism and for the dazzling treasures it left behind, which now populate the world’s most prominent cultural institutions. These and other cultural heritage objects, which capture and inspire masses as easily today as they did in their own time, are subject to growing controversy over their protection and utilization. As this debate moves from academic circles to the arena of public discourse, the need to revise legislation controlling cultural heritage objects is becoming increasingly clear. This Note uses a recent law- suit concerning an international exhibition …

Securities Regulation And Social Media, Seth C. Oranburg

Scholarly Articles

Federal securities regulation originally divided corporate finance into two neat categories, public and private. In 1933, private financing was limited to “sophisticated” investors but otherwise lightly regulated. Public financing became heavily regulated. In 1982, the SEC introduced Reg D, which introduced the concept of “general solicitation” to clarify the distinction between public and private offerings. Reg D is well understood to prohibit newspaper advertisements and permit direct solicitations to venture capital investors. This enabled great wealth consolidation in regions like Silicon Valley while effectively banning general solicitations in private offerings.

Now, social media communication challenges the definition of “general solicitation.” …

Backstories: The Kitchen Table Talk Cookbook, Cynthia Prescott, Maureen Sherrard Thompson

Digital Press Books

Sharing recipes is a form of intimate conversation that nourishes body and soul, family and community. Backstories: The Kitchen Table Talk Cookbook integrates formal scholarship with informal reflections, analyses of recipe books with heirloom recipes, and text with images to emphasize the ways that economics, politics, and personal meaning come together to shape our changing relationships with food. By embracing elements of history, rural studies, and women’s studies, this volume offers a unique perspective by relating food history with social dynamics. It is sure to inspire eclectic dining and conversations.

Cynthia C. Prescott is Professor of History at the University …

Introduction To Oceanography Syllabus And Reading List, Cornelia Winguth

Mavs Open Press Open Educational Resources - Archive

Professor Cornelia Winguth received a UTA CARES Adoption Stipend in 2020 to implement free educational resources in GEOL 1350 (Introduction to Oceanography). The syllabus with reading list is archived here.

West Chester University Zero Waste Atlas Campus Assessment 2021, Alex Freid, Grace Bowden, Andrew James

WCU Campus Sustainability Initiatives

In Spring 2021, West Chester University’s Office of Sustainability hired the Post- Landfill Action Network (PLAN) to support two Sustainability Peer Educators, Grace Bowden ‘21 and Andrew James ‘21, to conduct a holistic assessment of the University’s waste management system. WCU’s Climate Action Plan includes a goal of achieving zero waste (as defined by 90% diversion from landfills and incinerators), with no defined timeline for achievement. The plan also outlines a number of key next steps in working towards that goal, many of which have yet to be achieved as outlined in this report. WCU remains committed to reduce waste …

Actors And Law-Making In International Environmental Law, In Research Handbook On International Environmental Law (Malgosia Fitzmaurice Et Al. Eds, 2d Ed. 2021), Mark A. Drumbl, Kateřina Uhlířová

Books and Chapters

This chapter explores who makes international environmental law and which are the sources of international environmental law? Traditionally, the number of actors with international legal personality is limited. States were primary among this group, followed by international organizations. In recent years, however, considerable international environmental law effectively has been generated by non-governmental organizations, networked communities of experts, and administrative secretariats of treaty organizations. The expansion in the number of actors that, whether de jure or de facto, make international environmental law has diversified the sources of international environmental law. Sources of international law include treaties, custom, general principles of law, …

Structure Versus Agency Through A Materialist Lens, Alyssa Moreau

Spectrum

No abstract provided.

Svic Spotlight Film: Mask Up, Harm Down!, Zachary Loesch, Jodi Bezanson

Spectrum

No abstract provided.

Svic Spotlight Film: Plant Power At The University Of New Hampshire, Madeline Bronson, Michael Lindsey

Spectrum

No abstract provided.

2020 Foreign And International Legislative Review, Brittany Rowe

Animal Law Review

This Legislative Review highlights the animal law related legislative victories 2020 brought about on foreign and international fronts.

Using Augmented Reality As A Tool For Distance Learning Of Vsepr Theory, Isabelle Lopez

Scripps Senior Theses

Distance learning poses challenges in most academic settings, especially at the undergraduate laboratory level. Improving this mode of learning diminishes the impact of current events on young scientists’ development of foundational laboratory concepts. Our work explores the use of augmented reality (AR) in a laboratory setting. We developed a completely virtual valence shell electron pair repulsion (VSEPR) theory lab activity consistent with the goals of Keck Science Department’s Introduction to Chemistry course’s in-person VSEPR lab activity. We were able to maintain a hands-on learning experience for students while using a tool many students already own: an iPhone as an alternative …

The Intersection Between Black Hair And The Environment: Hair As A Site For Environmental Justice And Sustainability, Dafina Matiku

Scripps Senior Theses

Currently, we are facing several global crises that include but are not limited to climate change, food insecurity, pollution of the body and environment, as well as racial, gender, and class inequities. This thesis seeks to understand how the natural hair movement, which strives to omit toxic chemicals while embracing textured hair, can be a tool of reconnecting to nature. As humans we are intrinsically part of ecosystems and nature, we must find our niche in it instead of occupying and destroying our environment entirely. The methodology includes compiling a small array of experiences that show the nuance of hair …

Communion: Envisioning And Executing The Fourth National People Of Color Legal Scholarship Conference — The Largest Ever Gathering Of Minority Law Scholars, Anthony E. Varona

Articles

No abstract provided.

Tri-State Musical Journal, Memphis, 2:3, 1929

Documents

Copy of Vol. 2, No. 3 of "The Tri-State Musical Journal" published by Misha Feibish in Memphis, Tennessee, in January 1929. The magazine was devoted to the music news of Memphis primarily but also included Mississippi.

Implementation Of Brain Breaks(R) In The Classroom And Its Effects On Attitudes Towards Physical Activity In A Chinese School Setting, Ke Zhou, Sensen He, Yanli Zhou, Biljana Popeska, Garry Kuan, Li Chen, Ming-Kai Chin, Magdalena Mo Ching Mok, Christopher R. Edginton, Ian Culpan, J. Larry Durstine

Faculty Publications

This study aimed to examine the effects of three-months of classroom-based Brain Breaks Physical Activity Solution (Brain Breaks®) on attitudes toward physical activity levels of primary school children in Henan Province, China. The participants were 704 children enrolled in grades 3–5 who were randomly assigned to either an experimental or a control group. The experimental group participated in Brain Breaks® video intervention for 3–5 min daily, at low-to-moderate intensity for three consecutive months. The control group resumed their normal routine. The children’s attitudes in both groups towards physical activity (PA) were evaluated using the self-reported Attitudes toward Physical Activity Scale …

Foreword, Jennifer Taub

Western New England Law Review

This Foreword highlights the central points of the Articles in Volume 43, Issue 1 of Western New England Law Review. The Article topics include emotional support animals, distribution rights for small beer brewers, fairness in accident insurance coverage, alternative legal education materials, and custody challenges for parents with abusive partners. Each share the identification of a perceived problem with the legal status quo and presents proposed solutions.

Legal Education—Open Your Casebooks Please: Identifying Open Access Alternatives To Langdell’S Legacy, Emma M. Wood, Misty N. Peltz-Steele

Western New England Law Review

Nonprofits, academic institutions, and educators have collaborated, at all academic levels, to create quality Open Educational Resources (OER) since that term was defined by UNESCO in 2002. These opensource educational materials are in the public domain and published under an open license, meaning that they can be freely copied, used, adapted, and re-shared with the public. They include not only textbooks but supplemental educational materials in various media formats. Their value is such that even federal and state legislatures are taking note and passing laws to incentivize the creation and use of OER in both secondary and higher education. Despite …

Identification Of Disease-Linked Hyperactivating Mutations In Ube3a Through Large-Scale Functional Variant Analysis, Joshua P. Steimel, Kellan Weston, Xiaoyi Gao, Jinghan Zhao, Susan Maloney, Jill Gotoff, Sumit Parikh, Marwan Shinawi, Joseph Harrison

All Faculty Articles - School of Engineering and Computer Science

The mechanisms that underlie the extensive phenotypic diversity in genetic disorders are poorly understood. Here, we develop a large-scale assay to characterize the functional valence (gain or loss-of-function) of missense variants identified in UBE3A, the gene whose loss-of-function causes the neurodevelopmental disorder Angelman syndrome. We identify numerous gain-of-function variants including a hyperactivating Q588E mutation that strikingly increases UBE3A activity above wild-type UBE3A levels. Mice carrying the Q588E mutation exhibit aberrant early-life motor and communication deficits, and individuals possessing hyperactivating UBE3A variants exhibit affected phenotypes that are distinguishable from Angelman syndrome. Additional structure-function analysis reveals that Q588 forms a regulatory site …

Mechanically Transduced Immunosorbent Assay To Measure Protein-Protein Interactions, Joshua P. Steimel, Joseph Harrison, Brian Strahl, Diego Sandoval, Michael Pappas, Kathyrn Randene, Christopher Petell

All Faculty Articles - School of Engineering and Computer Science

Measuring protein-protein interaction (PPI) affinities is fundamental to biochemistry. Yet, conventional methods rely upon the law of mass action and cannot measure many PPIs due to a scarcity of reagents and limitations in the measurable affinity ranges. Here, we present a novel technique that leverages the fundamental concept of friction to produce a mechanical signal that correlates to binding potential. The mechanically transduced immunosorbent (METRIS) assay utilizes rolling magnetic probes to measure PPI interaction affinities. METRIS measures the translational displacement of protein-coated particles on a protein-functionalized substrate. The translational displacement scales with the effective friction induced by a PPI, thus …

Balancing The Pedagogical And Practical Concerns In Remote Higher Education: A Cyberethnography, Jose Eos R. Trinidad, Samantha Joan Ackary, Lyka Janelle P. Pacleb, Sophia Sue Tabanao, Jan Llenzl Dagohoy

Interdisciplinary Studies Faculty Publications

The COVID-19 pandemic brought about physical school closures and quick transitions online, with universities making decisions for this new mode of instruction. Such decisions, however, were open to discussion and debates, particularly as students and instructors held varying concerns, experiences, and expectations for remote learning. We investigate what these debates are using a cyberethnography of a Facebook group for students and faculty, and an anonymous Freedom Wall page for students in the same university. The concerns centered on workload that balanced academic rigor and practical exigencies; learning modalities that balanced accountability and flexibility; and assessments that balanced academic integrity and …

Health And Wellness: An Honors First-Year Experience Assignment In Response To The Pandemic, Cathlena Martin

Honors in Practice Online Archive

Responding to pervasive mental and physical stresses of the COVID-19 crisis, the author assigns first-year students various routine wellness practices for one hour each week along with requisite reflective writing exercises. Student expectations, experiences, and outcomes are presented.

About The Authors

Honors in Practice Online Archive

No abstract provided.

Sheep & Goat Research Journal, Volume 36, 2021

Sheep and Goat Research Journal

Sheep & Goat Research Journal, Volume 36, 2021

Profit Efficiency Analysis Of Cassava Production In Enugu State, Nigeria, Oguejiofor J. Okorie, Ubokudom E. Okon, Anselm A. Enete

Journal for the Advancement of Developing Economies

This study analyzed the profit efficiency of smallholder cassava farmers in Enugu state, Nigeria. The study employed a multi-stage random sampling technique in selecting 240 cassava farm households who are registered in the Enugu State Fadama III project during the 2019 farming season. Data were collected using copies of structured questionnaire and interview schedule. Collected data were analyzed using descriptive and inferential statistics (stochastic frontier profit function model). Results showed that the majority (73.3%) of the household heads were male, with a mean age of 52 years. Additionally, the majority (78.5%) of the respondents were married, mean farm size of …

Biological Activity Of Saussurea Amara (L.) Dc., Shagjjav Oyungerel

Erforschung biologischer Ressourcen der Mongolei / Exploration into the Biological Resources of Mongolia, ISSN 0440-1298

The medicinal application of specific plants over the long period in traditional medicine, suggests the presence of biologically active substances in those plant species. Saussurea amara (L.) DC. is a wild plant with a high feeding value because of its high protein content, vitamins, and minerals. S. amara is used in the traditional Mongolian medicine for the treatment of hepato-biliary disorders. The goal of this study was to evaluate the antioxidant and antimicrobial activities of S. amara. The antioxidant capacity of a methanol extract of plants was evaluated by analyzing its DPPH free-radical scavenging activity and reducing power …

Blood Parasites Of Fish Of The Baikal Basin, T. R. Khamnueva, Darima R. Baldanova

Erforschung biologischer Ressourcen der Mongolei / Exploration into the Biological Resources of Mongolia, ISSN 0440-1298

Eight species of trypanosomes were found in nine species of fish in the Lake Baikal: Trypanosoma percae, T. amurensis, T. schulmani, T. dogieli, T. magna, T. sp.1, T. sp.2. Five species of trypanoplasms were detected in the blood of 13 species of Baikal fish: Trypanoplasma lomakini, T. littoralis, T. cotti, T. zaikai, T. sp. In the erythrocytes of the sand sculpin, Leocottus kesslerii were observed haemogregarins.

Der Kormoran Phalacrocorax Carbo In Der Mongolei, Michael Stubbe, Lucie Marie Baltz, Davaa Lchagvasuren, Lukas Kratzsch, Lara-Sophie Dey, Annegret Stubbe

Erforschung biologischer Ressourcen der Mongolei / Exploration into the Biological Resources of Mongolia, ISSN 0440-1298

The Great Cormorant Phalacrocorax carbo is a wide spread breeding species in Mongolia with a progressive population trend. Observations of the Mongolian-German Biological Expeditions were analyzed and summarized with data from literature. About 1,500 young birds were ringed in 2016 and 2017. One important recovery was coming from the wintering area Mai Po Marshes Nature Reserve of Hong Kong. It is unclear if all Mongolian Cormorants are flying at the same route to their wintering region in South China. The main feeding fishes in Mongolia belong to endemic species of the genus Oreoleuciscus (Cyprinidae). Measurements of 113 eggs from Tolbo- …

Mist-Netting Of Forest-Dwelling Bats In The Lazovsky State Nature Reserve, Russian Far East, Kerstin Birlenbach

Erforschung biologischer Ressourcen der Mongolei / Exploration into the Biological Resources of Mongolia, ISSN 0440-1298

Many bat species depend on a high value of healthy and undisturbed forests with a high ratio of roost sites in old tree stands. This investigation focused on the diversity, distribution and reproduction status of bats within the area of Lazovsky State Nature Reserve. The importance of an area for bats can be measured by the ratio of reproduction. The most important and sensitive time in a bats yearly circle is the time of hibernation in winter and the reproduction time of females. From the beginning of July to the end of August 2007, in total 139 bats of eight …